4WZVA

Crystal structure of a hydroxamate based inhibitor en140 in complex with the mmp-9 catalytic domain
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
158
structure length
158
Chain Sequence
GDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGVGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Matrix metalloproteinase-9,Matrix metalloproteinase-9
total genus 45
structure length 158
sequence length 158
chains with identical sequence B
ec nomenclature ec 3.4.24.35: Gelatinase B.
pdb deposition date 2014-11-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4wzvA00
1MMQA 5I12A 1DMTA 2DDYA 2J83A 3ELMA 4FVLA 4PKQA 1BUVM 2D1OA 2OW9A 5JMYA 4FXYP 3GBOA 5D1TA 1ZVXA 3SHIA 3O2XA 1SATA 2OVXA 4H1QA 2KRJA 1WNIA 4GR8A 3MA2A 3EDIA 2W14A 2J0TA 4GQLA 3E8RA 3P24A 4CTHA 1QUAA 3F19A 4WZVA 3TT4A 3KECA 4GF1A 1GKCA 4I35A 3AYUA 2X7MA 2OXUA 5BPAA 5CUHA 4DPEA 4XCTA 1KUFA 3F1AA 2OXZA 1CXVA 1BM6A 3TVCA 1XURA 1D5JA 1UMSA 1BZSA 2W15A 1GKDA 2L0RA 4PKSA 830CA 2JT5A 3LEAA 1IABA 3WV2A 3OHLA 1XUCA 2JT6A 1DTHA 2OI0A 4R3VA 2OY4A 2EROA 2RJPA 5D1SA 5D1UA 1BKCI 1HOVA 1UMTA 3N2UA 5I0LA 1R1IA 2WO8A 2JNPA 2YIGA 1ROSA 4WF6A 1UTZA 4H82A 2MLRA 2X3BA 4L19A 1R55A 456CA 1QJJA 2JSDA 3HYGA 1CGEA 1BKCA 4L6TA 1IADA 3LQ0A 2PJTA 2HU6A 1C8TA 1IACA 3Q2HA 1JKYA 1JJ9A 1B3DA 2OZRA 4H49A 1OS9A 2X3CA 4L63A 3RTTA 4AIGA 3EHXA 4ZR5A 2CLTA 3ZUKA 1AYKA 3ZVSA 4I03A 2W12A 4JIJA 1RMZA 4EFSA 2DW0A 3EHYA 1R54A 4DD8A 2K2GA 2POJA 2W13A 2DW1A 3KEKA 2SRTA 3HBVP 3WV1A 5I4OA 1XFUA 3Q2GA 1K7QA 2O36A 4H76A 1A86A 1OS2A 2K9CA 3F15A 2E3XA 1Y8JA 1C3IA 1MMPA 1OMJA 3LUMA 4H3XA 4WK7A 1H71P 4QKZA 4WKIA 1SMPA 4H2EA 2MZIA 1JAOA 1HV5A 1XFZA 4FXQA 1ZP5A 3DSLA 3DL1A 2DDFA 4PKWA 1PWPA 1G49A 2I47A 1ZTQA 4GR0A 1BQQM 4Q1LA 4XBHA 1HY7A 3I7GA 1MMRA 4JP4A 1FM1A 2A8HA 2RJQA 1MMBA 3LMCA 1I73A 1HFCA 3KMEA 5D2BA 1BIWA 1GXDA 1I1IP 5LABA 1JIZA 1G05A 3LKAA 3EDZA 1G4KA 4DV8A 5B5OA 2O3EA 1KUHA 1FLSA 1D8FA 1G12A 3OHOA 1JH1A 1MNCA 1J7NA 1ZXVA 4J4MA 3TSKA 3DPEA 2OY2A 4PKTA 5I2ZA 5L7FA 2FV9A 2AYKA 1A85A 3HBUP 1BSWA 2FV5A 5L79A 1CQRA 1IAGA 2Y6DA 3EWJA 3HB2P 4IN9A 3AYKA 966CA 1KUKA 3B2ZA 1ND1A 1OM6A 1B8YA 3UVCA 1G9KA 5BOYA 2OXWA 2QPJA 3F16A 3TS4A 4HX3A 1RM8A 2WO9A 1Z3JA 1YCMA 1HTDA 3O64A 2YB9A 4A7BA 3G42A 4PKUA 1GE6A 1O0QA 1YP1A 2W0DA 3DPFA 2JIHA 1SRPA 1KUGA 4AXQA 1O0TA 1XFXA 5B5PA 1D7XA 1GO7P 2OVZA 3LUNA 3HY7A 4GR3A 4G9LA 4XM8A 1EUBA 1JAQA 3KRYA 2DW2A 1SLNA 1CAQA 2Y6CA 1QICA 3K7LA 2ERPA 4G0DA 1QJIA 1AKLA 4FU4A 1KAPP 2XS4A 1EB6A 2MZEA 3EDGA 1AF0A 2Z2DA 1XFVA 1QIBA 4DF9A 3LGPA 2AIGP 3HY9A 4PKVA 1Q3AA 4XM6A 3G5CA 3NX7A 4IJOA 3L0TA 2TCLA 4XM7A 3V96B 3VI1A 1CK7A 3EDHA 4JA1A 1C7KA 3AIGA 3VTGA 1CGFA 1PWQA 1USNA 3RTSA 3LJGA 4AUOA 1BQOA 2WOAA 1BKCE 4JPAA 4ILWD 3B8ZA 4HMAA 3HDBA 3ZXHA 1UEAA 3F17A 1SU3A 1IAEA 1PWWA 1ZXCA 1SLMA 