3LK3A

Crystal structure of capz bound to the cpi and csi uncapping motifs from carmil
Total Genus 76
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
76
sequence length
270
structure length
266
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDLKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural characterization of a capping protein interaction motif defines a family of actin filament regulators
doi rcsb
molecule tags Protein binding
source organism Gallus gallus
molecule keywords F-actin-capping protein subunit alpha-1
total genus 76
structure length 266
sequence length 270
ec nomenclature
pdb deposition date 2010-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 3lk3A01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 3lk3A02
2KZ7A 2KXPA 3LK3B 3AA1A 4AKRB 3AAAB 3AA6B 1IZNA 2KZ7B 2KXPB 3LK2B 3LK42 3LK41 3AA1B 3AA7A 5AFUL 3AAEA 1IZNB 3AA0A 5ADXL 3LK3A 5AFUK 3AA7B 3LK2A 4AKRA 3AAEB 3AA0B 3AAAA 3AA6A 5ADXK
chains in the Genus database with same CATH superfamily
2KZ7A 7PRNA 4D64A 1P4TA 1ME5A 3VZUX 2YPVA 2OMFA 2AF7A 5E79O 2F1TA 4FQEA 3DWNA 3UPGA 2XTRA 1KNCA 3AA7B 2JQYA 3AA0B 4PR7A 1ORMA 5EE2A 4JFBA 3DA4A 2OUWA 4AYID 3AA1A 2XE2A 3LK2B 2Y2XA 2X9KA 3TZGA 4O49A 3T20A 3KVDD 5FVNA 3EMNX 4AUIA 3POUA 5G3AA 4AKRB 4C4VB 4AYMC 3PGUA 5GTHO 4GF4A 1ZHYA 2JMMA 4N58A 3DZMA 5G38A 2LHFA 4C00A 4FZNA 4B61A 4RLCA 3POQA 4K3CA 1HXUA 5KAIO 5D5DA 4FZLA 2KXPA 4FOZA 2WJRA 5GTIO 2R4PA 1BH3A 1Q9GA 1VKEA 4G9QA 3GP6A 2IJCA 2FGQX 1GFMA 2XMXA 4FRTA 3PRNA 3T0SA 2PORA 1Q9FA 4AYNA 5AFUK 5DIKA 3AAAB 2ODJA 3AA6B 2KZ7B 4K3BA 3T24A 2MHLA 2WJQA 4GHBA 2FGRA 4FZMA 3BS0A 3AAEA 3BEYA 1HXTA 3KZIO 1GFOA 2QTKA 4KR4A 1OSMA 5G39A 3WI5A 1T1LA 2X27X 3BRZA 4G75A 2N2LA 3G7GA 4O3ZA 3AA1B 2R4OA 5AFUL 2F1CX 1H6S1 3PORA 3WI4A 3PQSA 2ZFGA 3JTYA 4PUXA 4LSFA 2R89A 4O3WA 2K4TA 2IWWA 4FT6A 3PGRA 3D7IA 5T5FA 5DL6A 2GMYA 3SY7A 2WVPA 5B66O 2KDYA 3VZTX 1ZHXA 3HWBA 4LSHA 3SY9A 4G76A 3PQUA 4FESA 4IL6O 1OPFA 2KXPB 1BXWA 2AXTO 2Y7SA 3LK41 2R4NA 4UB8O 1QJ8A 2YNKA 2MNHA 2XTQA 3JCUO 4GCQA 4AKMA 5PRNA 2M07A 4FRXA 3VY9X 1YS5A 4RJXA 1ZHZA 4UB6O 3BRYA 4Z3TA 2ERVA 5GV0A 6PRNA 3QRAA 5IYUA 2XE1A 3AAEB 5DL5A 1QJPA 1MM5A 1E54A 5B5EO 1IZNA 3UAQA 