5AFUK

Cryo-em structure of dynein tail-dynactin-bicd2n complex
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
275
structure length
275
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEVDGSLKSWRESCDSALRAYVKDHYSNGFCTVYAKNIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEAQTAKEFIKIIEHAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structure of the Dynactin Complex and its Interaction with Dynein.
pubmed doi rcsb
molecule tags Motor protein
molecule keywords DYNEIN TAIL
total genus 65
structure length 275
sequence length 275
ec nomenclature
pdb deposition date 2015-01-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 5afuK01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 5afuK02
5AFUL 3LK2B 4AKRA 3AA1A 5ADXL 2KXPA 5AFUK 3AAAB 3AA0A 1IZNA 3AA7B 2KZ7A 3AAEB 3AA6B 3LK3A 5ADXK 4AKRB 3LK2A 3AA1B 2KXPB 1IZNB 3AAAA 3AA7A 3AA0B 2KZ7B 3LK42 3AA6A 3LK41 3LK3B 3AAEA
chains in the Genus database with same CATH superfamily
4UB8O 5DL6A 1ME5A 3VZTX 2K4TA 2O4VA 7PRNA 4D64A 2XE2A 5ADXK 2AXTO 4LSEA 3A2SX 3PORA 2FGRA 4GCPA 1MM5A 1GFNA 4FZNA 6PRNA 4KR4A 1BH3A 2PORA 3AA1A 5ADXL 3DA4A 2M07A 4U9CA 4C00A 4PR7A 3PRNA 2OUWA 3DWNA 3PGUA 2JQYA 2XTRA 5G26A 2Y7SA 5DIKA 2X9KA 3VY9X 4FZMA 3PQUA 4LSIA 2R88A 3LK3B 2K0LA 4FSOA 4RLBA 2LHFA 4C4VA 3SZVA 3POUA 4O49A 2KXPA 3SY7A 3AA7B 2GMYA 5KAIO 3SYSA 3QRAA 5E79O 2QTKA 5KAFO 2FGQX 1S5LO 8PRNA 4O3XB 2CWQA 3JTYA 5B66O 2Y0LA 4GCQA 2XTQA 3AA0A 5FVNA 3HWBA 3VE2A 2MHLA 4G76A 2M06A 1BT9A 3SY9A 2R4OA 4O3ZA 4O3WA 4E1TA 3AAEA 5AFUL 2ODJA 3DA3A 1H6S1 2ERVA 1PRNA 3C1LA 1P4TA 4FESA 3AA6B 4PJ0O 2OMFA 1MPFA 2WJRA 1GFMA 4KR8A 5G39A 3DZMA 1PHOA 1ZHWA 5EE2A 1E54A 3A0BO 2XE1A 3T20A 3O0EA 2IWVA 2YPVA 4JCHA 1Q9FA 2OYOA 3SYBA 2ZLDA 4GHBA 1QJPA 3POXA 4N58A 1ZHYA 2IJCA 4AYDC 3BEYA 1IZNA 3HW9A 4FSPA 3NSGA 5DIPA 2XMXA 2AF7A 4AFKA 2W80C 3VZUX 3RBHA 1GFPA 2R8AA 4FT6A 4PUXA 2F1VA 4GF4A 1VKEA 1ORMA 3AAEB 4N59A 1BXWA 3WI5A 2KC0A 3KVDD 2JN8A 2Y0HA 2R4NA 3UAQA 5G38A 1Q9GA 3BRZA 4AKRA 3T24A 2PRNA 4N74A 1LW1A 2YNKA 5DL7A 2R4PA 2F1TA 4GCSA 2GE4A 3LK2A 4KRAA 4O3YA 1YS5A 3DWOX 4G75A 1OSMA 4FQEA 2WJQA 2QEUA 1OPFA 3PF1A 1T16A 4QQ1A 5TISO 1GU9A 2O4DA 2J4UP 4G9QA 3GP6A 4IL6O 