5I43A

Crystal structure of the catalytic domain of mmp-12 in complex with a selective sugar-conjugated triazole-linked carboxylate chelator water-soluble inhibitor (dc32).
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
157
structure length
157
Chain Sequence
PVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHQIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Homo sapiens
publication title Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors.
pubmed doi rcsb
molecule keywords Macrophage metalloelastase
total genus 46
structure length 157
sequence length 157
chains with identical sequence B, C, D
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2016-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 5i43A00
1UTTA 4G9LA 3O2XA 1BQOA 3LIKA 2W12A 4H30A 3B2ZA 4WKEA 1ZTQA 3OHLA 4H49A 2DW2A 2QPJA 1CIZA 1PWUA 3DPEA 1O0TA 1QJJA 5JMYA 3EDZA 1KUHA 2ERPA 1GO8P 4QKZA 1XFXA 3KWVC 3DPFA 4DV8A 1Z3JA 5D2BA 4JIJA 2W0DA 1IAGA 4CTHA 4JQGA 3AYUA 5I2ZA 2A8HA 1D7XA 1FBLA 5BOYA 4FXQA 4L63A 2CKIA 1FLSA 4WK7A 1GKDA 1IABA 1PWWA 4HX3A 3AIGA 1SU3A 1ZVXA 1HOVA 4J4MA 3E8RA 1GO7P 1ROSA 1GXDA 2MLRA 2OI0A 5I12A 1O0QA 3WV2A 1OM8A 3KECA 2XS4A 1R55A 1ZXVA 1HTDA 2K9CA 2OVXA 1XURA 3Q2GA 3DSLA 1S4BP 2OY4A 4PKVA 4WKIA 1CGLA 1IADA 1JIWP 3DNGA 1BIWA 1BKCI 3VTGA 3ZVSA 1ASTA 1OO9A 3LUNA 3EWJA 3LKAA 4XM8A 1PWPA 2X3CA 1UTZA 5H8XA 1OM6A 1BKCE 4ZR5A 1ATLA 1JH1A 2DW0A 4A7BA 1KUIA 2FV5A 2KRJA 3BA0A 1R1JA 3K7LA 4I03A 5I3MA 2O3EA 3LUMA 2RJPA 1CGEA 3RTSA 2W13A 2YB9A 4H2EA 2PJTA 1EUBA 1IAEA 1CQRA 1YQYA 4FVLA 4WF6A 456CA 5D1SA 4AIGA 3EDGA 2AIGP 1MNCA 5I43A 3F17A 4JP4A 3L0VA 1G49A 5D1UA 3HBUP 5D1TA 3USNA 4GR8A 1JJ9A 2OW0A 4GWMA 4AYKA 3KEKA 2AYKA 1JAPA 2POJA 3HDAP 1DMTA 2E3XA 3TS4A 4XCTA 2OZRA 3ELMA 3L0TA 1RMZA 1QIAA 1XUDA 1Y93A 4ILWD 2MZEA 3I7GA 3G42A 3ZXHA 4L6TA 4WZVA 1QUAA 4GR3A 1JAOA 3GBOA 3EDIA 3P24A 1XFYA 1GE7A 4DF9A 5CZMA 1OM7A 4Q1LA 3LJTA 1OMJA 2XS3A 4AXQA 1IACA 1BKCA 1HFCA 5L79A 3ZUKA 4H84A 3CKIA 2MZIA 2J83A 2L0RA 4L19A 1MMQA 4JPAA 3V96B 3HY7A 4R3VA 3B92A 4PKUA 2WO8A 2DW1A 5CXAA 1SRPA 2O36A 3LILA 1USNA 1UMSA 1HY7A 2Y6DA 1XFVA 2WO9A 1HFSA 1R54A 1BUVM 1ZXCA 1JKYA 1JIZA 1AF0A 1QIBA 3KMEA 3HYGA 4FU4A 1OS9A 3LIRA 2D1NA 1YCMA 2W15A 4GWNA 4GR0A 5BOTA 1K7GA 5B5PA 1XFUA 4DPEA 4JA1A 1D5JA 4DD8A 2JIHA 4XBHA 2DDYA 3WV3A 2JT5A 2JSDA 3HBVP 3OHOA 1EAKA 2OY2A 4G0DA 2X3BA 3UVCA 5B5OA 2ERQA 2K2GA 3LJGA 1Y0VA 1JK3A 1CAQA 2V4BA 5LABA 3EHYA 1MMRA 2YIGA 1JAQA 3Q2HA 4HMAA 1C7KA 1XUCA 4IUWA 3VI1A 2FV9A 1Q3AA 1XFZA 1J7NA 1A86A 966CA 5D7WA 1OS2A 1B3DA 2JT6A 1BSWA 3DL1A 1YP1A 3I7IA 1AYKA 1BM6A 2N8RA 1KBCA 2X3AA 1SATA 3G5CA 3MA2A 5I0LA 1CXVA 3N2UA 1EB6A 4FXYP 1IAAA 3LK8A 1CK7A 3F19A 4EFSA 1CGFA 1PWQA 1WNIA 3B8ZA 2OXZA 1UMTA 2HU6A 3HDBA 1FM1A 2OW9A 1HV5A 4IN9A 1I76A 2W14A 1A85A 3O64A 1R1IA 1L6JA 