1IZNA

Crystal structure of actin filament capping protein capz
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
275
structure length
275
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of CapZ: structural basis for actin filament barbed end capping
pubmed doi rcsb
molecule tags Protein binding
source organism Gallus gallus
molecule keywords CapZ alpha-1 subunit
total genus 72
structure length 275
sequence length 275
chains with identical sequence C
ec nomenclature
pdb deposition date 2002-10-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 1iznA01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 1iznA02
3AAEB 3AA1B 1IZNA 3AAEA 3AA1A 2KXPB 2KZ7B 2KXPA 2KZ7A 5AFUK 3AA6B 3AAAB 3AA6A 5AFUL 3AAAA 5ADXK 3LK3B 4AKRB 3LK3A 4AKRA 3LK41 5ADXL 3AA7B 3AA7A 3LK2B 3LK42 3LK2A 3AA0B 3AA0A 1IZNB
chains in the Genus database with same CATH superfamily
2ODJA 2R4OA 2K4TA 3AA1B 2GMYA 4GCSA 4O4UA 2R4NA 1BH3A 3EMNX 3G7GA 2KC0A 5ADXK 3VZWX 2AF7A 4FRTA 3AA7B 4PUXA 4AYMC 3POUA 2W80C 1GFNA 4U9CA 1IZNA 5KAIO 2M07A 1OPFA 2JQYA 2KXPB 5DIKA 2PORA 2ZLDA 4AFKA 4LSEA 1HXTA 5ADXL 2ZFGA 1PHOA 5B5EO 3T24A 2X9KA 4IL6O 4UB8O 1QJ9A 3BS0A 3PQSA 4PR7A 3SYSA 4KR4A 5G3AA 2OUWA 4C00A 5IYUA 3WI5A 4JFBA 7PRNA 2MNHA 3GP6A 1MM5A 1GU9A 4KR8A 2XG6A 3PRNA 5TISO 4AZLA 5GTHO 3AAEB 2XMXA 3SZDA 1MM4A 4O3WA 4O3YA 3KVDD 2M06A 4N58A 2XE2A 4O4XA 1OSMA 3NJTA 3AA0B 1LW1A 4N59A 3JCUO 4AUIA 2KZ7B 4GHBA 4F4BA 3JTYA 5B66O 3RBHA 3D7IA 2FGQX 2R88A 5JDPA 4AKRB 2JN8A 4D5UA 3PGUA 4XNLA 2XE5A 1BT9A 1VKEA 2R8AA 2PFXA 1KNCA 2OMFA 3A0HO 4G9QA 3AA1A 8PRNA 2O4DA 3SY7A 2Y0KA 3DWOX 2JMMA 1Q9FA 4O3ZA 3LK3B 4GF4A 4FSOA 3SZVA 4AYNA 2W81C 3AA7A 2KDYA 4FMSA 1T1LA 5DL8A 2R4PA 1HXUA 5G38A 3NSGA 2ES9A 4RL9A 2KXPA 3PQUA 5T5FA 2F1TA 5EE2A 1T16A 1QJ8A 3BRYA 3HW9A 2O4VA 2R89A 3QRCA 5DL6A 2K0LA 3C1LA 1H6S1 3HOEA 1E54A 3V8UA 3DWNA 2Y0LA 4FSPA 4KRAA 3BEYA 2XTRA 1YS5A 2QTKA 2LFUA 1PRNA 1THQA 2QEUA 3LVYA 1P4TA 2IWWA 2F1CX 5DL7A 2Q0TA 2Y7SA 4GCQA 5D5DA 3AAEA 4K3CA 3SY9A 5AFUK 1BXWA 3AAAB 5KAFO 2PRNA 3TZGA 4FQEA 3VE1A 2WVPA 4RLCA 3DA4A 5GTIO 4E1SA 3T20A 4D64A 2F1VA 4AYEC 3VY9X 3LK2B 2N2LA 3AA0A 4FZLA 4LSIA 3UAQA 1ZHZA 2FGRA 4FESA 