5BPAA

X-ray co-structure of mmp-13 with 4-[({5-[2-(ethoxycarbonyl)-1h-indol-5-yl]-1-methyl-1h-pyrazol-3-yl}formamido)methyl]benzoate
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
169
structure length
169
Chain Sequence
YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGDED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Fragment-based discovery of indole inhibitors of matrix metalloproteinase-13.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Collagenase 3
total genus 48
structure length 169
sequence length 169
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2015-05-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 5bpaA00
1OS2A 1D7XA 1IAGA 2JSDA 2X3CA 1FLSA 3LJZA 5I12A 1QIBA 4JA1A 3KWVC 2JT6A 3WV1A 2V4BA 3HY9A 1Q3AA 2TCLA 5BOYA 2W14A 3N2VA 1CGEA 4G9LA 1R55A 2CLTA 1EUBA 4L63A 4JP4A 3MA2A 1L6JA 1IABA 1UMTA 4IUWA 1Y8JA 2RJQA 1KUIA 2XS3A 1BKCI 3B2ZA 1BSWA 2AYKA 1ZVXA 3VTGA 2W15A 4J4MA 2MZIA 2L0RA 966CA 4GQLA 4AXQA 3EWJA 1BKCE 2D1NA 2KRJA 2MZHA 1GKCA 3TSKA 1Y0VA 1OM7A 1HFCA 2DDYA 3I7GA 3LE9A 1K7QA 1KUKA 5B5OA 1HV5A 4FU4A 3HYGA 2DW0A 3ZVSA 1OS9A 2OW2A 3LEAA 1SMPA 1YP1A 2QPJA 3F17A 1Y93A 1I73A 1PWWA 1UTZA 1UEAA 3P24A 4ZR5A 3LJTA 2I47A 4IJOA 3LIKA 1XFUA 1R1HA 3KHIA 3EHXA 1JK3A 1BQOA 3Q2HA 1A86A 3ELMA 1A85A 1XFXA 2RJPA 2WOAA 3B8ZA 3N2UA 1UTTA 3F15A 2DDFA 1JAOA 1RM8A 4H3XA 1JJ9A 3ZXHA 2E2DA 2OVZA 1BZSA 5I4OA 3F18A 2YIGA 4IN9A 1CGLA 1BUVM 1DMTA 3HB2P 2MLSA 3EDHA 1GE7A 2POJA 3P1VA 1UMSA 1C3IA 1D8FA 1BIWA 1MMQA 5H8XA 2Y6CA 1Z3JA 5D1UA 3WV2A 2JIHA 4JIJA 2JT5A 3LQBA 4WZVA 3L0TA 1GO8P 4PKRA 1D5JA 1I1IP 2K2GA 1MMRA 1XUDA 456CA 5L79A 3I7IA 1XURA 2HU6A 3HDBA 2OXWA 3DSLA 3OHOA 1MNCA 3OHLA 2SRTA 1PWPA 1JIZA 3KMEA 2CKIA 1D8MA 4JPAA 2MLRA 3DPFA 4I03A 3HDAP 2EROA 1G49A 1GE6A 1ZTQA 1JANA 3O2XA 4GR3A 2Z2DA 4A7BA 1GKDA 1EB6A 2O3EA 1KUHA 4H2EA 3AYKA 1HOVA 4H49A 1KBCA 3EHYA 1BUDA 3RTSA 3WV3A 4WKIA 1SLNA 1S4BP 4PKSA 5D1TA 1B8YA 3EDGA 2FV5A 3L0VA 1YOUA 1SRPA 3TVCA 5D7WA 3DL1A 3AYUA 3BA0A 4H84A 4XCTA 2W13A 1QJIA 4GF1A 2Y6DA 3SHIA 3E8RA 1OO9A 2D1OA 1SU3A 2DW1A 2AIGP 1C8TA 1KAPP 3Q2GA 4PKVA 1OM6A 4L6TA 3KRYA 1CAQA 1IACA 3ZUKA 1QICA 2JNPA 2MZEA 1ND1A 4HX3A 1XUCA 1B3DA 3AIGA 1GO7P 1R54A 3K7LA 1ROSA 3K7NA 1IADA 4ILWD 4PKQA 4R3VA 2OW0A 2OXUA 1HTDA 3B92A 1I76A 1XFWA 3KEKA 3LJGA 4FXQA 1C7KA 5BPAA 4Q1LA 3F16A 1BKCA 4I35A 4DPEA 1MMPA 4ON1A 1CXVA 2OY2A 2XS4A 3VI1A 1JAPA 1ASTA 1HY7A 1DTHA 1AYKA 5LABA 4PKTA 3LKAA 2DW2A 1CQRA 4H76A 1AKLA 1BQQM 3LMCA 3USNA 1USNA 4XM6A 3G42A 4AUOA 2WO8A 3GBOA 4L19A 5D3CA 4FXYP 1XFZA 2N8RA 5L7FA 1IAAA 2OVXA 1MMBA 4XM7A 2O36A 1JKYA 1QJJA 4GR8A 5CUHA 4H1QA 2ERQA 1HFSA 3LK8A 1PWVA 4GR0A 2OXZA 4HMAA 1FBLA 5D2BA 1QIAA 4EFSA 1OMJA 3O64A 1YCMA 1KUGA 1R1IA 4WK7A 4WKEA 5BOTA 1PWQA 3LUMA 1ZS0A 4JQGA 2A8HA 3DPEA 5CXAA 3LGPA 