5CXAA

Crystal structure of the catalytic domain of human mmp12 in complex with a carboxylate inhibitor related to rxp470
Total Genus 45
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
159
structure length
159
Chain Sequence
MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYAYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Zinc-Metalloproteinase Inhibitors: Evaluation of the Complex Role Played by the Zinc-Binding Group on Potency and Selectivity.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 45
structure length 159
sequence length 159
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2015-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 5cxaA00
1HTDA 1Y8JA 2OVXA 4G9LA 2MLRA 4I35A 4CTHA 3WV1A 4HMAA 1JAOA 2WOAA 1B8YA 4PKUA 1XFVA 3LKAA 3L0VA 1OM6A 1MMRA 2DDYA 3LQBA 1R1JA 3AYKA 4A7BA 1BQQM 1JKYA 2A8HA 4DF9A 1BZSA 1GO7P 2W15A 3I7IA 1KUGA 2I47A 2OZRA 2E3XA 2K2GA 1K7QA 2AYKA 2YIGA 1XURA 1AYKA 5D3CA 1D5JA 1GE7A 2J0TA 4GWMA 2OI0A 3GBOA 1MMQA 3DSLA 1R1HA 3B2ZA 4PKVA 2W12A 3RTSA 2X7MA 4XM8A 1G49A 1USNA 4R3VA 4L6TA 1GE6A 1KBCA 1R55A 1QJIA 4Q1LA 4AYKA 2W13A 1CGFA 4L63A 2FV5A 1GO8P 2JSDA 2JIHA 4WK7A 1BUVM 1ATLA 3TSKA 2X3BA 2E2DA 2USNA 3KRYA 4GWNA 1EB6A 1I1IP 3HDAP 1XUCA 2L0RA 4GR0A 4I03A 2V4BA 2RJQA 3LQ0A 3O64A 1PWVA 3HBVP 5B5OA 2O3EA 3DPEA 3AIGA 2X3AA 1GKDA 4DPEA 4GUYA 1FM1A 1R1IA 4EFSA 2JT5A 5JMYA 5I43A 2CLTA 2POJA 3DWBA 1CGLA 1QICA 1KUHA 3VI1A 3HY7A 1A86A 4GQLA 1KUKA 1IADA 2OW9A 3LEAA 5B5PA 1KUFA 3BA0A 3EDGA 2MLSA 5I0LA 1SATA 4GR8A 2OVZA 2Z2DA 4WKIA 3HY9A 3LIKA 1SLMA 1JK3A 1HFSA 2OW2A 4PKRA 1IABA 3CKIA 2OXWA 2W0DA 4FXYP 3EWJA 1ZS0A 5I4OA 4PKSA 3F18A 5D2BA 2JT6A 5D1TA 1H71P 3F16A 1UTZA 1CK7A 1D8FA 830CA 1YQYA 1O0QA 1RMZA 1B3DA 5L79A 3TVCA 2W14A 1IAAA 1OM7A 3F19A 1CIZA 2J83A 2AIGP 3DNGA 2ERQA 5L7FA 3EDHA 4JIJA 1ZXVA 3EHYA 3VTGA 4PKTA 3O2XA 4H30A 3NX7A 2N8RA 4XBHA 1CXVA 2TCLA 4WF6A 3LJGA 3B92A 1PWPA 1FLSA 4PKQA 1IAGA 4H2EA 3P1VA 2K9CA 2OW1A 4G0DA 3LUNA 1HY7A 1HFCA 1RM8A 3LMCA 1A85A 3I7GA 2DW0A 1AF0A 1UMTA 3WV3A 2X3CA 1QJJA 1SU3A 1CQRA 3LJTA 3TT4A 1XFXA 1GKCA 3ELMA 3RTTA 1UEAA 2JNPA 5D7WA 1K7GA 4FU4A 1I76A 4GF1A 1BIWA 1ZXCA 3DPFA 1ZTQA 1ZVXA 1YP1A 1HOVA 3KHIA 1DTHA 1MNCA 2RJPA 1G12A 1O0TA 4H3XA 2CKIA 1C7KA 3HYGA 3TS4A 4WZVA 1SMPA 1QUAA 2MZIA 4IN9A 4XCTA 5I12A 3F1AA 1ROSA 3HBUP 1JANA 1YOUA 3MA2A 4FVLA 1KUIA 1XFYA 1ASTA 2WO9A 5BOYA 4ILWD 2OXZA 4DD8A 4J4MA 1BKCE 1OMJA 3LUMA 2O36A 2Y6CA 1JAPA 4AXQA 456CA 4AUOA 2PJTA 3P24A 1BKCI 4XM7A 3LGPA 3K7NA 5CZMA 1Q3AA 2FV9A 1QIBA 3Q2HA 3ZXHA 3Q2GA 1DMTA 4DV8A 4XM6A 2OW0A 1KAPP 3K7LA 3HDBA 2XS4A 3USNA 3LE9A 3LK8A 3ZVSA 3UVCA 4H76A 3LILA 1G9KA 3AYUA 1GE5A 4H82A 1BKCA 1ZP5A 1XFZA 4IJOA 3N2UA 1EAKA 4A3WA 4HX3A 1YCMA 2OY4A 3LJZA 3OHOA 3DL1A 4H49A 1D8MA 2HU6A 4JP4A 3V96B 4GR3A 3F17A 