5D2BA

Crystal structure of a mutated catalytic domain of human mmp12 in complex with an hydroxamate analogue of rxp470
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
159
structure length
159
Chain Sequence
MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Zinc-Metalloproteinase Inhibitors: Evaluation of the Complex Role Played by the Zinc-Binding Group on Potency and Selectivity.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 44
structure length 159
sequence length 159
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2015-08-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 5d2bA00
3SHIA 3V96B 1Z3JA 1EUBA 1Y93A 2E2DA 3G42A 4QKZA 1PWVA 2CLTA 1QJJA 1MMBA 1XFYA 1HFSA 4L6TA 1R54A 3LUMA 1Y8JA 4XCTA 4JA1A 3AIGA 3KHIA 4JQGA 4WF6A 2OVXA 5I12A 1L6JA 1ZP5A 4G9LA 1QICA 1BKCI 1PWPA 1ZXCA 2EROA 1R55A 1SATA 4EFSA 4AYKA 4H49A 3P1VA 3LIRA 1BKCA 1G05A 1KBCA 5I43A 3F1AA 4H3XA 2L0RA 1BSWA 4DV8A 3TSKA 1JKYA 1BQQM 3DPFA 2MZIA 3HYGA 3BA0A 4HMAA 3WV1A 3ELMA 2PJTA 4GF1A 1G12A 1XFXA 1GE5A 2XS4A 4IN9A 3KMCA 1KAPP 1HFCA 5H8XA 1RMZA 3HY7A 4H76A 1PWWA 1WNIA 2E3XA 1CQRA 1ND1A 5CZMA 1JH1A 4GWNA 2OY2A 1YCMA 3OHLA 3LJTA 4FXQA 4L63A 5I2ZA 4Q1LA 4CTHA 1OS9A 4AUOA 3KEJA 1CGFA 1C8TA 1QIBA 2V4BA 4AXQA 2DW2A 3NX7A 1UTZA 3EHXA 1R1HA 4A3WA 2JSDA 1PWUA 2RJPA 3P24A 2CKIA 2XS3A 2WO8A 1D7XA 4ZR5A 3UVCA 4DPEA 1MMQA 4H30A 1MMRA 3RTTA 2K9CA 2OXWA 3LKAA 1XFWA 1R1IA 4PKQA 5BOTA 1CK7A 1GE7A 1HOVA 1OM8A 3CKIA 3LE9A 1AYKA 3HBVP 3WV3A 3F17A 3TS4A 1UEAA 2X3BA 1S4BP 2MZEA 4AIGA 5BOYA 2HU6A 1CGEA 1BQOA 2POJA 2I47A 2X3CA 1UMTA 3HY9A 1G4KA 5D7WA 2JT5A 3VI1A 1D8MA 966CA 3LEAA 2W0DA 3KRYA 3B2ZA 3ZVSA 4JP4A 5D1TA 1JANA 1OM6A 5I0LA 1QUAA 2OI0A 1OS2A 1KUHA 2JIHA 2SRTA 2W12A 3AYUA 1MMPA 1C3IA 4GQLA 1B8YA 1C7KA 1KUKA 3F15A 1K7QA 1G9KA 3LQBA 2OXUA 3I7GA 2JT6A 1KUIA 3MA2A 3KMEA 1KUGA 1MNCA 2ERPA 1IADA 2WO9A 4XM7A 4A7BA 2KRJA 4JPAA 1JIZA 4HX3A 2MLSA 1B3DA 3EDZA 3WV2A 3K7LA 5CXAA 2AYKA 2W14A 5D2BA 1QIAA 3OHOA 2D1NA 5B5OA 3Q2GA 1JJ9A 5D1SA 1XFVA 1EAKA 4J4MA 3F18A 1ZS0A 2QPJA 2W15A 5I4OA 4DF9A 1GO8P 2N8RA 5D3CA 1Y0VA 2DDYA 2USNA 1A85A 1BZSA 1IABA 830CA 5B5PA 4WKIA 4WK7A 1IAEA 4PKUA 2ERQA 4I35A 2WOAA 4FXYP 2OZRA 5JMYA 1UTTA 3LILA 4ILWD 5BPAA 3DL1A 1YP1A 4IUWA 3HDBA 1CXVA 1SU3A 4PKWA 1CAQA 4H1QA 4WKEA 2MZHA 2OW0A 1JK3A 3LJZA 4XM8A 3LJGA 2X3AA 2FV5A 456CA 2W13A 4G0DA 3TT4A 1USNA 1GE6A 4GWMA 4IJOA 1ASTA 1QJIA 1JAPA 1ROSA 1GXDA 1FBLA 2O36A 1H71P 3LK8A 4R3VA 1XUCA 2K2GA 2D1OA 3DPEA 1J7NA 4H84A 1D8FA 2TCLA 3LQ0A 3KEKA 1BIWA 4FU4A 2Y6DA 1HV5A 1XFZA 1SRPA 5I3MA 1K7IA 3LMCA 2OVZA 3K7NA 1D5JA 3DSLA 5L79A 2O3EA 1GKCA 3EHYA 5D1UA 1XURA 1PWQA 3LIKA 1JAQA 1YOUA 4L19A 1ATLA 1JAOA 1OMJA 3LUNA 3F16A 3HB2P 2OXZA 1FM1A 3B8ZA 2OW2A 1BUVM 2OY4A 1ZVXA 3KECA 1DMTA 4FVLA 2A8HA 3EDIA 3USNA 1GKDA 