1IZNA

Crystal structure of actin filament capping protein capz
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
275
structure length
275
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of CapZ: structural basis for actin filament barbed end capping
pubmed doi rcsb
molecule tags Protein binding
source organism Gallus gallus
molecule keywords CapZ alpha-1 subunit
total genus 72
structure length 275
sequence length 275
chains with identical sequence C
ec nomenclature
pdb deposition date 2002-10-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 1iznA01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 1iznA02
1IZNB 3LK42 3LK3B 3LK3A 3AA1B 4AKRA 5AFUL 4AKRB 3AA1A 3LK41 3AA0A 2KXPA 3AA6B 2KXPB 3AA0B 3AA6A 3LK2B 3LK2A 3AAAB 3AAAA 5ADXK 5ADXL 2KZ7A 2KZ7B 3AA7A 3AA7B 3AAEB 5AFUK 3AAEA 1IZNA
chains in the Genus database with same CATH superfamily
3SZDA 5FVNA 3LK3A 4AKRB 4E1SA 4IL6O 1S5LO 3PRNA 5H2FO 5GTHO 2AF7A 2ODJA 4CTDA 3NJTA 4LSEA 2M06A 1MM5A 4GHBA 4PR7A 3BS0A 4KR8A 3T20A 2OYOA 5DL7A 3KZIO 3AA6B 2ZFGA 5D5DA 3D7IA 3V8UA 1HXXA 1T1LA 3NSGA 2XE5A 2KZ7A 3DA3A 4AFKA 3HWBA 2XE3A 2F1VA 2N2MA 4G76A 3A0BO 4O3ZA 3WI4A 4C69X 4O4UA 4Z3TA 1GFQA 3VE1A 5DL6A 1ZHZA 3O0EA 3TZGA 5DL5A 2Y7SA 3VZWX 4AKMA 1IZNA 3DWOX 4N58A 3LK3B 5IYUA 4E1TA 3VE2A 1ZHXA 3PF1A 5JDPA 5B66O 2WVPA 2KXPB 1BXWA 1E54A 1P4TA 1G90A 1MPFA 2IWWA 3BEYA 2Y0HA 4FUVA 3PGSA 3BRYA 4AUIA 4C4VB 1T16A 8PRNA 4FOZA 2XG6A 4FQEA 4B61A 3VZUX 4N74A 2MNHA 4FT6A 5G39A 2MHLA 4FSOA 3T24A 3HOLA 1OSMA 4F4BA 2GMYA 4D65A 1P8CA 4O3YA 3A0HO 2J1NA 2XE2A 2K0LA 4JCHA 4D5UA 3HW9A 2KDYA 4U9CA 4AYID 4FRTA 3PGUA 4AYDC 1PHOA 3DZMA 3KVDD 3C5OA 2OMFA 1YS5A 2OUWA 4K3BA 2M07A 3T0SA 1MM4A 4N75A 3LK41 4LSIA 4FZNA 1ZHYA 4XNKA 3SYBA 3SY9A 4QQ1A 4O49A 1GFMA 3AA7A 2QEUA 5B5EO 5G26A 2O4VA 4KR4A 3AAEA 3BRZA 1Q9FA 3UAQA 3PQSA 3JTYA 4AZLA 5DIKA 2WJQA 4RJXA 2XMXA 3AA0B 4G9QA 4RJWA 5KAIO 4O4XA 5E79O 2R4OA 3G7GA 1THQA 2YPVA 2LHFA 2F1TA 1ORMA 3VY9X 1QJ8A 5AFUK 2PRNA 2J4UP 3POUA 4UB8O 4AKRA 3PGRA 3SZVA 2IWVA 2X27X 2W80C 4RLBA 2R88A 5AFUL 1GFNA 5DIPA 2JQYA 2Y2XA 3AA1A 1GFPA 3K19A 3RBHA 2X9KA 2KZ7B 2FGQX 5PRNA 1OPFA 3AAEB 3QRAA 4C00A 4FZLA 1QJ9A 