4Z3TA 3T0SA 3AA1B 3UPGA 1THQA 1IZNB 3PQSA 3AA7A 2N2MA 3C5OA 2JMMA 1HXXA 3UU2A 4E1SA 1T1LA 3KZIO 4O4UA 5PRNA 4LSFA 4FUVA 1ZHXA 4C4VB 2KXPB 2Y2XA 3BRYA 4RL9A 3AAAA 2PRRA 4XNLA 4XNKA 5T5FA 3LK41 4D65A 2ES9A 3G7GA 2XG6A 4AYMC 3V8UA 2Y0KA 5DL5A 5GTIO 2KZ7A 4RJWA 3HOEA 2ZFGA 3BS0A 4LSHA 4AKRB 1ZHTA 4AYNA 2MNHA 4F4BA 3AA0B 3NJTA 5DL8A 3AA6A 3D7IA 1HXUA 2Q0TA 3LK2B 5D5DA 2R4LA 4AYEC 3A0HO 3JCUO 2XE3A 3QRCA 3VZWX 1HXTA 3WU2O 3K19A 5GTHO 2IWWA 4JFBA 4CTDA 3PGSA 4RLCA 2W81C 5JDPA 3FYXA 4BUMX 3LVYA 1ZHZA 2X27X 1QJ8A 2KDYA 5G3AA 2LFUA 3POQA 2F1CX 4B61A 4FRXA 1KNCA 4FOZA 2WVPA 5GV0A 1MM4A 1QJ9A 4AUIA 5AFUK 3AAAB 4D5UA 4K3BA 4AKMA 5H2FO 1GFQA 3LK3A 3TZGA 2N2LA 1G90A 3PGRA 2R89A 5B5EO 4O4XA 3LK42 2KZ7B 4K3CA 4FMSA 1P8CA 2PFXA 4UB6O 2XE5A 2J1NA 1GFOA 3VY8X 4AZLA 4N75A 3EMNX 4FZLA 3WI4A 4FRTA 3VE1A 3HOLA 4RJXA 4C69X 5IYUA 3SZDA 4AYID
chains in the Genus database with same CATH topology
5AFUL 1Q9GA 2Q0TA 3LK2B 2ODJA 4AKRA 5D5DA 5DL6A 3DA3A 2PRNA 3T24A 1H6S1 2ERVA 4AYEC 1ME5A 3VZTX 1PRNA 2K4TA 2O4VA 1LW1A 3C1LA 7PRNA 1P4TA 2XE3A 4D64A 3QRCA 3VZWX 2YNKA 4FESA 1HXTA 5DL7A 3AA6B 3K19A 2F1TA 2XE2A 5ADXK 4GCSA 2OMFA 1MPFA 2GE4A 3LK2A 4LSEA 3A2SX 1GFMA 3PORA 2FGRA 4KRAA 4O3YA 4JFBA 4GCPA 4RLCA 1MM5A 4KR8A 1YS5A 1GFNA 4FZNA 6PRNA 4KR4A 2W81C 1PHOA 5JDPA 4G75A 1BH3A 1ZHWA 1OSMA 2PORA 3FYXA 4BUMX 3LVYA 1ZHZA 3AA6A 5EE2A 2X27X 2QEUA 3AA1A 5ADXL 1OPFA 4QQ1A 3DA4A 1GU9A 1QJ8A 2M07A 2KDYA 4U9CA 2O4DA 1E54A 2XE1A 3T20A 3O0EA 3PRNA 2OUWA 2LFUA 2J4UP 4G9QA 2YPVA 4JCHA 2XTRA 1Q9FA 3POQA 5G26A 3GP6A 4B61A 4Z3TA 4FRXA 2Y7SA 3T0SA 2OYOA 5DIKA 3SYBA 3AA1B 2ZLDA 3VY9X 1KNCA 4FOZA 4GHBA 3UPGA 1THQA 4FZMA 1IZNB 3PQUA 3PQSA 3AA7A 5GV0A 1QJPA 2N2MA 3C5OA 4LSIA 2JMMA 1MM4A 1QJ9A 4AYID 1HXXA 3LK3B 3POXA 2K0LA 4FSOA 4N58A 3UU2A 4RLBA 2LHFA 3SZVA 3POUA 4E1SA 4O49A 2KXPA 1ZHYA 3SY7A 4AUIA 2IJCA 4AYDC 3BEYA 5AFUK 3AAAB 4O4UA 1IZNA 3HW9A 5PRNA 4FSPA 3NSGA 4D5UA 3AA7B 2GMYA 5DIPA 4LSFA 4AKMA 1GFQA 3LK3A 2XMXA 3TZGA 3SYSA 2AF7A 4FUVA 1ZHXA 2N2LA 3QRAA 2QTKA 4AFKA 1G90A 2FGQX 2W80C 2KXPB 2Y2XA 4RL9A 8PRNA 4O3XB 2CWQA 3JTYA 4O4XA 3AAAA 3LK42 2KZ7B 3VZUX 4FMSA 2PRRA 4XNLA 1P8CA 4XNKA 2Y0LA 3LK41 5T5FA 3RBHA 2PFXA 1GFPA 2ES9A 4D65A 