5I3MA

Crystal structure of the catalytic domain of mmp-12 in complex with a selective sugar-conjugated thiourea-linked carboxylate zinc-chelator water-soluble inhibitor (dc31).
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
157
structure length
157
Chain Sequence
PVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHQIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 48
structure length 157
sequence length 157
chains with identical sequence B, C, D
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2016-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 5i3mA00
2MZEA 3KMEA 2DW0A 1SMPA 3AYUA 4XM7A 1BQOA 1D5JA 3LILA 1ATLA 1Y8JA 4FXYP 2D1NA 1XFVA 1JJ9A 1C7KA 3KWVC 1GO7P 1UEAA 1KUKA 2X3AA 1SRPA 3Q2HA 4WZVA 1EUBA 3BA0A 3LEAA 3Q2GA 4GWMA 4GWNA 5I4OA 3KEJA 2JNPA 3K7LA 2DW2A 3KRYA 3P1VA 2QPJA 4PKQA 3E8RA 4AYKA 1D8FA 1BQQM 3L0TA 1Y0VA 4DPEA 1CXVA 2OW9A 2AIGP 1MMBA 4L19A 5CUHA 4PKVA 456CA 3DL1A 1D8MA 4WKEA 1JAPA 3WV3A 3OHLA 4GR0A 1JK3A 4ON1A 4XM8A 2W15A 1GE6A 2RJPA 2V4BA 4H1QA 2JSDA 1JANA 2D1OA 3KHIA 1QJJA 1DTHA 2J83A 1SU3A 3P24A 3WV1A 3N2UA 3HYGA 1IACA 1YCMA 1RM8A 4J4MA 1O0QA 4GR8A 4PKRA 4L63A 1WNIA 2A8HA 1Z3JA 4PKTA 4GQLA 3LMCA 5CXAA 3L0VA 1CGLA 2YB9A 3RTSA 2K9CA 1CGEA 4XBHA 3EHYA 1AYKA 1G05A 4ILWD 1BZSA 4GUYA 4A7BA 3LUNA 2OW2A 2JIHA 3WV2A 2JT6A 1IAEA 2MLRA 1ZXCA 1PWVA 3EWJA 3UVCA 1JKYA 1XUCA 2X3CA 1B8YA 1BUDA 1AF0A 1OS2A 2J0TA 5I12A 1QJIA 1ND1A 4R3VA 5I0LA 2SRTA 2YIGA 3B92A 3F18A 4I35A 2OVXA 4WK7A 1JIWP 1KBCA 1Q3AA 3DNGA 2JT5A 1QUAA 1YQYA 3ZXHA 2RJQA 1EAKA 2W14A 2O3EA 4H82A 2CKIA 1GXDA 2EROA 4FU4A 5I43A 2WO9A 3I7IA 1G4KA 1CK7A 4FXQA 3HBVP 3F15A 1AKLA 4DF9A 4AXQA 1OM8A 2MZHA 3DPEA 1BKCE 5LABA 1HOVA 5I2ZA 4PKUA 1R1JA 1QIBA 4CTHA 3B2ZA 5CZMA 3LJZA 2HU6A 2I47A 5BOYA 1JIZA 4G0DA 2XS4A 1HV5A 3LKAA 1L6JA 3TSKA 1SLMA 3MA2A 1CIZA 1H71P 3EDHA 1PWWA 5D3CA 4IN9A 1G49A 3SHIA 4HX3A 3LIKA 1B3DA 1FBLA 1OM6A 2OVZA 1CAQA 4WF6A 2OY4A 5B5OA 1EB6A 2OXUA 2OI0A 3LJTA 4IUWA 4FVLA 1RMZA 1GKCA 1GE5A 2DDFA 3DPFA 4AIGA 1XFWA 2ERPA 4L6TA 2USNA 3KMCA 3G42A 2Y6CA 2Z2DA 1G12A 1R55A 5BOTA 4AUOA 2MLSA 1JAQA 3O2XA 2O36A 1SLNA 1K7GA 1UTTA 1C8TA 1KUFA 2WOAA 3EDIA 1BM6A 4WKIA 2W12A 4G9LA 2OW1A 2FV5A 1I76A 1I73A 3EDGA 2POJA 3HY7A 2AYKA 1BKCA 3TVCA 1XUDA 1XURA 2KRJA 1UMTA 2DDYA 1OMJA 2E3XA 3ZVSA 2X3BA 2FV9A 3HY9A 1OM7A 2W13A 1ASTA 5D2BA 2MZIA 1YP1A 3LE9A 4GF1A 5JMYA 4EFSA 1ROSA 966CA 5H8XA 3LGPA 1R54A 1PWQA 4H2EA 1BSWA 2TCLA 4H49A 1C3IA 3F1AA 2W0DA 1HTDA 1QICA 2N8RA 2DW1A 1A86A 3ZUKA 1R1IA 3VI1A 1MMQA 1CQRA 1UMSA 1ZS0A 1ZTQA 3F17A 1OO9A 4H30A 3USNA 1BKCI 3O64A 2CLTA 3F19A 2OXZA 1S4BP 1MNCA 5L7FA 3HB2P 2OXWA 1I1IP 4H3XA 3LK8A 1GE7A 3TS4A 1SATA 4QKZA 1HY7A 2XS3A 1GKDA 3EHXA 1MMPA 1J7NA 1KUHA 1KUGA 3DSLA 1G9KA 3G5CA 4H76A 1K7QA 3EDZA 3AYKA 3GBOA 1JH1A 