5I43A 1XFYA 3LILA 3KHIA 1EAKA 3K7NA 1I76A 4WKEA 1PWUA 3LE9A 3WV3A 1XUDA 1JIWP 1QIAA 1K7IA 4GWNA 3L0VA 3CKIA 2CKIA 3B92A 2ERQA 1IAAA 3LJZA 3KMCA 3BA0A 1JK3A 5CZMA 5I3MA 1KUIA 4GWMA 1UTTA 1CGLA 5BOTA 3F18A 4JQGA 4IUWA 3U1RA 1GO8P 1R1HA 1JAPA 1K7GA 2MLSA 3LQBA 3LK8A 1FBLA 3KEJA 1GE5A 1OO9A 2USNA 2E2DA 1ATLA 2OW0A 1KBCA 2V4BA 1CIZA 2OW1A 3HDAP 3LJTA 3KWVC 1OM7A 1OM8A 2OW2A 1YQYA 4GUYA 2X3AA 2XS3A 1R1JA 1Y93A 1L6JA 1JANA 1S4BP 1Y0VA 3DWBA 5CXAA 3P1VA 4A3WA 4ON1A 1ASTA 2MZHA 3LIRA 2N8RA 3DNGA 3N2VA 4H30A 5D3CA 1D8MA 3I7IA 1PWVA 1YOUA 1BUDA 5H8XA 2D1NA 1HFSA 3USNA 1ZS0A 4H84A 4AYKA 4PKRA 1XFWA 5D7WA 1GE7A 3LIKA
chains in the Genus database with same CATH superfamily
1MMQA 5I12A 1DMTA 2DDYA 2J83A 3ELMA 4FVLA 4PKQA 1BUVM 2D1OA 2OW9A 5JMYA 4FXYP 3GBOA 5D1TA 1ZVXA 3SHIA 3O2XA 1SATA 2OVXA 4H1QA 2KRJA 1WNIA 4GR8A 3MA2A 3EDIA 2W14A 2J0TA 4GQLA 3E8RA 3P24A 4CTHA 1QUAA 3F19A 4WZVA 3TT4A 3KECA 4GF1A 1GKCA 4I35A 3AYUA 2X7MA 2OXUA 5BPAA 5CUHA 4DPEA 4XCTA 1KUFA 3F1AA 2OXZA 1CXVA 1BM6A 3TVCA 1XURA 1D5JA 1UMSA 1BZSA 2W15A 1GKDA 2L0RA 4PKSA 830CA 2JT5A 3LEAA 1IABA 3WV2A 3OHLA 1XUCA 2JT6A 1DTHA 2OI0A 4R3VA 2OY4A 2EROA 2RJPA 5D1SA 1TVIA 5D1UA 1BKCI 1HOVA 1UMTA 3N2UA 5I0LA 1R1IA 2WO8A 2JNPA 2YIGA 1ROSA 4WF6A 1UTZA 4H82A 2MLRA 2X3BA 4L19A 1R55A 456CA 1QJJA 2JSDA 3HYGA 1CGEA 1BKCA 4L6TA 1IADA 3LQ0A 2PJTA 2HU6A 1C8TA 1IACA 3Q2HA 1JKYA 1JJ9A 1B3DA 2OZRA 4H49A 1OS9A 2X3CA 4L63A 3RTTA 4AIGA 3EHXA 4ZR5A 2CLTA 3ZUKA 1AYKA 3ZVSA 4I03A 2W12A 1XM5A 4JIJA 1RMZA 4EFSA 2DW0A 3EHYA 1R54A 4DD8A 2K2GA 2POJA 2W13A 2DW1A 3KEKA 2SRTA 3HBVP 3WV1A 5I4OA 1XFUA 3Q2GA 1K7QA 2O36A 4H76A 1A86A 1OS2A 2K9CA 3F15A 2E3XA 1Y8JA 1C3IA 1MMPA 1OMJA 3LUMA 4H3XA 4WK7A 1H71P 4QKZA 4WKIA 1SMPA 4H2EA 2MZIA 1JAOA 1HV5A 1XFZA 4FXQA 1ZP5A 3DSLA 3DL1A 2DDFA 3DTKA 4PKWA 1PWPA 1G49A 2I47A 1ZTQA 4GR0A 1BQQM 4Q1LA 4XBHA 1HY7A 3I7GA 1MMRA 4JP4A 1FM1A 2A8HA 2RJQA 1MMBA 3LMCA 1I73A 1HFCA 3KMEA 5D2BA 1BIWA 1GXDA 1I1IP 5LABA 1JIZA 1G05A 3LKAA 3EDZA 1G4KA 4DV8A 5B5OA 2O3EA 1KUHA 1FLSA 1D8FA 1G12A 3OHOA 1JH1A 1MNCA 1J7NA 1ZXVA 4J4MA 3TSKA 3DPEA 2OY2A 4PKTA 5I2ZA 5L7FA 2FV9A 2AYKA 1A85A 2YUFA 3HBUP 1BSWA 2FV5A 5L79A 1CQRA 1IAGA 2Y6DA 1OZ9A 3EWJA 3HB2P 4IN9A 3AYKA 966CA 1KUKA 3B2ZA 1ND1A 1OM6A 1B8YA 3UVCA 1G9KA 5BOYA 2OXWA 2QPJA 3F16A 3TS4A 4HX3A 1RM8A 2WO9A 1Z3JA 1YCMA 1HTDA 3O64A 2YB9A 4A7BA 3DTIA 3G42A 4PKUA 1GE6A 1O0QA 1YP1A 2W0DA 3DPFA 2JIHA 1SRPA 1KUGA 4AXQA 1O0TA 1XFXA 5B5PA 1D7XA 1GO7P 2OVZA 3LUNA 3HY7A 4GR3A 4G9LA 4XM8A 1EUBA 1JAQA 3KRYA 2DW2A 1SLNA 1CAQA 2Y6CA 1QICA 3K7LA 2ERPA 4G0DA 1QJIA 1AKLA 4FU4A 1KAPP 2XS4A 1EB6A 2MZEA 3EDGA 1AF0A 2Z2DA 1XFVA 1QIBA 4DF9A 3LGPA 2AIGP 3HY9A 4PKVA 1Q3AA 4XM6A 3G5CA 3NX7A 4IJOA 3L0TA 2TCLA 4XM7A 3V96B 3VI1A 1CK7A 3EDHA 4JA1A 1C7KA 3AIGA 3VTGA 1CGFA 1PWQA 1USNA 