5AFUK

Cryo-em structure of dynein tail-dynactin-bicd2n complex
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
275
structure length
275
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEVDGSLKSWRESCDSALRAYVKDHYSNGFCTVYAKNIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEAQTAKEFIKIIEHAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the Dynactin Complex and its Interaction with Dynein.
pubmed doi rcsb
molecule tags Motor protein
molecule keywords DYNEIN TAIL
total genus 65
structure length 275
sequence length 275
ec nomenclature
pdb deposition date 2015-01-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 5afuK01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 5afuK02
3AAEA 3LK3A 3AA1A 5AFUK 2KZ7B 4AKRA 3AAAA 3LK2A 5AFUL 2KXPA 3AA6B 3AA0B 1IZNB 3AA7A 3AAEB 2KZ7A 3LK3B 3LK41 5ADXK 3AA1B 3LK42 4AKRB 3AAAB 3LK2B 5ADXL 2KXPB 3AA0A 3AA6A 1IZNA 3AA7B
chains in the Genus database with same CATH superfamily
2XE1A 2J4UP 2X27X 2WVPA 3UAQA 5H2FO 4CTDA 3NJTA 3VE2A 1BXWA 4FRTA 4RJXA 4E1TA 4FSPA 1H6S1 3SZVA 4FT6A 3VY9X 2QTKA 3QRCA 1OSMA 5KAFO 1HXXA 4GCSA 3VZTX 3LVYA 2K4TA 5B66O 3PRNA 4O4UA 4FZMA 4XNLA 3EMNX 1GFQA 2F1TA 2OUWA 5GTIO 2KXPB 1ZHTA 3C1LA 3T20A 2R4LA 2R89A 3AAAA 1Q9GA 2ODJA 4RL9A 3QRAA 4N75A 4PUXA 2MNHA 5ADXK 2YPVA 4AYID 3PGSA 2R4NA 4GCPA 3SYSA 2AF7A 1P8CA 3FYXA 2O4DA 4FSOA 4AYMC 5G39A 3T24A 3D7IA 3BS0A 4RJWA 4UB8O 3BRYA 3PF1A 5DIKA 1QJPA 3UPGA 4O49A 4FZLA 1KNCA 2PORA 1BH3A 1BT9A 3VE1A 4K3BA 4IL6O 3TZGA 3PQUA 2XMXA 4UB6O 3WI4A 4O3WA 5JDPA 3VZWX 4PJ0O 3DA3A 4FUVA 1PRNA 2XTRA 5B5EO 4D65A 1QJ9A 2ZFGA 2F1VA 5TISO 2JN8A 4JFBA 2KZ7A 2LFUA 3AAAB 4AZLA 5ADXL 3SZDA 1GFMA 2WJQA 4AYDC 1Q9FA 2M06A 5GV0A 4RLCA 5DL7A 2FGRA 3HOLA 4G76A 3HOEA 3PGRA 2AXTO 2F1CX 2OMFA 4LSHA 4BUMX 2R8AA 2R88A 3SY9A 2KC0A 3WU2O 1IZNA 5G26A 2J1NA 4E1SA 2M07A 3AA1A 4C4VA 3SY7A 3LK2A 2PFXA 2XE2A 4N59A 2GE4A 3A0HO 3POUA 3VY8X 3SYBA 2ES9A 3LK42 4AYEC 1HXUA 2JMMA 4AUIA 4O3ZA 3DWOX 2Q0TA 5E79O 2PRRA 4Z3TA 2ERVA 4RLBA 4FESA 4LSIA 4O3XB 4B61A 2O4VA 3JCUO 1ZHZA 1HXTA 3VZUX 1T16A 2W80C 8PRNA 3HW9A 1LW1A 4K3CA 1ZHWA 3KVDD 2KZ7B 2XE5A 5AFUL 2JQYA 1S5LO 1ME5A 1ZHXA 3PQSA 1GFNA 5DL6A 2ZLDA 2X9KA 