2F1CX 2ZLDA 5TISO 2Q0TA 4GCSA 4GF4A 5T5FA 4KRAA 1HXUA 4BUMX 3POXA 1GU9A 5G38A 3POQA 5EE2A 2QTKA 1H6S1 3A2SX 1QJPA 1ZHTA 2N2LA 2GE4A 1IZNB 3LK42 2PFXA 3SYSA 5DL8A 1BT9A 1VKEA 4AYMC 2Y0KA 3UPGA 2KXPA 2KC0A 4AYNA 2XTRA 4O3WA 4O3XB 1HXTA 4FSPA 2PORA 2CWQA 1ZHWA 4C4VA 2WJRA 2R8AA 2XE1A 2R89A 4RL9A 3QRCA 3AA1B 5KAFO 1KNCA 1GFOA 4GCPA 2R4LA 1LW1A 3LK2A 4D64A 3AAAA 6PRNA 5ADXK 3WU2O 2ERVA 4FESA 2W81C 2YNKA 3EMNX 3FYXA 2AXTO 3GP6A 3SY7A 2PRRA 2IJCA 4FZMA 2O4DA 2XTQA 4RLCA 2JN8A 4AYEC 4PUXA 2JMMA 2ES9A 3UU2A 5ADXL 4FMSA 3C1LA 4N59A 7PRNA 4UB6O 4XNLA 2R4NA 4LSHA 5GV0A 4LSFA 3AA6A 3WI5A 2FGRA 4JFBA 1ME5A 3DA4A 3PQUA 3JCUO 3LVYA 3DWNA 2Y0LA 2K4TA 4G75A 4GCQA 1PRNA 3AA7B 2LFUA 5G3AA 3HOEA 5GTIO 4PJ0O 3AA0A 3LK2B 3AAAB 1Q9GA 3PORA 3VZTX 3VY8X 2R4PA 1BH3A 4FRXA 4K3CA
chains in the Genus database with same CATH topology
3SZDA 2PRNA 2J4UP 5FVNA 8PRNA 3POUA 2XG6A 4FOZA 3LK3A 4RL9A 3QRCA 4B61A 3AA1B 4AKRA 3VZUX 4AKRB 1KNCA 4E1SA 2MNHA 1GFOA 4GCPA 4FT6A 1LW1A 3LK2A 3PRNA 4D64A 3AAAA 2MHLA 5ADXK 3SZVA 6PRNA 4FSOA 2AF7A 3T24A 3HOLA 2ERVA 1OSMA 2ODJA 4FESA 2W81C 2X27X 2YNKA 3EMNX 4F4BA 2GMYA 3FYXA 3GP6A 3SY7A 4LSEA 2PRRA 2IJCA 2M06A 1MM5A 2W80C 4D65A 4RLBA 1P8CA 4GHBA 4O3YA 5AFUL 4FZMA 2O4DA 1GFNA 4KR8A 3T20A 2XTQA 5DIPA 4RLCA 2J1NA 2JN8A 2XE2A 2K0LA 4AYEC 4PUXA 2OYOA 2JMMA 5DL7A 2Y2XA 3AA1A 4JCHA 1GFPA 3AA6B 2ES9A 3K19A 3RBHA 4D5UA 2ZFGA 2KDYA 3D7IA 3HW9A 4U9CA 5D5DA 3UU2A 3V8UA 1HXXA 5ADXL 4FMSA 3C1LA 4FRTA 3NSGA 4N59A 4AYID 7PRNA 2XE5A 2KZ7A 4AYDC 2KZ7B 1PHOA 2FGQX 3DA3A 4AFKA 3KVDD 3C5OA 5PRNA 1OPFA 2OMFA 3AAEB 3QRAA 4XNLA 3HWBA 1YS5A 4FZLA 1QJ9A 2OUWA 2XE3A 2M07A 2F1VA 3T0SA 1MM4A 2ZLDA 4LSHA 2N2MA 4G76A 3LK41 4O3ZA 4LSIA 5GV0A 4LSFA 3WI4A 4FZNA 3AA6A 4O4UA 4C69X 2Q0TA 3WI5A 2FGRA 4JFBA 4GCSA 4GF4A 5T5FA 1ZHYA 1ME5A 4KRAA 3DA4A 3PQUA 1HXUA 4XNKA 3SYBA 3SY9A 3POXA 4QQ1A 4BUMX 4Z3TA 1GFQA 3VE1A 5DL6A 3LVYA 1GU9A 1ZHZA 3O0EA 2Y0LA 4O49A 3POQA 5DL5A 3TZGA 2K4TA 4G75A 5EE2A 2Y7SA 2QTKA 1GFMA 3AA7A 2QEUA 1PRNA 3AA7B 4GCQA 5G26A 1H6S1 3A2SX 1QJPA 1ZHTA 2N2LA 2LFUA 3AAEA 2O4VA 2GE4A 1IZNA 4KR4A 1IZNB 3VZWX 4AKMA 4N58A 1Q9FA 3LK42 3LK3B 5IYUA 3UAQA 2PFXA 4E1TA 3HOEA 3SYSA 3VE2A 3PQSA 