5D1TA 1FM1A 3TT4A 2OZRA 2Y6DA 3B8ZA 3HDAP 3I7GA 3AIGA 2PJTA 1XFZA 4JP4A 1QIAA 1MMRA 4GR3A 1HFSA 4DD8A 3LQ0A 1IAGA 4XM6A 1OS9A 1IABA 5B5PA 4A3WA 3KEKA 3ELMA 1R1HA 1FLSA 4PKWA 1JAOA 3HBUP 1GO8P 2WO8A 2OW0A 4XCTA 4PKSA 1ZP5A 4JIJA 1KAPP 1IAAA 1ZXVA 2ERQA 5L79A 3NX7A 1BIWA 4I03A 4DV8A 5D7WA 1XFUA 3LJGA 3N2VA 4JA1A 4HMAA 1USNA 4Q1LA 4H84A 1HFCA 3K7NA 1XFYA 1ZVXA 3VTGA 1KUIA 2E2DA 3F16A 3DWBA 1UTZA 5D1SA 3KECA 3LIRA 1A85A 5D1UA 1YOUA 1PWPA 3CKIA 1XFXA 5I3MA 1PWUA 3LUMA 1DMTA 1Y93A 4ZR5A 4JQGA 1IADA 3RTTA 1BUVM 2X7MA 4JPAA 1D7XA 830CA 3HDBA 1K7IA 1CGFA 3LQBA 4IJOA 5BPAA 3U1RA 2OY2A 1O0TA 3V96B 2K2GA 2L0RA 3OHOA
chains in the Genus database with same CATH superfamily
2MZEA 3KMEA 2DW0A 1SMPA 3AYUA 4XM7A 1BQOA 1D5JA 3LILA 1ATLA 1Y8JA 4FXYP 2D1NA 1XFVA 1JJ9A 1C7KA 3KWVC 1GO7P 1UEAA 1KUKA 2X3AA 1SRPA 2YUFA 3Q2HA 4WZVA 1EUBA 3BA0A 3LEAA 3Q2GA 4GWMA 4GWNA 5I4OA 3KEJA 2JNPA 3K7LA 2DW2A 3KRYA 3P1VA 2QPJA 4PKQA 3E8RA 1XM5A 4AYKA 1D8FA 1BQQM 3L0TA 1Y0VA 4DPEA 1CXVA 2OW9A 2AIGP 1MMBA 4L19A 5CUHA 1OZ9A 4PKVA 456CA 3DL1A 1D8MA 4WKEA 1JAPA 3WV3A 3OHLA 4GR0A 1JK3A 4ON1A 4XM8A 2W15A 1GE6A 2RJPA 2V4BA 4H1QA 2JSDA 1JANA 2D1OA 3KHIA 1QJJA 1DTHA 2J83A 1SU3A 3P24A 3WV1A 3N2UA 3HYGA 1IACA 1YCMA 1RM8A 4J4MA 1O0QA 4GR8A 4PKRA 4L63A 1WNIA 2A8HA 1Z3JA 4PKTA 4GQLA 3LMCA 5CXAA 3L0VA 1CGLA 2YB9A 3RTSA 2K9CA 1CGEA 4XBHA 3EHYA 1AYKA 1G05A 4ILWD 1BZSA 4GUYA 4A7BA 3LUNA 2OW2A 2JIHA 3WV2A 2JT6A 1IAEA 2MLRA 1ZXCA 3EWJA 1PWVA 3UVCA 1JKYA 1XUCA 2X3CA 1B8YA 1BUDA 1AF0A 1OS2A 2J0TA 5I12A 1QJIA 1ND1A 4R3VA 5I0LA 2SRTA 2YIGA 3B92A 3F18A 4I35A 2OVXA 4WK7A 1JIWP 1KBCA 1Q3AA 3DNGA 2JT5A 1QUAA 1YQYA 3ZXHA 2RJQA 1EAKA 2W14A 2O3EA 4H82A 2CKIA 1GXDA 2EROA 4FU4A 5I43A 2WO9A 3I7IA 1G4KA 1CK7A 4FXQA 3HBVP 3F15A 1AKLA 4DF9A 4AXQA 1OM8A 2MZHA 3DPEA 1BKCE 5LABA 1HOVA 5I2ZA 4PKUA 1R1JA 1QIBA 4CTHA 3B2ZA 5CZMA 3LJZA 2HU6A 2I47A 5BOYA 1JIZA 4G0DA 2XS4A 1HV5A 3LKAA 1L6JA 3TSKA 1SLMA 3MA2A 1CIZA 1H71P 3EDHA 1PWWA 5D3CA 4IN9A 1G49A 3SHIA 4HX3A 3LIKA 1B3DA 1FBLA 1OM6A 2OVZA 1CAQA 4WF6A 2OY4A 5B5OA 1EB6A 2OXUA 2OI0A 3LJTA 4IUWA 4FVLA 1RMZA 1GKCA 1GE5A 2DDFA 3DPFA 4AIGA 1XFWA 2ERPA 4L6TA 2USNA 3KMCA 3G42A 2Y6CA 2Z2DA 1G12A 1R55A 5BOTA 4AUOA 2MLSA 1JAQA 3O2XA 2O36A 1SLNA 1K7GA 1UTTA 1C8TA 1KUFA 2WOAA 3EDIA 1BM6A 4WKIA 2W12A 4G9LA 2OW1A 2FV5A 1I76A 1I73A 3EDGA 2POJA 1TVIA 3HY7A 2AYKA 1BKCA 3TVCA 1XUDA 1XURA 2KRJA 1UMTA 2DDYA 1OMJA 2E3XA 3ZVSA 2X3BA 1XAXA 2FV9A 3HY9A 4L7AA 1OM7A 2W13A 1ASTA 5D2BA 2MZIA 1YP1A 3LE9A 4GF1A 5JMYA 4EFSA 1ROSA 966CA 5H8XA 3LGPA 1R54A 1PWQA 4H2EA 1BSWA 2TCLA 4H49A 1C3IA 3F1AA 2W0DA 3DTEA 1HTDA 1QICA 2N8RA 2DW1A 1A86A 3ZUKA 1R1IA 3VI1A 1MMQA 1CQRA 1UMSA 1ZS0A 1ZTQA 3F17A 1OO9A 4H30A 3USNA 1BKCI 3O64A 2CLTA 3F19A 2OXZA 1S4BP 1MNCA 5L7FA 3HB2P 2OXWA 1I1IP 4H3XA 3LK8A 1GE7A 