3LK41

Crystal structure of capz bound to the uncapping motif from cd2ap
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
269
structure length
269
Chain Sequence
VSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural characterization of a capping protein interaction motif defines a family of actin filament regulators
doi rcsb
molecule tags Protein binding
source organism Gallus gallus
molecule keywords F-actin-capping protein subunit alpha-1
total genus 85
structure length 269
sequence length 269
chains with identical sequence 4, 7, A, D, G, J, M, P, S, V, Y
ec nomenclature
pdb deposition date 2010-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
1 PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 3lk4101
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 3lk4102
3AA1A 3AA7A 1IZNB 3LK2B 3LK41 3AAAB 1IZNA 3LK2A 2KZ7B 3AAAA 2KZ7A 3AA0B 3AA0A 5ADXK 3AAEB 3LK3B 2KXPB 4AKRB 3LK42 3AA1B 3AA7B 5ADXL 3AAEA 5AFUK 3AA6B 2KXPA 4AKRA 3LK3A 3AA6A 5AFUL
chains in the Genus database with same CATH superfamily
4UB8O 3LK41 2R4NA 3VZTX 5T5FA 5DL7A 4D5UA 5B5EO 3A0HO 4O4XA 3DWNA 4KR4A 3PGUA 4K3CA 4O3YA 3RBHA 1Q9FA 3WI5A 4AKRA 3PGRA 2YNKA 4GCPA 1ORMA 2IWVA 4FSPA 3JTYA 5G3AA 4D65A 5DL6A 1BH3A 1GFQA 8PRNA 3T0SA 5GV0A 2MHLA 2F1VA 1GU9A 2JQYA 2R4OA 1GFOA 4G76A 3G7GA 2XE5A 3QRAA 4IL6O 5DIPA 2R8AA 4GHBA 3AAEB 2CWQA 2PFXA 2K4TA 3AA1B 4AZLA 3JCUO 3BRZA 4GF4A 1ME5A 2ERVA 3C1LA 3PRNA 4F4BA 3POQA 1OSMA 4N59A 1HXUA 4FRTA 5ADXK 2GE4A 3LK3B 1H6S1 3AA6B 2YPVA 3VY9X 3POXA 5D5DA 2IJCA 2W80C 4FQEA 4GCQA 3O0EA 4AYNA 1IZNA 4C69X 4N58A 3VY8X 4AFKA 1GFPA 2PRNA 3SZVA 4CTDA 3LVYA 2X27X 2WVPA 4C00A 3AA7A 1GFMA 3T20A 2W81C 2R4LA 2ODJA 3FYXA 2M07A 2IWWA 2Y7SA 2M06A 2OYOA 3SYSA 4E1TA 3PQSA 3PF1A 3BRYA 3LK42 5B66O 2R89A 3TZGA 5AFUK 5E79O 3AA6A 2XE3A 3LK2B 3HWBA 3WU2O 2OUWA 1G90A 5H2FO 2R88A 4FOZA 1ZHWA 3VE1A 2LHFA 1PRNA 1P8CA 4RLBA 4AUIA 3D7IA 2XTQA 4LSFA 3GP6A 2LFUA 4FZNA 4N75A 4FMSA 2ES9A 4PJ0O 3AAAB 5KAFO 3A0BO 3HOEA 1MM5A 1S5LO 5G26A 3NSGA 1VKEA 2Y0LA 2AF7A 4O3WA 3PQUA 3SY7A 3SYBA 3DA4A 3POUA 2Y0KA 3HOLA 2N2LA 5DIKA 5G39A 2QTKA 3C5OA 1MPFA 2KXPB 3DWOX 3K19A 1THQA 2O4VA 3UAQA 1GFNA 5FVNA 2QEUA 4JCHA 4B61A 2XMXA 