1IZNA

Crystal structure of actin filament capping protein capz
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
275
structure length
275
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of CapZ: structural basis for actin filament barbed end capping
pubmed doi rcsb
molecule tags Protein binding
source organism Gallus gallus
molecule keywords CapZ alpha-1 subunit
total genus 72
structure length 275
sequence length 275
chains with identical sequence C
ec nomenclature
pdb deposition date 2002-10-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 1iznA01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 1iznA02
2KXPA 3AA1B 3AA7A 3AAAB 3AA0B 2KXPB 1IZNB 3LK2A 3AAEA 3AA7B 5AFUK 5AFUL 4AKRA 3AA6A 3AA0A 3LK42 3LK2B 3AAEB 2KZ7A 4AKRB 3AA6B 3LK3A 3LK41 5ADXK 5ADXL 2KZ7B 3AAAA 3AA1A 1IZNA 3LK3B
chains in the Genus database with same CATH superfamily
5GTHO 1QJPA 3A0HO 2R4NA 5IYUA 3AA7A 2X9KA 3LK2A 5D5DA 2IWWA 2ES9A 1GU9A 4G75A 2ODJA 2WVPA 4RJWA 3SZVA 1THQA 1E54A 1GFNA 4JCHA 1QJ9A 3SZDA 3O0EA 1ZHWA 5JDPA 2QEUA 2IJCA 2Y0HA 2R4PA 4GHBA 5FVNA 1G90A 2KZ7B 3BS0A 2WJRA 4LSFA 4AYID 5B5EO 1OSMA 2ZFGA 1H6S1 3T0SA 5PRNA 3A0BO 2W80C 5DL7A 2R8AA 4E1SA 4AZLA 4FSPA 5DL5A 3KVDD 3QRCA 1BT9A 2KZ7A 4FMSA 2KC0A 2Y0KA 1MM5A 1YS5A 2M06A 4KR4A 1ZHTA 3LK3B 3WU2O 3BEYA 3NSGA 3UPGA 4RLCA 4GCQA 4B61A 2MNHA 4O3WA 4AKMA 4O3XB 2AXTO 4GF4A 2Q0TA 1GFPA 4KRAA 3LK3A 3GP6A 4AYMC 3QRAA 3PGUA 3SYBA 4FZMA 1HXTA 1QJ8A 3AA1B 2Y2XA 3HWBA 3SY7A 2O4DA 2J4UP 2R89A 4N59A 3LK2B 2Y0LA 2JQYA 2YNKA 4LSHA 3AA1A 1P8CA 4N58A 5H2FO 4N74A 5G38A 4FOZA 2F1CX 2PORA 3C5OA 4K3BA 4PUXA 3DZMA 3NJTA 3JTYA 4XNKA 3HOEA 5G39A 4GCSA 4AYEC 3EMNX 2GMYA 8PRNA 5EE2A 2IWVA 5T5FA 3RBHA 1ZHXA 2XE3A 2JMMA 7PRNA 5DIPA 4G9QA 4FUVA 5TISO 2Y7SA 2R4LA 3VY8X 1IZNA 2K4TA 4UB6O 4K3CA 4O3YA 4CTDA 4RLBA 3UU2A 2KXPB 5DL6A 1PRNA 4PJ0O 4F4BA 5DIKA 3KZIO 3UAQA 3WI5A 5G26A 4FRXA 3PF1A 2XTRA 3LK41 1KNCA 4N75A 5ADXL 2KXPA 2GE4A 1PHOA 2OMFA 2F1TA 3VE2A 4FRTA 2ERVA 1ORMA 1ZHZA 1T16A 2LFUA 4O49A 4Z3TA 3POQA 4FSOA 1Q9FA 1BXWA 4RJXA 3SYSA 5AFUL 3V8UA 3VE1A 3LK42 4XNLA 1BH3A 3DA3A 4GCPA 5ADXK 1T1LA 1MPFA 3A2SX 4C4VA 5DL8A 3T20A 3PQUA 1HXUA 2CWQA 