966CA 1BQOA 5I3MA 1CGEA 1BUDA 3KMCA 4PKWA 1I73A 1UMSA 1C3IA 5D1UA 1C8TA 2ERPA 4FXQA 3KEKA 3EDIA 4JQGA 2EROA 2XS3A 1JIWP 1JAQA 2KRJA 5BOTA 4JPAA 3N2VA 1L6JA 3B8ZA 1G05A 3KWVC 5H8XA 1D7XA 3LIRA 1MMBA 1MMPA 2D1OA 3EHXA 1SLNA 1FBLA 4WKEA 3KMEA 1OM8A 2OXUA 2DW1A 3G5CA 1J7NA 1JJ9A 1IACA 2Y6DA 1AKLA 1IAEA 4H84A 2D1NA 5LABA 1OS2A 2OY2A 3WV2A 1R54A 3HB2P 3KEJA 3G42A 1G4KA 2WO8A 3EDZA 4AIGA 4ON1A 1UTTA 5BPAA 3KECA 5CXAA 1OS9A 1GXDA 2YB9A 2DW2A 1XUDA 5I2ZA 1K7IA 1Y0VA 4ZR5A 1PWWA 1HV5A 1CAQA 2MZHA 2MZEA 2QPJA 1ND1A 1EUBA 1S4BP 1JH1A 1PWUA 3F15A 2SRTA 4L19A 1JIZA 1SRPA 4IUWA 4H1QA 1BSWA 3U1RA 1WNIA 1XFUA 1Z3JA 1XFWA 3L0TA 5CUHA 4QKZA 3OHLA 3SHIA 1PWQA 1Y93A 2DDFA 3E8RA 1OO9A 3ZUKA 4JA1A 1QIAA 5D1SA 1BM6A
chains in the Genus database with same CATH superfamily
1HTDA 1Y8JA 3DTEA 2OVXA 4G9LA 2MLRA 4I35A 4CTHA 3WV1A 4HMAA 1JAOA 2WOAA 1B8YA 4PKUA 1XFVA 3LKAA 3L0VA 1OM6A 1MMRA 2DDYA 3LQBA 1R1JA 3AYKA 4A7BA 1BQQM 1JKYA 2A8HA 4DF9A 1BZSA 1GO7P 2W15A 3I7IA 1KUGA 2I47A 2OZRA 2E3XA 2K2GA 1K7QA 2AYKA 2YIGA 1XURA 1AYKA 5D3CA 1D5JA 1GE7A 2J0TA 4GWMA 2OI0A 3GBOA 1MMQA 3DSLA 1R1HA 3B2ZA 4PKVA 2W12A 3RTSA 2X7MA 4XM8A 1G49A 1USNA 4R3VA 4L6TA 1GE6A 1KBCA 1R55A 1QJIA 4Q1LA 4AYKA 2W13A 1CGFA 4L63A 2FV5A 1GO8P 2JSDA 2JIHA 4WK7A 1BUVM 1ATLA 3TSKA 2X3BA 2E2DA 2USNA 3KRYA 4GWNA 1EB6A 1I1IP 3HDAP 1XUCA 2L0RA 4GR0A 4I03A 2V4BA 2RJQA 3LQ0A 3O64A 1PWVA 3HBVP 5B5OA 2O3EA 3DPEA 3AIGA 2X3AA 1GKDA 4DPEA 4GUYA 1FM1A 1R1IA 4EFSA 2JT5A 5JMYA 5I43A 2CLTA 2POJA 3DWBA 1CGLA 1QICA 1KUHA 3VI1A 3HY7A 1A86A 4GQLA 1KUKA 1IADA 2OW9A 3LEAA 5B5PA 1KUFA 3BA0A 3EDGA 2MLSA 5I0LA 1SATA 4GR8A 2OVZA 2Z2DA 4WKIA 3HY9A 3LIKA 1SLMA 1JK3A 1HFSA 2OW2A 4PKRA 1IABA 3CKIA 2OXWA 2W0DA 4FXYP 3EWJA 1ZS0A 5I4OA 4PKSA 3F18A 5D2BA 2JT6A 5D1TA 1H71P 3F16A 1UTZA 1CK7A 1XM5A 1D8FA 830CA 1YQYA 1O0QA 1RMZA 1B3DA 5L79A 3TVCA 2W14A 1IAAA 1OM7A 3F19A 1CIZA 2J83A 2AIGP 3DNGA 2ERQA 5L7FA 3EDHA 4JIJA 1ZXVA 3EHYA 3VTGA 4PKTA 3O2XA 4H30A 3NX7A 2N8RA 4XBHA 1CXVA 2TCLA 4WF6A 3LJGA 3B92A 1PWPA 1FLSA 4PKQA 1IAGA 4H2EA 3P1VA 2K9CA 2OW1A 4G0DA 3LUNA 1HY7A 1HFCA 1RM8A 3LMCA 1A85A 3I7GA 2DW0A 1AF0A 1UMTA 3WV3A 2X3CA 1QJJA 1SU3A 1CQRA 3LJTA 3TT4A 1XFXA 1GKCA 3DTKA 3ELMA 3RTTA 1UEAA 2JNPA 5D7WA 1K7GA 4FU4A 1I76A 4GF1A 1BIWA 1ZXCA 3DPFA 1ZTQA 1ZVXA 1YP1A 1HOVA 3KHIA 1DTHA 1MNCA 2RJPA 1G12A 1O0TA 4H3XA 2CKIA 1C7KA 3DTIA 3HYGA 3TS4A 4WZVA 1SMPA 1QUAA 2MZIA 4IN9A 4XCTA 5I12A 3F1AA 1ROSA 3HBUP 1XAXA 1JANA 1YOUA 3MA2A 4FVLA 1KUIA 1XFYA 1ASTA 2WO9A 5BOYA 4ILWD 2OXZA 4DD8A 4J4MA 1BKCE 1OMJA 3LUMA 2O36A 2Y6CA 1JAPA 4AXQA 1OZ9A 456CA 4AUOA 2PJTA 3P24A 1BKCI 4XM7A 3LGPA 3K7NA 5CZMA 1Q3AA 2FV9A 1QIBA 3Q2HA 3ZXHA 3Q2GA 1DMTA 4DV8A 4XM6A 2OW0A 1KAPP 3K7LA 3HDBA 2XS4A 3USNA 3LE9A 3LK8A 3ZVSA 3UVCA 4H76A 3LILA 1G9KA 3AYUA 1GE5A 4H82A 1BKCA 1ZP5A 