2KZ7A 3POXA 5DIPA 4FOZA 5AFUL 3C5OA 4FUVA 1S5LO 4AKRA 3O0EA 4N74A 4G76A 1ZHXA 2YNKA 5PRNA 4C4VB 4XNKA 4K3BA 4BUMX 3VZUX 4O49A 4QQ1A 3AA6B 2J4UP 3PGSA 3WI4A 2PRRA 3LK3A 5G39A 5DL5A 4N75A 4O3XB 3SYBA 2AXTO 3VZTX 2GE4A 1ZHWA 2Y0HA 3UU2A 2WJQA 4AYID 2XE1A 4E1TA 5FVNA 4Z3TA 2IWVA 3A0BO 5E79O 6PRNA 5H2FO 1G90A 1IZNB 4LSFA 3WU2O 4FT6A 3QRAA 3UPGA 1Q9GA 2XTQA 2Y2XA 3LK41 3A2SX 3BRZA 1MPFA 4C69X 3LK42 3VE2A 2XE3A 4RJWA 3FYXA 2R4LA 2X27X 1GFMA 3DZMA 2YPVA 3K19A 4JCHA 4FZNA 4CTDA 3AAAA 4D65A 2N2MA 3PF1A 4FZMA 4B61A 1GFPA 4UB6O 3LK2A 2LHFA 4PJ0O 2OYOA 4RLBA 4FRXA 3KZIO 3PGRA 4RJXA 1ZHTA 1P8CA 5G26A 4AYDC 5GV0A 3HOLA 2J1NA 1ZHYA 4G75A 1GFQA 1HXXA 4C4VA 3T0SA 2ERVA 2MHLA 1QJPA 3AA6A 1ME5A 4GCPA 3PORA 2WJRA 4LSHA 1GFOA 3VY8X 3HWBA 2CWQA 3DA3A 1ORMA 2IJCA 4AKMA 3POQA
chains in the Genus database with same CATH topology
2ODJA 3AA1B 2K4TA 5D5DA 3AAEA 4FT6A 4AUIA 2KZ7B 4GHBA 4F4BA 3QRAA 2GMYA 3SY9A 4GCSA 4O4UA 5AFUK 1BH3A 3EMNX 3G7GA 3JTYA 1BXWA 2KC0A 3AAAB 3D7IA 2FGQX 2PRNA 3RBHA 3UPGA 5JDPA 5ADXK 1Q9GA 3TZGA 3VZWX 2XTQA 4AKRB 2JN8A 2Y2XA 3VE1A 2AF7A 3LK41 3A2SX 3DA4A 4FRTA 4RLCA 3AA7B 4E1SA 4D5UA 3T20A 4D64A 1MPFA 2F1VA 4XNLA 3VY9X 3LK2B 4AYEC 2XE5A 4C69X 3LK42 4PUXA 1BT9A 1VKEA 2N2LA 2XE3A 3AA0A 4RJWA 3FYXA 3VE2A 2PFXA 1KNCA 2OMFA 2X27X 3POUA 4FZLA 4AYMC 4LSIA 2W80C 1GFNA 3UAQA 4U9CA 1ZHZA 1IZNA 2M07A 1OPFA 4G9QA 3AA1A 5DIKA 2KXPB 2PORA 1GFMA 8PRNA 2O4DA 3SY7A 2FGRA 2Y0KA 4FESA 2YPVA 2KZ7A 3K19A 3POXA 4JCHA 5DIPA 2ZLDA 2JMMA 1Q9FA 4O3ZA 4AFKA 4FZNA 4FOZA 5AFUL 3AAAA 4LSEA 3C5OA 4FUVA 3LK3B 4D65A 1HXTA 4GF4A 4AKRA 4FSOA 2ZFGA 5ADXL 3SZVA 2N2MA 3O0EA 4FZMA 2W81C 4AYNA 4B61A 1GFPA 3AA7A 1PHOA 4G76A 2KDYA 3LK2A 2LHFA 1ZHXA 4FMSA 3T24A 2YNKA 5DL8A 5PRNA 1QJ9A 2OYOA 1HXUA 4RLBA 4FRXA 4XNKA 3PQSA 3SYSA 3NSGA 4BUMX 4KR4A 2ES9A 4RL9A 2KXPA 4RJXA 3VZUX 1ZHTA 4O49A 4QQ1A 3AA6B 1P8CA 2OUWA 3PQUA 5G26A 5T5FA 4AYDC 2J4UP 5IYUA 3WI4A 2F1TA 2PRRA 5EE2A 5GV0A 3WI5A 3LK3A 1QJ8A 3HOLA 4JFBA 5DL5A 2J1NA 3HW9A 2O4VA 4O3XB 1ZHYA 3SYBA 7PRNA 2MNHA 3GP6A 1MM5A 1GU9A 4G75A 3VZTX 1GFQA 3QRCA 4KR8A 2XG6A 2GE4A 3PRNA 2K0LA 5DL6A 3C1LA 1H6S1 4AZLA 1HXXA 3HOEA 3AAEB 1E54A 3V8UA 1ZHWA 2XMXA 2Y0HA 3T0SA 