3G7GA 4FT6A 4PUXA 2XG6A 4GCQA 3V8UA 2F1VA 4AYMC 2XTQA 2XE5A 4GF4A 1VKEA 2J1NA 1GFOA 1ORMA 2Y0KA 5DL5A 3AA0A 5FVNA 2KZ7A 3VY8X 3HWBA 4RJWA 3HOEA 4AZLA 3EMNX 3AAEB 4FZLA 4N59A 3VE2A 1BXWA 2ZFGA 4LSHA 3WI4A 4AKRB 1ZHTA 2MHLA 4G76A 3WI5A 2KC0A 3KVDD 4FRTA 2M06A 4AYNA 3VE1A 1BT9A 2JN8A 3SY9A 2Y0HA 2MNHA 4F4BA 3HOLA 4O3ZA 3UAQA 3AA0B 4RJXA 4C69X 5DL8A 5IYUA 4O3WA 3SZDA 3D7IA 4E1TA 1HXUA 3AAEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AFU L;  3LK2 B;  4AKR A;  3AA1 A;  5ADX L;  2KXP A;  5AFU K;  3AAA B;  3AA0 A;  1IZN A;  3AA7 B;  2KZ7 A;  3AAE B;  3AA6 B;  3LK3 A;  5ADX K;  4AKR B;  3LK2 A;  3AA1 B;  2KXP B;  1IZN B;  3AAA A;  3AA7 A;  3AA0 B;  2KZ7 B;  3LK4 2;  3AA6 A;  3LK4 1;  3LK3 B;  3AAE A; 
#chains in the Genus database with same CATH topology
 4UB8 O;  5DL6 A;  1ME5 A;  3VZT X;  2K4T A;  2O4V A;  7PRN A;  4D64 A;  2XE2 A;  5ADX K;  2AXT O;  4LSE A;  3A2S X;  3POR A;  2FGR A;  4GCP A;  1MM5 A;  1GFN A;  4FZN A;  6PRN A;  4KR4 A;  1BH3 A;  2POR A;  3AA1 A;  5ADX L;  3DA4 A;  2M07 A;  4U9C A;  4C00 A;  4PR7 A;  3PRN A;  2OUW A;  3DWN A;  3PGU A;  2JQY A;  2XTR A;  5G26 A;  2Y7S A;  5DIK A;  2X9K A;  3VY9 X;  4FZM A;  3PQU A;  4LSI A;  2R88 A;  3LK3 B;  2K0L A;  4FSO A;  4RLB A;  2LHF A;  4C4V A;  3SZV A;  3POU A;  4O49 A;  2KXP A;  3SY7 A;  3AA7 B;  2GMY A;  5KAI O;  3SYS A;  3QRA A;  5E79 O;  2QTK A;  5KAF O;  2FGQ X;  1S5L O;  8PRN A;  4O3X B;  2CWQ A;  3JTY A;  5B66 O;  2Y0L A;  4GCQ A;  2XTQ A;  3AA0 A;  5FVN A;  3HWB A;  3VE2 A;  2MHL A;  4G76 A;  2M06 A;  1BT9 A;  3SY9 A;  2R4O A;  4O3Z A;  4O3W A;  4E1T A;  3AAE A;  5AFU L;  2ODJ A;  3DA3 A;  1H6S 1;  2ERV A;  1PRN A;  3C1L A;  1P4T A;  4FES A;  3AA6 B;  4PJ0 O;  2OMF A;  1MPF A;  2WJR A;  1GFM A;  4KR8 A;  5G39 A;  3DZM A;  1PHO A;  1ZHW A;  5EE2 A;  1E54 A;  3A0B O;  2XE1 A;  3T20 A;  3O0E A;  2IWV A;  2YPV A;  4JCH A;  1Q9F A;  2OYO A;  3SYB A;  2ZLD A;  4GHB A;  1QJP A;  3POX A;  4N58 A;  1ZHY A;  2IJC A;  4AYD C;  3BEY A;  1IZN A;  3HW9 A;  4FSP A;  3NSG A;  5DIP A;  2XMX A;  2AF7 A;  4AFK A;  2W80 C;  3VZU X;  3RBH A;  1GFP A;  2R8A A;  4FT6 A;  4PUX A;  2F1V A;  4GF4 A;  1VKE A;  1ORM A;  3AAE B;  4N59 