1XFZA 4IJOA 3N2UA 1EAKA 4A3WA 4HX3A 1YCMA 2OY4A 3LJZA 3OHOA 3DL1A 4H49A 1D8MA 2HU6A 4JP4A 3V96B 4GR3A 2YUFA 3F17A 966CA 1BQOA 5I3MA 1CGEA 1BUDA 3KMCA 4PKWA 1I73A 1UMSA 1C3IA 5D1UA 4L7AA 1C8TA 2ERPA 4FXQA 3KEKA 3EDIA 4JQGA 2EROA 2XS3A 1JIWP 1JAQA 2KRJA 5BOTA 4JPAA 3N2VA 1L6JA 3B8ZA 1G05A 3KWVC 5H8XA 1D7XA 3LIRA 1MMBA 1MMPA 2D1OA 3EHXA 1SLNA 1FBLA 4WKEA 3KMEA 1OM8A 2OXUA 2DW1A 3G5CA 1J7NA 1JJ9A 1IACA 2Y6DA 1AKLA 1IAEA 4H84A 2D1NA 5LABA 1OS2A 2OY2A 3WV2A 1R54A 3HB2P 3KEJA 3G42A 1G4KA 2WO8A 3EDZA 4AIGA 1TVIA 4ON1A 1UTTA 5BPAA 3KECA 5CXAA 1OS9A 1GXDA 2YB9A 2DW2A 1XUDA 5I2ZA 1K7IA 1Y0VA 4ZR5A 1PWWA 1HV5A 1CAQA 2MZHA 2MZEA 2QPJA 1ND1A 1EUBA 1S4BP 1JH1A 1PWUA 3F15A 2SRTA 4L19A 1JIZA 1SRPA 4IUWA 4H1QA 1BSWA 3U1RA 1WNIA 1XFUA 1Z3JA 1XFWA 3L0TA 5CUHA 4QKZA 3OHLA 3SHIA 1PWQA 1Y93A 2DDFA 3E8RA 1OO9A 3ZUKA 4JA1A 1QIAA 5D1SA 1BM6A
chains in the Genus database with same CATH topology
1HTDA 1Y8JA 3DTEA 2OVXA 4G9LA 2MLRA 4I35A 4CTHA 3WV1A 4HMAA 1JAOA 2WOAA 1B8YA 4PKUA 1XFVA 3LKAA 3L0VA 1OM6A 1MMRA 2DDYA 3LQBA 1R1JA 3AYKA 4A7BA 1BQQM 1JKYA 2A8HA 4DF9A 1BZSA 1GO7P 2W15A 3I7IA 1KUGA 2I47A 2OZRA 2E3XA 2K2GA 1K7QA 2AYKA 2YIGA 1XURA 1AYKA 5D3CA 1D5JA 1GE7A 2J0TA 4GWMA 2OI0A 3GBOA 1MMQA 3DSLA 1R1HA 3B2ZA 4PKVA 2W12A 3RTSA 2X7MA 4XM8A 1G49A 1USNA 4R3VA 4L6TA 1GE6A 1KBCA 1R55A 1QJIA 4Q1LA 4AYKA 2W13A 1CGFA 4L63A 2FV5A 1GO8P 2JSDA 2JIHA 4WK7A 1BUVM 1ATLA 3TSKA 2X3BA 2E2DA 2USNA 3KRYA 4GWNA 1EB6A 1I1IP 3HDAP 1XUCA 2L0RA 4GR0A 4I03A 2V4BA 2RJQA 3LQ0A 3O64A 1PWVA 3HBVP 5B5OA 2O3EA 3DPEA 3AIGA 2X3AA 1GKDA 4DPEA 4GUYA 1FM1A 1R1IA 4EFSA 2JT5A 5JMYA 5I43A 2CLTA 2POJA 3DWBA 1CGLA 1QICA 1KUHA 3VI1A 3HY7A 1A86A 4GQLA 1KUKA 1IADA 2OW9A 3LEAA 5B5PA 1KUFA 3BA0A 3EDGA 2MLSA 5I0LA 1SATA 4GR8A 2OVZA 2Z2DA 4WKIA 3HY9A 3LIKA 1SLMA 1JK3A 1HFSA 2OW2A 4PKRA 1IABA 3CKIA 2OXWA 2W0DA 4FXYP 3EWJA 1ZS0A 5I4OA 4PKSA 3F18A 5D2BA 2JT6A 5D1TA 1H71P 3F16A 1UTZA 1CK7A 1D8FA 830CA 1YQYA 1O0QA 1RMZA 1B3DA 5L79A 3TVCA 2W14A 1IAAA 1OM7A 3F19A 1CIZA 2J83A 2AIGP 3DNGA 2ERQA 5L7FA 3EDHA 4JIJA 1ZXVA 3EHYA 3VTGA 4PKTA 3O2XA 4H30A 3NX7A 2N8RA 4XBHA 1CXVA 2TCLA 4WF6A 3LJGA 3B92A 1PWPA 1FLSA 4PKQA 1IAGA 4H2EA 3P1VA 2K9CA 2OW1A 4G0DA 3LUNA 1HY7A 1HFCA 1RM8A 3LMCA 1A85A 3I7GA 2DW0A 1AF0A 1UMTA 3WV3A 2X3CA 1QJJA 1SU3A 1CQRA 3LJTA 3TT4A 1XFXA 1GKCA 3DTKA 3ELMA 3RTTA 1UEAA 2JNPA 5D7WA 1K7GA 4FU4A 1I76A 4GF1A 1BIWA 1ZXCA 3DPFA 1ZTQA 1ZVXA 1YP1A 1HOVA 3KHIA 1DTHA 1MNCA 2RJPA 1G12A 1O0TA 4H3XA 2CKIA 1C7KA 3DTIA 3HYGA 3TS4A 4WZVA 1SMPA 1QUAA 2MZIA 4IN9A 4XCTA 5I12A 3F1AA 1ROSA 3HBUP 1JANA 1YOUA 3MA2A 4FVLA 1KUIA 1XFYA 1ASTA 2WO9A 5BOYA 4ILWD 2OXZA 4DD8A 4J4MA 1BKCE 1OMJA 3LUMA 2O36A 2Y6CA 1JAPA 4AXQA 456CA 4AUOA 2PJTA 3P24A 1BKCI 4XM7A 3LGPA 3K7NA 5CZMA 1Q3AA 2FV9A 1QIBA 3Q2HA 3ZXHA 3Q2GA 1DMTA 4DV8A 4XM6A 