3RTSA 1XAXA 3LJGA 4AUOA 1BQOA 2WOAA 1BKCE 4JPAA 4ILWD 3B8ZA 4HMAA 3HDBA 3ZXHA 1UEAA 3F17A 1SU3A 1IAEA 1PWWA 1ZXCA 1SLMA 5I43A 1XFYA 3LILA 3KHIA 1EAKA 3K7NA 1I76A 4WKEA 1PWUA 3LE9A 3WV3A 1XUDA 1JIWP 1QIAA 1K7IA 4GWNA 3L0VA 3CKIA 2CKIA 3B92A 2ERQA 1IAAA 3LJZA 3KMCA 3BA0A 1JK3A 5CZMA 5I3MA 1KUIA 4GWMA 1UTTA 1CGLA 5BOTA 3F18A 4JQGA 4IUWA 3U1RA 1GO8P 1R1HA 4L7AA 1JAPA 1K7GA 2MLSA 3LQBA 3LK8A 1FBLA 3KEJA 1GE5A 1OO9A 2USNA 2E2DA 1ATLA 2OW0A 1KBCA 2V4BA 1CIZA 2OW1A 3HDAP 3LJTA 3KWVC 1OM7A 1OM8A 2OW2A 1YQYA 4GUYA 2X3AA 2XS3A 1R1JA 1Y93A 1L6JA 1JANA 1S4BP 1Y0VA 3DTEA 3DWBA 3P1VA 5CXAA 4A3WA 4ON1A 1ASTA 2MZHA 3LIRA 2N8RA 3DNGA 3N2VA 4H30A 5D3CA 1D8MA 3I7IA 1PWVA 1YOUA 1BUDA 5H8XA 2D1NA 1HFSA 3USNA 1ZS0A 4H84A 4AYKA 4PKRA 1XFWA 5D7WA 1GE7A 3LIKA
chains in the Genus database with same CATH topology
1MMQA 5I12A 1DMTA 2DDYA 2J83A 3ELMA 4FVLA 4PKQA 1BUVM 2D1OA 2OW9A 5JMYA 4FXYP 3GBOA 5D1TA 1ZVXA 3SHIA 3O2XA 1SATA 2OVXA 4H1QA 2KRJA 1WNIA 4GR8A 3MA2A 3EDIA 2W14A 2J0TA 4GQLA 3E8RA 3P24A 4CTHA 1QUAA 3F19A 4WZVA 3TT4A 3KECA 4GF1A 1GKCA 4I35A 3AYUA 2X7MA 2OXUA 5BPAA 5CUHA 4DPEA 4XCTA 1KUFA 3F1AA 2OXZA 1CXVA 1BM6A 3TVCA 1XURA 1D5JA 1UMSA 1BZSA 2W15A 1GKDA 2L0RA 4PKSA 830CA 2JT5A 3LEAA 1IABA 3WV2A 3OHLA 1XUCA 2JT6A 1DTHA 2OI0A 4R3VA 2OY4A 2EROA 2RJPA 5D1SA 5D1UA 1BKCI 1HOVA 1UMTA 3N2UA 5I0LA 1R1IA 2WO8A 2JNPA 2YIGA 1ROSA 4WF6A 1UTZA 4H82A 2MLRA 2X3BA 4L19A 1R55A 456CA 1QJJA 2JSDA 3HYGA 1CGEA 1BKCA 4L6TA 1IADA 3LQ0A 2PJTA 2HU6A 1C8TA 1IACA 3Q2HA 1JKYA 1JJ9A 1B3DA 2OZRA 4H49A 1OS9A 2X3CA 4L63A 3RTTA 4AIGA 3EHXA 4ZR5A 2CLTA 3ZUKA 1AYKA 3ZVSA 4I03A 2W12A 4JIJA 1RMZA 4EFSA 2DW0A 3EHYA 1R54A 4DD8A 2K2GA 2POJA 2W13A 2DW1A 3KEKA 2SRTA 3HBVP 3WV1A 5I4OA 1XFUA 3Q2GA 1K7QA 2O36A 4H76A 1A86A 1OS2A 2K9CA 3F15A 2E3XA 1Y8JA 1C3IA 1MMPA 1OMJA 3LUMA 4H3XA 4WK7A 1H71P 4QKZA 4WKIA 1SMPA 4H2EA 2MZIA 1JAOA 1HV5A 1XFZA 4FXQA 1ZP5A 3DSLA 3DL1A 2DDFA 3DTKA 4PKWA 1PWPA 1G49A 2I47A 1ZTQA 4GR0A 1BQQM 4Q1LA 4XBHA 1HY7A 3I7GA 1MMRA 4JP4A 1FM1A 2A8HA 2RJQA 1MMBA 3LMCA 1I73A 1HFCA 3KMEA 5D2BA 1BIWA 1GXDA 1I1IP 5LABA 1JIZA 1G05A 3LKAA 3EDZA 1G4KA 4DV8A 5B5OA 2O3EA 1KUHA 1FLSA 1D8FA 1G12A 3OHOA 1JH1A 1MNCA 1J7NA 1ZXVA 4J4MA 3TSKA 3DPEA 2OY2A 4PKTA 5I2ZA 5L7FA 2FV9A 2AYKA 1A85A 2YUFA 3HBUP 1BSWA 2FV5A 5L79A 1CQRA 1IAGA 2Y6DA 3EWJA 3HB2P 4IN9A 3AYKA 966CA 1KUKA 3B2ZA 1ND1A 1OM6A 1B8YA 3UVCA 1G9KA 5BOYA 2OXWA 2QPJA 3F16A 3TS4A 4HX3A 1RM8A 2WO9A 1Z3JA 1YCMA 1HTDA 3O64A 2YB9A 4A7BA 3DTIA 3G42A 4PKUA 1GE6A 1O0QA 1YP1A 2W0DA 3DPFA 2JIHA 1SRPA 1KUGA 4AXQA 1O0TA 1XFXA 5B5PA 1D7XA 1GO7P 2OVZA 3LUNA 3HY7A 4GR3A 4G9LA 4XM8A 1EUBA 1JAQA 3KRYA 2DW2A 1SLNA 1CAQA 2Y6CA 1QICA 3K7LA 2ERPA 4G0DA 1QJIA 1AKLA 4FU4A 1KAPP 2XS4A 1EB6A 2MZEA 3EDGA 1AF0A 2Z2DA 1XFVA 1QIBA 4DF9A 3LGPA 2AIGP 3HY9A 4PKVA 1Q3AA 