3LGPA 1IAAA 1OM7A 4ON1A 3GBOA 1EB6A 4PKRA 1CIZA 1IACA 4PKTA 3I7IA 1A86A 1AF0A 2J83A 2YB9A 1K7GA 2J0TA 1XUDA 4WZVA 1BKCE 4GUYA 3HBUP 3RTSA 1BUDA 1HY7A 4PKSA 4DD8A 3EWJA 3G5CA 4PKVA 2JNPA 3L0TA 3TVCA 2Z2DA 1AKLA 1GO7P 2FV9A 2X7MA 2Y6CA 1KUFA 3U1RA 4I03A 4H2EA 3KWVC 3N2VA 1I1IP 3ZXHA 2OW1A 1SLNA 1BM6A 1HTDA 2DW0A 1O0QA 3E8RA 5CUHA 2DW1A 2RJQA 1SMPA 4XM6A 1UMSA 2MLRA 3DWBA 1G49A 1O0TA 3O64A 2DDFA 1RM8A 4GR8A 2AIGP 4H82A 4GR3A 2YIGA 1SLMA 3N2UA 3B92A 3O2XA 1ZTQA 1IAGA 1JIWP 1Q3AA 1YQYA 4XBHA 2OW9A 3DNGA 3EDGA 1I76A 1R1JA 1CGLA 1OO9A 3AYKA 3Q2HA 3F19A 1DTHA 1ZXVA 4JIJA 3EDHA 5LABA 4GR0A 3HDAP 1XFUA 1I73A 3L0VA 3VTGA 5L7FA 1FLSA 3ZUKA
chains in the Genus database with same CATH superfamily
3SHIA 3V96B 1Z3JA 1EUBA 1Y93A 2E2DA 3G42A 4QKZA 1PWVA 2CLTA 1QJJA 1MMBA 1XFYA 1HFSA 4L6TA 1R54A 3LUMA 1Y8JA 4XCTA 4JA1A 3AIGA 3KHIA 4JQGA 4WF6A 2OVXA 5I12A 1L6JA 1ZP5A 4G9LA 1QICA 1BKCI 1PWPA 1ZXCA 2EROA 3DTIA 1R55A 1SATA 4EFSA 4AYKA 4H49A 3P1VA 3LIRA 1BKCA 1G05A 1KBCA 5I43A 3F1AA 4H3XA 2L0RA 1BSWA 4DV8A 3TSKA 1JKYA 1BQQM 3DPFA 3HYGA 2MZIA 3BA0A 4HMAA 3WV1A 3ELMA 2PJTA 4GF1A 1G12A 1XFXA 1GE5A 2XS4A 4IN9A 3KMCA 1KAPP 1HFCA 5H8XA 1RMZA 3HY7A 4H76A 1PWWA 1WNIA 2E3XA 1CQRA 1ND1A 5CZMA 1JH1A 4GWNA 2OY2A 1YCMA 3OHLA 3LJTA 4L7AA 4FXQA 4L63A 5I2ZA 4Q1LA 4CTHA 1OS9A 4AUOA 3KEJA 1CGFA 1C8TA 1QIBA 2V4BA 4AXQA 2DW2A 3NX7A 1UTZA 3EHXA 1R1HA 4A3WA 2JSDA 1PWUA 2RJPA 3P24A 2CKIA 2XS3A 2WO8A 1D7XA 4ZR5A 3UVCA 4DPEA 1MMQA 4H30A 1MMRA 3RTTA 2K9CA 2OXWA 3LKAA 1XFWA 1R1IA 4PKQA 5BOTA 1CK7A 1GE7A 1HOVA 1OM8A 3CKIA 3LE9A 1AYKA 3HBVP 3WV3A 3F17A 3TS4A 1TVIA 1UEAA 2X3BA 1S4BP 2MZEA 4AIGA 5BOYA 2HU6A 1CGEA 1BQOA 2POJA 2I47A 2X3CA 1UMTA 3HY9A 1G4KA 5D7WA 2JT5A 3VI1A 1D8MA 966CA 3LEAA 2W0DA 3KRYA 3B2ZA 3ZVSA 4JP4A 5D1TA 1JANA 1OM6A 5I0LA 1QUAA 2OI0A 1OS2A 1KUHA 2JIHA 2SRTA 2W12A 3AYUA 1MMPA 3DTEA 1C3IA 4GQLA 1B8YA 1C7KA 1KUKA 3F15A 1K7QA 1G9KA 3LQBA 2OXUA 3I7GA 2JT6A 1KUIA 3MA2A 3KMEA 1KUGA 1MNCA 2ERPA 1IADA 2WO9A 4XM7A 4A7BA 2KRJA 4JPAA 1JIZA 4HX3A 2MLSA 1B3DA 3EDZA 3WV2A 3K7LA 5CXAA 2AYKA 2W14A 5D2BA 1QIAA 3OHOA 2D1NA 5B5OA 3Q2GA 1JJ9A 5D1SA 1XFVA 1EAKA 4J4MA 3F18A 2YUFA 1ZS0A 2QPJA 2W15A 5I4OA 4DF9A 1GO8P 2N8RA 5D3CA 1Y0VA 2DDYA 2USNA 1A85A 1BZSA 1IABA 830CA 5B5PA 4WKIA 4WK7A 1IAEA 4PKUA 2ERQA 4I35A 2WOAA 4FXYP 2OZRA 5JMYA 1UTTA 3LILA 4ILWD 5BPAA 3DL1A 1YP1A 4IUWA 3HDBA 1CXVA 1SU3A 4PKWA 1CAQA 4H1QA 4WKEA 2MZHA 2OW0A 1JK3A 3LJZA 4XM8A 3LJGA 2X3AA 2FV5A 456CA 2W13A 4G0DA 3TT4A 1USNA 1GE6A 4GWMA 4IJOA 1ASTA 1QJIA 1JAPA 1ROSA 1GXDA 1FBLA 2O36A 1H71P 3LK8A 4R3VA 1XUCA 2K2GA 2D1OA 3DPEA 1J7NA 4H84A 1D8FA 2TCLA 3LQ0A 3KEKA 1BIWA 4FU4A 2Y6DA 1HV5A 1XFZA 1SRPA 5I3MA 1K7IA 3LMCA 2OVZA 3K7NA 1D5JA 3DSLA 5L79A 2O3EA 1GKCA 3EHYA 5D1UA 1XURA 1PWQA 3LIKA 1JAQA 1YOUA 4L19A 1ATLA 1JAOA 1OMJA 