1ZHXA 3JTYA 5DL8A 1BT9A 4AZLA 1VKEA 4AYMC 5DIKA 5JDPA 2Y0KA 4RJXA 3UPGA 2XMXA 3AA0A 2KXPA 2KC0A 2KXPB 1BXWA 3AA0B 3LK2B 1E54A 1P4TA 4G9QA 2XTRA 3AAAB 4O3WA 4RJWA 4AYNA 4O3XB 1G90A 1MPFA 1Q9GA 1HXTA 3BEYA 4O4XA 2Y0HA 4FUVA 4FSPA 2PORA 2CWQA 3G7GA 1THQA 3PORA 3VZTX 4AUIA 3VY8X 2YPVA 2LHFA 2F1TA 1ORMA 3VY9X 1BH3A 1ZHWA 4FRXA 1QJ8A 5AFUK 2XE1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IZN B;  3LK4 2;  3LK3 B;  3LK3 A;  3AA1 B;  4AKR A;  5AFU L;  4AKR B;  3AA1 A;  3LK4 1;  3AA0 A;  2KXP A;  3AA6 B;  2KXP B;  3AA0 B;  3AA6 A;  3LK2 B;  3LK2 A;  3AAA B;  3AAA A;  5ADX K;  5ADX L;  2KZ7 A;  2KZ7 B;  3AA7 A;  3AA7 B;  3AAE B;  5AFU K;  3AAE A;  1IZN A; 
#chains in the Genus database with same CATH topology
 3SZD A;  5FVN A;  3LK3 A;  4AKR B;  4E1S A;  4IL6 O;  1S5L O;  3PRN A;  5H2F O;  5GTH O;  2AF7 A;  2ODJ A;  4CTD A;  3NJT A;  4LSE A;  2M06 A;  1MM5 A;  4GHB A;  4PR7 A;  3BS0 A;  4KR8 A;  3T20 A;  2OYO A;  5DL7 A;  3KZI O;  3AA6 B;  2ZFG A;  5D5D A;  3D7I A;  3V8U A;  1HXX A;  1T1L A;  3NSG A;  2XE5 A;  2KZ7 A;  3DA3 A;  4AFK A;  3HWB A;  2XE3 A;  2F1V A;  2N2M A;  4G76 A;  3A0B O;  4O3Z A;  3WI4 A;  4C69 X;  4O4U A;  4Z3T A;  1GFQ A;  3VE1 A;  5DL6 A;  1ZHZ A;  3O0E A;  3TZG A;  5DL5 A;  2Y7S A;  3VZW X;  4AKM A;  1IZN A;  3DWO X;  4N58 A;  3LK3 B;  5IYU A;  4E1T A;  3VE2 A;  1ZHX A;  3PF1 A;  5JDP A;  5B66 O;  2WVP A;  2KXP B;  1BXW A;  1E54 A;  1P4T A;  1G90 A;  1MPF A;  2IWW A;  3BEY A;  2Y0H A;  4FUV A;  3PGS A;  3BRY A;  4AUI A;  4C4V B;  1T16 A;  8PRN A;  4FOZ A;  2XG6 A;  4FQE A;  4B61 A;  3VZU X;  4N74 A;  2MNH A;  4FT6 A;  5G39 A;  2MHL A;  4FSO A;  3T24 A;  3HOL A;  1OSM A;  4F4B A;  2GMY A;  4D65 A;  1P8C A;  4O3Y A;  3A0H O;  2J1N A;  2XE2 A;  2K0L A;  4JCH A;  4D5U A;  3HW9 A;  2KDY A;  4U9C A;  4AYI D;  4FRT A;  3PGU A;  4AYD C;  1PHO A;  3DZM A;  3KVD D;  3C5O A;  2OMF A;  1YS5 A;  2OUW A;  4K3B A;  2M07 A;  3T0S A;  1MM4 A;  4N75 A;  3LK4 1;  4LSI A;  4FZN A;  1ZHY A;  4XNK A;  3SYB A;  3SY9 A;  4QQ1 A;  4O49 A;  1GFM A;  3AA7 A;  2QEU A;  5B5E O;  5G26 A;  2O4V A;  4KR4 A;  3AAE A;  3BRZ A;  1Q9F A;  3UAQ A;  3PQS A;  3JTY A;  4AZL A;  