1MPGA

3-methyladenine dna glycosylase ii from escherichia coli
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
282
structure length
282
Chain Sequence
MYTLNWQPPYDWSWMLGFLAARAVSSVETVADSYYARSLAVGEYRGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGRLGAARPGLRLPGCVDAFEQGVRAILGQLVSVAMAAKLTARVAQLYGERLDDFPEYICFPTPQRLAAADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRWTANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEGWQPDEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the excision repair of alkylation-damaged DNA.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords 3-METHYLADENINE DNA GLYCOSYLASE II
total genus 92
structure length 282
sequence length 282
chains with identical sequence B
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 1997-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF06029 AlkA_N AlkA N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1mpgA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1mpgA03
3.30.310.20 Alpha Beta 2-Layer Sandwich TATA-Binding Protein DNA-3-methyladenine glycosylase AlkA, N-terminal domain 1mpgA01
1YQKA 3FHGA 1LWWA 4UOBA 1WEGA 3FHFA 4YPRA 1KG7A 3OH9A 4B24A 4EJYA 2NOFA 3CW7A 1N3CA 2OFKA 1RRSA 4YOQA 3D4VA 1KEAA 1MUNA 3KNTA 1KO9A 3IHOA 1N3AA 4HSBA 1DIZA 4DK9A 4B22A 4EA5A 1MPGA 3OGDA 4AI5A 1NGNA 1PU8A 4YPHA 4PIIA 1MUDA 4E9HA 2OFIA 1KG6A 2JHNA 2YG9A 1KG4A 5CHZA 3I0WA 5DPKA 4OFEA 1PVSA 3CWAA 4EA4A 4EW4A 1M3HA 4EVVA 1VRLA 1KQJA 3CWTA 4B21A 1HU0A 3N5NX 1EBMA 5KN9A 4OFHA 4EW0A 3F0ZA 1YQLA 4E9EA 3CWUA 1PU7A 3CWSA 1XG7A 5AN4A 2XHIA 4OFAA 3F10A 3N0UA 1YQMA 1ORNA 2NOHA 2I5WA 2NOBA 1KG5A 1YQRA 1KG2A 1FN7A 1LWVA 2YG8A 1XQOA 4UNFA 1N39A 4B23A 4EJZA 1WEFA 3IH7A 3CVSA 2NOEA 1P7MA 2JHJA 4AI4A 3KTUA 3CVTA 3G0QA 3OH6A 1P59A 1LWYA 4AIAA 1PU6A 1WEIA 1XQPA 2NOLA 2JG6A 4E9GA 2NOZA 4E9FA 1M3QA 1MUYA 3FSPA 3I0XA 1ORPA 5KN8A 2ABKA 1LMZA 1NKUA 2NOIA 1RRQA 3S6IA 1KG3A 2H56A
chains in the Genus database with same CATH superfamily