3LUNA 3F16A 3HB2P 2OXZA 1FM1A 3B8ZA 2OW2A 1BUVM 2OY4A 1ZVXA 3KECA 1DMTA 4FVLA 2A8HA 3EDIA 3USNA 1GKDA 3LGPA 1IAAA 1OM7A 4ON1A 3GBOA 1EB6A 4PKRA 1CIZA 1IACA 4PKTA 3I7IA 1A86A 1AF0A 2J83A 2YB9A 1K7GA 2J0TA 1XUDA 4WZVA 1BKCE 4GUYA 3HBUP 3RTSA 1BUDA 1HY7A 4PKSA 4DD8A 3EWJA 3G5CA 4PKVA 2JNPA 3L0TA 3TVCA 2Z2DA 1AKLA 1GO7P 2FV9A 2X7MA 2Y6CA 1KUFA 1XAXA 3U1RA 4I03A 4H2EA 3KWVC 3N2VA 1I1IP 3ZXHA 2OW1A 1SLNA 1BM6A 1HTDA 2DW0A 1O0QA 3E8RA 5CUHA 1XM5A 2DW1A 2RJQA 1SMPA 4XM6A 1UMSA 2MLRA 3DWBA 1G49A 3DTKA 1O0TA 3O64A 2DDFA 1RM8A 4GR8A 2AIGP 4H82A 4GR3A 2YIGA 1SLMA 3N2UA 3B92A 1OZ9A 3O2XA 1ZTQA 1IAGA 1JIWP 1Q3AA 1YQYA 4XBHA 2OW9A 3DNGA 3EDGA 1I76A 1R1JA 1CGLA 1OO9A 3AYKA 3Q2HA 3F19A 1DTHA 1ZXVA 4JIJA 3EDHA 5LABA 4GR0A 3HDAP 1XFUA 1I73A 3L0VA 3VTGA 5L7FA 1FLSA 3ZUKA
chains in the Genus database with same CATH topology
3SHIA 3V96B 1Z3JA 1EUBA 1Y93A 2E2DA 3G42A 4QKZA 1PWVA 2CLTA 1QJJA 1MMBA 1XFYA 1HFSA 4L6TA 1R54A 3LUMA 1Y8JA 4XCTA 4JA1A 3AIGA 3KHIA 4JQGA 4WF6A 2OVXA 5I12A 1L6JA 1ZP5A 4G9LA 1QICA 1BKCI 1PWPA 1ZXCA 2EROA 3DTIA 1R55A 1SATA 4EFSA 4AYKA 4H49A 3P1VA 3LIRA 1BKCA 1G05A 1KBCA 5I43A 3F1AA 4H3XA 2L0RA 1BSWA 4DV8A 3TSKA 1JKYA 1BQQM 3DPFA 3HYGA 2MZIA 3BA0A 4HMAA 3WV1A 3ELMA 2PJTA 4GF1A 1G12A 1XFXA 1GE5A 2XS4A 4IN9A 3KMCA 1KAPP 1HFCA 5H8XA 1RMZA 3HY7A 4H76A 1PWWA 1WNIA 2E3XA 1CQRA 1ND1A 5CZMA 1JH1A 4GWNA 2OY2A 1YCMA 3OHLA 3LJTA 4L7AA 4FXQA 4L63A 5I2ZA 4Q1LA 4CTHA 1OS9A 4AUOA 3KEJA 1CGFA 1C8TA 1QIBA 2V4BA 4AXQA 2DW2A 3NX7A 1UTZA 3EHXA 1R1HA 4A3WA 2JSDA 1PWUA 2RJPA 3P24A 2CKIA 2XS3A 2WO8A 1D7XA 4ZR5A 3UVCA 4DPEA 1MMQA 4H30A 1MMRA 3RTTA 2K9CA 2OXWA 3LKAA 1XFWA 1R1IA 4PKQA 5BOTA 1CK7A 1GE7A 1HOVA 1OM8A 3CKIA 3LE9A 1AYKA 3HBVP 3WV3A 3F17A 3TS4A 1UEAA 2X3BA 1S4BP 2MZEA 4AIGA 5BOYA 2HU6A 1CGEA 1BQOA 2POJA 2I47A 2X3CA 1UMTA 3HY9A 1G4KA 5D7WA 2JT5A 3VI1A 1D8MA 966CA 3LEAA 2W0DA 3KRYA 3B2ZA 3ZVSA 4JP4A 5D1TA 1JANA 1OM6A 5I0LA 1QUAA 2OI0A 1OS2A 1KUHA 2JIHA 2SRTA 2W12A 3AYUA 1MMPA 3DTEA 1C3IA 4GQLA 1B8YA 1C7KA 1KUKA 3F15A 1K7QA 1G9KA 3LQBA 2OXUA 3I7GA 2JT6A 1KUIA 3MA2A 3KMEA 1KUGA 1MNCA 2ERPA 1IADA 2WO9A 4XM7A 4A7BA 2KRJA 4JPAA 1JIZA 4HX3A 2MLSA 1B3DA 3EDZA 3WV2A 3K7LA 5CXAA 2AYKA 2W14A 5D2BA 1QIAA 3OHOA 2D1NA 5B5OA 3Q2GA 1JJ9A 5D1SA 1XFVA 1EAKA 4J4MA 3F18A 2YUFA 1ZS0A 2QPJA 2W15A 5I4OA 4DF9A 1GO8P 2N8RA 5D3CA 1Y0VA 2DDYA 2USNA 1A85A 1BZSA 1IABA 830CA 5B5PA 4WKIA 4WK7A 1IAEA 4PKUA 2ERQA 4I35A 2WOAA 4FXYP 2OZRA 5JMYA 1UTTA 3LILA 4ILWD 5BPAA 3DL1A 1YP1A 4IUWA 3HDBA 1CXVA 1SU3A 4PKWA 1CAQA 4H1QA 4WKEA 2MZHA 2OW0A 1JK3A 3LJZA 4XM8A 3LJGA 2X3AA 2FV5A 456CA 2W13A 4G0DA 3TT4A 1USNA 1GE6A 4GWMA 4IJOA 1ASTA 1QJIA 1JAPA 1ROSA 1GXDA 1FBLA 2O36A 1H71P 3LK8A 4R3VA 1XUCA 2K2GA 2D1OA 3DPEA 1J7NA 4H84A 1D8FA 2TCLA 3LQ0A 3KEKA 1BIWA 4FU4A 2Y6DA 1HV5A 1XFZA 1SRPA 5I3MA 