5ADXK

Cryoem structure of dynactin complex at 4.0 angstrom resolution
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
275
structure length
275
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEVDGSLKSWRESCDSALRAYVKDHYSNGFCTVYAKNIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEAQTAKEFIKIIEHAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the Dynactin Complex and its Interaction with Dynein.
pubmed doi rcsb
molecule tags Structural protein
molecule keywords ACTIN RELATED PROTEIN 1
total genus 65
structure length 275
sequence length 275
ec nomenclature
pdb deposition date 2015-08-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 5adxK01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 5adxK02
2KZ7A 3AAAB 5ADXL 3AA0A 3LK3A 5AFUK 3AA6B 3AAEA 3AAAA 3LK2B 3AA7B 3AA1B 2KXPB 4AKRB 3AA6A 1IZNB 2KZ7B 3LK42 5AFUL 3LK41 3LK2A 3AAEB 3AA7A 5ADXK 3AA1A 2KXPA 3AA0B 3LK3B 4AKRA 1IZNA
chains in the Genus database with same CATH superfamily
2QEUA 1MM4A 3SZVA 5E79O 5AFUK 3SYBA 4K3CA 1T16A 2IWWA 2M07A 4AUIA 4FT6A 4FZLA 2JMMA 3BRZA 4O3YA 5DIKA 2X9KA 3QRCA 1GFMA 3DWNA 2FGRA 3T0SA 3AA1A 4K3BA 4LSIA 3DA4A 3AA0B 2OYOA 1P8CA 3PRNA 4FQEA 3C5OA 1QJ8A 4O3ZA 5ADXL 3AAAA 4FMSA 4C69X 3QRAA 4AYEC 1BT9A 2X27X 2Y0LA 1S5LO 2XMXA 5DL8A 3A0HO 4Z3TA 1IZNA 4O4UA 4D5UA 5EE2A 1GFNA 4AKMA 3V8UA 2R4NA 4LSFA 2R88A 2PRRA 1OSMA 4KR8A 1MPFA 3SY9A 4RJXA 2XE3A 1ZHWA 3AA7A 2Y0HA 4N74A 4UB6O 4AYNA 5FVNA 2YPVA 2OMFA 1OPFA 2LHFA 2N2LA 3AA1B 5DL6A 5TISO 2GE4A 4JFBA 3A2SX 4D64A 1GFQA 2KDYA 3AAAB 4N58A 5D5DA 4E1SA 1GFOA 2ZFGA 3KVDD 4C4VA 4PJ0O 1IZNB 2LFUA 5AFUL 2R4OA 4RLCA 3HWBA 2Y2XA 4AFKA 3PF1A 3LK3A 1HXTA 3SZDA 3GP6A 3AA7B 3POXA 4B61A 4FSPA 2W81C 2KC0A 3TZGA 1GFPA 3JTYA 3WI5A 1ZHZA 3HOEA 3FYXA 1QJ9A 4RL9A 2KZ7A 5KAFO 3SY7A 4E1TA 1THQA 3T24A 3O0EA 2WJQA 3RBHA 3PQUA 3JCUO 2AF7A 1PHOA 5G26A 4GHBA 3POQA 4QQ1A 3AA6A 3KZIO 4XNKA 1ME5A 3VZUX 4O3WA 3G7GA 1ZHTA 1ZHYA 2M06A 5IYUA 4RJWA 3NSGA 4C4VB 2J1NA 4AYID 4N75A 4BUMX 4RLBA 5JDPA 1KNCA 4FESA 3NJTA 4AYDC 2K4TA 1HXUA 2IJCA 3BEYA 3VZWX 3UU2A 2ES9A 4KRAA 7PRNA 2R4PA 8PRNA 3DA3A 3VY8X 3LK3B 5G3AA 4AKRA 2F1CX 4U9CA 1E54A 4PR7A 3POUA 1MM5A 2R8AA 2XE2A 2J4UP 2WJRA 