2JMMA 1QJ8A 3AA0B 4XNKA 4RLCA 1HXTA 4FZLA 3AAEA 5JDPA 5AFUL 3AA1A 2O4DA 1KNCA 1BT9A 2F1CX 1P4TA 7PRNA 4U9CA 4O4UA 4PR7A 4D64A 2Y0HA 3A2SX 4AKMA 1OPFA 3QRCA 2KXPA 4O3XB 3LK3A 1T16A 3KVDD 3SY9A 3BEYA 3VZUX 4RL9A 4UB6O 1YS5A 2Y2XA 4FT6A 3DZMA 4XNLA 4C4VB 3HW9A 4FESA 4LSEA 4LSHA 4RJXA 3AA0A 4FUVA 2K0LA 4LSIA 1BXWA 2OMFA 4O49A 2FGQX 2R4PA 2FGRA 1QJPA 4N74A 2XG6A 3UU2A 1Q9GA 3SZDA 4G75A 5KAIO 3NJTA 4FZMA 5PRNA 4FSOA 5EE2A 4AYEC 4RJWA 1QJ9A 2XE2A 3T24A 3WI4A 4PUXA 5TISO 2J1NA 5ADXL 1ZHZA 4BUMX 3BS0A 1IZNB 1LW1A 1ZHTA 3LK2A 4KR8A 5IYUA 2KZ7B 5DL8A 4C4VA 3VZWX 4AYDC 3AA7B 3VE2A 4GCSA 6PRNA 1T1LA 4KRAA 1ZHXA 2KDYA 2F1TA 4O3ZA 1E54A 4E1SA 5GTHO 3AAAA 2GMYA 3PORA 5GTIO 2J4UP 5G38A 2PORA 4AYID 2JN8A 3PGSA 3V8UA 2WJRA 3KZIO 3UPGA 4FRXA 4AKRB 3DA3A 1MM4A 2N2MA 2ZFGA 4K3BA 1ZHYA 2PRRA 4JFBA 2ZLDA 3EMNX 2XTRA 5DL5A 2KZ7A 1HXXA 4QQ1A 2AXTO 2XE1A 2MNHA 2WJQA 4Z3TA 1PHOA 2Q0TA 2KC0A 2X9KA 4G9QA 4AYMC
chains in the Genus database with same CATH topology
4O3WA 3UU2A 1Q9GA 2W80C 3PQUA 4G75A 4GCQA 3SZDA 3LK41 3VZTX 3O0EA 4FZMA 5PRNA 5T5FA 3SY7A 1IZNA 3SYBA 3DA4A 3POUA 4AYNA 4C69X 5DL7A 4D5UA 2Y0KA 4AYMC 4FSOA 3HOLA 5EE2A 2N2LA 4N58A 4RJWA 5DIKA 1QJ9A 2XE2A 4O4XA 3T24A 3VY8X 3WI4A 1GFPA 2QTKA 4KR4A 4AFKA 4PUXA 2PRNA 3C5OA 2J1NA 3SZVA 1MPFA 4O3YA 2KXPB 3RBHA 1Q9FA 3LVYA 2X27X 5ADXL 1ZHZA 3K19A 4BUMX 3WI5A 4AKRA 1THQA 2O4VA 3UAQA 3AA7A 2YNKA 1GFMA 1IZNB 1LW1A 3T20A 2W81C 1GFNA 1ZHTA 5FVNA 2ODJA 2QEUA 4GCPA 3FYXA 4JCHA 2M07A 3LK2A 1ORMA 4B61A 4KR8A 5IYUA 2KZ7B 2XMXA 2Y7SA 2JMMA 2M06A 1QJ8A 3JTYA 4FSPA 5DL8A 3VZWX 3AA0B 4XNKA 4D65A 5DL6A 4RLCA 2OYOA 1BH3A 1GFQA 3SYSA 8PRNA 4E1TA 1HXTA 4AYEC 3T0SA 3PQSA 5GV0A 2MHLA 3LK42 4FZLA 3AA7B 4AYDC 3AAEA 3TZGA 5AFUK 3VE2A 2F1VA 5JDPA 1GU9A 4GCSA 3AA6A 2XE3A 3AA1A 5AFUL 6PRNA 1GFOA 2O4DA 1KNCA 3LK2B 1BT9A 3HWBA 2OUWA 3G7GA 4G76A 1G90A 4KRAA 1ZHXA 1P4TA 2KDYA 7PRNA 2XE5A 2F1TA 4U9CA 4FOZA 3QRAA 1E54A 4O3ZA 4E1SA 1ZHWA 4O4UA 3VE1A 3AAAA 5DIPA 2LHFA 2GMYA 4D64A 1PRNA 3PORA 1P8CA 2J4UP 2Y0HA 4GHBA 3A2SX 4RLBA 4AUIA 3D7IA 4AKMA 2PORA 3AAEB 2CWQA 2XTQA 2JN8A 4AYID 4LSFA 1OPFA 3V8UA 2PFXA 2K4TA 3UPGA 4FRXA 4AKRB 3GP6A 3AA1B 4AZLA 3DA3A 3QRCA 2KXPA 2LFUA 4O3XB 3LK3A 4FZNA 3KVDD 3SY9A 3BEYA 