1K7IA 3LMCA 2OVZA 3K7NA 1D5JA 3DSLA 5L79A 2O3EA 1GKCA 3EHYA 5D1UA 1XURA 1PWQA 3LIKA 1JAQA 1YOUA 4L19A 1ATLA 1JAOA 1OMJA 3LUNA 3F16A 3HB2P 2OXZA 1FM1A 3B8ZA 2OW2A 1BUVM 2OY4A 1ZVXA 3KECA 1DMTA 4FVLA 2A8HA 3EDIA 3USNA 1GKDA 3LGPA 1IAAA 1OM7A 4ON1A 3GBOA 1EB6A 4PKRA 1CIZA 1IACA 4PKTA 3I7IA 1A86A 1AF0A 2J83A 2YB9A 1K7GA 2J0TA 1XUDA 4WZVA 1BKCE 4GUYA 3HBUP 3RTSA 1BUDA 1HY7A 4PKSA 4DD8A 3EWJA 3G5CA 4PKVA 2JNPA 3L0TA 3TVCA 2Z2DA 1AKLA 1GO7P 2FV9A 2X7MA 2Y6CA 1KUFA 3U1RA 4I03A 4H2EA 3KWVC 3N2VA 1I1IP 3ZXHA 2OW1A 1SLNA 1BM6A 1HTDA 2DW0A 1O0QA 3E8RA 5CUHA 2DW1A 2RJQA 1SMPA 4XM6A 1UMSA 2MLRA 3DWBA 1G49A 3DTKA 1O0TA 3O64A 2DDFA 1RM8A 4GR8A 2AIGP 4H82A 4GR3A 2YIGA 1SLMA 3N2UA 3B92A 3O2XA 1ZTQA 1IAGA 1JIWP 1Q3AA 1YQYA 4XBHA 2OW9A 3DNGA 3EDGA 1I76A 1R1JA 1CGLA 1OO9A 3AYKA 3Q2HA 3F19A 1DTHA 1ZXVA 4JIJA 3EDHA 5LABA 4GR0A 3HDAP 1XFUA 1I73A 3L0VA 3VTGA 5L7FA 1FLSA 3ZUKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SHI A;  3V96 B;  1Z3J A;  1EUB A;  1Y93 A;  2E2D A;  3G42 A;  4QKZ A;  1PWV A;  2CLT A;  1QJJ A;  1MMB A;  1XFY A;  1HFS A;  4L6T A;  1R54 A;  3LUM A;  1Y8J A;  4XCT A;  4JA1 A;  3AIG A;  3KHI A;  4JQG A;  4WF6 A;  2OVX A;  5I12 A;  1L6J A;  1ZP5 A;  4G9L A;  1QIC A;  1BKC I;  1PWP A;  1ZXC A;  2ERO A;  1R55 A;  1SAT A;  4EFS A;  4AYK A;  4H49 A;  3P1V A;  3LIR A;  1BKC A;  1G05 A;  1KBC A;  5I43 A;  3F1A A;  4H3X A;  2L0R A;  1BSW A;  4DV8 A;  3TSK A;  1JKY A;  1BQQ M;  3DPF A;  2MZI A;  3HYG A;  3BA0 A;  4HMA A;  3WV1 A;  3ELM A;  2PJT A;  4GF1 A;  1G12 A;  1XFX A;  1GE5 A;  2XS4 A;  4IN9 A;  3KMC A;  1KAP P;  1HFC A;  5H8X A;  1RMZ A;  3HY7 A;  4H76 A;  1PWW A;  1WNI A;  2E3X A;  1CQR A;  1ND1 A;  5CZM A;  1JH1 A;  4GWN A;  2OY2 A;  1YCM A;  3OHL A;  3LJT A;  4FXQ A;  4L63 A;  5I2Z A;  4Q1L A;  4CTH A;  1OS9 A;  4AUO A;  3KEJ A;  1CGF A;  1C8T A;  1QIB A;  2V4B A;  4AXQ A;  2DW2 A;  3NX7 A;  1UTZ A;  3EHX A;  1R1H A;  4A3W A;  2JSD A;  1PWU A;  2RJP A;  3P24 A;  2CKI A;  2XS3 A;  2WO8 A;  1D7X A;  4ZR5 A;  3UVC A;  4DPE A;  1MMQ A;  4H30 A;  1MMR A;  3RTT A;  2K9C A;  2OXW A;  3LKA A;  1XFW A;  1R1I A;  4PKQ A;  5BOT A;  1CK7 A;  1GE7 A;  1HOV A;  1OM8 A;  3CKI A;  3LE9 A;  1AYK A;  3HBV P;  3WV3 A;  3F17 A;  3TS4 A;  1UEA A;  2X3B A;  1S4B P;  2MZE A;  4AIG A;  5BOY A;  2HU6 A;  1CGE A;  1BQO A;  2POJ A;  2I47 A;  2X3C A;  1UMT A;  3HY9 A;  1G4K A;  5D7W A;  2JT5 A;  3VI1 A;  1D8M A;  966C A;  3LEA A;  2W0D A;  3KRY A;  3B2Z A;  3ZVS A;  4JP4 A;  5D1T A;  1JAN A;  1OM6 A;  5I0L A;  1QUA A;  2OI0 A;  1OS2 A;  1KUH A;  2JIH A;  2SRT A;  2W12 A;  3AYU A;  1MMP A;  1C3I A;  4GQL A;  1B8Y A;  1C7K A;  1KUK A;  3F15 A;  1K7Q A;  1G9K A;  3LQB A;  2OXU A;  3I7G A;  2JT6 A;  1KUI A;  3MA2 A;  3KME A;  1KUG A;  1MNC A;  2ERP A;  1IAD