3LK41

Crystal structure of capz bound to the uncapping motif from cd2ap
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
269
structure length
269
Chain Sequence
VSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYDDQVLITEHGDLGNGRFLDPRNKISFKFDHLRKEASDPQPEDTESALKQWRDACDSALRAYVKDHYPNGFCTVYGKSIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVAAVLKIQVHYYEDGNVQLVSHKDIQDSVQVSSDVQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural characterization of a capping protein interaction motif defines a family of actin filament regulators
doi rcsb
molecule tags Protein binding
source organism Gallus gallus
molecule keywords F-actin-capping protein subunit alpha-1
total genus 85
structure length 269
sequence length 269
chains with identical sequence 4, 7, A, D, G, J, M, P, S, V, Y
ec nomenclature
pdb deposition date 2010-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
1 PF01267 F-actin_cap_A F-actin capping protein alpha subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 3lk4101
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 3lk4102
5AFUL 3AAEB 3LK2A 4AKRA 2KXPB 5ADXK 3AA1A 1IZNA 3AA0A 5ADXL 3AAEA 3AAAB 2KXPA 3AA6B 3LK3B 3LK42 3AAAA 3LK3A 2KZ7B 3AA6A 3LK41 3AA7B 3LK2B 2KZ7A 4AKRB 1IZNB 3AA7A 5AFUK 3AA1B 3AA0B
chains in the Genus database with same CATH superfamily
5FVNA 4LSEA 7PRNA 2ZLDA 3A2SX 2XE1A 2ODJA 2N2LA 2XE3A 1LW1A 4FT6A 4N75A 2OYOA 4G9QA 1GFPA 1OSMA 3UPGA 4GF4A 2PRRA 2W80C 4FZNA 3LVYA 3V8UA 3AA0B 2GE4A 2Y7SA 5ADXK 3QRCA 1Q9FA 4AKMA 2N2MA 4QQ1A 5T5FA 4RL9A 3VY8X 2XTRA 3JCUO 4RLBA 1GFQA 1ZHXA 2R89A 4C4VB 4D65A 1S5LO 3SZVA 4C69X 3NJTA 4O4UA 3AA7A 5AFUL 3RBHA 2JN8A 4AKRA 5JDPA 3BEYA 3SY9A 2R88A 2OMFA 3DA4A 1P4TA 5EE2A 2Y2XA 3WI4A 4XNLA 4LSFA 3BRZA 5DIPA 3WU2O 4AYMC 4UB8O 4AYDC 2O4VA 3DWOX 3BS0A 4RJXA 3VZTX 2F1CX 4E1SA 2MNHA 1GFOA 4JCHA 5G39A 2KC0A 3AA7B 4FSOA 5PRNA 4FZLA 4AKRB 8PRNA 3A0HO 4UB6O 2Q0TA 3AAAB 1PRNA 2F1VA 5E79O 4G76A 5B66O 3NSGA 3LK41 2ES9A 2QEUA 3GP6A 4KR4A 1QJ8A 2JMMA 3VE1A 1BXWA 4FRTA 2KDYA 3AA1A 4GCPA 5DL5A 2R4PA 4GCSA 2GMYA 3BRYA 5DIKA 1ZHWA 3LK3A 5DL7A 2Y0LA 3POXA 1GFMA 4AYNA 4C00A 1E54A 3A0BO 2Y0KA 3PGUA 2XE2A 1IZNB 3JTYA 3SZDA 3VY9X 2QTKA 4E1TA 2R4LA 3DWNA 4Z3TA 3POUA 3PQSA 3LK42 2WVPA 1T16A 3FYXA 