1GE6A 1ZS0A 2OVZA 3SHIA 3LE9A 2USNA 3LEAA 2OW2A 3WV1A 3HY9A 4AUOA 1KUFA 4XM7A 1C3IA 3EHXA 3K7NA 5BPAA 1H71P 1BQQM 1K7IA 1KUGA 3F18A 4PKTA 1D8MA 1G12A 1G05A 1YOUA 4GF1A 3EDHA 1SLMA 4PKQA 3HB2P 3KEJA 5D3CA 1GE5A 4PKWA 1R1HA 1JANA 4PKSA 1ZP5A 1RM8A 1KAPP 3F15A 1C8TA 1BZSA 4GUYA 2OXWA 1QJIA 2RJQA 3RTTA 2J0TA 830CA 3AYKA 2X7MA 3U1RA 1DTHA 4XM6A 3NX7A 4GQLA 2Z2DA 2OXUA 4H1QA 1BUDA 1G9KA 5CUHA 3TT4A 4H76A 1GKCA 1AKLA 1MMBA 3LJZA 2D1OA 4PKRA 1SLNA 3F1AA 3P1VA 1ND1A 2MLSA 1K7QA 2MZHA 2Y6CA 1XFWA 3KHIA 3KMCA 1I1IP 4IJOA 2WOAA 4H82A 5I4OA 1PWVA 2TCLA 4I35A 1QICA 1D8FA 2E2DA 3DWBA 1KUKA 3LQBA 3LMCA 4H3XA 4ON1A 3TVCA 3LQ0A 1SMPA 3LGPA 4A3WA 2CLTA 2OW1A 1UEAA 2DDFA 2SRTA 1MMPA 1I73A 3TSKA 5L7FA 2EROA 1B8YA 3KRYA 1Y8JA 3F16A 1G4KA 3N2VA 2I47A 2JNPA
chains in the Genus database with same CATH superfamily
1UTTA 4G9LA 3O2XA 1BQOA 3LIKA 2W12A 4H30A 3B2ZA 4WKEA 1ZTQA 3OHLA 4H49A 2DW2A 2QPJA 1CIZA 1PWUA 3DPEA 1O0TA 1QJJA 5JMYA 3EDZA 1KUHA 2ERPA 1GO8P 4QKZA 1XFXA 3KWVC 3DPFA 4DV8A 1Z3JA 5D2BA 4JIJA 2W0DA 1IAGA 4CTHA 4JQGA 3AYUA 5I2ZA 2A8HA 1D7XA 1FBLA 5BOYA 4FXQA 4L63A 2CKIA 1FLSA 4WK7A 1GKDA 1IABA 1PWWA 4HX3A 3AIGA 1SU3A 1ZVXA 1HOVA 4J4MA 3E8RA 1GO7P 1ROSA 1GXDA 2MLRA 2OI0A 5I12A 1O0QA 3WV2A 1OM8A 3KECA 4L7AA 2XS4A 1R55A 1ZXVA 1HTDA 2K9CA 2OVXA 1XURA 3Q2GA 3DSLA 1S4BP 2OY4A 4PKVA 4WKIA 1CGLA 1IADA 1JIWP 3DNGA 1BIWA 3DTKA 1XM5A 1BKCI 3VTGA 3ZVSA 1ASTA 1OO9A 3LUNA 3EWJA 3LKAA 4XM8A 1PWPA 2X3CA 1UTZA 5H8XA 1OM6A 1BKCE 4ZR5A 2YUFA 1ATLA 1JH1A 2DW0A 4A7BA 1KUIA 2FV5A 2KRJA 3BA0A 1R1JA 3K7LA 4I03A 5I3MA 2O3EA 3LUMA 2RJPA 1CGEA 3RTSA 2W13A 2YB9A 4H2EA 2PJTA 1EUBA 1IAEA 1CQRA 1YQYA 4FVLA 4WF6A 456CA 5D1SA 4AIGA 3EDGA 2AIGP 1MNCA 5I43A 3F17A 4JP4A 3L0VA 1G49A 5D1UA 3HBUP 5D1TA 3USNA 4GR8A 1JJ9A 2OW0A 4GWMA 4AYKA 3KEKA 2AYKA 1JAPA 2POJA 3HDAP 1DMTA 2E3XA 3TS4A 4XCTA 2OZRA 3ELMA 3L0TA 1RMZA 1QIAA 1XUDA 1Y93A 4ILWD 2MZEA 3I7GA 3G42A 3ZXHA 4L6TA 4WZVA 1QUAA 4GR3A 1JAOA 3GBOA 3EDIA 3P24A 1XFYA 1GE7A 4DF9A 5CZMA 1OM7A 4Q1LA 3LJTA 1OMJA 2XS3A 4AXQA 3DTIA 1IACA 1BKCA 1HFCA 5L79A 3ZUKA 4H84A 3CKIA 2MZIA 2J83A 2L0RA 4L19A 1MMQA 4JPAA 3V96B 3HY7A 4R3VA 3B92A 4PKUA 2WO8A 2DW1A 5CXAA 1SRPA 2O36A 3LILA 1USNA 1UMSA 1HY7A 2Y6DA 1XFVA 2WO9A 1HFSA 1R54A 1BUVM 1ZXCA 1JKYA 1JIZA 1AF0A 1QIBA 3KMEA 3HYGA 4FU4A 1OS9A 3LIRA 2D1NA 1YCMA 2W15A 4GWNA 4GR0A 5BOTA 1K7GA 5B5PA 1XFUA 4DPEA 4JA1A 1D5JA 4DD8A 2JIHA 4XBHA 2DDYA 3WV3A 2JT5A 2JSDA 3HBVP 3OHOA 1EAKA 2OY2A 4G0DA 2X3BA 3UVCA 5B5OA 2ERQA 2K2GA 3LJGA 1Y0VA 1JK3A 1CAQA 2V4BA 5LABA 3EHYA 1MMRA 2YIGA 3DTEA 1JAQA 3Q2HA 4HMAA 1C7KA 1XUCA 4IUWA 3VI1A 2FV9A 1Q3AA 1XFZA 1J7NA 1A86A 966CA 5D7WA 1OS2A 1B3DA 2JT6A 1BSWA 3DL1A 1YP1A 3I7IA 1AYKA 1BM6A 2N8RA 1KBCA 2X3AA 1SATA 3G5CA 3MA2A 5I0LA 1CXVA 3N2UA 1EB6A 4FXYP 1IAAA 3LK8A 1CK7A 3F19A 4EFSA 1CGFA 1PWQA 