3LK41

Crystal structure of capz bound to the uncapping motif from cd2ap
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
269
structure length
269
Chain Sequence
VSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural characterization of a capping protein interaction motif defines a family of actin filament regulators
doi rcsb
molecule tags Protein binding
source organism Gallus gallus
molecule keywords F-actin-capping protein subunit alpha-1
total genus 85
structure length 269
sequence length 269
chains with identical sequence 4, 7, A, D, G, J, M, P, S, V, Y
ec nomenclature
pdb deposition date 2010-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
1 PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 3lk4101
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 3lk4102
4AKRB 4AKRA 2KXPB 1IZNB 2KXPA 1IZNA 5AFUK 3AA0B 3AA0A 3AA7B 3AA7A 2KZ7B 2KZ7A 3AA6B 3AA6A 3AAEB 3AAEA 3LK3B 3LK3A 3LK42 3AA1B 5ADXL 3AA1A 3LK41 5AFUL 5ADXK 3LK2B 3AAAB 3LK2A 3AAAA
chains in the Genus database with same CATH superfamily
2XE2A 2QTKA 3PQUA 3HWBA 3T0SA 1QJ9A 4AKMA 3AA7A 2KZ7B 3DWOX 3O0EA 5D5DA 4AZLA 2WJRA 3AA1B 5ADXL 1GFQA 2XTRA 3K19A 4RLBA 3C5OA 4B61A 3WI5A 2R4LA 4LSEA 4JFBA 4AKRA 3WU2O 1VKEA 3AA0A 4KR4A 3T24A 3UPGA 3EMNX 2MHLA 3DA3A 4FSPA 5ADXK 4D65A 1Q9GA 3HW9A 2IJCA 4AFKA 4O49A 2XE5A 5G39A 2R8AA 3LK3A 2WJQA 3VZUX 5AFUL 4BUMX 4O3YA 4N75A 4FUVA 3SY7A 3V8UA 2KXPA 4U9CA 4K3BA 2R88A 2R4PA 3AAEA 2O4VA 3NJTA 3LK42 3LVYA 3PGRA 3D7IA 5DL8A 3PF1A 2Y0KA 4C4VA 2J4UP 5DIKA 2W80C 4FZNA 3SYSA 3QRAA 4IL6O 3DA4A 2ES9A 4GCPA 3PORA 4FRXA 3RBHA 1HXTA 4LSFA 4FT6A 2PFXA 2R4NA 2ERVA 4FQEA 2X27X 4G76A 7PRNA 4KR8A 3AA6B 8PRNA 2PORA 2CWQA 3A0HO 4XNLA 3KVDD 4AYMC 4FZLA 2FGRA 3LK2B 2R4OA 2KDYA 2W81C 3AAAA 5GTIO 3VE2A 2R89A 5B66O 5TISO 4D64A 1P4TA 4F4BA 4XNKA 5G38A 1HXXA 2IWWA 3VY9X 4LSIA 2JMMA 6PRNA 2PRRA 2N2MA 1BH3A 2LFUA 4RLCA 2K4TA 4PUXA 4C00A 2OUWA 3AA7B 4C69X 5E79O 4FZMA 4AYID 3NSGA 2Y0HA 3POUA 5DIPA 3WI4A 1MM5A 4LSHA 5FVNA 4GF4A 4CTDA 2JN8A 4O4UA 4AKRB 1ZHYA 4GCQA 4UB8O 3PGUA 3SY9A 1IZNA 3AA0B 4O4XA 2M06A 1GFPA 3C1LA 2AXTO 3JTYA 5EE2A 2Q0TA 1ZHXA 4RJXA 1YS5A 3UAQA 5KAIO 3VZWX 2OYOA 3VY8X 4N58A 5AFUK 1HXUA 2MNHA 