5I0LA

Crystal structure of the catalytic domain of mmp-12 in complex with a selective sugar-conjugated arylsulfonamide carboxylate water-soluble inhibitor (dc27).
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
158
structure length
158
Chain Sequence
GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 48
structure length 158
sequence length 158
chains with identical sequence B
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2016-02-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 5i0lA00
1XFXA 1HV5A 3HBUP 3B92A 2AYKA 4WF6A 3EDHA 3TVCA 4AXQA 3LEAA 5I0LA 4XBHA 4JQGA 4H76A 1JAPA 1BQQM 1O0QA 1ZXVA 3HDBA 1BKCA 1JIWP 3F19A 4R3VA 5BPAA 1SATA 3OHLA 3Q2HA 3K7NA 2X3AA 1A86A 2JSDA 1JJ9A 1R55A 1R1JA 1MMRA 1OO9A 3KEJA 3TT4A 1XFWA 5B5OA 3RTSA 5I2ZA 1USNA 2MZEA 2XS3A 3LKAA 1D5JA 3LILA 3SHIA 1DTHA 4I03A 4JPAA 4L63A 3F18A 1KUFA 2OW2A 1OM6A 3EHXA 3UVCA 1AF0A 1FM1A 5L79A 1KBCA 5CXAA 3HYGA 2MZHA 1PWVA 4GR3A 4JA1A 1SU3A 3I7IA 4FU4A 1IAGA 4H82A 2WO8A 2MZIA 1ATLA 1SLNA 1UEAA 1MNCA 4EFSA 3CKIA 1MMPA 1CGFA 3RTTA 1JIZA 1EAKA 1UTTA 4L19A 1FLSA 4XM6A 2DDFA 5I3MA 4GR0A 1GO7P 2X3BA 1CIZA 1RM8A 4DD8A 4H3XA 3L0VA 1GE5A 2Z2DA 4ZR5A 1C3IA 1R1HA 1Y0VA 2W13A 1A85A 3LUNA 3P1VA 1QIBA 3F15A 2N8RA 1B8YA 1SLMA 2XS4A 5H8XA 2W0DA 3V96B 1BSWA 3P24A 2W12A 1CGEA 5B5PA 3HY7A 1CQRA 4G0DA 1ZTQA 2WO9A 1BIWA 1XFYA 4H84A 1GKDA 2CLTA 1KUHA 5BOYA 3NX7A 5D1SA 1AYKA 3LQ0A 1HFSA 1YP1A 3O2XA 1EB6A 3KMEA 1GKCA 2JNPA 1K7IA 1G4KA 1WNIA 1C8TA 2J83A 3ZUKA 1JKYA 1R54A 3U1RA 4PKRA 4WKIA 4XCTA 1L6JA 1OM8A 3MA2A 1Q3AA 1JANA 1OS9A 4H2EA 4DF9A 1ZXCA 4GWMA 2OVXA 5I43A 2ERQA 2D1NA 4JP4A 2RJQA 1KUKA 1UTZA 3KWVC 5LABA 2MLSA 1ND1A 1EUBA 4JIJA 3L0TA 4A7BA 2Y6DA 3GBOA 4PKTA 2ERPA 2FV5A 3KEKA 2DW1A 1SMPA 3AYKA 1H71P 1Z3JA 1KUIA 1JAQA 1DMTA 3DSLA 5D1TA 3KRYA 2CKIA 3LJGA 4GWNA 1PWQA 1BKCE 3LQBA 1IAEA 1XFZA 1PWPA 4GF1A 2I47A 1JH1A 1I73A 1I76A 3DNGA 3F17A 5CZMA 2DW2A 3ZVSA 4J4MA 3DPFA 3AYUA 1HY7A 3LUMA 1XURA 1C7KA 1GXDA 3B2ZA 2OZRA 3EWJA 2OVZA 1D8MA 2X3CA 3K7LA 3LIKA 1BUVM 4WZVA 3EHYA 5JMYA 1IAAA 4I35A 2W14A 1MMBA 2HU6A 4AYKA 966CA 3KHIA 3LE9A 4XM8A 3HY9A 1IACA 1Y93A 5L7FA 4A3WA 1QJJA 1XUDA 1BZSA 4HX3A 1HOVA 3LK8A 1OMJA 3VI1A 4ON1A 1K7QA 2YB9A 1XFUA 1ZS0A 1ZVXA 830CA 2OXZA 3WV1A 1I1IP 4IUWA 1D7XA 1HFCA 2E2DA 1BQOA 2OW1A 3G5CA 3F1AA 1OM7A 3WV2A 1BUDA 3BA0A 1KAPP 1FBLA 4CTHA 4PKWA 3KECA 1XUCA 4QKZA 2OY4A 3DL1A 1OS2A 3LGPA 1ZP5A 2E3XA 3OHOA 2K9CA 1J7NA 4PKSA 2W15A 1MMQA 1D8FA 2L0RA 1Y8JA 1CK7A 2OW9A 2PJTA 2D1OA 5BOTA 4DV8A 1CAQA 1PWUA 4GQLA 1G05A 3N2UA 1K7GA 2OXWA 2SRTA 2WOAA 2O3EA 4H49A 2KRJA 4L6TA 4ILWD 3N2VA 4IN9A 1BKCI 3DWBA 3LMCA 5D2BA 1ASTA 1IADA 3F16A 1XFVA 1BM6A 2JT5A 2J0TA 3LIRA 4FVLA 1QJIA 2USNA 2V4BA 2FV9A 3G42A 2A8HA 2AIGP 1G9KA 4GR8A 4GUYA 2JT6A 4DPEA 1YOUA 4XM7A 