2N2MA 3A0BO 3AA0A 1G90A 4O3YA 4FOZA 4LSEA 2CWQA 1E54A 4C00A 1PHOA 1GFPA 3PORA 3GP6A 4AKMA 4XNKA 3POXA 3AA7A 1IZNB 5DIPA 3AA1B 4O4XA 4C4VB 1MM4A 3G7GA 3LK2B 4FRXA 3AA6A 4LSFA 3DWNA 3V8UA 2YNKA 6PRNA 5AFUK 4AKRA 1MM5A 5KAIO 3POQA 4QQ1A 1GU9A 2LHFA 4F4BA 2Y0KA 3RBHA 1ZHYA 1THQA 2K0LA 4G75A 4FZNA 4AFKA 1OPFA 4D64A 3O0EA 3PGUA 5IYUA 2KDYA 3AAEA 3LK3A 5EE2A 4GCQA 4GHBA 2IWWA 2Y2XA 3JTYA 3K19A 3LK41 4G9QA 5G38A 3NSGA 2W81C 4D5UA 2XTQA 2QEUA 4GF4A 2R4OA 4N74A 3AA0B 2Y7SA 4U9CA 2IJCA 3WI5A 2Y0LA 2XE3A 3C5OA 2GMYA 1T1LA 4N58A 3KZIO 4AYNA 5G3AA 3AA7B 2IWVA 5D5DA 2R4PA 5DL5A 2XG6A 2KXPA 4C69X 3AA6B 1VKEA 5DL8A 5GTHO 3DA4A 3UU2A 4AKRB 3HWBA 2WJRA 4FQEA 5FVNA 2PRNA 2Y0HA 4KR8A 3BEYA 3T0SA 4PR7A 1QJ8A 3DZMA 2OYOA 5T5FA 3A2SX 2N2LA 7PRNA 2MHLA 3AAEB 3LK3B 1YS5A 5PRNA 4FMSA 4KRAA 1GFOA 3BRZA 1ORMA 4JCHA 1P4TA 2FGQX 1MPFA 4KR4A
chains in the Genus database with same CATH topology
2KDYA 3AAEA 4LSIA 2XE1A 4O3XB 3LK3A 4O49A 4GCQA 5EE2A 3UPGA 4FZLA 4B61A 2X27X 2J4UP 1KNCA 3UAQA 2PORA 1BH3A 2O4VA 1BT9A 4GHBA 2Y2XA 1ZHZA 3VE1A 3JTYA 3K19A 3VE2A 1HXTA 3TZGA 3LK41 1BXWA 3PQUA 4FRTA 4RJXA 3VZUX 4E1TA 2XMXA 3WI4A 4G9QA 4FSPA 1H6S1 4O3WA 3VZWX 5JDPA 3SZVA 3DA3A 4FUVA 2W80C 1PRNA 3NSGA 2W81C 2XTRA 3HW9A 4FT6A 1LW1A 4D5UA 1ZHWA 8PRNA 3VY9X 2QTKA 3KVDD 2KZ7B 2XTQA 3QRCA 2QEUA 2XE5A 4D65A 5AFUL 1QJ9A 1OSMA 2ZFGA 4GF4A 1HXXA 4GCSA 2F1VA 3VZTX 2JN8A 3LVYA 3AA0B 2Y7SA 4JFBA 1ME5A 4U9CA 1ZHXA 2IJCA 2K4TA 3WI5A 3PQSA 3PRNA 2KZ7A 2Y0LA 4FZMA 4O4UA 2XE3A 3EMNX 1GFNA 4XNLA 5DL6A 2ZLDA 3C5OA 2LFUA 3AAAB 2GMYA 1GFQA 4AZLA 5ADXL 2F1TA 2OUWA 2N2MA 3SZDA 1GFMA 4N58A 2KXPB 3AA0A 1ZHTA 4AYNA 1G90A 3AA7B 4O3YA 3C1LA 3T20A 4FOZA 4LSEA 2CWQA 5D5DA 1E54A 1PHOA 1GFPA 5DL5A 3AAAA 1Q9FA 1Q9GA 2M06A 4AYDC 4RLCA 5DL7A 5GV0A 2XG6A 2ODJA 3PORA 2FGRA 3GP6A 2KXPA 4AKMA 4C69X 3HOLA 4G76A 3HOEA 3AA6B 4RL9A 4XNKA 3POXA 3AA7A 1IZNB 2OMFA 3QRAA 1VKEA 4LSHA 5DL8A 4PUXA 5DIPA 2MNHA 5ADXK 3AA1B 4BUMX 3DA4A 4O4XA 3UU2A 1MM4A 3HWBA 4AKRB 3G7GA 2YPVA 3LK2B 3SY9A 4AYID 4FRXA 2KC0A 3AA6A 4LSFA 1IZNA 5G26A 4GCPA 2J1NA 3V8UA 2YNKA 4E1SA 3SYSA 6PRNA 2AF7A 2M07A 5FVNA 3AA1A 2PRNA 5AFUK 4AKRA 1P8CA 3SY7A 2Y0HA 3FYXA 3LK2A 4KR8A 3BEYA 3T0SA 1QJ8A 2O4DA 