1PVSA

3-methyladenine glcosylase ii(alka) hypoxanthine complex
Total Genus 89
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
282
structure length
282
Chain Sequence
MYTLNWQPPYDWSWMLGFLAARAVSSVETVADSYYARSLAVGEYRGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGRLGAARPGLRLPGCVDAFEQGVRAILGQLVSVAMAAKLTARVAQLYGERLDDFPEYICFPTPQRLAAADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRWTANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEGWQPDEA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title 3-methyladenine-DNA glycosylase II: the crystal structure of an AlkA-hypoxanthine complex suggests the possibility of product inhibition.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords DNA-3-methyladenine glycosylase II
total genus 89
structure length 282
sequence length 282
chains with identical sequence B
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 2003-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF06029 AlkA_N AlkA N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1pvsA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1pvsA03
3.30.310.20 Alpha Beta 2-Layer Sandwich TATA-Binding Protein DNA-3-methyladenine glycosylase AlkA, N-terminal domain 1pvsA01
3CW7A 4E9HA 4EW0A 2JHJA 4E9FA 3F0ZA 4EA5A 4OFEA 4EW4A 3IH7A 4EVVA 1KEAA 1KG6A 1P59A 2OFIA 1MUDA 1EBMA 1WEFA 3KNTA 1N3AA 4DK9A 2NOHA 1WEIA 1LWWA 1PU7A 3CWSA 3F10A 1N39A 1KG3A 4EJZA 4B24A 5KN8A 5CHZA 3G0QA 1KG5A 2NOFA 4B21A 3I0XA 1WEGA 1MPGA 1NKUA 2H56A 1FN7A 3N0UA 4E9GA 2JG6A 1ORNA 1XQPA 3OH6A 2NOZA 4EA4A 4AIAA 3N5NX 4OFHA 1PU6A 4YPRA 3FSPA 3FHGA 2YG9A 1P7MA 3OH9A 1PVSA 4OFAA 1XQOA 1LWYA 1LWVA 1DIZA 1M3QA 2NOIA 4HSBA 3KTUA 1PU8A 2ABKA 3FHFA 3CWUA 4B22A 1M3HA 1VRLA 2NOLA 1NGNA 1YQLA 4B23A 1RRSA 4AI5A 2NOBA 1YQMA 4UOBA 3IHOA 3S6IA 1YQRA 1KG7A 1HU0A 1KG2A 1KG4A 5KN9A 2JHNA 2I5WA 4YOQA 5DPKA 3I0WA 4YPHA 4EJYA 4PIIA 1KO9A 1ORPA 4AI4A 1MUNA 3D4VA 2NOEA 2XHIA 3CWAA 1YQKA 1LMZA 3CVSA 5AN4A 1KQJA 1XG7A 3OGDA 3CWTA 1MUYA 3CVTA 1N3CA 1RRQA 4E9EA 2YG8A 4UNFA 2OFKA
chains in the Genus database with same CATH superfamily
