5BOTA

X-ray co-structure of mmp-13 with ethyl 5-carbamoyl-1h-indole-2-carboxylate
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
169
structure length
166
Chain Sequence
YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGFMLPDDDVQGIQSLYGPGDED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Fragment-based discovery of indole inhibitors of matrix metalloproteinase-13.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Collagenase 3
total genus 44
structure length 166
sequence length 169
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2015-05-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 5botA00
1R1HA 1EB6A 4L63A 3DPFA 1ZXCA 3LK8A 1I1IP 2OXZA 3HDAP 3L0VA 3B92A 1KUHA 4H30A 1HY7A 4H3XA 2W0DA 1I73A 4JPAA 2O36A 1ND1A 2ERQA 4PKUA 1K7IA 1AYKA 3O64A 2DW1A 1OMJA 2WO9A 4G9LA 1OM6A 3I7IA 4EFSA 2W15A 3EDZA 2DDFA 1IAEA 2JIHA 4GUYA 1QIBA 3F16A 1A86A 2JT5A 4GR0A 1G12A 3OHLA 1B8YA 2X3BA 1XFXA 1JKYA 1KAPP 3EDIA 3P1VA 4AXQA 1OM8A 3F18A 3HBUP 3DPEA 4A3WA 4WZVA 3RTTA 1D8FA 4DD8A 1IADA 2CKIA 4PKTA 2XS4A 3EHXA 1GKDA 3ELMA 1B3DA 1D5JA 1HFCA 4WF6A 2A8HA 2OXWA 1XUCA 4FXYP 3TS4A 2RJPA 3KHIA 2W14A 830CA 4XM8A 3F15A 3EWJA 1Y8JA 3B2ZA 3AIGA 2OY4A 2AYKA 3G42A 3G5CA 1FBLA 1HV5A 4H76A 5D1SA 2J0TA 1CIZA 1GKCA 3LKAA 3LEAA 5JMYA 3ZVSA 1OO9A 1YCMA 2AIGP 1C3IA 1QIAA 1ZVXA 5D3CA 1JAQA 1G05A 1SU3A 2JSDA 2KRJA 3LQ0A 4CTHA 3HB2P 1A85A 1MMPA 3EHYA 1D7XA 3HBVP 1IAAA 4JA1A 5I3MA 1MMQA 1R55A 3AYUA 1CGFA 4Q1LA 1O0TA 2I47A 3KWVC 3UVCA 2XS3A 1CGEA 5D7WA 1YOUA 1Q3AA 3KECA 1GXDA 2E3XA 1EUBA 1OS9A 3LGPA 4IUWA 4XM7A 3I7GA 1MMRA 1RMZA 3DNGA 1Z3JA 3LJZA 2JNPA 2D1NA 1KUIA 5B5OA 4IN9A 1CGLA 3EDGA 5D1UA 1JH1A 1IAGA 1R1JA 4JIJA 2X7MA 3Q2HA 4A7BA 1XFUA 1I76A 4PKVA 1DTHA 966CA 1K7GA 1ATLA 5D2BA 1C8TA 3L0TA 456CA 3DL1A 1CK7A 2MLSA 5B5PA 1KUGA 1Y0VA 1YQYA 1JK3A 3WV1A 1SLNA 3OHOA 1XUDA 4L6TA 2MLRA 3WV3A 1BIWA 2OW2A 2OW0A 4WKEA 3MA2A 4XCTA 4GWMA 1JJ9A 5I0LA 1ASTA 2Z2DA 3TVCA 2OVXA 3N2VA 2MZIA 3LUMA 1XURA 3BA0A 3VI1A 4H2EA 1SMPA 3VTGA 4FXQA 2K9CA 5L79A 5BPAA 4FU4A 1ZXVA 1BQOA 5I43A 3EDHA 4PKRA 1BZSA 3LUNA 1G49A 1R1IA 4QKZA 3RTSA 1QICA 1XFYA 2K2GA 4AUOA 4HMAA 2MZEA 1IABA 3F17A 3LILA 2J83A 3DSLA 1ZP5A 1JANA 2QPJA 2SRTA 1HTDA 1PWWA 3HY9A 3KEJA 4ZR5A 3KEKA 4GWNA 1MMBA 2DDYA 2FV9A 3AYKA 1XFWA 2WO8A 4JQGA 1PWQA 2EROA 1UMTA 1OM7A 1AF0A 1IACA 2CLTA 1PWVA 1GE6A 1MNCA 2YIGA 2O3EA 2V4BA 5I12A 3N2UA 4I35A 4AIGA 1DMTA 1ZTQA 3KMEA 1R54A 2OW1A 3LQBA 4JP4A 3LIRA 2W13A 1PWUA 3Q2GA 4AYKA 3NX7A 1SRPA 4ILWD 1GE5A 1BUDA 1GO8P 1ROSA 1G4KA 1D8MA 1BQQM 3F1AA 2OZRA 3KMCA 3K7NA 1SATA 1KUKA 1L6JA 4FVLA 3K7LA 4HX3A 1PWPA 1FLSA 3O2XA 4XM6A 1OS2A 1HOVA 2N8RA 1O0QA 5BOTA 2OW9A 1QUAA 2JT6A 1JIZA 4PKWA 3HDBA 2USNA 3SHIA 2MZHA 2E2DA 2HU6A 1HFSA 4H49A 4H82A 3GBOA 4ON1A 1JAPA 2FV5A 3LJTA 1XFVA 5CXAA 