3EDZA 2J83A 3NX7A 2W0DA 3UVCA 1JH1A 1AF0A 3V96B 1J7NA 1SLMA 3HY7A 5JMYA 4H82A 1FM1A 1O0QA 2OZRA 1K7GA 3F1AA 4GWMA 1YQYA 3TS4A 3DNGA 1ZXCA 2ERPA 3TT4A 2X3BA 1EAKA 4PKUA 1CK7A 4G0DA 2K9CA 2X7MA 1G05A 2OW9A 1RMZA 3G5CA 2OI0A 3LUNA 1K7IA 4GWNA 1OM8A 5CZMA 4A3WA 5I2ZA 1PWUA 3DWBA 3LIRA 3LQ0A 1SATA 1BM6A 2USNA 2E3XA 3HBVP 3LILA 2FV9A 1WNIA 1CIZA 1CGFA 1XFYA 3CKIA 1O0TA 3EDIA 1G9KA 5B5PA 1QUAA 3KECA 5I0LA 1ZP5A 4XM8A 4XBHA 1ZXVA 2PJTA 4WF6A 4DV8A 830CA 4DF9A 2OW1A 2WO9A 4DD8A 1JIWP 1KUFA 4FVLA 4GUYA 5I3MA 1GXDA 4CTHA 3RTTA 1ATLA 1GE5A 3KEJA 2W12A 2YB9A 1G4KA 2X3AA 2OY4A 2J0TA 3F19A 1H71P 3U1RA 1IAEA 3HBUP 4AYKA 4H30A 4PKWA 5I43A 1XFVA 5D1SA 1R1JA 1G12A 3KMCA 4AIGA 1JAQA 4QKZA
chains in the Genus database with same CATH superfamily
1OS2A 1D7XA 1IAGA 2JSDA 2X3CA 1FLSA 3LJZA 5I12A 1QIBA 4JA1A 3KWVC 2JT6A 3WV1A 2YUFA 2V4BA 3HY9A 1Q3AA 2TCLA 5BOYA 2W14A 3N2VA 1CGEA 4G9LA 1R55A 2CLTA 1EUBA 4L63A 4JP4A 3MA2A 1L6JA 1IABA 1UMTA 4IUWA 1Y8JA 2RJQA 1KUIA 2XS3A 1BKCI 3B2ZA 1BSWA 2AYKA 1ZVXA 3VTGA 2W15A 4J4MA 2MZIA 2L0RA 966CA 4GQLA 4AXQA 3EWJA 1BKCE 2D1NA 2KRJA 2MZHA 1GKCA 3TSKA 1Y0VA 1OM7A 1HFCA 2DDYA 3I7GA 3LE9A 1K7QA 1KUKA 1TVIA 5B5OA 1HV5A 4FU4A 3HYGA 2DW0A 3ZVSA 1OS9A 2OW2A 3LEAA 1SMPA 1YP1A 2QPJA 3F17A 1Y93A 1I73A 1PWWA 1UTZA 1UEAA 3P24A 4ZR5A 3LJTA 2I47A 4IJOA 3LIKA 1XFUA 1R1HA 3KHIA 3EHXA 1JK3A 1BQOA 3Q2HA 1A86A 3ELMA 1A85A 1XFXA 2RJPA 2WOAA 3B8ZA 3N2UA 1UTTA 3F15A 2DDFA 1JAOA 1RM8A 4H3XA 1JJ9A 1OZ9A 3ZXHA 2E2DA 2OVZA 1BZSA 5I4OA 3F18A 2YIGA 4IN9A 1CGLA 1BUVM 1DMTA 3HB2P 2MLSA 3EDHA 1GE7A 2POJA 3DTEA 3P1VA 1UMSA 1C3IA 1D8FA 1BIWA 1MMQA 3DTKA 5H8XA 2Y6CA 1Z3JA 5D1UA 3WV2A 2JIHA 4JIJA 2JT5A 3LQBA 4WZVA 3L0TA 1GO8P 4PKRA 1D5JA 1I1IP 2K2GA 1MMRA 1XUDA 456CA 5L79A 3I7IA 1XURA 2HU6A 3HDBA 2OXWA 3DSLA 3OHOA 1MNCA 3OHLA 2SRTA 1PWPA 1JIZA 3KMEA 2CKIA 1D8MA 4JPAA 2MLRA 3DPFA 4I03A 3HDAP 2EROA 1G49A 1XM5A 1GE6A 1ZTQA 1JANA 3O2XA 4GR3A 4L7AA 2Z2DA 4A7BA 1GKDA 1EB6A 2O3EA 1KUHA 4H2EA 3AYKA 1HOVA 4H49A 1KBCA 3EHYA 1BUDA 3RTSA 3WV3A 4WKIA 1SLNA 1S4BP 4PKSA 5D1TA 1B8YA 3EDGA 2FV5A 3L0VA 1YOUA 1SRPA 3TVCA 5D7WA 3DL1A 3AYUA 3BA0A 4H84A 4XCTA 2W13A 1QJIA 4GF1A 2Y6DA 3SHIA 3E8RA 1OO9A 2D1OA 1SU3A 2DW1A 2AIGP 1C8TA 1KAPP 3Q2GA 4PKVA 1OM6A 1XAXA 4L6TA 3KRYA 1CAQA 1IACA 3ZUKA 1QICA 2JNPA 2MZEA 1ND1A 4HX3A 1XUCA 1B3DA 3AIGA 1GO7P 1R54A 3K7LA 1ROSA 3K7NA 1IADA 4ILWD 4PKQA 4R3VA 2OW0A 2OXUA 1HTDA 3B92A 1I76A 1XFWA 3KEKA 3LJGA 4FXQA 1C7KA 5BPAA 4Q1LA 3F16A 1BKCA 4I35A 4DPEA 1MMPA 4ON1A 1CXVA 2OY2A 2XS4A 3VI1A 1JAPA 1ASTA 1HY7A 1DTHA 1AYKA 5LABA 4PKTA 3LKAA 2DW2A 1CQRA 4H76A 1AKLA 1BQQM 3LMCA 3USNA 1USNA 4XM6A 3G42A 4AUOA 2WO8A 3GBOA 4L19A 5D3CA 4FXYP 1XFZA 2N8RA 5L7FA 1IAAA 2OVXA 1MMBA 4XM7A 2O36A 1JKYA 1QJJA 3DTIA 4GR8A 5CUHA 4H1QA 2ERQA 1HFSA 3LK8A 1PWVA 4GR0A 2OXZA 4HMAA 