3TS4A 1SATA 4QKZA 1HY7A 2XS3A 1GKDA 3EHXA 1MMPA 1J7NA 1KUHA 1KUGA 3DSLA 1G9KA 3G5CA 4H76A 1K7QA 3EDZA 3AYKA 3GBOA 1JH1A 5D1TA 1FM1A 3TT4A 2OZRA 2Y6DA 3B8ZA 3HDAP 3I7GA 3AIGA 2PJTA 1XFZA 4JP4A 1QIAA 1MMRA 4GR3A 1HFSA 4DD8A 3LQ0A 1IAGA 4XM6A 1OS9A 1IABA 5B5PA 4A3WA 3KEKA 3ELMA 1R1HA 1FLSA 4PKWA 1JAOA 3HBUP 1GO8P 2WO8A 2OW0A 4XCTA 4PKSA 1ZP5A 4JIJA 1KAPP 1IAAA 1ZXVA 2ERQA 5L79A 3NX7A 1BIWA 4I03A 4DV8A 5D7WA 1XFUA 3LJGA 3N2VA 4JA1A 4HMAA 1USNA 4Q1LA 4H84A 1HFCA 3K7NA 1XFYA 1ZVXA 3VTGA 1KUIA 2E2DA 3F16A 3DWBA 1UTZA 5D1SA 3KECA 3LIRA 1A85A 5D1UA 1YOUA 1PWPA 3CKIA 1XFXA 5I3MA 1PWUA 3LUMA 1DMTA 1Y93A 4ZR5A 4JQGA 1IADA 3RTTA 1BUVM 2X7MA 4JPAA 1D7XA 830CA 3HDBA 1K7IA 1CGFA 3LQBA 4IJOA 3DTIA 5BPAA 3U1RA 2OY2A 1O0TA 3V96B 2K2GA 2L0RA 3OHOA 3DTKA
chains in the Genus database with same CATH topology
2MZEA 3KMEA 2DW0A 1SMPA 3AYUA 4XM7A 1BQOA 1D5JA 3LILA 1ATLA 1Y8JA 4FXYP 2D1NA 1XFVA 1JJ9A 1C7KA 3KWVC 1GO7P 1UEAA 1KUKA 2X3AA 1SRPA 2YUFA 3Q2HA 4WZVA 1EUBA 3BA0A 3LEAA 3Q2GA 4GWMA 4GWNA 5I4OA 3KEJA 2JNPA 3K7LA 2DW2A 3KRYA 3P1VA 2QPJA 4PKQA 3E8RA 4AYKA 1D8FA 1BQQM 3L0TA 1Y0VA 4DPEA 1CXVA 2OW9A 2AIGP 1MMBA 4L19A 5CUHA 4PKVA 456CA 3DL1A 1D8MA 4WKEA 1JAPA 3WV3A 3OHLA 4GR0A 1JK3A 4ON1A 4XM8A 2W15A 1GE6A 2RJPA 2V4BA 4H1QA 2JSDA 1JANA 2D1OA 3KHIA 1QJJA 1DTHA 2J83A 1SU3A 3P24A 3WV1A 3N2UA 3HYGA 1IACA 1YCMA 1RM8A 4J4MA 1O0QA 4GR8A 4PKRA 4L63A 1WNIA 2A8HA 1Z3JA 4PKTA 4GQLA 3LMCA 5CXAA 3L0VA 1CGLA 2YB9A 3RTSA 2K9CA 1CGEA 4XBHA 3EHYA 1AYKA 1G05A 4ILWD 1BZSA 4GUYA 4A7BA 3LUNA 2OW2A 2JIHA 3WV2A 2JT6A 1IAEA 2MLRA 1ZXCA 3EWJA 1PWVA 3UVCA 1JKYA 1XUCA 2X3CA 1B8YA 1BUDA 1AF0A 1OS2A 2J0TA 5I12A 1QJIA 1ND1A 4R3VA 5I0LA 2SRTA 2YIGA 3B92A 3F18A 4I35A 2OVXA 4WK7A 1JIWP 1KBCA 1Q3AA 3DNGA 2JT5A 1QUAA 1YQYA 3ZXHA 2RJQA 1EAKA 2W14A 2O3EA 4H82A 2CKIA 1GXDA 2EROA 4FU4A 5I43A 2WO9A 3I7IA 1G4KA 1CK7A 4FXQA 3HBVP 3F15A 1AKLA 4DF9A 4AXQA 1OM8A 2MZHA 3DPEA 1BKCE 5LABA 1HOVA 5I2ZA 4PKUA 1R1JA 1QIBA 4CTHA 3B2ZA 5CZMA 3LJZA 2HU6A 2I47A 5BOYA 1JIZA 4G0DA 2XS4A 1HV5A 3LKAA 1L6JA 3TSKA 1SLMA 3MA2A 1CIZA 1H71P 3EDHA 1PWWA 5D3CA 4IN9A 1G49A 3SHIA 4HX3A 3LIKA 1B3DA 1FBLA 1OM6A 2OVZA 1CAQA 4WF6A 2OY4A 5B5OA 1EB6A 2OXUA 2OI0A 3LJTA 4IUWA 4FVLA 1RMZA 1GKCA 1GE5A 2DDFA 3DPFA 4AIGA 1XFWA 2ERPA 4L6TA 2USNA 3KMCA 3G42A 2Y6CA 2Z2DA 1G12A 1R55A 5BOTA 4AUOA 2MLSA 1JAQA 3O2XA 2O36A 1SLNA 1K7GA 1UTTA 1C8TA 1KUFA 2WOAA 3EDIA 1BM6A 4WKIA 2W12A 4G9LA 2OW1A 2FV5A 1I76A 1I73A 3EDGA 2POJA 3HY7A 2AYKA 1BKCA 3TVCA 1XUDA 1XURA 2KRJA 1UMTA 2DDYA 1OMJA 2E3XA 3ZVSA 2X3BA 2FV9A 3HY9A 4L7AA 1OM7A 2W13A 1ASTA 5D2BA 2MZIA 1YP1A 3LE9A 4GF1A 5JMYA 4EFSA 1ROSA 966CA 5H8XA 3LGPA 1R54A 1PWQA 4H2EA 1BSWA 2TCLA 4H49A 1C3IA 3F1AA 2W0DA 3DTEA 1HTDA 1QICA 2N8RA 2DW1A 1A86A 3ZUKA 1R1IA 3VI1A 1MMQA 1CQRA 1UMSA 1ZS0A 1ZTQA 3F17A 