4JCHA 2O4DA 4GCSA 3LVYA 1PRNA 4AZLA 2KZ7B 3D7IA 3LK41 2WVPA 2AXTO 3PORA 2Q0TA 1HXXA 2FGQX 3A0BO 5T5FA 4LSHA 5GTIO 3DZMA 4C00A 4F4BA 3VE1A 3AA6B 1ZHXA 2Y7SA 2ODJA 2XTQA 2JQYA 3LK42 3LK2A 3EMNX 5KAIO 3VZTX 6PRNA 4FZMA 1LW1A 3HW9A 4IL6O 2W80C 2GMYA 5B5EO 3AAEA 4FOZA 4O3XB 3WU2O 4LSEA 5DL7A 3UAQA 4O49A 4AKRB 4G75A 4CTDA 3UPGA 5GV0A 2MHLA 1BH3A 1ORMA 3PQSA 5H2FO 4D65A 2R89A 3DWOX 4UB8O 2PRNA 3PGRA 4GCQA 1G90A 5GTHO 5G39A 1Q9GA 3SYSA 3VY9X 4FUVA 4G76A 5DL5A 5ADXK 1GU9A 4GF4A 3C1LA 2KXPA 1P4TA 2ZLDA 2IWVA 3K19A 2XE5A 4FZNA 4KR4A 3LK2B 2MNHA 4FRXA 1QJPA 2O4VA 2JN8A 3AAEB 5B66O 3BRYA 2XE1A 4O4XA 5G38A 2N2MA 2OUWA 1T1LA 2XG6A 4N59A 3PGUA 3PGSA 4XNLA 2F1VA 2K0LA 1Q9FA 1YS5A 2F1TA 2PFXA 2PORA 3HOLA 2QTKA 5DIPA 2Y0KA 2R4LA 4FSOA 3T20A 4G9QA 3AA0A 1H6S1 5PRNA 2CWQA 2XTRA 4GCPA 1VKEA 2KXPB 3VE2A 4PUXA 3WI4A 2ERVA 3BS0A 1BXWA 2YNKA 4AYMC 4FRTA
chains in the Genus database with same CATH topology
2QEUA 1MM4A 4D65A 2J1NA 5FVNA 3SZVA 4AYID 5AFUK 2YPVA 2OMFA 3SYBA 2PRNA 1OPFA 2LHFA 4RLBA 4BUMX 4GCQA 1KNCA 2N2LA 5JDPA 4FESA 3AA1B 4AYDC 1G90A 2K4TA 5DL6A 1HXUA 2IJCA 3BEYA 3VZWX 1Q9GA 3SYSA 3VY9X 4FUVA 3UU2A 2ES9A 4G76A 5DL5A 5ADXK 1GU9A 4GF4A 4KRAA 3C1LA 7PRNA 2M07A 8PRNA 2KXPA 2GE4A 4JFBA 1P4TA 3A2SX 3DA3A 3VY8X 4AUIA 3LK3B 4AKRA 4D64A 2ZLDA 4U9CA 4FT6A 1GFQA 1E54A 4FZLA 2KDYA 3AAAB 3POUA 2JMMA 4AYNA 4N58A 4O3YA 1MM5A 3K19A 5DIKA 2XE2A 5D5DA 2J4UP 3QRCA 4E1SA 2XE5A 1GFMA 4FZNA 4KR4A 3LK2B 4JCHA 4AYMC 1GFOA 2FGRA 2ZFGA 3KVDD 3T0SA 2O4DA 2MNHA 4FRXA 1QJPA 4GCSA 3LVYA 1PRNA 1IZNB 2O4VA 2JN8A 2LFUA 4AZLA 2KZ7B 5AFUL 3D7IA 3LK41 3AA1A 3PORA 4LSIA 3DA4A 3AA0B 2Q0TA 1HXXA 2FGQX 2OYOA 4RLCA 3HWBA 2Y2XA 3AAEB 1P8CA 3PRNA 5T5FA 4AFKA 3C5OA 4LSHA 1QJ8A 4O3ZA 2XE1A 5ADXL 4O4XA 3LK3A 1HXTA 4F4BA 3SZDA 3AA6B 3VE1A 2N2MA 1ZHXA 3GP6A 3AAAA 4FMSA 3AA7B 3POXA 2OUWA 2ODJA 2Y7SA 2XG6A 4C69X 4B61A 4FSPA 2XTQA 3QRAA 4N59A 2W81C 4XNLA 2F1VA 2KC0A 2K0LA 3TZGA 3LK42 3LK2A 4AYEC 3EMNX 1GFPA 1BT9A 3VZTX 2X27X 6PRNA 1Q9FA 2Y0LA 1YS5A 2F1TA 2PFXA 2XMXA 3JTYA 5DL8A 2PORA 3WI5A 1ZHZA 3HOLA 2QTKA 3HOEA 1IZNA 1LW1A 1QJ9A 5DIPA 2Y0KA 3FYXA 2KZ7A 4FZMA 3HW9A 4O4UA 4FSOA 4RL9A 3SY7A 3T20A 4D5UA 4G9QA 4E1TA 2W80C 5EE2A 3AA0A 1THQA 2GMYA 