3VZUX 1MM4A 4GF4A 1ME5A 4RL9A 1YS5A 5D5DA 4FMSA 2Y2XA 2ES9A 2N2MA 2ERVA 3C1LA 4FT6A 2ZFGA 3AAAB 3PRNA 4F4BA 1ZHYA 4XNLA 2PRRA 4JFBA 3HOEA 2ZLDA 3HW9A 3EMNX 3POQA 1MM5A 2XTRA 5DL5A 2KZ7A 1HXXA 4FESA 1OSMA 2XE1A 4QQ1A 4N59A 5G26A 1HXUA 2MNHA 4LSEA 4LSHA 3NSGA 4RJXA 3AA0A 4FRTA 4FUVA 5ADXK 4Z3TA 2K0LA 4LSIA 2GE4A 1VKEA 1BXWA 2OMFA 3LK3B 4O49A 1PHOA 1H6S1 2Q0TA 2FGQX 2KC0A 3AA6B 2YPVA 3VY9X 4G9QA 2FGRA 1QJPA 2Y0LA 2XG6A 3POXA 2AF7A 2IJCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AA1 A;  3AA7 A;  1IZN B;  3LK2 B;  3LK4 1;  3AAA B;  1IZN A;  3LK2 A;  2KZ7 B;  3AAA A;  2KZ7 A;  3AA0 B;  3AA0 A;  5ADX K;  3AAE B;  3LK3 B;  2KXP B;  4AKR B;  3LK4 2;  3AA1 B;  3AA7 B;  5ADX L;  3AAE A;  5AFU K;  3AA6 B;  2KXP A;  4AKR A;  3LK3 A;  3AA6 A;  5AFU L; 
#chains in the Genus database with same CATH topology
 4UB8 O;  3LK4 1;  2R4N A;  3VZT X;  5T5F A;  5DL7 A;  4D5U A;  5B5E O;  3A0H O;  4O4X A;  3DWN A;  4KR4 A;  3PGU A;  4K3C A;  4O3Y A;  3RBH A;  1Q9F A;  3WI5 A;  4AKR A;  3PGR A;  2YNK A;  4GCP A;  1ORM A;  2IWV A;  4FSP A;  3JTY A;  5G3A A;  4D65 A;  5DL6 A;  1BH3 A;  1GFQ A;  8PRN A;  3T0S A;  5GV0 A;  2MHL A;  2F1V A;  1GU9 A;  2JQY A;  2R4O A;  1GFO A;  4G76 A;  3G7G A;  2XE5 A;  3QRA A;  4IL6 O;  5DIP A;  2R8A A;  4GHB A;  3AAE B;  2CWQ A;  2PFX A;  2K4T A;  3AA1 B;  4AZL A;  3JCU O;  3BRZ A;  4GF4 A;  1ME5 A;  2ERV A;  3C1L A;  3PRN A;  4F4B A;  3POQ A;  1OSM A;  4N59 A;  1HXU A;  4FRT A;  5ADX K;  2GE4 A;  3LK3 B;  1H6S 1;  3AA6 B;  2YPV A;  3VY9 X;  3POX A;  5D5D A;  2IJC A;  2W80 C;  4FQE A;  4GCQ A;  3O0E A;  4AYN A;  1IZN A;  4C69 X;  4N58 A;  3VY8 X;  4AFK A;  1GFP A;  2PRN A;  3SZV A;  4CTD A;  3LVY A;  2X27 X;  2WVP A;  4C00 A;  3AA7 A;  1GFM A;  3T20 A;  2W81 C;  2R4L A;  2ODJ A;  3FYX A;  2M07 A;  2IWW A;  2Y7S A;  2M06 A;  2OYO A;  3SYS A;  4E1T A;  3PQS A;  3PF1 A;  3BRY A;  3LK4 2;  5B66 O;  2R89 A;  3TZG A;  5AFU K;  5E79 O;  3AA6 A;  2XE3 A;  3LK2 B;  3HWB A;  3WU2 O;  2OUW A;  1G90 A;  5H2F O;  2R88 A;  4FOZ A;  1ZHW A;  3VE1 A;  2LHF A;  1PRN A;  1P8C A;  4RLB A;  4AUI A;  3D7I A;  2XTQ A;  4LSF A;  3GP6 A;  2LFU A;  4FZN A;  4N75 A;  4FMS A;  2ES9 A;  4PJ0 O;  3AAA B;  