4UOBA 3FHFA 1KG7A 3EIKA 3ENCA 3CW7A 3ULXA 1RRSA 4YOQA 2FKFA 4D7RA 1J3MA 1MUNA 3KNTA 3PDKA 1QNEA 5EPCA 2IV9A 2H5AX 1K35A 1DIZA 3L2RA 4DK9A 3RSMA 3OYCA 2Y8QA 1MUDA 3S3NA 1TBPA 1UL7A 3OS2A 2DKAA 2YG9A 2DKCA 1KG4A 1QN7A 1KY6A 3S3MA 5DPKA 1PVSA 3N89A 4EA4A 4EW4A 2V8QA 4TPSA 4IL8A 1W80A 2QRDA 2PWWA 2HZSA 1PZDA 1HU0A 3OYNA 3L2UA 5KN9A 4C7PA 4EW0A 1JFIC 4E7KA 3CWUA 1XG7A 2HZMA 3OLPA 1ORNA 2NOHA 1KG5A 1YQRA 5FRMA 1N39A 2JPSA 5JMVD 4Q11A 2V9JA 2NVMA 4BE2A 3C04A 2FKMX 1MP9A 1R4XA 3LCNA 3HS9A 4IKFA 3H1ZA 2MZ8A 2V92A 2Z0FA 2D0CA 4WX8A 3SNSA 1D3UA 1XQPA 4E7JA 2NOZA 3I0XA 1ORPA 2ABKA 1LMZA 1KYFA 5BMPA 1PCMX 3VN5A 2D0BA 3I3WA 5IYDP 2O3OA 1RRQA 1RM1A 3FHGA 1WEGA 4YPRA 1LXTA 3NA5A 1PCJX 3OYFA 5F9CA 1VTLE 3D4VA 1KO9A 3IHOA 1MPGA 3OYMA 1NVPA 2HL9A 2F7LA 4PIIA 1QN4A 3OC3C 1KYDA 3BKQX 1P5DX 3RPJA 4EAGA 5FRNA 1Q9UA 3CWAA 3TE5A 1M3HA 4EVVA 1KQJA 3N5NX 1UT7A 4EAIA 3CWSA 1KFQA 5HSHA 4EALA 1NGMA 3OS1A 3VW4A 2Z8UA 1QN6A 1KG2A 1FN7A 3OSTA 1LWVA 4BDZA 2YG8A 4EAKA 3T4NA 1XQOA 1PCZA 1WEFA 5IYCP 3CVSA 2EHBD 2JHJA 4AI4A 5BMNA 1VTOA 2W03A 2NWVA 1LWYA 1PU6A 3L2WA 2NOLA 2MJ7A 4E9FA 4WZSD 5KN8A 1KYUA 1C4GA 3S6IA 3OYJA 1YQKA 1LWWA 4BE0A 4CFFA 4MRQA 3OH9A 1B9KA 3R2XC 4EJYA 1N3CA 2OFKA 1XSZA 1CDWA 1AISA 1KY7A 3OSMA 2YH5A 2DKDA 5JN5A 3KRMA 2D0AA 1VKLA 2JPIA 1QN3A 4EA5A 3S3OA 2H4LX 4AI5A 2FGTA 1PU8A 1WQAA 4YPHA 2QR1A 4BE1A 1KG6A 1NH2A 5CHZA 4E7HA 1TUOA 4OFEA 3OYGA 1VRLA 1QNBA 3TDHA 2OOXA 2VJ0A 1C47A 1QNCA 1EBMA 3PMGA 2Y8LA 3F0ZA 4E9EA 1PU7A 4B0AA 4BACA 5AN4A 1M5Q1 2XHIA 3D7QA 4OFAA 2ZFDB 3F10A 3N0UA 1YQMA 1QN9A 1QTSA 2I5WA 2NOBA 3OYDA 4B23A 2QRCA 1KFIA 3OYEA 3IH7A 3OY9A 2NOEA 2QREA 1P7MA 5IYBP 2IV8A 3NNQA 3KTUA 2QLVA 3CVTA 1QNAA 1WEIA 1VOKA 4E7IA 3OYAA 1P5GX 4E9GA 1MUYA 1NKUA 1K2YX 1KG3A 2H56A 3DPUA 4E7LA 4BJUA 1QN8A 3OYBA 4HJHA 4DULA 5FROA 4B24A 4RODB 2NOFA 1YTBA 4WXAA 4PY5A 1E42A 4ZTJA 4NZGA 1KEAA 4EAJA 1N3AA 4HSBA 2JOIA 4B22A 3OGDA 1WJWA 4BDYA 1NGNA 3HS8A 1TBAB 2OFIA 4E9HA 3ENOC 4ROEB 3L2QA 2HL8A 1VOLB 2JHNA 2YA3A 3I0WA 1JDYA 1U84A 3OYLA 3OYHA 2V75A 3CWTA 4B21A 4ZTFA 4OFHA 1YQLA 3L2VA 1TGHA 3OYKA 3UW2A 3OSEA 2HKPA 3OYIA 4UNFA 2R5XA 4EJZA 1V5SA 2W04A 1QN5A 2G30A 1EUVA 3OS0A 2LAEA 4ROCB 1T6AA 3ASMA 1UT4A 1QTPA 3G0QA 3OH6A 1P59A 1YTFA 4AIAA 2JG6A 1M3QA 3FSPA 4D7QA 2NOIA 3EAYA 1C9BB 4QG5A 2OOYA 2FUVA 3OCIA 5KL0A 2NLVA 3DPTA 4I8OA
chains in the Genus database with same CATH topology