1WNIA 3B8ZA 2OXZA 1UMTA 2HU6A 3HDBA 1FM1A 2OW9A 1HV5A 4IN9A 1I76A 2W14A 1A85A 3O64A 1R1IA 1L6JA 1GE6A 1ZS0A 2OVZA 3SHIA 3LE9A 2USNA 3LEAA 2OW2A 3WV1A 3HY9A 4AUOA 1KUFA 4XM7A 1C3IA 3EHXA 3K7NA 5BPAA 1H71P 1BQQM 1K7IA 1KUGA 3F18A 4PKTA 1D8MA 1G12A 1G05A 1YOUA 4GF1A 3EDHA 1SLMA 4PKQA 3HB2P 3KEJA 5D3CA 1GE5A 4PKWA 1R1HA 1JANA 4PKSA 1ZP5A 1RM8A 1KAPP 3F15A 1TVIA 1C8TA 1BZSA 4GUYA 2OXWA 1QJIA 2RJQA 3RTTA 2J0TA 830CA 3AYKA 2X7MA 3U1RA 1DTHA 1OZ9A 4XM6A 3NX7A 4GQLA 2Z2DA 2OXUA 4H1QA 1BUDA 1G9KA 5CUHA 3TT4A 4H76A 1GKCA 1AKLA 1MMBA 3LJZA 2D1OA 4PKRA 1SLNA 1XAXA 3F1AA 3P1VA 1ND1A 2MLSA 1K7QA 2MZHA 2Y6CA 1XFWA 3KHIA 3KMCA 1I1IP 4IJOA 2WOAA 4H82A 5I4OA 1PWVA 2TCLA 4I35A 1QICA 1D8FA 2E2DA 3DWBA 1KUKA 3LQBA 3LMCA 4H3XA 4ON1A 3TVCA 3LQ0A 1SMPA 3LGPA 4A3WA 2CLTA 2OW1A 1UEAA 2DDFA 2SRTA 1MMPA 1I73A 3TSKA 5L7FA 2EROA 1B8YA 3KRYA 1Y8JA 3F16A 1G4KA 3N2VA 2I47A 2JNPA
chains in the Genus database with same CATH topology
1UTTA 4G9LA 3O2XA 1BQOA 3LIKA 2W12A 4H30A 3B2ZA 4WKEA 1ZTQA 3OHLA 4H49A 2DW2A 2QPJA 1CIZA 1PWUA 3DPEA 1O0TA 1QJJA 5JMYA 3EDZA 1KUHA 2ERPA 1GO8P 4QKZA 1XFXA 3KWVC 3DPFA 4DV8A 1Z3JA 5D2BA 4JIJA 2W0DA 1IAGA 4CTHA 4JQGA 3AYUA 5I2ZA 2A8HA 1D7XA 1FBLA 5BOYA 4FXQA 4L63A 2CKIA 1FLSA 4WK7A 1GKDA 1IABA 1PWWA 4HX3A 3AIGA 1SU3A 1ZVXA 1HOVA 4J4MA 3E8RA 1GO7P 1ROSA 1GXDA 2MLRA 2OI0A 5I12A 1O0QA 3WV2A 1OM8A 3KECA 4L7AA 2XS4A 1R55A 1ZXVA 1HTDA 2K9CA 2OVXA 1XURA 3Q2GA 3DSLA 1S4BP 2OY4A 4PKVA 4WKIA 1CGLA 1IADA 1JIWP 3DNGA 1BIWA 3DTKA 1BKCI 3VTGA 3ZVSA 1ASTA 1OO9A 3LUNA 3EWJA 3LKAA 4XM8A 1PWPA 2X3CA 1UTZA 5H8XA 1OM6A 1BKCE 4ZR5A 2YUFA 1ATLA 1JH1A 2DW0A 4A7BA 1KUIA 2FV5A 2KRJA 3BA0A 1R1JA 3K7LA 4I03A 5I3MA 2O3EA 3LUMA 2RJPA 1CGEA 3RTSA 2W13A 2YB9A 4H2EA 2PJTA 1EUBA 1IAEA 1CQRA 1YQYA 4FVLA 4WF6A 456CA 5D1SA 4AIGA 3EDGA 2AIGP 1MNCA 5I43A 3F17A 4JP4A 3L0VA 1G49A 5D1UA 3HBUP 5D1TA 3USNA 4GR8A 1JJ9A 2OW0A 4GWMA 4AYKA 3KEKA 2AYKA 1JAPA 2POJA 3HDAP 1DMTA 2E3XA 3TS4A 4XCTA 2OZRA 3ELMA 3L0TA 1RMZA 1QIAA 1XUDA 1Y93A 4ILWD 2MZEA 3I7GA 3G42A 3ZXHA 4L6TA 4WZVA 1QUAA 4GR3A 1JAOA 3GBOA 3EDIA 3P24A 1XFYA 1GE7A 4DF9A 5CZMA 1OM7A 4Q1LA 3LJTA 1OMJA 2XS3A 4AXQA 3DTIA 1IACA 1BKCA 1HFCA 5L79A 3ZUKA 4H84A 3CKIA 2MZIA 2J83A 2L0RA 4L19A 1MMQA 4JPAA 3V96B 3HY7A 4R3VA 3B92A 4PKUA 2WO8A 2DW1A 5CXAA 1SRPA 2O36A 3LILA 1USNA 1UMSA 1HY7A 2Y6DA 1XFVA 2WO9A 1HFSA 1R54A 1BUVM 1ZXCA 1JKYA 1JIZA 1AF0A 1QIBA 3KMEA 3HYGA 4FU4A 1OS9A 3LIRA 2D1NA 1YCMA 2W15A 4GWNA 4GR0A 5BOTA 1K7GA 5B5PA 1XFUA 4DPEA 4JA1A 1D5JA 4DD8A 2JIHA 4XBHA 2DDYA 3WV3A 2JT5A 2JSDA 3HBVP 3OHOA 1EAKA 2OY2A 4G0DA 2X3BA 3UVCA 5B5OA 2ERQA 2K2GA 3LJGA 1Y0VA 1JK3A 1CAQA 2V4BA 5LABA 3EHYA 1MMRA 2YIGA 3DTEA 1JAQA 3Q2HA 4HMAA 1C7KA 1XUCA 4IUWA 3VI1A 2FV9A 1Q3AA 1XFZA 1J7NA 1A86A 966CA 5D7WA 1OS2A 1B3DA 2JT6A 1BSWA 3DL1A 1YP1A 3I7IA 1AYKA 1BM6A 2N8RA 