1QJPA 5KAFO 2IWWA 4O49A 3VE2A 4O3XB 2X9KA 3AA1B 4IL6O 2PORA 3SYSA 4N58A 3T0SA 3WI5A 3LK3B 4D64A 3AAAA 1OPFA 3PGRA 2KZ7B 2K4TA 2PRNA 3G7GA 2K0LA 5DL6A 5KAIO 4D5UA 4B61A 3VZUX 3PORA 1HXXA 2X27X 3VZWX 1ZHTA 4K3CA 2KXPA 1QJ9A 1ZHYA 2XG6A 4U9CA 3KVDD 3HW9A 6PRNA 3C5OA 3UAQA 5AFUK 3AAEB 2XE5A 1ME5A 5G3AA 2YNKA 3DA3A 1BT9A 5G38A 1IZNA 3SYBA 3T24A 2M06A 4N59A 4KR8A 3EMNX 2WJQA 4XNKA 2R4NA 1HXUA 2MHLA 2KXPB 2XTQA 4N74A 5GV0A 1MPFA 2AXTO 2OUWA 4KRAA 2WJRA 1PHOA 2IWVA 4PJ0O 2KZ7A 4O3ZA 5IYUA 2M07A 3O0EA 1HXTA 4FMSA 4PUXA 1YS5A 2J4UP 2W81C 3AA6B 4AFKA 2J1NA 3KZIO 4FQEA 3PRNA 4AUIA 4AYID 1KNCA 1BH3A 3HWBA 3TZGA 2YPVA 2FGRA 4F4BA 4G75A 3AAEA 2ERVA 3UU2A 1ZHZA 4GCQA 4FZMA 1T1LA 3C1LA 3K19A 4BUMX 2JQYA 5H2FO 4FUVA 1MM5A 3PQUA 4O3YA 2PFXA 2AF7A 4RLCA 2XMXA 4RJWA 4FRXA 4FSPA 2R8AA 3D7IA 4O4XA 4CTDA 4K3BA 5GTIO 1P8CA 4LSHA 3PF1A 4AYEC 1Q9GA 2ZFGA 3PGSA 2O4DA 4FOZA 3LK2A 1GU9A 3T20A 4AZLA 2CWQA 4LSIA 2IJCA 4O3WA 3HOLA 4JFBA 2LFUA 5D5DA 3AA6A 2LHFA 3POQA 3SY7A 1GFNA 5B5EO 1G90A 1MM4A 2Y0HA 4FESA 2F1TA 3DZMA 1ORMA 3AA0A 1THQA 2R4OA 5ADXL 1H6S1 5GTHO 3HOEA 5G26A 2FGQX 5TISO 3QRAA 4PR7A 4GHBA 1VKEA 3LK2B 5DL8A 4C4VA
chains in the Genus database with same CATH topology
5FVNA 4D5UA 4LSEA 4B61A 3VZUX 3TZGA 2YPVA 2FGRA 3PORA 7PRNA 1HXXA 2X27X 3VZWX 2ZLDA 4F4BA 4G75A 1ZHTA 3A2SX 2Q0TA 3AAEA 3AAAB 2ERVA 2KXPA 1QJ9A 2XE1A 3UU2A 2ODJA 1ZHYA 1ZHZA 4GCQA 1PRNA 2F1VA 4G76A 4FZMA 2XG6A 4AKMA 2N2LA 2XE3A 3NSGA 3C1LA 1LW1A 3KVDD 4FT6A 4U9CA 2OYOA 4G9QA 1GFPA 1OSMA 3LK41 2ES9A 2QEUA 3HW9A 3UPGA 3K19A 4BUMX 3GP6A 4GF4A 4KR4A 1QJ8A 2PRRA 2W80C 2JMMA 4FZNA 6PRNA 3C5OA 3UAQA 3LVYA 5AFUK 3V8UA 3AA0B 3AAEB 2GE4A 2XE5A 1ME5A 4FUVA 3VE1A 2Y7SA 2YNKA 1MM5A 3DA3A 5ADXK 1BXWA 1BT9A 1Q9FA 2KDYA 1IZNA 3AA1A 2N2MA 3PQUA 3QRCA 2PFXA 4FRTA 4GCPA 4O3YA 3SYBA 2AF7A 4RLCA 5DL5A 3T24A 2XMXA 2M06A 4GCSA 4N59A 4QQ1A 2GMYA 4RJWA 5T5FA 4RL9A 5DIKA 3VY8X 4FRXA 2XTRA 4FSPA 4KR8A 4RLBA 3D7IA 1ZHWA 1GFQA 1ZHXA 4O4XA 3LK3A 5DL7A 2Y0LA 3EMNX 3POXA 1GFMA 1P8CA 4D65A 4AYNA 4LSHA 1E54A 3SZVA 4XNKA 2Y0KA 4AYEC 4C69X 1Q9GA 2ZFGA 4O4UA 2XE2A 1IZNB 3AA7A 3JTYA 2O4DA 5AFUL 1HXUA 4FOZA 3RBHA 3LK2A 2MHLA 1GU9A 2JN8A 4AKRA 2KXPB 3BEYA 3SY9A 3SZDA 5JDPA 3T20A 4AZLA 2CWQA 2XTQA 4LSIA 2IJCA 5GV0A 1MPFA 2QTKA 4O3WA 3HOLA 