2WOAA 4GR8A 3LJGA 2D1OA 4GQLA 1XFZA 4PKSA 2DW0A 2YB9A 3P24A 5D1TA 2DW2A 1ZS0A 3LIKA 3F19A 2OY2A 1QJJA 5L7FA 3USNA 3ZXHA 3HYGA 1BKCE 3WV2A 4WKIA 5CUHA 1GO7P 3ZUKA 3KRYA 2TCLA 1UTZA 1C7KA 1G9KA 2L0RA 1CAQA 5I4OA 1UEAA 1CQRA 4DV8A 1K7QA 4DPEA 1S4BP 4IJOA 3TT4A 3LMCA 4H84A 1BUVM 1USNA 1KBCA 2RJQA 2ERPA 3HY7A 1UMSA 1AKLA 2OI0A 2OXUA 1H71P 2OVZA 2W12A 2PJTA 1UTTA 5H8XA 5LABA 2X3CA 3CKIA 3U1RA 2Y6DA 1Y93A 1YP1A 4GF1A 5I2ZA 3V96B 2POJA 4J4MA 4PKQA 5BOYA 4DF9A 4H1QA 1JIWP 1J7NA 1KUFA 2Y6CA 1JAOA 1BKCA 1WNIA 4XBHA 1FM1A 4G0DA 1CXVA 1SLMA 1EAKA 1GE7A 4L19A 4WK7A 1BM6A 3B8ZA 1BKCI 4GR3A 4I03A 1BSWA 3DWBA 3LE9A 1QJIA 4R3VA 3TSKA 1RM8A 5CZMA 2X3AA 3E8RA
chains in the Genus database with same CATH superfamily
1R1HA 1EB6A 4L63A 3DPFA 1ZXCA 3LK8A 1I1IP 2OXZA 3HDAP 1OZ9A 3L0VA 3B92A 1KUHA 4H30A 1HY7A 4H3XA 2W0DA 1I73A 4JPAA 2O36A 1ND1A 2ERQA 4PKUA 1K7IA 1AYKA 3O64A 2DW1A 1OMJA 2WO9A 4G9LA 1OM6A 3I7IA 4EFSA 2W15A 3EDZA 2DDFA 1IAEA 2JIHA 4GUYA 1QIBA 3F16A 1A86A 2JT5A 4GR0A 1G12A 1XM5A 3OHLA 1B8YA 2X3BA 1XFXA 1JKYA 1KAPP 3DTEA 3EDIA 3P1VA 4AXQA 1OM8A 3F18A 1TVIA 3DPEA 3HBUP 4A3WA 4WZVA 3RTTA 1D8FA 4DD8A 1IADA 2CKIA 4PKTA 2XS4A 3EHXA 1GKDA 3ELMA 1B3DA 1D5JA 1HFCA 4WF6A 2A8HA 2OXWA 1XUCA 4FXYP 3TS4A 2RJPA 3KHIA 2W14A 3DTIA 830CA 4XM8A 3F15A 3EWJA 1Y8JA 3B2ZA 3AIGA 2OY4A 2AYKA 3G42A 3G5CA 1FBLA 1HV5A 4H76A 5D1SA 2J0TA 1CIZA 1GKCA 3LKAA 3LEAA 5JMYA 3ZVSA 1OO9A 1YCMA 2AIGP 1C3IA 1QIAA 1ZVXA 5D3CA 1JAQA 1G05A 1SU3A 2JSDA 2KRJA 3LQ0A 4CTHA 3HB2P 1A85A 1MMPA 3EHYA 1D7XA 3HBVP 1IAAA 4JA1A 5I3MA 1MMQA 1R55A 3AYUA 1CGFA 4Q1LA 1O0TA 2I47A 3KWVC 3UVCA 2XS3A 1CGEA 5D7WA 1YOUA 1Q3AA 3KECA 1GXDA 2E3XA 1EUBA 1OS9A 3LGPA 4IUWA 4XM7A 3I7GA 1MMRA 1RMZA 3DNGA 1Z3JA 3LJZA 2JNPA 2D1NA 1KUIA 5B5OA 4IN9A 1CGLA 3EDGA 5D1UA 1JH1A 1IAGA 1R1JA 4JIJA 2X7MA 3Q2HA 4A7BA 1XFUA 1I76A 4PKVA 1DTHA 966CA 1K7GA 1ATLA 5D2BA 1C8TA 3L0TA 456CA 3DL1A 1CK7A 2MLSA 5B5PA 4L7AA 1KUGA 1Y0VA 1YQYA 1JK3A 3WV1A 1SLNA 3OHOA 1XUDA 4L6TA 2MLRA 3WV3A 1BIWA 2OW2A 2OW0A 4WKEA 3MA2A 4XCTA 4GWMA 1JJ9A 5I0LA 1ASTA 2Z2DA 3TVCA 2OVXA 3N2VA 2MZIA 3LUMA 1XURA 3BA0A 3VI1A 4H2EA 1SMPA 1XAXA 3VTGA 4FXQA 2K9CA 5L79A 5BPAA 4FU4A 1ZXVA 1BQOA 5I43A 3EDHA 4PKRA 1BZSA 3LUNA 1G49A 1R1IA 4QKZA 3RTSA 1QICA 1XFYA 2K2GA 4AUOA 4HMAA 2MZEA 1IABA 3F17A 3LILA 2J83A 3DSLA 1ZP5A 1JANA 2QPJA 2SRTA 1HTDA 1PWWA 3HY9A 3KEJA 4ZR5A 3KEKA 4GWNA 1MMBA 2DDYA 2FV9A 3AYKA 1XFWA 2WO8A 4JQGA 1PWQA 2EROA 1UMTA 1OM7A 1AF0A 1IACA 2CLTA 1PWVA 1GE6A 1MNCA 2YIGA 2O3EA 2V4BA 5I12A 3N2UA 4I35A 4AIGA 1DMTA 1ZTQA 3KMEA 1R54A 2OW1A 3LQBA 4JP4A 3LIRA 2W13A 2YUFA 1PWUA 3Q2GA 4AYKA 3NX7A 1SRPA 4ILWD 1GE5A 1BUDA 1GO8P 1ROSA 1G4KA 1D8MA 1BQQM 3F1AA 2OZRA 3KMCA 3K7NA 1SATA 1KUKA 1L6JA 4FVLA 3K7LA 4HX3A 1PWPA 1FLSA 3O2XA 4XM6A 1OS2A 1HOVA 2N8RA 1O0QA 5BOTA 2OW9A 