1KBCA 2X3AA 1SATA 3G5CA 3MA2A 5I0LA 1CXVA 3N2UA 1EB6A 4FXYP 1IAAA 3LK8A 1CK7A 3F19A 4EFSA 1CGFA 1PWQA 1WNIA 3B8ZA 2OXZA 1UMTA 2HU6A 3HDBA 1FM1A 2OW9A 1HV5A 4IN9A 1I76A 2W14A 1A85A 3O64A 1R1IA 1L6JA 1GE6A 1ZS0A 2OVZA 3SHIA 3LE9A 2USNA 3LEAA 2OW2A 3WV1A 3HY9A 4AUOA 1KUFA 4XM7A 1C3IA 3EHXA 3K7NA 5BPAA 1H71P 1BQQM 1K7IA 1KUGA 3F18A 4PKTA 1D8MA 1G12A 1G05A 1YOUA 4GF1A 3EDHA 1SLMA 4PKQA 3HB2P 3KEJA 5D3CA 1GE5A 4PKWA 1R1HA 1JANA 4PKSA 1ZP5A 1RM8A 1KAPP 3F15A 1C8TA 1BZSA 4GUYA 2OXWA 1QJIA 2RJQA 3RTTA 2J0TA 830CA 3AYKA 2X7MA 3U1RA 1DTHA 4XM6A 3NX7A 4GQLA 2Z2DA 2OXUA 4H1QA 1BUDA 1G9KA 5CUHA 3TT4A 4H76A 1GKCA 1AKLA 1MMBA 3LJZA 2D1OA 4PKRA 1SLNA 3F1AA 3P1VA 1ND1A 2MLSA 1K7QA 2MZHA 2Y6CA 1XFWA 3KHIA 3KMCA 1I1IP 4IJOA 2WOAA 4H82A 5I4OA 1PWVA 2TCLA 4I35A 1QICA 1D8FA 2E2DA 3DWBA 1KUKA 3LQBA 3LMCA 4H3XA 4ON1A 3TVCA 3LQ0A 1SMPA 3LGPA 4A3WA 2CLTA 2OW1A 1UEAA 2DDFA 2SRTA 1MMPA 1I73A 3TSKA 5L7FA 2EROA 1B8YA 3KRYA 1Y8JA 3F16A 1G4KA 3N2VA 2I47A 2JNPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UTT A;  4G9L A;  3O2X A;  1BQO A;  3LIK A;  2W12 A;  4H30 A;  3B2Z A;  4WKE A;  1ZTQ A;  3OHL A;  4H49 A;  2DW2 A;  2QPJ A;  1CIZ A;  1PWU A;  3DPE A;  1O0T A;  1QJJ A;  5JMY A;  3EDZ A;  1KUH A;  2ERP A;  1GO8 P;  4QKZ A;  1XFX A;  3KWV C;  3DPF A;  4DV8 A;  1Z3J A;  5D2B A;  4JIJ A;  2W0D A;  1IAG A;  4CTH A;  4JQG A;  3AYU A;  5I2Z A;  2A8H A;  1D7X A;  1FBL A;  5BOY A;  4FXQ A;  4L63 A;  2CKI A;  1FLS A;  4WK7 A;  1GKD A;  1IAB A;  1PWW A;  4HX3 A;  3AIG A;  1SU3 A;  1ZVX A;  1HOV A;  4J4M A;  3E8R A;  1GO7 P;  1ROS A;  1GXD A;  2MLR A;  2OI0 A;  5I12 A;  1O0Q A;  3WV2 A;  1OM8 A;  3KEC A;  2XS4 A;  1R55 A;  1ZXV A;  1HTD A;  2K9C A;  2OVX A;  1XUR A;  3Q2G A;  3DSL A;  1S4B P;  2OY4 A;  4PKV A;  4WKI A;  1CGL A;  1IAD A;  1JIW P;  3DNG A;  1BIW A;  1BKC I;  3VTG A;  3ZVS A;  1AST A;  1OO9 A;  3LUN A;  3EWJ A;  3LKA A;  4XM8 A;  1PWP A;  2X3C A;  1UTZ A;  5H8X A;  1OM6 A;  1BKC E;  4ZR5 A;  1ATL A;  1JH1 A;  2DW0 A;  4A7B A;  1KUI A;  2FV5 A;  2KRJ A;  3BA0 A;  1R1J A;  3K7L A;  4I03 A;  5I3M A;  2O3E A;  3LUM A;  2RJP A;  1CGE A;  3RTS A;  2W13 A;  2YB9 A;  4H2E A;  2PJT A;  1EUB A;  1IAE A;  1CQR A;  1YQY A;  4FVL A;  4WF6 A;  456C A;  5D1S A;  4AIG A;  3EDG A;  2AIG P;  1MNC A;  5I43 A;  3F17 A;  4JP4 A;  3L0V A;  1G49 A;  5D1U A;  3HBU P;  5D1T A;  3USN A;  4GR8 A;  1JJ9 A;  2OW0 A;  4GWM A;  4AYK A;  3KEK A;  2AYK A;  1JAP A;  2POJ A;  3HDA P;  1DMT A;  2E3X A;  3TS4 A;  4XCT A;  2OZR A;  3ELM A;  3L0T A;  1RMZ A;  1QIA A;  1XUD A;  1Y93 A;  4ILW D;  2MZE A;  3I7G A;  3G42 A;  3ZXH A;  4L6T A;  4WZV A;  1QUA A;  4GR3 A;  1JAO A;  3GBO A;  3EDI A;  3P24 A;  1XFY A;  1GE7 A;  4DF9 A;  5CZM A;  1OM7 A;  4Q1L A;  3LJT A;  1OMJ A;  2XS3 A;  4AXQ A;  1IAC A;  1BKC