3VZWX 4D5UA 3VE1A 4GCSA 1G90A 3PF1A 3LK3A 5H2FO 1ZHWA 2N2MA 4AYEC 4AFKA 4O4XA 3HW9A 2F1VA 4E1TA 4F4BA 4N75A 4N74A 1S5LO 4JCHA 3DWOX 3HOEA 4LSEA 2ZLDA 4RJWA 3UU2A 4O3YA 4XNLA 3RBHA 3V8UA 3FYXA 2Y0KA 2Y0LA 4FUVA 2R88A 3DA3A 3VY8X 3PGSA 5JDPA 2W80C 1GU9A 3SYBA 1HXXA 4O4UA 2ES9A 5KAFO 2KC0A 2O4VA 3O0EA 3VE2A 4C69X 2K0LA 8PRNA 3SZVA 3SYSA 4AYDC 3K19A 2Y0HA 2LFUA 4FSPA 1MPFA 1PRNA 2XG6A 2J4UP 3AA7A 4PJ0O 4KR8A 3AA0A 1THQA 2PRNA 2PRRA 3QRCA 2IWVA 4RLBA 4D65A 5G26A 3LK2A 1GFQA 5TISO 3A2SX 2GE4A 4O3XB 4BUMX 2M06A 2XE5A 2OYOA 3C5OA 4CTDA 1GFNA 1IZNB 1ZHTA 1GFPA 4GCPA 2O4DA 1QJ9A 2CWQA 4C4VA 4AKRA 1P8CA 5ADXK 3LVYA 3LK3B 4U9CA 3A0HO 4LSIA 3LK42 3WU2O 4E1SA 1T16A 2J1NA 3NJTA 4N59A 1MM4A 4FSOA 2PFXA 2W81C 3SZDA 2XE3A 2Q0TA 1LW1A 4QQ1A 1BT9A 4XNKA 3HOLA 2R4LA 4KRAA 3C1LA 5DL7A 3NSGA 4FMSA 5DL8A 4RL9A 2JN8A 3POXA 5ADXL 3A0BO 5DIPA 2QEUA 2R8AA 4AZLA 1PHOA 3AAAA 3AA6A
chains in the Genus database with same CATH topology
2KZ7A 4AKMA 5PRNA 7PRNA 4D64A 1P4TA 5DIKA 2LFUA 1ME5A 2M07A 4FSPA 4FRXA 3VY9X 1YS5A 2ODJA 2YPVA 2KZ7B 3AA6B 2OMFA 2AF7A 3AAAB 2F1TA 3VZUX 1MPFA 4RJXA 1PRNA 1ZHZA 2MHLA 3T24A 2XG6A 4GHBA 2FGRA 2J4UP 3AA7A 3UPGA 4FZMA 4KR8A 3AAEA 3BEYA 1HXTA 3AA0A 4Z3TA 2XTRA 2ERVA 1THQA 5GV0A 2PRNA 2PRRA 3QRCA 1KNCA 6PRNA 3QRAA 3AA7B 4RLBA 4D65A 5G26A 1GFOA 2QTKA 2XE1A 3AAEB 5IYUA 3AA0B 5DL5A 1QJPA 4KR4A 3LK2A 1GFQA 1ORMA 1OSMA 5EE2A 3A2SX 4JFBA 2GE4A 1MM5A 4O3XB 3DA4A 3WI5A 2OUWA 2X27X 4AYID 4G75A 3AA1A 1E54A 2XE2A 4BUMX 1IZNA 3LK2B 2M06A 2Y2XA 3UAQA 2N2LA 3VZWX 3TZGA 4O49A 3T20A 2XE5A 3G7GA 4D5UA 4O3ZA 3VE1A 2OYOA 3AA1B 3C5OA 4GCSA 5AFUL 1G90A 1GFNA 1IZNB 1ZHTA 1H6S1 1GFPA 3PORA 3KVDD 5FVNA 4GCPA 3WI4A 2O4DA 1QJ9A 3PQSA 3EMNX 3LK3A 2ZFGA 3JTYA 4PUXA 2CWQA 4AKRA 1P8CA 4LSFA 5ADXK 3LVYA 1ZHWA 2N2MA 4AYEC 3LK3B 4O3WA 4AUIA 3POUA 4AFKA 2K4TA 4AKRB 4O4XA 4U9CA 4AYMC 3HW9A 4LSIA 2F1VA 4E1TA 3LK42 4FT6A 4GF4A 4F4BA 1ZHYA 2JMMA 4N58A 4JCHA 3D7IA 3HOEA 2LHFA 5T5FA 4LSEA 4E1SA 5DL6A 2GMYA 2ZLDA 4RJWA 3SY7A 4FZNA 3UU2A 4O3YA 2J1NA 4XNLA 3RBHA 3V8UA 4B61A 4N59A 3FYXA 4RLCA 1MM4A 3POQA 4FSOA 2PFXA 1HXUA 2Y0KA 2Y0LA 2KDYA 4FUVA 5D5DA 3DA3A 3VY8X 4FZLA 2KXPA 2W81C 5JDPA 2W80C 1ZHXA 3HWBA 4FOZA 4LSHA 3SZDA 2XE3A 