2ERVA 2Y0LA 2MHLA 3SZDA 1MM4A 3UU2A 4O3WA 4FSPA 4O3YA 3KVDD 4KRAA 3BEYA 2M06A 4N58A 1QJPA 4AYID 2XTRA 3AA6A 2XE2A 1ME5A 2XE1A 4GCPA 1YS5A 2QTKA 4E1TA 2LFUA 3PORA 4O4XA 1PRNA 1THQA 4LSHA 1GFOA 2QEUA 3VY8X 5FVNA 1OSMA 4Z3TA 3LVYA 1P4TA 2CWQA 3HWBA 3DA3A 6PRNA 1ORMA 3AA0B 1LW1A 2IJCA 4AKMA 5DL7A 2Q0TA 2Y7SA 3POQA 1G90A 4N59A 1IZNB 4GCQA 4LSFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AAE B;  3AA1 B;  1IZN A;  3AAE A;  3AA1 A;  2KXP B;  2KZ7 B;  2KXP A;  2KZ7 A;  5AFU K;  3AA6 B;  3AAA B;  3AA6 A;  5AFU L;  3AAA A;  5ADX K;  3LK3 B;  4AKR B;  3LK3 A;  4AKR A;  3LK4 1;  5ADX L;  3AA7 B;  3AA7 A;  3LK2 B;  3LK4 2;  3LK2 A;  3AA0 B;  3AA0 A;  1IZN B; 
#chains in the Genus database with same CATH topology
 2ODJ A;  2R4O A;  2K4T A;  3AA1 B;  2GMY A;  4GCS A;  4O4U A;  2R4N A;  1BH3 A;  3EMN X;  3G7G A;  2KC0 A;  5ADX K;  3VZW X;  2AF7 A;  4FRT A;  3AA7 B;  4PUX A;  4AYM C;  3POU A;  2W80 C;  1GFN A;  4U9C A;  1IZN A;  5KAI O;  2M07 A;  1OPF A;  2JQY A;  2KXP B;  5DIK A;  2POR A;  2ZLD A;  4AFK A;  4LSE A;  1HXT A;  5ADX L;  2ZFG A;  1PHO A;  5B5E O;  3T24 A;  2X9K A;  4IL6 O;  4UB8 O;  1QJ9 A;  3BS0 A;  3PQS A;  4PR7 A;  3SYS A;  4KR4 A;  5G3A A;  2OUW A;  4C00 A;  5IYU A;  3WI5 A;  4JFB A;  7PRN A;  2MNH A;  3GP6 A;  1MM5 A;  1GU9 A;  4KR8 A;  2XG6 A;  3PRN A;  5TIS O;  4AZL A;  5GTH O;  3AAE B;  2XMX A;  3SZD A;  1MM4 A;  4O3W A;  4O3Y A;  3KVD D;  2M06 A;  4N58 A;  2XE2 A;  4O4X A;  1OSM A;  3NJT A;  3AA0 B;  1LW1 A;  4N59 A;  3JCU O;  4AUI A;  2KZ7 B;  4GHB A;  4F4B A;  3JTY A;  5B66 O;  3RBH A;  3D7I A;  2FGQ X;  2R88 A;  5JDP A;  4AKR B;  2JN8 A;  4D5U A;  3PGU A;  4XNL A;  2XE5 A;  1BT9 A;  1VKE A;  2R8A A;  2PFX A;  1KNC A;  2OMF A;  3A0H O;  4G9Q A;  3AA1 A;  8PRN A;  2O4D A;  3SY7 A;  2Y0K A;  3DWO X;  2JMM A;  1Q9F A;  4O3Z A;  3LK3 B;  4GF4 A;  4FSO A;  3SZV A;  4AYN A;  2W81 C;  3AA7 A;  2KDY A;  4FMS A;  1T1L A;  5DL8 A;  2R4P A;  1HXU A;  5G38 A;  3NSG A;  2ES9 A;  4RL9 A;  2KXP A;  3PQU A;  5T5F A;  2F1T A;  5EE2 A;  1T16 A;  1QJ8 A;  3BRY A;  3HW9 A;  2O4V A;  2R89 A;  3QRC A;  5DL6 A;  2K0L A;  3C1L A;  1H6S 1;  3HOE A;  1E54 A;  3V8U A;  