2KZ7A 2F1TA 4AYNA 2LHFA 3SZDA 4AYEC 3JCUO 3LK3B 1S5LO 1BXWA 5DL5A 3AA1A 1GFMA 2JQYA 3POXA 3SYBA 2YNKA 4RJWA 2OMFA 1P8CA 2KXPB 1MPFA 3POQA 3DWNA 2N2LA 4E1TA 1T16A 1ZHWA 3AAEB 1PHOA 1H6S1 4D5UA 2X9KA 1THQA 5DL7A 4C4VB 1ME5A 3BEYA 4QQ1A 3VZTX 5JDPA 1ZHTA 4FRTA 4UB6O 3A0BO 4AYDC 5GTHO 3KZIO 1Q9FA 1GFOA 4G9QA 3PGSA 1GU9A 1LW1A 1ZHZA 3QRCA 4FMSA 5DL6A 2M07A 5IYUA 4RL9A 5H2FO 1MM4A 3BS0A 1OSMA 4JCHA 2O4DA 3SZVA 4PR7A 2F1CX 2XG6A 3T20A 1KNCA 1QJPA 1BT9A 1GFNA 3BRZA 2F1VA 3A2SX 4GCSA 2GMYA 3AAAB 2XE3A 1PRNA 3GP6A 4FOZA 2XE1A 2Y2XA 4FSOA 2IWVA 2ODJA 2K0LA 4FESA 3TZGA 2ZFGA 3PQSA 5PRNA 2XTQA 3LK41 5T5FA 1T1LA 1E54A 2Y0LA 2QEUA 5G26A 2J1NA 2AF7A 1QJ8A 3HOLA 2KC0A 4G75A 4N74A 2ZLDA 3UU2A 3AA6A 2GE4A 2PRNA 4O3WA 2XMXA 3FYXA 4AUIA 5KAFO 4GHBA 4K3CA 1ORMA 3LK2A 3DZMA 2YPVA 4KRAA 3G7GA 4N59A 1IZNB 3PRNA 1OPFA 4Z3TA 5G3AA 3HOEA 4O3XB 2Y7SA 4PJ0O 4E1SA 4O3ZA 1G90A 5B5EO 2FGQX 3VE1A 2WVPA 3BRYA 5GV0A
chains in the Genus database with same CATH topology
2W80C 4AKRB 2XE2A 4JCHA 2O4DA 4FZNA 1ZHYA 3SZVA 3SYSA 4GCQA 2QTKA 1IZNA 3SY9A 3PQUA 3AA0B 3HWBA 3QRAA 1QJ9A 3T0SA 4O4XA 4AKMA 3AA7A 2KZ7B 2XG6A 2M06A 3DA4A 3O0EA 3T20A 5D5DA 1GFPA 2ES9A 4GCPA 3PORA 4AZLA 1KNCA 3AA1B 5ADXL 1QJPA 3C1LA 1BT9A 1GFQA 2XTRA 3K19A 4RLBA 3C5OA 3JTYA 4B61A 1GFNA 4FRXA 5EE2A 2Q0TA 3RBHA 3WI5A 1ZHXA 2F1VA 1HXTA 3A2SX 4GCSA 2GMYA 3AAAB 2XE3A 4LSFA 4RJXA 1YS5A 1PRNA 4FT6A 3GP6A 4LSEA 3UAQA 3VZWX 4FOZA 4JFBA 2OYOA 4AKRA 3VY8X 2PFXA 2XE1A 2Y2XA 4N58A 5AFUK 2ERVA 1VKEA 1HXUA 3AA0A 2X27X 4G76A 7PRNA 2MNHA 4FSOA 2ODJA 4KR8A 2KZ7A 2K0LA 2F1TA 3AA6B 4AYNA 2LHFA 8PRNA 3SZDA 4AYEC 2PORA 3LK3B 4KR4A 4FESA 3T24A 2CWQA 1BXWA 3UPGA 3TZGA 2ZFGA 5DL5A 3EMNX 3AA1A 1GFMA 4XNLA 2MHLA 3KVDD 4AYMC 4FZLA 3PQSA 5PRNA 3POXA 3SYBA 2XTQA 3LK41 5T5FA 3DA3A 2YNKA 4FSPA 2FGRA 5ADXK 3LK2B 2KDYA 2W81C 3AAAA 4RJWA 2OMFA 4D65A 1E54A 3VE2A 1P8CA 2Y0LA 2QEUA 5G26A 2J1NA 2AF7A 1Q9GA 1QJ8A 2KXPB 2IJCA 1MPFA 3HOLA 3HW9A 3POQA 2KC0A 4G75A 2N2LA 4AFKA 4E1TA 4O49A 2ZLDA 3UU2A 2XE5A 3AA6A 1ZHWA 4D64A 1P4TA 2GE4A 3AAEB 2PRNA 3LK3A 4O3WA 1PHOA 1H6S1 4D5UA 4F4BA 2XMXA 3FYXA 4XNKA 4AUIA 1HXXA 1THQA 3VZUX 5DL7A 1ME5A 3VY9X 3BEYA 4GHBA 1ORMA 4QQ1A 4BUMX 5AFUL 3VZTX 5JDPA 4O3YA 3LK2A 1ZHTA 