5I43A

Crystal structure of the catalytic domain of mmp-12 in complex with a selective sugar-conjugated triazole-linked carboxylate chelator water-soluble inhibitor (dc32).
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
157
structure length
157
Chain Sequence
PVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHQIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 46
structure length 157
sequence length 157
chains with identical sequence B, C, D
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2016-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 5i43A00
3KMCA 4WF6A 1KAPP 1GE7A 2J0TA 3LE9A 4WKIA 4CTHA 2OY2A 1ASTA 1D8MA 4H2EA 3EHXA 3LUNA 1A85A 3NX7A 4WZVA 1OS2A 4FVLA 5B5OA 5CXAA 1IAGA 5I3MA 3G42A 1BSWA 1CGLA 5LABA 3Q2HA 3TSKA 3I7IA 1FBLA 2MZIA 4XM8A 1USNA 1JJ9A 1GO7P 4GUYA 3SHIA 5JMYA 1J7NA 1WNIA 3B8ZA 1K7IA 2MZHA 3CKIA 1R1HA 2D1NA 1CK7A 1XFYA 2WO8A 4ILWD 1OM6A 2W12A 3EDZA 1JAPA 4ZR5A 2JNPA 1JAQA 4H30A 2OZRA 3HY9A 2K2GA 2W13A 2N8RA 1Y0VA 1JIZA 1SLNA 2MLSA 4QKZA 3TT4A 1OM8A 2Z2DA 2AIGP 1XFVA 4PKQA 2PJTA 4JA1A 1CQRA 5D3CA 1O0TA 2X3AA 1BQQM 1CGFA 3L0VA 1SRPA 1QUAA 3KHIA 3F1AA 5L7FA 3LJGA 1D5JA 3LJZA 1ZVXA 4GWMA 5BOYA 3KWVC 3UVCA 1MNCA 1ZTQA 2OW0A 3OHLA 2RJQA 4PKSA 1G05A 1BM6A 1GKCA 4G0DA 4JIJA 4FXYP 4AUOA 1GXDA 1R1JA 5BPAA 4H3XA 1IABA 1GO8P 1QJIA 4IJOA 1SMPA 5D1UA 2L0RA 3RTTA 1CIZA 2MZEA 3O2XA 4G9LA 1HTDA 1JK3A 1Y8JA 1PWWA 3DNGA 2X7MA 4GQLA 1XUDA 2ERQA 2POJA 1BUVM 3F19A 1HFCA 1KBCA 2DDYA 1CAQA 3EDHA 3KECA 1Y93A 2E2DA 1JANA 2Y6CA 3AIGA 5I12A 2XS4A 2RJPA 1JAOA 2K9CA 5CUHA 2TCLA 1SLMA 4GR8A 5CZMA 1KUIA 1IADA 456CA 2WOAA 1UTZA 1PWUA 3LGPA 4L6TA 3TS4A 3LIKA 2JSDA 3LK8A 4PKVA 4WK7A 1MMRA 2OW2A 2I47A 1CGEA 1R54A 1I76A 4GF1A 1QIAA 3TVCA 1MMQA 3HDBA 4H1QA 3LJTA 3DPFA 3DWBA 1JH1A 1FM1A 4H82A 2JT6A 4AIGA 1AF0A 2OVXA 3HYGA 2OW1A 3EDGA 1JIWP 2OXZA 3F15A 3AYUA 4I35A 3F18A 4FU4A 1IACA 1UTTA 3G5CA 4H49A 1KUGA 3EHYA 4J4MA 3LQ0A 3BA0A 3K7LA 1HV5A 1BZSA 3F16A 1C7KA 1KUKA 3LILA 1KUFA 2HU6A 3F17A 1CXVA 2J83A 1B8YA 2JT5A 2OXWA 5D1SA 1S4BP 3I7GA 1UMTA 1PWVA 3ZXHA 2OXUA 2YB9A 4AXQA 2O36A 1UMSA 5H8XA 4Q1LA 1XFUA 1OS9A 2JIHA 1GE6A 1G12A 1XURA 3VI1A 1ROSA 2X3CA 3KMEA 1EB6A 1KUHA 1QIBA 3N2UA 4DPEA 3HBUP 2V4BA 1XFWA 1K7QA 3WV2A 1K7GA 4H76A 3VTGA 4PKUA 1RMZA 1I73A 2QPJA 4FXQA 3DPEA 5I0LA 3LQBA 1RM8A 3E8RA 3ZUKA 1L6JA 1FLSA 3HDAP 5D2BA 3B92A 4HMAA 5B5PA 1D7XA 3EDIA 5D1TA 1BKCI 3U1RA 1UEAA 1BUDA 2ERPA 1BIWA 1HY7A 4IUWA 1HOVA 3K7NA 1QJJA 3HY7A 3ZVSA 3HBVP 3DSLA 2D1OA 1PWQA 1EUBA 2DW1A 1YP1A 4L63A 1OO9A 4A3WA 2FV9A 1OMJA 1Z3JA 4L19A 4JQGA 5I2ZA 1GKDA 3Q2GA 4HX3A 4PKTA 2SRTA 1G49A 1GE5A 1XFZA 3B2ZA 1C8TA 1Q3AA 3WV3A 3RTSA 1R1IA 3ELMA 1AYKA 4GWNA 2USNA 3L0TA 4GR3A 5I4OA 2FV5A 1ZP5A 3GBOA 4XBHA 3LMCA 4AYKA 3OHOA 5I43A 2W15A 4PKWA 2YIGA 1PWPA 