3DWN A;  2Y0L A;  4FSP A;  4KRA A;  3BEY A;  2XTR A;  1YS5 A;  2QTK A;  2LFU A;  1PRN A;  1THQ A;  2QEU A;  3LVY A;  1P4T A;  2IWW A;  2F1C X;  5DL7 A;  2Q0T A;  2Y7S A;  4GCQ A;  5D5D A;  3AAE A;  4K3C A;  3SY9 A;  5AFU K;  1BXW A;  3AAA B;  5KAF O;  2PRN A;  3TZG A;  4FQE A;  3VE1 A;  2WVP A;  4RLC A;  3DA4 A;  5GTI O;  4E1S A;  3T20 A;  4D64 A;  2F1V A;  4AYE C;  3VY9 X;  3LK2 B;  2N2L A;  3AA0 A;  4FZL A;  4LSI A;  3UAQ A;  1ZHZ A;  2FGR A;  4FES A;  2KZ7 A;  3POX A;  5DIP A;  4FOZ A;  5AFU L;  3C5O A;  4FUV A;  1S5L O;  4AKR A;  3O0E A;  4N74 A;  4G76 A;  1ZHX A;  2YNK A;  5PRN A;  4C4V B;  4XNK A;  4K3B A;  4BUM X;  3VZU X;  4O49 A;  4QQ1 A;  3AA6 B;  2J4U P;  3PGS A;  3WI4 A;  2PRR A;  3LK3 A;  5G39 A;  5DL5 A;  4N75 A;  4O3X B;  3SYB A;  2AXT O;  3VZT X;  2GE4 A;  1ZHW A;  2Y0H A;  3UU2 A;  2WJQ A;  4AYI D;  2XE1 A;  4E1T A;  5FVN A;  4Z3T A;  2IWV A;  3A0B O;  5E79 O;  6PRN A;  5H2F O;  1G90 A;  1IZN B;  4LSF A;  3WU2 O;  4FT6 A;  3QRA A;  3UPG A;  1Q9G A;  2XTQ A;  2Y2X A;  3LK4 1;  3A2S X;  3BRZ A;  1MPF A;  4C69 X;  3LK4 2;  3VE2 A;  2XE3 A;  4RJW A;  3FYX A;  2R4L A;  2X27 X;  1GFM A;  3DZM A;  2YPV A;  3K19 A;  4JCH A;  4FZN A;  4CTD A;  3AAA A;  4D65 A;  2N2M A;  3PF1 A;  4FZM A;  4B61 A;  1GFP A;  4UB6 O;  3LK2 A;  2LHF A;  4PJ0 O;  2OYO A;  4RLB A;  4FRX A;  3KZI O;  3PGR A;  4RJX A;  1ZHT A;  1P8C A;  5G26 A;  4AYD C;  5GV0 A;  3HOL A;  2J1N A;  1ZHY A;  4G75 A;  1GFQ A;  1HXX A;  4C4V A;  3T0S A;  2ERV A;  2MHL A;  1QJP A;  3AA6 A;  1ME5 A;  4GCP A;  3POR A;  2WJR A;  4LSH A;  1GFO A;  3VY8 X;  3HWB A;  2CWQ A;  3DA3 A;  1ORM A;  2IJC A;  4AKM A;  3POQ A; 
#chains in the Genus database with same CATH homology
 2ODJ A;  3AA1 B;  2K4T A;  5D5D A;  3AAE A;  4FT6 A;  4AUI A;  2KZ7 B;  4GHB A;  4F4B A;  3QRA A;  2GMY A;  3SY9 A;  4GCS A;  4O4U A;  5AFU K;  1BH3 A;  3EMN X;  3G7G A;  3JTY A;  1BXW A;  2KC0 A;  3AAA B;  3D7I A;  2FGQ X;  2PRN A;  3RBH A;  3UPG A;  5JDP A;  5ADX K;  1Q9G A;  3TZG A;  3VZW X;  2XTQ A;  4AKR B;  2JN8 A;  2Y2X A;  3VE1 A;  2AF7 A;  3LK4 1;  3A2S X;  3DA4 A;  4FRT A;  4RLC A;  3AA7 B;  4E1S A;  4D5U A;  3T20 A;  4D64 