A;  2WO9 A;  4XM7 A;  4A7B A;  2KRJ A;  4JPA A;  1JIZ A;  4HX3 A;  2MLS A;  1B3D A;  3EDZ A;  3WV2 A;  3K7L A;  5CXA A;  2AYK A;  2W14 A;  5D2B A;  1QIA A;  3OHO A;  2D1N A;  5B5O A;  3Q2G A;  1JJ9 A;  5D1S A;  1XFV A;  1EAK A;  4J4M A;  3F18 A;  1ZS0 A;  2QPJ A;  2W15 A;  5I4O A;  4DF9 A;  1GO8 P;  2N8R A;  5D3C A;  1Y0V A;  2DDY A;  2USN A;  1A85 A;  1BZS A;  1IAB A;  830C A;  5B5P A;  4WKI A;  4WK7 A;  1IAE A;  4PKU A;  2ERQ A;  4I35 A;  2WOA A;  4FXY P;  2OZR A;  5JMY A;  1UTT A;  3LIL A;  4ILW D;  5BPA A;  3DL1 A;  1YP1 A;  4IUW A;  3HDB A;  1CXV A;  1SU3 A;  4PKW A;  1CAQ A;  4H1Q A;  4WKE A;  2MZH A;  2OW0 A;  1JK3 A;  3LJZ A;  4XM8 A;  3LJG A;  2X3A A;  2FV5 A;  456C A;  2W13 A;  4G0D A;  3TT4 A;  1USN A;  1GE6 A;  4GWM A;  4IJO A;  1AST A;  1QJI A;  1JAP A;  1ROS A;  1GXD A;  1FBL A;  2O36 A;  1H71 P;  3LK8 A;  4R3V A;  1XUC A;  2K2G A;  2D1O A;  3DPE A;  1J7N A;  4H84 A;  1D8F A;  2TCL A;  3LQ0 A;  3KEK A;  1BIW A;  4FU4 A;  2Y6D A;  1HV5 A;  1XFZ A;  1SRP A;  5I3M A;  1K7I A;  3LMC A;  2OVZ A;  3K7N A;  1D5J A;  3DSL A;  5L79 A;  2O3E A;  1GKC A;  3EHY A;  5D1U A;  1XUR A;  1PWQ A;  3LIK A;  1JAQ A;  1YOU A;  4L19 A;  1ATL A;  1JAO A;  1OMJ A;  3LUN A;  3F16 A;  3HB2 P;  2OXZ A;  1FM1 A;  3B8Z A;  2OW2 A;  1BUV M;  2OY4 A;  1ZVX A;  3KEC A;  1DMT A;  4FVL A;  2A8H A;  3EDI A;  3USN A;  1GKD A;  3LGP A;  1IAA A;  1OM7 A;  4ON1 A;  3GBO A;  1EB6 A;  4PKR A;  1CIZ A;  1IAC A;  4PKT A;  3I7I A;  1A86 A;  1AF0 A;  2J83 A;  2YB9 A;  1K7G A;  2J0T A;  1XUD A;  4WZV A;  1BKC E;  4GUY A;  3HBU P;  3RTS A;  1BUD A;  1HY7 A;  4PKS A;  4DD8 A;  3EWJ A;  3G5C A;  4PKV A;  2JNP A;  3L0T A;  3TVC A;  2Z2D A;  1AKL A;  1GO7 P;  2FV9 A;  2X7M A;  2Y6C A;  1KUF A;  3U1R A;  4I03 A;  4H2E A;  3KWV C;  3N2V A;  1I1I P;  3ZXH A;  2OW1 A;  1SLN A;  1BM6 A;  1HTD A;  2DW0 A;  1O0Q A;  3E8R A;  5CUH A;  2DW1 A;  2RJQ A;  1SMP A;  4XM6 A;  1UMS A;  2MLR A;  3DWB A;  1G49 A;  1O0T A;  3O64 A;  2DDF A;  1RM8 A;  4GR8 A;  2AIG P;  4H82 A;  4GR3 A;  2YIG A;  1SLM A;  3N2U A;  3B92 A;  3O2X A;  1ZTQ A;  1IAG A;  1JIW P;  1Q3A A;  1YQY A;  4XBH A;  2OW9 A;  3DNG A;  3EDG A;  1I76 A;  1R1J A;  1CGL A;  1OO9 A;  3AYK A;  3Q2H A;  3F19 A;  1DTH A;  1ZXV A;  4JIJ A;  3EDH A;  5LAB A;  4GR0 A;  3HDA P;  1XFU A;  1I73 A;  3L0V A;  3VTG A;  5L7F A;  1FLS A;  3ZUK A; 
#chains in the Genus database with same CATH topology