1YQKA 3FHGA 1LWWA 4UOBA 1WEGA 3FHFA 4YPRA 1KG7A 3OH9A 4B24A 4EJYA 2NOFA 3CW7A 1N3CA 2OFKA 1RRSA 4YOQA 3D4VA 1KEAA 1MUNA 3KNTA 1KO9A 3IHOA 1N3AA 4HSBA 1DIZA 4DK9A 4B22A 4EA5A 1MPGA 3OGDA 4AI5A 1NGNA 1PU8A 4YPHA 4PIIA 1MUDA 4E9HA 2OFIA 1KG6A 2JHNA 2YG9A 1KG4A 5CHZA 3I0WA 5DPKA 4OFEA 1PVSA 3CWAA 4EA4A 4EW4A 1M3HA 4EVVA 1VRLA 1KQJA 3CWTA 4B21A 1HU0A 3N5NX 1EBMA 5KN9A 4OFHA 4EW0A 3F0ZA 1YQLA 4E9EA 3CWUA 1PU7A 3CWSA 1XG7A 5AN4A 2XHIA 4OFAA 3F10A 3N0UA 1YQMA 1ORNA 2NOHA 2I5WA 2NOBA 1KG5A 1YQRA 1KG2A 1FN7A 1LWVA 2YG8A 1XQOA 4UNFA 1N39A 4B23A 4EJZA 1WEFA 3IH7A 3CVSA 2NOEA 1P7MA 2JHJA 4AI4A 3KTUA 3CVTA 3G0QA 3OH6A 1P59A 1LWYA 4AIAA 1PU6A 1WEIA 1XQPA 2NOLA 2JG6A 4E9GA 2NOZA 4E9FA 1M3QA 1MUYA 3FSPA 3I0XA 1ORPA 5KN8A 2ABKA 1LMZA 1NKUA 2NOIA 1RRQA 3S6IA 1KG3A 2H56A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YQK A;  3FHG A;  1LWW A;  4UOB A;  1WEG A;  3FHF A;  4YPR A;  1KG7 A;  3OH9 A;  4B24 A;  4EJY A;  2NOF A;  3CW7 A;  1N3C A;  2OFK A;  1RRS A;  4YOQ A;  3D4V A;  1KEA A;  1MUN A;  3KNT A;  1KO9 A;  3IHO A;  1N3A A;  4HSB A;  1DIZ A;  4DK9 A;  4B22 A;  4EA5 A;  1MPG A;  3OGD A;  4AI5 A;  1NGN A;  1PU8 A;  4YPH A;  4PII A;  1MUD A;  4E9H A;  2OFI A;  1KG6 A;  2JHN A;  2YG9 A;  1KG4 A;  5CHZ A;  3I0W A;  5DPK A;  4OFE A;  1PVS A;  3CWA A;  4EA4 A;  4EW4 A;  1M3H A;  4EVV A;  1VRL A;  1KQJ A;  3CWT A;  4B21 A;  1HU0 A;  3N5N X;  1EBM A;  5KN9 A;  4OFH A;  4EW0 A;  3F0Z A;  1YQL A;  4E9E A;  3CWU A;  1PU7 A;  3CWS A;  1XG7 A;  5AN4 A;  2XHI A;  4OFA A;  3F10 A;  3N0U A;  1YQM A;  1ORN A;  2NOH A;  2I5W A;  2NOB A;  1KG5 A;  1YQR A;  1KG2 A;  1FN7 A;  1LWV A;  2YG8 A;  1XQO A;  4UNF A;  1N39 A;  4B23 A;  4EJZ A;  1WEF A;  3IH7 A;  3CVS A;  2NOE A;  1P7M A;  2JHJ A;  4AI4 A;  3KTU A;  3CVT A;  3G0Q A;  3OH6 A;  1P59 A;  1LWY A;  4AIA A;  1PU6 A;  1WEI A;  1XQP A;  2NOL A;  2JG6 A;  4E9G A;  2NOZ A;  4E9F A;  1M3Q A;  1MUY A;  3FSP A;  3I0X A;  1ORP A;  5KN8 A;  2ABK A;  1LMZ A;  1NKU A;  2NOI A;  1RRQ A;  3S6I A;  1KG3 A;  2H56 A; 
#chains in the Genus database with same CATH topology