2OW0A 1KAPP 3K7LA 3HDBA 2XS4A 3USNA 3LE9A 3LK8A 3ZVSA 3UVCA 4H76A 3LILA 1G9KA 3AYUA 1GE5A 4H82A 1BKCA 1ZP5A 1XFZA 4IJOA 3N2UA 1EAKA 4A3WA 4HX3A 1YCMA 2OY4A 3LJZA 3OHOA 3DL1A 4H49A 1D8MA 2HU6A 4JP4A 3V96B 4GR3A 2YUFA 3F17A 966CA 1BQOA 5I3MA 1CGEA 1BUDA 3KMCA 4PKWA 1I73A 1UMSA 1C3IA 5D1UA 4L7AA 1C8TA 2ERPA 4FXQA 3KEKA 3EDIA 4JQGA 2EROA 2XS3A 1JIWP 1JAQA 2KRJA 5BOTA 4JPAA 3N2VA 1L6JA 3B8ZA 1G05A 3KWVC 5H8XA 1D7XA 3LIRA 1MMBA 1MMPA 2D1OA 3EHXA 1SLNA 1FBLA 4WKEA 3KMEA 1OM8A 2OXUA 2DW1A 3G5CA 1J7NA 1JJ9A 1IACA 2Y6DA 1AKLA 1IAEA 4H84A 2D1NA 5LABA 1OS2A 2OY2A 3WV2A 1R54A 3HB2P 3KEJA 3G42A 1G4KA 2WO8A 3EDZA 4AIGA 4ON1A 1UTTA 5BPAA 3KECA 5CXAA 1OS9A 1GXDA 2YB9A 2DW2A 1XUDA 5I2ZA 1K7IA 1Y0VA 4ZR5A 1PWWA 1HV5A 1CAQA 2MZHA 2MZEA 2QPJA 1ND1A 1EUBA 1S4BP 1JH1A 1PWUA 3F15A 2SRTA 4L19A 1JIZA 1SRPA 4IUWA 4H1QA 1BSWA 3U1RA 1WNIA 1XFUA 1Z3JA 1XFWA 3L0TA 5CUHA 4QKZA 3OHLA 3SHIA 1PWQA 1Y93A 2DDFA 3E8RA 1OO9A 3ZUKA 4JA1A 1QIAA 5D1SA 1BM6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HTD A;  1Y8J A;  2OVX A;  4G9L A;  2MLR A;  4I35 A;  4CTH A;  3WV1 A;  4HMA A;  1JAO A;  2WOA A;  1B8Y A;  4PKU A;  1XFV A;  3LKA A;  3L0V A;  1OM6 A;  1MMR A;  2DDY A;  3LQB A;  1R1J A;  3AYK A;  4A7B A;  1BQQ M;  1JKY A;  2A8H A;  4DF9 A;  1BZS A;  1GO7 P;  2W15 A;  3I7I A;  1KUG A;  2I47 A;  2OZR A;  2E3X A;  2K2G A;  1K7Q A;  2AYK A;  2YIG A;  1XUR A;  1AYK A;  5D3C A;  1D5J A;  1GE7 A;  2J0T A;  4GWM A;  2OI0 A;  3GBO A;  1MMQ A;  3DSL A;  1R1H A;  3B2Z A;  4PKV A;  2W12 A;  3RTS A;  2X7M A;  4XM8 A;  1G49 A;  1USN A;  4R3V A;  4L6T A;  1GE6 A;  1KBC A;  1R55 A;  1QJI A;  4Q1L A;  4AYK A;  2W13 A;  1CGF A;  4L63 A;  2FV5 A;  1GO8 P;  2JSD A;  2JIH A;  4WK7 A;  1BUV M;  1ATL A;  3TSK A;  2X3B A;  2E2D A;  2USN A;  3KRY A;  4GWN A;  1EB6 A;  1I1I P;  3HDA P;  1XUC A;  2L0R A;  4GR0 A;  4I03 A;  2V4B A;  2RJQ A;  3LQ0 A;  3O64 A;  1PWV A;  3HBV P;  5B5O A;  2O3E A;  3DPE A;  3AIG A;  2X3A A;  1GKD A;  4DPE A;  4GUY A;  1FM1 A;  1R1I A;  4EFS A;  2JT5 A;  5JMY A;  5I43 A;  2CLT A;  2POJ A;  3DWB A;  1CGL A;  1QIC A;  1KUH A;  3VI1 A;  3HY7 A;  1A86 A;  4GQL A;  1KUK A;  1IAD A;  2OW9 A;  3LEA A;  5B5P A;  1KUF A;  3BA0 A;  3EDG A;  2MLS A;  5I0L A;  1SAT A;  4GR8 A;  2OVZ A;  2Z2D A;  4WKI A;  3HY9 A;  3LIK A;  1SLM A;  1JK3 A;  1HFS A;  2OW2 A;  4PKR A;  1IAB A;  3CKI A;  2OXW A;  2W0D A;  4FXY P;  3EWJ A;  1ZS0 A;  5I4O A;  4PKS A;  3F18 A;  5D2B A;  2JT6 A;  5D1T A;  1H71 P;  3F16 A;  1UTZ A;  1CK7 A;  1D8F A;  830C A;  1YQY A;  1O0Q A;  1RMZ A;  1B3D A;  5L79 A;  3TVC A;  2W14 A;  1IAA A;  1OM7 A;  3F19 A;  1CIZ A;  2J83 A;  2AIG P;  3DNG A;  2ERQ A;  5L7F A;  3EDH A;  4JIJ A;  1ZXV A;  3EHY A;  3VTG A;  4PKT A;  3O2X A;  4H30 A;  3NX7 A;  2N8R A;  4XBH A;  1CXV A;  