4DV8A 3LEAA 2OY4A 1HFSA 2W0DA 4A7BA 2X3BA 5D7WA 2DW0A 2W14A 1OM7A 4JPAA 4IN9A 3MA2A 1ZS0A 1O0QA 4JP4A 5L79A 1YCMA 1MMPA 1YQYA 3N2VA 1EAKA 3LUMA 3DL1A 3O64A 1ND1A 1BKCA 2DW2A 1QICA 3KEKA 3KEJA 2AYKA 966CA 4GR0A 4H84A 1D8FA 2MLRA 3P24A 2CKIA 1YOUA 3P1VA 2O3EA 1BKCE 1SU3A 1IAAA 2OW9A 3EWJA 4PKRA 1ZXCA 4DD8A 2WO9A 1G9KA 4XM7A 1C3IA 4R3VA 2OI0A 3WV1A 3V96B 1DMTA 3KRYA 1ATLA 2XS3A 1R55A 3LKAA 1XUCA 4I03A 1AKLA 1JKYA 5BOTA 4ON1A 2KRJA 1IAEA 2CLTA 1G4KA 1A86A 1SATA 4XM6A 1ZXVA 1BQOA 3AYKA 1DTHA 2EROA 830CA 2E3XA 3LIRA 2DDFA 1B3DA 2OVZA 2A8HA 1H71P 3HB2P 4WKEA 1MMBA 2Y6DA 4DF9A 4XCTA 1XFXA 1I1IP 3USNA 4EFSA
chains in the Genus database with same CATH superfamily
3KMCA 4WF6A 1KAPP 1GE7A 2J0TA 3LE9A 4WKIA 4CTHA 2OY2A 1ASTA 1D8MA 4H2EA 3EHXA 3LUNA 1A85A 3NX7A 3DTIA 4WZVA 1OS2A 4FVLA 5B5OA 5CXAA 1IAGA 5I3MA 3G42A 1BSWA 1CGLA 1OZ9A 5LABA 3Q2HA 3TSKA 3I7IA 1FBLA 2MZIA 4XM8A 1USNA 1JJ9A 1GO7P 4GUYA 3SHIA 5JMYA 1J7NA 1WNIA 3B8ZA 1K7IA 2MZHA 3CKIA 1R1HA 2D1NA 1CK7A 1XFYA 2WO8A 4ILWD 1OM6A 2W12A 3DTEA 3EDZA 1JAPA 4ZR5A 2JNPA 1JAQA 4H30A 2OZRA 3HY9A 2K2GA 2W13A 2N8RA 1Y0VA 1JIZA 1SLNA 2MLSA 4QKZA 3TT4A 1OM8A 2Z2DA 2AIGP 1XFVA 4PKQA 2PJTA 4JA1A 1CQRA 5D3CA 3DTKA 1O0TA 2X3AA 1BQQM 1CGFA 3L0VA 1SRPA 1QUAA 3KHIA 3F1AA 1XAXA 5L7FA 3LJGA 1D5JA 3LJZA 1ZVXA 4GWMA 5BOYA 3KWVC 3UVCA 1MNCA 1ZTQA 2OW0A 3OHLA 2RJQA 4PKSA 1G05A 1BM6A 1GKCA 4G0DA 4JIJA 4FXYP 4AUOA 1GXDA 1R1JA 5BPAA 4H3XA 1IABA 1GO8P 1QJIA 4IJOA 1SMPA 5D1UA 2L0RA 3RTTA 1CIZA 2MZEA 3O2XA 4G9LA 1HTDA 1JK3A 1Y8JA 1PWWA 3DNGA 2X7MA 4GQLA 1XUDA 2ERQA 2POJA 1BUVM 3F19A 1HFCA 1KBCA 2DDYA 1CAQA 3EDHA 3KECA 1Y93A 2E2DA 1JANA 2Y6CA 3AIGA 5I12A 2XS4A 2RJPA 2YUFA 1JAOA 2K9CA 5CUHA 1TVIA 2TCLA 1SLMA 4GR8A 5CZMA 1KUIA 1IADA 456CA 2WOAA 1UTZA 1PWUA 3LGPA 4L6TA 3TS4A 3LIKA 2JSDA 3LK8A 4PKVA 4WK7A 1MMRA 2OW2A 2I47A 1CGEA 1R54A 1I76A 4GF1A 1QIAA 3TVCA 1MMQA 3HDBA 4H1QA 3LJTA 3DPFA 3DWBA 1JH1A 1FM1A 4H82A 2JT6A 4AIGA 1AF0A 2OVXA 3HYGA 2OW1A 3EDGA 1JIWP 2OXZA 3F15A 3AYUA 4I35A 3F18A 4FU4A 1IACA 1UTTA 3G5CA 4H49A 1KUGA 3EHYA 4J4MA 3LQ0A 3BA0A 3K7LA 1HV5A 1BZSA 3F16A 1C7KA 1KUKA 3LILA 1KUFA 2HU6A 3F17A 1CXVA 2J83A 1B8YA 2JT5A 2OXWA 5D1SA 1S4BP 3I7GA 1UMTA 1PWVA 3ZXHA 2OXUA 2YB9A 4AXQA 2O36A 1UMSA 5H8XA 4Q1LA 1XFUA 1OS9A 2JIHA 1GE6A 1G12A 1XURA 3VI1A 1ROSA 2X3CA 3KMEA 1EB6A 1KUHA 1QIBA 3N2UA 4DPEA 3HBUP 2V4BA 1XFWA 1K7QA 3WV2A 1K7GA 4H76A 3VTGA 4PKUA 1RMZA 1I73A 2QPJA 4FXQA 3DPEA 5I0LA 3LQBA 1RM8A 3E8RA 3ZUKA 1L6JA 1FLSA 3HDAP 5D2BA 3B92A 4HMAA 5B5PA 1D7XA 3EDIA 5D1TA 1BKCI 3U1RA 1UEAA 1BUDA 2ERPA 1BIWA 1HY7A 4IUWA 1HOVA 3K7NA 1QJJA 3HY7A 3ZVSA 3HBVP 3DSLA 2D1OA 1PWQA 1EUBA 2DW1A 1YP1A 4L63A 1OO9A 4A3WA 2FV9A 1OMJA 1Z3JA 4L19A 4JQGA 1XM5A 5I2ZA 1GKDA 3Q2GA 4HX3A 4PKTA 2SRTA 1G49A 1GE5A 1XFZA 3B2ZA 1C8TA 1Q3AA 3WV3A 