4XM6A 3G5CA 3NX7A 4IJOA 3L0TA 2TCLA 4XM7A 3V96B 3VI1A 1CK7A 3EDHA 4JA1A 1C7KA 3AIGA 3VTGA 1CGFA 1PWQA 1USNA 3RTSA 3LJGA 4AUOA 1BQOA 2WOAA 1BKCE 4JPAA 4ILWD 3B8ZA 4HMAA 3HDBA 3ZXHA 1UEAA 3F17A 1SU3A 1IAEA 1PWWA 1ZXCA 1SLMA 5I43A 1XFYA 3LILA 3KHIA 1EAKA 3K7NA 1I76A 4WKEA 1PWUA 3LE9A 3WV3A 1XUDA 1JIWP 1QIAA 1K7IA 4GWNA 3L0VA 3CKIA 2CKIA 3B92A 2ERQA 1IAAA 3LJZA 3KMCA 3BA0A 1JK3A 5CZMA 5I3MA 1KUIA 4GWMA 1UTTA 1CGLA 5BOTA 3F18A 4JQGA 4IUWA 3U1RA 1GO8P 1R1HA 4L7AA 1JAPA 1K7GA 2MLSA 3LQBA 3LK8A 1FBLA 3KEJA 1GE5A 1OO9A 2USNA 2E2DA 1ATLA 2OW0A 1KBCA 2V4BA 1CIZA 2OW1A 3HDAP 3LJTA 3KWVC 1OM7A 1OM8A 2OW2A 1YQYA 4GUYA 2X3AA 2XS3A 1R1JA 1Y93A 1L6JA 1JANA 1S4BP 1Y0VA 3DTEA 3DWBA 3P1VA 5CXAA 4A3WA 4ON1A 1ASTA 2MZHA 3LIRA 2N8RA 3DNGA 3N2VA 4H30A 5D3CA 1D8MA 3I7IA 1PWVA 1YOUA 1BUDA 5H8XA 2D1NA 1HFSA 3USNA 1ZS0A 4H84A 4AYKA 4PKRA 1XFWA 5D7WA 1GE7A 3LIKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MMQ A;  5I12 A;  1DMT A;  2DDY A;  2J83 A;  3ELM A;  4FVL A;  4PKQ A;  1BUV M;  2D1O A;  2OW9 A;  5JMY A;  4FXY P;  3GBO A;  5D1T A;  1ZVX A;  3SHI A;  3O2X A;  1SAT A;  2OVX A;  4H1Q A;  2KRJ A;  1WNI A;  4GR8 A;  3MA2 A;  3EDI A;  2W14 A;  2J0T A;  4GQL A;  3E8R A;  3P24 A;  4CTH A;  1QUA A;  3F19 A;  4WZV A;  3TT4 A;  3KEC A;  4GF1 A;  1GKC A;  4I35 A;  3AYU A;  2X7M A;  2OXU A;  5BPA A;  5CUH A;  4DPE A;  4XCT A;  1KUF A;  3F1A A;  2OXZ A;  1CXV A;  1BM6 A;  3TVC A;  1XUR A;  1D5J A;  1UMS A;  1BZS A;  2W15 A;  1GKD A;  2L0R A;  4PKS A;  830C A;  2JT5 A;  3LEA A;  1IAB A;  3WV2 A;  3OHL A;  1XUC A;  2JT6 A;  1DTH A;  2OI0 A;  4R3V A;  2OY4 A;  2ERO A;  2RJP A;  5D1S A;  5D1U A;  1BKC I;  1HOV A;  1UMT A;  3N2U A;  5I0L A;  1R1I A;  2WO8 A;  2JNP A;  2YIG A;  1ROS A;  4WF6 A;  1UTZ A;  4H82 A;  2MLR A;  2X3B A;  4L19 A;  1R55 A;  456C A;  1QJJ A;  2JSD A;  3HYG A;  1CGE A;  1BKC A;  4L6T A;  1IAD A;  3LQ0 A;  2PJT A;  2HU6 A;  1C8T A;  1IAC A;  3Q2H A;  1JKY A;  1JJ9 A;  1B3D A;  2OZR A;  4H49 A;  1OS9 A;  2X3C A;  4L63 A;  3RTT A;  4AIG A;  3EHX A;  4ZR5 A;  2CLT A;  3ZUK A;  1AYK A;  3ZVS A;  4I03 A;  2W12 A;  4JIJ A;  1RMZ A;  4EFS A;  2DW0 A;  3EHY A;  1R54 A;  4DD8 A;  2K2G A;  2POJ A;  2W13 A;  2DW1 A;  3KEK A;  2SRT A;  3HBV P;  3WV1 A;  5I4O A;  1XFU A;  3Q2G A;  1K7Q A;  2O36 A;  4H76 A;  1A86 A;  1OS2 A;  2K9C A;  3F15 A;  2E3X A;  1Y8J A;  1C3I A;  1MMP A;  1OMJ A;  3LUM A;  4H3X A;  4WK7 A;  1H71 P;  4QKZ A;  4WKI A;  1SMP A;  4H2E A;  2MZI A;  1JAO A;  1HV5 A;  1XFZ A;  4FXQ A;  1ZP5 A;  3DSL A;  3DL1 A;  2DDF A;  4PKW A;  1PWP A;  1G49 A;  2I47 A;  1ZTQ A;  4GR0 A;  1BQQ M;  4Q1L A;  4XBH A;  1HY7 A;  3I7G A;  1MMR A;  4JP4 A;  1FM1 A;  2A8H A;  2RJQ A;  1MMB A;  3LMC A;  1I73 A;  1HFC A;  3KME A;  5D2B A;  1BIW A;  1GXD A;  