3AAE | Genus

Total Genus 77

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	77
sequence length	270
structure length	270
Chain Sequence	RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILS

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Protein binding
source organism	Gallus gallus
publication title	Two distinct mechanisms for the regulation of actin capping protein-competitive or allosteric inhibitions rcsb
molecule keywords	F-actin-capping protein subunit alpha-1
total genus	77
structure length	270
sequence length	270
chains with identical sequence	C, E, G, I
ec nomenclature
pdb deposition date	2009-11-16

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01267	F-actin_cap_A	F-actin capping protein alpha subunit

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.1290.20	Mainly Alpha	Up-down Bundle	AhpD-like	AhpD-like	3aaeA01
2.40.160.80	Mainly Beta	Beta Barrel	Porin	Porin	3aaeA02

3LK3B 3AA6A 5ADXL 3AAEA 3AA7A 2KZ7A 1IZNB 3AA1B 3AA0B 3LK2A 2KXPA 3AA6B 3AAEB 3AA7B 2KZ7B 5AFUL 4AKRA 3AAAA 5ADXK 3LK2B 2KXPB 3LK3A 1IZNA 3LK42 4AKRB 3LK41 3AAAB 3AA1A 5AFUK 3AA0A
chains in the Genus database with same CATH superfamily

3VZWX 3TZGA 3PGRA 5JDPA 2IWVA 2R89A 2IJCA 3DWOX 5GTIO 4PJ0O 2O4DA 4AZLA 2JQYA 2ERVA 1T1LA 2XE5A 3PGSA 1ZHYA 1Q9GA 3SZDA 3QRAA 2Y0LA 3BRZA 4AKRB 3UAQA 2PRNA 1MPFA 4JFBA 3QRCA 5AFUK 3BS0A 4G9QA 5G26A 1HXUA 3NJTA 5IYUA 1Q9FA 1PHOA 4AYMC 3DWNA 5DIKA 3LK41 4G75A 2AF7A 2FGRA 4C69X 1GU9A 2GE4A 3GP6A 3LK2A 5DIPA 1THQA 3SYBA 1QJ8A 3T0SA 4RJWA 5TISO 4FOZA 4RLBA 5PRNA 3VY8X 4GHBA 2XTQA 3PF1A 2XE2A 2F1CX 4RJXA 4KR8A 4FZLA 4UB8O 5EE2A 3PORA 4FESA 5KAFO 4FT6A 3AA1A 3BEYA 4E1SA 4U9CA 4GCPA 2X9KA 3SY9A 2MNHA 6PRNA 4K3CA 3T20A 1ORMA 1QJ9A 2ODJA 4N58A 3A0BO 3LK2B 3PRNA 4FQEA 5B66O 4KR4A 2R88A 1GFQA 4RL9A 2KZ7A 1T16A 2YPVA 4UB6O 3T24A 3HOEA 1GFOA 2PFXA 3BRYA 3POQA 4AYDC 2F1TA 2J1NA 3UPGA 1MM4A 4AYNA 2R8AA 1GFMA 2ZFGA 5ADXL 3SY7A 1LW1A 3AA1B 2W81C 1GFNA 1S5LO 1P8CA 2ES9A 4O3WA 1E54A 3HW9A 4O4UA 2N2LA 2R4NA 3AA0A 2K0LA 4FUVA 5KAIO 2QEUA 2GMYA 5DL8A 3EMNX 2KZ7B 5AFUL 1KNCA 3AAAA 2Y2XA 4O3ZA 4AKMA 2XE3A 4D65A 3KZIO 2QTKA 3PQSA 3G7GA 2O4VA 4QQ1A 5GV0A 3HWBA 4B61A 1HXXA 2XMXA 3JCUO 3VE2A 2XG6A 2MHLA 4AFKA 