1MM5A 2OYOA 2PFXA 3POQA 4FSOA 3A2SX 4QQ1A 2N2LA 2XE2A 5T5FA 1GU9A 2LHFA 4AYMC 4F4BA 7PRNA 2MHLA 4N59A 2GE4A 3POUA 2Y0KA 3T24A 3RBHA 3VY8X 3AAEB 3D7IA 3LK3B 1ZHYA 3SYBA 2ES9A 1YS5A 3LK42 1THQA 2K0LA 5PRNA 4FMSA 4AYEC 4KRAA 1HXUA 1GFOA 4G75A 4FZNA 4RJWA 1ORMA 2JMMA 4JCHA 4AFKA 4O3ZA 4AUIA 2Q0TA 1OPFA 4Z3TA 2PRRA 1P4TA 5DIKA 1QJPA 2ERVA 4RLBA 4D64A 3O0EA 2FGQX 1MPFA 4FESA 5IYUA 4KR4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AAE A;  3LK3 A;  3AA1 A;  5AFU K;  2KZ7 B;  4AKR A;  3AAA A;  3LK2 A;  5AFU L;  2KXP A;  3AA6 B;  3AA0 B;  1IZN B;  3AA7 A;  3AAE B;  2KZ7 A;  3LK3 B;  3LK4 1;  5ADX K;  3AA1 B;  3LK4 2;  4AKR B;  3AAA B;  3LK2 B;  5ADX L;  2KXP B;  3AA0 A;  3AA6 A;  1IZN A;  3AA7 B; 
#chains in the Genus database with same CATH topology
 2XE1 A;  2J4U P;  2X27 X;  2WVP A;  3UAQ A;  5H2F O;  4CTD A;  3NJT A;  3VE2 A;  1BXW A;  4FRT A;  4RJX A;  4E1T A;  4FSP A;  1H6S 1;  3SZV A;  4FT6 A;  3VY9 X;  2QTK A;  3QRC A;  1OSM A;  5KAF O;  1HXX A;  4GCS A;  3VZT X;  3LVY A;  2K4T A;  5B66 O;  3PRN A;  4O4U A;  4FZM A;  4XNL A;  3EMN X;  1GFQ A;  2F1T A;  2OUW A;  5GTI O;  2KXP B;  1ZHT A;  3C1L A;  3T20 A;  2R4L A;  2R89 A;  3AAA A;  1Q9G A;  2ODJ A;  4RL9 A;  3QRA A;  4N75 A;  4PUX A;  2MNH A;  5ADX K;  2YPV A;  4AYI D;  3PGS A;  2R4N A;  4GCP A;  3SYS A;  2AF7 A;  1P8C A;  3FYX A;  2O4D A;  4FSO A;  4AYM C;  5G39 A;  3T24 A;  3D7I A;  3BS0 A;  4RJW A;  4UB8 O;  3BRY A;  3PF1 A;  5DIK A;  1QJP A;  3UPG A;  4O49 A;  4FZL A;  1KNC A;  2POR A;  1BH3 A;  1BT9 A;  3VE1 A;  4K3B A;  4IL6 O;  3TZG A;  3PQU A;  2XMX A;  4UB6 O;  3WI4 A;  4O3W A;  5JDP A;  3VZW X;  4PJ0 O;  3DA3 A;  4FUV A;  1PRN A;  2XTR A;  5B5E O;  4D65 A;  1QJ9 A;  2ZFG A;  2F1V A;  5TIS O;  2JN8 A;  4JFB A;  2KZ7 A;  2LFU A;  3AAA B;  4AZL A;  5ADX L;  3SZD A;  1GFM A;  2WJQ A;  4AYD C;  1Q9F A;  2M06 A;  5GV0 A;  4RLC A;  5DL7 A;  2FGR A;  3HOL A;  4G76 A;  3HOE A;  3PGR A;  2AXT O;  2F1C X;  2OMF A;  4LSH A;  4BUM X;  2R8A A;  2R88 A;  3SY9 A;  2KC0 A;  3WU2 O;  1IZN A;  5G26 A;  2J1N A;  4E1S A;  2M07 A;  3AA1 A;  4C4V A;  3SY7 A;  3LK2 A;  2PFX A;  2XE2 A;  4N59 A;  2GE4 A;  3A0H O;  3POU A;  3VY8 X;  