5ADXK

Cryoem structure of dynactin complex at 4.0 angstrom resolution
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
275
structure length
275
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEVDGSLKSWRESCDSALRAYVKDHYSNGFCTVYAKNIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEAQTAKEFIKIIEHAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the Dynactin Complex and its Interaction with Dynein.
pubmed doi rcsb
molecule tags Structural protein
molecule keywords ACTIN RELATED PROTEIN 1
total genus 65
structure length 275
sequence length 275
ec nomenclature
pdb deposition date 2015-08-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 5adxK01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 5adxK02
4AKRA 4AKRB 1IZNA 1IZNB 3LK2A 3LK2B 5ADXK 3LK3A 3LK3B 3AA7A 3LK41 3AA7B 3AA0A 2KZ7A 2KZ7B 3AA0B 3AAAA 3AAAB 5ADXL 5AFUK 3LK42 5AFUL 3AA1A 3AA1B 3AA6B 2KXPA 2KXPB 3AA6A 3AAEA 3AAEB
chains in the Genus database with same CATH superfamily
2W81C 5G39A 5GTIO 3V8UA 5H2FO 5DL6A 3A0HO 3LK2A 2XTQA 2Y0KA 3LK3A 3VE1A 1GFMA 5KAFO 3AAAB 5T5FA 5DL5A 4FZNA 4LSIA 4FRXA 2IWWA 1MM5A 1GFPA 1ORMA 3KZIO 2R8AA 3AA1A 3O0EA 1E54A 4AYEC 3HW9A 3PGSA 2QEUA 2AF7A 3DA3A 2IJCA 5TISO 1HXTA 4GCQA 2PORA 4GF4A 4G76A 1QJ8A 5G26A 3C5OA 5GV0A 2OMFA 3NSGA 5EE2A 4GCSA 3BRYA 3UPGA 1P4TA 2KDYA 2XTRA 3VY9X 4O4UA 2KZ7B 3PORA 3DWNA 4G9QA 3K19A 5GTHO 4XNLA 4XNKA 5PRNA 3AA6A 4D64A 3VE2A 2ZLDA 4CTDA 4AKMA 4C69X 3SY9A 4FRTA 2PFXA 6PRNA 1IZNB 2XE3A 3POUA 1PHOA 3UU2A 3AAAA 4O3YA 2X9KA 4RJXA 4AYMC 3POXA 2QTKA 1Q9FA 1VKEA 3DWOX 3PGRA 4BUMX 3VY8X 1BH3A 4C4VB 2LHFA 3PQSA 1ZHXA 3VZTX 2XMXA 1ZHTA 3QRCA 5IYUA 5DL8A 3RBHA 3DZMA 2YPVA 2GMYA 1ZHZA 4AYDC 4O3XB 4UB8O 4G75A 2CWQA 5D5DA 2KZ7A 4O4XA 2MNHA 4PR7A 8PRNA 2ERVA 2Y2XA 2MHLA 3SY7A 4LSHA 3KVDD 1H6S1 1IZNA 2FGRA 2Y0HA 4N75A 5DIKA 3BRZA 3A2SX 3JTYA 1G90A 4PJ0O 4FOZA 2K4TA 2F1VA 3SYSA 1OPFA 2KXPB 3UAQA 3HOEA 1HXUA 2JQYA 4AKRB 3WI4A 2R4NA 4KR4A 4LSFA 3SYBA 4RLCA 4N59A 2R89A 1ME5A 2XE5A 3FYXA 4N58A 5B66O 2O4VA 4FT6A 2OYOA 2ZFGA 1S5LO 4IL6O 3AA0B 3WU2O 3PF1A 1GU9A 2Y0LA 3LK42 4AYID 4GHBA 2W80C 2GE4A 3NJTA 3AAEB 2KC0A 1MPFA 4O49A 4D5UA 3T24A 4Z3TA 5ADXK 2PRRA 2XE1A 3PGUA 