5B5OA

Crystal structure of the catalytic domain of mmp-13 complexed with n-phenyl-4-((4h-1,2,4-triazol-3-ylsulfanyl)methyl)-1,3-thiazol-2-amine
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
170
structure length
167
Chain Sequence
YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGFMLPDDDVQGIQSLYGPGDEDP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of Novel, Highly Potent, and Selective Matrix Metalloproteinase (MMP)-13 Inhibitors with a 1,2,4-Triazol-3-yl Moiety as a Zinc Binding Group Using a Structure-Based Design Approach
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Collagenase 3
total genus 46
structure length 167
sequence length 170
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2016-05-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 5b5oA00
1YP1A 2RJPA 2OXZA 5L7FA 2JT6A 3LMCA 3ZUKA 2SRTA 3VTGA 2ERPA 1O0TA 1ZXVA 5CUHA 1MNCA 4Q1LA 1BQQM 1PWQA 1HFCA 3WV1A 4H1QA 1JAOA 5D3CA 5LABA 2OXWA 1ASTA 1IAAA 1HV5A 3AIGA 3F19A 1EUBA 1YOUA 1KUKA 3G5CA 3LEAA 3E8RA 3HBUP 3KRYA 4A3WA 4ZR5A 5I0LA 1GE5A 1L6JA 1CK7A 2AIGP 3OHOA 3B92A 4FXYP 5D2BA 2TCLA 3WV3A 3N2VA 2N8RA 3VI1A 3HY7A 2RJQA 4PKWA 4ILWD 456CA 2PJTA 3DPFA 2WOAA 2WO9A 1GO8P 1BQOA 1RM8A 1GE7A 1RMZA 1UMSA 1EB6A 3DWBA 4GWMA 4FXQA 4WKIA 1GO7P 3USNA 2XS3A 4XM7A 4XM6A 3KECA 3LILA 4PKVA 2DDFA 1OM8A 3EHYA 5D1UA 3DNGA 3DL1A 5JMYA 3EDHA 1ZXCA 2OXUA 1CGEA 4XCTA 1ROSA 3HDAP 3LE9A 1QUAA 3LJGA 1OM7A 2W0DA 4A7BA 3EDGA 1ZTQA 3O2XA 5L79A 1JH1A 2L0RA 4IN9A 4GUYA 1Q3AA 1K7QA 4GR8A 4PKSA 4H49A 3SHIA 2OVXA 2OVZA 1JKYA 1PWWA 1JIWP 4GWNA 1XFYA 3L0VA 1MMBA 1KUFA 3LK8A 1XFXA 2CLTA 1O0QA 1UEAA 1HTDA 2CKIA 2DW2A 2WO8A 2W13A 2W15A 2Y6DA 3N2UA 3BA0A 2OW2A 3DSLA 1BUDA 1C3IA 3F16A 4I03A 1B3DA 5BOYA 4PKRA 3P1VA 2OY2A 3LJTA 4H84A 1HFSA 1JIZA 3OHLA 1Z3JA 3HBVP 1QJIA 4H3XA 4JP4A 1A86A 1CXVA 1ZVXA 4HX3A 3LUNA 2O36A 2OW1A 2YB9A 3F1AA 4H30A 2K9CA 4G0DA 2OY4A 1OO9A 1YCMA 3F17A 1A85A 2J0TA 4ON1A 2ERQA 1CAQA 2FV5A 1C8TA 5I2ZA 1ATLA 1KAPP 1IAGA 3KMCA 3LIRA 4J4MA 1XFUA 1JJ9A 3RTSA 2JT5A 1JANA 1IADA 1KUHA 2W12A 5I12A 4GR0A 3HDBA 1KUGA 966CA 2KRJA 3ELMA 3KHIA 5B5PA 4GQLA 5D1SA 4GR3A 1BKCI 1SLMA 1I73A 2MZEA 3P24A 3HB2P 2JNPA 1SMPA 2EROA 5BOTA 1G12A 1BUVM 1AYKA 4QKZA 2A8HA 3F18A 1R1HA 3WV2A 1K7IA 3HYGA 5D7WA 1YQYA 4GF1A 3V96B 2AYKA 1BM6A 1G4KA 3HY9A 1AF0A 4WK7A 2XS4A 3I7IA 3TSKA 2DW0A 1BKCE 2W14A 4WZVA 1CQRA 3LIKA 3F15A 1GKCA 3AYKA 2QPJA 2Z2DA 1G49A 4FU4A 4EFSA 1G05A 5CZMA 2MZIA 4H76A 2DW1A 1HY7A 1PWVA 4AXQA 4PKTA 1XUCA 5D1TA 2X3AA 4WF6A 2V4BA 1D7XA 1FBLA 1CGLA 4I35A 1R1IA 2X3CA 2OZRA 4JIJA 1D5JA 3LQ0A 3LKAA 4JQGA 3NX7A 2X3BA 1C7KA 1MMPA 1OS9A 3L0TA 4PKQA 1GXDA 3LUMA 1CIZA 2X7MA 3DPEA 1FLSA 1Y8JA 1Y0VA 3K7LA 3LGPA 3CKIA 5CXAA 1H71P 3RTTA 2K2GA 1SRPA 1SATA 2OI0A 1S4BP 1OS2A 2MLSA 5BPAA 1WNIA 1PWUA 3G42A 2POJA 3KEJA 