A;  1BXW A;  3WI5 A;  2KC0 A;  3KVD D;  2JN8 A;  2Y0H A;  2R4N A;  3UAQ A;  5G38 A;  1Q9G A;  3BRZ A;  4AKR A;  3T24 A;  2PRN A;  4N74 A;  1LW1 A;  2YNK A;  5DL7 A;  2R4P A;  2F1T A;  4GCS A;  2GE4 A;  3LK2 A;  4KRA A;  4O3Y A;  1YS5 A;  3DWO X;  4G75 A;  1OSM A;  4FQE A;  2WJQ A;  2QEU A;  1OPF A;  3PF1 A;  1T16 A;  4QQ1 A;  5TIS O;  1GU9 A;  2O4D A;  2J4U P;  4G9Q A;  3GP6 A;  4IL6 O;  4Z3T A;  3T0S A;  3AA1 B;  3UPG A;  1THQ A;  1IZN B;  3PQS A;  3AA7 A;  2N2M A;  3C5O A;  2JMM A;  1HXX A;  3UU2 A;  4E1S A;  1T1L A;  3KZI O;  4O4U A;  5PRN A;  4LSF A;  4FUV A;  1ZHX A;  4C4V B;  2KXP B;  2Y2X A;  3BRY A;  4RL9 A;  3AAA A;  2PRR A;  4XNL A;  4XNK A;  5T5F A;  3LK4 1;  4D65 A;  2ES9 A;  3G7G A;  2XG6 A;  4AYM C;  3V8U A;  2Y0K A;  5DL5 A;  5GTI O;  2KZ7 A;  4RJW A;  3HOE A;  2ZFG A;  3BS0 A;  4LSH A;  4AKR B;  1ZHT A;  4AYN A;  2MNH A;  4F4B A;  3AA0 B;  3NJT A;  5DL8 A;  3AA6 A;  3D7I A;  1HXU A;  2Q0T A;  3LK2 B;  5D5D A;  2R4L A;  4AYE C;  3A0H O;  3JCU O;  2XE3 A;  3QRC A;  3VZW X;  1HXT A;  3WU2 O;  3K19 A;  5GTH O;  2IWW A;  4JFB A;  4CTD A;  3PGS A;  4RLC A;  2W81 C;  5JDP A;  3FYX A;  4BUM X;  3LVY A;  1ZHZ A;  2X27 X;  1QJ8 A;  2KDY A;  5G3A A;  2LFU A;  3POQ A;  2F1C X;  4B61 A;  4FRX A;  1KNC A;  4FOZ A;  2WVP A;  5GV0 A;  1MM4 A;  1QJ9 A;  4AUI A;  5AFU K;  3AAA B;  4D5U A;  4K3B A;  4AKM A;  5H2F O;  1GFQ A;  3LK3 A;  3TZG A;  2N2L A;  1G90 A;  3PGR A;  2R89 A;  5B5E O;  4O4X A;  3LK4 2;  2KZ7 B;  4K3C A;  4FMS A;  1P8C A;  2PFX A;  4UB6 O;  2XE5 A;  2J1N A;  1GFO A;  3VY8 X;  4AZL A;  4N75 A;  3EMN X;  4FZL A;  3WI4 A;  4FRT A;  3VE1 A;  3HOL A;  4RJX A;  4C69 X;  5IYU A;  3SZD A;  4AYI D; 
#chains in the Genus database with same CATH homology
 5AFU L;  1Q9G A;  2Q0T A;  3LK2 B;  2ODJ A;  4AKR A;  5D5D A;  5DL6 A;  3DA3 A;  2PRN A;  3T24 A;  1H6S 1;  2ERV A;  4AYE C;  1ME5 A;  3VZT X;  1PRN A;  2K4T A;  2O4V A;  1LW1 A;  3C1L A;  7PRN A;  1P4T A;  2XE3 A;  4D64 A;  3QRC A;  3VZW X;  2YNK A;  4FES A;  1HXT A;  5DL7 A;  3AA6 B;  3K19 A;  2F1T A;  2XE2 A;  5ADX K;  4GCS A;  2OMF A;  1MPF A;  2GE4 A;  3LK2 A;  4LSE A;  3A2S X;  1GFM A;  3POR A;  2FGR A;  4KRA