2OW0A 2DDYA 3ZXHA 3LJZA 2O36A 1GO8P 4H1QA 1HTDA 3EDGA 4G9LA 1CXVA 3KMCA 1UMTA 1GE7A 4H30A 1JK3A 2RJPA 2QPJA 1UMSA 4WKEA 2OI0A 3Q2GA 1SRPA 1QUAA 1RMZA 4IJOA 1CGLA 3AIGA 1QIAA 1O0TA 1QICA 1PWWA 2K2GA 4FXQA 4FXYP 1KUGA 3HB2P 1YCMA 3I7GA 2POJA 5CUHA 5I4OA 3EDIA 1AKLA 2EROA 4HMAA 1GE6A 4PKQA 4PKVA 2OXUA 1B3DA 1R1IA 1IABA 3TSKA 2YIGA 5D1UA 3ELMA 5D7WA 5I12A 4WK7A 3WV3A 4Q1LA 2OY2A 3HDAP 1YQYA 1G12A 1ROSA 2JIHA 3HBVP 3E8RA 2MLRA 4AUOA 1S4BP 3O64A 3TS4A 1JAOA 2X7MA 2Y6CA 3USNA 4PKUA 5D3CA 1G49A 3DPEA 3LJTA 4AIGA 3B8ZA 456CA 3EDZA 3VTGA 2DW0A 2TCLA
chains in the Genus database with same CATH superfamily
1XFXA 1HV5A 3HBUP 3B92A 2AYKA 4WF6A 3EDHA 3TVCA 4AXQA 3LEAA 5I0LA 4XBHA 4JQGA 4H76A 1JAPA 1BQQM 1O0QA 1ZXVA 3HDBA 1BKCA 1JIWP 3F19A 4R3VA 5BPAA 1SATA 3OHLA 3Q2HA 3K7NA 2X3AA 1A86A 2JSDA 1JJ9A 1R55A 1R1JA 3DTIA 1MMRA 1OO9A 3KEJA 3TT4A 1XFWA 5B5OA 3RTSA 5I2ZA 1USNA 2MZEA 2XS3A 3LKAA 1D5JA 3LILA 3SHIA 1DTHA 4I03A 4JPAA 4L63A 3F18A 1KUFA 2OW2A 1OM6A 3EHXA 3UVCA 1AF0A 1FM1A 5L79A 1KBCA 5CXAA 3HYGA 2MZHA 1PWVA 4GR3A 4JA1A 1SU3A 3I7IA 4FU4A 1IAGA 4H82A 2WO8A 2MZIA 1ATLA 1SLNA 1UEAA 1MNCA 4EFSA 3CKIA 1MMPA 1CGFA 3RTTA 1JIZA 1EAKA 1UTTA 4L19A 1FLSA 4XM6A 2DDFA 5I3MA 4GR0A 1GO7P 2X3BA 1CIZA 1RM8A 4DD8A 4H3XA 3L0VA 1GE5A 2Z2DA 4ZR5A 1C3IA 1R1HA 1Y0VA 2W13A 1A85A 3LUNA 3P1VA 1QIBA 3F15A 2N8RA 1B8YA 1SLMA 2XS4A 5H8XA 2W0DA 3V96B 1BSWA 3P24A 2W12A 1CGEA 5B5PA 3HY7A 1CQRA 4G0DA 1ZTQA 2WO9A 1BIWA 1XFYA 4H84A 1GKDA 2CLTA 1KUHA 5BOYA 3NX7A 1OZ9A 5D1SA 1AYKA 3LQ0A 1HFSA 1YP1A 3O2XA 1EB6A 3KMEA 1GKCA 2JNPA 1K7IA 1G4KA 1WNIA 1C8TA 2J83A 3ZUKA 1JKYA 1R54A 3U1RA 1TVIA 4PKRA 4WKIA 4XCTA 1L6JA 1OM8A 3MA2A 1Q3AA 1JANA 1OS9A 4H2EA 4DF9A 1ZXCA 4GWMA 2OVXA 2YUFA 5I43A 2ERQA 2D1NA 4JP4A 2RJQA 1KUKA 1UTZA 3KWVC 5LABA 2MLSA 1ND1A 1EUBA 4JIJA 3L0TA 4A7BA 2Y6DA 3GBOA 4PKTA 2ERPA 2FV5A 3KEKA 2DW1A 1SMPA 3AYKA 1H71P 1Z3JA 1KUIA 1JAQA 1DMTA 3DSLA 5D1TA 3KRYA 2CKIA 3LJGA 4GWNA 1PWQA 1BKCE 3LQBA 1IAEA 1XFZA 1PWPA 4GF1A 2I47A 1JH1A 1I73A 1I76A 3DNGA 3F17A 5CZMA 2DW2A 3ZVSA 4J4MA 3DPFA 3AYUA 1HY7A 3LUMA 1XURA 1C7KA 1GXDA 3B2ZA 2OZRA 3EWJA 2OVZA 1D8MA 2X3CA 3K7LA 3LIKA 1BUVM 4WZVA 3EHYA 5JMYA 1IAAA 4I35A 2W14A 1MMBA 2HU6A 4AYKA 966CA 3KHIA 3LE9A 4XM8A 3HY9A 3DTEA 1IACA 1Y93A 5L7FA 4A3WA 1QJJA 1XUDA 1BZSA 4HX3A 1HOVA 3LK8A 1OMJA 3VI1A 4ON1A 1K7QA 2YB9A 1XFUA 1ZS0A 1ZVXA 830CA 2OXZA 3WV1A 1I1IP 4IUWA 1D7XA 1HFCA 2E2DA 1BQOA 2OW1A 3G5CA 3F1AA 1OM7A 1XM5A 3WV2A 1BUDA 3BA0A 1KAPP 1FBLA 4CTHA 4PKWA 3KECA 1XUCA 4QKZA 1XAXA 2OY4A 3DL1A 1OS2A 3LGPA 1ZP5A 2E3XA 3OHOA 2K9CA 1J7NA 4PKSA 2W15A 1MMQA 1D8FA 2L0RA 1Y8JA 1CK7A 2OW9A 2PJTA 2D1OA 5BOTA 4DV8A 1CAQA 1PWUA 4GQLA 1G05A 3N2UA 1K7GA 2OXWA 2SRTA 2WOAA 2O3EA 4H49A 2KRJA 4L6TA 4ILWD 3N2VA 4IN9A 1BKCI 3DWBA 3LMCA 5D2BA 1ASTA 1IADA 