3LVYA 2K4TA 8PRNA 2OUWA 4LSEA 2Q0TA 5DL7A 2FGQX 4O4XA 1ZHXA 2LHFA 4D5UA 4XNLA 4FRXA 2IWWA 4Z3TA 1QJPA 2R4LA 5DL6A 3RBHA 3AA7A 4RLCA 3UU2A 3VZUX 3AA0B 3K19A 1OSMA 2YNKA 1ZHZA 4C4VA 4PUXA 3NSGA 4AYID 1ME5A 2JN8A 2ZLDA 3DA3A 2R4OA 5FVNA 3AAAB 1VKEA 4D64A 4E1TA 4N75A 3AAEA 4GCQA 1ZHWA 4CTDA 1YS5A 3DZMA 2JMMA 5G39A 2WVPA 2Y7SA 3C5OA 2PRRA 3C1LA 1IZNA 2WJRA 3POUA 5G3AA 4PR7A 2AXTO 5T5FA 1ZHTA 2XE1A 4K3BA 1MM5A 3AA7B 2W80C 2KC0A 3O0EA 3KVDD 4C4VB 2R4PA 1BH3A 3WI4A 3A0HO 3D7IA 1G90A 4LSIA 1P4TA 4LSHA 2Y0HA 3POXA 2KXPA 3AAEB 4LSFA 2J4UP 4FZNA 3V8UA 3LK3A 4O3XB 4FZMA 4FRTA 5E79O 3HOLA 3PQUA 2CWQA 5H2FO 5G38A 3AA6A 1IZNB 4F4BA 4BUMX 1H6S1 5DL5A 1PRNA 4GF4A 4AYEC 4FMSA 4N59A 5GTHO 3DA4A 4C00A 4O49A 2Y0KA 5D5DA 3WI5A 1HXTA 4KRAA 4O3YA 2OMFA 4XNKA 4AKRA 4G76A 2M06A 1BT9A 1OPFA 3A2SX 2KXPB 3VY9X 3WU2O 3JTYA 4GCSA 3VZTX 3SZVA 3LK3B 2WJQA 3VE1A 1BXWA 4JCHA 1GFPA 2XTRA 4AUIA 3AA6B 3FYXA 2M07A 4FSPA 4IL6O 4FSOA 2KDYA 5ADXK 2N2MA 4N74A 3LK42 2LFUA 3SYSA 7PRNA 2OYOA 2PORA 2F1VA 2X27X 5B5EO 3PGUA
chains in the Genus database with same CATH topology

1G90A 4LSIA 3VZWX 4E1SA 1P4TA 4U9CA 3TZGA 2XMXA 5JDPA 3VE2A 4GCPA 2IJCA 4LSHA 3SY9A 2XG6A 2MNHA 2Y0HA 6PRNA 3T20A 1ORMA 3POXA 2MHLA 2KXPA 2O4DA 1QJ9A 3LVYA 2K4TA 2ODJA 3AAEB 4N58A 4AFKA 2OUWA 4LSEA 4AZLA 8PRNA 2Q0TA 4LSFA 2ERVA 5DL7A 2J4UP 2FGQX 2XE5A 4O4XA 3LK2B 4FZNA 1ZHXA 3V8UA 1ZHYA 1Q9GA 2LHFA 3QRAA 2Y0LA 3LK3A 3SZDA 4D5UA 4O3XB 3PRNA 4FRTA 4FZMA 4XNLA 4AKRB 3HOLA 4FRXA 4KR4A 3UAQA 2PRNA 2CWQA 3PQUA 4Z3TA 1MPFA 4JFBA 3QRCA 5AFUK 1GFQA 1QJPA 4RL9A 4G9QA 5G26A 3AA6A 5DL6A 3RBHA 3AA7A 2KZ7A 1IZNB 1HXUA 4RLCA 4F4BA 4BUMX 3UU2A 1H6S1 2YPVA 3VZUX 3T24A 3AA0B 5IYUA 5DL5A 3K19A 1Q9FA 3HOEA 1OSMA 1PRNA 2YNKA 1ZHZA 4GF4A 1PHOA 1GFOA 4AYMC 4PUXA 3NSGA 4AYID 4AYEC 1ME5A 2PFXA 4AYDC 3POQA 2JN8A 5DIKA 2ZLDA 3DA3A 4FMSA 2F1TA 5FVNA 3LK41 3AAAB 4G75A 1VKEA 2AF7A 4N59A 2J1NA 3DA4A 2FGRA 4C69X 3UPGA 1MM4A 4D64A 4E1TA 4AYNA 1GFMA 2ZFGA 4O49A 3AAEA 5ADXL 1GU9A 4GCQA 2Y0KA 1ZHWA 3SY7A 1LW1A 5D5DA 3AA1B 2W81C 2GE4A 3WI5A 3GP6A 1GFNA 1HXTA 1YS5A 3LK2A 5DIPA 4KRAA 1THQA 2JMMA 1P8CA 4O3YA 2OMFA 4XNKA 4AKRA 4G76A 3SYBA 2M06A 1BT9A 1OPFA 3A2SX 2ES9A 1QJ8A 4O3WA 1E54A 2KXPB 2Y7SA 3C5OA 2PRRA 3C1LA 3T0SA 3VY9X 1IZNA 