5DIK A;  2WJQ A;  4RJX A;  2XMX A;  3AA0 B;  4G9Q A;  4RJW A;  5KAI O;  4O4X A;  5E79 O;  2R4O A;  3G7G A;  1THQ A;  2YPV A;  2LHF A;  2F1T A;  1ORM A;  3VY9 X;  1QJ8 A;  5AFU K;  2PRN A;  2J4U P;  3POU A;  4UB8 O;  4AKR A;  3PGR A;  3SZV A;  2IWV A;  2X27 X;  2W80 C;  4RLB A;  2R88 A;  5AFU L;  1GFN A;  5DIP A;  2JQY A;  2Y2X A;  3AA1 A;  1GFP A;  3K19 A;  3RBH A;  2X9K A;  2KZ7 B;  2FGQ X;  5PRN A;  1OPF A;  3AAE B;  3QRA A;  4C00 A;  4FZL A;  1QJ9 A;  2F1C X;  2ZLD A;  5TIS O;  2Q0T A;  4GCS A;  4GF4 A;  5T5F A;  4KRA A;  1HXU A;  4BUM X;  3POX A;  1GU9 A;  5G38 A;  3POQ A;  5EE2 A;  2QTK A;  1H6S 1;  3A2S X;  1QJP A;  1ZHT A;  2N2L A;  2GE4 A;  1IZN B;  3LK4 2;  2PFX A;  3SYS A;  5DL8 A;  1BT9 A;  1VKE A;  4AYM C;  2Y0K A;  3UPG A;  2KXP A;  2KC0 A;  4AYN A;  2XTR A;  4O3W A;  4O3X B;  1HXT A;  4FSP A;  2POR A;  2CWQ A;  1ZHW A;  4C4V A;  2WJR A;  2R8A A;  2XE1 A;  2R89 A;  4RL9 A;  3QRC A;  3AA1 B;  5KAF O;  1KNC A;  1GFO A;  4GCP A;  2R4L A;  1LW1 A;  3LK2 A;  4D64 A;  3AAA A;  6PRN A;  5ADX K;  3WU2 O;  2ERV A;  4FES A;  2W81 C;  2YNK A;  3EMN X;  3FYX A;  2AXT O;  3GP6 A;  3SY7 A;  2PRR A;  2IJC A;  4FZM A;  2O4D A;  2XTQ A;  4RLC A;  2JN8 A;  4AYE C;  4PUX A;  2JMM A;  2ES9 A;  3UU2 A;  5ADX L;  4FMS A;  3C1L A;  4N59 A;  7PRN A;  4UB6 O;  4XNL A;  2R4N A;  4LSH A;  5GV0 A;  4LSF A;  3AA6 A;  3WI5 A;  2FGR A;  4JFB A;  1ME5 A;  3DA4 A;  3PQU A;  3JCU O;  3LVY A;  3DWN A;  2Y0L A;  2K4T A;  4G75 A;  4GCQ A;  1PRN A;  3AA7 B;  2LFU A;  5G3A A;  3HOE A;  5GTI O;  4PJ0 O;  3AA0 A;  3LK2 B;  3AAA B;  1Q9G A;  3POR A;  3VZT X;  3VY8 X;  2R4P A;  1BH3 A;  4FRX A;  4K3C A; 
#chains in the Genus database with same CATH homology
 3SZD A;  2PRN A;  2J4U P;  5FVN A;  8PRN A;  3POU A;  2XG6 A;  4FOZ A;  3LK3 A;  4RL9 A;  3QRC A;  4B61 A;  3AA1 B;  4AKR A;  3VZU X;  4AKR B;  1KNC A;  4E1S A;  2MNH A;  1GFO A;  4GCP A;  4FT6 A;  1LW1 A;  3LK2 A;  3PRN A;  4D64 A;  3AAA A;  2MHL A;  5ADX K;  3SZV A;  6PRN A;  4FSO A;  2AF7 A;  3T24 A;  3HOL A;  2ERV A;  1OSM A;  2ODJ A;  4FES A;  2W81 C;  2X27 X;  2YNK A;  3EMN X;  4F4B A;  2GMY A;  3FYX A;  3GP6 A;  3SY7 A;  4LSE