A;  1HFC A;  5L79 A;  3ZUK A;  4H84 A;  3CKI A;  2MZI A;  2J83 A;  2L0R A;  4L19 A;  1MMQ A;  4JPA A;  3V96 B;  3HY7 A;  4R3V A;  3B92 A;  4PKU A;  2WO8 A;  2DW1 A;  5CXA A;  1SRP A;  2O36 A;  3LIL A;  1USN A;  1UMS A;  1HY7 A;  2Y6D A;  1XFV A;  2WO9 A;  1HFS A;  1R54 A;  1BUV M;  1ZXC A;  1JKY A;  1JIZ A;  1AF0 A;  1QIB A;  3KME A;  3HYG A;  4FU4 A;  1OS9 A;  3LIR A;  2D1N A;  1YCM A;  2W15 A;  4GWN A;  4GR0 A;  5BOT A;  1K7G A;  5B5P A;  1XFU A;  4DPE A;  4JA1 A;  1D5J A;  4DD8 A;  2JIH A;  4XBH A;  2DDY A;  3WV3 A;  2JT5 A;  2JSD A;  3HBV P;  3OHO A;  1EAK A;  2OY2 A;  4G0D A;  2X3B A;  3UVC A;  5B5O A;  2ERQ A;  2K2G A;  3LJG A;  1Y0V A;  1JK3 A;  1CAQ A;  2V4B A;  5LAB A;  3EHY A;  1MMR A;  2YIG A;  1JAQ A;  3Q2H A;  4HMA A;  1C7K A;  1XUC A;  4IUW A;  3VI1 A;  2FV9 A;  1Q3A A;  1XFZ A;  1J7N A;  1A86 A;  966C A;  5D7W A;  1OS2 A;  1B3D A;  2JT6 A;  1BSW A;  3DL1 A;  1YP1 A;  3I7I A;  1AYK A;  1BM6 A;  2N8R A;  1KBC A;  2X3A A;  1SAT A;  3G5C A;  3MA2 A;  5I0L A;  1CXV A;  3N2U A;  1EB6 A;  4FXY P;  1IAA A;  3LK8 A;  1CK7 A;  3F19 A;  4EFS A;  1CGF A;  1PWQ A;  1WNI A;  3B8Z A;  2OXZ A;  1UMT A;  2HU6 A;  3HDB A;  1FM1 A;  2OW9 A;  1HV5 A;  4IN9 A;  1I76 A;  2W14 A;  1A85 A;  3O64 A;  1R1I A;  1L6J A;  1GE6 A;  1ZS0 A;  2OVZ A;  3SHI A;  3LE9 A;  2USN A;  3LEA A;  2OW2 A;  3WV1 A;  3HY9 A;  4AUO A;  1KUF A;  4XM7 A;  1C3I A;  3EHX A;  3K7N A;  5BPA A;  1H71 P;  1BQQ M;  1K7I A;  1KUG A;  3F18 A;  4PKT A;  1D8M A;  1G12 A;  1G05 A;  1YOU A;  4GF1 A;  3EDH A;  1SLM A;  4PKQ A;  3HB2 P;  3KEJ A;  5D3C A;  1GE5 A;  4PKW A;  1R1H A;  1JAN A;  4PKS A;  1ZP5 A;  1RM8 A;  1KAP P;  3F15 A;  1C8T A;  1BZS A;  4GUY A;  2OXW A;  1QJI A;  2RJQ A;  3RTT A;  2J0T A;  830C A;  3AYK A;  2X7M A;  3U1R A;  1DTH A;  4XM6 A;  3NX7 A;  4GQL A;  2Z2D A;  2OXU A;  4H1Q A;  1BUD A;  1G9K A;  5CUH A;  3TT4 A;  4H76 A;  1GKC A;  1AKL A;  1MMB A;  3LJZ A;  2D1O A;  4PKR A;  1SLN A;  3F1A A;  3P1V A;  1ND1 A;  2MLS A;  1K7Q A;  2MZH A;  2Y6C A;  1XFW A;  3KHI A;  3KMC A;  1I1I P;  4IJO A;  2WOA A;  4H82 A;  5I4O A;  1PWV A;  2TCL A;  4I35 A;  1QIC A;  1D8F A;  2E2D A;  3DWB A;  1KUK A;  3LQB A;  3LMC A;  4H3X A;  4ON1 A;  3TVC A;  3LQ0 A;  1SMP A;  3LGP A;  4A3W A;  2CLT A;  2OW1 A;  1UEA A;  2DDF A;  2SRT A;  1MMP A;  1I73 A;  3TSK A;  5L7F A;  2ERO A;  1B8Y A;  3KRY A;  1Y8J A;  3F16 A;  1G4K A;  3N2V A;  2I47 A;  2JNP A; 
#chains in the Genus database with same CATH topology