3F16A 1XFVA 1BM6A 2JT5A 2J0TA 3LIRA 4FVLA 1QJIA 2USNA 2V4BA 2FV9A 3G42A 2A8HA 2AIGP 1G9KA 4GR8A 4GUYA 2JT6A 4DPEA 1YOUA 4XM7A 2OW0A 2DDYA 3ZXHA 3LJZA 2O36A 1GO8P 4H1QA 1HTDA 3EDGA 4G9LA 1CXVA 3KMCA 1UMTA 1GE7A 4H30A 1JK3A 2RJPA 2QPJA 1UMSA 4WKEA 2OI0A 3Q2GA 1SRPA 1QUAA 1RMZA 4IJOA 1CGLA 3DTKA 3AIGA 1QIAA 1O0TA 1QICA 1PWWA 2K2GA 4FXQA 4FXYP 1KUGA 3HB2P 1YCMA 3I7GA 2POJA 5CUHA 5I4OA 3EDIA 1AKLA 2EROA 4HMAA 1GE6A 4PKQA 4PKVA 2OXUA 1B3DA 1R1IA 1IABA 3TSKA 2YIGA 5D1UA 3ELMA 5D7WA 5I12A 4WK7A 3WV3A 4Q1LA 2OY2A 3HDAP 1YQYA 1G12A 1ROSA 2JIHA 3HBVP 3E8RA 2MLRA 4AUOA 1S4BP 4L7AA 3O64A 3TS4A 1JAOA 2X7MA 2Y6CA 3USNA 4PKUA 5D3CA 1G49A 3DPEA 3LJTA 4AIGA 3B8ZA 456CA 3EDZA 3VTGA 2DW0A 2TCLA
chains in the Genus database with same CATH topology
1XFXA 1HV5A 3HBUP 3B92A 2AYKA 4WF6A 3EDHA 3TVCA 4AXQA 3LEAA 5I0LA 4XBHA 4JQGA 4H76A 1JAPA 1BQQM 1O0QA 1ZXVA 3HDBA 1BKCA 1JIWP 3F19A 4R3VA 5BPAA 1SATA 3OHLA 3Q2HA 3K7NA 2X3AA 1A86A 2JSDA 1JJ9A 1R55A 1R1JA 3DTIA 1MMRA 1OO9A 3KEJA 3TT4A 1XFWA 5B5OA 3RTSA 5I2ZA 1USNA 2MZEA 2XS3A 3LKAA 1D5JA 3LILA 3SHIA 1DTHA 4I03A 4JPAA 4L63A 3F18A 1KUFA 2OW2A 1OM6A 3EHXA 3UVCA 1AF0A 1FM1A 5L79A 1KBCA 5CXAA 3HYGA 2MZHA 1PWVA 4GR3A 4JA1A 1SU3A 3I7IA 4FU4A 1IAGA 4H82A 2WO8A 2MZIA 1ATLA 1SLNA 1UEAA 1MNCA 4EFSA 3CKIA 1MMPA 1CGFA 3RTTA 1JIZA 1EAKA 1UTTA 4L19A 1FLSA 4XM6A 2DDFA 5I3MA 4GR0A 1GO7P 2X3BA 1CIZA 1RM8A 4DD8A 4H3XA 3L0VA 1GE5A 2Z2DA 4ZR5A 1C3IA 1R1HA 1Y0VA 2W13A 1A85A 3LUNA 3P1VA 1QIBA 3F15A 2N8RA 1B8YA 1SLMA 2XS4A 5H8XA 2W0DA 3V96B 1BSWA 3P24A 2W12A 1CGEA 5B5PA 3HY7A 1CQRA 4G0DA 1ZTQA 2WO9A 1BIWA 1XFYA 4H84A 1GKDA 2CLTA 1KUHA 5BOYA 3NX7A 5D1SA 1AYKA 3LQ0A 1HFSA 1YP1A 3O2XA 1EB6A 3KMEA 1GKCA 2JNPA 1K7IA 1G4KA 1WNIA 1C8TA 2J83A 3ZUKA 1JKYA 1R54A 3U1RA 4PKRA 4WKIA 4XCTA 1L6JA 1OM8A 3MA2A 1Q3AA 1JANA 1OS9A 4H2EA 4DF9A 1ZXCA 4GWMA 2OVXA 2YUFA 5I43A 2ERQA 2D1NA 4JP4A 2RJQA 1KUKA 1UTZA 3KWVC 5LABA 2MLSA 1ND1A 1EUBA 4JIJA 3L0TA 4A7BA 2Y6DA 3GBOA 4PKTA 2ERPA 2FV5A 3KEKA 2DW1A 1SMPA 3AYKA 1H71P 1Z3JA 1KUIA 1JAQA 1DMTA 3DSLA 5D1TA 3KRYA 2CKIA 3LJGA 4GWNA 1PWQA 1BKCE 3LQBA 1IAEA 1XFZA 1PWPA 4GF1A 2I47A 1JH1A 1I73A 1I76A 3DNGA 3F17A 5CZMA 2DW2A 3ZVSA 4J4MA 3DPFA 3AYUA 1HY7A 3LUMA 1XURA 1C7KA 1GXDA 3B2ZA 2OZRA 3EWJA 2OVZA 1D8MA 2X3CA 3K7LA 3LIKA 1BUVM 4WZVA 3EHYA 5JMYA 1IAAA 4I35A 2W14A 1MMBA 2HU6A 4AYKA 966CA 3KHIA 3LE9A 4XM8A 3HY9A 3DTEA 1IACA 1Y93A 5L7FA 4A3WA 1QJJA 1XUDA 1BZSA 4HX3A 1HOVA 3LK8A 1OMJA 3VI1A 4ON1A 1K7QA 2YB9A 1XFUA 1ZS0A 1ZVXA 830CA 2OXZA 3WV1A 1I1IP 4IUWA 1D7XA 1HFCA 2E2DA 1BQOA 2OW1A 3G5CA 3F1AA 1OM7A 3WV2A 1BUDA 3BA0A 1KAPP 1FBLA 4CTHA 4PKWA 3KECA 1XUCA 4QKZA 2OY4A 3DL1A 1OS2A 3LGPA 1ZP5A 2E3XA 3OHOA 2K9CA 1J7NA 4PKSA 2W15A 1MMQA 1D8FA 2L0RA 1Y8JA 1CK7A 2OW9A 2PJTA 2D1OA 5BOTA 4DV8A 1CAQA 1PWUA 