1OO9A 4H30A 3USNA 1BKCI 3O64A 2CLTA 3F19A 2OXZA 1S4BP 1MNCA 5L7FA 3HB2P 2OXWA 1I1IP 4H3XA 3LK8A 1GE7A 3TS4A 1SATA 4QKZA 1HY7A 2XS3A 1GKDA 3EHXA 1MMPA 1J7NA 1KUHA 1KUGA 3DSLA 1G9KA 3G5CA 4H76A 1K7QA 3EDZA 3AYKA 3GBOA 1JH1A 5D1TA 1FM1A 3TT4A 2OZRA 2Y6DA 3B8ZA 3HDAP 3I7GA 3AIGA 2PJTA 1XFZA 4JP4A 1QIAA 1MMRA 4GR3A 1HFSA 4DD8A 3LQ0A 1IAGA 4XM6A 1OS9A 1IABA 5B5PA 4A3WA 3KEKA 3ELMA 1R1HA 1FLSA 4PKWA 1JAOA 3HBUP 1GO8P 2WO8A 2OW0A 4XCTA 4PKSA 1ZP5A 4JIJA 1KAPP 1IAAA 1ZXVA 2ERQA 5L79A 3NX7A 1BIWA 4I03A 4DV8A 5D7WA 1XFUA 3LJGA 3N2VA 4JA1A 4HMAA 1USNA 4Q1LA 4H84A 1HFCA 3K7NA 1XFYA 1ZVXA 3VTGA 1KUIA 2E2DA 3F16A 3DWBA 1UTZA 5D1SA 3KECA 3LIRA 1A85A 5D1UA 1YOUA 1PWPA 3CKIA 1XFXA 5I3MA 1PWUA 3LUMA 1DMTA 1Y93A 4ZR5A 4JQGA 1IADA 3RTTA 1BUVM 2X7MA 4JPAA 1D7XA 830CA 3HDBA 1K7IA 1CGFA 3LQBA 4IJOA 3DTIA 5BPAA 3U1RA 2OY2A 1O0TA 3V96B 2K2GA 2L0RA 3OHOA 3DTKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MZE A;  3KME A;  2DW0 A;  1SMP A;  3AYU A;  4XM7 A;  1BQO A;  1D5J A;  3LIL A;  1ATL A;  1Y8J A;  4FXY P;  2D1N A;  1XFV A;  1JJ9 A;  1C7K A;  3KWV C;  1GO7 P;  1UEA A;  1KUK A;  2X3A A;  1SRP A;  3Q2H A;  4WZV A;  1EUB A;  3BA0 A;  3LEA A;  3Q2G A;  4GWM A;  4GWN A;  5I4O A;  3KEJ A;  2JNP A;  3K7L A;  2DW2 A;  3KRY A;  3P1V A;  2QPJ A;  4PKQ A;  3E8R A;  4AYK A;  1D8F A;  1BQQ M;  3L0T A;  1Y0V A;  4DPE A;  1CXV A;  2OW9 A;  2AIG P;  1MMB A;  4L19 A;  5CUH A;  4PKV A;  456C A;  3DL1 A;  1D8M A;  4WKE A;  1JAP A;  3WV3 A;  3OHL A;  4GR0 A;  1JK3 A;  4ON1 A;  4XM8 A;  2W15 A;  1GE6 A;  2RJP A;  2V4B A;  4H1Q A;  2JSD A;  1JAN A;  2D1O A;  3KHI A;  1QJJ A;  1DTH A;  2J83 A;  1SU3 A;  3P24 A;  3WV1 A;  3N2U A;  3HYG A;  1IAC A;  1YCM A;  1RM8 A;  4J4M A;  1O0Q A;  4GR8 A;  4PKR A;  4L63 A;  1WNI A;  2A8H A;  1Z3J A;  4PKT A;  4GQL A;  3LMC A;  5CXA A;  3L0V A;  1CGL A;  2YB9 A;  3RTS A;  2K9C A;  1CGE A;  4XBH A;  3EHY A;  1AYK A;  1G05 A;  4ILW D;  1BZS A;  4GUY A;  4A7B A;  3LUN A;  2OW2 A;  2JIH A;  3WV2 A;  2JT6 A;  1IAE A;  2MLR A;  1ZXC A;  1PWV A;  3EWJ A;  3UVC A;  1JKY A;  1XUC A;  2X3C A;  1B8Y A;  1BUD A;  1AF0 A;  1OS2 A;  2J0T A;  5I12 A;  1QJI A;  1ND1 A;  4R3V A;  5I0L A;  2SRT A;  2YIG A;  3B92 A;  3F18 A;  4I35 A;  2OVX A;  4WK7 A;  1JIW P;  1KBC A;  1Q3A A;  3DNG A;  2JT5 A;  1QUA A;  1YQY A;  3ZXH A;  2RJQ A;  1EAK A;  2W14 A;  2O3E A;  4H82 A;  2CKI A;  1GXD A;  2ERO A;  4FU4 A;  5I43 A;  2WO9 A;  3I7I A;  1G4K A;  1CK7 A;  4FXQ A;  3HBV P;  3F15 A;  1AKL A;  4DF9 A;  4AXQ A;  1OM8 A;  2MZH A;  3DPE A;  1BKC E;  5LAB A;  1HOV A;  5I2Z A;  4PKU A;  1R1J A;  1QIB A;  4CTH A;  3B2Z A;  5CZM A;  3LJZ A;  2HU6 A;  2I47 A;  5BOY A;  1JIZ A;  4G0D A;  2XS4 A;  1HV5 A;  3LKA A;  1L6J A;  3TSK A;  1SLM A;  3MA2 A;  1CIZ A;  1H71 P;  