1UTTA 2E2DA 2YIGA 1BIWA 1XUDA 4JPAA 4XBHA 2OW0A 3TVCA 2JIHA 1XURA 1IAEA 1FM1A 4AIGA 1QICA 4HMAA 1GE6A 3TT4A 1OM6A 1R1JA 3EDZA 3U1RA 3KEKA 1BSWA 1UTZA 4IJOA 1D8FA 1I1IP 1BZSA 1JAPA 1IACA 1QIBA 3B2ZA 1MMQA 2J83A 1QIAA 3ZVSA 3AYUA 5I3MA 1JAQA 2MZHA 2D1NA 4DPEA 1ND1A 2E3XA 1SU3A 2O3EA 3KMEA 4AYKA 4PKUA 1KUIA 4L19A 1PWPA 1XFVA 1QJJA 3LJZA 3TS4A 2D1OA 3LQBA 3B8ZA 4R3VA 4XM8A 1B8YA 1R55A 4DD8A 5I4OA 1XFZA 2I47A 4DV8A 1XFWA 1G9KA 2HU6A 1HOVA 1ZP5A 1KBCA 4FVLA 2DDYA 1IABA 1K7GA 1ZS0A 4DF9A 1UMTA 5B5OA 2OW9A 4G9LA 1USNA 2MLRA 1JK3A 1D8MA 3MA2A 1AKLA 2Y6CA 830CA 3I7GA 4JA1A 1Y93A 3Q2GA 4IUWA 4L6TA 1J7NA 1I76A 3EDIA 1GKDA 4H2EA 4H82A 1BKCA 3UVCA 4WKEA 5I43A 3GBOA 4AUOA 4CTHA 2JSDA 1DTHA 1MMRA 5H8XA 1DMTA 1EAKA 1SLNA 4L63A 3EHXA 3EWJA 1OMJA 3ZXHA 3KWVC 3O64A 3K7NA 3Q2HA 1R54A 2FV9A 2USNA 1CGFA
chains in the Genus database with same CATH superfamily
1YP1A 2RJPA 2OXZA 5L7FA 2JT6A 3LMCA 3ZUKA 2SRTA 3VTGA 2ERPA 1O0TA 1ZXVA 5CUHA 1MNCA 4Q1LA 4L7AA 1BQQM 1PWQA 1HFCA 3WV1A 4H1QA 1JAOA 5D3CA 5LABA 2OXWA 1ASTA 1IAAA 1HV5A 3AIGA 3F19A 1EUBA 1YOUA 1KUKA 3G5CA 3LEAA 3E8RA 3HBUP 3KRYA 4A3WA 4ZR5A 5I0LA 1GE5A 1L6JA 1CK7A 2AIGP 3OHOA 3B92A 4FXYP 5D2BA 2TCLA 3WV3A 3N2VA 2N8RA 3VI1A 3HY7A 2RJQA 4PKWA 4ILWD 456CA 2PJTA 3DPFA 2WOAA 2WO9A 1GO8P 1BQOA 1RM8A 1GE7A 1RMZA 1UMSA 1EB6A 3DWBA 4GWMA 4FXQA 4WKIA 1GO7P 3USNA 2XS3A 4XM7A 4XM6A 3KECA 3LILA 4PKVA 2DDFA 1OM8A 3EHYA 5D1UA 3DNGA 3DL1A 5JMYA 3EDHA 1ZXCA 2OXUA 1CGEA 4XCTA 1ROSA 3HDAP 3LE9A 1QUAA 3LJGA 1OM7A 2W0DA 4A7BA 3EDGA 1ZTQA 3O2XA 5L79A 1JH1A 2L0RA 4IN9A 4GUYA 1Q3AA 1K7QA 4GR8A 4PKSA 4H49A 3SHIA 2OVXA 2OVZA 1JKYA 1PWWA 1JIWP 4GWNA 1XFYA 3L0VA 1MMBA 1KUFA 3LK8A 1XFXA 2CLTA 1XAXA 1O0QA 1UEAA 1HTDA 2CKIA 2DW2A 2WO8A 2W13A 2W15A 2Y6DA 3N2UA 3BA0A 2OW2A 3DSLA 1BUDA 1C3IA 3F16A 4I03A 1B3DA 5BOYA 4PKRA 3P1VA 2OY2A 3LJTA 4H84A 1HFSA 1JIZA 3OHLA 1Z3JA 3HBVP 1QJIA 4H3XA 4JP4A 1A86A 1CXVA 1ZVXA 4HX3A 3LUNA 2O36A 2OW1A 2YB9A 3F1AA 4H30A 2K9CA 4G0DA 2OY4A 1OO9A 1YCMA 3F17A 1A85A 2J0TA 4ON1A 2ERQA 1CAQA 2FV5A 1C8TA 5I2ZA 1ATLA 1KAPP 1IAGA 3KMCA 3LIRA 4J4MA 1XFUA 1JJ9A 3RTSA 2JT5A 1JANA 1IADA 1KUHA 2W12A 5I12A 4GR0A 3HDBA 1KUGA 966CA 2KRJA 3ELMA 3KHIA 5B5PA 4GQLA 5D1SA 4GR3A 1BKCI 1SLMA 1I73A 2MZEA 3P24A 3HB2P 2JNPA 1SMPA 2EROA 5BOTA 1G12A 1BUVM 1AYKA 4QKZA 2A8HA 3F18A 1R1HA 3WV2A 1K7IA 3HYGA 5D7WA 1OZ9A 1YQYA 4GF1A 3V96B 2AYKA 1BM6A 1G4KA 3HY9A 1AF0A 4WK7A 2XS4A 3I7IA 3TSKA 2DW0A 1BKCE 2W14A 4WZVA 1CQRA 3LIKA 3F15A 1GKCA 3AYKA 2QPJA 2Z2DA 1G49A 4FU4A 4EFSA 1G05A 5CZMA 2MZIA 4H76A 2DW1A 1HY7A 1PWVA 4AXQA 4PKTA 1XUCA 5D1TA 2X3AA 4WF6A 3DTEA 2V4BA 1D7XA 1FBLA 1CGLA 4I35A 1R1IA 2X3CA 2OZRA 4JIJA 1D5JA 3LQ0A 3LKAA 4JQGA 3NX7A 2X3BA 1C7KA 1MMPA 1OS9A 3L0TA 4PKQA 1GXDA 3LUMA 1CIZA 2X7MA 3DPEA 1FLSA 1Y8JA 1Y0VA 3K7LA 3LGPA 3CKIA 5CXAA 1H71P 3RTTA 