4E9HA 5JMVD 4EW0A 2FKMX 3EAYA 2EHBD 1VOKA 4BE0A 1VTLE 2D0CA 2FKFA 4BJUA 3IH7A 1P59A 4NZGA 3CWSA 1KG3A 1QNEA 5FRMA 2NLVA 3G0QA 1KG5A 2NOFA 1WJWA 4B21A 4BDYA 2DKAA 3I0XA 3PMGA 1FN7A 2HL9A 2HZSA 3EIKA 4WZSD 1EUVA 2R5XA 1ORNA 3OH6A 2NOZA 4EA4A 3N5NX 3OYAA 1PU6A 4EAJA 3N89A 1QN8A 1QNAA 3OH9A 2O3OA 5F9CA 2JPSA 1NVPA 1QNCA 1PZDA 1E42A 1AISA 1M3QA 1TGHA 4D7QA 3UW2A 3L2VA 3FHFA 4B22A 3I3WA 4HJHA 4UOBA 3S6IA 3OYIA 1YQRA 4Q11A 2I5WA 4ROCB 1UT7A 1ORPA 1UT4A 3D4VA 1VTOA 5IYDP 5AN4A 3OYEA 2DKDA 4ZTFA 5HSHA 3CWTA 3CVTA 2JOIA 4BE2A 4E7KA 2Z0FA 2MJ7A 3CW7A 2HKPA 2Y8QA 4E9FA 2W03A 1CDWA 3NA5A 4I8OA 5JN5A 4BACA 1YTFA 3TDHA 1KG6A 1EBMA 4DK9A 3L2QA 1K35A 1LWWA 3OY9A 4E7HA 4CFFA 1N39A 1T6AA 5KN8A 4TPSA 3SNSA 2HL8A 1MPGA 1TUOA 4IL8A 1C9BB 2PWWA 1MP9A 3FHGA 3DPTA 3ENCA 1QTPA 3RSMA 4EAKA 1P7MA 3BKQX 2OOXA 2HZMA 1LWYA 1DIZA 4HSBA 4WXAA 1JFIC 4EALA 1KYFA 4E7IA 3CWUA 3NNQA 2LAEA 1VRLA 2JPIA 1RRSA 2NOBA 3OYLA 2IV8A 1P5GX 3VN5A 3RPJA 5IYCP 1J3MA 4YOQA 3R2XC 2F7LA 4EJYA 4PIIA 1KO9A 5EPCA 1QTSA 1MUNA 3C04A 3PDKA 3CVSA 2VJ0A 3KRMA 2IV9A 4ZTJA 4MRQA 1TBAB 1XG7A 4IKFA 1VKLA 1RRQA 4E7LA 4PY5A 2JHJA 3HS8A 5KL0A 1W80A 4OFEA 3T4NA 4EW4A 1P5DX 4EVVA 3OYBA 1KYDA 2OFIA 1MUDA 1WEFA 1N3AA 2QREA 2QRDA 2NOHA 3OS0A 1WEIA 1QNBA 3OYDA 3H1ZA 2QR1A 3F10A 2H4LX 4B24A 4B0AA 2Y8LA 5CHZA 3LCNA 2QRCA 4ROEB 2H5AX 3S3MA 3OSTA 4AIAA 3VW4A 1WQAA 4OFHA 3OLPA 4YPRA 3FSPA 2YG9A 4C7PA 2FUVA 1RM1A 2W04A 1UL7A 1XQOA 3DPUA 1LWVA 1PU8A 1M5Q1 4UNFA 3L2RA 2ABKA 3OYMA 2NOLA 4AI5A 2G30A 3OYNA 1PCZA 3IHOA 2ZFDB 4WX8A 1KG7A 1HU0A 1KG2A 1KG4A 5KN9A 4E7JA 3OYJA 5FRNA 4RODB 1K2YX 1TBPA 1QN6A 1U84A 1VOLB 3S3NA 3TE5A 5FROA 1JDYA 1R4XA 1QN7A 2NOEA 1QN9A 3ASMA 1KQJA 2MZ8A 2YH5A 4DULA 2OFKA 3OSEA 2D0AA 3F0ZA 4EA5A 1YTBA 3OSMA 4QG5A 1KEAA 3KNTA 3L2UA 2FGTA 4EAIA 1PU7A 1KFQA 3OS1A 4EJZA 3OCIA 1PCJX 3OYFA 3OYGA 1XSZA 1KYUA 5IYBP 5BMNA 1NGMA 1WEGA 1NKUA 2H56A 3N0UA 3OYKA 4D7RA 4E9GA 2JG6A 1PCMX 1XQPA 3S3OA 5BMPA 2V9JA 2DKCA 1B9KA 1QN4A 3ULXA 1D3UA 1Q9UA 1PVSA 2OOYA 4OFAA 3OS2A 4BDZA 2NOIA 3KTUA 3D7QA 1C47A 3OYHA 1M3HA 2YA3A 2QLVA 1LXTA 1NGNA 1YQLA 4B23A 1C4GA 1YQMA 1QN3A 3HS9A 1NH2A 2JHNA 1V5SA 3OYCA 5DPKA 3I0WA 4YPHA 4EAGA 3L2WA 2NWVA 4AI4A 2V8QA 1QN5A 2XHIA 2D0BA 3CWAA 4BE1A 1YQKA 3OC3C 1LMZA 1KY7A 3ENOC 1KY6A 1KFIA 3OGDA 2V75A 1MUYA 1N3CA 2V92A 2Z8UA 4E9EA 2YG8A 2NVMA
chains in the Genus database with same CATH topology