A;  2PRR A;  2IJC A;  2M06 A;  1MM5 A;  2W80 C;  4D65 A;  4RLB A;  1P8C A;  4GHB A;  4O3Y A;  5AFU L;  4FZM A;  2O4D A;  1GFN A;  4KR8 A;  3T20 A;  2XTQ A;  5DIP A;  4RLC A;  2J1N A;  2JN8 A;  2XE2 A;  2K0L A;  4AYE C;  4PUX A;  2OYO A;  2JMM A;  5DL7 A;  2Y2X A;  3AA1 A;  4JCH A;  1GFP A;  3AA6 B;  2ES9 A;  3K19 A;  3RBH A;  4D5U A;  2ZFG A;  2KDY A;  3D7I A;  3HW9 A;  4U9C A;  5D5D A;  3UU2 A;  3V8U A;  1HXX A;  5ADX L;  4FMS A;  3C1L A;  4FRT A;  3NSG A;  4N59 A;  4AYI D;  7PRN A;  2XE5 A;  2KZ7 A;  4AYD C;  2KZ7 B;  1PHO A;  2FGQ X;  3DA3 A;  4AFK A;  3KVD D;  3C5O A;  5PRN A;  1OPF A;  2OMF A;  3AAE B;  3QRA A;  4XNL A;  3HWB A;  1YS5 A;  4FZL A;  1QJ9 A;  2OUW A;  2XE3 A;  2M07 A;  2F1V A;  3T0S A;  1MM4 A;  2ZLD A;  4LSH A;  2N2M A;  4G76 A;  3LK4 1;  4O3Z A;  4LSI A;  5GV0 A;  4LSF A;  3WI4 A;  4FZN A;  3AA6 A;  4O4U A;  4C69 X;  2Q0T A;  3WI5 A;  2FGR A;  4JFB A;  4GCS A;  4GF4 A;  5T5F A;  1ZHY A;  1ME5 A;  4KRA A;  3DA4 A;  3PQU A;  1HXU A;  4XNK A;  3SYB A;  3SY9 A;  3POX A;  4QQ1 A;  4BUM X;  4Z3T A;  1GFQ A;  3VE1 A;  5DL6 A;  3LVY A;  1GU9 A;  1ZHZ A;  3O0E A;  2Y0L A;  4O49 A;  3POQ A;  5DL5 A;  3TZG A;  2K4T A;  4G75 A;  5EE2 A;  2Y7S A;  2QTK A;  1GFM A;  3AA7 A;  2QEU A;  1PRN A;  3AA7 B;  4GCQ A;  5G26 A;  1H6S 1;  3A2S X;  1QJP A;  1ZHT A;  2N2L A;  2LFU A;  3AAE A;  2O4V A;  2GE4 A;  1IZN A;  4KR4 A;  1IZN B;  3VZW X;  4AKM A;  4N58 A;  1Q9F A;  3LK4 2;  3LK3 B;  5IYU A;  3UAQ A;  2PFX A;  4E1T A;  3HOE A;  3SYS A;  3VE2 A;  3PQS A;  1ZHX A;  3JTY A;  5DL8 A;  1BT9 A;  4AZL A;  1VKE A;  4AYM C;  5DIK A;  5JDP A;  2Y0K A;  4RJX A;  3UPG A;  2XMX A;  3AA0 A;  2KXP A;  2KC0 A;  2KXP B;  1BXW A;  3AA0 B;  3LK2 B;  1E54 A;  1P4T A;  4G9Q A;  2XTR A;  3AAA B;  4O3W A;  4RJW A;  4AYN A;  4O3X B;  1G90 A;  1MPF A;  1Q9G A;  1HXT A;  3BEY A;  4O4X A;  2Y0H A;  4FUV A;  4FSP A;  2POR A;  2CWQ A;  3G7G A;  1THQ A;  3POR A;  3VZT X;  4AUI A;  3VY8 X;  2YPV A;  2LHF A;  2F1T A;  1ORM A;  3VY9 X;  1BH3 A;  1ZHW A;  4FRX A;  1QJ8 A;  5AFU K;  2XE1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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