1BT9A 2ES9A 3QRAA 3EMNX 1BXWA 1Q9GA 2JN8A 4KR8A 2KXPA 3BEYA 4FESA 1T16A 4K3BA 4O3ZA 3SZVA 4AKRA 3PQUA 3T0SA 4C00A 4K3CA 1GFQA 4D65A 1QJPA 3TZGA 1KNCA 5KAIO 2YNKA 3AA6B 3G7GA 2N2MA 3HOLA 3A0BO 7PRNA 5B5EO 1ZHWA 5E79O 5FVNA 5G38A 2XG6A 1LW1A 2O4DA 3AA7B 3AA0A 2JMMA 1OSMA 1MM4A 2XE2A 4GCPA 2F1TA 3AAEA 2M06A 4RJWA 2X27X 1GFNA 5DIPA 4U9CA 2WVPA 4C4VA 4QQ1A 3JCUO 2M07A 4B61A 5G3AA 4FMSA 1YS5A 3DA4A 2OUWA 4AUIA 2R88A 4JFBA 2WJRA 4KRAA 2IWVA 1THQA 3LK2B 2R4LA 3T20A 3LK3B 2J4UP 4UB6O 1ZHYA 3C1LA 4N74A 1PRNA 5AFUK 4LSEA 5AFUL 3VZWX 3AA1B 4PUXA 4E1TA 5JDPA 4FQEA 1HXXA 4FZLA 2N2LA 1GFOA 3VZUX 3HWBA 2R4OA 3AA7A 3LK41 2J1NA 3BS0A 4RL9A 4AZLA 5ADXL 2FGQX 2PRNA 3POQA 2Y7SA 4RLBA 4E1SA 4AYNA 2ODJA 1T1LA 1QJ9A 2WJQA 2K0LA 2R4PA 3D7IA 3WI5A 5DL7A 1P8CA 2Q0TA 4F4BA 4FUVA 4O3WA 3LVYA 2LFUA 2F1CX 3PRNA 4AFKA 4FSOA 2AXTO 4FZMA 4JCHA 3GP6A 4FSPA 3SZDA
chains in the Genus database with same CATH topology
2OYOA 2W81C 1GFNA 4BUMX 5DIPA 4U9CA 3V8UA 3VY8X 2ZFGA 1BH3A 5DL6A 3LK2A 2XTQA 2Y0KA 4QQ1A 3LK3A 3VE1A 2LHFA 2M07A 1GFMA 3AA0B 3PQSA 4B61A 3AAAB 5T5FA 5DL5A 4FZNA 4FMSA 4LSIA 4FRXA 1GU9A 1ZHXA 2Y0LA 1MM5A 2XMXA 3LK42 3VZTX 4JCHA 4AYID 1GFPA 1ORMA 1YS5A 1ZHTA 3QRCA 4GHBA 3AA1A 2W80C 5IYUA 2GE4A 3O0EA 1E54A 5DL8A 3RBHA 3DA4A 3AAEB 2KC0A 4AYEC 2OUWA 1MPFA 4O49A 4AUIA 4D5UA 2YPVA 4JFBA 2GMYA 1ZHZA 3HW9A 4AYDC 4O3XB 2QEUA 3T24A 4KRAA 4Z3TA 2AF7A 3DA3A 2IJCA 1THQA 3LK2B 5ADXK 4G75A 3T20A 2PRRA 1HXTA 2CWQA 2XE1A 3LK3B 4GCQA 5D5DA 2PORA 2KZ7A 1BT9A 2ES9A 1ZHYA 3QRAA 4GF4A 2J4UP 3C1LA 1PRNA 4G76A 5AFUK 4O4XA 1QJ8A 2MNHA 4LSEA 3EMNX 5G26A 1BXWA 5AFUL 1Q9GA 8PRNA 2ERVA 2JN8A 3C5OA 3GP6A 3VZWX 5GV0A 4KR8A 3AA1B 2Y2XA 2KXPA 4PUXA 3BEYA 4FESA 4E1TA 2OMFA 3NSGA 2MHLA 5JDPA 5EE2A 3SY7A 4O3ZA 3SZVA 4GCSA 4LSHA 4AKRA 3PQUA 3UPGA 3KVDD 3T0SA 1P4TA 1HXXA 2KDYA 4FZLA 1H6S1 2XTRA 3VY9X 2N2LA 1GFOA 1IZNA 4O4UA 3VZUX 3HWBA 2FGRA 2Y0HA 3AA7A 3LK41 2J1NA 4RL9A 5DIKA 2KZ7B 4AZLA 1GFQA 5ADXL 3A2SX 2FGQX 2PRNA 3JTYA 3PORA 3POQA 4G9QA 1QJPA 4D65A 1G90A 2Y7SA 4FOZA 3TZGA 1KNCA 2K4TA 4RLBA 3K19A 4E1SA 2F1VA 4XNLA 2YNKA 3AA6B 4XNKA 5PRNA 1OPFA 2KXPB 3AA6A 3SYSA 3G7GA 4AYNA 4D64A 2ODJA 2N2MA 3VE2A 3HOLA 3UAQA 3HOEA 2ZLDA 1HXUA 1QJ9A 4AKMA 