1FBLA 5D2BA 1QIAA 4EFSA 1OMJA 3O64A 1YCMA 1KUGA 1R1IA 4WK7A 4WKEA 5BOTA 1PWQA 3LUMA 1ZS0A 4JQGA 2A8HA 3DPEA 5CXAA 3LGPA 3EDZA 2J83A 3NX7A 2W0DA 3UVCA 1JH1A 1AF0A 3V96B 1J7NA 1SLMA 3HY7A 5JMYA 4H82A 1FM1A 1O0QA 2OZRA 1K7GA 3F1AA 4GWMA 1YQYA 3TS4A 3DNGA 1ZXCA 2ERPA 3TT4A 2X3BA 1EAKA 4PKUA 1CK7A 4G0DA 2K9CA 2X7MA 1G05A 2OW9A 1RMZA 3G5CA 2OI0A 3LUNA 1K7IA 4GWNA 1OM8A 5CZMA 4A3WA 5I2ZA 1PWUA 3DWBA 3LIRA 3LQ0A 1SATA 1BM6A 2USNA 2E3XA 3HBVP 3LILA 2FV9A 1WNIA 1CIZA 1CGFA 1XFYA 3CKIA 1O0TA 3EDIA 1G9KA 5B5PA 1QUAA 3KECA 5I0LA 1ZP5A 4XM8A 4XBHA 1ZXVA 2PJTA 4WF6A 4DV8A 830CA 4DF9A 2OW1A 2WO9A 4DD8A 1JIWP 1KUFA 4FVLA 4GUYA 5I3MA 1GXDA 4CTHA 3RTTA 1ATLA 1GE5A 3KEJA 2W12A 2YB9A 1G4KA 2X3AA 2OY4A 2J0TA 3F19A 1H71P 3U1RA 1IAEA 3HBUP 4AYKA 4H30A 4PKWA 5I43A 1XFVA 5D1SA 1R1JA 1G12A 3KMCA 4AIGA 1JAQA 4QKZA
chains in the Genus database with same CATH topology
1OS2A 1D7XA 1IAGA 2JSDA 2X3CA 1FLSA 3LJZA 5I12A 1QIBA 4JA1A 3KWVC 2JT6A 3WV1A 2YUFA 2V4BA 3HY9A 1Q3AA 2TCLA 5BOYA 2W14A 3N2VA 1CGEA 4G9LA 1R55A 2CLTA 1EUBA 4L63A 4JP4A 3MA2A 1L6JA 1IABA 1UMTA 4IUWA 1Y8JA 2RJQA 1KUIA 2XS3A 1BKCI 3B2ZA 1BSWA 2AYKA 1ZVXA 3VTGA 2W15A 4J4MA 2MZIA 2L0RA 966CA 4GQLA 4AXQA 3EWJA 1BKCE 2D1NA 2KRJA 2MZHA 1GKCA 3TSKA 1Y0VA 1OM7A 1HFCA 2DDYA 3I7GA 3LE9A 1K7QA 1KUKA 5B5OA 1HV5A 4FU4A 3HYGA 2DW0A 3ZVSA 1OS9A 2OW2A 3LEAA 1SMPA 1YP1A 2QPJA 3F17A 1Y93A 1I73A 1PWWA 1UTZA 1UEAA 3P24A 4ZR5A 3LJTA 2I47A 4IJOA 3LIKA 1XFUA 1R1HA 3KHIA 3EHXA 1JK3A 1BQOA 3Q2HA 1A86A 3ELMA 1A85A 1XFXA 2RJPA 2WOAA 3B8ZA 3N2UA 1UTTA 3F15A 2DDFA 1JAOA 1RM8A 4H3XA 1JJ9A 3ZXHA 2E2DA 2OVZA 1BZSA 5I4OA 3F18A 2YIGA 4IN9A 1CGLA 1BUVM 1DMTA 3HB2P 2MLSA 3EDHA 1GE7A 2POJA 3DTEA 3P1VA 1UMSA 1C3IA 1D8FA 1BIWA 1MMQA 3DTKA 5H8XA 2Y6CA 1Z3JA 5D1UA 3WV2A 2JIHA 4JIJA 2JT5A 3LQBA 4WZVA 3L0TA 1GO8P 4PKRA 1D5JA 1I1IP 2K2GA 1MMRA 1XUDA 456CA 5L79A 3I7IA 1XURA 2HU6A 3HDBA 2OXWA 3DSLA 3OHOA 1MNCA 3OHLA 2SRTA 1PWPA 1JIZA 3KMEA 2CKIA 1D8MA 4JPAA 2MLRA 3DPFA 4I03A 3HDAP 2EROA 1G49A 1GE6A 1ZTQA 1JANA 3O2XA 4GR3A 4L7AA 2Z2DA 4A7BA 1GKDA 1EB6A 2O3EA 1KUHA 4H2EA 3AYKA 1HOVA 4H49A 1KBCA 3EHYA 1BUDA 3RTSA 3WV3A 4WKIA 1SLNA 1S4BP 4PKSA 5D1TA 1B8YA 3EDGA 2FV5A 3L0VA 1YOUA 1SRPA 3TVCA 5D7WA 3DL1A 3AYUA 3BA0A 4H84A 4XCTA 2W13A 1QJIA 4GF1A 2Y6DA 3SHIA 3E8RA 1OO9A 2D1OA 1SU3A 2DW1A 2AIGP 1C8TA 1KAPP 3Q2GA 4PKVA 1OM6A 4L6TA 3KRYA 1CAQA 1IACA 3ZUKA 1QICA 2JNPA 2MZEA 1ND1A 4HX3A 1XUCA 1B3DA 3AIGA 1GO7P 1R54A 3K7LA 1ROSA 3K7NA 1IADA 4ILWD 4PKQA 4R3VA 2OW0A 2OXUA 1HTDA 3B92A 1I76A 1XFWA 3KEKA 3LJGA 4FXQA 1C7KA 5BPAA 4Q1LA 3F16A 1BKCA 4I35A 4DPEA 1MMPA 4ON1A 1CXVA 2OY2A 2XS4A 3VI1A 1JAPA 1ASTA 1HY7A 1DTHA 1AYKA 5LABA 4PKTA 3LKAA 2DW2A 1CQRA 4H76A 1AKLA 1BQQM 3LMCA 3USNA 1USNA 4XM6A 3G42A 4AUOA 2WO8A 3GBOA 4L19A 5D3CA 4FXYP 1XFZA 2N8RA 5L7FA 1IAAA 2OVXA 