4GQLA 1G05A 3N2UA 1K7GA 2OXWA 2SRTA 2WOAA 2O3EA 4H49A 2KRJA 4L6TA 4ILWD 3N2VA 4IN9A 1BKCI 3DWBA 3LMCA 5D2BA 1ASTA 1IADA 3F16A 1XFVA 1BM6A 2JT5A 2J0TA 3LIRA 4FVLA 1QJIA 2USNA 2V4BA 2FV9A 3G42A 2A8HA 2AIGP 1G9KA 4GR8A 4GUYA 2JT6A 4DPEA 1YOUA 4XM7A 2OW0A 2DDYA 3ZXHA 3LJZA 2O36A 1GO8P 4H1QA 1HTDA 3EDGA 4G9LA 1CXVA 3KMCA 1UMTA 1GE7A 4H30A 1JK3A 2RJPA 2QPJA 1UMSA 4WKEA 2OI0A 3Q2GA 1SRPA 1QUAA 1RMZA 4IJOA 1CGLA 3DTKA 3AIGA 1QIAA 1O0TA 1QICA 1PWWA 2K2GA 4FXQA 4FXYP 1KUGA 3HB2P 1YCMA 3I7GA 2POJA 5CUHA 5I4OA 3EDIA 1AKLA 2EROA 4HMAA 1GE6A 4PKQA 4PKVA 2OXUA 1B3DA 1R1IA 1IABA 3TSKA 2YIGA 5D1UA 3ELMA 5D7WA 5I12A 4WK7A 3WV3A 4Q1LA 2OY2A 3HDAP 1YQYA 1G12A 1ROSA 2JIHA 3HBVP 3E8RA 2MLRA 4AUOA 1S4BP 4L7AA 3O64A 3TS4A 1JAOA 2X7MA 2Y6CA 3USNA 4PKUA 5D3CA 1G49A 3DPEA 3LJTA 4AIGA 3B8ZA 456CA 3EDZA 3VTGA 2DW0A 2TCLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XFX A;  1HV5 A;  3HBU P;  3B92 A;  2AYK A;  4WF6 A;  3EDH A;  3TVC A;  4AXQ A;  3LEA A;  5I0L A;  4XBH A;  4JQG A;  4H76 A;  1JAP A;  1BQQ M;  1O0Q A;  1ZXV A;  3HDB A;  1BKC A;  1JIW P;  3F19 A;  4R3V A;  5BPA A;  1SAT A;  3OHL A;  3Q2H A;  3K7N A;  2X3A A;  1A86 A;  2JSD A;  1JJ9 A;  1R55 A;  1R1J A;  1MMR A;  1OO9 A;  3KEJ A;  3TT4 A;  1XFW A;  5B5O A;  3RTS A;  5I2Z A;  1USN A;  2MZE A;  2XS3 A;  3LKA A;  1D5J A;  3LIL A;  3SHI A;  1DTH A;  4I03 A;  4JPA A;  4L63 A;  3F18 A;  1KUF A;  2OW2 A;  1OM6 A;  3EHX A;  3UVC A;  1AF0 A;  1FM1 A;  5L79 A;  1KBC A;  5CXA A;  3HYG A;  2MZH A;  1PWV A;  4GR3 A;  4JA1 A;  1SU3 A;  3I7I A;  4FU4 A;  1IAG A;  4H82 A;  2WO8 A;  2MZI A;  1ATL A;  1SLN A;  1UEA A;  1MNC A;  4EFS A;  3CKI A;  1MMP A;  1CGF A;  3RTT A;  1JIZ A;  1EAK A;  1UTT A;  4L19 A;  1FLS A;  4XM6 A;  2DDF A;  5I3M A;  4GR0 A;  1GO7 P;  2X3B A;  1CIZ A;  1RM8 A;  4DD8 A;  4H3X A;  3L0V A;  1GE5 A;  2Z2D A;  4ZR5 A;  1C3I A;  1R1H A;  1Y0V A;  2W13 A;  1A85 A;  3LUN A;  3P1V A;  1QIB A;  3F15 A;  2N8R A;  1B8Y A;  1SLM A;  2XS4 A;  5H8X A;  2W0D A;  3V96 B;  1BSW A;  3P24 A;  2W12 A;  1CGE A;  5B5P A;  3HY7 A;  1CQR A;  4G0D A;  1ZTQ A;  2WO9 A;  1BIW A;  1XFY A;  4H84 A;  1GKD A;  2CLT A;  1KUH A;  5BOY A;  3NX7 A;  5D1S A;  1AYK A;  3LQ0 A;  1HFS A;  1YP1 A;  3O2X A;  1EB6 A;  3KME A;  1GKC A;  2JNP A;  1K7I A;  1G4K A;  1WNI A;  1C8T A;  2J83 A;  3ZUK A;  1JKY A;  1R54 A;  3U1R A;  4PKR A;  4WKI A;  4XCT A;  1L6J A;  1OM8 A;  3MA2 A;  1Q3A A;  1JAN A;  1OS9 A;  4H2E A;  4DF9 A;  1ZXC A;  4GWM A;  2OVX A;  5I43 A;  2ERQ A;  2D1N A;  4JP4 A;  2RJQ A;  1KUK A;  1UTZ A;  3KWV C;  5LAB A;  2MLS A;  1ND1 A;  1EUB A;  4JIJ A;  3L0T A;  4A7B A;  2Y6D A;  3GBO A;  4PKT A;  2ERP A;  2FV5 A;  3KEK A;  2DW1 A;  1SMP A;  3AYK A;  1H71 P;  1Z3J A;  1KUI A;  1JAQ A;  1DMT A;  3DSL A;  