 1UTT A;  4G9L A;  3O2X A;  1BQO A;  3LIK A;  2W12 A;  4H30 A;  3B2Z A;  4WKE A;  1ZTQ A;  3OHL A;  4H49 A;  2DW2 A;  2QPJ A;  1CIZ A;  1PWU A;  3DPE A;  1O0T A;  1QJJ A;  5JMY A;  3EDZ A;  1KUH A;  2ERP A;  1GO8 P;  4QKZ A;  1XFX A;  3KWV C;  3DPF A;  4DV8 A;  1Z3J A;  5D2B A;  4JIJ A;  2W0D A;  1IAG A;  4CTH A;  4JQG A;  3AYU A;  5I2Z A;  2A8H A;  1D7X A;  1FBL A;  5BOY A;  4FXQ A;  4L63 A;  2CKI A;  1FLS A;  4WK7 A;  1GKD A;  1IAB A;  1PWW A;  4HX3 A;  3AIG A;  1SU3 A;  1ZVX A;  1HOV A;  4J4M A;  3E8R A;  1GO7 P;  1ROS A;  1GXD A;  2MLR A;  2OI0 A;  5I12 A;  1O0Q A;  3WV2 A;  1OM8 A;  3KEC A;  4L7A A;  2XS4 A;  1R55 A;  1ZXV A;  1HTD A;  2K9C A;  2OVX A;  1XUR A;  3Q2G A;  3DSL A;  1S4B P;  2OY4 A;  4PKV A;  4WKI A;  1CGL A;  1IAD A;  1JIW P;  3DNG A;  1BIW A;  3DTK A;  1XM5 A;  1BKC I;  3VTG A;  3ZVS A;  1AST A;  1OO9 A;  3LUN A;  3EWJ A;  3LKA A;  4XM8 A;  1PWP A;  2X3C A;  1UTZ A;  5H8X A;  1OM6 A;  1BKC E;  4ZR5 A;  2YUF A;  1ATL A;  1JH1 A;  2DW0 A;  4A7B A;  1KUI A;  2FV5 A;  2KRJ A;  3BA0 A;  1R1J A;  3K7L A;  4I03 A;  5I3M A;  2O3E A;  3LUM A;  2RJP A;  1CGE A;  3RTS A;  2W13 A;  2YB9 A;  4H2E A;  2PJT A;  1EUB A;  1IAE A;  1CQR A;  1YQY A;  4FVL A;  4WF6 A;  456C A;  5D1S A;  4AIG A;  3EDG A;  2AIG P;  1MNC A;  5I43 A;  3F17 A;  4JP4 A;  3L0V A;  1G49 A;  5D1U A;  3HBU P;  5D1T A;  3USN A;  4GR8 A;  1JJ9 A;  2OW0 A;  4GWM A;  4AYK A;  3KEK A;  2AYK A;  1JAP A;  2POJ A;  3HDA P;  1DMT A;  2E3X A;  3TS4 A;  4XCT A;  2OZR A;  3ELM A;  3L0T A;  1RMZ A;  1QIA A;  1XUD A;  1Y93 A;  4ILW D;  2MZE A;  3I7G A;  3G42 A;  3ZXH A;  4L6T A;  4WZV A;  1QUA A;  4GR3 A;  1JAO A;  3GBO A;  3EDI A;  3P24 A;  1XFY A;  1GE7 A;  4DF9 A;  5CZM A;  1OM7 A;  4Q1L A;  3LJT A;  1OMJ A;  2XS3 A;  4AXQ A;  3DTI A;  1IAC A;  1BKC A;  1HFC A;  5L79 A;  3ZUK A;  4H84 A;  3CKI A;  2MZI A;  2J83 A;  2L0R A;  4L19 A;  1MMQ A;  4JPA A;  3V96 B;  3HY7 A;  4R3V A;  3B92 A;  4PKU A;  2WO8 A;  2DW1 A;  5CXA A;  1SRP A;  2O36 A;  3LIL A;  1USN A;  1UMS A;  1HY7 A;  2Y6D A;  1XFV A;  2WO9 A;  1HFS A;  1R54 A;  1BUV M;  1ZXC A;  1JKY A;  1JIZ A;  1AF0 A;  1QIB A;  3KME A;  3HYG A;  4FU4 A;  1OS9 A;  3LIR A;  2D1N A;  1YCM A;  2W15 A;  4GWN A;  4GR0 A;  5BOT A;  1K7G A;  5B5P A;  1XFU A;  4DPE A;  4JA1 A;  1D5J A;  4DD8 A;  2JIH A;  4XBH A;  2DDY A;  3WV3 A;  2JT5 A;  2JSD A;  3HBV P;  3OHO A;  1EAK A;  2OY2 A;  4G0D A;  2X3B A;  3UVC A;  5B5O A;  2ERQ A;  2K2G A;  3LJG A;  1Y0V A;  1JK3 A;  1CAQ A;  2V4B A;  5LAB A;  3EHY A;  1MMR A;  2YIG A;  3DTE A;  1JAQ A;  3Q2H A;  4HMA A;  1C7K A;  1XUC A;  4IUW A;  3VI1 A;  2FV9 A;  1Q3A A;  1XFZ A;  1J7N A;  1A86 A;  966C A;  5D7W A;  1OS2 A;  1B3D A;  2JT6 A;  1BSW A;  3DL1 A;  1YP1 A;  3I7I A;  1AYK A;  1BM6 A;  2N8R A;  1KBC A;  2X3A A;  1SAT A;  3G5C A;  3MA2 A;  5I0L A;  1CXV A;  3N2U A;  1EB6 A;  4FXY P;  1IAA A;  3LK8 A;  1CK7 A;  3F19 A;  4EFS A;  1CGF A;  1PWQ A;  1WNI A;  3B8Z A;  2OXZ A;  1UMT A;  2HU6 A;  3HDB A;  1FM1 A;  2OW9 A;  1HV5 A;  4IN9 A;  1I76 A;  2W14 A;  1A85 A;  3O64 A;  1R1I A;  1L6J A;  1GE6 