3RTSA 1R1IA 3ELMA 1AYKA 4GWNA 2USNA 3L0TA 4GR3A 5I4OA 2FV5A 1ZP5A 3GBOA 4L7AA 4XBHA 3LMCA 4AYKA 3OHOA 5I43A 2W15A 4PKWA 2YIGA 1PWPA 4DV8A 3LEAA 2OY4A 1HFSA 2W0DA 4A7BA 2X3BA 5D7WA 2DW0A 2W14A 1OM7A 4JPAA 4IN9A 3MA2A 1ZS0A 1O0QA 4JP4A 5L79A 1YCMA 1MMPA 1YQYA 3N2VA 1EAKA 3LUMA 3DL1A 3O64A 1ND1A 1BKCA 2DW2A 1QICA 3KEKA 3KEJA 2AYKA 966CA 4GR0A 4H84A 1D8FA 2MLRA 3P24A 2CKIA 1YOUA 3P1VA 2O3EA 1BKCE 1SU3A 1IAAA 2OW9A 3EWJA 4PKRA 1ZXCA 4DD8A 2WO9A 1G9KA 4XM7A 1C3IA 4R3VA 2OI0A 3WV1A 3V96B 1DMTA 3KRYA 1ATLA 2XS3A 1R55A 3LKAA 1XUCA 4I03A 1AKLA 1JKYA 5BOTA 4ON1A 2KRJA 1IAEA 2CLTA 1G4KA 1A86A 1SATA 4XM6A 1ZXVA 1BQOA 3AYKA 1DTHA 2EROA 830CA 2E3XA 3LIRA 2DDFA 1B3DA 2OVZA 2A8HA 1H71P 3HB2P 4WKEA 1MMBA 2Y6DA 4DF9A 4XCTA 1XFXA 1I1IP 3USNA 4EFSA
chains in the Genus database with same CATH topology
3KMCA 4WF6A 1KAPP 1GE7A 2J0TA 3LE9A 4WKIA 4CTHA 2OY2A 1ASTA 1D8MA 4H2EA 3EHXA 3LUNA 1A85A 3NX7A 3DTIA 4WZVA 1OS2A 4FVLA 5B5OA 5CXAA 1IAGA 5I3MA 3G42A 1BSWA 1CGLA 5LABA 3Q2HA 3TSKA 3I7IA 1FBLA 2MZIA 4XM8A 1USNA 1JJ9A 1GO7P 4GUYA 3SHIA 5JMYA 1J7NA 1WNIA 3B8ZA 1K7IA 2MZHA 3CKIA 1R1HA 2D1NA 1CK7A 1XFYA 2WO8A 4ILWD 1OM6A 2W12A 3DTEA 3EDZA 1JAPA 4ZR5A 2JNPA 1JAQA 4H30A 2OZRA 3HY9A 2K2GA 2W13A 2N8RA 1Y0VA 1JIZA 1SLNA 2MLSA 4QKZA 3TT4A 1OM8A 2Z2DA 2AIGP 1XFVA 4PKQA 2PJTA 4JA1A 1CQRA 5D3CA 3DTKA 1O0TA 2X3AA 1BQQM 1CGFA 3L0VA 1SRPA 1QUAA 3KHIA 3F1AA 5L7FA 3LJGA 1D5JA 3LJZA 1ZVXA 4GWMA 5BOYA 3KWVC 3UVCA 1MNCA 1ZTQA 2OW0A 3OHLA 2RJQA 4PKSA 1G05A 1BM6A 1GKCA 4G0DA 4JIJA 4FXYP 4AUOA 1GXDA 1R1JA 5BPAA 4H3XA 1IABA 1GO8P 1QJIA 4IJOA 1SMPA 5D1UA 2L0RA 3RTTA 1CIZA 2MZEA 3O2XA 4G9LA 1HTDA 1JK3A 1Y8JA 1PWWA 3DNGA 2X7MA 4GQLA 1XUDA 2ERQA 2POJA 1BUVM 3F19A 1HFCA 1KBCA 2DDYA 1CAQA 3EDHA 3KECA 1Y93A 2E2DA 1JANA 2Y6CA 3AIGA 5I12A 2XS4A 2RJPA 2YUFA 1JAOA 2K9CA 5CUHA 2TCLA 1SLMA 4GR8A 5CZMA 1KUIA 1IADA 456CA 2WOAA 1UTZA 1PWUA 3LGPA 4L6TA 3TS4A 3LIKA 2JSDA 3LK8A 4PKVA 4WK7A 1MMRA 2OW2A 2I47A 1CGEA 1R54A 1I76A 4GF1A 1QIAA 3TVCA 1MMQA 3HDBA 4H1QA 3LJTA 3DPFA 3DWBA 1JH1A 1FM1A 4H82A 2JT6A 4AIGA 1AF0A 2OVXA 3HYGA 2OW1A 3EDGA 1JIWP 2OXZA 3F15A 3AYUA 4I35A 3F18A 4FU4A 1IACA 1UTTA 3G5CA 4H49A 1KUGA 3EHYA 4J4MA 3LQ0A 3BA0A 3K7LA 1HV5A 1BZSA 3F16A 1C7KA 1KUKA 3LILA 1KUFA 2HU6A 3F17A 1CXVA 2J83A 1B8YA 2JT5A 2OXWA 5D1SA 1S4BP 3I7GA 1UMTA 1PWVA 3ZXHA 2OXUA 2YB9A 4AXQA 2O36A 1UMSA 5H8XA 4Q1LA 1XFUA 1OS9A 2JIHA 1GE6A 1G12A 1XURA 3VI1A 1ROSA 2X3CA 3KMEA 1EB6A 1KUHA 1QIBA 3N2UA 4DPEA 3HBUP 2V4BA 1XFWA 1K7QA 3WV2A 1K7GA 4H76A 3VTGA 4PKUA 1RMZA 1I73A 2QPJA 4FXQA 3DPEA 5I0LA 3LQBA 1RM8A 3E8RA 3ZUKA 1L6JA 1FLSA 3HDAP 5D2BA 3B92A 4HMAA 5B5PA 1D7XA 3EDIA 5D1TA 1BKCI 3U1RA 1UEAA 1BUDA 2ERPA 1BIWA 1HY7A 4IUWA 1HOVA 3K7NA 1QJJA 3HY7A 3ZVSA 3HBVP 3DSLA 2D1OA 1PWQA 1EUBA 2DW1A 1YP1A 4L63A 1OO9A 4A3WA 