4U9CA 2XE5A 2R88A 4D65A 3PGRA 2JN8A 1VKEA 4AKRB 4QQ1A 4JFBA 4AFKA 3WI4A 2XMXA 3POXA 3AAAA 3AA0A 5B66O 1GFMA 3POUA 1LW1A 2XG6A 2M07A 3JCUO 4FZNA 4AKRA 4FZLA 5E79O 5G3AA 1ZHYA 3AA6B 3DA4A 1GFQA 3G7GA 3PQSA 1IZNB 3FYXA 4FESA 3AAEA 3AA6A 4IL6O 4FQEA 2YPVA 4D64A 3PRNA 2XE2A 3HOLA 4E1TA 2O4VA 4KR8A 3SY9A 2LHFA 2J1NA 3PORA 3BRZA 4C69X 2OYOA 2W81C 4LSEA 2X27X 1Q9GA 3K19A 3C1LA 3D7IA 1MM4A 2N2MA 2XE1A 2WJQA 2ZLDA 3LVYA 3TZGA 2OUWA 4O4XA 4G76A 4UB8O 1S5LO 3T24A 2FGRA 4D5UA 5KAFO 4C4VB 4RL9A 2F1VA 3VY9X 3VZTX 5GTIO 4AUIA 3VZWX 4O4UA 4C00A 3DWOX 2FGQX 3AAAB 3AA0B 2MHLA 1OPFA 3BRYA 2KDYA 2AF7A 3HW9A 5AFUK 1P4TA 2PRNA 2PFXA 4FT6A 4AYDC 3DWNA 6PRNA 4BUMX 5KAIO 1GFOA 2PRRA 4LSIA 2K0LA 3PGSA 1HXXA 3VZUX 2R4OA 2N2LA 3AA7B 2XTQA 5GV0A 1ME5A 3AAEB 4AYNA 4O3ZA 4PR7A 2QTKA
chains in the Genus database with same CATH topology
3SYBA 1QJPA 3SY9A 2KXPA 2J1NA 2GE4A 2LHFA 3PORA 4FZMA 1PHOA 2OMFA 1HXTA 2F1TA 4C69X 2OYOA 1QJ8A 3AA1B 4FRTA 2ERVA 2Y2XA 3AA7A 3VE2A 5IYUA 2W81C 1ORMA 1ZHZA 4LSEA 2X27X 3HWBA 3LK2A 1Q9GA 3C1LA 2LFUA 3K19A 4O49A 5D5DA 4Z3TA 3SY7A 3D7IA 2O4DA 1Q9FA 2ES9A 1BXWA 3POQA 4FSOA 4RJXA 3SYSA 5AFUL 3V8UA 1MM4A 3VE1A 1GU9A 2J4UP 2N2MA 4G75A 2ODJA 3LK42 4N59A 3LK2B 4XNLA 1BH3A 3DA3A 2Y0LA 2XE1A 2YNKA 4RJWA 4GCPA 3SZVA 4LSHA 5ADXK 2ZLDA 3LVYA 3TZGA 2OUWA 1THQA 1E54A 3AA1A 1P8CA 4N58A 1GFNA 4O4XA 1MPFA 4JCHA 3A2SX 4G76A 1QJ9A 4FOZA 3SZDA 3O0EA 2PORA 5DL8A 3C5OA 1ZHWA 3T20A 5JDPA 2QEUA 3PQUA 3T24A 1HXUA 4PUXA 2FGRA 2IJCA 4D5UA 2CWQA 2Y0HA 4GHBA 4RL9A 4U9CA 2F1VA 2XE5A 3JTYA 5FVNA 4D65A 2JN8A 1G90A 4XNKA 1VKEA 3VY9X 4AKRB 4QQ1A 4JFBA 3VZTX 4AFKA 3HOEA 4GCSA 3WI4A 2XMXA 4AYEC 3EMNX 2GMYA 3POXA 8PRNA 2KZ7B 3AAAA 3AA0A 5EE2A 5T5FA 4AUIA 1GFMA 1ZHXA 3POUA 3RBHA 2XE3A 3VZWX 1LW1A 4LSFA 4O4UA 4AYID 2XG6A 1OSMA 2FGQX 3AAAB 2ZFGA 3AA0B 1H6S1 2MHLA 1OPFA 2JMMA 7PRNA 3T0SA 5DIPA 2KDYA 5PRNA 2M07A 2AF7A 3HW9A 5AFUK 1P4TA 2PRNA 4FZNA 2W80C 4AKRA 4FZLA 4G9QA 5DL7A 4AZLA 4FSPA 4E1SA 5DL5A 3KVDD 3QRCA 1BT9A 1ZHYA 2KZ7A 4FMSA 3AA6B 4FUVA 2KC0A 2PFXA 2Y0KA 4FT6A 2Y7SA 1MM5A 3DA4A 3VY8X 4AYDC 6PRNA 1YS5A 2M06A 1IZNA 1ZHTA 2K4TA 3LK3B 4KR4A 3BEYA 3NSGA 3UPGA 4BUMX 1GFOA 1GFQA 4RLCA 4O3YA 3G7GA 