 4UOB A;  3FHF A;  1KG7 A;  3EIK A;  3ENC A;  3CW7 A;  3ULX A;  1RRS A;  4YOQ A;  2FKF A;  4D7R A;  1J3M A;  1MUN A;  3KNT A;  3PDK A;  1QNE A;  5EPC A;  2IV9 A;  2H5A X;  1K35 A;  1DIZ A;  3L2R A;  4DK9 A;  3RSM A;  3OYC A;  2Y8Q A;  1MUD A;  3S3N A;  1TBP A;  1UL7 A;  3OS2 A;  2DKA A;  2YG9 A;  2DKC A;  1KG4 A;  1QN7 A;  1KY6 A;  3S3M A;  5DPK A;  1PVS A;  3N89 A;  4EA4 A;  4EW4 A;  2V8Q A;  4TPS A;  4IL8 A;  1W80 A;  2QRD A;  2PWW A;  2HZS A;  1PZD A;  1HU0 A;  3OYN A;  3L2U A;  5KN9 A;  4C7P A;  4EW0 A;  1JFI C;  4E7K A;  3CWU A;  1XG7 A;  2HZM A;  3OLP A;  1ORN A;  2NOH A;  1KG5 A;  1YQR A;  5FRM A;  1N39 A;  2JPS A;  5JMV D;  4Q11 A;  2V9J A;  2NVM A;  4BE2 A;  3C04 A;  2FKM X;  1MP9 A;  1R4X A;  3LCN A;  3HS9 A;  4IKF A;  3H1Z A;  2MZ8 A;  2V92 A;  2Z0F A;  2D0C A;  4WX8 A;  3SNS A;  1D3U A;  1XQP A;  4E7J A;  2NOZ A;  3I0X A;  1ORP A;  2ABK A;  1LMZ A;  1KYF A;  5BMP A;  1PCM X;  3VN5 A;  2D0B A;  3I3W A;  5IYD P;  2O3O A;  1RRQ A;  1RM1 A;  3FHG A;  1WEG A;  4YPR A;  1LXT A;  3NA5 A;  1PCJ X;  3OYF A;  5F9C A;  1VTL E;  3D4V A;  1KO9 A;  3IHO A;  1MPG A;  3OYM A;  1NVP A;  2HL9 A;  2F7L A;  4PII A;  1QN4 A;  3OC3 C;  1KYD A;  3BKQ X;  1P5D X;  3RPJ A;  4EAG A;  5FRN A;  1Q9U A;  3CWA A;  3TE5 A;  1M3H A;  4EVV A;  1KQJ A;  3N5N X;  1UT7 A;  4EAI A;  3CWS A;  1KFQ A;  5HSH A;  4EAL A;  1NGM A;  3OS1 A;  3VW4 A;  2Z8U A;  1QN6 A;  1KG2 A;  1FN7 A;  3OST A;  1LWV A;  4BDZ A;  2YG8 A;  4EAK A;  3T4N A;  1XQO A;  1PCZ A;  1WEF A;  5IYC P;  3CVS A;  2EHB D;  2JHJ A;  4AI4 A;  5BMN A;  1VTO A;  2W03 A;  2NWV A;  1LWY A;  1PU6 A;  3L2W A;  2NOL A;  2MJ7 A;  4E9F A;  4WZS D;  5KN8 A;  1KYU A;  1C4G A;  3S6I A;  3OYJ A;  1YQK A;  1LWW A;  4BE0 A;  4CFF A;  4MRQ A;  3OH9 A;  1B9K A;  3R2X C;  4EJY A;  1N3C A;  2OFK A;  1XSZ A;  1CDW A;  1AIS A;  1KY7 A;  3OSM A;  2YH5 A;  2DKD A;  5JN5 A;  3KRM A;  2D0A A;  1VKL A;  2JPI A;  1QN3 A;  4EA5 A;  3S3O A;  2H4L X;  4AI5 A;  2FGT A;  1PU8 A;  1WQA A;  4YPH A;  2QR1 A;  4BE1 A;  1KG6 A;  1NH2 A;  5CHZ A;  4E7H A;  1TUO A;  4OFE A;  3OYG A;  1VRL A;  1QNB A;  3TDH A;  2OOX A;  2VJ0 A;  1C47 A;  1QNC A;  1EBM A;  3PMG A;  2Y8L A;  3F0Z A;  4E9E A;  1PU7 A;  4B0A A;  4BAC A;  5AN4 A;  1M5Q 1;  2XHI A;  3D7Q A;  4OFA A;  2ZFD B;  3F10 A;  3N0U A;  1YQM A;  1QN9 A;  1QTS A;  2I5W A;  2NOB A;  3OYD A;  4B23 A;  2QRC A;  1KFI A;  3OYE A;  3IH7 A;  3OY9 A;  2NOE A;  2QRE A;  1P7M A;  5IYB P;  2IV8 A;  3NNQ A;  3KTU A;  2QLV A;  3CVT A;  1QNA A;  1WEI A;  1VOK A;  4E7I A;  3OYA A;  1P5G X;  4E9G