 3SHI A;  3V96 B;  1Z3J A;  1EUB A;  1Y93 A;  2E2D A;  3G42 A;  4QKZ A;  1PWV A;  2CLT A;  1QJJ A;  1MMB A;  1XFY A;  1HFS A;  4L6T A;  1R54 A;  3LUM A;  1Y8J A;  4XCT A;  4JA1 A;  3AIG A;  3KHI A;  4JQG A;  4WF6 A;  2OVX A;  5I12 A;  1L6J A;  1ZP5 A;  4G9L A;  1QIC A;  1BKC I;  1PWP A;  1ZXC A;  2ERO A;  3DTI A;  1R55 A;  1SAT A;  4EFS A;  4AYK A;  4H49 A;  3P1V A;  3LIR A;  1BKC A;  1G05 A;  1KBC A;  5I43 A;  3F1A A;  4H3X A;  2L0R A;  1BSW A;  4DV8 A;  3TSK A;  1JKY A;  1BQQ M;  3DPF A;  3HYG A;  2MZI A;  3BA0 A;  4HMA A;  3WV1 A;  3ELM A;  2PJT A;  4GF1 A;  1G12 A;  1XFX A;  1GE5 A;  2XS4 A;  4IN9 A;  3KMC A;  1KAP P;  1HFC A;  5H8X A;  1RMZ A;  3HY7 A;  4H76 A;  1PWW A;  1WNI A;  2E3X A;  1CQR A;  1ND1 A;  5CZM A;  1JH1 A;  4GWN A;  2OY2 A;  1YCM A;  3OHL A;  3LJT A;  4L7A A;  4FXQ A;  4L63 A;  5I2Z A;  4Q1L A;  4CTH A;  1OS9 A;  4AUO A;  3KEJ A;  1CGF A;  1C8T A;  1QIB A;  2V4B A;  4AXQ A;  2DW2 A;  3NX7 A;  1UTZ A;  3EHX A;  1R1H A;  4A3W A;  2JSD A;  1PWU A;  2RJP A;  3P24 A;  2CKI A;  2XS3 A;  2WO8 A;  1D7X A;  4ZR5 A;  3UVC A;  4DPE A;  1MMQ A;  4H30 A;  1MMR A;  3RTT A;  2K9C A;  2OXW A;  3LKA A;  1XFW A;  1R1I A;  4PKQ A;  5BOT A;  1CK7 A;  1GE7 A;  1HOV A;  1OM8 A;  3CKI A;  3LE9 A;  1AYK A;  3HBV P;  3WV3 A;  3F17 A;  3TS4 A;  1TVI A;  1UEA A;  2X3B A;  1S4B P;  2MZE A;  4AIG A;  5BOY A;  2HU6 A;  1CGE A;  1BQO A;  2POJ A;  2I47 A;  2X3C A;  1UMT A;  3HY9 A;  1G4K A;  5D7W A;  2JT5 A;  3VI1 A;  1D8M A;  966C A;  3LEA A;  2W0D A;  3KRY A;  3B2Z A;  3ZVS A;  4JP4 A;  5D1T A;  1JAN A;  1OM6 A;  5I0L A;  1QUA A;  2OI0 A;  1OS2 A;  1KUH A;  2JIH A;  2SRT A;  2W12 A;  3AYU A;  1MMP A;  3DTE A;  1C3I A;  4GQL A;  1B8Y A;  1C7K A;  1KUK A;  3F15 A;  1K7Q A;  1G9K A;  3LQB A;  2OXU A;  3I7G A;  2JT6 A;  1KUI A;  3MA2 A;  3KME A;  1KUG A;  1MNC A;  2ERP A;  1IAD A;  2WO9 A;  4XM7 A;  4A7B A;  2KRJ A;  4JPA A;  1JIZ A;  4HX3 A;  2MLS A;  1B3D A;  3EDZ A;  3WV2 A;  3K7L A;  5CXA A;  2AYK A;  2W14 A;  5D2B A;  1QIA A;  3OHO A;  2D1N A;  5B5O A;  3Q2G A;  1JJ9 A;  5D1S A;  1XFV A;  1EAK A;  4J4M A;  3F18 A;  2YUF A;  1ZS0 A;  2QPJ A;  2W15 A;  5I4O A;  4DF9 A;  1GO8 P;  2N8R A;  5D3C A;  1Y0V A;  2DDY A;  2USN A;  1A85 A;  1BZS A;  1IAB A;  830C A;  5B5P A;  4WKI A;  4WK7 A;  1IAE A;  4PKU A;  2ERQ A;  4I35 A;  2WOA A;  4FXY P;  2OZR A;  5JMY A;  1UTT A;  3LIL A;  4ILW D;  5BPA A;  3DL1 A;  1YP1 A;  4IUW A;  3HDB A;  1CXV A;  1SU3 A;  4PKW A;  1CAQ A;  4H1Q A;  4WKE A;  2MZH A;  2OW0 A;  1JK3 A;  3LJZ A;  4XM8 A;  3LJG A;  2X3A A;  2FV5 A;  456C A;  2W13 A;  4G0D A;  3TT4 A;  1USN A;  1GE6 A;  4GWM A;  4IJO A;  1AST A;  1QJI A;  1JAP A;  1ROS A;  1GXD A;  1FBL A;  2O36 A;  1H71 P;  3LK8 A;  4R3V A;  1XUC A;  2K2G A;  2D1O A;  3DPE A;  1J7N A;  4H84 A;  1D8F A;  2TCL A;  3LQ0 A;  3KEK A;  1BIW A;  4FU4 A;  2Y6D A;  1HV5 A;  1XFZ A;  1SRP A;  5I3M A;  1K7I A;  3LMC A;  2OVZ A;  3K7N A;  1D5J A;  3DSL A;  5L79 A;  2O3E A;  1GKC A;  3EHY A;  5D1U A;  1XUR A;  1PWQ A;  3LIK A;  1JAQ A;  1YOU A;  4L19 A;  1ATL A;  1JAO A;  1OMJ A;  3LUN A;  3F16 A;  3HB2 P;  2OXZ A;  