4GCQA 3PQSA 4B61A 4RLBA 3UU2A 2KXPB 1IZNB 2PRRA 5DL6A 1PRNA 2MNHA 4LSIA 2K0LA 3VZUX 1HXXA 4O3WA 4AKMA 3FYXA 4FESA 3AAEA 2N2LA 3AA7B 4O3XB 2XTQA 4GF4A 5GV0A 1ME5A 3AA6A 4F4BA 5DIKA 2YPVA 4D64A 3PRNA 2Q0TA 2XE2A 3AAEB 3UAQA 3WI5A 3HOLA 4AYNA 4E1TA 5G26A 1GFPA 4FRXA 2XTRA 4KRAA 3LK3A 3LK41 3GP6A 1KNCA 4O3ZA 2O4VA 2QTKA 4KR8A 5ADXL 4AYMC 3QRAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KXP A;  3AA1 B;  3AA7 A;  3AAA B;  3AA0 B;  2KXP B;  1IZN B;  3LK2 A;  3AAE A;  3AA7 B;  5AFU K;  5AFU L;  4AKR A;  3AA6 A;  3AA0 A;  3LK4 2;  3LK2 B;  3AAE B;  2KZ7 A;  4AKR B;  3AA6 B;  3LK3 A;  3LK4 1;  5ADX K;  5ADX L;  2KZ7 B;  3AAA A;  3AA1 A;  1IZN A;  3LK3 B; 
#chains in the Genus database with same CATH topology
 5GTH O;  1QJP A;  3A0H O;  2R4N A;  5IYU A;  3AA7 A;  2X9K A;  3LK2 A;  5D5D A;  2IWW A;  2ES9 A;  1GU9 A;  4G75 A;  2ODJ A;  2WVP A;  4RJW A;  3SZV A;  1THQ A;  1E54 A;  1GFN A;  4JCH A;  1QJ9 A;  3SZD A;  3O0E A;  1ZHW A;  5JDP A;  2QEU A;  2IJC A;  2Y0H A;  2R4P A;  4GHB A;  5FVN A;  1G90 A;  2KZ7 B;  3BS0 A;  2WJR A;  4LSF A;  4AYI D;  5B5E O;  1OSM A;  2ZFG A;  1H6S 1;  3T0S A;  5PRN A;  3A0B O;  2W80 C;  5DL7 A;  2R8A A;  4E1S A;  4AZL A;  4FSP A;  5DL5 A;  3KVD D;  3QRC A;  1BT9 A;  2KZ7 A;  4FMS A;  2KC0 A;  2Y0K A;  1MM5 A;  1YS5 A;  2M06 A;  4KR4 A;  1ZHT A;  3LK3 B;  3WU2 O;  3BEY A;  3NSG A;  3UPG A;  4RLC A;  4GCQ A;  4B61 A;  2MNH A;  4O3W A;  4AKM A;  4O3X B;  2AXT O;  4GF4 A;  2Q0T A;  1GFP A;  4KRA A;  3LK3 A;  3GP6 A;  4AYM C;  3QRA A;  3PGU A;  3SYB A;  4FZM A;  1HXT A;  1QJ8 A;  3AA1 B;  2Y2X A;  3HWB A;  3SY7 A;  2O4D A;  2J4U P;  2R89 A;  4N59 A;  3LK2 B;  2Y0L A;  2JQY A;  2YNK A;  4LSH A;  3AA1 A;  1P8C A;  4N58 A;  5H2F O;  4N74 A;  5G38 A;  4FOZ A;  2F1C X;  2POR A;  3C5O A;  4K3B A;  4PUX A;  3DZM A;  3NJT A;  3JTY A;  4XNK A;  3HOE A;  5G39 A;  4GCS A;  4AYE C;  3EMN X;  2GMY A;  8PRN A;  5EE2 A;  2IWV A;  5T5F A;  3RBH A;  1ZHX A;  2XE3 A;  2JMM A;  7PRN A;  5DIP A;  4G9Q A;  4FUV A;  5TIS O;  2Y7S A;  2R4L A;  3VY8 X;  1IZN A;  2K4T A;  4UB6 O;  4K3C A;  4O3Y A;  4CTD A;  4RLB A;  3UU2 A;  2KXP B;  5DL6 A;  1PRN A;  4PJ0 O;  