5D1T A;  3KRY A;  2CKI A;  3LJG A;  4GWN A;  1PWQ A;  1BKC E;  3LQB A;  1IAE A;  1XFZ A;  1PWP A;  4GF1 A;  2I47 A;  1JH1 A;  1I73 A;  1I76 A;  3DNG A;  3F17 A;  5CZM A;  2DW2 A;  3ZVS A;  4J4M A;  3DPF A;  3AYU A;  1HY7 A;  3LUM A;  1XUR A;  1C7K A;  1GXD A;  3B2Z A;  2OZR A;  3EWJ A;  2OVZ A;  1D8M A;  2X3C A;  3K7L A;  3LIK A;  1BUV M;  4WZV A;  3EHY A;  5JMY A;  1IAA A;  4I35 A;  2W14 A;  1MMB A;  2HU6 A;  4AYK A;  966C A;  3KHI A;  3LE9 A;  4XM8 A;  3HY9 A;  1IAC A;  1Y93 A;  5L7F A;  4A3W A;  1QJJ A;  1XUD A;  1BZS A;  4HX3 A;  1HOV A;  3LK8 A;  1OMJ A;  3VI1 A;  4ON1 A;  1K7Q A;  2YB9 A;  1XFU A;  1ZS0 A;  1ZVX A;  830C A;  2OXZ A;  3WV1 A;  1I1I P;  4IUW A;  1D7X A;  1HFC A;  2E2D A;  1BQO A;  2OW1 A;  3G5C A;  3F1A A;  1OM7 A;  3WV2 A;  1BUD A;  3BA0 A;  1KAP P;  1FBL A;  4CTH A;  4PKW A;  3KEC A;  1XUC A;  4QKZ A;  2OY4 A;  3DL1 A;  1OS2 A;  3LGP A;  1ZP5 A;  2E3X A;  3OHO A;  2K9C A;  1J7N A;  4PKS A;  2W15 A;  1MMQ A;  1D8F A;  2L0R A;  1Y8J A;  1CK7 A;  2OW9 A;  2PJT A;  2D1O A;  5BOT A;  4DV8 A;  1CAQ A;  1PWU A;  4GQL A;  1G05 A;  3N2U A;  1K7G A;  2OXW A;  2SRT A;  2WOA A;  2O3E A;  4H49 A;  2KRJ A;  4L6T A;  4ILW D;  3N2V A;  4IN9 A;  1BKC I;  3DWB A;  3LMC A;  5D2B A;  1AST A;  1IAD A;  3F16 A;  1XFV A;  1BM6 A;  2JT5 A;  2J0T A;  3LIR A;  4FVL A;  1QJI A;  2USN A;  2V4B A;  2FV9 A;  3G42 A;  2A8H A;  2AIG P;  1G9K A;  4GR8 A;  4GUY A;  2JT6 A;  4DPE A;  1YOU A;  4XM7 A;  2OW0 A;  2DDY A;  3ZXH A;  3LJZ A;  2O36 A;  1GO8 P;  4H1Q A;  1HTD A;  3EDG A;  4G9L A;  1CXV A;  3KMC A;  1UMT A;  1GE7 A;  4H30 A;  1JK3 A;  2RJP A;  2QPJ A;  1UMS A;  4WKE A;  2OI0 A;  3Q2G A;  1SRP A;  1QUA A;  1RMZ A;  4IJO A;  1CGL A;  3AIG A;  1QIA A;  1O0T A;  1QIC A;  1PWW A;  2K2G A;  4FXQ A;  4FXY P;  1KUG A;  3HB2 P;  1YCM A;  3I7G A;  2POJ A;  5CUH A;  5I4O A;  3EDI A;  1AKL A;  2ERO A;  4HMA A;  1GE6 A;  4PKQ A;  4PKV A;  2OXU A;  1B3D A;  1R1I A;  1IAB A;  3TSK A;  2YIG A;  5D1U A;  3ELM A;  5D7W A;  5I12 A;  4WK7 A;  3WV3 A;  4Q1L A;  2OY2 A;  3HDA P;  1YQY A;  1G12 A;  1ROS A;  2JIH A;  3HBV P;  3E8R A;  2MLR A;  4AUO A;  1S4B P;  3O64 A;  3TS4 A;  1JAO A;  2X7M A;  2Y6C A;  3USN A;  4PKU A;  5D3C A;  1G49 A;  3DPE A;  3LJT A;  4AIG A;  3B8Z A;  456C A;  3EDZ A;  3VTG A;  2DW0 A;  2TCL A; 
#chains in the Genus database with same CATH topology