1GFNA 4AKMA 3T24A 4Z3TA 3V8UA 3O0EA 3AAEA 4LSFA 1H6S1 3RBHA 3PQUA 5PRNA 2CWQA 2XTRA 2PRRA 4FOZA 4O3XB 1OSMA 4GCPA 2AF7A 1VKEA 1PHOA 4KR8A 5G26A 2KXPB 1MPFA 4GHBA 4LSEA 5DL7A 3UAQA 3SY9A 3POQA 4O49A 4QQ1A 4RJXA 3VE2A 4AKRB 3AA6A 4G75A 4PUXA 2XE3A 4XNKA 1ME5A 3VZUX 3WI4A 3UPGA 1ZHWA 3AA7A 2ERVA 4O3WA 2Y0HA 3G7GA 5GV0A 1ZHTA 1ZHYA 2M06A 2MHLA 1BXWA 5IYUA 1BH3A 4RJWA 1ORMA 2YNKA 3NSGA 4FRTA 3PQSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KZ7 A;  3AAA B;  5ADX L;  3AA0 A;  3LK3 A;  5AFU K;  3AA6 B;  3AAE A;  3AAA A;  3LK2 B;  3AA7 B;  3AA1 B;  2KXP B;  4AKR B;  3AA6 A;  1IZN B;  2KZ7 B;  3LK4 2;  5AFU L;  3LK4 1;  3LK2 A;  3AAE B;  3AA7 A;  5ADX K;  3AA1 A;  2KXP A;  3AA0 B;  3LK3 B;  4AKR A;  1IZN A; 
#chains in the Genus database with same CATH topology
 2QEU A;  1MM4 A;  3SZV A;  5E79 O;  5AFU K;  3SYB A;  4K3C A;  1T16 A;  2IWW A;  2M07 A;  4AUI A;  4FT6 A;  4FZL A;  2JMM A;  3BRZ A;  4O3Y A;  5DIK A;  2X9K A;  3QRC A;  1GFM A;  3DWN A;  2FGR A;  3T0S A;  3AA1 A;  4K3B A;  4LSI A;  3DA4 A;  3AA0 B;  2OYO A;  1P8C A;  3PRN A;  4FQE A;  3C5O A;  1QJ8 A;  4O3Z A;  5ADX L;  3AAA A;  4FMS A;  4C69 X;  3QRA A;  4AYE C;  1BT9 A;  2X27 X;  2Y0L A;  1S5L O;  2XMX A;  5DL8 A;  3A0H O;  4Z3T A;  1IZN A;  4O4U A;  4D5U A;  5EE2 A;  1GFN A;  4AKM A;  3V8U A;  2R4N A;  4LSF A;  2R88 A;  2PRR A;  1OSM A;  4KR8 A;  1MPF A;  3SY9 A;  4RJX A;  2XE3 A;  1ZHW A;  3AA7 A;  2Y0H A;  4N74 A;  4UB6 O;  4AYN A;  5FVN A;  2YPV A;  2OMF A;  1OPF A;  2LHF A;  2N2L A;  3AA1 B;  5DL6 A;  5TIS O;  2GE4 A;  4JFB A;  3A2S X;  4D64 A;  1GFQ A;  2KDY A;  3AAA B;  4N58 A;  5D5D A;  4E1S A;  1GFO A;  2ZFG A;  3KVD D;  4C4V A;  4PJ0 O;  1IZN B;  2LFU A;  5AFU L;  2R4O A;  4RLC A;  3HWB A;  2Y2X A;  4AFK A;  3PF1 A;  3LK3 A;  1HXT A;  3SZD A;  3GP6 A;  3AA7 B;  3POX A;  4B61 A;  4FSP A;  2W81 C;  2KC0 A;  3TZG A;  1GFP A;  3JTY A;  3WI5 A;  1ZHZ A;  3HOE A;  3FYX A;  1QJ9 A;  4RL9 A;  2KZ7 A;  5KAF O;  3SY7 A;  4E1T A;  1THQ A;  3T24 A;  3O0E A;  2WJQ A;  3RBH A;  3PQU A;  3JCU O;  2AF7 A;  1PHO A;  5G26 A;  4GHB A;  3POQ A;  4QQ1 A;  3AA6 A;  3KZI O;  4XNK A;  1ME5 A;  3VZU X;  4O3W A;  3G7G A;  1ZHT A;  