2TCL A;  4WF6 A;  3LJG A;  3B92 A;  1PWP A;  1FLS A;  4PKQ A;  1IAG A;  4H2E A;  3P1V A;  2K9C A;  2OW1 A;  4G0D A;  3LUN A;  1HY7 A;  1HFC A;  1RM8 A;  3LMC A;  1A85 A;  3I7G A;  2DW0 A;  1AF0 A;  1UMT A;  3WV3 A;  2X3C A;  1QJJ A;  1SU3 A;  1CQR A;  3LJT A;  3TT4 A;  1XFX A;  1GKC A;  3ELM A;  3RTT A;  1UEA A;  2JNP A;  5D7W A;  1K7G A;  4FU4 A;  1I76 A;  4GF1 A;  1BIW A;  1ZXC A;  3DPF A;  1ZTQ A;  1ZVX A;  1YP1 A;  1HOV A;  3KHI A;  1DTH A;  1MNC A;  2RJP A;  1G12 A;  1O0T A;  4H3X A;  2CKI A;  1C7K A;  3HYG A;  3TS4 A;  4WZV A;  1SMP A;  1QUA A;  2MZI A;  4IN9 A;  4XCT A;  5I12 A;  3F1A A;  1ROS A;  3HBU P;  1JAN A;  1YOU A;  3MA2 A;  4FVL A;  1KUI A;  1XFY A;  1AST A;  2WO9 A;  5BOY A;  4ILW D;  2OXZ A;  4DD8 A;  4J4M A;  1BKC E;  1OMJ A;  3LUM A;  2O36 A;  2Y6C A;  1JAP A;  4AXQ A;  456C A;  4AUO A;  2PJT A;  3P24 A;  1BKC I;  4XM7 A;  3LGP A;  3K7N A;  5CZM A;  1Q3A A;  2FV9 A;  1QIB A;  3Q2H A;  3ZXH A;  3Q2G A;  1DMT A;  4DV8 A;  4XM6 A;  2OW0 A;  1KAP P;  3K7L A;  3HDB A;  2XS4 A;  3USN A;  3LE9 A;  3LK8 A;  3ZVS A;  3UVC A;  4H76 A;  3LIL A;  1G9K A;  3AYU A;  1GE5 A;  4H82 A;  1BKC A;  1ZP5 A;  1XFZ A;  4IJO A;  3N2U A;  1EAK A;  4A3W A;  4HX3 A;  1YCM A;  2OY4 A;  3LJZ A;  3OHO A;  3DL1 A;  4H49 A;  1D8M A;  2HU6 A;  4JP4 A;  3V96 B;  4GR3 A;  3F17 A;  966C A;  1BQO A;  5I3M A;  1CGE A;  1BUD A;  3KMC A;  4PKW A;  1I73 A;  1UMS A;  1C3I A;  5D1U A;  1C8T A;  2ERP A;  4FXQ A;  3KEK A;  3EDI A;  4JQG A;  2ERO A;  2XS3 A;  1JIW P;  1JAQ A;  2KRJ A;  5BOT A;  4JPA A;  3N2V A;  1L6J A;  3B8Z A;  1G05 A;  3KWV C;  5H8X A;  1D7X A;  3LIR A;  1MMB A;  1MMP A;  2D1O A;  3EHX A;  1SLN A;  1FBL A;  4WKE A;  3KME A;  1OM8 A;  2OXU A;  2DW1 A;  3G5C A;  1J7N A;  1JJ9 A;  1IAC A;  2Y6D A;  1AKL A;  1IAE A;  4H84 A;  2D1N A;  5LAB A;  1OS2 A;  2OY2 A;  3WV2 A;  1R54 A;  3HB2 P;  3KEJ A;  3G42 A;  1G4K A;  2WO8 A;  3EDZ A;  4AIG A;  4ON1 A;  1UTT A;  5BPA A;  3KEC A;  5CXA A;  1OS9 A;  1GXD A;  2YB9 A;  2DW2 A;  1XUD A;  5I2Z A;  1K7I A;  1Y0V A;  4ZR5 A;  1PWW A;  1HV5 A;  1CAQ A;  2MZH A;  2MZE A;  2QPJ A;  1ND1 A;  1EUB A;  1S4B P;  1JH1 A;  1PWU A;  3F15 A;  2SRT A;  4L19 A;  1JIZ A;  1SRP A;  4IUW A;  4H1Q A;  1BSW A;  3U1R A;  1WNI A;  1XFU A;  1Z3J A;  1XFW A;  3L0T A;  5CUH A;  4QKZ A;  3OHL A;  3SHI A;  1PWQ A;  1Y93 A;  2DDF A;  3E8R A;  1OO9 A;  3ZUK A;  4JA1 A;  1QIA A;  5D1S A;  1BM6 A; 
#chains in the Genus database with same CATH topology