1MMBA 4XM7A 2O36A 1JKYA 1QJJA 3DTIA 4GR8A 5CUHA 4H1QA 2ERQA 1HFSA 3LK8A 1PWVA 4GR0A 2OXZA 4HMAA 1FBLA 5D2BA 1QIAA 4EFSA 1OMJA 3O64A 1YCMA 1KUGA 1R1IA 4WK7A 4WKEA 5BOTA 1PWQA 3LUMA 1ZS0A 4JQGA 2A8HA 3DPEA 5CXAA 3LGPA 3EDZA 2J83A 3NX7A 2W0DA 3UVCA 1JH1A 1AF0A 3V96B 1J7NA 1SLMA 3HY7A 5JMYA 4H82A 1FM1A 1O0QA 2OZRA 1K7GA 3F1AA 4GWMA 1YQYA 3TS4A 3DNGA 1ZXCA 2ERPA 3TT4A 2X3BA 1EAKA 4PKUA 1CK7A 4G0DA 2K9CA 2X7MA 1G05A 2OW9A 1RMZA 3G5CA 2OI0A 3LUNA 1K7IA 4GWNA 1OM8A 5CZMA 4A3WA 5I2ZA 1PWUA 3DWBA 3LIRA 3LQ0A 1SATA 1BM6A 2USNA 2E3XA 3HBVP 3LILA 2FV9A 1WNIA 1CIZA 1CGFA 1XFYA 3CKIA 1O0TA 3EDIA 1G9KA 5B5PA 1QUAA 3KECA 5I0LA 1ZP5A 4XM8A 4XBHA 1ZXVA 2PJTA 4WF6A 4DV8A 830CA 4DF9A 2OW1A 2WO9A 4DD8A 1JIWP 1KUFA 4FVLA 4GUYA 5I3MA 1GXDA 4CTHA 3RTTA 1ATLA 1GE5A 3KEJA 2W12A 2YB9A 1G4KA 2X3AA 2OY4A 2J0TA 3F19A 1H71P 3U1RA 1IAEA 3HBUP 4AYKA 4H30A 4PKWA 5I43A 1XFVA 5D1SA 1R1JA 1G12A 3KMCA 4AIGA 1JAQA 4QKZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OS2 A;  1D7X A;  1IAG A;  2JSD A;  2X3C A;  1FLS A;  3LJZ A;  5I12 A;  1QIB A;  4JA1 A;  3KWV C;  2JT6 A;  3WV1 A;  2V4B A;  3HY9 A;  1Q3A A;  2TCL A;  5BOY A;  2W14 A;  3N2V A;  1CGE A;  4G9L A;  1R55 A;  2CLT A;  1EUB A;  4L63 A;  4JP4 A;  3MA2 A;  1L6J A;  1IAB A;  1UMT A;  4IUW A;  1Y8J A;  2RJQ A;  1KUI A;  2XS3 A;  1BKC I;  3B2Z A;  1BSW A;  2AYK A;  1ZVX A;  3VTG A;  2W15 A;  4J4M A;  2MZI A;  2L0R A;  966C A;  4GQL A;  4AXQ A;  3EWJ A;  1BKC E;  2D1N A;  2KRJ A;  2MZH A;  1GKC A;  3TSK A;  1Y0V A;  1OM7 A;  1HFC A;  2DDY A;  3I7G A;  3LE9 A;  1K7Q A;  1KUK A;  5B5O A;  1HV5 A;  4FU4 A;  3HYG A;  2DW0 A;  3ZVS A;  1OS9 A;  2OW2 A;  3LEA A;  1SMP A;  1YP1 A;  2QPJ A;  3F17 A;  1Y93 A;  1I73 A;  1PWW A;  1UTZ A;  1UEA A;  3P24 A;  4ZR5 A;  3LJT A;  2I47 A;  4IJO A;  3LIK A;  1XFU A;  1R1H A;  3KHI A;  3EHX A;  1JK3 A;  1BQO A;  3Q2H A;  1A86 A;  3ELM A;  1A85 A;  1XFX A;  2RJP A;  2WOA A;  3B8Z A;  3N2U A;  1UTT A;  3F15 A;  2DDF A;  1JAO A;  1RM8 A;  4H3X A;  1JJ9 A;  3ZXH A;  2E2D A;  2OVZ A;  1BZS A;  5I4O A;  3F18 A;  2YIG A;  4IN9 A;  1CGL A;  1BUV M;  1DMT A;  3HB2 P;  2MLS A;  3EDH A;  1GE7 A;  2POJ A;  3P1V A;  1UMS A;  1C3I A;  1D8F A;  1BIW A;  1MMQ A;  5H8X A;  2Y6C A;  1Z3J A;  5D1U A;  3WV2 A;  2JIH A;  4JIJ A;  2JT5 A;  3LQB A;  4WZV A;  3L0T A;  1GO8 P;  4PKR A;  1D5J A;  1I1I P;  2K2G A;  1MMR A;  1XUD A;  456C A;  5L79 A;  3I7I A;  1XUR A;  2HU6 A;  3HDB A;  2OXW A;  3DSL A;  3OHO A;  1MNC A;  3OHL A;  2SRT A;  1PWP A;  1JIZ A;  3KME A;  2CKI A;  1D8M A;  4JPA A;  2MLR A;  3DPF A;  4I03 A;  3HDA P;  2ERO A;  1G49 A;  1GE6 A;  1ZTQ A;  1JAN A;  3O2X A;  4GR3 A;  2Z2D A;  4A7B A;  1GKD A;  1EB6 A;  2O3E A;  1KUH A;  4H2E A;  3AYK A;  1HOV A;  4H49 A;  1KBC A;  3EHY A;  1BUD A;  3RTS A;  