1FM1 A;  3B8Z A;  2OW2 A;  1BUV M;  2OY4 A;  1ZVX A;  3KEC A;  1DMT A;  4FVL A;  2A8H A;  3EDI A;  3USN A;  1GKD A;  3LGP A;  1IAA A;  1OM7 A;  4ON1 A;  3GBO A;  1EB6 A;  4PKR A;  1CIZ A;  1IAC A;  4PKT A;  3I7I A;  1A86 A;  1AF0 A;  2J83 A;  2YB9 A;  1K7G A;  2J0T A;  1XUD A;  4WZV A;  1BKC E;  4GUY A;  3HBU P;  3RTS A;  1BUD A;  1HY7 A;  4PKS A;  4DD8 A;  3EWJ A;  3G5C A;  4PKV A;  2JNP A;  3L0T A;  3TVC A;  2Z2D A;  1AKL A;  1GO7 P;  2FV9 A;  2X7M A;  2Y6C A;  1KUF A;  1XAX A;  3U1R A;  4I03 A;  4H2E A;  3KWV C;  3N2V A;  1I1I P;  3ZXH A;  2OW1 A;  1SLN A;  1BM6 A;  1HTD A;  2DW0 A;  1O0Q A;  3E8R A;  5CUH A;  1XM5 A;  2DW1 A;  2RJQ A;  1SMP A;  4XM6 A;  1UMS A;  2MLR A;  3DWB A;  1G49 A;  3DTK A;  1O0T A;  3O64 A;  2DDF A;  1RM8 A;  4GR8 A;  2AIG P;  4H82 A;  4GR3 A;  2YIG A;  1SLM A;  3N2U A;  3B92 A;  1OZ9 A;  3O2X A;  1ZTQ A;  1IAG A;  1JIW P;  1Q3A A;  1YQY A;  4XBH A;  2OW9 A;  3DNG A;  3EDG A;  1I76 A;  1R1J A;  1CGL A;  1OO9 A;  3AYK A;  3Q2H A;  3F19 A;  1DTH A;  1ZXV A;  4JIJ A;  3EDH A;  5LAB A;  4GR0 A;  3HDA P;  1XFU A;  1I73 A;  3L0V A;  3VTG A;  5L7F A;  1FLS A;  3ZUK A; 
#chains in the Genus database with same CATH homology
 3SHI A;  3V96 B;  1Z3J A;  1EUB A;  1Y93 A;  2E2D A;  3G42 A;  4QKZ A;  1PWV A;  2CLT A;  1QJJ A;  1MMB A;  1XFY A;  1HFS A;  4L6T A;  1R54 A;  3LUM A;  1Y8J A;  4XCT A;  4JA1 A;  3AIG A;  3KHI A;  4JQG A;  4WF6 A;  2OVX A;  5I12 A;  1L6J A;  1ZP5 A;  4G9L A;  1QIC A;  1BKC I;  1PWP A;  1ZXC A;  2ERO A;  3DTI A;  1R55 A;  1SAT A;  4EFS A;  4AYK A;  4H49 A;  3P1V A;  3LIR A;  1BKC A;  1G05 A;  1KBC A;  5I43 A;  3F1A A;  4H3X A;  2L0R A;  1BSW A;  4DV8 A;  3TSK A;  1JKY A;  1BQQ M;  3DPF A;  3HYG A;  2MZI A;  3BA0 A;  4HMA A;  3WV1 A;  3ELM A;  2PJT A;  4GF1 A;  1G12 A;  1XFX A;  1GE5 A;  2XS4 A;  4IN9 A;  3KMC A;  1KAP P;  1HFC A;  5H8X A;  1RMZ A;  3HY7 A;  4H76 A;  1PWW A;  1WNI A;  2E3X A;  1CQR A;  1ND1 A;  5CZM A;  1JH1 A;  4GWN A;  2OY2 A;  1YCM A;  3OHL A;  3LJT A;  4L7A A;  4FXQ A;  4L63 A;  5I2Z A;  4Q1L A;  4CTH A;  1OS9 A;  4AUO A;  3KEJ A;  1CGF A;  1C8T A;  1QIB A;  2V4B A;  4AXQ A;  2DW2 A;  3NX7 A;  1UTZ A;  3EHX A;  1R1H A;  4A3W A;  2JSD A;  1PWU A;  2RJP A;  3P24 A;  2CKI A;  2XS3 A;  2WO8 A;  1D7X A;  4ZR5 A;  3UVC A;  4DPE A;  1MMQ A;  4H30 A;  1MMR A;  3RTT A;  2K9C A;  2OXW A;  3LKA A;  1XFW A;  1R1I A;  4PKQ A;  5BOT A;  1CK7 A;  1GE7 A;  1HOV A;  1OM8 A;  3CKI A;  3LE9 A;  1AYK A;  3HBV P;  3WV3 A;  3F17 A;  3TS4 A;  1UEA A;  2X3B A;  1S4B P;  2MZE A;  4AIG A;  5BOY A;  2HU6 A;  1CGE A;  1BQO A;  2POJ A;  2I47 A;  2X3C A;  1UMT A;  3HY9 A;  1G4K A;  5D7W A;  2JT5 A;  3VI1 A;  1D8M A;  966C A;  3LEA A;  2W0D A;  3KRY A;  3B2Z A;  3ZVS A;  4JP4 A;  5D1T A;  1JAN A;  