2K2GA 1SRPA 1SATA 2OI0A 1S4BP 1OS2A 2MLSA 5BPAA 1WNIA 1PWUA 3G42A 2POJA 3KEJA 1UTTA 2E2DA 2YIGA 1BIWA 1XUDA 4JPAA 4XBHA 2OW0A 3TVCA 2JIHA 1XURA 1IAEA 1FM1A 4AIGA 1XM5A 1QICA 4HMAA 1GE6A 3TT4A 1OM6A 1R1JA 3EDZA 3U1RA 3KEKA 1BSWA 1UTZA 4IJOA 1D8FA 1I1IP 1BZSA 1JAPA 1IACA 1QIBA 3B2ZA 1MMQA 2J83A 1QIAA 3ZVSA 3AYUA 5I3MA 1JAQA 2MZHA 2D1NA 4DPEA 1ND1A 2E3XA 1SU3A 3DTIA 2O3EA 3KMEA 4AYKA 4PKUA 1KUIA 4L19A 1PWPA 1XFVA 1QJJA 3LJZA 3TS4A 2YUFA 2D1OA 3LQBA 3B8ZA 4R3VA 4XM8A 1B8YA 1R55A 4DD8A 5I4OA 1XFZA 2I47A 4DV8A 1XFWA 1G9KA 2HU6A 1HOVA 1ZP5A 1KBCA 4FVLA 2DDYA 1IABA 1K7GA 1ZS0A 4DF9A 1UMTA 5B5OA 2OW9A 4G9LA 1USNA 2MLRA 1JK3A 1D8MA 3MA2A 1AKLA 2Y6CA 3DTKA 830CA 3I7GA 4JA1A 1Y93A 3Q2GA 4IUWA 4L6TA 1J7NA 1I76A 3EDIA 1GKDA 4H2EA 4H82A 1BKCA 3UVCA 4WKEA 5I43A 1TVIA 3GBOA 4AUOA 4CTHA 2JSDA 1DTHA 1MMRA 5H8XA 1DMTA 1EAKA 1SLNA 4L63A 3EHXA 3EWJA 1OMJA 3ZXHA 3KWVC 3O64A 3K7NA 3Q2HA 1R54A 2FV9A 2USNA 1CGFA
chains in the Genus database with same CATH topology
1YP1A 2RJPA 2OXZA 5L7FA 2JT6A 3LMCA 3ZUKA 2SRTA 3VTGA 2ERPA 1O0TA 1ZXVA 5CUHA 1MNCA 4Q1LA 4L7AA 1BQQM 1PWQA 1HFCA 3WV1A 4H1QA 1JAOA 5D3CA 5LABA 2OXWA 1ASTA 1IAAA 1HV5A 3AIGA 3F19A 1EUBA 1YOUA 1KUKA 3G5CA 3LEAA 3E8RA 3HBUP 3KRYA 4A3WA 4ZR5A 5I0LA 1GE5A 1L6JA 1CK7A 2AIGP 3OHOA 3B92A 4FXYP 5D2BA 2TCLA 3WV3A 3N2VA 2N8RA 3VI1A 3HY7A 2RJQA 4PKWA 4ILWD 456CA 2PJTA 3DPFA 2WOAA 2WO9A 1GO8P 1BQOA 1RM8A 1GE7A 1RMZA 1UMSA 1EB6A 3DWBA 4GWMA 4FXQA 4WKIA 1GO7P 3USNA 2XS3A 4XM7A 4XM6A 3KECA 3LILA 4PKVA 2DDFA 1OM8A 3EHYA 5D1UA 3DNGA 3DL1A 5JMYA 3EDHA 1ZXCA 2OXUA 1CGEA 4XCTA 1ROSA 3HDAP 3LE9A 1QUAA 3LJGA 1OM7A 2W0DA 4A7BA 3EDGA 1ZTQA 3O2XA 5L79A 1JH1A 2L0RA 4IN9A 4GUYA 1Q3AA 1K7QA 4GR8A 4PKSA 4H49A 3SHIA 2OVXA 2OVZA 1JKYA 1PWWA 1JIWP 4GWNA 1XFYA 3L0VA 1MMBA 1KUFA 3LK8A 1XFXA 2CLTA 1O0QA 1UEAA 1HTDA 2CKIA 2DW2A 2WO8A 2W13A 2W15A 2Y6DA 3N2UA 3BA0A 2OW2A 3DSLA 1BUDA 1C3IA 3F16A 4I03A 1B3DA 5BOYA 4PKRA 3P1VA 2OY2A 3LJTA 4H84A 1HFSA 1JIZA 3OHLA 1Z3JA 3HBVP 1QJIA 4H3XA 4JP4A 1A86A 1CXVA 1ZVXA 4HX3A 3LUNA 2O36A 2OW1A 2YB9A 3F1AA 4H30A 2K9CA 4G0DA 2OY4A 1OO9A 1YCMA 3F17A 1A85A 2J0TA 4ON1A 2ERQA 1CAQA 2FV5A 1C8TA 5I2ZA 1ATLA 1KAPP 1IAGA 3KMCA 3LIRA 4J4MA 1XFUA 1JJ9A 3RTSA 2JT5A 1JANA 1IADA 1KUHA 2W12A 5I12A 4GR0A 3HDBA 1KUGA 966CA 2KRJA 3ELMA 3KHIA 5B5PA 4GQLA 5D1SA 4GR3A 1BKCI 1SLMA 1I73A 2MZEA 3P24A 3HB2P 2JNPA 1SMPA 2EROA 5BOTA 1G12A 1BUVM 1AYKA 4QKZA 2A8HA 3F18A 1R1HA 3WV2A 1K7IA 3HYGA 5D7WA 1YQYA 4GF1A 3V96B 2AYKA 1BM6A 1G4KA 3HY9A 1AF0A 4WK7A 2XS4A 3I7IA 3TSKA 2DW0A 1BKCE 2W14A 4WZVA 1CQRA 3LIKA 3F15A 1GKCA 3AYKA 2QPJA 2Z2DA 1G49A 4FU4A 4EFSA 1G05A 5CZMA 2MZIA 4H76A 2DW1A 1HY7A 1PWVA 4AXQA 4PKTA 1XUCA 5D1TA 2X3AA 4WF6A 3DTEA 2V4BA 1D7XA 1FBLA 1CGLA 4I35A 1R1IA 2X3CA 2OZRA 4JIJA 1D5JA 3LQ0A 3LKAA 4JQGA 3NX7A 2X3BA 1C7KA 1MMPA 1OS9A 3L0TA 