3WV3 A;  4WKI A;  1SLN A;  1S4B P;  4PKS A;  5D1T A;  1B8Y A;  3EDG A;  2FV5 A;  3L0V A;  1YOU A;  1SRP A;  3TVC A;  5D7W A;  3DL1 A;  3AYU A;  3BA0 A;  4H84 A;  4XCT A;  2W13 A;  1QJI A;  4GF1 A;  2Y6D A;  3SHI A;  3E8R A;  1OO9 A;  2D1O A;  1SU3 A;  2DW1 A;  2AIG P;  1C8T A;  1KAP P;  3Q2G A;  4PKV A;  1OM6 A;  4L6T A;  3KRY A;  1CAQ A;  1IAC A;  3ZUK A;  1QIC A;  2JNP A;  2MZE A;  1ND1 A;  4HX3 A;  1XUC A;  1B3D A;  3AIG A;  1GO7 P;  1R54 A;  3K7L A;  1ROS A;  3K7N A;  1IAD A;  4ILW D;  4PKQ A;  4R3V A;  2OW0 A;  2OXU A;  1HTD A;  3B92 A;  1I76 A;  1XFW A;  3KEK A;  3LJG A;  4FXQ A;  1C7K A;  5BPA A;  4Q1L A;  3F16 A;  1BKC A;  4I35 A;  4DPE A;  1MMP A;  4ON1 A;  1CXV A;  2OY2 A;  2XS4 A;  3VI1 A;  1JAP A;  1AST A;  1HY7 A;  1DTH A;  1AYK A;  5LAB A;  4PKT A;  3LKA A;  2DW2 A;  1CQR A;  4H76 A;  1AKL A;  1BQQ M;  3LMC A;  3USN A;  1USN A;  4XM6 A;  3G42 A;  4AUO A;  2WO8 A;  3GBO A;  4L19 A;  5D3C A;  4FXY P;  1XFZ A;  2N8R A;  5L7F A;  1IAA A;  2OVX A;  1MMB A;  4XM7 A;  2O36 A;  1JKY A;  1QJJ A;  4GR8 A;  5CUH A;  4H1Q A;  2ERQ A;  1HFS A;  3LK8 A;  1PWV A;  4GR0 A;  2OXZ A;  4HMA A;  1FBL A;  5D2B A;  1QIA A;  4EFS A;  1OMJ A;  3O64 A;  1YCM A;  1KUG A;  1R1I A;  4WK7 A;  4WKE A;  5BOT A;  1PWQ A;  3LUM A;  1ZS0 A;  4JQG A;  2A8H A;  3DPE A;  5CXA A;  3LGP A;  3EDZ A;  2J83 A;  3NX7 A;  2W0D A;  3UVC A;  1JH1 A;  1AF0 A;  3V96 B;  1J7N A;  1SLM A;  3HY7 A;  5JMY A;  4H82 A;  1FM1 A;  1O0Q A;  2OZR A;  1K7G A;  3F1A A;  4GWM A;  1YQY A;  3TS4 A;  3DNG A;  1ZXC A;  2ERP A;  3TT4 A;  2X3B A;  1EAK A;  4PKU A;  1CK7 A;  4G0D A;  2K9C A;  2X7M A;  1G05 A;  2OW9 A;  1RMZ A;  3G5C A;  2OI0 A;  3LUN A;  1K7I A;  4GWN A;  1OM8 A;  5CZM A;  4A3W A;  5I2Z A;  1PWU A;  3DWB A;  3LIR A;  3LQ0 A;  1SAT A;  1BM6 A;  2USN A;  2E3X A;  3HBV P;  3LIL A;  2FV9 A;  1WNI A;  1CIZ A;  1CGF A;  1XFY A;  3CKI A;  1O0T A;  3EDI A;  1G9K A;  5B5P A;  1QUA A;  3KEC A;  5I0L A;  1ZP5 A;  4XM8 A;  4XBH A;  1ZXV A;  2PJT A;  4WF6 A;  4DV8 A;  830C A;  4DF9 A;  2OW1 A;  2WO9 A;  4DD8 A;  1JIW P;  1KUF A;  4FVL A;  4GUY A;  5I3M A;  1GXD A;  4CTH A;  3RTT A;  1ATL A;  1GE5 A;  3KEJ A;  2W12 A;  2YB9 A;  1G4K A;  2X3A A;  2OY4 A;  2J0T A;  3F19 A;  1H71 P;  3U1R A;  1IAE A;  3HBU P;  4AYK A;  4H30 A;  4PKW A;  5I43 A;  1XFV A;  5D1S A;  1R1J A;  1G12 A;  3KMC A;  4AIG A;  1JAQ A;  4QKZ A; 
#chains in the Genus database with same CATH topology