4F4B A;  5DIK A;  3KZI O;  3UAQ A;  3WI5 A;  5G26 A;  4FRX A;  3PF1 A;  2XTR A;  3LK4 1;  1KNC A;  4N75 A;  5ADX L;  2KXP A;  2GE4 A;  1PHO A;  2OMF A;  2F1T A;  3VE2 A;  4FRT A;  2ERV A;  1ORM A;  1ZHZ A;  1T16 A;  2LFU A;  4O49 A;  4Z3T A;  3POQ A;  4FSO A;  1Q9F A;  1BXW A;  4RJX A;  3SYS A;  5AFU L;  3V8U A;  3VE1 A;  3LK4 2;  4XNL A;  1BH3 A;  3DA3 A;  4GCP A;  5ADX K;  1T1L A;  1MPF A;  3A2S X;  4C4V A;  5DL8 A;  3T20 A;  3PQU A;  1HXU A;  2CWQ A;  4U9C A;  2XE5 A;  2R88 A;  4D65 A;  3PGR A;  2JN8 A;  1VKE A;  4AKR B;  4QQ1 A;  4JFB A;  4AFK A;  3WI4 A;  2XMX A;  3POX A;  3AAA A;  3AA0 A;  5B66 O;  1GFM A;  3POU A;  1LW1 A;  2XG6 A;  2M07 A;  3JCU O;  4FZN A;  4AKR A;  4FZL A;  5E79 O;  5G3A A;  1ZHY A;  3AA6 B;  3DA4 A;  1GFQ A;  3G7G A;  3PQS A;  1IZN B;  3FYX A;  4FES A;  3AAE A;  3AA6 A;  4IL6 O;  4FQE A;  2YPV A;  4D64 A;  3PRN A;  2XE2 A;  3HOL A;  4E1T A;  2O4V A;  4KR8 A;  3SY9 A;  2LHF A;  2J1N A;  3POR A;  3BRZ A;  4C69 X;  2OYO A;  2W81 C;  4LSE A;  2X27 X;  1Q9G A;  3K19 A;  3C1L A;  3D7I A;  1MM4 A;  2N2M A;  2XE1 A;  2WJQ A;  2ZLD A;  3LVY A;  3TZG A;  2OUW A;  4O4X A;  4G76 A;  4UB8 O;  1S5L O;  3T24 A;  2FGR A;  4D5U A;  5KAF O;  4C4V B;  4RL9 A;  2F1V A;  3VY9 X;  3VZT X;  5GTI O;  4AUI A;  3VZW X;  4O4U A;  4C00 A;  3DWO X;  2FGQ X;  3AAA B;  3AA0 B;  2MHL A;  1OPF A;  3BRY A;  2KDY A;  2AF7 A;  3HW9 A;  5AFU K;  1P4T A;  2PRN A;  2PFX A;  4FT6 A;  4AYD C;  3DWN A;  6PRN A;  4BUM X;  5KAI O;  1GFO A;  2PRR A;  4LSI A;  2K0L A;  3PGS A;  1HXX A;  3VZU X;  2R4O A;  2N2L A;  3AA7 B;  2XTQ A;  5GV0 A;  1ME5 A;  3AAE B;  4AYN A;  4O3Z A;  4PR7 A;  2QTK A; 
#chains in the Genus database with same CATH homology
 3SYB A;  1QJP A;  3SY9 A;  2KXP A;  2J1N A;  2GE4 A;  2LHF A;  3POR A;  4FZM A;  1PHO A;  2OMF A;  1HXT A;  2F1T A;  4C69 X;  2OYO A;  1QJ8 A;  3AA1 B;  4FRT A;  2ERV A;  2Y2X A;  3AA7 A;  3VE2 A;  5IYU A;  2W81 C;  1ORM A;  1ZHZ A;  4LSE A;  2X27 X;  3HWB A;  3LK2 A;  1Q9G A;  3C1L A;  2LFU A;  3K19 A;  4O49 A;  5D5D A;  4Z3T A;  3SY7 A;  3D7I A;  2O4D A;  1Q9F A;  2ES9 A;  1BXW A;  3POQ A;  4FSO A;  4RJX A;  3SYS A;  5AFU L;  3V8U