A;  1MPF A;  2F1V A;  4XNL A;  3VY9 X;  3LK2 B;  4AYE C;  2XE5 A;  4C69 X;  3LK4 2;  4PUX A;  1BT9 A;  1VKE A;  2N2L A;  2XE3 A;  3AA0 A;  4RJW A;  3FYX A;  3VE2 A;  2PFX A;  1KNC A;  2OMF A;  2X27 X;  3POU A;  4FZL A;  4AYM C;  4LSI A;  2W80 C;  1GFN A;  3UAQ A;  4U9C A;  1ZHZ A;  1IZN A;  2M07 A;  1OPF A;  4G9Q A;  3AA1 A;  5DIK A;  2KXP B;  2POR A;  1GFM A;  8PRN A;  2O4D A;  3SY7 A;  2FGR A;  2Y0K A;  4FES A;  2YPV A;  2KZ7 A;  3K19 A;  3POX A;  4JCH A;  5DIP A;  2ZLD A;  2JMM A;  1Q9F A;  4O3Z A;  4AFK A;  4FZN A;  4FOZ A;  5AFU L;  3AAA A;  4LSE A;  3C5O A;  4FUV A;  3LK3 B;  4D65 A;  1HXT A;  4GF4 A;  4AKR A;  4FSO A;  2ZFG A;  5ADX L;  3SZV A;  2N2M A;  3O0E A;  4FZM A;  2W81 C;  4AYN A;  4B61 A;  1GFP A;  3AA7 A;  1PHO A;  4G76 A;  2KDY A;  3LK2 A;  2LHF A;  1ZHX A;  4FMS A;  3T24 A;  2YNK A;  5DL8 A;  5PRN A;  1QJ9 A;  2OYO A;  1HXU A;  4RLB A;  4FRX A;  4XNK A;  3PQS A;  3SYS A;  3NSG A;  4BUM X;  4KR4 A;  2ES9 A;  4RL9 A;  2KXP A;  4RJX A;  3VZU X;  1ZHT A;  4O49 A;  4QQ1 A;  3AA6 B;  1P8C A;  2OUW A;  3PQU A;  5G26 A;  5T5F A;  4AYD C;  2J4U P;  5IYU A;  3WI4 A;  2F1T A;  2PRR A;  5EE2 A;  5GV0 A;  3WI5 A;  3LK3 A;  1QJ8 A;  3HOL A;  4JFB A;  5DL5 A;  2J1N A;  3HW9 A;  2O4V A;  4O3X B;  1ZHY A;  3SYB A;  7PRN A;  2MNH A;  3GP6 A;  1MM5 A;  1GU9 A;  4G75 A;  3VZT X;  1GFQ A;  3QRC A;  4KR8 A;  2XG6 A;  2GE4 A;  3PRN A;  2K0L A;  5DL6 A;  3C1L A;  1H6S 1;  4AZL A;  1HXX A;  3HOE A;  3AAE B;  1E54 A;  3V8U A;  1ZHW A;  2XMX A;  2Y0H A;  3T0S A;  2ERV A;  2Y0L A;  2MHL A;  3SZD A;  1MM4 A;  3UU2 A;  4O3W A;  4FSP A;  4O3Y A;  3KVD D;  4KRA A;  3BEY A;  2M06 A;  4N58 A;  1QJP A;  4AYI D;  2XTR A;  3AA6 A;  2XE2 A;  1ME5 A;  2XE1 A;  4GCP A;  1YS5 A;  2QTK A;  4E1T A;  2LFU A;  3POR A;  4O4X A;  1PRN A;  1THQ A;  4LSH A;  1GFO A;  2QEU A;  3VY8 X;  5FVN A;  1OSM A;  4Z3T A;  3LVY A;  1P4T A;  2CWQ A;  3HWB A;  3DA3 A;  6PRN A;  1ORM A;  3AA0 B;  1LW1 A;  2IJC A;  4AKM A;  5DL7 A;  2Q0T A;  2Y7S A;  3POQ A;  1G90 A;  4N59 A;  1IZN B;  4GCQ A;  4LSF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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