1I1I P;  5LAB A;  1JIZ A;  1G05 A;  3LKA A;  3EDZ A;  1G4K A;  4DV8 A;  5B5O A;  2O3E A;  1KUH A;  1FLS A;  1D8F A;  1G12 A;  3OHO A;  1JH1 A;  1MNC A;  1J7N A;  1ZXV A;  4J4M A;  3TSK A;  3DPE A;  2OY2 A;  4PKT A;  5I2Z A;  5L7F A;  2FV9 A;  2AYK A;  1A85 A;  3HBU P;  1BSW A;  2FV5 A;  5L79 A;  1CQR A;  1IAG A;  2Y6D A;  3EWJ A;  3HB2 P;  4IN9 A;  3AYK A;  966C A;  1KUK A;  3B2Z A;  1ND1 A;  1OM6 A;  1B8Y A;  3UVC A;  1G9K A;  5BOY A;  2OXW A;  2QPJ A;  3F16 A;  3TS4 A;  4HX3 A;  1RM8 A;  2WO9 A;  1Z3J A;  1YCM A;  1HTD A;  3O64 A;  2YB9 A;  4A7B A;  3G42 A;  4PKU A;  1GE6 A;  1O0Q A;  1YP1 A;  2W0D A;  3DPF A;  2JIH A;  1SRP A;  1KUG A;  4AXQ A;  1O0T A;  1XFX A;  5B5P A;  1D7X A;  1GO7 P;  2OVZ A;  3LUN A;  3HY7 A;  4GR3 A;  4G9L A;  4XM8 A;  1EUB A;  1JAQ A;  3KRY A;  2DW2 A;  1SLN A;  1CAQ A;  2Y6C A;  1QIC A;  3K7L A;  2ERP A;  4G0D A;  1QJI A;  1AKL A;  4FU4 A;  1KAP P;  2XS4 A;  1EB6 A;  2MZE A;  3EDG A;  1AF0 A;  2Z2D A;  1XFV A;  1QIB A;  4DF9 A;  3LGP A;  2AIG P;  3HY9 A;  4PKV A;  1Q3A A;  4XM6 A;  3G5C A;  3NX7 A;  4IJO A;  3L0T A;  2TCL A;  4XM7 A;  3V96 B;  3VI1 A;  1CK7 A;  3EDH A;  4JA1 A;  1C7K A;  3AIG A;  3VTG A;  1CGF A;  1PWQ A;  1USN A;  3RTS A;  3LJG A;  4AUO A;  1BQO A;  2WOA A;  1BKC E;  4JPA A;  4ILW D;  3B8Z A;  4HMA A;  3HDB A;  3ZXH A;  1UEA A;  3F17 A;  1SU3 A;  1IAE A;  1PWW A;  1ZXC A;  1SLM A;  5I43 A;  1XFY A;  3LIL A;  3KHI A;  1EAK A;  3K7N A;  1I76 A;  4WKE A;  1PWU A;  3LE9 A;  3WV3 A;  1XUD A;  1JIW P;  1QIA A;  1K7I A;  4GWN A;  3L0V A;  3CKI A;  2CKI A;  3B92 A;  2ERQ A;  1IAA A;  3LJZ A;  3KMC A;  3BA0 A;  1JK3 A;  5CZM A;  5I3M A;  1KUI A;  4GWM A;  1UTT A;  1CGL A;  5BOT A;  3F18 A;  4JQG A;  4IUW A;  3U1R A;  1GO8 P;  1R1H A;  1JAP A;  1K7G A;  2MLS A;  3LQB A;  3LK8 A;  1FBL A;  3KEJ A;  1GE5 A;  1OO9 A;  2USN A;  2E2D A;  1ATL A;  2OW0 A;  1KBC A;  2V4B A;  1CIZ A;  2OW1 A;  3HDA P;  3LJT A;  3KWV C;  1OM7 A;  1OM8 A;  2OW2 A;  1YQY A;  4GUY A;  2X3A A;  2XS3 A;  1R1J A;  1Y93 A;  1L6J A;  1JAN A;  1S4B P;  1Y0V A;  3DWB A;  5CXA A;  3P1V A;  4A3W A;  4ON1 A;  1AST A;  2MZH A;  3LIR A;  2N8R A;  3DNG A;  3N2V A;  4H30 A;  5D3C A;  1D8M A;  3I7I A;  1PWV A;  1YOU A;  1BUD A;  5H8X A;  2D1N A;  1HFS A;  3USN A;  1ZS0 A;  4H84 A;  4AYK A;  4PKR A;  1XFW A;  5D7W A;  1GE7 A;  3LIK A; 
#chains in the Genus database with same CATH topology