1ZHY A;  2M06 A;  5IYU A;  4RJW A;  3NSG A;  4C4V B;  2J1N A;  4AYI D;  4N75 A;  4BUM X;  4RLB A;  5JDP A;  1KNC A;  4FES A;  3NJT A;  4AYD C;  2K4T A;  1HXU A;  2IJC A;  3BEY A;  3VZW X;  3UU2 A;  2ES9 A;  4KRA A;  7PRN A;  2R4P A;  8PRN A;  3DA3 A;  3VY8 X;  3LK3 B;  5G3A A;  4AKR A;  2F1C X;  4U9C A;  1E54 A;  4PR7 A;  3POU A;  1MM5 A;  2R8A A;  2XE2 A;  2J4U P;  2WJR A;  4JCH A;  2O4D A;  4GCS A;  3LVY A;  1PRN A;  4AZL A;  2KZ7 B;  3D7I A;  3LK4 1;  2WVP A;  2AXT O;  3POR A;  2Q0T A;  1HXX A;  2FGQ X;  3A0B O;  5T5F A;  4LSH A;  5GTI O;  3DZM A;  4C00 A;  4F4B A;  3VE1 A;  3AA6 B;  1ZHX A;  2Y7S A;  2ODJ A;  2XTQ A;  2JQY A;  3LK4 2;  3LK2 A;  3EMN X;  5KAI O;  3VZT X;  6PRN A;  4FZM A;  1LW1 A;  3HW9 A;  4IL6 O;  2W80 C;  2GMY A;  5B5E O;  3AAE A;  4FOZ A;  4O3X B;  3WU2 O;  4LSE A;  5DL7 A;  3UAQ A;  4O49 A;  4AKR B;  4G75 A;  4CTD A;  3UPG A;  5GV0 A;  2MHL A;  1BH3 A;  1ORM A;  3PQS A;  5H2F O;  4D65 A;  2R89 A;  3DWO X;  4UB8 O;  2PRN A;  3PGR A;  4GCQ A;  1G90 A;  5GTH O;  5G39 A;  1Q9G A;  3SYS A;  3VY9 X;  4FUV A;  4G76 A;  5DL5 A;  5ADX K;  1GU9 A;  4GF4 A;  3C1L A;  2KXP A;  1P4T A;  2ZLD A;  2IWV A;  3K19 A;  2XE5 A;  4FZN A;  4KR4 A;  3LK2 B;  2MNH A;  4FRX A;  1QJP A;  2O4V A;  2JN8 A;  3AAE B;  5B66 O;  3BRY A;  2XE1 A;  4O4X A;  5G38 A;  2N2M A;  2OUW A;  1T1L A;  2XG6 A;  4N59 A;  3PGU A;  3PGS A;  4XNL A;  2F1V A;  2K0L A;  1Q9F A;  1YS5 A;  2F1T A;  2PFX A;  2POR A;  3HOL A;  2QTK A;  5DIP A;  2Y0K A;  2R4L A;  4FSO A;  3T20 A;  4G9Q A;  3AA0 A;  1H6S 1;  5PRN A;  2CWQ A;  2XTR A;  4GCP A;  1VKE A;  2KXP B;  3VE2 A;  4PUX A;  3WI4 A;  2ERV A;  3BS0 A;  1BXW A;  2YNK A;  4AYM C;  4FRT A; 
#chains in the Genus database with same CATH homology
 2QEU A;  1MM4 A;  4D65 A;  2J1N A;  5FVN A;  3SZV A;  4AYI D;  5AFU K;  2YPV A;  2OMF A;  3SYB A;  2PRN A;  1OPF A;  2LHF A;  4RLB A;  4BUM X;  4GCQ A;  1KNC A;  2N2L A;  5JDP A;  4FES A;  3AA1 B;  4AYD C;  1G90 A;  2K4T A;  5DL6 A;  1HXU A;  2IJC A;  3BEY A;  3VZW X;  1Q9G A;  3SYS A;  3VY9 X;  4FUV A;  3UU2 A;  2ES9 A;  4G76 A;  5DL5 A;  5ADX K;  1GU9 A;  4GF4 A;  4KRA A;  3C1L A;  7PRN A;  2M07 A;  8PRN A;  2KXP