4PKQA 1GXDA 3LUMA 1CIZA 2X7MA 3DPEA 1FLSA 1Y8JA 1Y0VA 3K7LA 3LGPA 3CKIA 5CXAA 1H71P 3RTTA 2K2GA 1SRPA 1SATA 2OI0A 1S4BP 1OS2A 2MLSA 5BPAA 1WNIA 1PWUA 3G42A 2POJA 3KEJA 1UTTA 2E2DA 2YIGA 1BIWA 1XUDA 4JPAA 4XBHA 2OW0A 3TVCA 2JIHA 1XURA 1IAEA 1FM1A 4AIGA 1QICA 4HMAA 1GE6A 3TT4A 1OM6A 1R1JA 3EDZA 3U1RA 3KEKA 1BSWA 1UTZA 4IJOA 1D8FA 1I1IP 1BZSA 1JAPA 1IACA 1QIBA 3B2ZA 1MMQA 2J83A 1QIAA 3ZVSA 3AYUA 5I3MA 1JAQA 2MZHA 2D1NA 4DPEA 1ND1A 2E3XA 1SU3A 3DTIA 2O3EA 3KMEA 4AYKA 4PKUA 1KUIA 4L19A 1PWPA 1XFVA 1QJJA 3LJZA 3TS4A 2YUFA 2D1OA 3LQBA 3B8ZA 4R3VA 4XM8A 1B8YA 1R55A 4DD8A 5I4OA 1XFZA 2I47A 4DV8A 1XFWA 1G9KA 2HU6A 1HOVA 1ZP5A 1KBCA 4FVLA 2DDYA 1IABA 1K7GA 1ZS0A 4DF9A 1UMTA 5B5OA 2OW9A 4G9LA 1USNA 2MLRA 1JK3A 1D8MA 3MA2A 1AKLA 2Y6CA 3DTKA 830CA 3I7GA 4JA1A 1Y93A 3Q2GA 4IUWA 4L6TA 1J7NA 1I76A 3EDIA 1GKDA 4H2EA 4H82A 1BKCA 3UVCA 4WKEA 5I43A 3GBOA 4AUOA 4CTHA 2JSDA 1DTHA 1MMRA 5H8XA 1DMTA 1EAKA 1SLNA 4L63A 3EHXA 3EWJA 1OMJA 3ZXHA 3KWVC 3O64A 3K7NA 3Q2HA 1R54A 2FV9A 2USNA 1CGFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YP1 A;  2RJP A;  2OXZ A;  5L7F A;  2JT6 A;  3LMC A;  3ZUK A;  2SRT A;  3VTG A;  2ERP A;  1O0T A;  1ZXV A;  5CUH A;  1MNC A;  4Q1L A;  1BQQ M;  1PWQ A;  1HFC A;  3WV1 A;  4H1Q A;  1JAO A;  5D3C A;  5LAB A;  2OXW A;  1AST A;  1IAA A;  1HV5 A;  3AIG A;  3F19 A;  1EUB A;  1YOU A;  1KUK A;  3G5C A;  3LEA A;  3E8R A;  3HBU P;  3KRY A;  4A3W A;  4ZR5 A;  5I0L A;  1GE5 A;  1L6J A;  1CK7 A;  2AIG P;  3OHO A;  3B92 A;  4FXY P;  5D2B A;  2TCL A;  3WV3 A;  3N2V A;  2N8R A;  3VI1 A;  3HY7 A;  2RJQ A;  4PKW A;  4ILW D;  456C A;  2PJT A;  3DPF A;  2WOA A;  2WO9 A;  1GO8 P;  1BQO A;  1RM8 A;  1GE7 A;  1RMZ A;  1UMS A;  1EB6 A;  3DWB A;  4GWM A;  4FXQ A;  4WKI A;  1GO7 P;  3USN A;  2XS3 A;  4XM7 A;  4XM6 A;  3KEC A;  3LIL A;  4PKV A;  2DDF A;  1OM8 A;  3EHY A;  5D1U A;  3DNG A;  3DL1 A;  5JMY A;  3EDH A;  1ZXC A;  2OXU A;  1CGE A;  4XCT A;  1ROS A;  3HDA P;  3LE9 A;  1QUA A;  3LJG A;  1OM7 A;  2W0D A;  4A7B A;  3EDG A;  1ZTQ A;  3O2X A;  5L79 A;  1JH1 A;  2L0R A;  4IN9 A;  4GUY A;  1Q3A A;  1K7Q A;  4GR8 A;  4PKS A;  4H49 A;  3SHI A;  2OVX A;  2OVZ A;  1JKY A;  1PWW A;  1JIW P;  4GWN A;  1XFY A;  3L0V A;  1MMB A;  1KUF A;  3LK8 A;  1XFX A;  2CLT A;  1O0Q A;  1UEA A;  1HTD A;  2CKI A;  2DW2 A;  2WO8 A;  2W13 A;  2W15 A;  2Y6D A;  3N2U A;  3BA0 A;  2OW2 A;  3DSL A;  1BUD A;  1C3I A;  3F16 A;  4I03 A;  1B3D A;  5BOY A;  4PKR A;  3P1V A;  2OY2 A;  3LJT A;  4H84 A;  1HFS A;  1JIZ A;  3OHL A;  1Z3J A;  3HBV P;  1QJI A;  4H3X A;  4JP4 A;  1A86 A;  1CXV A;  1ZVX A;  4HX3 A;  3LUN A;  2O36 A;  2OW1 A;  2YB9 A;  3F1A A;  4H30 A;  2K9C A;  4G0D A;  2OY4 A;  1OO9 A;  1YCM A;  3F17 A;  1A85 A;  2J0T A;  4ON1 A;  2ERQ A;  1CAQ A;  2FV5 A;  1C8T A;  5I2Z A;  1ATL A;  1KAP