 1MMQ A;  5I12 A;  1DMT A;  2DDY A;  2J83 A;  3ELM A;  4FVL A;  4PKQ A;  1BUV M;  2D1O A;  2OW9 A;  5JMY A;  4FXY P;  3GBO A;  5D1T A;  1ZVX A;  3SHI A;  3O2X A;  1SAT A;  2OVX A;  4H1Q A;  2KRJ A;  1WNI A;  4GR8 A;  3MA2 A;  3EDI A;  2W14 A;  2J0T A;  4GQL A;  3E8R A;  3P24 A;  4CTH A;  1QUA A;  3F19 A;  4WZV A;  3TT4 A;  3KEC A;  4GF1 A;  1GKC A;  4I35 A;  3AYU A;  2X7M A;  2OXU A;  5BPA A;  5CUH A;  4DPE A;  4XCT A;  1KUF A;  3F1A A;  2OXZ A;  1CXV A;  1BM6 A;  3TVC A;  1XUR A;  1D5J A;  1UMS A;  1BZS A;  2W15 A;  1GKD A;  2L0R A;  4PKS A;  830C A;  2JT5 A;  3LEA A;  1IAB A;  3WV2 A;  3OHL A;  1XUC A;  2JT6 A;  1DTH A;  2OI0 A;  4R3V A;  2OY4 A;  2ERO A;  2RJP A;  5D1S A;  1TVI A;  5D1U A;  1BKC I;  1HOV A;  1UMT A;  3N2U A;  5I0L A;  1R1I A;  2WO8 A;  2JNP A;  2YIG A;  1ROS A;  4WF6 A;  1UTZ A;  4H82 A;  2MLR A;  2X3B A;  4L19 A;  1R55 A;  456C A;  1QJJ A;  2JSD A;  3HYG A;  1CGE A;  1BKC A;  4L6T A;  1IAD A;  3LQ0 A;  2PJT A;  2HU6 A;  1C8T A;  1IAC A;  3Q2H A;  1JKY A;  1JJ9 A;  1B3D A;  2OZR A;  4H49 A;  1OS9 A;  2X3C A;  4L63 A;  3RTT A;  4AIG A;  3EHX A;  4ZR5 A;  2CLT A;  3ZUK A;  1AYK A;  3ZVS A;  4I03 A;  2W12 A;  1XM5 A;  4JIJ A;  1RMZ A;  4EFS A;  2DW0 A;  3EHY A;  1R54 A;  4DD8 A;  2K2G A;  2POJ A;  2W13 A;  2DW1 A;  3KEK A;  2SRT A;  3HBV P;  3WV1 A;  5I4O A;  1XFU A;  3Q2G A;  1K7Q A;  2O36 A;  4H76 A;  1A86 A;  1OS2 A;  2K9C A;  3F15 A;  2E3X A;  1Y8J A;  1C3I A;  1MMP A;  1OMJ A;  3LUM A;  4H3X A;  4WK7 A;  1H71 P;  4QKZ A;  4WKI A;  1SMP A;  4H2E A;  2MZI A;  1JAO A;  1HV5 A;  1XFZ A;  4FXQ A;  1ZP5 A;  3DSL A;  3DL1 A;  2DDF A;  3DTK A;  4PKW A;  1PWP A;  1G49 A;  2I47 A;  1ZTQ A;  4GR0 A;  1BQQ M;  4Q1L A;  4XBH A;  1HY7 A;  3I7G A;  1MMR A;  4JP4 A;  1FM1 A;  2A8H A;  2RJQ A;  1MMB A;  3LMC A;  1I73 A;  1HFC A;  3KME A;  5D2B A;  1BIW A;  1GXD A;  1I1I P;  5LAB A;  1JIZ A;  1G05 A;  3LKA A;  3EDZ A;  1G4K A;  4DV8 A;  5B5O A;  2O3E A;  1KUH A;  1FLS A;  1D8F A;  1G12 A;  3OHO A;  1JH1 A;  1MNC A;  1J7N A;  1ZXV A;  4J4M A;  3TSK A;  3DPE A;  2OY2 A;  4PKT A;  5I2Z A;  5L7F A;  2FV9 A;  2AYK A;  1A85 A;  2YUF A;  3HBU P;  1BSW A;  2FV5 A;  5L79 A;  1CQR A;  1IAG A;  2Y6D A;  1OZ9 A;  3EWJ A;  3HB2 P;  4IN9 A;  3AYK A;  966C A;  1KUK A;  3B2Z A;  1ND1 A;  1OM6 A;  1B8Y A;  3UVC A;  1G9K A;  5BOY A;  2OXW A;  2QPJ A;  3F16 A;  3TS4 A;  4HX3 A;  1RM8 A;  2WO9 A;  1Z3J A;  1YCM A;  1HTD A;  3O64 A;  2YB9 A;  4A7B A;  3DTI A;  3G42 A;  4PKU A;  1GE6 A;  1O0Q A;  1YP1 A;  2W0D A;  3DPF A;  2JIH A;  1SRP A;  1KUG A;  4AXQ A;  1O0T A;  1XFX A;  5B5P A;  1D7X A;  1GO7 P;  2OVZ A;  3LUN A;  3HY7 A;  4GR3 A;  4G9L A;  4XM8 A;  1EUB A;  1JAQ A;  3KRY A;  2DW2 A;  1SLN A;  1CAQ A;  2Y6C A;  1QIC A;  3K7L A;  2ERP A;  4G0D A;  1QJI A;  1AKL A;  4FU4 A;  1KAP P;  2XS4 A;  1EB6 A;  2MZE A;  3EDG A;  1AF0 A;  2Z2D A;  1XFV A;  1QIB A;  4DF9 A;  3LGP A;  2AIG P;  3HY9 A;  4PKV A;  1Q3A A;  4XM6 A;  3G5C A;  3NX7 A;  4IJO A;  3L0T A;  2TCL A;  4XM7 A;  3V96 B;  3VI1 A;  1CK7 A;  3EDH A;  4JA1 A;  1C7K A;  3AIG A;  3VTG A;  1CGF A;  1PWQ A;  1USN A;  3RTS A;  1XAX