A;  1ZS0 A;  2OVZ A;  3SHI A;  3LE9 A;  2USN A;  3LEA A;  2OW2 A;  3WV1 A;  3HY9 A;  4AUO A;  1KUF A;  4XM7 A;  1C3I A;  3EHX A;  3K7N A;  5BPA A;  1H71 P;  1BQQ M;  1K7I A;  1KUG A;  3F18 A;  4PKT A;  1D8M A;  1G12 A;  1G05 A;  1YOU A;  4GF1 A;  3EDH A;  1SLM A;  4PKQ A;  3HB2 P;  3KEJ A;  5D3C A;  1GE5 A;  4PKW A;  1R1H A;  1JAN A;  4PKS A;  1ZP5 A;  1RM8 A;  1KAP P;  3F15 A;  1TVI A;  1C8T A;  1BZS A;  4GUY A;  2OXW A;  1QJI A;  2RJQ A;  3RTT A;  2J0T A;  830C A;  3AYK A;  2X7M A;  3U1R A;  1DTH A;  1OZ9 A;  4XM6 A;  3NX7 A;  4GQL A;  2Z2D A;  2OXU A;  4H1Q A;  1BUD A;  1G9K A;  5CUH A;  3TT4 A;  4H76 A;  1GKC A;  1AKL A;  1MMB A;  3LJZ A;  2D1O A;  4PKR A;  1SLN A;  1XAX A;  3F1A A;  3P1V A;  1ND1 A;  2MLS A;  1K7Q A;  2MZH A;  2Y6C A;  1XFW A;  3KHI A;  3KMC A;  1I1I P;  4IJO A;  2WOA A;  4H82 A;  5I4O A;  1PWV A;  2TCL A;  4I35 A;  1QIC A;  1D8F A;  2E2D A;  3DWB A;  1KUK A;  3LQB A;  3LMC A;  4H3X A;  4ON1 A;  3TVC A;  3LQ0 A;  1SMP A;  3LGP A;  4A3W A;  2CLT A;  2OW1 A;  1UEA A;  2DDF A;  2SRT A;  1MMP A;  1I73 A;  3TSK A;  5L7F A;  2ERO A;  1B8Y A;  3KRY A;  1Y8J A;  3F16 A;  1G4K A;  3N2V A;  2I47 A;  2JNP A; 
#chains in the Genus database with same CATH homology
 1UTT A;  4G9L A;  3O2X A;  1BQO A;  3LIK A;  2W12 A;  4H30 A;  3B2Z A;  4WKE A;  1ZTQ A;  3OHL A;  4H49 A;  2DW2 A;  2QPJ A;  1CIZ A;  1PWU A;  3DPE A;  1O0T A;  1QJJ A;  5JMY A;  3EDZ A;  1KUH A;  2ERP A;  1GO8 P;  4QKZ A;  1XFX A;  3KWV C;  3DPF A;  4DV8 A;  1Z3J A;  5D2B A;  4JIJ A;  2W0D A;  1IAG A;  4CTH A;  4JQG A;  3AYU A;  5I2Z A;  2A8H A;  1D7X A;  1FBL A;  5BOY A;  4FXQ A;  4L63 A;  2CKI A;  1FLS A;  4WK7 A;  1GKD A;  1IAB A;  1PWW A;  4HX3 A;  3AIG A;  1SU3 A;  1ZVX A;  1HOV A;  4J4M A;  3E8R A;  1GO7 P;  1ROS A;  1GXD A;  2MLR A;  2OI0 A;  5I12 A;  1O0Q A;  3WV2 A;  1OM8 A;  3KEC A;  4L7A A;  2XS4 A;  1R55 A;  1ZXV A;  1HTD A;  2K9C A;  2OVX A;  1XUR A;  3Q2G A;  3DSL A;  1S4B P;  2OY4 A;  4PKV A;  4WKI A;  1CGL A;  1IAD A;  1JIW P;  3DNG A;  1BIW A;  3DTK A;  1BKC I;  3VTG A;  3ZVS A;  1AST A;  1OO9 A;  3LUN A;  3EWJ A;  3LKA A;  4XM8 A;  1PWP A;  2X3C A;  1UTZ A;  5H8X A;  1OM6 A;  1BKC E;  4ZR5 A;  2YUF A;  1ATL A;  1JH1 A;  2DW0 A;  4A7B A;  1KUI A;  2FV5 A;  2KRJ A;  3BA0 A;  1R1J A;  3K7L A;  4I03 A;  5I3M A;  2O3E A;  3LUM A;  2RJP A;  1CGE A;  3RTS A;  2W13 A;  2YB9 A;  4H2E A;  2PJT A;  1EUB A;  1IAE A;  1CQR A;  1YQY A;  4FVL A;  4WF6 A;  456C A;  5D1S A;  4AIG A;  3EDG A;  2AIG P;  1MNC A;  5I43 A;  3F17 A;  4JP4 A;  3L0V A;  1G49 A;  5D1U A;  3HBU P;  5D1T A;  3USN A;  4GR8 A;  1JJ9 A;  2OW0 A;  4GWM A;  4AYK A;  3KEK A;  2AYK A;  1JAP A;  2POJ A;  3HDA P;  1DMT A;  2E3X A;  3TS4 A;  4XCT A;  2OZR A;  3ELM A;  3L0T A;  1RMZ A;  1QIA A;  1XUD A;  