 1OS2 A;  1D7X A;  1IAG A;  2JSD A;  2X3C A;  1FLS A;  3LJZ A;  5I12 A;  1QIB A;  4JA1 A;  3KWV C;  2JT6 A;  3WV1 A;  2YUF A;  2V4B A;  3HY9 A;  1Q3A A;  2TCL A;  5BOY A;  2W14 A;  3N2V A;  1CGE A;  4G9L A;  1R55 A;  2CLT A;  1EUB A;  4L63 A;  4JP4 A;  3MA2 A;  1L6J A;  1IAB A;  1UMT A;  4IUW A;  1Y8J A;  2RJQ A;  1KUI A;  2XS3 A;  1BKC I;  3B2Z A;  1BSW A;  2AYK A;  1ZVX A;  3VTG A;  2W15 A;  4J4M A;  2MZI A;  2L0R A;  966C A;  4GQL A;  4AXQ A;  3EWJ A;  1BKC E;  2D1N A;  2KRJ A;  2MZH A;  1GKC A;  3TSK A;  1Y0V A;  1OM7 A;  1HFC A;  2DDY A;  3I7G A;  3LE9 A;  1K7Q A;  1KUK A;  1TVI A;  5B5O A;  1HV5 A;  4FU4 A;  3HYG A;  2DW0 A;  3ZVS A;  1OS9 A;  2OW2 A;  3LEA A;  1SMP A;  1YP1 A;  2QPJ A;  3F17 A;  1Y93 A;  1I73 A;  1PWW A;  1UTZ A;  1UEA A;  3P24 A;  4ZR5 A;  3LJT A;  2I47 A;  4IJO A;  3LIK A;  1XFU A;  1R1H A;  3KHI A;  3EHX A;  1JK3 A;  1BQO A;  3Q2H A;  1A86 A;  3ELM A;  1A85 A;  1XFX A;  2RJP A;  2WOA A;  3B8Z A;  3N2U A;  1UTT A;  3F15 A;  2DDF A;  1JAO A;  1RM8 A;  4H3X A;  1JJ9 A;  1OZ9 A;  3ZXH A;  2E2D A;  2OVZ A;  1BZS A;  5I4O A;  3F18 A;  2YIG A;  4IN9 A;  1CGL A;  1BUV M;  1DMT A;  3HB2 P;  2MLS A;  3EDH A;  1GE7 A;  2POJ A;  3DTE A;  3P1V A;  1UMS A;  1C3I A;  1D8F A;  1BIW A;  1MMQ A;  3DTK A;  5H8X A;  2Y6C A;  1Z3J A;  5D1U A;  3WV2 A;  2JIH A;  4JIJ A;  2JT5 A;  3LQB A;  4WZV A;  3L0T A;  1GO8 P;  4PKR A;  1D5J A;  1I1I P;  2K2G A;  1MMR A;  1XUD A;  456C A;  5L79 A;  3I7I A;  1XUR A;  2HU6 A;  3HDB A;  2OXW A;  3DSL A;  3OHO A;  1MNC A;  3OHL A;  2SRT A;  1PWP A;  1JIZ A;  3KME A;  2CKI A;  1D8M A;  4JPA A;  2MLR A;  3DPF A;  4I03 A;  3HDA P;  2ERO A;  1G49 A;  1XM5 A;  1GE6 A;  1ZTQ A;  1JAN A;  3O2X A;  4GR3 A;  4L7A A;  2Z2D A;  4A7B A;  1GKD A;  1EB6 A;  2O3E A;  1KUH A;  4H2E A;  3AYK A;  1HOV A;  4H49 A;  1KBC A;  3EHY A;  1BUD A;  3RTS A;  3WV3 A;  4WKI A;  1SLN A;  1S4B P;  4PKS A;  5D1T A;  1B8Y A;  3EDG A;  2FV5 A;  3L0V A;  1YOU A;  1SRP A;  3TVC A;  5D7W A;  3DL1 A;  3AYU A;  3BA0 A;  4H84 A;  4XCT A;  2W13 A;  1QJI A;  4GF1 A;  2Y6D A;  3SHI A;  3E8R A;  1OO9 A;  2D1O A;  1SU3 A;  2DW1 A;  2AIG P;  1C8T A;  1KAP P;  3Q2G A;  4PKV A;  1OM6 A;  1XAX A;  4L6T A;  3KRY A;  1CAQ A;  1IAC A;  3ZUK A;  1QIC A;  2JNP A;  2MZE A;  1ND1 A;  4HX3 A;  1XUC A;  1B3D A;  3AIG A;  1GO7 P;  1R54 A;  3K7L A;  1ROS A;  3K7N A;  1IAD A;  4ILW D;  4PKQ A;  4R3V A;  2OW0 A;  2OXU A;  1HTD A;  3B92 A;  1I76 A;  1XFW A;  3KEK A;  3LJG A;  4FXQ A;  1C7K A;  5BPA A;  4Q1L A;  3F16 A;  1BKC A;  4I35 A;  4DPE A;  1MMP A;  4ON1 A;  1CXV A;  2OY2 A;  2XS4 A;  3VI1 A;  1JAP A;  1AST A;  1HY7 A;  1DTH A;  1AYK A;  5LAB A;  4PKT A;  3LKA A;  2DW2 A;  1CQR A;  4H76 A;  1AKL A;  1BQQ M;  3LMC A;  3USN A;  1USN A;  4XM6 A;  3G42 A;  4AUO A;  2WO8 A;  3GBO A;  4L19 A;  5D3C A;  4FXY P;  1XFZ A;  2N8R A;  5L7F A;  1IAA A;  2OVX A;  1MMB A;  4XM7 A;  2O36 A;  1JKY A;  1QJJ A;  3DTI A;  4GR8 A;  5CUH A;  4H1Q A;  2ERQ A;  1HFS A;  3LK8 A;  1PWV A;  4GR0 A;  2OXZ A;  4HMA A;  1FBL A;  5D2B A;  1QIA A;  4EFS A;  1OMJ A;  3O64 A;  1YCM A;  1KUG A;  1R1I