3SYB A;  2ES9 A;  3LK4 2;  4AYE C;  1HXU A;  2JMM A;  4AUI A;  4O3Z A;  3DWO X;  2Q0T A;  5E79 O;  2PRR A;  4Z3T A;  2ERV A;  4RLB A;  4FES A;  4LSI A;  4O3X B;  4B61 A;  2O4V A;  3JCU O;  1ZHZ A;  1HXT A;  3VZU X;  1T16 A;  2W80 C;  8PRN A;  3HW9 A;  1LW1 A;  4K3C A;  1ZHW A;  3KVD D;  2KZ7 B;  2XE5 A;  5AFU L;  2JQY A;  1S5L O;  1ME5 A;  1ZHX A;  3PQS A;  1GFN A;  5DL6 A;  2ZLD A;  2X9K A;  2N2M A;  3A0B O;  3AA0 A;  1G90 A;  4O3Y A;  4FOZ A;  4LSE A;  2CWQ A;  1E54 A;  4C00 A;  1PHO A;  1GFP A;  3POR A;  3GP6 A;  4AKM A;  4XNK A;  3POX A;  3AA7 A;  1IZN B;  5DIP A;  3AA1 B;  4O4X A;  4C4V B;  1MM4 A;  3G7G A;  3LK2 B;  4FRX A;  3AA6 A;  4LSF A;  3DWN A;  3V8U A;  2YNK A;  6PRN A;  5AFU K;  4AKR A;  1MM5 A;  5KAI O;  3POQ A;  4QQ1 A;  1GU9 A;  2LHF A;  4F4B A;  2Y0K A;  3RBH A;  1ZHY A;  1THQ A;  2K0L A;  4G75 A;  4FZN A;  4AFK A;  1OPF A;  4D64 A;  3O0E A;  3PGU A;  5IYU A;  2KDY A;  3AAE A;  3LK3 A;  5EE2 A;  4GCQ A;  4GHB A;  2IWW A;  2Y2X A;  3JTY A;  3K19 A;  3LK4 1;  4G9Q A;  5G38 A;  3NSG A;  2W81 C;  4D5U A;  2XTQ A;  2QEU A;  4GF4 A;  2R4O A;  4N74 A;  3AA0 B;  2Y7S A;  4U9C A;  2IJC A;  3WI5 A;  2Y0L A;  2XE3 A;  3C5O A;  2GMY A;  1T1L A;  4N58 A;  3KZI O;  4AYN A;  5G3A A;  3AA7 B;  2IWV A;  5D5D A;  2R4P A;  5DL5 A;  2XG6 A;  2KXP A;  4C69 X;  3AA6 B;  1VKE A;  5DL8 A;  5GTH O;  3DA4 A;  3UU2 A;  4AKR B;  3HWB A;  2WJR A;  4FQE A;  5FVN A;  2PRN A;  2Y0H A;  4KR8 A;  3BEY A;  3T0S A;  4PR7 A;  1QJ8 A;  3DZM A;  2OYO A;  5T5F A;  3A2S X;  2N2L A;  7PRN A;  2MHL A;  3AAE B;  3LK3 B;  1YS5 A;  5PRN A;  4FMS A;  4KRA A;  1GFO A;  3BRZ A;  1ORM A;  4JCH A;  1P4T A;  2FGQ X;  1MPF A;  4KR4 A; 
#chains in the Genus database with same CATH homology
 2KDY A;  3AAE A;  4LSI A;  2XE1 A;  4O3X B;  3LK3 A;  4O49 A;  4GCQ A;  5EE2 A;  3UPG A;  4FZL A;  4B61 A;  2X27 X;  2J4U P;  1KNC A;  3UAQ A;  2POR A;  1BH3 A;  2O4V A;  1BT9 A;  4GHB A;  2Y2X A;  1ZHZ A;  3VE1 A;  3JTY A;  3K19 A;  3VE2 A;  1HXT A;  3TZG A;  3LK4 1;  1BXW A;  3PQU A;  4FRT A;  4RJX A;  3VZU X;  4E1T A;  2XMX A;  3WI4 A;  4G9Q A;  4FSP A;  1H6S 1;  4O3W A;  3VZW X;  5JDP A;  3SZV A;  3DA3 A;  4FUV A;  