5KAF O;  3A0B O;  3HOE A;  1MM5 A;  1S5L O;  5G26 A;  3NSG A;  1VKE A;  2Y0L A;  2AF7 A;  4O3W A;  3PQU A;  3SY7 A;  3SYB A;  3DA4 A;  3POU A;  2Y0K A;  3HOL A;  2N2L A;  5DIK A;  5G39 A;  2QTK A;  3C5O A;  1MPF A;  2KXP B;  3DWO X;  3K19 A;  1THQ A;  2O4V A;  3UAQ A;  1GFN A;  5FVN A;  2QEU A;  4JCH A;  4B61 A;  2XMX A;  2JMM A;  1QJ8 A;  3AA0 B;  4XNK A;  4RLC A;  1HXT A;  4FZL A;  3AAE A;  5JDP A;  5AFU L;  3AA1 A;  2O4D A;  1KNC A;  1BT9 A;  2F1C X;  1P4T A;  7PRN A;  4U9C A;  4O4U A;  4PR7 A;  4D64 A;  2Y0H A;  3A2S X;  4AKM A;  1OPF A;  3QRC A;  2KXP A;  4O3X B;  3LK3 A;  1T16 A;  3KVD D;  3SY9 A;  3BEY A;  3VZU X;  4RL9 A;  4UB6 O;  1YS5 A;  2Y2X A;  4FT6 A;  3DZM A;  4XNL A;  4C4V B;  3HW9 A;  4FES A;  4LSE A;  4LSH A;  4RJX A;  3AA0 A;  4FUV A;  2K0L A;  4LSI A;  1BXW A;  2OMF A;  4O49 A;  2FGQ X;  2R4P A;  2FGR A;  1QJP A;  4N74 A;  2XG6 A;  3UU2 A;  1Q9G A;  3SZD A;  4G75 A;  5KAI O;  3NJT A;  4FZM A;  5PRN A;  4FSO A;  5EE2 A;  4AYE C;  4RJW A;  1QJ9 A;  2XE2 A;  3T24 A;  3WI4 A;  4PUX A;  5TIS O;  2J1N A;  5ADX L;  1ZHZ A;  4BUM X;  3BS0 A;  1IZN B;  1LW1 A;  1ZHT A;  3LK2 A;  4KR8 A;  5IYU A;  2KZ7 B;  5DL8 A;  4C4V A;  3VZW X;  4AYD C;  3AA7 B;  3VE2 A;  4GCS A;  6PRN A;  1T1L A;  4KRA A;  1ZHX A;  2KDY A;  2F1T A;  4O3Z A;  1E54 A;  4E1S A;  5GTH O;  3AAA A;  2GMY A;  3POR A;  5GTI O;  2J4U P;  5G38 A;  2POR A;  4AYI D;  2JN8 A;  3PGS A;  3V8U A;  2WJR A;  3KZI O;  3UPG A;  4FRX A;  4AKR B;  3DA3 A;  1MM4 A;  2N2M A;  2ZFG A;  4K3B A;  1ZHY A;  2PRR A;  4JFB A;  2ZLD A;  3EMN X;  2XTR A;  5DL5 A;  2KZ7 A;  1HXX A;  4QQ1 A;  2AXT O;  2XE1 A;  2MNH A;  2WJQ A;  4Z3T A;  1PHO A;  2Q0T A;  2KC0 A;  2X9K A;  4G9Q A;  4AYM C; 
#chains in the Genus database with same CATH homology
 4O3W A;  3UU2 A;  1Q9G A;  2W80 C;  3PQU A;  4G75 A;  4GCQ A;  3SZD A;  3LK4 1;  3VZT X;  3O0E A;  4FZM A;  5PRN A;  5T5F A;  3SY7 A;  1IZN A;  3SYB A;  3DA4 A;  3POU A;  4AYN A;  4C69 X;  5DL7 A;  4D5U A;  2Y0K A;  4AYM C;  4FSO A;  3HOL A;  5EE2 A;  2N2L A;  4N58 A;  4RJW A;  5DIK A;  1QJ9 A;  2XE2 A;  4O4X A;  3T24 A;  3VY8 X;  3WI4 A;  1GFP A;  2QTK A;  4KR4 A;  4AFK A;  4PUX A;  2PRN A;  3C5O A;  