1QUAA 2JT6A 1JIZA 4PKWA 3HDBA 2USNA 3SHIA 2MZHA 2E2DA 2HU6A 1HFSA 3DTKA 4H49A 4H82A 3GBOA 4ON1A 1JAPA 2FV5A 3LJTA 1XFVA 5CXAA 2WOAA 4GR8A 3LJGA 2D1OA 4GQLA 1XFZA 4PKSA 2DW0A 2YB9A 3P24A 5D1TA 2DW2A 1ZS0A 3LIKA 3F19A 2OY2A 1QJJA 5L7FA 3USNA 3ZXHA 3HYGA 1BKCE 3WV2A 4WKIA 5CUHA 1GO7P 3ZUKA 3KRYA 2TCLA 1UTZA 1C7KA 1G9KA 2L0RA 1CAQA 5I4OA 1UEAA 1CQRA 4DV8A 1K7QA 4DPEA 1S4BP 4IJOA 3TT4A 3LMCA 4H84A 1BUVM 1USNA 1KBCA 2RJQA 2ERPA 3HY7A 1UMSA 1AKLA 2OI0A 2OXUA 1H71P 2OVZA 2W12A 2PJTA 1UTTA 5H8XA 5LABA 2X3CA 3CKIA 3U1RA 2Y6DA 1Y93A 1YP1A 4GF1A 5I2ZA 3V96B 2POJA 4J4MA 4PKQA 5BOYA 4DF9A 4H1QA 1JIWP 1J7NA 1KUFA 2Y6CA 1JAOA 1BKCA 1WNIA 4XBHA 1FM1A 4G0DA 1CXVA 1SLMA 1EAKA 1GE7A 4L19A 4WK7A 1BM6A 3B8ZA 1BKCI 4GR3A 4I03A 1BSWA 3DWBA 3LE9A 1QJIA 4R3VA 3TSKA 1RM8A 5CZMA 2X3AA 3E8RA
chains in the Genus database with same CATH topology
1R1HA 1EB6A 4L63A 3DPFA 1ZXCA 3LK8A 1I1IP 2OXZA 3HDAP 3L0VA 3B92A 1KUHA 4H30A 1HY7A 4H3XA 2W0DA 1I73A 4JPAA 2O36A 1ND1A 2ERQA 4PKUA 1K7IA 1AYKA 3O64A 2DW1A 1OMJA 2WO9A 4G9LA 1OM6A 3I7IA 4EFSA 2W15A 3EDZA 2DDFA 1IAEA 2JIHA 4GUYA 1QIBA 3F16A 1A86A 2JT5A 4GR0A 1G12A 3OHLA 1B8YA 2X3BA 1XFXA 1JKYA 1KAPP 3DTEA 3EDIA 3P1VA 4AXQA 1OM8A 3F18A 3HBUP 3DPEA 4A3WA 4WZVA 3RTTA 1D8FA 4DD8A 1IADA 2CKIA 4PKTA 2XS4A 3EHXA 1GKDA 3ELMA 1B3DA 1D5JA 1HFCA 4WF6A 2A8HA 2OXWA 1XUCA 4FXYP 3TS4A 2RJPA 3KHIA 2W14A 3DTIA 830CA 4XM8A 3F15A 3EWJA 1Y8JA 3B2ZA 3AIGA 2OY4A 2AYKA 3G42A 3G5CA 1FBLA 1HV5A 4H76A 5D1SA 2J0TA 1CIZA 1GKCA 3LKAA 3LEAA 5JMYA 3ZVSA 1OO9A 1YCMA 2AIGP 1C3IA 1QIAA 1ZVXA 5D3CA 1JAQA 1G05A 1SU3A 2JSDA 2KRJA 3LQ0A 4CTHA 3HB2P 1A85A 1MMPA 3EHYA 1D7XA 3HBVP 1IAAA 4JA1A 5I3MA 1MMQA 1R55A 3AYUA 1CGFA 4Q1LA 1O0TA 2I47A 3KWVC 3UVCA 2XS3A 1CGEA 5D7WA 1YOUA 1Q3AA 3KECA 1GXDA 2E3XA 1EUBA 1OS9A 3LGPA 4IUWA 4XM7A 3I7GA 1MMRA 1RMZA 3DNGA 1Z3JA 3LJZA 2JNPA 2D1NA 1KUIA 5B5OA 4IN9A 1CGLA 3EDGA 5D1UA 1JH1A 1IAGA 1R1JA 4JIJA 2X7MA 3Q2HA 4A7BA 1XFUA 1I76A 4PKVA 1DTHA 966CA 1K7GA 1ATLA 5D2BA 1C8TA 3L0TA 456CA 3DL1A 1CK7A 2MLSA 5B5PA 4L7AA 1KUGA 1Y0VA 1YQYA 1JK3A 3WV1A 1SLNA 3OHOA 1XUDA 4L6TA 2MLRA 3WV3A 1BIWA 2OW2A 2OW0A 4WKEA 3MA2A 4XCTA 4GWMA 1JJ9A 5I0LA 1ASTA 2Z2DA 3TVCA 2OVXA 3N2VA 2MZIA 3LUMA 1XURA 3BA0A 3VI1A 4H2EA 1SMPA 3VTGA 4FXQA 2K9CA 5L79A 5BPAA 4FU4A 1ZXVA 1BQOA 5I43A 3EDHA 4PKRA 1BZSA 3LUNA 1G49A 1R1IA 4QKZA 3RTSA 1QICA 1XFYA 2K2GA 4AUOA 4HMAA 2MZEA 1IABA 3F17A 3LILA 2J83A 3DSLA 1ZP5A 1JANA 2QPJA 2SRTA 1HTDA 1PWWA 3HY9A 3KEJA 4ZR5A 3KEKA 4GWNA 1MMBA 2DDYA 2FV9A 3AYKA 1XFWA 2WO8A 4JQGA 1PWQA 2EROA 1UMTA 1OM7A 1AF0A 1IACA 2CLTA 1PWVA 1GE6A 1MNCA 2YIGA 2O3EA 2V4BA 5I12A 3N2UA 4I35A 4AIGA 1DMTA 1ZTQA 3KMEA 1R54A 2OW1A 3LQBA 4JP4A 3LIRA 2W13A 2YUFA 1PWUA 3Q2GA 4AYKA 3NX7A 1SRPA 4ILWD 1GE5A 1BUDA 1GO8P 1ROSA 1G4KA 1D8MA 1BQQM 3F1AA 2OZRA 3KMCA 