3VY9X 4E1TA 4Z3TA 4JFBA 2OMFA 3DA4A 3POUA 2OUWA 1P4TA 5EE2A 2LFUA 2Y2XA 3WI4A 5D5DA 4XNLA 3PQSA 4LSFA 3LK42 4KRAA 1PHOA 3AA6A 5DIPA 2LHFA 3POQA 3SY7A 3FYXA 1GFNA 1QJPA 4AYMC 4O49A 1G90A 4AYDC 2KZ7A 2O4VA 4O3XB 3VE2A 1MM4A 2Y0HA 4O3ZA 3AA1B 4FESA 5IYUA 2M07A 3O0EA 2F1TA 2PORA 1ORMA 3SYSA 1HXTA 4FMSA 4N58A 3T0SA 3AA0A 4PUXA 1THQA 1YS5A 2J4UP 5ADXL 4RJXA 3VZTX 1H6S1 2W81C 3WI5A 3AA6B 3LK3B 4AFKA 4E1SA 2MNHA 1GFOA 2J1NA 4D64A 4JCHA 3AAAA 1OPFA 2KZ7B 2K4TA 3PRNA 4AUIA 3HOEA 5G26A 2PRNA 2FGQX 2KC0A 3G7GA 3AA7B 3QRAA 8PRNA 2K0LA 4FSOA 4GHBA 1VKEA 3LK2B 4FZLA 5PRNA 4AKRB 4AYID 5DL8A 1KNCA 1BH3A 5DL6A 3HWBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AFU L;  3AAE B;  3LK2 A;  4AKR A;  2KXP B;  5ADX K;  3AA1 A;  1IZN A;  3AA0 A;  5ADX L;  3AAE A;  3AAA B;  2KXP A;  3AA6 B;  3LK3 B;  3LK4 2;  3AAA A;  3LK3 A;  2KZ7 B;  3AA6 A;  3LK4 1;  3AA7 B;  3LK2 B;  2KZ7 A;  4AKR B;  1IZN B;  3AA7 A;  5AFU K;  3AA1 B;  3AA0 B; 
#chains in the Genus database with same CATH topology
 5FVN A;  4LSE A;  7PRN A;  2ZLD A;  3A2S X;  2XE1 A;  2ODJ A;  2N2L A;  2XE3 A;  1LW1 A;  4FT6 A;  4N75 A;  2OYO A;  4G9Q A;  1GFP A;  1OSM A;  3UPG A;  4GF4 A;  2PRR A;  2W80 C;  4FZN A;  3LVY A;  3V8U A;  3AA0 B;  2GE4 A;  2Y7S A;  5ADX K;  3QRC A;  1Q9F A;  4AKM A;  2N2M A;  4QQ1 A;  5T5F A;  4RL9 A;  3VY8 X;  2XTR A;  3JCU O;  4RLB A;  1GFQ A;  1ZHX A;  2R89 A;  4C4V B;  4D65 A;  1S5L O;  3SZV A;  4C69 X;  3NJT A;  4O4U A;  3AA7 A;  5AFU L;  3RBH A;  2JN8 A;  4AKR A;  5JDP A;  3BEY A;  3SY9 A;  2R88 A;  2OMF A;  3DA4 A;  1P4T A;  5EE2 A;  2Y2X A;  3WI4 A;  4XNL A;  4LSF A;  3BRZ A;  5DIP A;  3WU2 O;  4AYM C;  4UB8 O;  4AYD C;  2O4V A;  3DWO X;  3BS0 A;  4RJX A;  3VZT X;  2F1C X;  4E1S A;  2MNH A;  1GFO A;  4JCH A;  5G39 A;  2KC0 A;  3AA7 B;  4FSO A;  5PRN A;  4FZL A;  4AKR B;  8PRN A;  3A0H O;  4UB6 O;  2Q0T A;  3AAA B;  1PRN A;  2F1V A;  5E79 O;  4G76 A;  5B66 O;  3NSG A;  3LK4 1;  2ES9 A;  2QEU A;  3GP6 A;  4KR4 A;  1QJ8 A;  2JMM A;  3VE1 A;  1BXW A;  4FRT A;  2KDY A;  3AA1 A;  4GCP A;  5DL5 A;  2R4P A;  4GCS A;  2GMY A;  3BRY A;  5DIK A;  1ZHW A;  3LK3 A;  5DL7 A;  2Y0L A;  3POX A;  1GFM A;  4AYN A;  4C00 A;  1E54 A;  3A0B O;  2Y0K A;  3PGU A;  2XE2 A;  1IZN B;  3JTY A;  3SZD