1OM6 A;  5I0L A;  1QUA A;  2OI0 A;  1OS2 A;  1KUH A;  2JIH A;  2SRT A;  2W12 A;  3AYU A;  1MMP A;  3DTE A;  1C3I A;  4GQL A;  1B8Y A;  1C7K A;  1KUK A;  3F15 A;  1K7Q A;  1G9K A;  3LQB A;  2OXU A;  3I7G A;  2JT6 A;  1KUI A;  3MA2 A;  3KME A;  1KUG A;  1MNC A;  2ERP A;  1IAD A;  2WO9 A;  4XM7 A;  4A7B A;  2KRJ A;  4JPA A;  1JIZ A;  4HX3 A;  2MLS A;  1B3D A;  3EDZ A;  3WV2 A;  3K7L A;  5CXA A;  2AYK A;  2W14 A;  5D2B A;  1QIA A;  3OHO A;  2D1N A;  5B5O A;  3Q2G A;  1JJ9 A;  5D1S A;  1XFV A;  1EAK A;  4J4M A;  3F18 A;  2YUF A;  1ZS0 A;  2QPJ A;  2W15 A;  5I4O A;  4DF9 A;  1GO8 P;  2N8R A;  5D3C A;  1Y0V A;  2DDY A;  2USN A;  1A85 A;  1BZS A;  1IAB A;  830C A;  5B5P A;  4WKI A;  4WK7 A;  1IAE A;  4PKU A;  2ERQ A;  4I35 A;  2WOA A;  4FXY P;  2OZR A;  5JMY A;  1UTT A;  3LIL A;  4ILW D;  5BPA A;  3DL1 A;  1YP1 A;  4IUW A;  3HDB A;  1CXV A;  1SU3 A;  4PKW A;  1CAQ A;  4H1Q A;  4WKE A;  2MZH A;  2OW0 A;  1JK3 A;  3LJZ A;  4XM8 A;  3LJG A;  2X3A A;  2FV5 A;  456C A;  2W13 A;  4G0D A;  3TT4 A;  1USN A;  1GE6 A;  4GWM A;  4IJO A;  1AST A;  1QJI A;  1JAP A;  1ROS A;  1GXD A;  1FBL A;  2O36 A;  1H71 P;  3LK8 A;  4R3V A;  1XUC A;  2K2G A;  2D1O A;  3DPE A;  1J7N A;  4H84 A;  1D8F A;  2TCL A;  3LQ0 A;  3KEK A;  1BIW A;  4FU4 A;  2Y6D A;  1HV5 A;  1XFZ A;  1SRP A;  5I3M A;  1K7I A;  3LMC A;  2OVZ A;  3K7N A;  1D5J A;  3DSL A;  5L79 A;  2O3E A;  1GKC A;  3EHY A;  5D1U A;  1XUR A;  1PWQ A;  3LIK A;  1JAQ A;  1YOU A;  4L19 A;  1ATL A;  1JAO A;  1OMJ A;  3LUN A;  3F16 A;  3HB2 P;  2OXZ A;  1FM1 A;  3B8Z A;  2OW2 A;  1BUV M;  2OY4 A;  1ZVX A;  3KEC A;  1DMT A;  4FVL A;  2A8H A;  3EDI A;  3USN A;  1GKD A;  3LGP A;  1IAA A;  1OM7 A;  4ON1 A;  3GBO A;  1EB6 A;  4PKR A;  1CIZ A;  1IAC A;  4PKT A;  3I7I A;  1A86 A;  1AF0 A;  2J83 A;  2YB9 A;  1K7G A;  2J0T A;  1XUD A;  4WZV A;  1BKC E;  4GUY A;  3HBU P;  3RTS A;  1BUD A;  1HY7 A;  4PKS A;  4DD8 A;  3EWJ A;  3G5C A;  4PKV A;  2JNP A;  3L0T A;  3TVC A;  2Z2D A;  1AKL A;  1GO7 P;  2FV9 A;  2X7M A;  2Y6C A;  1KUF A;  3U1R A;  4I03 A;  4H2E A;  3KWV C;  3N2V A;  1I1I P;  3ZXH A;  2OW1 A;  1SLN A;  1BM6 A;  1HTD A;  2DW0 A;  1O0Q A;  3E8R A;  5CUH A;  2DW1 A;  2RJQ A;  1SMP A;  4XM6 A;  1UMS A;  2MLR A;  3DWB A;  1G49 A;  3DTK A;  1O0T A;  3O64 A;  2DDF A;  1RM8 A;  4GR8 A;  2AIG P;  4H82 A;  4GR3 A;  2YIG A;  1SLM A;  3N2U A;  3B92 A;  3O2X A;  1ZTQ A;  1IAG A;  1JIW P;  1Q3A A;  1YQY A;  4XBH A;  2OW9 A;  3DNG A;  3EDG A;  1I76 A;  1R1J A;  1CGL A;  1OO9 A;  3AYK A;  3Q2H A;  3F19 A;  1DTH A;  1ZXV A;  4JIJ A;  3EDH A;  5LAB A;  4GR0 A;  3HDA P;  1XFU A;  1I73 A;  3L0V A;  3VTG A;  5L7F A;  1FLS A;  3ZUK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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