3SY9A 3VZTX 4G76A 2Q0TA 1BH3A 1GU9A 1Q9GA 1LW1A 3PQUA 4QQ1A 1VKEA 4G9QA 1HXXA 3SYBA 4FESA 1OPFA 1BT9A 4O4UA 4XNKA 2ES9A 3HOLA 3GP6A 2KXPB 1BXWA 2IJCA 4KRAA 3C1LA 2FGQX 2Y7SA 5DL7A 1GFMA 3NSGA 2KC0A 4FMSA 5DL8A 3LK41 2O4VA 2XMXA 4RL9A 4FRTA 3PRNA 3O0EA 3T0SA 2JN8A 1QJ8A 1Q9FA 2PORA 3POXA 3VE2A 4AYNA 4C69X 2YNKA 2K0LA 8PRNA 2MNHA 5ADXL 5DIPA 5AFUK 3SZVA 2XTQA 3SYSA 2QEUA 4AYDC 3K19A 2Y0HA 4AZLA 4GCQA 1PHOA 3AAAA 3AA6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KZ7 A;  2KXP A;  3LK3 B;  3AA1 A;  4AKR B;  3AAA B;  3AA6 B;  1IZN A;  2KZ7 B;  2KXP B;  3LK2 B;  3LK4 2;  3LK4 1;  3AA1 B;  3AA7 A;  5AFU L;  3AAE A;  1IZN B;  3AA0 A;  5ADX L;  3LK3 A;  5AFU K;  3AA7 B;  3LK2 A;  4AKR A;  3AAE B;  3AA0 B;  3AAA A;  3AA6 A;  5ADX K; 
#chains in the Genus database with same CATH topology
 2KZ7 A;  7PRN A;  4D64 A;  1P4T A;  1ME5 A;  3VZU X;  2YPV A;  2OMF A;  2AF7 A;  5E79 O;  2F1T A;  4FQE A;  3DWN A;  3UPG A;  2XTR A;  1KNC A;  3AA7 B;  2JQY A;  3AA0 B;  4PR7 A;  1ORM A;  5EE2 A;  4JFB A;  3DA4 A;  2OUW A;  4AYI D;  3AA1 A;  2XE2 A;  3LK2 B;  2Y2X A;  2X9K A;  3TZG A;  4O49 A;  3T20 A;  3KVD D;  5FVN A;  3EMN X;  4AUI A;  3POU A;  5G3A A;  4AKR B;  4C4V B;  4AYM C;  3PGU A;  5GTH O;  4GF4 A;  1ZHY A;  2JMM A;  4N58 A;  3DZM A;  5G38 A;  2LHF A;  4C00 A;  4FZN A;  4B61 A;  4RLC A;  3POQ A;  4K3C A;  1HXU A;  5KAI O;  5D5D A;  4FZL A;  2KXP A;  4FOZ A;  2WJR A;  5GTI O;  2R4P A;  1BH3 A;  1Q9G A;  1VKE A;  4G9Q A;  3GP6 A;  2IJC A;  2FGQ X;  1GFM A;  2XMX A;  4FRT A;  3PRN A;  3T0S A;  2POR A;  1Q9F A;  4AYN A;  5AFU K;  5DIK A;  3AAA B;  2ODJ A;  3AA6 B;  2KZ7 B;  4K3B A;  3T24 A;  2MHL A;  2WJQ A;  4GHB A;  2FGR A;  4FZM A;  3BS0 A;  3AAE A;  3BEY A;  1HXT A;  3KZI O;  1GFO A;  2QTK A;  4KR4 A;  1OSM A;  5G39 A;  3WI5 A;  1T1L A;  2X27 X;  3BRZ A;  4G75 A;  2N2L A;  3G7G A;  4O3Z A;  3AA1 B;  2R4O A;  5AFU L;  2F1C X;  1H6S 1;  3POR A;  3WI4 A;  3PQS A;  2ZFG A;  3JTY A;  4PUX A;  4LSF A;  2R89 A;  4O3W A;  2K4T A;  2IWW A;  4FT6 A;  3PGR A;  3D7I A;  5T5F A;  5DL6 A;  2GMY A;  3SY7 A;  2WVP A;  5B66 O;  2KDY A;  3VZT X;  1ZHX A;  3HWB A;  4LSH A;  3SY9 A;  4G76 A;  3PQU A;  4FES A;  4IL6 