3EDH A;  1PWW A;  5D3C A;  4IN9 A;  1G49 A;  3SHI A;  4HX3 A;  3LIK A;  1B3D A;  1FBL A;  1OM6 A;  2OVZ A;  1CAQ A;  4WF6 A;  2OY4 A;  5B5O A;  1EB6 A;  2OXU A;  2OI0 A;  3LJT A;  4IUW A;  4FVL A;  1RMZ A;  1GKC A;  1GE5 A;  2DDF A;  3DPF A;  4AIG A;  1XFW A;  2ERP A;  4L6T A;  2USN A;  3KMC A;  3G42 A;  2Y6C A;  2Z2D A;  1G12 A;  1R55 A;  5BOT A;  4AUO A;  2MLS A;  1JAQ A;  3O2X A;  2O36 A;  1SLN A;  1K7G A;  1UTT A;  1C8T A;  1KUF A;  2WOA A;  3EDI A;  1BM6 A;  4WKI A;  2W12 A;  4G9L A;  2OW1 A;  2FV5 A;  1I76 A;  1I73 A;  3EDG A;  2POJ A;  3HY7 A;  2AYK A;  1BKC A;  3TVC A;  1XUD A;  1XUR A;  2KRJ A;  1UMT A;  2DDY A;  1OMJ A;  2E3X A;  3ZVS A;  2X3B A;  2FV9 A;  3HY9 A;  1OM7 A;  2W13 A;  1AST A;  5D2B A;  2MZI A;  1YP1 A;  3LE9 A;  4GF1 A;  5JMY A;  4EFS A;  1ROS A;  966C A;  5H8X A;  3LGP A;  1R54 A;  1PWQ A;  4H2E A;  1BSW A;  2TCL A;  4H49 A;  1C3I A;  3F1A A;  2W0D A;  1HTD A;  1QIC A;  2N8R A;  2DW1 A;  1A86 A;  3ZUK A;  1R1I A;  3VI1 A;  1MMQ A;  1CQR A;  1UMS A;  1ZS0 A;  1ZTQ A;  3F17 A;  1OO9 A;  4H30 A;  3USN A;  1BKC I;  3O64 A;  2CLT A;  3F19 A;  2OXZ A;  1S4B P;  1MNC A;  5L7F A;  3HB2 P;  2OXW A;  1I1I P;  4H3X A;  3LK8 A;  1GE7 A;  3TS4 A;  1SAT A;  4QKZ A;  1HY7 A;  2XS3 A;  1GKD A;  3EHX A;  1MMP A;  1J7N A;  1KUH A;  1KUG A;  3DSL A;  1G9K A;  3G5C A;  4H76 A;  1K7Q A;  3EDZ A;  3AYK A;  3GBO A;  1JH1 A;  5D1T A;  1FM1 A;  3TT4 A;  2OZR A;  2Y6D A;  3B8Z A;  3HDA P;  3I7G A;  3AIG A;  2PJT A;  1XFZ A;  4JP4 A;  1QIA A;  1MMR A;  4GR3 A;  1HFS A;  4DD8 A;  3LQ0 A;  1IAG A;  4XM6 A;  1OS9 A;  1IAB A;  5B5P A;  4A3W A;  3KEK A;  3ELM A;  1R1H A;  1FLS A;  4PKW A;  1JAO A;  3HBU P;  1GO8 P;  2WO8 A;  2OW0 A;  4XCT A;  4PKS A;  1ZP5 A;  4JIJ A;  1KAP P;  1IAA A;  1ZXV A;  2ERQ A;  5L79 A;  3NX7 A;  1BIW A;  4I03 A;  4DV8 A;  5D7W A;  1XFU A;  3LJG A;  3N2V A;  4JA1 A;  4HMA A;  1USN A;  4Q1L A;  4H84 A;  1HFC A;  3K7N A;  1XFY A;  1ZVX A;  3VTG A;  1KUI A;  2E2D A;  3F16 A;  3DWB A;  1UTZ A;  5D1S A;  3KEC A;  3LIR A;  1A85 A;  5D1U A;  1YOU A;  1PWP A;  3CKI A;  1XFX A;  5I3M A;  1PWU A;  3LUM A;  1DMT A;  1Y93 A;  4ZR5 A;  4JQG A;  1IAD A;  3RTT A;  1BUV M;  2X7M A;  4JPA A;  1D7X A;  830C A;  3HDB A;  1K7I A;  1CGF A;  3LQB A;  4IJO A;  5BPA A;  3U1R A;  2OY2 A;  1O0T A;  3V96 B;  2K2G A;  2L0R A;  3OHO A; 
#chains in the Genus database with same CATH topology