 1XFX A;  1HV5 A;  3HBU P;  3B92 A;  2AYK A;  4WF6 A;  3EDH A;  3TVC A;  4AXQ A;  3LEA A;  5I0L A;  4XBH A;  4JQG A;  4H76 A;  1JAP A;  1BQQ M;  1O0Q A;  1ZXV A;  3HDB A;  1BKC A;  1JIW P;  3F19 A;  4R3V A;  5BPA A;  1SAT A;  3OHL A;  3Q2H A;  3K7N A;  2X3A A;  1A86 A;  2JSD A;  1JJ9 A;  1R55 A;  1R1J A;  3DTI A;  1MMR A;  1OO9 A;  3KEJ A;  3TT4 A;  1XFW A;  5B5O A;  3RTS A;  5I2Z A;  1USN A;  2MZE A;  2XS3 A;  3LKA A;  1D5J A;  3LIL A;  3SHI A;  1DTH A;  4I03 A;  4JPA A;  4L63 A;  3F18 A;  1KUF A;  2OW2 A;  1OM6 A;  3EHX A;  3UVC A;  1AF0 A;  1FM1 A;  5L79 A;  1KBC A;  5CXA A;  3HYG A;  2MZH A;  1PWV A;  4GR3 A;  4JA1 A;  1SU3 A;  3I7I A;  4FU4 A;  1IAG A;  4H82 A;  2WO8 A;  2MZI A;  1ATL A;  1SLN A;  1UEA A;  1MNC A;  4EFS A;  3CKI A;  1MMP A;  1CGF A;  3RTT A;  1JIZ A;  1EAK A;  1UTT A;  4L19 A;  1FLS A;  4XM6 A;  2DDF A;  5I3M A;  4GR0 A;  1GO7 P;  2X3B A;  1CIZ A;  1RM8 A;  4DD8 A;  4H3X A;  3L0V A;  1GE5 A;  2Z2D A;  4ZR5 A;  1C3I A;  1R1H A;  1Y0V A;  2W13 A;  1A85 A;  3LUN A;  3P1V A;  1QIB A;  3F15 A;  2N8R A;  1B8Y A;  1SLM A;  2XS4 A;  5H8X A;  2W0D A;  3V96 B;  1BSW A;  3P24 A;  2W12 A;  1CGE A;  5B5P A;  3HY7 A;  1CQR A;  4G0D A;  1ZTQ A;  2WO9 A;  1BIW A;  1XFY A;  4H84 A;  1GKD A;  2CLT A;  1KUH A;  5BOY A;  3NX7 A;  1OZ9 A;  5D1S A;  1AYK A;  3LQ0 A;  1HFS A;  1YP1 A;  3O2X A;  1EB6 A;  3KME A;  1GKC A;  2JNP A;  1K7I A;  1G4K A;  1WNI A;  1C8T A;  2J83 A;  3ZUK A;  1JKY A;  1R54 A;  3U1R A;  1TVI A;  4PKR A;  4WKI A;  4XCT A;  1L6J A;  1OM8 A;  3MA2 A;  1Q3A A;  1JAN A;  1OS9 A;  4H2E A;  4DF9 A;  1ZXC A;  4GWM A;  2OVX A;  2YUF A;  5I43 A;  2ERQ A;  2D1N A;  4JP4 A;  2RJQ A;  1KUK A;  1UTZ A;  3KWV C;  5LAB A;  2MLS A;  1ND1 A;  1EUB A;  4JIJ A;  3L0T A;  4A7B A;  2Y6D A;  3GBO A;  4PKT A;  2ERP A;  2FV5 A;  3KEK A;  2DW1 A;  1SMP A;  3AYK A;  1H71 P;  1Z3J A;  1KUI A;  1JAQ A;  1DMT A;  3DSL A;  5D1T A;  3KRY A;  2CKI A;  3LJG A;  4GWN A;  1PWQ A;  1BKC E;  3LQB A;  1IAE A;  1XFZ A;  1PWP A;  4GF1 A;  2I47 A;  1JH1 A;  1I73 A;  1I76 A;  3DNG A;  3F17 A;  5CZM A;  2DW2 A;  3ZVS A;  4J4M A;  3DPF A;  3AYU A;  1HY7 A;  3LUM A;  1XUR A;  1C7K A;  1GXD A;  3B2Z A;  2OZR A;  3EWJ A;  2OVZ A;  1D8M A;  2X3C A;  3K7L A;  3LIK A;  1BUV M;  4WZV A;  3EHY A;  5JMY A;  1IAA A;  4I35 A;  2W14 A;  1MMB A;  2HU6 A;  4AYK A;  966C A;  3KHI A;  3LE9 A;  4XM8 A;  3HY9 A;  3DTE A;  1IAC A;  1Y93 A;  5L7F A;  4A3W A;  1QJJ A;  1XUD A;  1BZS A;  4HX3 A;  1HOV A;  3LK8 A;  1OMJ A;  3VI1 A;  4ON1 A;  1K7Q A;  2YB9 A;  1XFU A;  1ZS0 A;  1ZVX A;  830C A;  2OXZ A;  3WV1 A;  1I1I P;  4IUW A;  1D7X A;  1HFC A;  2E2D A;  1BQO A;  2OW1 A;  3G5C A;  3F1A A;  1OM7 A;  1XM5 A;  3WV2 A;  1BUD A;  3BA0 A;  1KAP P;  1FBL A;  4CTH A;  4PKW A;  3KEC A;  1XUC A;  4QKZ A;  1XAX A;  2OY4 A;  3DL1 A;  1OS2 A;  3LGP A;  1ZP5 A;  2E3X A;  3OHO A;  2K9C A;  1J7N A;  4PKS A;  2W15 A;  1MMQ A;  1D8F A;  2L0R A;  1Y8J A;  1CK7 A;  2OW9 A;  2PJT A;  2D1O A;  5BOT A;  4DV8 A;  1CAQ A;  1PWU A;  4GQL A;  1G05 A;  3N2U A;  1K7G A;  2OXW A;  2SRT A;  2WOA A;  2O3E A;  4H49 A;  2KRJ A;  4L6T A;  4ILW D;  3N2V A;  4IN9 A;  1BKC I;  3DWB A;  3LMC A;  5D2B A;  1AST A;  1IAD A;  3F16 A;  1XFV A;  1BM6 A;  2JT5 A;  2J0T A;  3LIR A;  4FVL A;  1QJI A;  2USN A;  2V4B A;  2FV9 A;  3G42 A;  2A8H A;  2AIG P;  1G9K A;  4GR8 A;  4GUY A;  2JT6 A;  4DPE A;  1YOU A;  4XM7 A;  2OW0 A;  2DDY A;  3ZXH A;  3LJZ A;  2O36 A;  1GO8 P;  4H1Q A;  1HTD A;  3EDG A;  4G9L A;  1CXV A;  3KMC A;  1UMT A;  1GE7 A;  4H30 A;  1JK3 A;  2RJP A;  2QPJ A;  1UMS A;  4WKE A;  2OI0 A;  3Q2G A;  1SRP A;  1QUA A;  1RMZ A;  4IJO A;  1CGL A;  3DTK A;  3AIG A;  1QIA A;  1O0T A;  1QIC A;  1PWW A;  2K2G A;  4FXQ A;  4FXY P;  1KUG A;  3HB2 P;  1YCM A;  3I7G A;  2POJ A;  5CUH A;  5I4O A;  3EDI A;  1AKL A;  2ERO A;  4HMA A;  1GE6 A;  4PKQ A;  4PKV A;  2OXU A;  1B3D A;  1R1I A;  1IAB A;  3TSK A;  2YIG A;  5D1U A;  3ELM A;  5D7W A;  5I12 A;  4WK7 A;  3WV3 A;  4Q1L A;  2OY2 A;  3HDA P;  1YQY A;  1G12 A;  1ROS A;  2JIH A;  3HBV P;  3E8R A;  2MLR A;  4AUO A;  1S4B P;  4L7A A;  3O64 A;  3TS4 A;  1JAO A;  2X7M A;  2Y6C A;  3USN A;  4PKU A;  5D3C A;  1G49 A;  3DPE A;  3LJT A;  4AIG A;  3B8Z A;  456C A;  3EDZ A;  3VTG A;  2DW0 A;  2TCL A; 
#chains in the Genus database with same CATH homology
 1XFX A;  1HV5 A;  3HBU P;  3B92 A;  2AYK A;  4WF6 A;  3EDH A;  3TVC A;  4AXQ A;  3LEA A;  5I0L A;  4XBH A;  4JQG A;  4H76 A;  1JAP A;  1BQQ M;  1O0Q A;  1ZXV A;  3HDB A;  1BKC A;  1JIW P;  3F19 A;  4R3V A;  5BPA A;  1SAT A;  3OHL A;  3Q2H A;  3K7N A;  2X3A A;  1A86 A;  2JSD A;  1JJ9 A;  1R55 A;  1R1J A;  3DTI A;  1MMR A;  1OO9 A;  3KEJ A;  3TT4 A;  1XFW A;  5B5O A;  3RTS A;  5I2Z A;  1USN A;  2MZE A;  2XS3 A;  3LKA A;  1D5J A;  3LIL A;  3SHI A;  1DTH A;  4I03 A;  4JPA A;  4L63 A;  3F18 A;  1KUF A;  2OW2 A;  1OM6 A;  3EHX A;  3UVC A;  1AF0 A;  1FM1 A;  5L79 A;  1KBC A;  5CXA A;  3HYG A;  2MZH A;  1PWV A;  4GR3 A;  4JA1 A;  1SU3 A;  3I7I A;  4FU4 A;  1IAG A;  4H82 A;  2WO8 A;  2MZI A;  1ATL A;  1SLN A;  1UEA A;  1MNC A;  4EFS A;  3CKI A;  1MMP A;  1CGF A;  3RTT A;  1JIZ A;  1EAK A;  1UTT A;  4L19 A;  1FLS A;  4XM6 A;  2DDF A;  5I3M A;  4GR0 A;  1GO7 P;  2X3B A;  1CIZ A;  1RM8 A;  4DD8 A;  4H3X A;  3L0V A;  1GE5 A;  2Z2D A;  4ZR5 A;  1C3I A;  1R1H A;  1Y0V A;  2W13 A;  1A85 A;  3LUN A;  3P1V A;  1QIB A;  3F15 A;  2N8R A;  1B8Y A;  1SLM A;  2XS4 A;  5H8X A;  2W0D A;  3V96 B;  1BSW A;  3P24 A;  2W12 A;  1CGE A;  5B5P A;  3HY7 A;  1CQR A;  4G0D A;  1ZTQ A;  2WO9 A;  1BIW A;  1XFY A;  4H84 A;  1GKD A;  2CLT A;  1KUH A;  5BOY A;  3NX7 A;  5D1S A;  1AYK A;  3LQ0 A;  1HFS A;  1YP1 A;  3O2X A;  1EB6 A;  3KME A;  1GKC A;  2JNP A;  1K7I A;  1G4K A;  1WNI A;  1C8T A;  2J83 A;  3ZUK A;  1JKY A;  1R54 A;  3U1R A;  4PKR A;  4WKI A;  4XCT A;  1L6J A;  1OM8 A;  3MA2 A;  1Q3A A;  1JAN A;  1OS9 A;  4H2E A;  4DF9 A;  1ZXC