O;  1OPF A;  2KXP B;  1BXW A;  2AXT O;  2Y7S A;  3LK4 1;  2R4N A;  4UB8 O;  1QJ8 A;  2YNK A;  2MNH A;  2XTQ A;  3JCU O;  4GCQ A;  4AKM A;  5PRN A;  2M07 A;  4FRX A;  3VY9 X;  1YS5 A;  4RJX A;  1ZHZ A;  4UB6 O;  3BRY A;  4Z3T A;  2ERV A;  5GV0 A;  6PRN A;  3QRA A;  5IYU A;  2XE1 A;  3AAE B;  5DL5 A;  1QJP A;  1MM5 A;  1E54 A;  5B5E O;  1IZN A;  3UAQ A;  3VZW X;  4D5U A;  3VE1 A;  4GCS A;  1G90 A;  3PF1 A;  3LK3 A;  5H2F O;  1ZHW A;  2N2M A;  4AYE C;  4AFK A;  4O4X A;  3HW9 A;  2F1V A;  4E1T A;  4F4B A;  4N75 A;  4N74 A;  1S5L O;  4JCH A;  3DWO X;  3HOE A;  4LSE A;  2ZLD A;  4RJW A;  3UU2 A;  4O3Y A;  4XNL A;  3RBH A;  3V8U A;  3FYX A;  2Y0K A;  2Y0L A;  4FUV A;  2R88 A;  3DA3 A;  3VY8 X;  3PGS A;  5JDP A;  2W80 C;  1GU9 A;  3SYB A;  1HXX A;  4O4U A;  2ES9 A;  5KAF O;  2KC0 A;  2O4V A;  3O0E A;  3VE2 A;  4C69 X;  2K0L A;  8PRN A;  3SZV A;  3SYS A;  4AYD C;  3K19 A;  2Y0H A;  2LFU A;  4FSP A;  1MPF A;  1PRN A;  2XG6 A;  2J4U P;  3AA7 A;  4PJ0 O;  4KR8 A;  3AA0 A;  1THQ A;  2PRN A;  2PRR A;  3QRC A;  2IWV A;  4RLB A;  4D65 A;  5G26 A;  3LK2 A;  1GFQ A;  5TIS O;  3A2S X;  2GE4 A;  4O3X B;  4BUM X;  2M06 A;  2XE5 A;  2OYO A;  3C5O A;  4CTD A;  1GFN A;  1IZN B;  1ZHT A;  1GFP A;  4GCP A;  2O4D A;  1QJ9 A;  2CWQ A;  4C4V A;  4AKR A;  1P8C A;  5ADX K;  3LVY A;  3LK3 B;  4U9C A;  3A0H O;  4LSI A;  3LK4 2;  3WU2 O;  4E1S A;  1T16 A;  2J1N A;  3NJT A;  4N59 A;  1MM4 A;  4FSO A;  2PFX A;  2W81 C;  3SZD A;  2XE3 A;  2Q0T A;  1LW1 A;  4QQ1 A;  1BT9 A;  4XNK A;  3HOL A;  2R4L A;  4KRA A;  3C1L A;  5DL7 A;  3NSG A;  4FMS A;  5DL8 A;  4RL9 A;  2JN8 A;  3POX A;  5ADX L;  3A0B O;  5DIP A;  2QEU A;  2R8A A;  4AZL A;  1PHO A;  3AAA A;  3AA6 A; 
#chains in the Genus database with same CATH homology
 2KZ7 A;  4AKM A;  5PRN A;  7PRN A;  4D64 A;  1P4T A;  5DIK A;  2LFU A;  1ME5 A;  2M07 A;  4FSP A;  4FRX A;  3VY9 X;  1YS5 A;  2ODJ A;  2YPV A;  2KZ7 B;  3AA6 B;  2OMF A;  2AF7 A;  3AAA B;  2F1T A;  3VZU X;  1MPF A;  4RJX A;  1PRN A;  1ZHZ A;  2MHL A;  3T24 A;  2XG6 A;  4GHB A;  2FGR A;  2J4U P;  3AA7 A;  3UPG A;  4FZM A;  4KR8 A;  3AAE A;  3BEY A;  1HXT A;  3AA0 A;  4Z3T A;  2XTR A;  2ERV A;  1THQ A;  5GV0 