2FV9A 1OMJA 1Z3JA 4L19A 4JQGA 5I2ZA 1GKDA 3Q2GA 4HX3A 4PKTA 2SRTA 1G49A 1GE5A 1XFZA 3B2ZA 1C8TA 1Q3AA 3WV3A 3RTSA 1R1IA 3ELMA 1AYKA 4GWNA 2USNA 3L0TA 4GR3A 5I4OA 2FV5A 1ZP5A 3GBOA 4L7AA 4XBHA 3LMCA 4AYKA 3OHOA 5I43A 2W15A 4PKWA 2YIGA 1PWPA 4DV8A 3LEAA 2OY4A 1HFSA 2W0DA 4A7BA 2X3BA 5D7WA 2DW0A 2W14A 1OM7A 4JPAA 4IN9A 3MA2A 1ZS0A 1O0QA 4JP4A 5L79A 1YCMA 1MMPA 1YQYA 3N2VA 1EAKA 3LUMA 3DL1A 3O64A 1ND1A 1BKCA 2DW2A 1QICA 3KEKA 3KEJA 2AYKA 966CA 4GR0A 4H84A 1D8FA 2MLRA 3P24A 2CKIA 1YOUA 3P1VA 2O3EA 1BKCE 1SU3A 1IAAA 2OW9A 3EWJA 4PKRA 1ZXCA 4DD8A 2WO9A 1G9KA 4XM7A 1C3IA 4R3VA 2OI0A 3WV1A 3V96B 1DMTA 3KRYA 1ATLA 2XS3A 1R55A 3LKAA 1XUCA 4I03A 1AKLA 1JKYA 5BOTA 4ON1A 2KRJA 1IAEA 2CLTA 1G4KA 1A86A 1SATA 4XM6A 1ZXVA 1BQOA 3AYKA 1DTHA 2EROA 830CA 2E3XA 3LIRA 2DDFA 1B3DA 2OVZA 2A8HA 1H71P 3HB2P 4WKEA 1MMBA 2Y6DA 4DF9A 4XCTA 1XFXA 1I1IP 3USNA 4EFSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KMC A;  4WF6 A;  1KAP P;  1GE7 A;  2J0T A;  3LE9 A;  4WKI A;  4CTH A;  2OY2 A;  1AST A;  1D8M A;  4H2E A;  3EHX A;  3LUN A;  1A85 A;  3NX7 A;  4WZV A;  1OS2 A;  4FVL A;  5B5O A;  5CXA A;  1IAG A;  5I3M A;  3G42 A;  1BSW A;  1CGL A;  5LAB A;  3Q2H A;  3TSK A;  3I7I A;  1FBL A;  2MZI A;  4XM8 A;  1USN A;  1JJ9 A;  1GO7 P;  4GUY A;  3SHI A;  5JMY A;  1J7N A;  1WNI A;  3B8Z A;  1K7I A;  2MZH A;  3CKI A;  1R1H A;  2D1N A;  1CK7 A;  1XFY A;  2WO8 A;  4ILW D;  1OM6 A;  2W12 A;  3EDZ A;  1JAP A;  4ZR5 A;  2JNP A;  1JAQ A;  4H30 A;  2OZR A;  3HY9 A;  2K2G A;  2W13 A;  2N8R A;  1Y0V A;  1JIZ A;  1SLN A;  2MLS A;  4QKZ A;  3TT4 A;  1OM8 A;  2Z2D A;  2AIG P;  1XFV A;  4PKQ A;  2PJT A;  4JA1 A;  1CQR A;  5D3C A;  1O0T A;  2X3A A;  1BQQ M;  1CGF A;  3L0V A;  1SRP A;  1QUA A;  3KHI A;  3F1A A;  5L7F A;  3LJG A;  1D5J A;  3LJZ A;  1ZVX A;  4GWM A;  5BOY A;  3KWV C;  3UVC A;  1MNC A;  1ZTQ A;  2OW0 A;  3OHL A;  2RJQ A;  4PKS A;  1G05 A;  1BM6 A;  1GKC A;  4G0D A;  4JIJ A;  4FXY P;  4AUO A;  1GXD A;  1R1J A;  5BPA A;  4H3X A;  1IAB A;  1GO8 P;  1QJI A;  4IJO A;  1SMP A;  5D1U A;  2L0R A;  3RTT A;  1CIZ A;  2MZE A;  3O2X A;  4G9L A;  1HTD A;  1JK3 A;  1Y8J A;  1PWW A;  3DNG A;  2X7M A;  4GQL A;  1XUD A;  2ERQ A;  2POJ A;  1BUV M;  3F19 A;  1HFC A;  1KBC A;  2DDY A;  1CAQ A;  3EDH A;  3KEC A;  1Y93 A;  2E2D A;  1JAN A;  2Y6C A;  3AIG A;  5I12 A;  2XS4 A;  2RJP A;  1JAO A;  2K9C A;  5CUH A;  2TCL A;  1SLM A;  4GR8 A;  5CZM A;  1KUI A;  1IAD A;  456C A;  2WOA A;  1UTZ A;  1PWU A;  3LGP A;  4L6T A;  3TS4 A;  3LIK A;  2JSD A;  3LK8 A;  4PKV A;  4WK7 A;  1MMR A;  2OW2 A;  2I47 A;  1CGE A;  1R54 A;  1I76 A;  4GF1 A;  1QIA A;  3TVC A;  1MMQ A;  3HDB A;  4H1Q A;  3LJT A;  3DPF A;  3DWB A;  1JH1 A;  1FM1 A;  4H82 A;  2JT6 A;  4AIG A;  1AF0 A;  2OVX A;  3HYG A;  2OW1 A;  3EDG