A;  4GWM A;  2OVX A;  2YUF A;  5I43 A;  2ERQ A;  2D1N A;  4JP4 A;  2RJQ A;  1KUK A;  1UTZ A;  3KWV C;  5LAB A;  2MLS A;  1ND1 A;  1EUB A;  4JIJ A;  3L0T A;  4A7B A;  2Y6D A;  3GBO A;  4PKT A;  2ERP A;  2FV5 A;  3KEK A;  2DW1 A;  1SMP A;  3AYK A;  1H71 P;  1Z3J A;  1KUI A;  1JAQ A;  1DMT A;  3DSL A;  5D1T A;  3KRY A;  2CKI A;  3LJG A;  4GWN A;  1PWQ A;  1BKC E;  3LQB A;  1IAE A;  1XFZ A;  1PWP A;  4GF1 A;  2I47 A;  1JH1 A;  1I73 A;  1I76 A;  3DNG A;  3F17 A;  5CZM A;  2DW2 A;  3ZVS A;  4J4M A;  3DPF A;  3AYU A;  1HY7 A;  3LUM A;  1XUR A;  1C7K A;  1GXD A;  3B2Z A;  2OZR A;  3EWJ A;  2OVZ A;  1D8M A;  2X3C A;  3K7L A;  3LIK A;  1BUV M;  4WZV A;  3EHY A;  5JMY A;  1IAA A;  4I35 A;  2W14 A;  1MMB A;  2HU6 A;  4AYK A;  966C A;  3KHI A;  3LE9 A;  4XM8 A;  3HY9 A;  3DTE A;  1IAC A;  1Y93 A;  5L7F A;  4A3W A;  1QJJ A;  1XUD A;  1BZS A;  4HX3 A;  1HOV A;  3LK8 A;  1OMJ A;  3VI1 A;  4ON1 A;  1K7Q A;  2YB9 A;  1XFU A;  1ZS0 A;  1ZVX A;  830C A;  2OXZ A;  3WV1 A;  1I1I P;  4IUW A;  1D7X A;  1HFC A;  2E2D A;  1BQO A;  2OW1 A;  3G5C A;  3F1A A;  1OM7 A;  3WV2 A;  1BUD A;  3BA0 A;  1KAP P;  1FBL A;  4CTH A;  4PKW A;  3KEC A;  1XUC A;  4QKZ A;  2OY4 A;  3DL1 A;  1OS2 A;  3LGP A;  1ZP5 A;  2E3X A;  3OHO A;  2K9C A;  1J7N A;  4PKS A;  2W15 A;  1MMQ A;  1D8F A;  2L0R A;  1Y8J A;  1CK7 A;  2OW9 A;  2PJT A;  2D1O A;  5BOT A;  4DV8 A;  1CAQ A;  1PWU A;  4GQL A;  1G05 A;  3N2U A;  1K7G A;  2OXW A;  2SRT A;  2WOA A;  2O3E A;  4H49 A;  2KRJ A;  4L6T A;  4ILW D;  3N2V A;  4IN9 A;  1BKC I;  3DWB A;  3LMC A;  5D2B A;  1AST A;  1IAD A;  3F16 A;  1XFV A;  1BM6 A;  2JT5 A;  2J0T A;  3LIR A;  4FVL A;  1QJI A;  2USN A;  2V4B A;  2FV9 A;  3G42 A;  2A8H A;  2AIG P;  1G9K A;  4GR8 A;  4GUY A;  2JT6 A;  4DPE A;  1YOU A;  4XM7 A;  2OW0 A;  2DDY A;  3ZXH A;  3LJZ A;  2O36 A;  1GO8 P;  4H1Q A;  1HTD A;  3EDG A;  4G9L A;  1CXV A;  3KMC A;  1UMT A;  1GE7 A;  4H30 A;  1JK3 A;  2RJP A;  2QPJ A;  1UMS A;  4WKE A;  2OI0 A;  3Q2G A;  1SRP A;  1QUA A;  1RMZ A;  4IJO A;  1CGL A;  3DTK A;  3AIG A;  1QIA A;  1O0T A;  1QIC A;  1PWW A;  2K2G A;  4FXQ A;  4FXY P;  1KUG A;  3HB2 P;  1YCM A;  3I7G A;  2POJ A;  5CUH A;  5I4O A;  3EDI A;  1AKL A;  2ERO A;  4HMA A;  1GE6 A;  4PKQ A;  4PKV A;  2OXU A;  1B3D A;  1R1I A;  1IAB A;  3TSK A;  2YIG A;  5D1U A;  3ELM A;  5D7W A;  5I12 A;  4WK7 A;  3WV3 A;  4Q1L A;  2OY2 A;  3HDA P;  1YQY A;  1G12 A;  1ROS A;  2JIH A;  3HBV P;  3E8R A;  2MLR A;  4AUO A;  1S4B P;  4L7A A;  3O64 A;  3TS4 A;  1JAO A;  2X7M A;  2Y6C A;  3USN A;  4PKU A;  5D3C A;  1G49 A;  3DPE A;  3LJT A;  4AIG A;  3B8Z A;  456C A;  3EDZ A;  3VTG A;  2DW0 A;  2TCL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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