A;  2PRN A;  2PRR A;  3QRC A;  1KNC A;  6PRN A;  3QRA A;  3AA7 B;  4RLB A;  4D65 A;  5G26 A;  1GFO A;  2QTK A;  2XE1 A;  3AAE B;  5IYU A;  3AA0 B;  5DL5 A;  1QJP A;  4KR4 A;  3LK2 A;  1GFQ A;  1ORM A;  1OSM A;  5EE2 A;  3A2S X;  4JFB A;  2GE4 A;  1MM5 A;  4O3X B;  3DA4 A;  3WI5 A;  2OUW A;  2X27 X;  4AYI D;  4G75 A;  3AA1 A;  1E54 A;  2XE2 A;  4BUM X;  1IZN A;  3LK2 B;  2M06 A;  2Y2X A;  3UAQ A;  2N2L A;  3VZW X;  3TZG A;  4O49 A;  3T20 A;  2XE5 A;  3G7G A;  4D5U A;  4O3Z A;  3VE1 A;  2OYO A;  3AA1 B;  3C5O A;  4GCS A;  5AFU L;  1G90 A;  1GFN A;  1IZN B;  1ZHT A;  1H6S 1;  1GFP A;  3POR A;  3KVD D;  5FVN A;  4GCP A;  3WI4 A;  2O4D A;  1QJ9 A;  3PQS A;  3EMN X;  3LK3 A;  2ZFG A;  3JTY A;  4PUX A;  2CWQ A;  4AKR A;  1P8C A;  4LSF A;  5ADX K;  3LVY A;  1ZHW A;  2N2M A;  4AYE C;  3LK3 B;  4O3W A;  4AUI A;  3POU A;  4AFK A;  2K4T A;  4AKR B;  4O4X A;  4U9C A;  4AYM C;  3HW9 A;  4LSI A;  2F1V A;  4E1T A;  3LK4 2;  4FT6 A;  4GF4 A;  4F4B A;  1ZHY A;  2JMM A;  4N58 A;  4JCH A;  3D7I A;  3HOE A;  2LHF A;  5T5F A;  4LSE A;  4E1S A;  5DL6 A;  2GMY A;  2ZLD A;  4RJW A;  3SY7 A;  4FZN A;  3UU2 A;  4O3Y A;  2J1N A;  4XNL A;  3RBH A;  3V8U A;  4B61 A;  4N59 A;  3FYX A;  4RLC A;  1MM4 A;  3POQ A;  4FSO A;  2PFX A;  1HXU A;  2Y0K A;  2Y0L A;  2KDY A;  4FUV A;  5D5D A;  3DA3 A;  3VY8 X;  4FZL A;  2KXP A;  2W81 C;  5JDP A;  2W80 C;  1ZHX A;  3HWB A;  4FOZ A;  4LSH A;  3SZD A;  2XE3 A;  3SY9 A;  3VZT X;  4G76 A;  2Q0T A;  1BH3 A;  1GU9 A;  1Q9G A;  1LW1 A;  3PQU A;  4QQ1 A;  1VKE A;  4G9Q A;  1HXX A;  3SYB A;  4FES A;  1OPF A;  1BT9 A;  4O4U A;  4XNK A;  2ES9 A;  3HOL A;  3GP6 A;  2KXP B;  1BXW A;  2IJC A;  4KRA A;  3C1L A;  2FGQ X;  2Y7S A;  5DL7 A;  1GFM A;  3NSG A;  2KC0 A;  4FMS A;  5DL8 A;  3LK4 1;  2O4V A;  2XMX A;  4RL9 A;  4FRT A;  3PRN A;  3O0E A;  3T0S A;  2JN8 A;  1QJ8 A;  1Q9F A;  2POR A;  3POX A;  3VE2 A;  4AYN A;  4C69 X;  2YNK A;  2K0L A;  8PRN A;  2MNH A;  5ADX L;  5DIP A;  5AFU K;  3SZV A;  2XTQ A;  3SYS A;  2QEU A;  4AYD C;  3K19 A;  2Y0H A;  4AZL A;  4GCQ A;  1PHO A;  3AAA A;  3AA6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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