A;  4WK7 A;  4WKE A;  5BOT A;  1PWQ A;  3LUM A;  1ZS0 A;  4JQG A;  2A8H A;  3DPE A;  5CXA A;  3LGP A;  3EDZ A;  2J83 A;  3NX7 A;  2W0D A;  3UVC A;  1JH1 A;  1AF0 A;  3V96 B;  1J7N A;  1SLM A;  3HY7 A;  5JMY A;  4H82 A;  1FM1 A;  1O0Q A;  2OZR A;  1K7G A;  3F1A A;  4GWM A;  1YQY A;  3TS4 A;  3DNG A;  1ZXC A;  2ERP A;  3TT4 A;  2X3B A;  1EAK A;  4PKU A;  1CK7 A;  4G0D A;  2K9C A;  2X7M A;  1G05 A;  2OW9 A;  1RMZ A;  3G5C A;  2OI0 A;  3LUN A;  1K7I A;  4GWN A;  1OM8 A;  5CZM A;  4A3W A;  5I2Z A;  1PWU A;  3DWB A;  3LIR A;  3LQ0 A;  1SAT A;  1BM6 A;  2USN A;  2E3X A;  3HBV P;  3LIL A;  2FV9 A;  1WNI A;  1CIZ A;  1CGF A;  1XFY A;  3CKI A;  1O0T A;  3EDI A;  1G9K A;  5B5P A;  1QUA A;  3KEC A;  5I0L A;  1ZP5 A;  4XM8 A;  4XBH A;  1ZXV A;  2PJT A;  4WF6 A;  4DV8 A;  830C A;  4DF9 A;  2OW1 A;  2WO9 A;  4DD8 A;  1JIW P;  1KUF A;  4FVL A;  4GUY A;  5I3M A;  1GXD A;  4CTH A;  3RTT A;  1ATL A;  1GE5 A;  3KEJ A;  2W12 A;  2YB9 A;  1G4K A;  2X3A A;  2OY4 A;  2J0T A;  3F19 A;  1H71 P;  3U1R A;  1IAE A;  3HBU P;  4AYK A;  4H30 A;  4PKW A;  5I43 A;  1XFV A;  5D1S A;  1R1J A;  1G12 A;  3KMC A;  4AIG A;  1JAQ A;  4QKZ A; 
#chains in the Genus database with same CATH homology
 1OS2 A;  1D7X A;  1IAG A;  2JSD A;  2X3C A;  1FLS A;  3LJZ A;  5I12 A;  1QIB A;  4JA1 A;  3KWV C;  2JT6 A;  3WV1 A;  2YUF A;  2V4B A;  3HY9 A;  1Q3A A;  2TCL A;  5BOY A;  2W14 A;  3N2V A;  1CGE A;  4G9L A;  1R55 A;  2CLT A;  1EUB A;  4L63 A;  4JP4 A;  3MA2 A;  1L6J A;  1IAB A;  1UMT A;  4IUW A;  1Y8J A;  2RJQ A;  1KUI A;  2XS3 A;  1BKC I;  3B2Z A;  1BSW A;  2AYK A;  1ZVX A;  3VTG A;  2W15 A;  4J4M A;  2MZI A;  2L0R A;  966C A;  4GQL A;  4AXQ A;  3EWJ A;  1BKC E;  2D1N A;  2KRJ A;  2MZH A;  1GKC A;  3TSK A;  1Y0V A;  1OM7 A;  1HFC A;  2DDY A;  3I7G A;  3LE9 A;  1K7Q A;  1KUK A;  5B5O A;  1HV5 A;  4FU4 A;  3HYG A;  2DW0 A;  3ZVS A;  1OS9 A;  2OW2 A;  3LEA A;  1SMP A;  1YP1 A;  2QPJ A;  3F17 A;  1Y93 A;  1I73 A;  1PWW A;  1UTZ A;  1UEA A;  3P24 A;  4ZR5 A;  3LJT A;  2I47 A;  4IJO A;  3LIK A;  1XFU A;  1R1H A;  3KHI A;  3EHX A;  1JK3 A;  1BQO A;  3Q2H A;  1A86 A;  3ELM A;  1A85 A;  1XFX A;  2RJP A;  2WOA A;  3B8Z A;  3N2U A;  1UTT A;  3F15 A;  2DDF A;  1JAO A;  1RM8 A;  4H3X A;  1JJ9 A;  3ZXH A;  2E2D A;  2OVZ A;  1BZS A;  5I4O A;  3F18 A;  2YIG A;  4IN9 A;  1CGL A;  1BUV M;  1DMT A;  3HB2 P;  2MLS A;  3EDH A;  1GE7 A;  2POJ A;  3DTE A;  3P1V A;  1UMS A;  1C3I A;  1D8F A;  1BIW A;  1MMQ A;  3DTK A;  5H8X A;  2Y6C A;  1Z3J A;  5D1U A;  3WV2 A;  2JIH A;  4JIJ A;  2JT5 A;  3LQB A;  4WZV A;  3L0T A;  1GO8 P;  4PKR A;  1D5J A;  1I1I P;  2K2G A;  1MMR A;  1XUD A;  456C A;  5L79 A;  3I7I A;  1XUR A;  2HU6 A;  3HDB A;  2OXW A;  3DSL A;  3OHO A;  1MNC A;  3OHL A;  2SRT A;  1PWP A;  1JIZ A;  3KME