P;  1IAG A;  3KMC A;  3LIR A;  4J4M A;  1XFU A;  1JJ9 A;  3RTS A;  2JT5 A;  1JAN A;  1IAD A;  1KUH A;  2W12 A;  5I12 A;  4GR0 A;  3HDB A;  1KUG A;  966C A;  2KRJ A;  3ELM A;  3KHI A;  5B5P A;  4GQL A;  5D1S A;  4GR3 A;  1BKC I;  1SLM A;  1I73 A;  2MZE A;  3P24 A;  3HB2 P;  2JNP A;  1SMP A;  2ERO A;  5BOT A;  1G12 A;  1BUV M;  1AYK A;  4QKZ A;  2A8H A;  3F18 A;  1R1H A;  3WV2 A;  1K7I A;  3HYG A;  5D7W A;  1YQY A;  4GF1 A;  3V96 B;  2AYK A;  1BM6 A;  1G4K A;  3HY9 A;  1AF0 A;  4WK7 A;  2XS4 A;  3I7I A;  3TSK A;  2DW0 A;  1BKC E;  2W14 A;  4WZV A;  1CQR A;  3LIK A;  3F15 A;  1GKC A;  3AYK A;  2QPJ A;  2Z2D A;  1G49 A;  4FU4 A;  4EFS A;  1G05 A;  5CZM A;  2MZI A;  4H76 A;  2DW1 A;  1HY7 A;  1PWV A;  4AXQ A;  4PKT A;  1XUC A;  5D1T A;  2X3A A;  4WF6 A;  2V4B A;  1D7X A;  1FBL A;  1CGL A;  4I35 A;  1R1I A;  2X3C A;  2OZR A;  4JIJ A;  1D5J A;  3LQ0 A;  3LKA A;  4JQG A;  3NX7 A;  2X3B A;  1C7K A;  1MMP A;  1OS9 A;  3L0T A;  4PKQ A;  1GXD A;  3LUM A;  1CIZ A;  2X7M A;  3DPE A;  1FLS A;  1Y8J A;  1Y0V A;  3K7L A;  3LGP A;  3CKI A;  5CXA A;  1H71 P;  3RTT A;  2K2G A;  1SRP A;  1SAT A;  2OI0 A;  1S4B P;  1OS2 A;  2MLS A;  5BPA A;  1WNI A;  1PWU A;  3G42 A;  2POJ A;  3KEJ A;  1UTT A;  2E2D A;  2YIG A;  1BIW A;  1XUD A;  4JPA A;  4XBH A;  2OW0 A;  3TVC A;  2JIH A;  1XUR A;  1IAE A;  1FM1 A;  4AIG A;  1QIC A;  4HMA A;  1GE6 A;  3TT4 A;  1OM6 A;  1R1J A;  3EDZ A;  3U1R A;  3KEK A;  1BSW A;  1UTZ A;  4IJO A;  1D8F A;  1I1I P;  1BZS A;  1JAP A;  1IAC A;  1QIB A;  3B2Z A;  1MMQ A;  2J83 A;  1QIA A;  3ZVS A;  3AYU A;  5I3M A;  1JAQ A;  2MZH A;  2D1N A;  4DPE A;  1ND1 A;  2E3X A;  1SU3 A;  2O3E A;  3KME A;  4AYK A;  4PKU A;  1KUI A;  4L19 A;  1PWP A;  1XFV A;  1QJJ A;  3LJZ A;  3TS4 A;  2D1O A;  3LQB A;  3B8Z A;  4R3V A;  4XM8 A;  1B8Y A;  1R55 A;  4DD8 A;  5I4O A;  1XFZ A;  2I47 A;  4DV8 A;  1XFW A;  1G9K A;  2HU6 A;  1HOV A;  1ZP5 A;  1KBC A;  4FVL A;  2DDY A;  1IAB A;  1K7G A;  1ZS0 A;  4DF9 A;  1UMT A;  5B5O A;  2OW9 A;  4G9L A;  1USN A;  2MLR A;  1JK3 A;  1D8M A;  3MA2 A;  1AKL A;  2Y6C A;  830C A;  3I7G A;  4JA1 A;  1Y93 A;  3Q2G A;  4IUW A;  4L6T A;  1J7N A;  1I76 A;  3EDI A;  1GKD A;  4H2E A;  4H82 A;  1BKC A;  3UVC A;  4WKE A;  5I43 A;  3GBO A;  4AUO A;  4CTH A;  2JSD A;  1DTH A;  1MMR A;  5H8X A;  1DMT A;  1EAK A;  1SLN A;  4L63 A;  3EHX A;  3EWJ A;  1OMJ A;  3ZXH A;  3KWV C;  3O64 A;  3K7N A;  3Q2H A;  1R54 A;  2FV9 A;  2USN A;  1CGF A; 
#chains in the Genus database with same CATH topology