A;  3LJG A;  4AUO A;  1BQO A;  2WOA A;  1BKC E;  4JPA A;  4ILW D;  3B8Z A;  4HMA A;  3HDB A;  3ZXH A;  1UEA A;  3F17 A;  1SU3 A;  1IAE A;  1PWW A;  1ZXC A;  1SLM A;  5I43 A;  1XFY A;  3LIL A;  3KHI A;  1EAK A;  3K7N A;  1I76 A;  4WKE A;  1PWU A;  3LE9 A;  3WV3 A;  1XUD A;  1JIW P;  1QIA A;  1K7I A;  4GWN A;  3L0V A;  3CKI A;  2CKI A;  3B92 A;  2ERQ A;  1IAA A;  3LJZ A;  3KMC A;  3BA0 A;  1JK3 A;  5CZM A;  5I3M A;  1KUI A;  4GWM A;  1UTT A;  1CGL A;  5BOT A;  3F18 A;  4JQG A;  4IUW A;  3U1R A;  1GO8 P;  1R1H A;  4L7A A;  1JAP A;  1K7G A;  2MLS A;  3LQB A;  3LK8 A;  1FBL A;  3KEJ A;  1GE5 A;  1OO9 A;  2USN A;  2E2D A;  1ATL A;  2OW0 A;  1KBC A;  2V4B A;  1CIZ A;  2OW1 A;  3HDA P;  3LJT A;  3KWV C;  1OM7 A;  1OM8 A;  2OW2 A;  1YQY A;  4GUY A;  2X3A A;  2XS3 A;  1R1J A;  1Y93 A;  1L6J A;  1JAN A;  1S4B P;  1Y0V A;  3DTE A;  3DWB A;  3P1V A;  5CXA A;  4A3W A;  4ON1 A;  1AST A;  2MZH A;  3LIR A;  2N8R A;  3DNG A;  3N2V A;  4H30 A;  5D3C A;  1D8M A;  3I7I A;  1PWV A;  1YOU A;  1BUD A;  5H8X A;  2D1N A;  1HFS A;  3USN A;  1ZS0 A;  4H84 A;  4AYK A;  4PKR A;  1XFW A;  5D7W A;  1GE7 A;  3LIK A; 
#chains in the Genus database with same CATH homology
 1MMQ A;  5I12 A;  1DMT A;  2DDY A;  2J83 A;  3ELM A;  4FVL A;  4PKQ A;  1BUV M;  2D1O A;  2OW9 A;  5JMY A;  4FXY P;  3GBO A;  5D1T A;  1ZVX A;  3SHI A;  3O2X A;  1SAT A;  2OVX A;  4H1Q A;  2KRJ A;  1WNI A;  4GR8 A;  3MA2 A;  3EDI A;  2W14 A;  2J0T A;  4GQL A;  3E8R A;  3P24 A;  4CTH A;  1QUA A;  3F19 A;  4WZV A;  3TT4 A;  3KEC A;  4GF1 A;  1GKC A;  4I35 A;  3AYU A;  2X7M A;  2OXU A;  5BPA A;  5CUH A;  4DPE A;  4XCT A;  1KUF A;  3F1A A;  2OXZ A;  1CXV A;  1BM6 A;  3TVC A;  1XUR A;  1D5J A;  1UMS A;  1BZS A;  2W15 A;  1GKD A;  2L0R A;  4PKS A;  830C A;  2JT5 A;  3LEA A;  1IAB A;  3WV2 A;  3OHL A;  1XUC A;  2JT6 A;  1DTH A;  2OI0 A;  4R3V A;  2OY4 A;  2ERO A;  2RJP A;  5D1S A;  5D1U A;  1BKC I;  1HOV A;  1UMT A;  3N2U A;  5I0L A;  1R1I A;  2WO8 A;  2JNP A;  2YIG A;  1ROS A;  4WF6 A;  1UTZ A;  4H82 A;  2MLR A;  2X3B A;  4L19 A;  1R55 A;  456C A;  1QJJ A;  2JSD A;  3HYG A;  1CGE A;  1BKC A;  4L6T A;  1IAD A;  3LQ0 A;  2PJT A;  2HU6 A;  1C8T A;  1IAC A;  3Q2H A;  1JKY A;  1JJ9 A;  1B3D A;  2OZR A;  4H49 A;  1OS9 A;  2X3C A;  4L63 A;  3RTT A;  4AIG A;  3EHX A;  4ZR5 A;  2CLT A;  3ZUK A;  1AYK A;  3ZVS A;  4I03 A;  2W12 A;  4JIJ A;  1RMZ A;  4EFS A;  2DW0 A;  3EHY A;  1R54 A;  4DD8 A;  2K2G A;  2POJ A;  2W13 A;  2DW1 A;  3KEK A;  2SRT A;  3HBV P;  3WV1 A;  5I4O A;  1XFU A;  3Q2G A;  1K7Q A;  2O36 A;  4H76 A;  1A86 A;  1OS2 A;  2K9C A;  3F15 A;  2E3X A;  1Y8J A;  1C3I A;  1MMP A;  1OMJ A;  3LUM A;  4H3X A;  4WK7 A;  1H71 P;  4QKZ A;  4WKI A;  1SMP A;  4H2E A;  2MZI A;  1JAO A;  1HV5 A;  1XFZ A;  4FXQ A;  1ZP5 A;  3DSL A;  3DL1 A;  2DDF A;  3DTK A;  4PKW A;  1PWP A;  1G49 A;  2I47 A;  1ZTQ A;  4GR0 A;  1BQQ M;  4Q1L A;  4XBH A;  1HY7 A;  3I7G A;  1MMR A;  4JP4 A;  1FM1 A;  2A8H A;  2RJQ A;  1MMB A;  3LMC A;  1I73 A;  1HFC A;  3KME A;  5D2B A;  1BIW A;  1GXD A;  1I1I P;  5LAB A;  1JIZ A;  1G05 A;  3LKA A;  3EDZ A;  1G4K A;  4DV8 A;  5B5O A;  2O3E A;  1KUH A;  1FLS A;  1D8F A;  1G12 A;  3OHO A;  1JH1 A;  1MNC A;  1J7N A;  1ZXV A;  4J4M A;  3TSK A;  3DPE A;  2OY2 A;  4PKT A;  5I2Z A;  5L7F A;  2FV9 A;  2AYK A;  1A85 A;  2YUF A;  3HBU P;  1BSW A;  2FV5 A;  5L79 A;  1CQR A;  1IAG A;  2Y6D A;  3EWJ A;  3HB2 P;  4IN9 A;  3AYK A;  966C A;  1KUK A;  3B2Z A;  1ND1 A;  1OM6 A;  1B8Y A;  3UVC A;  1G9K A;  5BOY A;  2OXW A;  2QPJ A;  3F16 A;  3TS4 A;  4HX3 A;  1RM8 A;  2WO9 A;  1Z3J A;  1YCM A;  1HTD A;  3O64 A;  2YB9 A;  4A7B A;  3DTI A;  3G42 A;  4PKU A;  1GE6 A;  1O0Q A;  1YP1 A;  2W0D A;  3DPF A;  2JIH A;  1SRP A;  1KUG A;  4AXQ A;  1O0T A;  1XFX A;  5B5P A;  1D7X A;  1GO7 P;  2OVZ A;  3LUN A;  3HY7 A;  4GR3 A;  4G9L A;  4XM8 A;  1EUB A;  1JAQ A;  3KRY A;  2DW2 A;  1SLN A;  1CAQ A;  2Y6C A;  1QIC A;  3K7L A;  2ERP A;  4G0D A;  1QJI A;  1AKL A;  4FU4 A;  1KAP P;  2XS4 A;  1EB6 A;  2MZE A;  3EDG A;  1AF0 A;  2Z2D A;  1XFV A;  1QIB A;  4DF9 A;  3LGP A;  2AIG P;  3HY9 A;  4PKV A;  1Q3A A;  4XM6 A;  3G5C A;  3NX7 A;  4IJO A;  3L0T A;  2TCL A;  4XM7 A;  3V96 B;  3VI1 A;  1CK7 A;  3EDH A;  4JA1 A;  1C7K A;  3AIG A;  3VTG A;  1CGF A;  1PWQ A;  1USN A;  3RTS A;  3LJG A;  4AUO A;  1BQO A;  2WOA A;  1BKC E;  4JPA A;  4ILW D;  3B8Z A;  4HMA A;  3HDB A;  3ZXH A;  1UEA A;  3F17 A;  1SU3 A;  1IAE A;  1PWW A;  1ZXC A;  1SLM A;  5I43 A;  1XFY A;  3LIL A;  3KHI A;  1EAK A;  3K7N A;  1I76 A;  4WKE A;  1PWU A;  3LE9 A;  3WV3 A;  1XUD A;  1JIW P;  1QIA A;  1K7I A;  4GWN A;  3L0V A;  3CKI A;  2CKI A;  3B92 A;  2ERQ A;  1IAA A;  3LJZ A;  3KMC A;  3BA0 A;  1JK3 A;  5CZM A;  5I3M A;  1KUI A;  4GWM A;  1UTT A;  1CGL A;  5BOT A;  3F18 A;  4JQG A;  4IUW A;  3U1R A;  1GO8 P;  1R1H A;  4L7A A;  1JAP A;  1K7G A;  2MLS A;  3LQB A;  3LK8 A;  1FBL A;  3KEJ A;  1GE5 A;  1OO9 A;  2USN A;  2E2D A;  1ATL A;  2OW0 A;  1KBC A;  2V4B A;  1CIZ A;  2OW1 A;  3HDA P;  3LJT A;  3KWV C;  1OM7 A;  1OM8 A;  2OW2 A;  1YQY A;  4GUY A;  2X3A A;  2XS3 A;  1R1J A;  1Y93 A;  1L6J A;  1JAN A;  1S4B P;  1Y0V A;  3DTE A;  3DWB A;  3P1V A;  5CXA A;  4A3W A;  4ON1 A;  1AST A;  2MZH A;  3LIR A;  2N8R A;  3DNG A;  3N2V A;  4H30 A;  5D3C A;  1D8M A;  3I7I A;  1PWV A;  1YOU A;  1BUD A;  5H8X A;  2D1N A;  1HFS A;  3USN A;  1ZS0 A;  4H84 A;  4AYK A;  4PKR A;  1XFW A;  5D7W A;  1GE7 A;  3LIK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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