A;  2GE4 A;  4JFB A;  1P4T A;  3A2S X;  3DA3 A;  3VY8 X;  4AUI A;  3LK3 B;  4AKR A;  4D64 A;  2ZLD A;  4U9C A;  4FT6 A;  1GFQ A;  1E54 A;  4FZL A;  2KDY A;  3AAA B;  3POU A;  2JMM A;  4AYN A;  4N58 A;  4O3Y A;  1MM5 A;  3K19 A;  5DIK A;  2XE2 A;  5D5D A;  2J4U P;  3QRC A;  4E1S A;  2XE5 A;  1GFM A;  4FZN A;  4KR4 A;  3LK2 B;  4JCH A;  4AYM C;  1GFO A;  2FGR A;  2ZFG A;  3KVD D;  3T0S A;  2O4D A;  2MNH A;  4FRX A;  1QJP A;  4GCS A;  3LVY A;  1PRN A;  1IZN B;  2O4V A;  2JN8 A;  2LFU A;  4AZL A;  2KZ7 B;  5AFU L;  3D7I A;  3LK4 1;  3AA1 A;  3POR A;  4LSI A;  3DA4 A;  3AA0 B;  2Q0T A;  1HXX A;  2FGQ X;  2OYO A;  4RLC A;  3HWB A;  2Y2X A;  3AAE B;  1P8C A;  3PRN A;  5T5F A;  4AFK A;  3C5O A;  4LSH A;  1QJ8 A;  4O3Z A;  2XE1 A;  5ADX L;  4O4X A;  3LK3 A;  1HXT A;  4F4B A;  3SZD A;  3AA6 B;  3VE1 A;  2N2M A;  1ZHX A;  3GP6 A;  3AAA A;  4FMS A;  3AA7 B;  3POX A;  2OUW A;  2ODJ A;  2Y7S A;  2XG6 A;  4C69 X;  4B61 A;  4FSP A;  2XTQ A;  3QRA A;  4N59 A;  2W81 C;  4XNL A;  2F1V A;  2KC0 A;  2K0L A;  3TZG A;  3LK4 2;  3LK2 A;  4AYE C;  3EMN X;  1GFP A;  1BT9 A;  3VZT X;  2X27 X;  6PRN A;  1Q9F A;  2Y0L A;  1YS5 A;  2F1T A;  2PFX A;  2XMX A;  3JTY A;  5DL8 A;  2POR A;  3WI5 A;  1ZHZ A;  3HOL A;  2QTK A;  3HOE A;  1IZN A;  1LW1 A;  1QJ9 A;  5DIP A;  2Y0K A;  3FYX A;  2KZ7 A;  4FZM A;  3HW9 A;  4O4U A;  4FSO A;  4RL9 A;  3SY7 A;  3T20 A;  4D5U A;  4G9Q A;  4E1T A;  2W80 C;  5EE2 A;  3AA0 A;  1THQ A;  2GMY A;  1GFN A;  4AKM A;  3T24 A;  4Z3T A;  3V8U A;  3O0E A;  3AAE A;  4LSF A;  1H6S 1;  3RBH A;  3PQU A;  5PRN A;  2CWQ A;  2XTR A;  2PRR A;  4FOZ A;  4O3X B;  1OSM A;  4GCP A;  2AF7 A;  1VKE A;  1PHO A;  4KR8 A;  5G26 A;  2KXP B;  1MPF A;  4GHB A;  4LSE A;  5DL7 A;  3UAQ A;  3SY9 A;  3POQ A;  4O49 A;  4QQ1 A;  4RJX A;  3VE2 A;  4AKR B;  3AA6 A;  4G75 A;  4PUX A;  2XE3 A;  4XNK A;  1ME5 A;  3VZU X;  3WI4 A;  3UPG A;  1ZHW A;  3AA7 A;  2ERV A;  4O3W A;  2Y0H A;  3G7G A;  5GV0 A;  1ZHT A;  1ZHY A;  2M06 A;  2MHL A;  1BXW A;  5IYU A;  1BH3 A;  4RJW A;  1ORM A;  2YNK A;  3NSG A;  4FRT A;  3PQS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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