 1YP1 A;  2RJP A;  2OXZ A;  5L7F A;  2JT6 A;  3LMC A;  3ZUK A;  2SRT A;  3VTG A;  2ERP A;  1O0T A;  1ZXV A;  5CUH A;  1MNC A;  4Q1L A;  4L7A A;  1BQQ M;  1PWQ A;  1HFC A;  3WV1 A;  4H1Q A;  1JAO A;  5D3C A;  5LAB A;  2OXW A;  1AST A;  1IAA A;  1HV5 A;  3AIG A;  3F19 A;  1EUB A;  1YOU A;  1KUK A;  3G5C A;  3LEA A;  3E8R A;  3HBU P;  3KRY A;  4A3W A;  4ZR5 A;  5I0L A;  1GE5 A;  1L6J A;  1CK7 A;  2AIG P;  3OHO A;  3B92 A;  4FXY P;  5D2B A;  2TCL A;  3WV3 A;  3N2V A;  2N8R A;  3VI1 A;  3HY7 A;  2RJQ A;  4PKW A;  4ILW D;  456C A;  2PJT A;  3DPF A;  2WOA A;  2WO9 A;  1GO8 P;  1BQO A;  1RM8 A;  1GE7 A;  1RMZ A;  1UMS A;  1EB6 A;  3DWB A;  4GWM A;  4FXQ A;  4WKI A;  1GO7 P;  3USN A;  2XS3 A;  4XM7 A;  4XM6 A;  3KEC A;  3LIL A;  4PKV A;  2DDF A;  1OM8 A;  3EHY A;  5D1U A;  3DNG A;  3DL1 A;  5JMY A;  3EDH A;  1ZXC A;  2OXU A;  1CGE A;  4XCT A;  1ROS A;  3HDA P;  3LE9 A;  1QUA A;  3LJG A;  1OM7 A;  2W0D A;  4A7B A;  3EDG A;  1ZTQ A;  3O2X A;  5L79 A;  1JH1 A;  2L0R A;  4IN9 A;  4GUY A;  1Q3A A;  1K7Q A;  4GR8 A;  4PKS A;  4H49 A;  3SHI A;  2OVX A;  2OVZ A;  1JKY A;  1PWW A;  1JIW P;  4GWN A;  1XFY A;  3L0V A;  1MMB A;  1KUF A;  3LK8 A;  1XFX A;  2CLT A;  1XAX A;  1O0Q A;  1UEA A;  1HTD A;  2CKI A;  2DW2 A;  2WO8 A;  2W13 A;  2W15 A;  2Y6D A;  3N2U A;  3BA0 A;  2OW2 A;  3DSL A;  1BUD A;  1C3I A;  3F16 A;  4I03 A;  1B3D A;  5BOY A;  4PKR A;  3P1V A;  2OY2 A;  3LJT A;  4H84 A;  1HFS A;  1JIZ A;  3OHL A;  1Z3J A;  3HBV P;  1QJI A;  4H3X A;  4JP4 A;  1A86 A;  1CXV A;  1ZVX A;  4HX3 A;  3LUN A;  2O36 A;  2OW1 A;  2YB9 A;  3F1A A;  4H30 A;  2K9C A;  4G0D A;  2OY4 A;  1OO9 A;  1YCM A;  3F17 A;  1A85 A;  2J0T A;  4ON1 A;  2ERQ A;  1CAQ A;  2FV5 A;  1C8T A;  5I2Z A;  1ATL A;  1KAP P;  1IAG A;  3KMC A;  3LIR A;  4J4M A;  1XFU A;  1JJ9 A;  3RTS A;  2JT5 A;  1JAN A;  1IAD A;  1KUH A;  2W12 A;  5I12 A;  4GR0 A;  3HDB A;  1KUG A;  966C A;  2KRJ A;  3ELM A;  3KHI A;  5B5P A;  4GQL A;  5D1S A;  4GR3 A;  1BKC I;  1SLM A;  1I73 A;  2MZE A;  3P24 A;  3HB2 P;  2JNP A;  1SMP A;  2ERO A;  5BOT A;  1G12 A;  1BUV M;  1AYK A;  4QKZ A;  2A8H A;  3F18 A;  1R1H A;  3WV2 A;  1K7I A;  3HYG A;  5D7W A;  1OZ9 A;  1YQY A;  4GF1 A;  3V96 B;  2AYK A;  1BM6 A;  1G4K A;  3HY9 A;  1AF0 A;  4WK7 A;  2XS4 A;  3I7I A;  3TSK A;  2DW0 A;  1BKC E;  2W14 A;  4WZV A;  1CQR A;  3LIK A;  3F15 A;  1GKC A;  3AYK A;  2QPJ A;  2Z2D A;  1G49 A;  4FU4 A;  4EFS A;  1G05 A;  5CZM A;  2MZI A;  4H76 A;  2DW1 A;  1HY7 A;  1PWV A;  4AXQ A;  4PKT A;  1XUC A;  5D1T A;  2X3A A;  4WF6 A;  3DTE A;  2V4B A;  1D7X A;  1FBL A;  1CGL A;  4I35 A;  1R1I A;  2X3C A;  2OZR A;  4JIJ A;  1D5J A;  3LQ0 A;  3LKA A;  4JQG A;  3NX7 A;  2X3B A;  1C7K A;  1MMP A;  1OS9 A;  3L0T A;  4PKQ A;  1GXD A;  3LUM A;  1CIZ A;  2X7M A;  3DPE A;  1FLS A;  1Y8J A;  1Y0V A;  3K7L A;  3LGP A;  3CKI A;  5CXA A;  1H71 P;  3RTT A;  2K2G A;  1SRP A;  1SAT A;  2OI0 A;  1S4B P;  1OS2 A;  2MLS A;  5BPA A;  1WNI A;  1PWU A;  3G42 A;  2POJ A;  3KEJ A;  1UTT A;  2E2D A;  2YIG A;  1BIW A;  1XUD A;  4JPA A;  4XBH A;  2OW0 A;  3TVC A;  