A;  1MUY A;  1NKU A;  1K2Y X;  1KG3 A;  2H56 A;  3DPU A;  4E7L A;  4BJU A;  1QN8 A;  3OYB A;  4HJH A;  4DUL A;  5FRO A;  4B24 A;  4ROD B;  2NOF A;  1YTB A;  4WXA A;  4PY5 A;  1E42 A;  4ZTJ A;  4NZG A;  1KEA A;  4EAJ A;  1N3A A;  4HSB A;  2JOI A;  4B22 A;  3OGD A;  1WJW A;  4BDY A;  1NGN A;  3HS8 A;  1TBA B;  2OFI A;  4E9H A;  3ENO C;  4ROE B;  3L2Q A;  2HL8 A;  1VOL B;  2JHN A;  2YA3 A;  3I0W A;  1JDY A;  1U84 A;  3OYL A;  3OYH A;  2V75 A;  3CWT A;  4B21 A;  4ZTF A;  4OFH A;  1YQL A;  3L2V A;  1TGH A;  3OYK A;  3UW2 A;  3OSE A;  2HKP A;  3OYI A;  4UNF A;  2R5X A;  4EJZ A;  1V5S A;  2W04 A;  1QN5 A;  2G30 A;  1EUV A;  3OS0 A;  2LAE A;  4ROC B;  1T6A A;  3ASM A;  1UT4 A;  1QTP A;  3G0Q A;  3OH6 A;  1P59 A;  1YTF A;  4AIA A;  2JG6 A;  1M3Q A;  3FSP A;  4D7Q A;  2NOI A;  3EAY A;  1C9B B;  4QG5 A;  2OOY A;  2FUV A;  3OCI A;  5KL0 A;  2NLV A;  3DPT A;  4I8O A; 
#chains in the Genus database with same CATH homology
 1YQK A;  3FHG A;  1LWW A;  4UOB A;  1WEG A;  3FHF A;  4YPR A;  1KG7 A;  3OH9 A;  4B24 A;  4EJY A;  2NOF A;  3CW7 A;  1N3C A;  2OFK A;  1RRS A;  4YOQ A;  3D4V A;  1KEA A;  1MUN A;  3KNT A;  1KO9 A;  3IHO A;  1N3A A;  4HSB A;  1DIZ A;  4DK9 A;  4B22 A;  4EA5 A;  1MPG A;  3OGD A;  4AI5 A;  1NGN A;  1PU8 A;  4YPH A;  4PII A;  1MUD A;  4E9H A;  2OFI A;  1KG6 A;  2JHN A;  2YG9 A;  1KG4 A;  5CHZ A;  3I0W A;  5DPK A;  4OFE A;  1PVS A;  3CWA A;  4EA4 A;  4EW4 A;  1M3H A;  4EVV A;  1VRL A;  1KQJ A;  3CWT A;  4B21 A;  1HU0 A;  3N5N X;  1EBM A;  5KN9 A;  4OFH A;  4EW0 A;  3F0Z A;  1YQL A;  4E9E A;  3CWU A;  1PU7 A;  3CWS A;  1XG7 A;  5AN4 A;  2XHI A;  4OFA A;  3F10 A;  3N0U A;  1YQM A;  1ORN A;  2NOH A;  2I5W A;  2NOB A;  1KG5 A;  1YQR A;  1KG2 A;  1FN7 A;  1LWV A;  2YG8 A;  1XQO A;  4UNF A;  1N39 A;  4B23 A;  4EJZ A;  1WEF A;  3IH7 A;  3CVS A;  2NOE A;  1P7M A;  2JHJ A;  4AI4 A;  3KTU A;  3CVT A;  3G0Q A;  3OH6 A;  1P59 A;  1LWY A;  4AIA A;  1PU6 A;  1WEI A;  1XQP A;  2NOL A;  2JG6 A;  4E9G A;  2NOZ A;  4E9F A;  1M3Q A;  1MUY A;  3FSP A;  3I0X A;  1ORP A;  5KN8 A;  2ABK A;  1LMZ A;  1NKU A;  2NOI A;  1RRQ A;  3S6I A;  1KG3 A;  2H56 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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