3CW7A 4E9HA 4EW0A 2JHJA 4E9FA 3F0ZA 4EA5A 4OFEA 4EW4A 3IH7A 4EVVA 1KEAA 1KG6A 1P59A 2OFIA 1MUDA 1EBMA 1WEFA 3KNTA 1N3AA 4DK9A 2NOHA 1WEIA 1LWWA 1PU7A 3CWSA 3F10A 1N39A 1KG3A 4EJZA 4B24A 5KN8A 5CHZA 3G0QA 1KG5A 2NOFA 4B21A 3I0XA 1WEGA 1MPGA 1NKUA 2H56A 1FN7A 3N0UA 4E9GA 2JG6A 1ORNA 1XQPA 3OH6A 2NOZA 4EA4A 4AIAA 3N5NX 4OFHA 1PU6A 4YPRA 3FSPA 3FHGA 2YG9A 1P7MA 3OH9A 1PVSA 4OFAA 1XQOA 1LWYA 1LWVA 1DIZA 1M3QA 2NOIA 4HSBA 3KTUA 1PU8A 2ABKA 3FHFA 3CWUA 4B22A 1M3HA 1VRLA 2NOLA 1NGNA 1YQLA 4B23A 1RRSA 4AI5A 2NOBA 1YQMA 4UOBA 3IHOA 3S6IA 1YQRA 1KG7A 1HU0A 1KG2A 1KG4A 5KN9A 2JHNA 2I5WA 4YOQA 5DPKA 3I0WA 4YPHA 4EJYA 4PIIA 1KO9A 1ORPA 4AI4A 1MUNA 3D4VA 2NOEA 2XHIA 3CWAA 1YQKA 1LMZA 3CVSA 5AN4A 1KQJA 1XG7A 3OGDA 3CWTA 1MUYA 3CVTA 1N3CA 1RRQA 4E9EA 2YG8A 4UNFA 2OFKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CW7 A;  4E9H A;  4EW0 A;  2JHJ A;  4E9F A;  3F0Z A;  4EA5 A;  4OFE A;  4EW4 A;  3IH7 A;  4EVV A;  1KEA A;  1KG6 A;  1P59 A;  2OFI A;  1MUD A;  1EBM A;  1WEF A;  3KNT A;  1N3A A;  4DK9 A;  2NOH A;  1WEI A;  1LWW A;  1PU7 A;  3CWS A;  3F10 A;  1N39 A;  1KG3 A;  4EJZ A;  4B24 A;  5KN8 A;  5CHZ A;  3G0Q A;  1KG5 A;  2NOF A;  4B21 A;  3I0X A;  1WEG A;  1MPG A;  1NKU A;  2H56 A;  1FN7 A;  3N0U A;  4E9G A;  2JG6 A;  1ORN A;  1XQP A;  3OH6 A;  2NOZ A;  4EA4 A;  4AIA A;  3N5N X;  4OFH A;  1PU6 A;  4YPR A;  3FSP A;  3FHG A;  2YG9 A;  1P7M A;  3OH9 A;  1PVS A;  4OFA A;  1XQO A;  1LWY A;  1LWV A;  1DIZ A;  1M3Q A;  2NOI A;  4HSB A;  3KTU A;  1PU8 A;  2ABK A;  3FHF A;  3CWU A;  4B22 A;  1M3H A;  1VRL A;  2NOL A;  1NGN A;  1YQL A;  4B23 A;  1RRS A;  4AI5 A;  2NOB A;  1YQM A;  4UOB A;  3IHO A;  3S6I A;  1YQR A;  1KG7 A;  1HU0 A;  1KG2 A;  1KG4 A;  5KN9 A;  2JHN A;  2I5W A;  4YOQ A;  5DPK A;  3I0W A;  4YPH A;  4EJY A;  4PII A;  1KO9 A;  1ORP A;  4AI4 A;  1MUN A;  3D4V A;  2NOE A;  2XHI A;  3CWA A;  1YQK A;  1LMZ A;  3CVS A;  5AN4 A;  1KQJ A;  1XG7 A;  3OGD A;  3CWT A;  1MUY A;  3CVT A;  1N3C A;  1RRQ A;  4E9E A;  2YG8 A;  4UNF A;  2OFK A; 
#chains in the Genus database with same CATH topology