3K7NA 1SATA 1KUKA 1L6JA 4FVLA 3K7LA 4HX3A 1PWPA 1FLSA 3O2XA 4XM6A 1OS2A 1HOVA 2N8RA 1O0QA 5BOTA 2OW9A 1QUAA 2JT6A 1JIZA 4PKWA 3HDBA 2USNA 3SHIA 2MZHA 2E2DA 2HU6A 1HFSA 3DTKA 4H49A 4H82A 3GBOA 4ON1A 1JAPA 2FV5A 3LJTA 1XFVA 5CXAA 2WOAA 4GR8A 3LJGA 2D1OA 4GQLA 1XFZA 4PKSA 2DW0A 2YB9A 3P24A 5D1TA 2DW2A 1ZS0A 3LIKA 3F19A 2OY2A 1QJJA 5L7FA 3USNA 3ZXHA 3HYGA 1BKCE 3WV2A 4WKIA 5CUHA 1GO7P 3ZUKA 3KRYA 2TCLA 1UTZA 1C7KA 1G9KA 2L0RA 1CAQA 5I4OA 1UEAA 1CQRA 4DV8A 1K7QA 4DPEA 1S4BP 4IJOA 3TT4A 3LMCA 4H84A 1BUVM 1USNA 1KBCA 2RJQA 2ERPA 3HY7A 1UMSA 1AKLA 2OI0A 2OXUA 1H71P 2OVZA 2W12A 2PJTA 1UTTA 5H8XA 5LABA 2X3CA 3CKIA 3U1RA 2Y6DA 1Y93A 1YP1A 4GF1A 5I2ZA 3V96B 2POJA 4J4MA 4PKQA 5BOYA 4DF9A 4H1QA 1JIWP 1J7NA 1KUFA 2Y6CA 1JAOA 1BKCA 1WNIA 4XBHA 1FM1A 4G0DA 1CXVA 1SLMA 1EAKA 1GE7A 4L19A 4WK7A 1BM6A 3B8ZA 1BKCI 4GR3A 4I03A 1BSWA 3DWBA 3LE9A 1QJIA 4R3VA 3TSKA 1RM8A 5CZMA 2X3AA 3E8RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R1H A;  1EB6 A;  4L63 A;  3DPF A;  1ZXC A;  3LK8 A;  1I1I P;  2OXZ A;  3HDA P;  3L0V A;  3B92 A;  1KUH A;  4H30 A;  1HY7 A;  4H3X A;  2W0D A;  1I73 A;  4JPA A;  2O36 A;  1ND1 A;  2ERQ A;  4PKU A;  1K7I A;  1AYK A;  3O64 A;  2DW1 A;  1OMJ A;  2WO9 A;  4G9L A;  1OM6 A;  3I7I A;  4EFS A;  2W15 A;  3EDZ A;  2DDF A;  1IAE A;  2JIH A;  4GUY A;  1QIB A;  3F16 A;  1A86 A;  2JT5 A;  4GR0 A;  1G12 A;  3OHL A;  1B8Y A;  2X3B A;  1XFX A;  1JKY A;  1KAP P;  3EDI A;  3P1V A;  4AXQ A;  1OM8 A;  3F18 A;  3HBU P;  3DPE A;  4A3W A;  4WZV A;  3RTT A;  1D8F A;  4DD8 A;  1IAD A;  2CKI A;  4PKT A;  2XS4 A;  3EHX A;  1GKD A;  3ELM A;  1B3D A;  1D5J A;  1HFC A;  4WF6 A;  2A8H A;  2OXW A;  1XUC A;  4FXY P;  3TS4 A;  2RJP A;  3KHI A;  2W14 A;  830C A;  4XM8 A;  3F15 A;  3EWJ A;  1Y8J A;  3B2Z A;  3AIG A;  2OY4 A;  2AYK A;  3G42 A;  3G5C A;  1FBL A;  1HV5 A;  4H76 A;  5D1S A;  2J0T A;  1CIZ A;  1GKC A;  3LKA A;  3LEA A;  5JMY A;  3ZVS A;  1OO9 A;  1YCM A;  2AIG P;  1C3I A;  1QIA A;  1ZVX A;  5D3C A;  1JAQ A;  1G05 A;  1SU3 A;  2JSD A;  2KRJ A;  3LQ0 A;  4CTH A;  3HB2 P;  1A85 A;  1MMP A;  3EHY A;  1D7X A;  3HBV P;  1IAA A;  4JA1 A;  5I3M A;  1MMQ A;  1R55 A;  3AYU A;  1CGF A;  4Q1L A;  1O0T A;  2I47 A;  3KWV C;  3UVC A;  2XS3 A;  1CGE A;  5D7W A;  1YOU A;  1Q3A A;  3KEC A;  1GXD A;  2E3X A;  1EUB A;  1OS9 A;  3LGP A;  4IUW A;  4XM7 A;  3I7G A;  1MMR A;  1RMZ A;  3DNG A;  1Z3J A;  3LJZ A;  2JNP A;  2D1N A;  1KUI A;  5B5O A;  4IN9 A;  1CGL A;  3EDG A;  5D1U A;  1JH1 A;  1IAG A;  1R1J A;  4JIJ A;  2X7M A;  3Q2H A;  4A7B A;  1XFU A;  1I76 A;  4PKV A;  1DTH A;  966C A;  1K7G A;  1ATL A;  5D2B A;  1C8T A;  3L0T A;  456C A;  3DL1 A;  1CK7 A;  2MLS A;  5B5P A;  1KUG A;  1Y0V A;  1YQY A;  1JK3 A;  3WV1 A;  1SLN A;  3OHO A;  1XUD A;  4L6T A;  2MLR A;  3WV3 