A;  1MM4 A;  3VE1 A;  1GU9 A;  2J4U P;  2N2M A;  4G75 A;  2ODJ A;  3LK4 2;  4N59 A;  3LK2 B;  4XNL A;  1BH3 A;  3DA3 A;  2Y0L A;  2XE1 A;  2YNK A;  4RJW A;  4GCP A;  3SZV A;  4LSH A;  5ADX K;  2ZLD A;  3LVY A;  3TZG A;  2OUW A;  1THQ A;  1E54 A;  3AA1 A;  1P8C A;  4N58 A;  1GFN A;  4O4X A;  1MPF A;  4JCH A;  3A2S X;  4G76 A;  1QJ9 A;  4FOZ A;  3SZD A;  3O0E A;  2POR A;  5DL8 A;  3C5O A;  1ZHW A;  3T20 A;  5JDP A;  2QEU A;  3PQU A;  3T24 A;  1HXU A;  4PUX A;  2FGR A;  2IJC A;  4D5U A;  2CWQ A;  2Y0H A;  4GHB A;  4RL9 A;  4U9C A;  2F1V A;  2XE5 A;  3JTY A;  5FVN A;  4D65 A;  2JN8 A;  1G90 A;  4XNK A;  1VKE A;  3VY9 X;  4AKR B;  4QQ1 A;  4JFB A;  3VZT X;  4AFK A;  3HOE A;  4GCS A;  3WI4 A;  2XMX A;  4AYE C;  3EMN X;  2GMY A;  3POX A;  8PRN A;  2KZ7 B;  3AAA A;  3AA0 A;  5EE2 A;  5T5F A;  4AUI A;  1GFM A;  1ZHX A;  3POU A;  3RBH A;  2XE3 A;  3VZW X;  1LW1 A;  4LSF A;  4O4U A;  4AYI D;  2XG6 A;  1OSM A;  2FGQ X;  3AAA B;  2ZFG A;  3AA0 B;  1H6S 1;  2MHL A;  1OPF A;  2JMM A;  7PRN A;  3T0S A;  5DIP A;  2KDY A;  5PRN A;  2M07 A;  2AF7 A;  3HW9 A;  5AFU K;  1P4T A;  2PRN A;  4FZN A;  2W80 C;  4AKR A;  4FZL A;  4G9Q A;  5DL7 A;  4AZL A;  4FSP A;  4E1S A;  5DL5 A;  3KVD D;  3QRC A;  1BT9 A;  1ZHY A;  2KZ7 A;  4FMS A;  3AA6 B;  4FUV A;  2KC0 A;  2PFX A;  2Y0K A;  4FT6 A;  2Y7S A;  1MM5 A;  3DA4 A;  3VY8 X;  4AYD C;  6PRN A;  1YS5 A;  2M06 A;  1IZN A;  1ZHT A;  2K4T A;  3LK3 B;  4KR4 A;  3BEY A;  3NSG A;  3UPG A;  4BUM X;  1GFO A;  1GFQ A;  4RLC A;  4O3Y A;  3G7G A;  4GCQ A;  3PQS A;  4B61 A;  4RLB A;  3UU2 A;  2KXP B;  1IZN B;  2PRR A;  5DL6 A;  1PRN A;  2MNH A;  4LSI A;  2K0L A;  3VZU X;  1HXX A;  4O3W A;  4AKM A;  3FYX A;  4FES A;  3AAE A;  2N2L A;  3AA7 B;  4O3X B;  2XTQ A;  4GF4 A;  5GV0 A;  1ME5 A;  3AA6 A;  4F4B A;  5DIK A;  2YPV A;  4D64 A;  3PRN A;  2Q0T A;  2XE2 A;  3AAE B;  3UAQ A;  3WI5 A;  3HOL A;  4AYN A;  4E1T A;  5G26 A;  1GFP A;  4FRX A;  2XTR A;  4KRA A;  3LK3 A;  3LK4 1;  3GP6 A;  1KNC A;  4O3Z A;  2O4V A;  2QTK A;  4KR8 A;  5ADX L;  4AYM C;  3QRA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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