2YPVA 4FRTA 4KRAA 4LSIA 2JMMA 4AYDC 6PRNA 2PRRA 2N2MA 4FUVA 1BH3A 2LFUA 3G7GA 4N59A 4RLCA 1Q9FA 3SY7A 1GFOA 1IZNB 2K4TA 3PRNA 2KXPA 4PUXA 3V8UA 4G9QA 4U9CA 1GU9A 2OUWA 1LW1A 1OPFA 3AA7B 4Z3TA 3HOEA 4O3XB 2Y7SA 4C69X 3AAEA 1ZHZA 2O4VA 3QRCA 4FMSA 4FZMA 5DL6A 4E1SA 4AYID 3LK42 3NSGA 4O3ZA 2Y0HA 3POUA 3LVYA 5DIPA 1G90A 3WI4A 3D7IA 2FGQX 2M07A 5DL8A 3VE1A 4RL9A 5IYUA 1MM5A 2Y0KA 1MM4A 4LSHA 5FVNA 2J4UP 4GF4A 5DIKA 2JN8A 5GV0A 4O4UA 1OSMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AKR B;  4AKR A;  2KXP B;  1IZN B;  2KXP A;  1IZN A;  5AFU K;  3AA0 B;  3AA0 A;  3AA7 B;  3AA7 A;  2KZ7 B;  2KZ7 A;  3AA6 B;  3AA6 A;  3AAE B;  3AAE A;  3LK3 B;  3LK3 A;  3LK4 2;  3AA1 B;  5ADX L;  3AA1 A;  3LK4 1;  5AFU L;  5ADX K;  3LK2 B;  3AAA B;  3LK2 A;  3AAA A; 
#chains in the Genus database with same CATH topology
 2XE2 A;  2QTK A;  3PQU A;  3HWB A;  3T0S A;  1QJ9 A;  4AKM A;  3AA7 A;  2KZ7 B;  3DWO X;  3O0E A;  5D5D A;  4AZL A;  2WJR A;  3AA1 B;  5ADX L;  1GFQ A;  2XTR A;  3K19 A;  4RLB A;  3C5O A;  4B61 A;  3WI5 A;  2R4L A;  4LSE A;  4JFB A;  4AKR A;  3WU2 O;  1VKE A;  3AA0 A;  4KR4 A;  3T24 A;  3UPG A;  3EMN X;  2MHL A;  3DA3 A;  4FSP A;  5ADX K;  4D65 A;  1Q9G A;  3HW9 A;  2IJC A;  4AFK A;  4O49 A;  2XE5 A;  5G39 A;  2R8A A;  3LK3 A;  2WJQ A;  3VZU X;  5AFU L;  4BUM X;  4O3Y A;  4N75 A;  4FUV A;  3SY7 A;  3V8U A;  2KXP A;  4U9C A;  4K3B A;  2R88 A;  2R4P A;  3AAE A;  2O4V A;  3NJT A;  3LK4 2;  3LVY A;  3PGR A;  3D7I A;  5DL8 A;  3PF1 A;  2Y0K A;  4C4V A;  2J4U P;  5DIK A;  2W80 C;  4FZN A;  3SYS A;  3QRA A;  4IL6 O;  3DA4 A;  2ES9 A;  4GCP A;  3POR A;  4FRX A;  3RBH A;  1HXT A;  4LSF A;  4FT6 A;  2PFX A;  2R4N A;  2ERV A;  4FQE A;  2X27 X;  4G76 A;  7PRN A;  4KR8 A;  3AA6 B;  8PRN A;  2POR A;  2CWQ A;  3A0H O;  4XNL A;  3KVD D;  4AYM C;  4FZL A;  2FGR A;  3LK2 B;  2R4O A;  2KDY A;  2W81 C;  3AAA A;  5GTI O;  3VE2 A;  2R89 A;  5B66 O;  5TIS O;  4D64 A;  1P4T A;  4F4B A;  4XNK A;  5G38 A;  1HXX A;  2IWW A;  3VY9 X;  4LSI A;  2JMM A;  6PRN A;  2PRR A;  2N2M A;  1BH3 A;  2LFU A;  4RLC A;  2K4T A;  4PUX A;  4C00 A;  2OUW A;  3AA7 B;  4C69 X;  5E79 O;  4FZM A;  4AYI D;  3NSG A;  2Y0H A;  3POU A;  5DIP A;  3WI4 A;  1MM5 A;  4LSH A;  5FVN A;  4GF4 A;  4CTD A;  2JN8 A;  4O4U A;  4AKR B;  1ZHY A;  4GCQ A;  4UB8 O;  3PGU A;  3SY9 A;  1IZN A;  3AA0 B;  4O4X A;  2M06 A;  1GFP A;  3C1L A;  2AXT O;  3JTY A;  5EE2 A;  2Q0T A;  1ZHX A;  4RJX A;  1YS5 A;  3UAQ A;  5KAI O;  3VZW X;  2OYO A;  3VY8 X;  4N58 A;  5AFU K;  1HXU A;  2MNH A;  2KZ7 A;  2F1T A;  4AYN A;  2LHF A;  3SZD A;  4AYE C;  3JCU O;  3LK3 B;  1S5L O;  1BXW A;  5DL5 A;  3AA1 A;  1GFM A;  2JQY A;  3POX A;  3SYB A;  2YNK A;  4RJW A;  2OMF A;  1P8C A;  2KXP B;  1MPF A;  3POQ A;  3DWN A;  2N2L A;  4E1T A;  1T16 A;  1ZHW A;  3AAE B;  1PHO A;  1H6S 1;  4D5U A;  2X9K A;  1THQ A;  5DL7 A;  4C4V B;  1ME5 A;  3BEY A;  4QQ1 A;  3VZT X;  5JDP A;  1ZHT A;  4FRT A;  4UB6 O;  3A0B O;  4AYD C;  5GTH O;  3KZI O;  1Q9F A;  1GFO A;  4G9Q A;  3PGS A;  1GU9 A;  1LW1 A;  1ZHZ A;  3QRC A;  4FMS A;  5DL6 A;  2M07 A;  5IYU A;  4RL9 A;  5H2F O;  1MM4 A;  3BS0 A;  1OSM A;  4JCH A;  2O4D A;  3SZV A;  4PR7 A;  2F1C X;  2XG6 A;  3T20 A;  1KNC A;  1QJP A;  1BT9 A;  1GFN A;  3BRZ A;  2F1V A;  3A2S X;  4GCS A;  2GMY A;  3AAA B;  2XE3 A;  1PRN A;  3GP6 A;  4FOZ A;  2XE1 A;  2Y2X A;  4FSO A;  2IWV A;  2ODJ A;  2K0L A;  4FES A;  3TZG A;  2ZFG A;  3PQS A;  5PRN A;  2XTQ A;  3LK4 1;  5T5F A;  1T1L A;  1E54 A;  2Y0L A;  2QEU A;  5G26 A;  2J1N A;  2AF7 A;  1QJ8 A;  3HOL A;  2KC0 A;  4G75 A;  4N74 A;  2ZLD A;  3UU2 A;  3AA6 A;  2GE4 A;  2PRN A;  4O3W A;  2XMX A;  3FYX A;  4AUI A;  5KAF O;  4GHB A;  4K3C A;  1ORM A;  3LK2 A;  3DZM A;  2YPV A;  4KRA A;  3G7G A;  4N59 A;  1IZN B;  3PRN A;  1OPF A;  4Z3T A;  5G3A A;  3HOE A;  4O3X B;  2Y7S A;  4PJ0 O;  4E1S A;  4O3Z A;  1G90 A;  5B5E O;  2FGQ X;  3VE1 A;  2WVP A;  3BRY A;  5GV0 A; 
#chains in the Genus database with same CATH homology
 2W80 C;  4AKR B;  2XE2 A;  4JCH A;  2O4D A;  4FZN A;  1ZHY A;  3SZV A;  3SYS A;  4GCQ A;  2QTK A;  1IZN A;  3SY9 A;  3PQU A;  3AA0 B;  3HWB A;  3QRA A;  1QJ9 A;  3T0S A;  4O4X A;  4AKM A;  3AA7 A;  2KZ7 B;  2XG6 A;  2M06 A;  3DA4 A;  3O0E A;  3T20 A;  5D5D A;  1GFP A;  2ES9 A;  4GCP A;  3POR A;  4AZL A;  1KNC A;  3AA1 B;  5ADX L;  1QJP A;  3C1L A;  1BT9 A;  1GFQ A;  2XTR A;  3K19 A;  4RLB A;  3C5O A;  3JTY A;  4B61 A;  1GFN A;  4FRX A;  5EE2 A;  2Q0T A;  3RBH A;  3WI5 A;  1ZHX A;  2F1V A;  1HXT A;  3A2S X;  4GCS A;  2GMY A;  3AAA B;  2XE3 A;  4LSF A;  4RJX A;  1YS5 A;  1PRN A;  4FT6 A;  3GP6 A;  4LSE A;  3UAQ A;  3VZW X;  4FOZ A;  4JFB A;  2OYO A;  4AKR A;  3VY8 X;  2PFX A;  2XE1 A;  2Y2X A;  4N58 A;  5AFU K;  2ERV A;  1VKE A;  1HXU A;  3AA0 A;  2X27 X;  4G76 A;  7PRN A;  2MNH A;  4FSO A;  2ODJ A;  4KR8 A;  2KZ7 A;  2K0L A;  2F1T A;  3AA6 B;  4AYN A;  2LHF A;  8PRN A;  3SZD A;  4AYE C;  2POR A;  3LK3 B;  4KR4 A;  4FES A;  3T24 A;  2CWQ A;  1BXW A;  3UPG A;  3TZG A;  2ZFG A;  5DL5 A;  3EMN X;  3AA1 A;  1GFM A;  4XNL A;  2MHL A;  3KVD D;  4AYM C;  4FZL A;  3PQS A;  5PRN A;  3POX A;  3SYB A;  2XTQ A;  3LK4 1;  5T5F A;  3DA3 A;  2YNK A;  4FSP A;  2FGR A;  5ADX K;  3LK2 B;  2KDY A;  2W81 C;  3AAA A;  4RJW A;  2OMF A;  4D65 A;  1E54 A;  3VE2 A;  1P8C A;  2Y0L A;  2QEU A;  5G26 A;  2J1N A;  2AF7 A;  1Q9G A;  1QJ8 A;  2KXP B;  2IJC A;  1MPF A;  3HOL A;  3HW9 A;  3POQ A;  2KC0 A;  4G75 A;  2N2L A;  4AFK A;  4E1T A;  4O49 A;  2ZLD A;  3UU2 A;  2XE5 A;  3AA6 A;  1ZHW A;  4D64 A;  1P4T A;  2GE4 A;  3AAE B;  2PRN A;  3LK3 A;  4O3W A;  1PHO A;  1H6S 1;  4D5U A;  4F4B A;  2XMX A;  3FYX A;  4XNK A;  4AUI A;  1HXX A;  1THQ A;  3VZU X;  5DL7 A;  1ME5 A;  3VY9 X;  3BEY A;  4GHB A;  1ORM A;  4QQ1 A;  4BUM X;  5AFU L;  3VZT X;  5JDP A;  4O3Y A;  3LK2 A;  1ZHT A;  2YPV A;  4FRT A;  4KRA A;  4LSI A;  2JMM A;  4AYD C;  6PRN A;  2PRR A;  2N2M A;  4FUV A;  1BH3 A;  2LFU A;  3G7G A;  4N59 A;  4RLC A;  1Q9F A;  3SY7 A;  1GFO A;  1IZN B;  2K4T A;  3PRN A;  2KXP A;  4PUX A;  3V8U A;  4G9Q A;  4U9C A;  1GU9 A;  2OUW A;  1LW1 A;  1OPF A;  3AA7 B;  4Z3T A;  3HOE A;  4O3X B;  2Y7S A;  4C69 X;  3AAE A;  1ZHZ A;  2O4V A;  3QRC A;  4FMS A;  4FZM A;  5DL6 A;  4E1S A;  4AYI D;  3LK4 2;  3NSG A;  4O3Z A;  2Y0H A;  3POU A;  3LVY A;  5DIP A;  1G90 A;  3WI4 A;  3D7I A;  2FGQ X;  2M07 A;  5DL8 A;  3VE1 A;  4RL9 A;  5IYU A;  1MM5 A;  2Y0K A;  1MM4 A;  4LSH A;  5FVN A;  2J4U P;  4GF4 A;  5DIK A;  2JN8 A;  5GV0 A;  4O4U A;  1OSM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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