3HW9A 3POUA 3JTYA 4RJWA 4GCSA 3VZTX 4O4UA 2N2LA 3SZVA 3AA0A 4FOZA 3LK3B 2K0LA 4RLBA 4FUVA 3VE1A 1BXWA 4JCHA 2QEUA 5PRNA 5T5FA 1GFPA 1ZHTA 2GMYA 2XE1A 2XTRA 4AUIA 3VY8X 5DL8A 3AA6B 1MM5A 3EMNX 3AA7B 2KZ7B 2W80C 2M07A 2XTQA 3FYXA 4GHBA 1KNCA 4FSPA 5AFUL 3AAAA 2KC0A 2KDYA 2XE2A 2Y2XA 3O0EA 4FSOA 5ADXK 2XE3A 4O3ZA 4AKMA 4D65A 2N2MA 2QTKA 3PQSA 4RJXA 3G7GA 2O4VA 3KVDD 4QQ1A 4KR8A 4FZLA 3LK42 2LFUA 3SYSA 7PRNA 5EE2A 3PORA 2OYOA 4FESA 4FT6A 2PORA 5GV0A 3AA1A 3HWBA 1BH3A 2F1VA 4B61A 3WI4A 2X27X 3BEYA 3D7IA 1HXXA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 3LK3 B;  3AA6 A;  5ADX L;  3AAE A;  3AA7 A;  2KZ7 A;  1IZN B;  3AA1 B;  3AA0 B;  3LK2 A;  2KXP A;  3AA6 B;  3AAE B;  3AA7 B;  2KZ7 B;  5AFU L;  4AKR A;  3AAA A;  5ADX K;  3LK2 B;  2KXP B;  3LK3 A;  1IZN A;  3LK4 2;  4AKR B;  3LK4 1;  3AAA B;  3AA1 A;  5AFU K;  3AA0 A; 
#chains in the Genus database with same CATH topology
 3VZW X;  3TZG A;  3PGR A;  5JDP A;  2IWV A;  2R89 A;  2IJC A;  3DWO X;  5GTI O;  4PJ0 O;  2O4D A;  4AZL A;  2JQY A;  2ERV A;  1T1L A;  2XE5 A;  3PGS A;  1ZHY A;  1Q9G A;  3SZD A;  3QRA A;  2Y0L A;  3BRZ A;  4AKR B;  3UAQ A;  2PRN A;  1MPF A;  4JFB A;  3QRC A;  5AFU K;  3BS0 A;  4G9Q A;  5G26 A;  1HXU A;  3NJT A;  5IYU A;  1Q9F A;  1PHO A;  4AYM C;  3DWN A;  5DIK A;  3LK4 1;  4G75 A;  2AF7 A;  2FGR A;  4C69 X;  1GU9 A;  2GE4 A;  3GP6 A;  3LK2 A;  5DIP A;  1THQ A;  3SYB A;  1QJ8 A;  3T0S A;  4RJW A;  5TIS O;  4FOZ A;  4RLB A;  5PRN A;  3VY8 X;  4GHB A;  2XTQ A;  3PF1 A;  2XE2 A;  2F1C X;  4RJX A;  4KR8 A;  4FZL A;  4UB8 O;  5EE2 A;  3POR A;  4FES A;  5KAF O;  4FT6 A;  3AA1 A;  3BEY A;  4E1S A;  4U9C A;  4GCP A;  2X9K A;  3SY9 A;  2MNH A;  6PRN A;  4K3C A;  3T20 A;  1ORM A;  1QJ9 A;  2ODJ A;  4N58 A;  3A0B O;  3LK2 B;  3PRN A;  4FQE A;  5B66 O;  4KR4 A;  2R88 A;  1GFQ A;  4RL9 A;  2KZ7 A;  1T16 A;  2YPV A;  4UB6 O;  3T24 A;  3HOE A;  1GFO A;  2PFX A;  3BRY A;  3POQ A;  4AYD C;  2F1T A;  2J1N A;  3UPG A;  1MM4 A;  4AYN A;  2R8A A;  1GFM A;  2ZFG A;  5ADX L;  3SY7 A;  1LW1 A;  3AA1 B;  2W81 C;  1GFN A;  1S5L O;  1P8C A;  2ES9 A;  4O3W A;  1E54 A;  3HW9 A;  4O4U A;  2N2L A;  2R4N A;  3AA0 A;  2K0L A;  4FUV A;  5KAI O;  2QEU A;  2GMY A;  5DL8 A;  3EMN X;  