A;  1JIW P;  2OXZ A;  3F15 A;  3AYU A;  4I35 A;  3F18 A;  4FU4 A;  1IAC A;  1UTT A;  3G5C A;  4H49 A;  1KUG A;  3EHY A;  4J4M A;  3LQ0 A;  3BA0 A;  3K7L A;  1HV5 A;  1BZS A;  3F16 A;  1C7K A;  1KUK A;  3LIL A;  1KUF A;  2HU6 A;  3F17 A;  1CXV A;  2J83 A;  1B8Y A;  2JT5 A;  2OXW A;  5D1S A;  1S4B P;  3I7G A;  1UMT A;  1PWV A;  3ZXH A;  2OXU A;  2YB9 A;  4AXQ A;  2O36 A;  1UMS A;  5H8X A;  4Q1L A;  1XFU A;  1OS9 A;  2JIH A;  1GE6 A;  1G12 A;  1XUR A;  3VI1 A;  1ROS A;  2X3C A;  3KME A;  1EB6 A;  1KUH A;  1QIB A;  3N2U A;  4DPE A;  3HBU P;  2V4B A;  1XFW A;  1K7Q A;  3WV2 A;  1K7G A;  4H76 A;  3VTG A;  4PKU A;  1RMZ A;  1I73 A;  2QPJ A;  4FXQ A;  3DPE A;  5I0L A;  3LQB A;  1RM8 A;  3E8R A;  3ZUK A;  1L6J A;  1FLS A;  3HDA P;  5D2B A;  3B92 A;  4HMA A;  5B5P A;  1D7X A;  3EDI A;  5D1T A;  1BKC I;  3U1R A;  1UEA A;  1BUD A;  2ERP A;  1BIW A;  1HY7 A;  4IUW A;  1HOV A;  3K7N A;  1QJJ A;  3HY7 A;  3ZVS A;  3HBV P;  3DSL A;  2D1O A;  1PWQ A;  1EUB A;  2DW1 A;  1YP1 A;  4L63 A;  1OO9 A;  4A3W A;  2FV9 A;  1OMJ A;  1Z3J A;  4L19 A;  4JQG A;  5I2Z A;  1GKD A;  3Q2G A;  4HX3 A;  4PKT A;  2SRT A;  1G49 A;  1GE5 A;  1XFZ A;  3B2Z A;  1C8T A;  1Q3A A;  3WV3 A;  3RTS A;  1R1I A;  3ELM A;  1AYK A;  4GWN A;  2USN A;  3L0T A;  4GR3 A;  5I4O A;  2FV5 A;  1ZP5 A;  3GBO A;  4XBH A;  3LMC A;  4AYK A;  3OHO A;  5I43 A;  2W15 A;  4PKW A;  2YIG A;  1PWP A;  4DV8 A;  3LEA A;  2OY4 A;  1HFS A;  2W0D A;  4A7B A;  2X3B A;  5D7W A;  2DW0 A;  2W14 A;  1OM7 A;  4JPA A;  4IN9 A;  3MA2 A;  1ZS0 A;  1O0Q A;  4JP4 A;  5L79 A;  1YCM A;  1MMP A;  1YQY A;  3N2V A;  1EAK A;  3LUM A;  3DL1 A;  3O64 A;  1ND1 A;  1BKC A;  2DW2 A;  1QIC A;  3KEK A;  3KEJ A;  2AYK A;  966C A;  4GR0 A;  4H84 A;  1D8F A;  2MLR A;  3P24 A;  2CKI A;  1YOU A;  3P1V A;  2O3E A;  1BKC E;  1SU3 A;  1IAA A;  2OW9 A;  3EWJ A;  4PKR A;  1ZXC A;  4DD8 A;  2WO9 A;  1G9K A;  4XM7 A;  1C3I A;  4R3V A;  2OI0 A;  3WV1 A;  3V96 B;  1DMT A;  3KRY A;  1ATL A;  2XS3 A;  1R55 A;  3LKA A;  1XUC A;  4I03 A;  1AKL A;  1JKY A;  5BOT A;  4ON1 A;  2KRJ A;  1IAE A;  2CLT A;  1G4K A;  1A86 A;  1SAT A;  4XM6 A;  1ZXV A;  1BQO A;  3AYK A;  1DTH A;  2ERO A;  830C A;  2E3X A;  3LIR A;  2DDF A;  1B3D A;  2OVZ A;  2A8H A;  1H71 P;  3HB2 P;  4WKE A;  1MMB A;  2Y6D A;  4DF9 A;  4XCT A;  1XFX A;  1I1I P;  3USN A;  4EFS A; 
#chains in the Genus database with same CATH topology