A;  2CKI A;  1D8M A;  4JPA A;  2MLR A;  3DPF A;  4I03 A;  3HDA P;  2ERO A;  1G49 A;  1GE6 A;  1ZTQ A;  1JAN A;  3O2X A;  4GR3 A;  4L7A A;  2Z2D A;  4A7B A;  1GKD A;  1EB6 A;  2O3E A;  1KUH A;  4H2E A;  3AYK A;  1HOV A;  4H49 A;  1KBC A;  3EHY A;  1BUD A;  3RTS A;  3WV3 A;  4WKI A;  1SLN A;  1S4B P;  4PKS A;  5D1T A;  1B8Y A;  3EDG A;  2FV5 A;  3L0V A;  1YOU A;  1SRP A;  3TVC A;  5D7W A;  3DL1 A;  3AYU A;  3BA0 A;  4H84 A;  4XCT A;  2W13 A;  1QJI A;  4GF1 A;  2Y6D A;  3SHI A;  3E8R A;  1OO9 A;  2D1O A;  1SU3 A;  2DW1 A;  2AIG P;  1C8T A;  1KAP P;  3Q2G A;  4PKV A;  1OM6 A;  4L6T A;  3KRY A;  1CAQ A;  1IAC A;  3ZUK A;  1QIC A;  2JNP A;  2MZE A;  1ND1 A;  4HX3 A;  1XUC A;  1B3D A;  3AIG A;  1GO7 P;  1R54 A;  3K7L A;  1ROS A;  3K7N A;  1IAD A;  4ILW D;  4PKQ A;  4R3V A;  2OW0 A;  2OXU A;  1HTD A;  3B92 A;  1I76 A;  1XFW A;  3KEK A;  3LJG A;  4FXQ A;  1C7K A;  5BPA A;  4Q1L A;  3F16 A;  1BKC A;  4I35 A;  4DPE A;  1MMP A;  4ON1 A;  1CXV A;  2OY2 A;  2XS4 A;  3VI1 A;  1JAP A;  1AST A;  1HY7 A;  1DTH A;  1AYK A;  5LAB A;  4PKT A;  3LKA A;  2DW2 A;  1CQR A;  4H76 A;  1AKL A;  1BQQ M;  3LMC A;  3USN A;  1USN A;  4XM6 A;  3G42 A;  4AUO A;  2WO8 A;  3GBO A;  4L19 A;  5D3C A;  4FXY P;  1XFZ A;  2N8R A;  5L7F A;  1IAA A;  2OVX A;  1MMB A;  4XM7 A;  2O36 A;  1JKY A;  1QJJ A;  3DTI A;  4GR8 A;  5CUH A;  4H1Q A;  2ERQ A;  1HFS A;  3LK8 A;  1PWV A;  4GR0 A;  2OXZ A;  4HMA A;  1FBL A;  5D2B A;  1QIA A;  4EFS A;  1OMJ A;  3O64 A;  1YCM A;  1KUG A;  1R1I A;  4WK7 A;  4WKE A;  5BOT A;  1PWQ A;  3LUM A;  1ZS0 A;  4JQG A;  2A8H A;  3DPE A;  5CXA A;  3LGP A;  3EDZ A;  2J83 A;  3NX7 A;  2W0D A;  3UVC A;  1JH1 A;  1AF0 A;  3V96 B;  1J7N A;  1SLM A;  3HY7 A;  5JMY A;  4H82 A;  1FM1 A;  1O0Q A;  2OZR A;  1K7G A;  3F1A A;  4GWM A;  1YQY A;  3TS4 A;  3DNG A;  1ZXC A;  2ERP A;  3TT4 A;  2X3B A;  1EAK A;  4PKU A;  1CK7 A;  4G0D A;  2K9C A;  2X7M A;  1G05 A;  2OW9 A;  1RMZ A;  3G5C A;  2OI0 A;  3LUN A;  1K7I A;  4GWN A;  1OM8 A;  5CZM A;  4A3W A;  5I2Z A;  1PWU A;  3DWB A;  3LIR A;  3LQ0 A;  1SAT A;  1BM6 A;  2USN A;  2E3X A;  3HBV P;  3LIL A;  2FV9 A;  1WNI A;  1CIZ A;  1CGF A;  1XFY A;  3CKI A;  1O0T A;  3EDI A;  1G9K A;  5B5P A;  1QUA A;  3KEC A;  5I0L A;  1ZP5 A;  4XM8 A;  4XBH A;  1ZXV A;  2PJT A;  4WF6 A;  4DV8 A;  830C A;  4DF9 A;  2OW1 A;  2WO9 A;  4DD8 A;  1JIW P;  1KUF A;  4FVL A;  4GUY A;  5I3M A;  1GXD A;  4CTH A;  3RTT A;  1ATL A;  1GE5 A;  3KEJ A;  2W12 A;  2YB9 A;  1G4K A;  2X3A A;  2OY4 A;  2J0T A;  3F19 A;  1H71 P;  3U1R A;  1IAE A;  3HBU P;  4AYK A;  4H30 A;  4PKW A;  5I43 A;  1XFV A;  5D1S A;  1R1J A;  1G12 A;  3KMC A;  4AIG A;  1JAQ A;  4QKZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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