4AKRB 7PRNA 4C69X 3SY9A 4FRTA 3WI4A 2PFXA 1ZHWA 4KR4A 5FVNA 4LSFA 6PRNA 1IZNB 2XE3A 2XG6A 3SYBA 1LW1A 2K0LA 3D7IA 3POUA 2O4DA 3AA7B 5DL7A 3AA0A 1PHOA 2JMMA 3WI5A 1P8CA 4RLCA 2Q0TA 4N59A 3UU2A 3AAAA 1OSMA 4F4BA 4O3YA 1ME5A 2XE5A 3FYXA 4FUVA 4O3WA 4RJXA 3LVYA 4RJWA 4N58A 4AYMC 1MM4A 2LFUA 2XE2A 3POXA 2QTKA 3PRNA 1Q9FA 4AFKA 4GCPA 4FSOA 2F1TA 2O4VA 1VKEA 4FZMA 3AAEA 2M06A 4FSPA 2X27X 3SZDA 4FT6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AKR A;  4AKR B;  1IZN A;  1IZN B;  3LK2 A;  3LK2 B;  5ADX K;  3LK3 A;  3LK3 B;  3AA7 A;  3LK4 1;  3AA7 B;  3AA0 A;  2KZ7 A;  2KZ7 B;  3AA0 B;  3AAA A;  3AAA B;  5ADX L;  5AFU K;  3LK4 2;  5AFU L;  3AA1 A;  3AA1 B;  3AA6 B;  2KXP A;  2KXP B;  3AA6 A;  3AAE A;  3AAE B; 
#chains in the Genus database with same CATH topology
 2W81 C;  5G39 A;  5GTI O;  3V8U A;  5H2F O;  5DL6 A;  3A0H O;  3LK2 A;  2XTQ A;  2Y0K A;  3LK3 A;  3VE1 A;  1GFM A;  5KAF O;  3AAA B;  5T5F A;  5DL5 A;  4FZN A;  4LSI A;  4FRX A;  2IWW A;  1MM5 A;  1GFP A;  1ORM A;  3KZI O;  2R8A A;  3AA1 A;  3O0E A;  1E54 A;  4AYE C;  3HW9 A;  3PGS A;  2QEU A;  2AF7 A;  3DA3 A;  2IJC A;  5TIS O;  1HXT A;  4GCQ A;  2POR A;  4GF4 A;  4G76 A;  1QJ8 A;  5G26 A;  3C5O A;  5GV0 A;  2OMF A;  3NSG A;  5EE2 A;  4GCS A;  3BRY A;  3UPG A;  1P4T A;  2KDY A;  2XTR A;  3VY9 X;  4O4U A;  2KZ7 B;  3POR A;  3DWN A;  4G9Q A;  3K19 A;  5GTH O;  4XNL A;  4XNK A;  5PRN A;  3AA6 A;  4D64 A;  3VE2 A;  2ZLD A;  4CTD A;  4AKM A;  4C69 X;  3SY9 A;  4FRT A;  2PFX A;  6PRN A;  1IZN B;  2XE3 A;  3POU A;  1PHO A;  3UU2 A;  3AAA A;  4O3Y A;  2X9K A;  4RJX A;  4AYM C;  3POX A;  2QTK A;  1Q9F A;  1VKE A;  3DWO X;  3PGR A;  4BUM X;  3VY8 X;  1BH3 A;  4C4V B;  2LHF A;  3PQS A;  1ZHX A;  3VZT X;  2XMX A;  1ZHT A;  3QRC A;  5IYU A;  5DL8 A;  3RBH A;  3DZM A;  2YPV A;  2GMY A;  1ZHZ A;  4AYD C;  4O3X B;  4UB8 O;  4G75 A;  2CWQ A;  5D5D A;  2KZ7 A;  4O4X A;  2MNH A;  4PR7 A;  8PRN A;  2ERV A;  2Y2X A;  2MHL A;  3SY7 A;  4LSH A;  3KVD D;  1H6S 1;  1IZN A;  2FGR A;  2Y0H A;  4N75 A;  5DIK A;  3BRZ A;  3A2S X;  3JTY A;  1G90 A;  4PJ0 O;  4FOZ A;  2K4T A;  2F1V A;  3SYS A;  1OPF A;  2KXP B;  3UAQ A;  3HOE A;  1HXU A;  2JQY A;  4AKR B;  3WI4 A;  2R4N A;  4KR4 A;  4LSF A;  3SYB A;  4RLC A;  4N59 A;  2R89 A;  1ME5 A;  2XE5 A;  3FYX A;  4N58 A;  5B66 O;  2O4V A;  4FT6 A;  2OYO A;  2ZFG A;  1S5L O;  4IL6 O;  3AA0 B;  3WU2 O;  3PF1 A;  1GU9 A;  2Y0L A;  3LK4 2;  4AYI D;  4GHB A;  2W80 C;  2GE4 A;  3NJT A;  3AAE B;  2KC0 A;  1MPF A;  4O49 A;  4D5U A;  3T24 A;  4Z3T A;  5ADX K;  2PRR A;  2XE1 A;  3PGU A;  1BT9 A;  2ES9 A;  3QRA A;  3EMN X;  1BXW A;  1Q9G A;  2JN8 A;  4KR8 A;  2KXP A;  3BEY A;  4FES A;  1T16 A;  4K3B A;  4O3Z A;  3SZV A;  4AKR A;  3PQU A;  3T0S A;  4C00 A;  4K3C A;  1GFQ A;  4D65 A;  1QJP A;  3TZG A;  1KNC A;  5KAI O;  2YNK A;  3AA6 B;  3G7G A;  2N2M A;  3HOL A;  3A0B O;  7PRN A;  5B5E O;  1ZHW A;  5E79 O;  5FVN A;  5G38 A;  2XG6 A;  1LW1 A;  2O4D A;  3AA7 B;  3AA0 A;  2JMM A;  1OSM A;  1MM4 A;  2XE2 A;  4GCP A;  2F1T A;  3AAE A;  2M06 A;  4RJW A;  2X27 X;  1GFN A;  5DIP A;  4U9C A;  2WVP A;  4C4V A;  4QQ1 A;  3JCU O;  2M07 A;  4B61 A;  5G3A A;  4FMS A;  1YS5 A;  3DA4 A;  2OUW A;  4AUI A;  2R88 A;  4JFB A;  2WJR A;  4KRA A;  2IWV A;  1THQ A;  3LK2 B;  2R4L A;  3T20 A;  3LK3 B;  2J4U P;  4UB6 O;  1ZHY A;  3C1L A;  4N74 A;  1PRN A;  5AFU K;  4LSE A;  5AFU L;  3VZW X;  3AA1 B;  4PUX A;  4E1T A;  5JDP A;  4FQE A;  1HXX A;  4FZL A;  2N2L A;  1GFO A;  3VZU X;  3HWB A;  2R4O A;  3AA7 A;  3LK4 1;  2J1N A;  3BS0 A;  4RL9 A;  4AZL A;  5ADX L;  2FGQ X;  2PRN A;  3POQ A;  2Y7S A;  4RLB A;  4E1S A;  4AYN A;  2ODJ A;  1T1L A;  1QJ9 A;  2WJQ A;  2K0L A;  2R4P A;  3D7I A;  3WI5 A;  5DL7 A;  1P8C A;  2Q0T A;  4F4B A;  4FUV A;  4O3W A;  3LVY A;  2LFU A;  2F1C X;  3PRN A;  4AFK A;  4FSO A;  2AXT O;  4FZM A;  4JCH A;  3GP6 A;  4FSP A;  3SZD A; 
#chains in the Genus database with same CATH homology
 2OYO A;  2W81 C;  1GFN A;  4BUM X;  5DIP A;  4U9C A;  3V8U A;  3VY8 X;  2ZFG A;  1BH3 A;  5DL6 A;  3LK2 A;  2XTQ A;  2Y0K A;  4QQ1 A;  3LK3 A;  3VE1 A;  2LHF A;  2M07 A;  1GFM A;  3AA0 B;  3PQS A;  4B61 A;  3AAA B;  5T5F A;  5DL5 A;  4FZN A;  4FMS A;  4LSI A;  4FRX A;  1GU9 A;  1ZHX A;  2Y0L A;  1MM5 A;  2XMX A;  3LK4 2;  3VZT X;  4JCH A;  4AYI D;  1GFP A;  1ORM A;  1YS5 A;  1ZHT A;  3QRC A;  4GHB A;  3AA1 A;  2W80 C;  5IYU A;  2GE4 A;  3O0E A;  1E54 A;  5DL8 A;  3RBH A;  3DA4 A;  3AAE B;  2KC0 A;  4AYE C;  2OUW A;  1MPF A;  4O49 A;  4AUI A;  4D5U A;  2YPV A;  4JFB A;  2GMY A;  1ZHZ A;  3HW9 A;  4AYD C;  4O3X B;  2QEU A;  3T24 A;  4KRA A;  4Z3T A;  2AF7 A;  3DA3 A;  2IJC A;  1THQ A;  3LK2 B;  5ADX K;  4G75 A;  3T20 A;  2PRR A;  1HXT A;  2CWQ A;  2XE1 A;  3LK3 B;  4GCQ A;  5D5D A;  2POR A;  2KZ7 A;  1BT9 A;  2ES9 A;  1ZHY A;  3QRA A;  4GF4 A;  2J4U P;  3C1L A;  1PRN A;  4G76 A;  5AFU K;  4O4X A;  1QJ8 A;  2MNH A;  4LSE A;  3EMN X;  5G26 A;  1BXW A;  5AFU L;  1Q9G A;  8PRN A;  2ERV A;  2JN8 A;  3C5O A;  3GP6 A;  3VZW X;  5GV0 A;  4KR8 A;  3AA1 B;  2Y2X A;  2KXP A;  4PUX A;  3BEY A;  4FES A;  4E1T A;  2OMF A;  3NSG A;  2MHL A;  5JDP A;  5EE2 A;  3SY7 A;  4O3Z A;  3SZV A;  4GCS A;  4LSH A;  4AKR A;  3PQU A;  3UPG A;  3KVD D;  3T0S A;  1P4T A;  1HXX A;  2KDY A;  4FZL A;  1H6S 1;  2XTR A;  3VY9 X;  2N2L A;  1GFO A;  1IZN A;  4O4U A;  3VZU X;  3HWB A;  2FGR A;  2Y0H A;  3AA7 A;  3LK4 1;  2J1N A;  4RL9 A;  5DIK A;  2KZ7 B;  4AZL A;  1GFQ A;  5ADX L;  3A2S X;  2FGQ X;  2PRN A;  3JTY A;  3POR A;  3POQ A;  4G9Q A;  1QJP A;  4D65 A;  1G90 A;  2Y7S A;  4FOZ A;  3TZG A;  1KNC A;  2K4T A;  4RLB A;  3K19 A;  4E1S A;  2F1V A;  4XNL A;  2YNK A;  3AA6 B;  4XNK A;  5PRN A;  1OPF A;  2KXP B;  3AA6 A;  3SYS A;  3G7G A;  4AYN A;  4D64 A;  2ODJ A;  2N2M A;  3VE2 A;  3HOL A;  3UAQ A;  3HOE A;  2ZLD A;  1HXU A;  1QJ9 A;  4AKM A;  4AKR B;  7PRN A;  4C69 X;  3SY9 A;  4FRT A;  3WI4 A;  2PFX A;  1ZHW A;  4KR4 A;  5FVN A;  4LSF A;  6PRN A;  1IZN B;  2XE3 A;  2XG6 A;  3SYB A;  1LW1 A;  2K0L A;  3D7I A;  3POU A;  2O4D A;  3AA7 B;  5DL7 A;  3AA0 A;  1PHO A;  2JMM A;  3WI5 A;  1P8C A;  4RLC A;  2Q0T A;  4N59 A;  3UU2 A;  3AAA A;  1OSM A;  4F4B A;  4O3Y A;  1ME5 A;  2XE5 A;  3FYX A;  4FUV A;  4O3W A;  4RJX A;  3LVY A;  4RJW A;  4N58 A;  4AYM C;  1MM4 A;  2LFU A;  2XE2 A;  3POX A;  2QTK A;  3PRN A;  1Q9F A;  4AFK A;  4GCP A;  4FSO A;  2F1T A;  2O4V A;  1VKE A;  4FZM A;  3AAE A;  2M06 A;  4FSP A;  2X27 X;  3SZD A;  4FT6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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