 3KMC A;  4WF6 A;  1KAP P;  1GE7 A;  2J0T A;  3LE9 A;  4WKI A;  4CTH A;  2OY2 A;  1AST A;  1D8M A;  4H2E A;  3EHX A;  3LUN A;  1A85 A;  3NX7 A;  3DTI A;  4WZV A;  1OS2 A;  4FVL A;  5B5O A;  5CXA A;  1IAG A;  5I3M A;  3G42 A;  1BSW A;  1CGL A;  1OZ9 A;  5LAB A;  3Q2H A;  3TSK A;  3I7I A;  1FBL A;  2MZI A;  4XM8 A;  1USN A;  1JJ9 A;  1GO7 P;  4GUY A;  3SHI A;  5JMY A;  1J7N A;  1WNI A;  3B8Z A;  1K7I A;  2MZH A;  3CKI A;  1R1H A;  2D1N A;  1CK7 A;  1XFY A;  2WO8 A;  4ILW D;  1OM6 A;  2W12 A;  3DTE A;  3EDZ A;  1JAP A;  4ZR5 A;  2JNP A;  1JAQ A;  4H30 A;  2OZR A;  3HY9 A;  2K2G A;  2W13 A;  2N8R A;  1Y0V A;  1JIZ A;  1SLN A;  2MLS A;  4QKZ A;  3TT4 A;  1OM8 A;  2Z2D A;  2AIG P;  1XFV A;  4PKQ A;  2PJT A;  4JA1 A;  1CQR A;  5D3C A;  3DTK A;  1O0T A;  2X3A A;  1BQQ M;  1CGF A;  3L0V A;  1SRP A;  1QUA A;  3KHI A;  3F1A A;  1XAX A;  5L7F A;  3LJG A;  1D5J A;  3LJZ A;  1ZVX A;  4GWM A;  5BOY A;  3KWV C;  3UVC A;  1MNC A;  1ZTQ A;  2OW0 A;  3OHL A;  2RJQ A;  4PKS A;  1G05 A;  1BM6 A;  1GKC A;  4G0D A;  4JIJ A;  4FXY P;  4AUO A;  1GXD A;  1R1J A;  5BPA A;  4H3X A;  1IAB A;  1GO8 P;  1QJI A;  4IJO A;  1SMP A;  5D1U A;  2L0R A;  3RTT A;  1CIZ A;  2MZE A;  3O2X A;  4G9L A;  1HTD A;  1JK3 A;  1Y8J A;  1PWW A;  3DNG A;  2X7M A;  4GQL A;  1XUD A;  2ERQ A;  2POJ A;  1BUV M;  3F19 A;  1HFC A;  1KBC A;  2DDY A;  1CAQ A;  3EDH A;  3KEC A;  1Y93 A;  2E2D A;  1JAN A;  2Y6C A;  3AIG A;  5I12 A;  2XS4 A;  2RJP A;  2YUF A;  1JAO A;  2K9C A;  5CUH A;  1TVI A;  2TCL A;  1SLM A;  4GR8 A;  5CZM A;  1KUI A;  1IAD A;  456C A;  2WOA A;  1UTZ A;  1PWU A;  3LGP A;  4L6T A;  3TS4 A;  3LIK A;  2JSD A;  3LK8 A;  4PKV A;  4WK7 A;  1MMR A;  2OW2 A;  2I47 A;  1CGE A;  1R54 A;  1I76 A;  4GF1 A;  1QIA A;  3TVC A;  1MMQ A;  3HDB A;  4H1Q A;  3LJT A;  3DPF A;  3DWB A;  1JH1 A;  1FM1 A;  4H82 A;  2JT6 A;  4AIG A;  1AF0 A;  2OVX A;  3HYG A;  2OW1 A;  3EDG A;  1JIW P;  2OXZ A;  3F15 A;  3AYU A;  4I35 A;  3F18 A;  4FU4 A;  1IAC A;  1UTT A;  3G5C A;  4H49 A;  1KUG A;  3EHY A;  4J4M A;  3LQ0 A;  3BA0 A;  3K7L A;  1HV5 A;  1BZS A;  3F16 A;  1C7K A;  1KUK A;  3LIL A;  1KUF A;  2HU6 A;  3F17 A;  1CXV A;  2J83 A;  1B8Y A;  2JT5 A;  2OXW A;  5D1S A;  1S4B P;  3I7G A;  1UMT A;  1PWV A;  3ZXH A;  2OXU A;  2YB9 A;  4AXQ A;  2O36 A;  1UMS A;  5H8X A;  4Q1L A;  1XFU A;  1OS9 A;  2JIH A;  1GE6 A;  1G12 A;  1XUR A;  3VI1 A;  1ROS A;  2X3C A;  3KME A;  1EB6 A;  1KUH A;  1QIB A;  3N2U A;  4DPE A;  3HBU P;  2V4B A;  1XFW A;  1K7Q A;  3WV2 A;  1K7G A;  4H76 A;  3VTG A;  4PKU A;  1RMZ A;  1I73 A;  2QPJ A;  4FXQ A;  3DPE A;  5I0L A;  3LQB A;  1RM8 A;  3E8R A;  3ZUK A;  1L6J A;  1FLS A;  3HDA P;  5D2B A;  3B92 A;  4HMA A;  5B5P A;  1D7X A;  3EDI A;  5D1T A;  1BKC I;  3U1R A;  1UEA A;  1BUD A;  2ERP A;  1BIW A;  1HY7 A;  4IUW A;  1HOV A;  3K7N A;  1QJJ A;  3HY7 A;  3ZVS A;  3HBV P;  3DSL A;  2D1O A;  1PWQ A;  1EUB A;  2DW1 A;  1YP1 A;  4L63 A;  1OO9 A;  4A3W A;  2FV9 A;  1OMJ A;  1Z3J A;  4L19 A;  4JQG A;  1XM5 A;  5I2Z A;  1GKD A;  3Q2G A;  4HX3 A;  4PKT A;  2SRT A;  1G49 A;  1GE5 A;  1XFZ A;  3B2Z A;  1C8T A;  1Q3A A;  3WV3 A;  3RTS A;  