A;  1BIW A;  2OW2 A;  2OW0 A;  4WKE A;  3MA2 A;  4XCT A;  4GWM A;  1JJ9 A;  5I0L A;  1AST A;  2Z2D A;  3TVC A;  2OVX A;  3N2V A;  2MZI A;  3LUM A;  1XUR A;  3BA0 A;  3VI1 A;  4H2E A;  1SMP A;  3VTG A;  4FXQ A;  2K9C A;  5L79 A;  5BPA A;  4FU4 A;  1ZXV A;  1BQO A;  5I43 A;  3EDH A;  4PKR A;  1BZS A;  3LUN A;  1G49 A;  1R1I A;  4QKZ A;  3RTS A;  1QIC A;  1XFY A;  2K2G A;  4AUO A;  4HMA A;  2MZE A;  1IAB A;  3F17 A;  3LIL A;  2J83 A;  3DSL A;  1ZP5 A;  1JAN A;  2QPJ A;  2SRT A;  1HTD A;  1PWW A;  3HY9 A;  3KEJ A;  4ZR5 A;  3KEK A;  4GWN A;  1MMB A;  2DDY A;  2FV9 A;  3AYK A;  1XFW A;  2WO8 A;  4JQG A;  1PWQ A;  2ERO A;  1UMT A;  1OM7 A;  1AF0 A;  1IAC A;  2CLT A;  1PWV A;  1GE6 A;  1MNC A;  2YIG A;  2O3E A;  2V4B A;  5I12 A;  3N2U A;  4I35 A;  4AIG A;  1DMT A;  1ZTQ A;  3KME A;  1R54 A;  2OW1 A;  3LQB A;  4JP4 A;  3LIR A;  2W13 A;  1PWU A;  3Q2G A;  4AYK A;  3NX7 A;  1SRP A;  4ILW D;  1GE5 A;  1BUD A;  1GO8 P;  1ROS A;  1G4K A;  1D8M A;  1BQQ M;  3F1A A;  2OZR A;  3KMC A;  3K7N A;  1SAT A;  1KUK A;  1L6J A;  4FVL A;  3K7L A;  4HX3 A;  1PWP A;  1FLS A;  3O2X A;  4XM6 A;  1OS2 A;  1HOV A;  2N8R A;  1O0Q A;  5BOT A;  2OW9 A;  1QUA A;  2JT6 A;  1JIZ A;  4PKW A;  3HDB A;  2USN A;  3SHI A;  2MZH A;  2E2D A;  2HU6 A;  1HFS A;  4H49 A;  4H82 A;  3GBO A;  4ON1 A;  1JAP A;  2FV5 A;  3LJT A;  1XFV A;  5CXA A;  2WOA A;  4GR8 A;  3LJG A;  2D1O A;  4GQL A;  1XFZ A;  4PKS A;  2DW0 A;  2YB9 A;  3P24 A;  5D1T A;  2DW2 A;  1ZS0 A;  3LIK A;  3F19 A;  2OY2 A;  1QJJ A;  5L7F A;  3USN A;  3ZXH A;  3HYG A;  1BKC E;  3WV2 A;  4WKI A;  5CUH A;  1GO7 P;  3ZUK A;  3KRY A;  2TCL A;  1UTZ A;  1C7K A;  1G9K A;  2L0R A;  1CAQ A;  5I4O A;  1UEA A;  1CQR A;  4DV8 A;  1K7Q A;  4DPE A;  1S4B P;  4IJO A;  3TT4 A;  3LMC A;  4H84 A;  1BUV M;  1USN A;  1KBC A;  2RJQ A;  2ERP A;  3HY7 A;  1UMS A;  1AKL A;  2OI0 A;  2OXU A;  1H71 P;  2OVZ A;  2W12 A;  2PJT A;  1UTT A;  5H8X A;  5LAB A;  2X3C A;  3CKI A;  3U1R A;  2Y6D A;  1Y93 A;  1YP1 A;  4GF1 A;  5I2Z A;  3V96 B;  2POJ A;  4J4M A;  4PKQ A;  5BOY A;  4DF9 A;  4H1Q A;  1JIW P;  1J7N A;  1KUF A;  2Y6C A;  1JAO A;  1BKC A;  1WNI A;  4XBH A;  1FM1 A;  4G0D A;  1CXV A;  1SLM A;  1EAK A;  1GE7 A;  4L19 A;  4WK7 A;  1BM6 A;  3B8Z A;  1BKC I;  4GR3 A;  4I03 A;  1BSW A;  3DWB A;  3LE9 A;  1QJI A;  4R3V A;  3TSK A;  1RM8 A;  5CZM A;  2X3A A;  3E8R A; 
#chains in the Genus database with same CATH topology
 1R1H A;  1EB6 A;  4L63 A;  3DPF A;  1ZXC A;  3LK8 A;  1I1I P;  2OXZ A;  3HDA P;  1OZ9 A;  3L0V A;  3B92 A;  1KUH A;  4H30 A;  1HY7 A;  4H3X A;  2W0D A;  1I73 A;  4JPA A;  2O36 A;  1ND1 A;  2ERQ A;  4PKU A;  1K7I A;  1AYK A;  3O64 A;  2DW1 A;  1OMJ A;  2WO9 A;  4G9L A;  1OM6 A;  3I7I A;  4EFS A;  2W15 A;  3EDZ A;  2DDF A;  1IAE A;  2JIH A;  4GUY A;  1QIB A;  3F16 A;  1A86 A;  2JT5 A;  4GR0 A;  1G12 A;  1XM5 A;  3OHL A;  1B8Y A;  2X3B A;  1XFX A;  1JKY A;  1KAP P;  3DTE A;  3EDI A;  3P1V A;  4AXQ A;  1OM8 A;  3F18 A;  1TVI A;  3DPE A;  3HBU P;  4A3W A;  4WZV A;  3RTT A;  1D8F A;  4DD8 A;  1IAD A;  2CKI A;  4PKT A;  2XS4 A;  3EHX A;  1GKD A;  3ELM A;  1B3D A;  1D5J A;  1HFC A;  4WF6 A;  2A8H A;  2OXW A;  1XUC A;  4FXY P;  3TS4 A;  2RJP A;  3KHI A;  2W14 A;  3DTI A;  830C A;  4XM8 A;  3F15 A;  3EWJ A;  1Y8J A;  3B2Z A;  3AIG A;  2OY4 A;  2AYK A;  3G42 A;  3G5C A;  1FBL A;  1HV5 A;  4H76 A;  5D1S A;  2J0T A;  1CIZ A;  1GKC A;  3LKA A;  3LEA A;  5JMY A;  3ZVS A;  1OO9 A;  1YCM A;  2AIG P;  1C3I A;  1QIA A;  1ZVX A;  5D3C A;  1JAQ A;  1G05 A;  1SU3 A;  2JSD A;  2KRJ A;  3LQ0 A;  4CTH A;  3HB2 P;  1A85 A;  1MMP A;  3EHY A;  1D7X A;  3HBV P;  1IAA A;  4JA1 A;  5I3M A;  1MMQ A;  1R55 A;  3AYU A;  1CGF A;  4Q1L A;  1O0T A;  2I47 A;  3KWV C;  3UVC A;  2XS3 A;  1CGE A;  5D7W A;  1YOU A;  1Q3A A;  3KEC A;  1GXD A;  2E3X A;  1EUB A;  1OS9 A;  3LGP A;  4IUW A;  4XM7 A;  3I7G A;  1MMR A;  1RMZ A;  3DNG A;  1Z3J A;  3LJZ A;  2JNP A;  2D1N A;  1KUI A;  5B5O A;  4IN9 A;  1CGL A;  3EDG A;  5D1U A;  1JH1 A;  1IAG A;  1R1J A;  4JIJ A;  2X7M A;  3Q2H A;  4A7B A;  1XFU A;  1I76 A;  4PKV A;  1DTH A;  966C A;  1K7G A;  1ATL A;  5D2B A;  1C8T A;  3L0T A;  456C A;  3DL1 A;  1CK7 A;  2MLS A;  5B5P A;  4L7A A;  1KUG A;  1Y0V A;  1YQY A;  1JK3 A;  3WV1 A;  1SLN A;  3OHO A;  1XUD A;  4L6T A;  2MLR A;  3WV3 A;  1BIW A;  2OW2 A;  2OW0 A;  4WKE A;  3MA2 A;  4XCT A;  4GWM A;  1JJ9 A;  5I0L A;  1AST A;  2Z2D A;  3TVC A;  2OVX A;  3N2V A;  2MZI A;  3LUM A;  1XUR A;  3BA0 A;  3VI1 A;  4H2E A;  1SMP A;  1XAX A;  3VTG A;  4FXQ A;  2K9C A;  5L79 A;  5BPA A;  4FU4 A;  1ZXV A;  1BQO A;  5I43 A;  3EDH A;  4PKR A;  1BZS A;  3LUN A;  1G49 A;  1R1I A;  4QKZ A;  3RTS A;  1QIC A;  1XFY A;  2K2G A;  4AUO A;  4HMA A;  2MZE A;  1IAB A;  3F17 A;  3LIL A;  2J83 A;  3DSL A;  1ZP5 A;  1JAN A;  2QPJ A;  2SRT A;  1HTD A;  1PWW A;  3HY9 A;  3KEJ A;  4ZR5 A;  3KEK A;  4GWN A;  1MMB A;  2DDY A;  2FV9 A;  3AYK A;  1XFW A;  2WO8 A;  4JQG A;  1PWQ A;  2ERO A;  1UMT A;  1OM7 A;  1AF0 A;  1IAC A;  2CLT A;  1PWV A;  1GE6 A;  1MNC A;  2YIG A;  2O3E A;  2V4B A;  5I12 A;  3N2U A;  4I35 A;  4AIG A;  1DMT A;  1ZTQ A;  3KME A;  1R54 A;  2OW1 A;  3LQB A;  4JP4 A;  3LIR A;  2W13 A;  2YUF A;  1PWU A;  3Q2G A;  4AYK A;  3NX7 A;  1SRP A;  4ILW D;  1GE5 A;  1BUD A;  1GO8 P;  1ROS A;  1G4K A;  1D8M A;  1BQQ M;  3F1A A;  2OZR A;  3KMC A;  3K7N A;  1SAT A;  1KUK A;  1L6J A;  4FVL A;  3K7L A;  4HX3 A;  1PWP A;  1FLS A;  3O2X A;  4XM6 A;  1OS2 A;  1HOV A;  2N8R A;  1O0Q A;  5BOT A;  2OW9 A;  1QUA A;  2JT6 A;  1JIZ A;  4PKW A;  3HDB A;  2USN