2W80 C;  1PRN A;  3NSG A;  2W81 C;  2XTR A;  3HW9 A;  4FT6 A;  1LW1 A;  4D5U A;  1ZHW A;  8PRN A;  3VY9 X;  2QTK A;  3KVD D;  2KZ7 B;  2XTQ A;  3QRC A;  2QEU A;  2XE5 A;  4D65 A;  5AFU L;  1QJ9 A;  1OSM A;  2ZFG A;  4GF4 A;  1HXX A;  4GCS A;  2F1V A;  3VZT X;  2JN8 A;  3LVY A;  3AA0 B;  2Y7S A;  4JFB A;  1ME5 A;  4U9C A;  1ZHX A;  2IJC A;  2K4T A;  3WI5 A;  3PQS A;  3PRN A;  2KZ7 A;  2Y0L A;  4FZM A;  4O4U A;  2XE3 A;  3EMN X;  1GFN A;  4XNL A;  5DL6 A;  2ZLD A;  3C5O A;  2LFU A;  3AAA B;  2GMY A;  1GFQ A;  4AZL A;  5ADX L;  2F1T A;  2OUW A;  2N2M A;  3SZD A;  1GFM A;  4N58 A;  2KXP B;  3AA0 A;  1ZHT A;  4AYN A;  1G90 A;  3AA7 B;  4O3Y A;  3C1L A;  3T20 A;  4FOZ A;  4LSE A;  2CWQ A;  5D5D A;  1E54 A;  1PHO A;  1GFP A;  5DL5 A;  3AAA A;  1Q9F A;  1Q9G A;  2M06 A;  4AYD C;  4RLC A;  5DL7 A;  5GV0 A;  2XG6 A;  2ODJ A;  3POR A;  2FGR A;  3GP6 A;  2KXP A;  4AKM A;  4C69 X;  3HOL A;  4G76 A;  3HOE A;  3AA6 B;  4RL9 A;  4XNK A;  3POX A;  3AA7 A;  1IZN B;  2OMF A;  3QRA A;  1VKE A;  4LSH A;  5DL8 A;  4PUX A;  5DIP A;  2MNH A;  5ADX K;  3AA1 B;  4BUM X;  3DA4 A;  4O4X A;  3UU2 A;  1MM4 A;  3HWB A;  4AKR B;  3G7G A;  2YPV A;  3LK2 B;  3SY9 A;  4AYI D;  4FRX A;  2KC0 A;  3AA6 A;  4LSF A;  1IZN A;  5G26 A;  4GCP A;  2J1N A;  3V8U A;  2YNK A;  4E1S A;  3SYS A;  6PRN A;  2AF7 A;  2M07 A;  5FVN A;  3AA1 A;  2PRN A;  5AFU K;  4AKR A;  1P8C A;  3SY7 A;  2Y0H A;  3FYX A;  3LK2 A;  4KR8 A;  3BEY A;  3T0S A;  1QJ8 A;  2O4D A;  1MM5 A;  2OYO A;  2PFX A;  3POQ A;  4FSO A;  3A2S X;  4QQ1 A;  2N2L A;  2XE2 A;  5T5F A;  1GU9 A;  2LHF A;  4AYM C;  4F4B A;  7PRN A;  2MHL A;  4N59 A;  2GE4 A;  3POU A;  2Y0K A;  3T24 A;  3RBH A;  3VY8 X;  3AAE B;  3D7I A;  3LK3 B;  1ZHY A;  3SYB A;  2ES9 A;  1YS5 A;  3LK4 2;  1THQ A;  2K0L A;  5PRN A;  4FMS A;  4AYE C;  4KRA A;  1HXU A;  1GFO A;  4G75 A;  4FZN A;  4RJW A;  1ORM A;  2JMM A;  4JCH A;  4AFK A;  4O3Z A;  4AUI A;  2Q0T A;  1OPF A;  4Z3T A;  2PRR A;  1P4T A;  5DIK A;  1QJP A;  2ERV A;  4RLB A;  4D64 A;  3O0E A;  2FGQ X;  1MPF A;  4FES A;  5IYU A;  4KR4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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