1R1I A;  3ELM A;  1AYK A;  4GWN A;  2USN A;  3L0T A;  4GR3 A;  5I4O A;  2FV5 A;  1ZP5 A;  3GBO A;  4L7A A;  4XBH A;  3LMC A;  4AYK A;  3OHO A;  5I43 A;  2W15 A;  4PKW A;  2YIG A;  1PWP A;  4DV8 A;  3LEA A;  2OY4 A;  1HFS A;  2W0D A;  4A7B A;  2X3B A;  5D7W A;  2DW0 A;  2W14 A;  1OM7 A;  4JPA A;  4IN9 A;  3MA2 A;  1ZS0 A;  1O0Q A;  4JP4 A;  5L79 A;  1YCM A;  1MMP A;  1YQY A;  3N2V A;  1EAK A;  3LUM A;  3DL1 A;  3O64 A;  1ND1 A;  1BKC A;  2DW2 A;  1QIC A;  3KEK A;  3KEJ A;  2AYK A;  966C A;  4GR0 A;  4H84 A;  1D8F A;  2MLR A;  3P24 A;  2CKI A;  1YOU A;  3P1V A;  2O3E A;  1BKC E;  1SU3 A;  1IAA A;  2OW9 A;  3EWJ A;  4PKR A;  1ZXC A;  4DD8 A;  2WO9 A;  1G9K A;  4XM7 A;  1C3I A;  4R3V A;  2OI0 A;  3WV1 A;  3V96 B;  1DMT A;  3KRY A;  1ATL A;  2XS3 A;  1R55 A;  3LKA A;  1XUC A;  4I03 A;  1AKL A;  1JKY A;  5BOT A;  4ON1 A;  2KRJ A;  1IAE A;  2CLT A;  1G4K A;  1A86 A;  1SAT A;  4XM6 A;  1ZXV A;  1BQO A;  3AYK A;  1DTH A;  2ERO A;  830C A;  2E3X A;  3LIR A;  2DDF A;  1B3D A;  2OVZ A;  2A8H A;  1H71 P;  3HB2 P;  4WKE A;  1MMB A;  2Y6D A;  4DF9 A;  4XCT A;  1XFX A;  1I1I P;  3USN A;  4EFS A; 
#chains in the Genus database with same CATH homology
 3KMC A;  4WF6 A;  1KAP P;  1GE7 A;  2J0T A;  3LE9 A;  4WKI A;  4CTH A;  2OY2 A;  1AST A;  1D8M A;  4H2E A;  3EHX A;  3LUN A;  1A85 A;  3NX7 A;  3DTI A;  4WZV A;  1OS2 A;  4FVL A;  5B5O A;  5CXA A;  1IAG A;  5I3M A;  3G42 A;  1BSW A;  1CGL A;  5LAB A;  3Q2H A;  3TSK A;  3I7I A;  1FBL A;  2MZI A;  4XM8 A;  1USN A;  1JJ9 A;  1GO7 P;  4GUY A;  3SHI A;  5JMY A;  1J7N A;  1WNI A;  3B8Z A;  1K7I A;  2MZH A;  3CKI A;  1R1H A;  2D1N A;  1CK7 A;  1XFY A;  2WO8 A;  4ILW D;  1OM6 A;  2W12 A;  3DTE A;  3EDZ A;  1JAP A;  4ZR5 A;  2JNP A;  1JAQ A;  4H30 A;  2OZR A;  3HY9 A;  2K2G A;  2W13 A;  2N8R A;  1Y0V A;  1JIZ A;  1SLN A;  2MLS A;  4QKZ A;  3TT4 A;  1OM8 A;  2Z2D A;  2AIG P;  1XFV A;  4PKQ A;  2PJT A;  4JA1 A;  1CQR A;  5D3C A;  3DTK A;  1O0T A;  2X3A A;  1BQQ M;  1CGF A;  3L0V A;  1SRP A;  1QUA A;  3KHI A;  3F1A A;  5L7F A;  3LJG A;  1D5J A;  3LJZ A;  1ZVX A;  4GWM A;  5BOY A;  3KWV C;  3UVC A;  1MNC A;  1ZTQ A;  2OW0 A;  3OHL A;  2RJQ A;  4PKS A;  1G05 A;  1BM6 A;  1GKC A;  4G0D A;  4JIJ A;  4FXY P;  4AUO A;  1GXD A;  1R1J A;  5BPA A;  4H3X A;  1IAB A;  1GO8 P;  1QJI A;  4IJO A;  1SMP A;  5D1U A;  2L0R A;  3RTT A;  1CIZ A;  2MZE A;  3O2X A;  4G9L A;  1HTD A;  1JK3 A;  1Y8J A;  1PWW A;  3DNG A;  2X7M A;  4GQL A;  1XUD A;  2ERQ A;  2POJ A;  1BUV M;  3F19 A;  1HFC A;  1KBC A;  2DDY A;  1CAQ A;  3EDH A;  3KEC A;  1Y93 A;  2E2D A;  1JAN A;  2Y6C A;  3AIG A;  5I12 A;  2XS4 A;  2RJP A;  2YUF A;  1JAO A;  2K9C A;  5CUH A;  2TCL A;  1SLM A;  4GR8 A;  5CZM A;  1KUI A;  1IAD A;  456C A;  2WOA A;  1UTZ A;  1PWU