 1HTD A;  1Y8J A;  3DTE A;  2OVX A;  4G9L A;  2MLR A;  4I35 A;  4CTH A;  3WV1 A;  4HMA A;  1JAO A;  2WOA A;  1B8Y A;  4PKU A;  1XFV A;  3LKA A;  3L0V A;  1OM6 A;  1MMR A;  2DDY A;  3LQB A;  1R1J A;  3AYK A;  4A7B A;  1BQQ M;  1JKY A;  2A8H A;  4DF9 A;  1BZS A;  1GO7 P;  2W15 A;  3I7I A;  1KUG A;  2I47 A;  2OZR A;  2E3X A;  2K2G A;  1K7Q A;  2AYK A;  2YIG A;  1XUR A;  1AYK A;  5D3C A;  1D5J A;  1GE7 A;  2J0T A;  4GWM A;  2OI0 A;  3GBO A;  1MMQ A;  3DSL A;  1R1H A;  3B2Z A;  4PKV A;  2W12 A;  3RTS A;  2X7M A;  4XM8 A;  1G49 A;  1USN A;  4R3V A;  4L6T A;  1GE6 A;  1KBC A;  1R55 A;  1QJI A;  4Q1L A;  4AYK A;  2W13 A;  1CGF A;  4L63 A;  2FV5 A;  1GO8 P;  2JSD A;  2JIH A;  4WK7 A;  1BUV M;  1ATL A;  3TSK A;  2X3B A;  2E2D A;  2USN A;  3KRY A;  4GWN A;  1EB6 A;  1I1I P;  3HDA P;  1XUC A;  2L0R A;  4GR0 A;  4I03 A;  2V4B A;  2RJQ A;  3LQ0 A;  3O64 A;  1PWV A;  3HBV P;  5B5O A;  2O3E A;  3DPE A;  3AIG A;  2X3A A;  1GKD A;  4DPE A;  4GUY A;  1FM1 A;  1R1I A;  4EFS A;  2JT5 A;  5JMY A;  5I43 A;  2CLT A;  2POJ A;  3DWB A;  1CGL A;  1QIC A;  1KUH A;  3VI1 A;  3HY7 A;  1A86 A;  4GQL A;  1KUK A;  1IAD A;  2OW9 A;  3LEA A;  5B5P A;  1KUF A;  3BA0 A;  3EDG A;  2MLS A;  5I0L A;  1SAT A;  4GR8 A;  2OVZ A;  2Z2D A;  4WKI A;  3HY9 A;  3LIK A;  1SLM A;  1JK3 A;  1HFS A;  2OW2 A;  4PKR A;  1IAB A;  3CKI A;  2OXW A;  2W0D A;  4FXY P;  3EWJ A;  1ZS0 A;  5I4O A;  4PKS A;  3F18 A;  5D2B A;  2JT6 A;  5D1T A;  1H71 P;  3F16 A;  1UTZ A;  1CK7 A;  1XM5 A;  1D8F A;  830C A;  1YQY A;  1O0Q A;  1RMZ A;  1B3D A;  5L79 A;  3TVC A;  2W14 A;  1IAA A;  1OM7 A;  3F19 A;  1CIZ A;  2J83 A;  2AIG P;  3DNG A;  2ERQ A;  5L7F A;  3EDH A;  4JIJ A;  1ZXV A;  3EHY A;  3VTG A;  4PKT A;  3O2X A;  4H30 A;  3NX7 A;  2N8R A;  4XBH A;  1CXV A;  2TCL A;  4WF6 A;  3LJG A;  3B92 A;  1PWP A;  1FLS A;  4PKQ A;  1IAG A;  4H2E A;  3P1V A;  2K9C A;  2OW1 A;  4G0D A;  3LUN A;  1HY7 A;  1HFC A;  1RM8 A;  3LMC A;  1A85 A;  3I7G A;  2DW0 A;  1AF0 A;  1UMT A;  3WV3 A;  2X3C A;  1QJJ A;  1SU3 A;  1CQR A;  3LJT A;  3TT4 A;  1XFX A;  1GKC A;  3DTK A;  3ELM A;  3RTT A;  1UEA A;  2JNP A;  5D7W A;  1K7G A;  4FU4 A;  1I76 A;  4GF1 A;  1BIW A;  1ZXC A;  3DPF A;  1ZTQ A;  1ZVX A;  1YP1 A;  1HOV A;  3KHI A;  1DTH A;  1MNC A;  2RJP A;  1G12 A;  1O0T A;  4H3X A;  2CKI A;  1C7K A;  3DTI A;  3HYG A;  3TS4 A;  4WZV A;  1SMP A;  1QUA A;  2MZI A;  4IN9 A;  4XCT A;  5I12 A;  3F1A A;  1ROS A;  3HBU P;  1XAX A;  1JAN A;  1YOU A;  3MA2 A;  4FVL A;  1KUI A;  1XFY A;  1AST A;  2WO9 A;  5BOY A;  4ILW D;  2OXZ A;  4DD8 A;  4J4M A;  1BKC E;  1OMJ A;  3LUM A;  2O36 A;  2Y6C A;  1JAP A;  4AXQ A;  1OZ9 A;  456C A;  4AUO A;  2PJT A;  3P24 A;  1BKC I;  4XM7 A;  3LGP A;  3K7N A;  5CZM A;  1Q3A A;  2FV9 A;  1QIB A;  3Q2H A;  3ZXH A;  3Q2G A;  1DMT A;  4DV8 A;  4XM6 A;  2OW0 A;  1KAP P;  3K7L A;  3HDB A;  2XS4 A;  3USN A;  3LE9 A;  3LK8 A;  3ZVS A;  3UVC A;  4H76 A;  3LIL A;  1G9K A;  3AYU A;  1GE5 A;  4H82 A;  1BKC A;  1ZP5 A;  1XFZ A;  4IJO A;  3N2U A;  1EAK A;  4A3W A;  4HX3 A;  1YCM A;  2OY4 A;  3LJZ A;  