1Y93 A;  4ILW D;  2MZE A;  3I7G A;  3G42 A;  3ZXH A;  4L6T A;  4WZV A;  1QUA A;  4GR3 A;  1JAO A;  3GBO A;  3EDI A;  3P24 A;  1XFY A;  1GE7 A;  4DF9 A;  5CZM A;  1OM7 A;  4Q1L A;  3LJT A;  1OMJ A;  2XS3 A;  4AXQ A;  3DTI A;  1IAC A;  1BKC A;  1HFC A;  5L79 A;  3ZUK A;  4H84 A;  3CKI A;  2MZI A;  2J83 A;  2L0R A;  4L19 A;  1MMQ A;  4JPA A;  3V96 B;  3HY7 A;  4R3V A;  3B92 A;  4PKU A;  2WO8 A;  2DW1 A;  5CXA A;  1SRP A;  2O36 A;  3LIL A;  1USN A;  1UMS A;  1HY7 A;  2Y6D A;  1XFV A;  2WO9 A;  1HFS A;  1R54 A;  1BUV M;  1ZXC A;  1JKY A;  1JIZ A;  1AF0 A;  1QIB A;  3KME A;  3HYG A;  4FU4 A;  1OS9 A;  3LIR A;  2D1N A;  1YCM A;  2W15 A;  4GWN A;  4GR0 A;  5BOT A;  1K7G A;  5B5P A;  1XFU A;  4DPE A;  4JA1 A;  1D5J A;  4DD8 A;  2JIH A;  4XBH A;  2DDY A;  3WV3 A;  2JT5 A;  2JSD A;  3HBV P;  3OHO A;  1EAK A;  2OY2 A;  4G0D A;  2X3B A;  3UVC A;  5B5O A;  2ERQ A;  2K2G A;  3LJG A;  1Y0V A;  1JK3 A;  1CAQ A;  2V4B A;  5LAB A;  3EHY A;  1MMR A;  2YIG A;  3DTE A;  1JAQ A;  3Q2H A;  4HMA A;  1C7K A;  1XUC A;  4IUW A;  3VI1 A;  2FV9 A;  1Q3A A;  1XFZ A;  1J7N A;  1A86 A;  966C A;  5D7W A;  1OS2 A;  1B3D A;  2JT6 A;  1BSW A;  3DL1 A;  1YP1 A;  3I7I A;  1AYK A;  1BM6 A;  2N8R A;  1KBC A;  2X3A A;  1SAT A;  3G5C A;  3MA2 A;  5I0L A;  1CXV A;  3N2U A;  1EB6 A;  4FXY P;  1IAA A;  3LK8 A;  1CK7 A;  3F19 A;  4EFS A;  1CGF A;  1PWQ A;  1WNI A;  3B8Z A;  2OXZ A;  1UMT A;  2HU6 A;  3HDB A;  1FM1 A;  2OW9 A;  1HV5 A;  4IN9 A;  1I76 A;  2W14 A;  1A85 A;  3O64 A;  1R1I A;  1L6J A;  1GE6 A;  1ZS0 A;  2OVZ A;  3SHI A;  3LE9 A;  2USN A;  3LEA A;  2OW2 A;  3WV1 A;  3HY9 A;  4AUO A;  1KUF A;  4XM7 A;  1C3I A;  3EHX A;  3K7N A;  5BPA A;  1H71 P;  1BQQ M;  1K7I A;  1KUG A;  3F18 A;  4PKT A;  1D8M A;  1G12 A;  1G05 A;  1YOU A;  4GF1 A;  3EDH A;  1SLM A;  4PKQ A;  3HB2 P;  3KEJ A;  5D3C A;  1GE5 A;  4PKW A;  1R1H A;  1JAN A;  4PKS A;  1ZP5 A;  1RM8 A;  1KAP P;  3F15 A;  1C8T A;  1BZS A;  4GUY A;  2OXW A;  1QJI A;  2RJQ A;  3RTT A;  2J0T A;  830C A;  3AYK A;  2X7M A;  3U1R A;  1DTH A;  4XM6 A;  3NX7 A;  4GQL A;  2Z2D A;  2OXU A;  4H1Q A;  1BUD A;  1G9K A;  5CUH A;  3TT4 A;  4H76 A;  1GKC A;  1AKL A;  1MMB A;  3LJZ A;  2D1O A;  4PKR A;  1SLN A;  3F1A A;  3P1V A;  1ND1 A;  2MLS A;  1K7Q A;  2MZH A;  2Y6C A;  1XFW A;  3KHI A;  3KMC A;  1I1I P;  4IJO A;  2WOA A;  4H82 A;  5I4O A;  1PWV A;  2TCL A;  4I35 A;  1QIC A;  1D8F A;  2E2D A;  3DWB A;  1KUK A;  3LQB A;  3LMC A;  4H3X A;  4ON1 A;  3TVC A;  3LQ0 A;  1SMP A;  3LGP A;  4A3W A;  2CLT A;  2OW1 A;  1UEA A;  2DDF A;  2SRT A;  1MMP A;  1I73 A;  3TSK A;  5L7F A;  2ERO A;  1B8Y A;  3KRY A;  1Y8J A;  3F16 A;  1G4K A;  3N2V A;  2I47 A;  2JNP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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