2KZ7 B;  5AFU L;  1KNC A;  3AAA A;  2Y2X A;  4O3Z A;  4AKM A;  2XE3 A;  4D65 A;  3KZI O;  2QTK A;  3PQS A;  3G7G A;  2O4V A;  4QQ1 A;  5GV0 A;  3HWB A;  4B61 A;  1HXX A;  2XMX A;  3JCU O;  3VE2 A;  2XG6 A;  2MHL A;  4AFK A;  3LVY A;  2K4T A;  8PRN A;  2OUW A;  4LSE A;  2Q0T A;  5DL7 A;  2FGQ X;  4O4X A;  1ZHX A;  2LHF A;  4D5U A;  4XNL A;  4FRX A;  2IWW A;  4Z3T A;  1QJP A;  2R4L A;  5DL6 A;  3RBH A;  3AA7 A;  4RLC A;  3UU2 A;  3VZU X;  3AA0 B;  3K19 A;  1OSM A;  2YNK A;  1ZHZ A;  4C4V A;  4PUX A;  3NSG A;  4AYI D;  1ME5 A;  2JN8 A;  2ZLD A;  3DA3 A;  2R4O A;  5FVN A;  3AAA B;  1VKE A;  4D64 A;  4E1T A;  4N75 A;  3AAE A;  4GCQ A;  1ZHW A;  4CTD A;  1YS5 A;  3DZM A;  2JMM A;  5G39 A;  2WVP A;  2Y7S A;  3C5O A;  2PRR A;  3C1L A;  1IZN A;  2WJR A;  3POU A;  5G3A A;  4PR7 A;  2AXT O;  5T5F A;  1ZHT A;  2XE1 A;  4K3B A;  1MM5 A;  3AA7 B;  2W80 C;  2KC0 A;  3O0E A;  3KVD D;  4C4V B;  2R4P A;  1BH3 A;  3WI4 A;  3A0H O;  3D7I A;  1G90 A;  4LSI A;  1P4T A;  4LSH A;  2Y0H A;  3POX A;  2KXP A;  3AAE B;  4LSF A;  2J4U P;  4FZN A;  3V8U A;  3LK3 A;  4O3X B;  4FZM A;  4FRT A;  5E79 O;  3HOL A;  3PQU A;  2CWQ A;  5H2F O;  5G38 A;  3AA6 A;  1IZN B;  4F4B A;  4BUM X;  1H6S 1;  5DL5 A;  1PRN A;  4GF4 A;  4AYE C;  4FMS A;  4N59 A;  5GTH O;  3DA4 A;  4C00 A;  4O49 A;  2Y0K A;  5D5D A;  3WI5 A;  1HXT A;  4KRA A;  4O3Y A;  2OMF A;  4XNK A;  4AKR A;  4G76 A;  2M06 A;  1BT9 A;  1OPF A;  3A2S X;  2KXP B;  3VY9 X;  3WU2 O;  3JTY A;  4GCS A;  3VZT X;  3SZV A;  3LK3 B;  2WJQ A;  3VE1 A;  1BXW A;  4JCH A;  1GFP A;  2XTR A;  4AUI A;  3AA6 B;  3FYX A;  2M07 A;  4FSP A;  4IL6 O;  4FSO A;  2KDY A;  5ADX K;  2N2M A;  4N74 A;  3LK4 2;  2LFU A;  3SYS A;  7PRN A;  2OYO A;  2POR A;  2F1V A;  2X27 X;  5B5E O;  3PGU A; 
#chains in the Genus database with same CATH homology
 1G90 A;  4LSI A;  3VZW X;  4E1S A;  1P4T A;  4U9C A;  3TZG A;  2XMX A;  5JDP A;  3VE2 A;  4GCP A;  2IJC A;  4LSH A;  3SY9 A;  2XG6 A;  2MNH A;  2Y0H A;  6PRN A;  3T20 A;  1ORM A;  3POX A;  2MHL A;  2KXP A;  2O4D A;  1QJ9 A;  3LVY A;  2K4T A;  2ODJ A;  3AAE B;  4N58 A;  4AFK A;  2OUW A;  4LSE A;  4AZL A;  8PRN A;  2Q0T A;  4LSF A;  2ERV A;  5DL7 A;  2J4U P;  2FGQ X;  2XE5 A;  4O4X A;  