 2MZE A;  3KME A;  2DW0 A;  1SMP A;  3AYU A;  4XM7 A;  1BQO A;  1D5J A;  3LIL A;  1ATL A;  1Y8J A;  4FXY P;  2D1N A;  1XFV A;  1JJ9 A;  1C7K A;  3KWV C;  1GO7 P;  1UEA A;  1KUK A;  2X3A A;  1SRP A;  2YUF A;  3Q2H A;  4WZV A;  1EUB A;  3BA0 A;  3LEA A;  3Q2G A;  4GWM A;  4GWN A;  5I4O A;  3KEJ A;  2JNP A;  3K7L A;  2DW2 A;  3KRY A;  3P1V A;  2QPJ A;  4PKQ A;  3E8R A;  1XM5 A;  4AYK A;  1D8F A;  1BQQ M;  3L0T A;  1Y0V A;  4DPE A;  1CXV A;  2OW9 A;  2AIG P;  1MMB A;  4L19 A;  5CUH A;  1OZ9 A;  4PKV A;  456C A;  3DL1 A;  1D8M A;  4WKE A;  1JAP A;  3WV3 A;  3OHL A;  4GR0 A;  1JK3 A;  4ON1 A;  4XM8 A;  2W15 A;  1GE6 A;  2RJP A;  2V4B A;  4H1Q A;  2JSD A;  1JAN A;  2D1O A;  3KHI A;  1QJJ A;  1DTH A;  2J83 A;  1SU3 A;  3P24 A;  3WV1 A;  3N2U A;  3HYG A;  1IAC A;  1YCM A;  1RM8 A;  4J4M A;  1O0Q A;  4GR8 A;  4PKR A;  4L63 A;  1WNI A;  2A8H A;  1Z3J A;  4PKT A;  4GQL A;  3LMC A;  5CXA A;  3L0V A;  1CGL A;  2YB9 A;  3RTS A;  2K9C A;  1CGE A;  4XBH A;  3EHY A;  1AYK A;  1G05 A;  4ILW D;  1BZS A;  4GUY A;  4A7B A;  3LUN A;  2OW2 A;  2JIH A;  3WV2 A;  2JT6 A;  1IAE A;  2MLR A;  1ZXC A;  3EWJ A;  1PWV A;  3UVC A;  1JKY A;  1XUC A;  2X3C A;  1B8Y A;  1BUD A;  1AF0 A;  1OS2 A;  2J0T A;  5I12 A;  1QJI A;  1ND1 A;  4R3V A;  5I0L A;  2SRT A;  2YIG A;  3B92 A;  3F18 A;  4I35 A;  2OVX A;  4WK7 A;  1JIW P;  1KBC A;  1Q3A A;  3DNG A;  2JT5 A;  1QUA A;  1YQY A;  3ZXH A;  2RJQ A;  1EAK A;  2W14 A;  2O3E A;  4H82 A;  2CKI A;  1GXD A;  2ERO A;  4FU4 A;  5I43 A;  2WO9 A;  3I7I A;  1G4K A;  1CK7 A;  4FXQ A;  3HBV P;  3F15 A;  1AKL A;  4DF9 A;  4AXQ A;  1OM8 A;  2MZH A;  3DPE A;  1BKC E;  5LAB A;  1HOV A;  5I2Z A;  4PKU A;  1R1J A;  1QIB A;  4CTH A;  3B2Z A;  5CZM A;  3LJZ A;  2HU6 A;  2I47 A;  5BOY A;  1JIZ A;  4G0D A;  2XS4 A;  1HV5 A;  3LKA A;  1L6J A;  3TSK A;  1SLM A;  3MA2 A;  1CIZ A;  1H71 P;  3EDH A;  1PWW A;  5D3C A;  4IN9 A;  1G49 A;  3SHI A;  4HX3 A;  3LIK A;  1B3D A;  1FBL A;  1OM6 A;  2OVZ A;  1CAQ A;  4WF6 A;  2OY4 A;  5B5O A;  1EB6 A;  2OXU A;  2OI0 A;  3LJT A;  4IUW A;  4FVL A;  1RMZ A;  1GKC A;  1GE5 A;  2DDF A;  3DPF A;  4AIG A;  1XFW A;  2ERP A;  4L6T A;  2USN A;  3KMC A;  3G42 A;  2Y6C A;  2Z2D A;  1G12 A;  1R55 A;  5BOT A;  4AUO A;  2MLS A;  1JAQ A;  3O2X A;  2O36 A;  1SLN A;  1K7G A;  1UTT A;  1C8T A;  1KUF A;  2WOA A;  3EDI A;  1BM6 A;  4WKI A;  2W12 A;  4G9L A;  2OW1 A;  2FV5 A;  1I76 A;  1I73 A;  3EDG A;  2POJ A;  1TVI A;  3HY7 A;  2AYK A;  1BKC A;  3TVC A;  1XUD A;  1XUR A;  2KRJ A;  1UMT A;  2DDY A;  1OMJ A;  2E3X A;  3ZVS A;  2X3B A;  1XAX A;  2FV9 A;  3HY9 A;  4L7A A;  1OM7 A;  2W13 A;  1AST A;  5D2B A;  2MZI A;  1YP1 A;  3LE9 A;  4GF1 A;  5JMY A;  4EFS A;  1ROS A;  966C A;  5H8X A;  3LGP A;  1R54 A;  1PWQ A;  4H2E A;  1BSW A;  2TCL A;  4H49 A;  1C3I A;  3F1A A;  2W0D A;  3DTE A;  1HTD A;  1QIC A;  2N8R A;  2DW1 A;  1A86 A;  3ZUK A;  1R1I A;  3VI1 A;  1MMQ A;  1CQR A;  1UMS A;  1ZS0 A;  1ZTQ A;  3F17 A;  1OO9 A;  4H30 A;  3USN A;  1BKC I;  3O64 A;  2CLT A;  3F19 A;  2OXZ A;  1S4B P;  1MNC A;  5L7F A;  3HB2 P;  2OXW A;  1I1I P;  4H3X A;  3LK8 A;  1GE7 A;  3TS4 A;  1SAT A;  4QKZ A;  1HY7 A;  2XS3 A;  1GKD A;  3EHX A;  1MMP A;  1J7N A;  1KUH A;  1KUG A;  3DSL A;  1G9K A;  3G5C A;  4H76 A;  1K7Q A;  3EDZ A;  3AYK A;  3GBO A;  1JH1 A;  5D1T A;  1FM1 A;  3TT4 A;  2OZR A;  2Y6D A;  3B8Z A;  3HDA P;  3I7G A;  3AIG A;  2PJT A;  1XFZ A;  4JP4 A;  1QIA A;  1MMR A;  4GR3 A;  1HFS A;  4DD8 A;  3LQ0 A;  1IAG A;  4XM6 A;  1OS9 A;  1IAB A;  5B5P A;  4A3W A;  3KEK A;  3ELM A;  1R1H A;  1FLS A;  4PKW A;  1JAO A;  3HBU P;  1GO8 P;  2WO8 A;  2OW0 A;  4XCT A;  4PKS A;  1ZP5 A;  4JIJ A;  1KAP P;  1IAA A;  1ZXV A;  2ERQ A;  5L79 A;  3NX7 A;  1BIW A;  4I03 A;  4DV8 A;  5D7W A;  1XFU A;  3LJG A;  3N2V A;  4JA1 A;  4HMA A;  1USN A;  4Q1L A;  4H84 A;  1HFC A;  3K7N A;  1XFY A;  1ZVX A;  3VTG A;  1KUI A;  2E2D A;  3F16 A;  3DWB A;  1UTZ A;  5D1S A;  3KEC A;  3LIR A;  1A85 A;  5D1U A;  1YOU A;  1PWP A;  3CKI A;  1XFX A;  5I3M A;  1PWU A;  3LUM A;  1DMT A;  1Y93 A;  4ZR5 A;  4JQG A;  1IAD A;  3RTT A;  1BUV M;  2X7M A;  4JPA A;  1D7X A;  830C A;  3HDB A;  1K7I A;  1CGF A;  3LQB A;  4IJO A;  3DTI A;  5BPA A;  3U1R A;  2OY2 A;  1O0T A;  3V96 B;  2K2G A;  2L0R A;  3OHO A;  3DTK A; 
#chains in the Genus database with same CATH homology
 2MZE A;  3KME A;  2DW0 A;  1SMP A;  3AYU A;  4XM7 A;  1BQO A;  1D5J A;  3LIL A;  1ATL A;  1Y8J A;  4FXY P;  2D1N A;  1XFV A;  1JJ9 A;  1C7K A;  3KWV C;  1GO7 P;  1UEA A;  1KUK A;  2X3A A;  1SRP A;  2YUF A;  3Q2H A;  4WZV A;  1EUB A;  3BA0 A;  3LEA A;  3Q2G A;  4GWM A;  4GWN A;  5I4O A;  3KEJ A;  2JNP A;  3K7L A;  2DW2 A;  3KRY A;  3P1V A;  2QPJ A;  4PKQ A;  3E8R A;  4AYK A;  1D8F A;  1BQQ M;  3L0T A;  1Y0V A;  4DPE A;  1CXV A;  2OW9 A;  2AIG P;  1MMB A;  4L19 A;  5CUH A;  4PKV A;  456C A;  3DL1 A;  1D8M A;  4WKE A;  1JAP A;  3WV3 A;  3OHL A;  4GR0 A;  1JK3 A;  4ON1 A;  4XM8 A;  2W15 A;  1GE6 A;  2RJP A;  2V4B A;  4H1Q A;  2JSD A;  1JAN A;  2D1O A;  3KHI A;  1QJJ A;  1DTH A;  2J83 A;  1SU3 A;  3P24 A;  3WV1 A;  3N2U A;  3HYG A;  1IAC A;  1YCM A;  1RM8 A;  4J4M A;  1O0Q A;  4GR8 A;  4PKR A;  4L63 A;  1WNI A;  2A8H A;  1Z3J A;  4PKT A;  4GQL A;  3LMC A;  5CXA A;  3L0V A;  1CGL A;  2YB9 A;  3RTS A;  2K9C A;  1CGE A;  4XBH A;  3EHY A;  1AYK A;  1G05 A;  4ILW D;  1BZS A;  4GUY A;  4A7B A;  3LUN A;  2OW2 A;  2JIH A;  3WV2 A;  2JT6 A;  1IAE A;  2MLR A;  1ZXC A;  3EWJ A;  1PWV A;  3UVC A;  1JKY A;  1XUC A;  2X3C A;  1B8Y A;  1BUD A;  1AF0 A;  1OS2 A;  2J0T A;  5I12 A;  1QJI A;  1ND1 A;  4R3V A;  5I0L A;  2SRT A;  2YIG A;  3B92 A;  3F18 A;  4I35 A;  2OVX A;  4WK7 A;  1JIW P;  1KBC A;  1Q3A A;  3DNG A;  2JT5 A;  1QUA A;  1YQY A;  3ZXH A;  2RJQ A;  1EAK A;  2W14 A;  2O3E A;  4H82 A;  2CKI A;  1GXD A;  2ERO A;  4FU4 A;  5I43 A;  2WO9 A;  3I7I A;  1G4K A;  1CK7 A;  4FXQ A;  3HBV P;  3F15 A;  1AKL A;  4DF9 A;  4AXQ A;  1OM8 A;  2MZH A;  3DPE A;  1BKC E;  5LAB A;  1HOV A;  5I2Z A;  4PKU A;  1R1J A;  1QIB A;  4CTH A;  3B2Z A;  5CZM A;  3LJZ A;  2HU6 A;  2I47 A;  5BOY A;  1JIZ A;  4G0D A;  2XS4 A;  1HV5 A;  3LKA A;  1L6J A;  3TSK A;  1SLM A;  3MA2 A;  1CIZ A;  1H71 P;  3EDH A;  1PWW A;  5D3C A;  4IN9 A;  1G49 A;  3SHI A;  4HX3 A;  3LIK A;  1B3D A;  1FBL A;  1OM6 A;  2OVZ A;  1CAQ A;  4WF6 A;  2OY4 A;  5B5O A;  1EB6 A;  2OXU A;  2OI0 A;  3LJT A;  4IUW A;  4FVL A;  1RMZ A;  1GKC A;  1GE5 A;  2DDF A;  3DPF A;  4AIG A;  1XFW A;  2ERP A;  4L6T A;  2USN A;  3KMC A;  3G42 A;  2Y6C A;  2Z2D A;  1G12 A;  1R55 A;  5BOT A;  4AUO A;  2MLS A;  1JAQ A;  3O2X A;  2O36 A;  1SLN A;  1K7G A;  1UTT A;  1C8T A;  1KUF A;  2WOA A;  3EDI A;  1BM6 A;  4WKI A;  2W12 A;  4G9L A;  2OW1 A;  2FV5 A;  1I76 A;  1I73 A;  3EDG A;  2POJ A;  3HY7 A;  2AYK A;  1BKC A;  3TVC A;  1XUD A;  1XUR A;  2KRJ A;  1UMT A;  2DDY A;  1OMJ A;  2E3X A;  3ZVS A;  2X3B A;  2FV9 A;  3HY9 A;  4L7A A;  1OM7 A;  2W13 A;  1AST A;  5D2B A;  2MZI A;  1YP1 A;  3LE9 A;  4GF1 A;  5JMY A;  4EFS A;  1ROS A;  966C A;  5H8X A;  3LGP A;  1R54 A;  1PWQ A;  4H2E A;  1BSW A;  2TCL A;  4H49 A;  1C3I A;  3F1A A;  2W0D A;  3DTE A;  1HTD A;  1QIC A;  2N8R A;  2DW1 A;  1A86 A;  3ZUK A;  1R1I A;  3VI1 A;  1MMQ A;  1CQR A;  1UMS A;  1ZS0 A;  1ZTQ A;  3F17 A;  1OO9 A;  4H30 A;  3USN A;  1BKC I;  3O64 A;  2CLT A;  3F19 A;  2OXZ A;  1S4B P;  1MNC A;  5L7F A;  3HB2 P;  2OXW A;  1I1I P;  4H3X A;  3LK8 A;  1GE7 A;  3TS4 A;  1SAT A;  4QKZ A;  1HY7 A;  2XS3 A;  1GKD A;  3EHX A;  1MMP A;  1J7N A;  1KUH A;  1KUG A;  3DSL A;  1G9K A;  3G5C A;  4H76 A;  1K7Q A;  3EDZ A;  3AYK A;  3GBO A;  1JH1 A;  5D1T A;  1FM1 A;  3TT4 A;  2OZR A;  2Y6D A;  3B8Z A;  3HDA P;  3I7G A;  3AIG A;  2PJT A;  1XFZ A;  4JP4 A;  1QIA A;  1MMR A;  4GR3 A;  1HFS A;  4DD8 A;  3LQ0 A;  1IAG A;  4XM6 A;  1OS9 A;  1IAB A;  5B5P A;  4A3W A;  3KEK A;  3ELM A;  1R1H A;  1FLS A;  4PKW A;  1JAO A;  3HBU P;  1GO8 P;  2WO8 A;  2OW0 A;  4XCT A;  4PKS A;  1ZP5 A;  4JIJ A;  1KAP P;  1IAA A;  1ZXV A;  2ERQ A;  5L79 A;  3NX7 A;  1BIW A;  4I03 A;  4DV8 A;  5D7W A;  1XFU A;  3LJG A;  3N2V A;  4JA1 A;  4HMA A;  1USN A;  4Q1L A;  4H84 A;  1HFC A;  3K7N A;  1XFY A;  1ZVX A;  3VTG A;  1KUI A;  2E2D A;  3F16 A;  3DWB A;  1UTZ A;  5D1S A;  3KEC A;  3LIR A;  1A85 A;  5D1U A;  1YOU A;  1PWP A;  3CKI A;  1XFX A;  5I3M A;  1PWU A;  3LUM A;  1DMT A;  1Y93 A;  4ZR5 A;  4JQG A;  1IAD A;  3RTT A;  1BUV M;  2X7M A;  4JPA A;  1D7X A;  830C A;  3HDB A;  1K7I A;  1CGF A;  3LQB A;  4IJO A;  3DTI A;  5BPA A;  3U1R A;  2OY2 A;  1O0T A;  3V96 B;  2K2G A;  2L0R A;  3OHO A;  3DTK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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