3OHO A;  3DL1 A;  4H49 A;  1D8M A;  2HU6 A;  4JP4 A;  3V96 B;  4GR3 A;  2YUF A;  3F17 A;  966C A;  1BQO A;  5I3M A;  1CGE A;  1BUD A;  3KMC A;  4PKW A;  1I73 A;  1UMS A;  1C3I A;  5D1U A;  4L7A A;  1C8T A;  2ERP A;  4FXQ A;  3KEK A;  3EDI A;  4JQG A;  2ERO A;  2XS3 A;  1JIW P;  1JAQ A;  2KRJ A;  5BOT A;  4JPA A;  3N2V A;  1L6J A;  3B8Z A;  1G05 A;  3KWV C;  5H8X A;  1D7X A;  3LIR A;  1MMB A;  1MMP A;  2D1O A;  3EHX A;  1SLN A;  1FBL A;  4WKE A;  3KME A;  1OM8 A;  2OXU A;  2DW1 A;  3G5C A;  1J7N A;  1JJ9 A;  1IAC A;  2Y6D A;  1AKL A;  1IAE A;  4H84 A;  2D1N A;  5LAB A;  1OS2 A;  2OY2 A;  3WV2 A;  1R54 A;  3HB2 P;  3KEJ A;  3G42 A;  1G4K A;  2WO8 A;  3EDZ A;  4AIG A;  1TVI A;  4ON1 A;  1UTT A;  5BPA A;  3KEC A;  5CXA A;  1OS9 A;  1GXD A;  2YB9 A;  2DW2 A;  1XUD A;  5I2Z A;  1K7I A;  1Y0V A;  4ZR5 A;  1PWW A;  1HV5 A;  1CAQ A;  2MZH A;  2MZE A;  2QPJ A;  1ND1 A;  1EUB A;  1S4B P;  1JH1 A;  1PWU A;  3F15 A;  2SRT A;  4L19 A;  1JIZ A;  1SRP A;  4IUW A;  4H1Q A;  1BSW A;  3U1R A;  1WNI A;  1XFU A;  1Z3J A;  1XFW A;  3L0T A;  5CUH A;  4QKZ A;  3OHL A;  3SHI A;  1PWQ A;  1Y93 A;  2DDF A;  3E8R A;  1OO9 A;  3ZUK A;  4JA1 A;  1QIA A;  5D1S A;  1BM6 A; 
#chains in the Genus database with same CATH homology
 1HTD A;  1Y8J A;  3DTE A;  2OVX A;  4G9L A;  2MLR A;  4I35 A;  4CTH A;  3WV1 A;  4HMA A;  1JAO A;  2WOA A;  1B8Y A;  4PKU A;  1XFV A;  3LKA A;  3L0V A;  1OM6 A;  1MMR A;  2DDY A;  3LQB A;  1R1J A;  3AYK A;  4A7B A;  1BQQ M;  1JKY A;  2A8H A;  4DF9 A;  1BZS A;  1GO7 P;  2W15 A;  3I7I A;  1KUG A;  2I47 A;  2OZR A;  2E3X A;  2K2G A;  1K7Q A;  2AYK A;  2YIG A;  1XUR A;  1AYK A;  5D3C A;  1D5J A;  1GE7 A;  2J0T A;  4GWM A;  2OI0 A;  3GBO A;  1MMQ A;  3DSL A;  1R1H A;  3B2Z A;  4PKV A;  2W12 A;  3RTS A;  2X7M A;  4XM8 A;  1G49 A;  1USN A;  4R3V A;  4L6T A;  1GE6 A;  1KBC A;  1R55 A;  1QJI A;  4Q1L A;  4AYK A;  2W13 A;  1CGF A;  4L63 A;  2FV5 A;  1GO8 P;  2JSD A;  2JIH A;  4WK7 A;  1BUV M;  1ATL A;  3TSK A;  2X3B A;  2E2D A;  2USN A;  3KRY A;  4GWN A;  1EB6 A;  1I1I P;  3HDA P;  1XUC A;  2L0R A;  4GR0 A;  4I03 A;  2V4B A;  2RJQ A;  3LQ0 A;  3O64 A;  1PWV A;  3HBV P;  5B5O A;  2O3E A;  3DPE A;  3AIG A;  2X3A A;  1GKD A;  4DPE A;  4GUY A;  1FM1 A;  1R1I A;  4EFS A;  2JT5 A;  5JMY A;  5I43 A;  2CLT A;  2POJ A;  3DWB A;  1CGL A;  1QIC A;  1KUH A;  3VI1 A;  3HY7 A;  1A86 A;  4GQL A;  1KUK A;  1IAD A;  2OW9 A;  3LEA A;  5B5P A;  1KUF A;  3BA0 A;  3EDG A;  2MLS A;  5I0L A;  1SAT A;  4GR8 A;  2OVZ A;  2Z2D A;  4WKI A;  3HY9 A;  3LIK A;  1SLM A;  1JK3 A;  1HFS A;  2OW2 A;  4PKR A;  1IAB A;  3CKI A;  2OXW A;  2W0D A;  4FXY P;  3EWJ A;  1ZS0 A;  5I4O A;  4PKS A;  3F18 A;  5D2B A;  2JT6 A;  5D1T A;  1H71 P;  3F16 A;  1UTZ A;  1CK7 A;  1D8F A;  830C A;  