A;  4O3Y A;  4JFB A;  4GCP A;  4RLC A;  1MM5 A;  4KR8 A;  1YS5 A;  1GFN A;  4FZN A;  6PRN A;  4KR4 A;  2W81 C;  1PHO A;  5JDP A;  4G75 A;  1BH3 A;  1ZHW A;  1OSM A;  2POR A;  3FYX A;  4BUM X;  3LVY A;  1ZHZ A;  3AA6 A;  5EE2 A;  2X27 X;  2QEU A;  3AA1 A;  5ADX L;  1OPF A;  4QQ1 A;  3DA4 A;  1GU9 A;  1QJ8 A;  2M07 A;  2KDY A;  4U9C A;  2O4D A;  1E54 A;  2XE1 A;  3T20 A;  3O0E A;  3PRN A;  2OUW A;  2LFU A;  2J4U P;  4G9Q A;  2YPV A;  4JCH A;  2XTR A;  1Q9F A;  3POQ A;  5G26 A;  3GP6 A;  4B61 A;  4Z3T A;  4FRX A;  2Y7S A;  3T0S A;  2OYO A;  5DIK A;  3SYB A;  3AA1 B;  2ZLD A;  3VY9 X;  1KNC A;  4FOZ A;  4GHB A;  3UPG A;  1THQ A;  4FZM A;  1IZN B;  3PQU A;  3PQS A;  3AA7 A;  5GV0 A;  1QJP A;  2N2M A;  3C5O A;  4LSI A;  2JMM A;  1MM4 A;  1QJ9 A;  4AYI D;  1HXX A;  3LK3 B;  3POX A;  2K0L A;  4FSO A;  4N58 A;  3UU2 A;  4RLB A;  2LHF A;  3SZV A;  3POU A;  4E1S A;  4O49 A;  2KXP A;  1ZHY A;  3SY7 A;  4AUI A;  2IJC A;  4AYD C;  3BEY A;  5AFU K;  3AAA B;  4O4U A;  1IZN A;  3HW9 A;  5PRN A;  4FSP A;  3NSG A;  4D5U A;  3AA7 B;  2GMY A;  5DIP A;  4LSF A;  4AKM A;  1GFQ A;  3LK3 A;  2XMX A;  3TZG A;  3SYS A;  2AF7 A;  4FUV A;  1ZHX A;  2N2L A;  3QRA A;  2QTK A;  4AFK A;  1G90 A;  2FGQ X;  2W80 C;  2KXP B;  2Y2X A;  4RL9 A;  8PRN A;  4O3X B;  2CWQ A;  3JTY A;  4O4X A;  3AAA A;  3LK4 2;  2KZ7 B;  3VZU X;  4FMS A;  2PRR A;  4XNL A;  1P8C A;  4XNK A;  2Y0L A;  3LK4 1;  5T5F A;  3RBH A;  2PFX A;  1GFP A;  2ES9 A;  4D65 A;  3G7G A;  4FT6 A;  4PUX A;  2XG6 A;  4GCQ A;  3V8U A;  2F1V A;  4AYM C;  2XTQ A;  2XE5 A;  4GF4 A;  1VKE A;  2J1N A;  1GFO A;  1ORM A;  2Y0K A;  5DL5 A;  3AA0 A;  5FVN A;  2KZ7 A;  3VY8 X;  3HWB A;  4RJW A;  3HOE A;  4AZL A;  3EMN X;  3AAE B;  4FZL A;  4N59 A;  3VE2 A;  1BXW A;  2ZFG A;  4LSH A;  3WI4 A;  4AKR B;  1ZHT A;  2MHL A;  4G76 A;  3WI5 A;  2KC0 A;  3KVD D;  4FRT A;  2M06 A;  4AYN A;  3VE1 A;  1BT9 A;  2JN8 A;  3SY9 A;  2Y0H A;  2MNH A;  4F4B A;  3HOL A;  4O3Z A;  3UAQ A;  3AA0 B;  4RJX A;  4C69 X;  5DL8 A;  5IYU A;  4O3W A;  3SZD A;  3D7I A;  4E1T A;  1HXU A;  3AAE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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