A;  3LGP A;  4L6T A;  3TS4 A;  3LIK A;  2JSD A;  3LK8 A;  4PKV A;  4WK7 A;  1MMR A;  2OW2 A;  2I47 A;  1CGE A;  1R54 A;  1I76 A;  4GF1 A;  1QIA A;  3TVC A;  1MMQ A;  3HDB A;  4H1Q A;  3LJT A;  3DPF A;  3DWB A;  1JH1 A;  1FM1 A;  4H82 A;  2JT6 A;  4AIG A;  1AF0 A;  2OVX A;  3HYG A;  2OW1 A;  3EDG A;  1JIW P;  2OXZ A;  3F15 A;  3AYU A;  4I35 A;  3F18 A;  4FU4 A;  1IAC A;  1UTT A;  3G5C A;  4H49 A;  1KUG A;  3EHY A;  4J4M A;  3LQ0 A;  3BA0 A;  3K7L A;  1HV5 A;  1BZS A;  3F16 A;  1C7K A;  1KUK A;  3LIL A;  1KUF A;  2HU6 A;  3F17 A;  1CXV A;  2J83 A;  1B8Y A;  2JT5 A;  2OXW A;  5D1S A;  1S4B P;  3I7G A;  1UMT A;  1PWV A;  3ZXH A;  2OXU A;  2YB9 A;  4AXQ A;  2O36 A;  1UMS A;  5H8X A;  4Q1L A;  1XFU A;  1OS9 A;  2JIH A;  1GE6 A;  1G12 A;  1XUR A;  3VI1 A;  1ROS A;  2X3C A;  3KME A;  1EB6 A;  1KUH A;  1QIB A;  3N2U A;  4DPE A;  3HBU P;  2V4B A;  1XFW A;  1K7Q A;  3WV2 A;  1K7G A;  4H76 A;  3VTG A;  4PKU A;  1RMZ A;  1I73 A;  2QPJ A;  4FXQ A;  3DPE A;  5I0L A;  3LQB A;  1RM8 A;  3E8R A;  3ZUK A;  1L6J A;  1FLS A;  3HDA P;  5D2B A;  3B92 A;  4HMA A;  5B5P A;  1D7X A;  3EDI A;  5D1T A;  1BKC I;  3U1R A;  1UEA A;  1BUD A;  2ERP A;  1BIW A;  1HY7 A;  4IUW A;  1HOV A;  3K7N A;  1QJJ A;  3HY7 A;  3ZVS A;  3HBV P;  3DSL A;  2D1O A;  1PWQ A;  1EUB A;  2DW1 A;  1YP1 A;  4L63 A;  1OO9 A;  4A3W A;  2FV9 A;  1OMJ A;  1Z3J A;  4L19 A;  4JQG A;  5I2Z A;  1GKD A;  3Q2G A;  4HX3 A;  4PKT A;  2SRT A;  1G49 A;  1GE5 A;  1XFZ A;  3B2Z A;  1C8T A;  1Q3A A;  3WV3 A;  3RTS A;  1R1I A;  3ELM A;  1AYK A;  4GWN A;  2USN A;  3L0T A;  4GR3 A;  5I4O A;  2FV5 A;  1ZP5 A;  3GBO A;  4L7A A;  4XBH A;  3LMC A;  4AYK A;  3OHO A;  5I43 A;  2W15 A;  4PKW A;  2YIG A;  1PWP A;  4DV8 A;  3LEA A;  2OY4 A;  1HFS A;  2W0D A;  4A7B A;  2X3B A;  5D7W A;  2DW0 A;  2W14 A;  1OM7 A;  4JPA A;  4IN9 A;  3MA2 A;  1ZS0 A;  1O0Q A;  4JP4 A;  5L79 A;  1YCM A;  1MMP A;  1YQY A;  3N2V A;  1EAK A;  3LUM A;  3DL1 A;  3O64 A;  1ND1 A;  1BKC A;  2DW2 A;  1QIC A;  3KEK A;  3KEJ A;  2AYK A;  966C A;  4GR0 A;  4H84 A;  1D8F A;  2MLR A;  3P24 A;  2CKI A;  1YOU A;  3P1V A;  2O3E A;  1BKC E;  1SU3 A;  1IAA A;  2OW9 A;  3EWJ A;  4PKR A;  1ZXC A;  4DD8 A;  2WO9 A;  1G9K A;  4XM7 A;  1C3I A;  4R3V A;  2OI0 A;  3WV1 A;  3V96 B;  1DMT A;  3KRY A;  1ATL A;  2XS3 A;  1R55 A;  3LKA A;  1XUC A;  4I03 A;  1AKL A;  1JKY A;  5BOT A;  4ON1 A;  2KRJ A;  1IAE A;  2CLT A;  1G4K A;  1A86 A;  1SAT A;  4XM6 A;  1ZXV A;  1BQO A;  3AYK A;  1DTH A;  2ERO A;  830C A;  2E3X A;  3LIR A;  2DDF A;  1B3D A;  2OVZ A;  2A8H A;  1H71 P;  3HB2 P;  4WKE A;  1MMB A;  2Y6D A;  4DF9 A;  4XCT A;  1XFX A;  1I1I P;  3USN A;  4EFS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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