1YQY A;  1O0Q A;  1RMZ A;  1B3D A;  5L79 A;  3TVC A;  2W14 A;  1IAA A;  1OM7 A;  3F19 A;  1CIZ A;  2J83 A;  2AIG P;  3DNG A;  2ERQ A;  5L7F A;  3EDH A;  4JIJ A;  1ZXV A;  3EHY A;  3VTG A;  4PKT A;  3O2X A;  4H30 A;  3NX7 A;  2N8R A;  4XBH A;  1CXV A;  2TCL A;  4WF6 A;  3LJG A;  3B92 A;  1PWP A;  1FLS A;  4PKQ A;  1IAG A;  4H2E A;  3P1V A;  2K9C A;  2OW1 A;  4G0D A;  3LUN A;  1HY7 A;  1HFC A;  1RM8 A;  3LMC A;  1A85 A;  3I7G A;  2DW0 A;  1AF0 A;  1UMT A;  3WV3 A;  2X3C A;  1QJJ A;  1SU3 A;  1CQR A;  3LJT A;  3TT4 A;  1XFX A;  1GKC A;  3DTK A;  3ELM A;  3RTT A;  1UEA A;  2JNP A;  5D7W A;  1K7G A;  4FU4 A;  1I76 A;  4GF1 A;  1BIW A;  1ZXC A;  3DPF A;  1ZTQ A;  1ZVX A;  1YP1 A;  1HOV A;  3KHI A;  1DTH A;  1MNC A;  2RJP A;  1G12 A;  1O0T A;  4H3X A;  2CKI A;  1C7K A;  3DTI A;  3HYG A;  3TS4 A;  4WZV A;  1SMP A;  1QUA A;  2MZI A;  4IN9 A;  4XCT A;  5I12 A;  3F1A A;  1ROS A;  3HBU P;  1JAN A;  1YOU A;  3MA2 A;  4FVL A;  1KUI A;  1XFY A;  1AST A;  2WO9 A;  5BOY A;  4ILW D;  2OXZ A;  4DD8 A;  4J4M A;  1BKC E;  1OMJ A;  3LUM A;  2O36 A;  2Y6C A;  1JAP A;  4AXQ A;  456C A;  4AUO A;  2PJT A;  3P24 A;  1BKC I;  4XM7 A;  3LGP A;  3K7N A;  5CZM A;  1Q3A A;  2FV9 A;  1QIB A;  3Q2H A;  3ZXH A;  3Q2G A;  1DMT A;  4DV8 A;  4XM6 A;  2OW0 A;  1KAP P;  3K7L A;  3HDB A;  2XS4 A;  3USN A;  3LE9 A;  3LK8 A;  3ZVS A;  3UVC A;  4H76 A;  3LIL A;  1G9K A;  3AYU A;  1GE5 A;  4H82 A;  1BKC A;  1ZP5 A;  1XFZ A;  4IJO A;  3N2U A;  1EAK A;  4A3W A;  4HX3 A;  1YCM A;  2OY4 A;  3LJZ A;  3OHO A;  3DL1 A;  4H49 A;  1D8M A;  2HU6 A;  4JP4 A;  3V96 B;  4GR3 A;  2YUF A;  3F17 A;  966C A;  1BQO A;  5I3M A;  1CGE A;  1BUD A;  3KMC A;  4PKW A;  1I73 A;  1UMS A;  1C3I A;  5D1U A;  4L7A A;  1C8T A;  2ERP A;  4FXQ A;  3KEK A;  3EDI A;  4JQG A;  2ERO A;  2XS3 A;  1JIW P;  1JAQ A;  2KRJ A;  5BOT A;  4JPA A;  3N2V A;  1L6J A;  3B8Z A;  1G05 A;  3KWV C;  5H8X A;  1D7X A;  3LIR A;  1MMB A;  1MMP A;  2D1O A;  3EHX A;  1SLN A;  1FBL A;  4WKE A;  3KME A;  1OM8 A;  2OXU A;  2DW1 A;  3G5C A;  1J7N A;  1JJ9 A;  1IAC A;  2Y6D A;  1AKL A;  1IAE A;  4H84 A;  2D1N A;  5LAB A;  1OS2 A;  2OY2 A;  3WV2 A;  1R54 A;  3HB2 P;  3KEJ A;  3G42 A;  1G4K A;  2WO8 A;  3EDZ A;  4AIG A;  4ON1 A;  1UTT A;  5BPA A;  3KEC A;  5CXA A;  1OS9 A;  1GXD A;  2YB9 A;  2DW2 A;  1XUD A;  5I2Z A;  1K7I A;  1Y0V A;  4ZR5 A;  1PWW A;  1HV5 A;  1CAQ A;  2MZH A;  2MZE A;  2QPJ A;  1ND1 A;  1EUB A;  1S4B P;  1JH1 A;  1PWU A;  3F15 A;  2SRT A;  4L19 A;  1JIZ A;  1SRP A;  4IUW A;  4H1Q A;  1BSW A;  3U1R A;  1WNI A;  1XFU A;  1Z3J A;  1XFW A;  3L0T A;  5CUH A;  4QKZ A;  3OHL A;  3SHI A;  1PWQ A;  1Y93 A;  2DDF A;  3E8R A;  1OO9 A;  3ZUK A;  4JA1 A;  1QIA A;  5D1S A;  1BM6 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...