A;  3SHI A;  2MZH A;  2E2D A;  2HU6 A;  1HFS A;  3DTK A;  4H49 A;  4H82 A;  3GBO A;  4ON1 A;  1JAP A;  2FV5 A;  3LJT A;  1XFV A;  5CXA A;  2WOA A;  4GR8 A;  3LJG A;  2D1O A;  4GQL A;  1XFZ A;  4PKS A;  2DW0 A;  2YB9 A;  3P24 A;  5D1T A;  2DW2 A;  1ZS0 A;  3LIK A;  3F19 A;  2OY2 A;  1QJJ A;  5L7F A;  3USN A;  3ZXH A;  3HYG A;  1BKC E;  3WV2 A;  4WKI A;  5CUH A;  1GO7 P;  3ZUK A;  3KRY A;  2TCL A;  1UTZ A;  1C7K A;  1G9K A;  2L0R A;  1CAQ A;  5I4O A;  1UEA A;  1CQR A;  4DV8 A;  1K7Q A;  4DPE A;  1S4B P;  4IJO A;  3TT4 A;  3LMC A;  4H84 A;  1BUV M;  1USN A;  1KBC A;  2RJQ A;  2ERP A;  3HY7 A;  1UMS A;  1AKL A;  2OI0 A;  2OXU A;  1H71 P;  2OVZ A;  2W12 A;  2PJT A;  1UTT A;  5H8X A;  5LAB A;  2X3C A;  3CKI A;  3U1R A;  2Y6D A;  1Y93 A;  1YP1 A;  4GF1 A;  5I2Z A;  3V96 B;  2POJ A;  4J4M A;  4PKQ A;  5BOY A;  4DF9 A;  4H1Q A;  1JIW P;  1J7N A;  1KUF A;  2Y6C A;  1JAO A;  1BKC A;  1WNI A;  4XBH A;  1FM1 A;  4G0D A;  1CXV A;  1SLM A;  1EAK A;  1GE7 A;  4L19 A;  4WK7 A;  1BM6 A;  3B8Z A;  1BKC I;  4GR3 A;  4I03 A;  1BSW A;  3DWB A;  3LE9 A;  1QJI A;  4R3V A;  3TSK A;  1RM8 A;  5CZM A;  2X3A A;  3E8R A; 
#chains in the Genus database with same CATH homology
 1R1H A;  1EB6 A;  4L63 A;  3DPF A;  1ZXC A;  3LK8 A;  1I1I P;  2OXZ A;  3HDA P;  3L0V A;  3B92 A;  1KUH A;  4H30 A;  1HY7 A;  4H3X A;  2W0D A;  1I73 A;  4JPA A;  2O36 A;  1ND1 A;  2ERQ A;  4PKU A;  1K7I A;  1AYK A;  3O64 A;  2DW1 A;  1OMJ A;  2WO9 A;  4G9L A;  1OM6 A;  3I7I A;  4EFS A;  2W15 A;  3EDZ A;  2DDF A;  1IAE A;  2JIH A;  4GUY A;  1QIB A;  3F16 A;  1A86 A;  2JT5 A;  4GR0 A;  1G12 A;  3OHL A;  1B8Y A;  2X3B A;  1XFX A;  1JKY A;  1KAP P;  3DTE A;  3EDI A;  3P1V A;  4AXQ A;  1OM8 A;  3F18 A;  3HBU P;  3DPE A;  4A3W A;  4WZV A;  3RTT A;  1D8F A;  4DD8 A;  1IAD A;  2CKI A;  4PKT A;  2XS4 A;  3EHX A;  1GKD A;  3ELM A;  1B3D A;  1D5J A;  1HFC A;  4WF6 A;  2A8H A;  2OXW A;  1XUC A;  4FXY P;  3TS4 A;  2RJP A;  3KHI A;  2W14 A;  3DTI A;  830C A;  4XM8 A;  3F15 A;  3EWJ A;  1Y8J A;  3B2Z A;  3AIG A;  2OY4 A;  2AYK A;  3G42 A;  3G5C A;  1FBL A;  1HV5 A;  4H76 A;  5D1S A;  2J0T A;  1CIZ A;  1GKC A;  3LKA A;  3LEA A;  5JMY A;  3ZVS A;  1OO9 A;  1YCM A;  2AIG P;  1C3I A;  1QIA A;  1ZVX A;  5D3C A;  1JAQ A;  1G05 A;  1SU3 A;  2JSD A;  2KRJ A;  3LQ0 A;  4CTH A;  3HB2 P;  1A85 A;  1MMP A;  3EHY A;  1D7X A;  3HBV P;  1IAA A;  4JA1 A;  5I3M A;  1MMQ A;  1R55 A;  3AYU A;  1CGF A;  4Q1L A;  1O0T A;  2I47 A;  3KWV C;  3UVC A;  2XS3 A;  1CGE A;  5D7W A;  1YOU A;  1Q3A A;  3KEC A;  1GXD A;  2E3X A;  1EUB A;  1OS9 A;  3LGP A;  4IUW A;  4XM7 A;  3I7G A;  1MMR A;  1RMZ A;  3DNG A;  1Z3J A;  3LJZ A;  2JNP A;  2D1N A;  1KUI A;  5B5O A;  4IN9 A;  1CGL A;  3EDG A;  5D1U A;  1JH1 A;  1IAG A;  1R1J A;  4JIJ A;  