2JIH A;  1XUR A;  1IAE A;  1FM1 A;  4AIG A;  1XM5 A;  1QIC A;  4HMA A;  1GE6 A;  3TT4 A;  1OM6 A;  1R1J A;  3EDZ A;  3U1R A;  3KEK A;  1BSW A;  1UTZ A;  4IJO A;  1D8F A;  1I1I P;  1BZS A;  1JAP A;  1IAC A;  1QIB A;  3B2Z A;  1MMQ A;  2J83 A;  1QIA A;  3ZVS A;  3AYU A;  5I3M A;  1JAQ A;  2MZH A;  2D1N A;  4DPE A;  1ND1 A;  2E3X A;  1SU3 A;  3DTI A;  2O3E A;  3KME A;  4AYK A;  4PKU A;  1KUI A;  4L19 A;  1PWP A;  1XFV A;  1QJJ A;  3LJZ A;  3TS4 A;  2YUF A;  2D1O A;  3LQB A;  3B8Z A;  4R3V A;  4XM8 A;  1B8Y A;  1R55 A;  4DD8 A;  5I4O A;  1XFZ A;  2I47 A;  4DV8 A;  1XFW A;  1G9K A;  2HU6 A;  1HOV A;  1ZP5 A;  1KBC A;  4FVL A;  2DDY A;  1IAB A;  1K7G A;  1ZS0 A;  4DF9 A;  1UMT A;  5B5O A;  2OW9 A;  4G9L A;  1USN A;  2MLR A;  1JK3 A;  1D8M A;  3MA2 A;  1AKL A;  2Y6C A;  3DTK A;  830C A;  3I7G A;  4JA1 A;  1Y93 A;  3Q2G A;  4IUW A;  4L6T A;  1J7N A;  1I76 A;  3EDI A;  1GKD A;  4H2E A;  4H82 A;  1BKC A;  3UVC A;  4WKE A;  5I43 A;  1TVI A;  3GBO A;  4AUO A;  4CTH A;  2JSD A;  1DTH A;  1MMR A;  5H8X A;  1DMT A;  1EAK A;  1SLN A;  4L63 A;  3EHX A;  3EWJ A;  1OMJ A;  3ZXH A;  3KWV C;  3O64 A;  3K7N A;  3Q2H A;  1R54 A;  2FV9 A;  2USN A;  1CGF A; 
#chains in the Genus database with same CATH homology
 1YP1 A;  2RJP A;  2OXZ A;  5L7F A;  2JT6 A;  3LMC A;  3ZUK A;  2SRT A;  3VTG A;  2ERP A;  1O0T A;  1ZXV A;  5CUH A;  1MNC A;  4Q1L A;  4L7A A;  1BQQ M;  1PWQ A;  1HFC A;  3WV1 A;  4H1Q A;  1JAO A;  5D3C A;  5LAB A;  2OXW A;  1AST A;  1IAA A;  1HV5 A;  3AIG A;  3F19 A;  1EUB A;  1YOU A;  1KUK A;  3G5C A;  3LEA A;  3E8R A;  3HBU P;  3KRY A;  4A3W A;  4ZR5 A;  5I0L A;  1GE5 A;  1L6J A;  1CK7 A;  2AIG P;  3OHO A;  3B92 A;  4FXY P;  5D2B A;  2TCL A;  3WV3 A;  3N2V A;  2N8R A;  3VI1 A;  3HY7 A;  2RJQ A;  4PKW A;  4ILW D;  456C A;  2PJT A;  3DPF A;  2WOA A;  2WO9 A;  1GO8 P;  1BQO A;  1RM8 A;  1GE7 A;  1RMZ A;  1UMS A;  1EB6 A;  3DWB A;  4GWM A;  4FXQ A;  4WKI A;  1GO7 P;  3USN A;  2XS3 A;  4XM7 A;  4XM6 A;  3KEC A;  3LIL A;  4PKV A;  2DDF A;  1OM8 A;  3EHY A;  5D1U A;  3DNG A;  3DL1 A;  5JMY A;  3EDH A;  1ZXC A;  2OXU A;  1CGE A;  4XCT A;  1ROS A;  3HDA P;  3LE9 A;  1QUA A;  3LJG A;  1OM7 A;  2W0D A;  4A7B A;  3EDG A;  1ZTQ A;  3O2X A;  5L79 A;  1JH1 A;  2L0R A;  4IN9 A;  4GUY A;  1Q3A A;  1K7Q A;  4GR8 A;  4PKS A;  4H49 A;  3SHI A;  2OVX A;  2OVZ A;  1JKY A;  1PWW A;  1JIW P;  4GWN A;  1XFY A;  3L0V A;  1MMB A;  1KUF A;  3LK8 A;  1XFX A;  2CLT A;  1O0Q A;  1UEA A;  1HTD A;  2CKI A;  2DW2 A;  2WO8 A;  2W13 A;  2W15 A;  2Y6D A;  3N2U A;  3BA0 A;  2OW2 A;  3DSL A;  1BUD A;  1C3I A;  3F16 A;  4I03 A;  1B3D A;  5BOY A;  4PKR A;  3P1V A;  2OY2 A;  3LJT A;  4H84 A;  1HFS A;  1JIZ A;  3OHL A;  1Z3J A;  3HBV P;  1QJI A;  4H3X A;  4JP4 A;  1A86 A;  1CXV A;  1ZVX A;  4HX3 A;  3LUN