3LK2 B;  4FZN A;  1ZHX A;  3V8U A;  1ZHY A;  1Q9G A;  2LHF A;  3QRA A;  2Y0L A;  3LK3 A;  3SZD A;  4D5U A;  4O3X B;  3PRN A;  4FRT A;  4FZM A;  4XNL A;  4AKR B;  3HOL A;  4FRX A;  4KR4 A;  3UAQ A;  2PRN A;  2CWQ A;  3PQU A;  4Z3T A;  1MPF A;  4JFB A;  3QRC A;  5AFU K;  1GFQ A;  1QJP A;  4RL9 A;  4G9Q A;  5G26 A;  3AA6 A;  5DL6 A;  3RBH A;  3AA7 A;  2KZ7 A;  1IZN B;  1HXU A;  4RLC A;  4F4B A;  4BUM X;  3UU2 A;  1H6S 1;  2YPV A;  3VZU X;  3T24 A;  3AA0 B;  5IYU A;  5DL5 A;  3K19 A;  1Q9F A;  3HOE A;  1OSM A;  1PRN A;  2YNK A;  1ZHZ A;  4GF4 A;  1PHO A;  1GFO A;  4AYM C;  4PUX A;  3NSG A;  4AYI D;  4AYE C;  1ME5 A;  2PFX A;  4AYD C;  3POQ A;  2JN8 A;  5DIK A;  2ZLD A;  3DA3 A;  4FMS A;  2F1T A;  5FVN A;  3LK4 1;  3AAA B;  4G75 A;  1VKE A;  2AF7 A;  4N59 A;  2J1N A;  3DA4 A;  2FGR A;  4C69 X;  3UPG A;  1MM4 A;  4D64 A;  4E1T A;  4AYN A;  1GFM A;  2ZFG A;  4O49 A;  3AAE A;  5ADX L;  1GU9 A;  4GCQ A;  2Y0K A;  1ZHW A;  3SY7 A;  1LW1 A;  5D5D A;  3AA1 B;  2W81 C;  2GE4 A;  3WI5 A;  3GP6 A;  1GFN A;  1HXT A;  1YS5 A;  3LK2 A;  5DIP A;  4KRA A;  1THQ A;  2JMM A;  1P8C A;  4O3Y A;  2OMF A;  4XNK A;  4AKR A;  4G76 A;  3SYB A;  2M06 A;  1BT9 A;  1OPF A;  3A2S X;  2ES9 A;  1QJ8 A;  4O3W A;  1E54 A;  2KXP B;  2Y7S A;  3C5O A;  2PRR A;  3C1L A;  3T0S A;  3VY9 X;  1IZN A;  3HW9 A;  3POU A;  3JTY A;  4RJW A;  4GCS A;  3VZT X;  4O4U A;  2N2L A;  3SZV A;  3AA0 A;  4FOZ A;  3LK3 B;  2K0L A;  4RLB A;  4FUV A;  3VE1 A;  1BXW A;  4JCH A;  2QEU A;  5PRN A;  5T5F A;  1GFP A;  1ZHT A;  2GMY A;  2XE1 A;  2XTR A;  4AUI A;  3VY8 X;  5DL8 A;  3AA6 B;  1MM5 A;  3EMN X;  3AA7 B;  2KZ7 B;  2W80 C;  2M07 A;  2XTQ A;  3FYX A;  4GHB A;  1KNC A;  4FSP A;  5AFU L;  3AAA A;  2KC0 A;  2KDY A;  2XE2 A;  2Y2X A;  3O0E A;  4FSO A;  5ADX K;  2XE3 A;  4O3Z A;  4AKM A;  4D65 A;  2N2M A;  2QTK A;  3PQS A;  4RJX A;  3G7G A;  2O4V A;  3KVD D;  4QQ1 A;  4KR8 A;  4FZL A;  3LK4 2;  2LFU A;  3SYS A;  7PRN A;  5EE2 A;  3POR A;  2OYO A;  4FES A;  4FT6 A;  2POR A;  5GV0 A;  3AA1 A;  3HWB A;  1BH3 A;  2F1V A;  4B61 A;  3WI4 A;  2X27 X;  3BEY A;  3D7I A;  1HXX A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3AAEA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations