3LK41

Crystal structure of capz bound to the uncapping motif from cd2ap
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
269
structure length
269
Chain Sequence
VSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural characterization of a capping protein interaction motif defines a family of actin filament regulators
doi rcsb
molecule tags Protein binding
source organism Gallus gallus
molecule keywords F-actin-capping protein subunit alpha-1
total genus 85
structure length 269
sequence length 269
chains with identical sequence 4, 7, A, D, G, J, M, P, S, V, Y
ec nomenclature
pdb deposition date 2010-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
1 PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 3lk4101
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 3lk4102
3LK2A 3LK3A 3AA7A 3AA0B 3AA1A 3LK41 4AKRA 1IZNB 2KXPB 3AAAB 5AFUK 5AFUL 3LK3B 2KZ7A 3LK2B 5ADXK 3AA7B 3AA1B 4AKRB 5ADXL 3AA6A 3LK42 3AAEA 2KZ7B 3AA0A 1IZNA 3AA6B 2KXPA 3AAAA 3AAEB
chains in the Genus database with same CATH superfamily
2W80C 4G9QA 2KZ7A 4FESA 4K3BA 1ORMA 4UB8O 4XNKA 4LSIA 5GV0A 5G38A 3WI5A 1P8CA 3AA6B 2M06A 4O3ZA 3BRYA 2QTKA 1ME5A 3DA4A 4O4UA 5PRNA 1T16A 3LK3A 1P4TA 5GTHO 1GFQA 5G26A 3AA6A 3BS0A 1HXTA 2IWWA 4E1TA 3A0BO 4AYID 4RLBA 5DIKA 4O3XB 2WVPA 2AXTO 3AA7B 3PQSA 1YS5A 4FZMA 4XNLA 3DZMA 4AZLA 4FUVA 4FZLA 4RLCA 4KR8A 2MNHA 3AAEB 4FOZA 3AA7A 2WJRA 3G7GA 2R4OA 3HWBA 1QJ8A 2XMXA 2PORA 3PQUA 3AAEA 1QJPA 4PUXA 2XE5A 4FZNA 3QRCA 2IWVA 4F4BA 4G76A 2KXPB 2QEUA 2XE3A 2ODJA 2OMFA 4O4XA 4KRAA 4LSHA 2X9KA 2N2MA 4PR7A 2KXPA 4AYEC 2J1NA 4N58A 2ZFGA 1VKEA 5B66O 3BRZA 3HOEA 5G39A 3LK2B 3UU2A 4E1SA 4UB6O 7PRNA 4D65A 1ZHYA 4GCQA 4B61A 4N75A 2J4UP 4FRTA 2N2LA 4D5UA 3T0SA 3LK2A 2XE1A 1PHOA 2KC0A 3DA3A 4BUMX 1QJ9A 3AA1B 3UPGA 4AYMC 3PORA 5GTIO 2GE4A 4O3YA 2K4TA 4GF4A 2YNKA 1LW1A 3PGSA 2JN8A 4FSOA 4N59A 3AA1A 2MHLA 3WU2O 4GCPA 3C5OA 4GCSA 1OSMA 2CWQA 2Y7SA 2YPVA 2AF7A 2WJQA 4FQEA 4FRXA 3NSGA 3A0HO 3BEYA 1S5LO 4C69X 5KAFO 1MPFA 4AYDC 2R4NA 3WI4A 3EMNX 3KVDD 4RJXA 2PRRA 2ERVA 1GFNA 3SYSA 1GFPA 4CTDA 5FVNA 4FMSA 3NJTA 3POQA 1Q9FA 1IZNB 2XTQA 2GMYA 3AAAB 1H6S1 3T20A 1BT9A 5ADXK 5ADXL 3KZIO 2Y0LA 3V8UA 3LK42 2K0LA 5IYUA 3SY7A 3JTYA 1IZNA 2R89A 4AFKA 3AAAA 2Y2XA 3VZWX 2KDYA 4AUIA 3QRAA 3AA0B 2XE2A 2JQYA 3POUA 4U9CA 2OYOA 2LFUA 3SYBA 2PFXA 3AA0A 2LHFA 2XTRA 4D64A 3A2SX 4RJWA 2FGRA 1GFOA 2OUWA 3LK3B 5B5EO 2F1TA 1KNCA 3VY8X 4N74A 1BH3A 3DWNA 3PF1A 4PJ0O 2O4VA 1THQA 2JMMA 2R4LA 1G90A 2Y0HA 1ZHTA 4C00A 1MM5A 3VZUX 2X27X 4FSPA 3DWOX 1MM4A 1HXUA 3D7IA 4LSEA 2R88A 5DL8A 1GU9A 3LVYA 4C4VB 1ZHWA 3RBHA 2R4PA 3O0EA 5T5FA 3PGRA 1Q9GA 4AKMA 5TISO 3SY9A 3SZDA 1BXWA 1T1LA 4KR4A 2ES9A 3VZTX 3HOLA 5DL6A 3HW9A 2ZLDA 3VY9X 4C4VA 2F1VA 4IL6O 4LSFA 5JDPA 5H2FO 4O3WA 6PRNA 1E54A 1GFMA 4FT6A 3K19A 2R8AA 5E79O 3VE2A 1ZHZA 4JFBA 1HXXA 4K3CA 3GP6A 1ZHXA 3POXA 4JCHA 1PRNA 2O4DA 4AKRB 3PGUA 2FGQX 2IJCA 8PRNA 1OPFA 4Z3TA 5DL5A 5EE2A 4AYNA 5DL7A 4QQ1A 3UAQA 2M07A 2W81C 3LK41 4AKRA 2PRNA 5AFUK 5G3AA 2XG6A 5KAIO 5AFUL 4O49A 3FYXA 3T24A 3TZGA 2Y0KA 3SZVA 4G75A 2KZ7B 3JCUO 5DIPA 4GHBA 4RL9A 2F1CX 3PRNA 3VE1A 3C1LA 2Q0TA 5D5DA
chains in the Genus database with same CATH topology
2W80C 3NSGA 2X27X 4FSPA 1MM4A 3BEYA 2KXPB 4G9QA 4C69X 1HXUA 1MPFA 2QEUA 3D7IA 4AYDC 2KZ7A 4LSEA 2XE3A 3WI4A 3EMNX 2ODJA 3KVDD 4FESA 4RJXA 2PRRA 2OMFA 2ERVA 1GFNA 1ORMA 5DL8A 1GU9A 4O4XA 4KRAA 3SYSA 3LVYA 4LSHA 4XNKA 1ZHWA 4LSIA 3RBHA 5GV0A 3WI5A 1P8CA 2N2MA 3AA6B 3O0EA 5T5FA 2KXPA 2M06A 1GFPA 1Q9GA 4O3ZA 4AKMA 4AYEC 2QTKA 5FVNA 3SY9A 3SZDA 1BXWA 1ME5A 2J1NA 3DA4A 4FMSA 4N58A 4O4UA 5PRNA 3POQA 3LK3A 1Q9FA 4KR4A 2ES9A 3VZTX 1IZNB 1P4TA 2XTQA 3HOLA 2ZFGA 1VKEA 5DL6A 3HW9A 1GFQA 2GMYA 5G26A 3AAAB 1H6S1 3HOEA 2ZLDA 3VY9X 3T20A 3LK2B 3UU2A 1BT9A 5ADXK 4E1SA 2F1VA 5ADXL 3AA6A 1HXTA 2Y0LA 4LSFA 5JDPA 7PRNA 3V8UA 1ZHYA 3LK42 4D65A 4GCQA 2K0LA 5IYUA 4B61A 4O3WA 3SY7A 6PRNA 2J4UP 1E54A 3JTYA 4FRTA 4E1TA 1IZNA 1GFMA 2N2LA 4FT6A 3K19A 4AFKA 4D5UA 3VE2A 3AAAA 3T0SA 1ZHZA 2Y2XA 4JFBA 3VZWX 4AYID 1HXXA 4RLBA 3LK2A 5DIKA 2KDYA 3GP6A 3QRAA 3AA0B 2XE2A 4AUIA 2XE1A 1ZHXA 4O3XB 1PHOA 3POXA 2KC0A 4JCHA 3DA3A 3POUA 4U9CA 1PRNA 4BUMX 2O4DA 1QJ9A 3AA7B 3AA1B 4AKRB 3UPGA 3PQSA 4AYMC 1YS5A 2FGQX 3PORA 4FZMA 4XNLA 2IJCA 2GE4A 1OPFA 8PRNA 4O3YA 4AZLA 2OYOA 4FUVA 2K4TA 2LFUA 4FZLA 4Z3TA 3SYBA 2PFXA 4GF4A 5DL5A 3AA0A 2LHFA 2YNKA 4RLCA 2XTRA 4KR8A 1LW1A 5EE2A 3A2SX 4AYNA 4D64A 5DL7A 4QQ1A 4RJWA 2FGRA 1GFOA 2MNHA 2JN8A 3UAQA 2M07A 3AAEB 4FSOA 4FOZA 4N59A 2W81C 3AA7A 3AA1A 3LK41 2OUWA 4AKRA 2MHLA 3G7GA 3HWBA 2PRNA 5AFUK 1QJ8A 2XG6A 5AFUL 4O49A 3FYXA 3LK3B 4GCPA 3C5OA 3T24A 3TZGA 2XMXA 4GCSA 2PORA 2F1TA 1KNCA 3VY8X 1OSMA 2Y0KA 3SZVA 4G75A 2CWQA 1BH3A 3PQUA 3AAEA 1QJPA 2KZ7B 2XE5A 4PUXA 2Y7SA 2YPVA 4FZNA 2AF7A 3QRCA 5DIPA 4GHBA 2O4VA 4RL9A 3PRNA 1THQA 2JMMA 3VE1A 1G90A 3C1LA 2Y0HA 1ZHTA 4G76A 2Q0TA 4F4BA 1MM5A 3VZUX 5D5DA 4FRXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LK2 A;  3LK3 A;  3AA7 A;  3AA0 B;  3AA1 A;  3LK4 1;  4AKR A;  1IZN B;  2KXP B;  3AAA B;  5AFU K;  5AFU L;  3LK3 B;  2KZ7 A;  3LK2 B;  5ADX K;  3AA7 B;  3AA1 B;  4AKR B;  5ADX L;  3AA6 A;  3LK4 2;  3AAE A;  2KZ7 B;  3AA0 A;  1IZN A;  3AA6 B;  2KXP A;  3AAA A;  3AAE B; 
#chains in the Genus database with same CATH topology
 2W80 C;  4G9Q A;  2KZ7 A;  4FES A;  4K3B A;  1ORM A;  4UB8 O;  4XNK A;  4LSI A;  5GV0 A;  5G38 A;  3WI5 A;  1P8C A;  3AA6 B;  2M06 A;  4O3Z A;  3BRY A;  2QTK A;  1ME5 A;  3DA4 A;  4O4U A;  5PRN A;  1T16 A;  3LK3 A;  1P4T A;  5GTH O;  1GFQ A;  5G26 A;  3AA6 A;  3BS0 A;  1HXT A;  2IWW A;  4E1T A;  3A0B O;  4AYI D;  4RLB A;  5DIK A;  4O3X B;  2WVP A;  2AXT O;  3AA7 B;  3PQS A;  1YS5 A;  4FZM A;  4XNL A;  3DZM A;  4AZL A;  4FUV A;  4FZL A;  4RLC A;  4KR8 A;  2MNH A;  3AAE B;  4FOZ A;  3AA7 A;  2WJR A;  3G7G A;  2R4O A;  3HWB A;  1QJ8 A;  2XMX A;  2POR A;  3PQU A;  3AAE A;  1QJP A;  4PUX A;  2XE5 A;  4FZN A;  3QRC A;  2IWV A;  4F4B A;  4G76 A;  2KXP B;  2QEU A;  2XE3 A;  2ODJ A;  2OMF A;  4O4X A;  4KRA A;  4LSH A;  2X9K A;  2N2M A;  4PR7 A;  2KXP A;  4AYE C;  2J1N A;  4N58 A;  2ZFG A;  1VKE A;  5B66 O;  3BRZ A;  3HOE A;  5G39 A;  3LK2 B;  3UU2 A;  4E1S A;  4UB6 O;  7PRN A;  4D65 A;  1ZHY A;  4GCQ A;  4B61 A;  4N75 A;  2J4U P;  4FRT A;  2N2L A;  4D5U A;  3T0S A;  3LK2 A;  2XE1 A;  1PHO A;  2KC0 A;  3DA3 A;  4BUM X;  1QJ9 A;  3AA1 B;  3UPG A;  4AYM C;  3POR A;  5GTI O;  2GE4 A;  4O3Y A;  2K4T A;  4GF4 A;  2YNK A;  1LW1 A;  3PGS A;  2JN8 A;  4FSO A;  4N59 A;  3AA1 A;  2MHL A;  3WU2 O;  4GCP A;  3C5O A;  4GCS A;  1OSM A;  2CWQ A;  2Y7S A;  2YPV A;  2AF7 A;  2WJQ A;  4FQE A;  4FRX A;  3NSG A;  3A0H O;  3BEY A;  1S5L O;  4C69 X;  5KAF O;  1MPF A;  4AYD C;  2R4N A;  3WI4 A;  3EMN X;  3KVD D;  4RJX A;  2PRR A;  2ERV A;  1GFN A;  3SYS A;  1GFP A;  4CTD A;  5FVN A;  4FMS A;  3NJT A;  3POQ A;  1Q9F A;  1IZN B;  2XTQ A;  2GMY A;  3AAA B;  1H6S 1;  3T20 A;  1BT9 A;  5ADX K;  5ADX L;  3KZI O;  2Y0L A;  3V8U A;  3LK4 2;  2K0L A;  5IYU A;  3SY7 A;  3JTY A;  1IZN A;  2R89 A;  4AFK A;  3AAA A;  2Y2X A;  3VZW X;  2KDY A;  4AUI A;  3QRA A;  3AA0 B;  2XE2 A;  2JQY A;  3POU A;  4U9C A;  2OYO A;  2LFU A;  3SYB A;  2PFX A;  3AA0 A;  2LHF A;  2XTR A;  4D64 A;  3A2S X;  4RJW A;  2FGR A;  1GFO A;  2OUW A;  3LK3 B;  5B5E O;  2F1T A;  1KNC A;  3VY8 X;  4N74 A;  1BH3 A;  3DWN A;  3PF1 A;  4PJ0 O;  2O4V A;  1THQ A;  2JMM A;  2R4L A;  1G90 A;  2Y0H A;  1ZHT A;  4C00 A;  1MM5 A;  3VZU X;  2X27 X;  4FSP A;  3DWO X;  1MM4 A;  1HXU A;  3D7I A;  4LSE A;  2R88 A;  5DL8 A;  1GU9 A;  3LVY A;  4C4V B;  1ZHW A;  3RBH A;  2R4P A;  3O0E A;  5T5F A;  3PGR A;  1Q9G A;  4AKM A;  5TIS O;  3SY9 A;  3SZD A;  1BXW A;  1T1L A;  4KR4 A;  2ES9 A;  3VZT X;  3HOL A;  5DL6 A;  3HW9 A;  2ZLD A;  3VY9 X;  4C4V A;  2F1V A;  4IL6 O;  4LSF A;  5JDP A;  5H2F O;  4O3W A;  6PRN A;  1E54 A;  1GFM A;  4FT6 A;  3K19 A;  2R8A A;  5E79 O;  3VE2 A;  1ZHZ A;  4JFB A;  1HXX A;  4K3C A;  3GP6 A;  1ZHX A;  3POX A;  4JCH A;  1PRN A;  2O4D A;  4AKR B;  3PGU A;  2FGQ X;  2IJC A;  8PRN A;  1OPF A;  4Z3T A;  5DL5 A;  5EE2 A;  4AYN A;  5DL7 A;  4QQ1 A;  3UAQ A;  2M07 A;  2W81 C;  3LK4 1;  4AKR A;  2PRN A;  5AFU K;  5G3A A;  2XG6 A;  5KAI O;  5AFU L;  4O49 A;  3FYX A;  3T24 A;  3TZG A;  2Y0K A;  3SZV A;  4G75 A;  2KZ7 B;  3JCU O;  5DIP A;  4GHB A;  4RL9 A;  2F1C X;  3PRN A;  3VE1 A;  3C1L A;  2Q0T A;  5D5D A; 
#chains in the Genus database with same CATH homology
 2W80 C;  3NSG A;  2X27 X;  4FSP A;  1MM4 A;  3BEY A;  2KXP B;  4G9Q A;  4C69 X;  1HXU A;  1MPF A;  2QEU A;  3D7I A;  4AYD C;  2KZ7 A;  4LSE A;  2XE3 A;  3WI4 A;  3EMN X;  2ODJ A;  3KVD D;  4FES A;  4RJX A;  2PRR A;  2OMF A;  2ERV A;  1GFN A;  1ORM A;  5DL8 A;  1GU9 A;  4O4X A;  4KRA A;  3SYS A;  3LVY A;  4LSH A;  4XNK A;  1ZHW A;  4LSI A;  3RBH A;  5GV0 A;  3WI5 A;  1P8C A;  2N2M A;  3AA6 B;  3O0E A;  5T5F A;  2KXP A;  2M06 A;  1GFP A;  1Q9G A;  4O3Z A;  4AKM A;  4AYE C;  2QTK A;  5FVN A;  3SY9 A;  3SZD A;  1BXW A;  1ME5 A;  2J1N A;  3DA4 A;  4FMS A;  4N58 A;  4O4U A;  5PRN A;  3POQ A;  3LK3 A;  1Q9F A;  4KR4 A;  2ES9 A;  3VZT X;  1IZN B;  1P4T A;  2XTQ A;  3HOL A;  2ZFG A;  1VKE A;  5DL6 A;  3HW9 A;  1GFQ A;  2GMY A;  5G26 A;  3AAA B;  1H6S 1;  3HOE A;  2ZLD A;  3VY9 X;  3T20 A;  3LK2 B;  3UU2 A;  1BT9 A;  5ADX K;  4E1S A;  2F1V A;  5ADX L;  3AA6 A;  1HXT A;  2Y0L A;  4LSF A;  5JDP A;  7PRN A;  3V8U A;  1ZHY A;  3LK4 2;  4D65 A;  4GCQ A;  2K0L A;  5IYU A;  4B61 A;  4O3W A;  3SY7 A;  6PRN A;  2J4U P;  1E54 A;  3JTY A;  4FRT A;  4E1T A;  1IZN A;  1GFM A;  2N2L A;  4FT6 A;  3K19 A;  4AFK A;  4D5U A;  3VE2 A;  3AAA A;  3T0S A;  1ZHZ A;  2Y2X A;  4JFB A;  3VZW X;  4AYI D;  1HXX A;  4RLB A;  3LK2 A;  5DIK A;  2KDY A;  3GP6 A;  3QRA A;  3AA0 B;  2XE2 A;  4AUI A;  2XE1 A;  1ZHX A;  4O3X B;  1PHO A;  3POX A;  2KC0 A;  4JCH A;  3DA3 A;  3POU A;  4U9C A;  1PRN A;  4BUM X;  2O4D A;  1QJ9 A;  3AA7 B;  3AA1 B;  4AKR B;  3UPG A;  3PQS A;  4AYM C;  1YS5 A;  2FGQ X;  3POR A;  4FZM A;  4XNL A;  2IJC A;  2GE4 A;  1OPF A;  8PRN A;  4O3Y A;  4AZL A;  2OYO A;  4FUV A;  2K4T A;  2LFU A;  4FZL A;  4Z3T A;  3SYB A;  2PFX A;  4GF4 A;  5DL5 A;  3AA0 A;  2LHF A;  2YNK A;  4RLC A;  2XTR A;  4KR8 A;  1LW1 A;  5EE2 A;  3A2S X;  4AYN A;  4D64 A;  5DL7 A;  4QQ1 A;  4RJW A;  2FGR A;  1GFO A;  2MNH A;  2JN8 A;  3UAQ A;  2M07 A;  3AAE B;  4FSO A;  4FOZ A;  4N59 A;  2W81 C;  3AA7 A;  3AA1 A;  3LK4 1;  2OUW A;  4AKR A;  2MHL A;  3G7G A;  3HWB A;  2PRN A;  5AFU K;  1QJ8 A;  2XG6 A;  5AFU L;  4O49 A;  3FYX A;  3LK3 B;  4GCP A;  3C5O A;  3T24 A;  3TZG A;  2XMX A;  4GCS A;  2POR A;  2F1T A;  1KNC A;  3VY8 X;  1OSM A;  2Y0K A;  3SZV A;  4G75 A;  2CWQ A;  1BH3 A;  3PQU A;  3AAE A;  1QJP A;  2KZ7 B;  2XE5 A;  4PUX A;  2Y7S A;  2YPV A;  4FZN A;  2AF7 A;  3QRC A;  5DIP A;  4GHB A;  2O4V A;  4RL9 A;  3PRN A;  1THQ A;  2JMM A;  3VE1 A;  1G90 A;  3C1L A;  2Y0H A;  1ZHT A;  4G76 A;  2Q0T A;  4F4B A;  1MM5 A;  3VZU X;  5D5D A;  4FRX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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