2X7M A;  3Q2H A;  4A7B A;  1XFU A;  1I76 A;  4PKV A;  1DTH A;  966C A;  1K7G A;  1ATL A;  5D2B A;  1C8T A;  3L0T A;  456C A;  3DL1 A;  1CK7 A;  2MLS A;  5B5P A;  4L7A A;  1KUG A;  1Y0V A;  1YQY A;  1JK3 A;  3WV1 A;  1SLN A;  3OHO A;  1XUD A;  4L6T A;  2MLR A;  3WV3 A;  1BIW A;  2OW2 A;  2OW0 A;  4WKE A;  3MA2 A;  4XCT A;  4GWM A;  1JJ9 A;  5I0L A;  1AST A;  2Z2D A;  3TVC A;  2OVX A;  3N2V A;  2MZI A;  3LUM A;  1XUR A;  3BA0 A;  3VI1 A;  4H2E A;  1SMP A;  3VTG A;  4FXQ A;  2K9C A;  5L79 A;  5BPA A;  4FU4 A;  1ZXV A;  1BQO A;  5I43 A;  3EDH A;  4PKR A;  1BZS A;  3LUN A;  1G49 A;  1R1I A;  4QKZ A;  3RTS A;  1QIC A;  1XFY A;  2K2G A;  4AUO A;  4HMA A;  2MZE A;  1IAB A;  3F17 A;  3LIL A;  2J83 A;  3DSL A;  1ZP5 A;  1JAN A;  2QPJ A;  2SRT A;  1HTD A;  1PWW A;  3HY9 A;  3KEJ A;  4ZR5 A;  3KEK A;  4GWN A;  1MMB A;  2DDY A;  2FV9 A;  3AYK A;  1XFW A;  2WO8 A;  4JQG A;  1PWQ A;  2ERO A;  1UMT A;  1OM7 A;  1AF0 A;  1IAC A;  2CLT A;  1PWV A;  1GE6 A;  1MNC A;  2YIG A;  2O3E A;  2V4B A;  5I12 A;  3N2U A;  4I35 A;  4AIG A;  1DMT A;  1ZTQ A;  3KME A;  1R54 A;  2OW1 A;  3LQB A;  4JP4 A;  3LIR A;  2W13 A;  2YUF A;  1PWU A;  3Q2G A;  4AYK A;  3NX7 A;  1SRP A;  4ILW D;  1GE5 A;  1BUD A;  1GO8 P;  1ROS A;  1G4K A;  1D8M A;  1BQQ M;  3F1A A;  2OZR A;  3KMC A;  3K7N A;  1SAT A;  1KUK A;  1L6J A;  4FVL A;  3K7L A;  4HX3 A;  1PWP A;  1FLS A;  3O2X A;  4XM6 A;  1OS2 A;  1HOV A;  2N8R A;  1O0Q A;  5BOT A;  2OW9 A;  1QUA A;  2JT6 A;  1JIZ A;  4PKW A;  3HDB A;  2USN A;  3SHI A;  2MZH A;  2E2D A;  2HU6 A;  1HFS A;  3DTK A;  4H49 A;  4H82 A;  3GBO A;  4ON1 A;  1JAP A;  2FV5 A;  3LJT A;  1XFV A;  5CXA A;  2WOA A;  4GR8 A;  3LJG A;  2D1O A;  4GQL A;  1XFZ A;  4PKS A;  2DW0 A;  2YB9 A;  3P24 A;  5D1T A;  2DW2 A;  1ZS0 A;  3LIK A;  3F19 A;  2OY2 A;  1QJJ A;  5L7F A;  3USN A;  3ZXH A;  3HYG A;  1BKC E;  3WV2 A;  4WKI A;  5CUH A;  1GO7 P;  3ZUK A;  3KRY A;  2TCL A;  1UTZ A;  1C7K A;  1G9K A;  2L0R A;  1CAQ A;  5I4O A;  1UEA A;  1CQR A;  4DV8 A;  1K7Q A;  4DPE A;  1S4B P;  4IJO A;  3TT4 A;  3LMC A;  4H84 A;  1BUV M;  1USN A;  1KBC A;  2RJQ A;  2ERP A;  3HY7 A;  1UMS A;  1AKL A;  2OI0 A;  2OXU A;  1H71 P;  2OVZ A;  2W12 A;  2PJT A;  1UTT A;  5H8X A;  5LAB A;  2X3C A;  3CKI A;  3U1R A;  2Y6D A;  1Y93 A;  1YP1 A;  4GF1 A;  5I2Z A;  3V96 B;  2POJ A;  4J4M A;  4PKQ A;  5BOY A;  4DF9 A;  4H1Q A;  1JIW P;  1J7N A;  1KUF A;  2Y6C A;  1JAO A;  1BKC A;  1WNI A;  4XBH A;  1FM1 A;  4G0D A;  1CXV A;  1SLM A;  1EAK A;  1GE7 A;  4L19 A;  4WK7 A;  1BM6 A;  3B8Z A;  1BKC I;  4GR3 A;  4I03 A;  1BSW A;  3DWB A;  3LE9 A;  1QJI A;  4R3V A;  3TSK A;  1RM8 A;  5CZM A;  2X3A A;  3E8R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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