A;  3VY9 X;  2QTK A;  4E1T A;  2R4L A;  3DWN A;  4Z3T A;  3POU A;  3PQS A;  3LK4 2;  2WVP A;  1T16 A;  3FYX A;  1QJP A;  5KAF O;  2IWW A;  4O49 A;  3VE2 A;  4O3X B;  2X9K A;  3AA1 B;  4IL6 O;  2POR A;  3SYS A;  4N58 A;  3T0S A;  3WI5 A;  3LK3 B;  4D64 A;  3AAA A;  1OPF A;  3PGR A;  2KZ7 B;  2K4T A;  2PRN A;  3G7G A;  2K0L A;  5DL6 A;  5KAI O;  4D5U A;  4B61 A;  3VZU X;  3POR A;  1HXX A;  2X27 X;  3VZW X;  1ZHT A;  4K3C A;  2KXP A;  1QJ9 A;  1ZHY A;  2XG6 A;  4U9C A;  3KVD D;  3HW9 A;  6PRN A;  3C5O A;  3UAQ A;  5AFU K;  3AAE B;  2XE5 A;  1ME5 A;  5G3A A;  2YNK A;  3DA3 A;  1BT9 A;  5G38 A;  1IZN A;  3SYB A;  3T24 A;  2M06 A;  4N59 A;  4KR8 A;  3EMN X;  2WJQ A;  4XNK A;  2R4N A;  1HXU A;  2MHL A;  2KXP B;  2XTQ A;  4N74 A;  5GV0 A;  1MPF A;  2AXT O;  2OUW A;  4KRA A;  2WJR A;  1PHO A;  2IWV A;  4PJ0 O;  2KZ7 A;  4O3Z A;  5IYU A;  2M07 A;  3O0E A;  1HXT A;  4FMS A;  4PUX A;  1YS5 A;  2J4U P;  2W81 C;  3AA6 B;  4AFK A;  2J1N A;  3KZI O;  4FQE A;  3PRN A;  4AUI A;  4AYI D;  1KNC A;  1BH3 A;  3HWB A;  3TZG A;  2YPV A;  2FGR A;  4F4B A;  4G75 A;  3AAE A;  2ERV A;  3UU2 A;  1ZHZ A;  4GCQ A;  4FZM A;  1T1L A;  3C1L A;  3K19 A;  4BUM X;  2JQY A;  5H2F O;  4FUV A;  1MM5 A;  3PQU A;  4O3Y A;  2PFX A;  2AF7 A;  4RLC A;  2XMX A;  4RJW A;  4FRX A;  4FSP A;  2R8A A;  3D7I A;  4O4X A;  4CTD A;  4K3B A;  5GTI O;  1P8C A;  4LSH A;  3PF1 A;  4AYE C;  1Q9G A;  2ZFG A;  3PGS A;  2O4D A;  4FOZ A;  3LK2 A;  1GU9 A;  3T20 A;  4AZL A;  2CWQ A;  4LSI A;  2IJC A;  4O3W A;  3HOL A;  4JFB A;  2LFU A;  5D5D A;  3AA6 A;  2LHF A;  3POQ A;  3SY7 A;  1GFN A;  5B5E O;  1G90 A;  1MM4 A;  2Y0H A;  4FES A;  2F1T A;  3DZM A;  1ORM A;  3AA0 A;  1THQ A;  2R4O A;  5ADX L;  1H6S 1;  5GTH O;  3HOE A;  5G26 A;  2FGQ X;  5TIS O;  3QRA A;  4PR7 A;  4GHB A;  1VKE A;  3LK2 B;  5DL8 A;  4C4V A; 
#chains in the Genus database with same CATH homology
 5FVN A;  4D5U A;  4LSE A;  4B61 A;  3VZU X;  3TZG A;  2YPV A;  2FGR A;  3POR A;  7PRN A;  1HXX A;  2X27 X;  3VZW X;  2ZLD A;  4F4B A;  4G75 A;  1ZHT A;  3A2S X;  2Q0T A;  3AAE A;  3AAA B;  2ERV A;  2KXP A;  1QJ9 A;  2XE1 A;  3UU2 A;  2ODJ A;  1ZHY A;  1ZHZ A;  4GCQ A;  1PRN A;  2F1V A;  4G76 A;  4FZM A;  2XG6 A;  4AKM A;  2N2L A;  2XE3 A;  3NSG A;  