A;  2O36 A;  2OW1 A;  2YB9 A;  3F1A A;  4H30 A;  2K9C A;  4G0D A;  2OY4 A;  1OO9 A;  1YCM A;  3F17 A;  1A85 A;  2J0T A;  4ON1 A;  2ERQ A;  1CAQ A;  2FV5 A;  1C8T A;  5I2Z A;  1ATL A;  1KAP P;  1IAG A;  3KMC A;  3LIR A;  4J4M A;  1XFU A;  1JJ9 A;  3RTS A;  2JT5 A;  1JAN A;  1IAD A;  1KUH A;  2W12 A;  5I12 A;  4GR0 A;  3HDB A;  1KUG A;  966C A;  2KRJ A;  3ELM A;  3KHI A;  5B5P A;  4GQL A;  5D1S A;  4GR3 A;  1BKC I;  1SLM A;  1I73 A;  2MZE A;  3P24 A;  3HB2 P;  2JNP A;  1SMP A;  2ERO A;  5BOT A;  1G12 A;  1BUV M;  1AYK A;  4QKZ A;  2A8H A;  3F18 A;  1R1H A;  3WV2 A;  1K7I A;  3HYG A;  5D7W A;  1YQY A;  4GF1 A;  3V96 B;  2AYK A;  1BM6 A;  1G4K A;  3HY9 A;  1AF0 A;  4WK7 A;  2XS4 A;  3I7I A;  3TSK A;  2DW0 A;  1BKC E;  2W14 A;  4WZV A;  1CQR A;  3LIK A;  3F15 A;  1GKC A;  3AYK A;  2QPJ A;  2Z2D A;  1G49 A;  4FU4 A;  4EFS A;  1G05 A;  5CZM A;  2MZI A;  4H76 A;  2DW1 A;  1HY7 A;  1PWV A;  4AXQ A;  4PKT A;  1XUC A;  5D1T A;  2X3A A;  4WF6 A;  3DTE A;  2V4B A;  1D7X A;  1FBL A;  1CGL A;  4I35 A;  1R1I A;  2X3C A;  2OZR A;  4JIJ A;  1D5J A;  3LQ0 A;  3LKA A;  4JQG A;  3NX7 A;  2X3B A;  1C7K A;  1MMP A;  1OS9 A;  3L0T A;  4PKQ A;  1GXD A;  3LUM A;  1CIZ A;  2X7M A;  3DPE A;  1FLS A;  1Y8J A;  1Y0V A;  3K7L A;  3LGP A;  3CKI A;  5CXA A;  1H71 P;  3RTT A;  2K2G A;  1SRP A;  1SAT A;  2OI0 A;  1S4B P;  1OS2 A;  2MLS A;  5BPA A;  1WNI A;  1PWU A;  3G42 A;  2POJ A;  3KEJ A;  1UTT A;  2E2D A;  2YIG A;  1BIW A;  1XUD A;  4JPA A;  4XBH A;  2OW0 A;  3TVC A;  2JIH A;  1XUR A;  1IAE A;  1FM1 A;  4AIG A;  1QIC A;  4HMA A;  1GE6 A;  3TT4 A;  1OM6 A;  1R1J A;  3EDZ A;  3U1R A;  3KEK A;  1BSW A;  1UTZ A;  4IJO A;  1D8F A;  1I1I P;  1BZS A;  1JAP A;  1IAC A;  1QIB A;  3B2Z A;  1MMQ A;  2J83 A;  1QIA A;  3ZVS A;  3AYU A;  5I3M A;  1JAQ A;  2MZH A;  2D1N A;  4DPE A;  1ND1 A;  2E3X A;  1SU3 A;  3DTI A;  2O3E A;  3KME A;  4AYK A;  4PKU A;  1KUI A;  4L19 A;  1PWP A;  1XFV A;  1QJJ A;  3LJZ A;  3TS4 A;  2YUF A;  2D1O A;  3LQB A;  3B8Z A;  4R3V A;  4XM8 A;  1B8Y A;  1R55 A;  4DD8 A;  5I4O A;  1XFZ A;  2I47 A;  4DV8 A;  1XFW A;  1G9K A;  2HU6 A;  1HOV A;  1ZP5 A;  1KBC A;  4FVL A;  2DDY A;  1IAB A;  1K7G A;  1ZS0 A;  4DF9 A;  1UMT A;  5B5O A;  2OW9 A;  4G9L A;  1USN A;  2MLR A;  1JK3 A;  1D8M A;  3MA2 A;  1AKL A;  2Y6C A;  3DTK A;  830C A;  3I7G A;  4JA1 A;  1Y93 A;  3Q2G A;  4IUW A;  4L6T A;  1J7N A;  1I76 A;  3EDI A;  1GKD A;  4H2E A;  4H82 A;  1BKC A;  3UVC A;  4WKE A;  5I43 A;  3GBO A;  4AUO A;  4CTH A;  2JSD A;  1DTH A;  1MMR A;  5H8X A;  1DMT A;  1EAK A;  1SLN A;  4L63 A;  3EHX A;  3EWJ A;  1OMJ A;  3ZXH A;  3KWV C;  3O64 A;  3K7N A;  3Q2H A;  1R54 A;  2FV9 A;  2USN A;  1CGF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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