2J1N A;  3SZV A;  1MPF A;  4O3Y A;  2KXP B;  3RBH A;  1Q9F A;  3LVY A;  2X27 X;  5ADX L;  1ZHZ A;  3K19 A;  4BUM X;  3WI5 A;  4AKR A;  1THQ A;  2O4V A;  3UAQ A;  3AA7 A;  2YNK A;  1GFM A;  1IZN B;  1LW1 A;  3T20 A;  2W81 C;  1GFN A;  1ZHT A;  5FVN A;  2ODJ A;  2QEU A;  4GCP A;  3FYX A;  4JCH A;  2M07 A;  3LK2 A;  1ORM A;  4B61 A;  4KR8 A;  5IYU A;  2KZ7 B;  2XMX A;  2Y7S A;  2JMM A;  2M06 A;  1QJ8 A;  3JTY A;  4FSP A;  5DL8 A;  3VZW X;  3AA0 B;  4XNK A;  4D65 A;  5DL6 A;  4RLC A;  2OYO A;  1BH3 A;  1GFQ A;  3SYS A;  8PRN A;  4E1T A;  1HXT A;  4AYE C;  3T0S A;  3PQS A;  5GV0 A;  2MHL A;  3LK4 2;  4FZL A;  3AA7 B;  4AYD C;  3AAE A;  3TZG A;  5AFU K;  3VE2 A;  2F1V A;  5JDP A;  1GU9 A;  4GCS A;  3AA6 A;  2XE3 A;  3AA1 A;  5AFU L;  6PRN A;  1GFO A;  2O4D A;  1KNC A;  3LK2 B;  1BT9 A;  3HWB A;  2OUW A;  3G7G A;  4G76 A;  1G90 A;  4KRA A;  1ZHX A;  1P4T A;  2KDY A;  7PRN A;  2XE5 A;  2F1T A;  4U9C A;  4FOZ A;  3QRA A;  1E54 A;  4O3Z A;  4E1S A;  1ZHW A;  4O4U A;  3VE1 A;  3AAA A;  5DIP A;  2LHF A;  2GMY A;  4D64 A;  1PRN A;  3POR A;  1P8C A;  2J4U P;  2Y0H A;  4GHB A;  3A2S X;  4RLB A;  4AUI A;  3D7I A;  4AKM A;  2POR A;  3AAE B;  2CWQ A;  2XTQ A;  2JN8 A;  4AYI D;  4LSF A;  1OPF A;  3V8U A;  2PFX A;  2K4T A;  3UPG A;  4FRX A;  4AKR B;  3GP6 A;  3AA1 B;  4AZL A;  3DA3 A;  3QRC A;  2KXP A;  2LFU A;  4O3X B;  3LK3 A;  4FZN A;  3KVD D;  3SY9 A;  3BEY A;  3VZU X;  1MM4 A;  4GF4 A;  1ME5 A;  4RL9 A;  1YS5 A;  5D5D A;  4FMS A;  2Y2X A;  2ES9 A;  2N2M A;  2ERV A;  3C1L A;  4FT6 A;  2ZFG A;  3AAA B;  3PRN A;  4F4B A;  1ZHY A;  4XNL A;  2PRR A;  4JFB A;  3HOE A;  2ZLD A;  3HW9 A;  3EMN X;  3POQ A;  1MM5 A;  2XTR A;  5DL5 A;  2KZ7 A;  1HXX A;  4FES A;  1OSM A;  2XE1 A;  4QQ1 A;  4N59 A;  5G26 A;  1HXU A;  2MNH A;  4LSE A;  4LSH A;  3NSG A;  4RJX A;  3AA0 A;  4FRT A;  4FUV A;  5ADX K;  4Z3T A;  2K0L A;  4LSI A;  2GE4 A;  1VKE A;  1BXW A;  2OMF A;  3LK3 B;  4O49 A;  1PHO A;  1H6S 1;  2Q0T A;  2FGQ X;  2KC0 A;  3AA6 B;  2YPV A;  3VY9 X;  4G9Q A;  2FGR A;  1QJP A;  2Y0L A;  2XG6 A;  3POX A;  2AF7 A;  2IJC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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