3C1L A;  1LW1 A;  3KVD D;  4FT6 A;  4U9C A;  2OYO A;  4G9Q A;  1GFP A;  1OSM A;  3LK4 1;  2ES9 A;  2QEU A;  3HW9 A;  3UPG A;  3K19 A;  4BUM X;  3GP6 A;  4GF4 A;  4KR4 A;  1QJ8 A;  2PRR A;  2W80 C;  2JMM A;  4FZN A;  6PRN A;  3C5O A;  3UAQ A;  3LVY A;  5AFU K;  3V8U A;  3AA0 B;  3AAE B;  2GE4 A;  2XE5 A;  1ME5 A;  4FUV A;  3VE1 A;  2Y7S A;  2YNK A;  1MM5 A;  3DA3 A;  5ADX K;  1BXW A;  1BT9 A;  1Q9F A;  2KDY A;  1IZN A;  3AA1 A;  2N2M A;  3PQU A;  3QRC A;  2PFX A;  4FRT A;  4GCP A;  4O3Y A;  3SYB A;  2AF7 A;  4RLC A;  5DL5 A;  3T24 A;  2XMX A;  2M06 A;  4GCS A;  4N59 A;  4QQ1 A;  2GMY A;  4RJW A;  5T5F A;  4RL9 A;  5DIK A;  3VY8 X;  4FRX A;  2XTR A;  4FSP A;  4KR8 A;  4RLB A;  3D7I A;  1ZHW A;  1GFQ A;  1ZHX A;  4O4X A;  3LK3 A;  5DL7 A;  2Y0L A;  3EMN X;  3POX A;  1GFM A;  1P8C A;  4D65 A;  4AYN A;  4LSH A;  1E54 A;  3SZV A;  4XNK A;  2Y0K A;  4AYE C;  4C69 X;  1Q9G A;  2ZFG A;  4O4U A;  2XE2 A;  1IZN B;  3AA7 A;  3JTY A;  2O4D A;  5AFU L;  1HXU A;  4FOZ A;  3RBH A;  3LK2 A;  2MHL A;  1GU9 A;  2JN8 A;  4AKR A;  2KXP B;  3BEY A;  3SY9 A;  3SZD A;  5JDP A;  3T20 A;  4AZL A;  2CWQ A;  2XTQ A;  4LSI A;  2IJC A;  5GV0 A;  1MPF A;  2QTK A;  4O3W A;  3HOL A;  3VY9 X;  4E1T A;  4Z3T A;  4JFB A;  2OMF A;  3DA4 A;  3POU A;  2OUW A;  1P4T A;  5EE2 A;  2LFU A;  2Y2X A;  3WI4 A;  5D5D A;  4XNL A;  3PQS A;  4LSF A;  3LK4 2;  4KRA A;  1PHO A;  3AA6 A;  5DIP A;  2LHF A;  3POQ A;  3SY7 A;  3FYX A;  1GFN A;  1QJP A;  4AYM C;  4O49 A;  1G90 A;  4AYD C;  2KZ7 A;  2O4V A;  4O3X B;  3VE2 A;  1MM4 A;  2Y0H A;  4O3Z A;  3AA1 B;  4FES A;  5IYU A;  2M07 A;  3O0E A;  2F1T A;  2POR A;  1ORM A;  3SYS A;  1HXT A;  4FMS A;  4N58 A;  3T0S A;  3AA0 A;  4PUX A;  1THQ A;  1YS5 A;  2J4U P;  5ADX L;  4RJX A;  3VZT X;  1H6S 1;  2W81 C;  3WI5 A;  3AA6 B;  3LK3 B;  4AFK A;  4E1S A;  2MNH A;  1GFO A;  2J1N A;  4D64 A;  4JCH A;  3AAA A;  1OPF A;  2KZ7 B;  2K4T A;  3PRN A;  4AUI A;  3HOE A;  5G26 A;  2PRN A;  2FGQ X;  2KC0 A;  3G7G A;  3AA7 B;  3QRA A;  8PRN A;  2K0L A;  4FSO A;  4GHB A;  1VKE A;  3LK2 B;  4FZL A;  5PRN A;  4AKR B;  4AYI D;  5DL8 A;  1KNC A;  1BH3 A;  5DL6 A;  3HWB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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