 4E9H A;  5JMV D;  4EW0 A;  2FKM X;  3EAY A;  2EHB D;  1VOK A;  4BE0 A;  1VTL E;  2D0C A;  2FKF A;  4BJU A;  3IH7 A;  1P59 A;  4NZG A;  3CWS A;  1KG3 A;  1QNE A;  5FRM A;  2NLV A;  3G0Q A;  1KG5 A;  2NOF A;  1WJW A;  4B21 A;  4BDY A;  2DKA A;  3I0X A;  3PMG A;  1FN7 A;  2HL9 A;  2HZS A;  3EIK A;  4WZS D;  1EUV A;  2R5X A;  1ORN A;  3OH6 A;  2NOZ A;  4EA4 A;  3N5N X;  3OYA A;  1PU6 A;  4EAJ A;  3N89 A;  1QN8 A;  1QNA A;  3OH9 A;  2O3O A;  5F9C A;  2JPS A;  1NVP A;  1QNC A;  1PZD A;  1E42 A;  1AIS A;  1M3Q A;  1TGH A;  4D7Q A;  3UW2 A;  3L2V A;  3FHF A;  4B22 A;  3I3W A;  4HJH A;  4UOB A;  3S6I A;  3OYI A;  1YQR A;  4Q11 A;  2I5W A;  4ROC B;  1UT7 A;  1ORP A;  1UT4 A;  3D4V A;  1VTO A;  5IYD P;  5AN4 A;  3OYE A;  2DKD A;  4ZTF A;  5HSH A;  3CWT A;  3CVT A;  2JOI A;  4BE2 A;  4E7K A;  2Z0F A;  2MJ7 A;  3CW7 A;  2HKP A;  2Y8Q A;  4E9F A;  2W03 A;  1CDW A;  3NA5 A;  4I8O A;  5JN5 A;  4BAC A;  1YTF A;  3TDH A;  1KG6 A;  1EBM A;  4DK9 A;  3L2Q A;  1K35 A;  1LWW A;  3OY9 A;  4E7H A;  4CFF A;  1N39 A;  1T6A A;  5KN8 A;  4TPS A;  3SNS A;  2HL8 A;  1MPG A;  1TUO A;  4IL8 A;  1C9B B;  2PWW A;  1MP9 A;  3FHG A;  3DPT A;  3ENC A;  1QTP A;  3RSM A;  4EAK A;  1P7M A;  3BKQ X;  2OOX A;  2HZM A;  1LWY A;  1DIZ A;  4HSB A;  4WXA A;  1JFI C;  4EAL A;  1KYF A;  4E7I A;  3CWU A;  3NNQ A;  2LAE A;  1VRL A;  2JPI A;  1RRS A;  2NOB A;  3OYL A;  2IV8 A;  1P5G X;  3VN5 A;  3RPJ A;  5IYC P;  1J3M A;  4YOQ A;  3R2X C;  2F7L A;  4EJY A;  4PII A;  1KO9 A;  5EPC A;  1QTS A;  1MUN A;  3C04 A;  3PDK A;  3CVS A;  2VJ0 A;  3KRM A;  2IV9 A;  4ZTJ A;  4MRQ A;  1TBA B;  1XG7 A;  4IKF A;  1VKL A;  1RRQ A;  4E7L A;  4PY5 A;  2JHJ A;  3HS8 A;  5KL0 A;  1W80 A;  4OFE A;  3T4N A;  4EW4 A;  1P5D X;  4EVV A;  3OYB A;  1KYD A;  2OFI A;  1MUD A;  1WEF A;  1N3A A;  2QRE A;  2QRD A;  2NOH A;  3OS0 A;  1WEI A;  1QNB A;  3OYD A;  3H1Z A;  2QR1 A;  3F10 A;  2H4L X;  4B24 A;  4B0A A;  2Y8L A;  5CHZ A;  3LCN A;  2QRC A;  4ROE B;  2H5A X;  3S3M A;  3OST A;  4AIA A;  3VW4 A;  1WQA A;  4OFH A;  3OLP A;  4YPR A;  3FSP A;  2YG9 A;  4C7P A;  2FUV A;  1RM1 A;  2W04 A;  1UL7 A;  1XQO A;  3DPU A;  1LWV A;  1PU8 A;  1M5Q 1;  4UNF A;  3L2R A;  2ABK A;  3OYM A;  2NOL A;  4AI5 A;  2G30 A;  3OYN A;  1PCZ A;  3IHO A;  2ZFD B;  4WX8 A;  1KG7 A;  1HU0 A;  1KG2 A;  1KG4 A;  5KN9 A;  4E7J A;  3OYJ A;  5FRN A;  4ROD B;  1K2Y X;  1TBP A;  1QN6 A;  1U84 A;  1VOL B;  3S3N A;  3TE5 A;  5FRO A;  1JDY A;  1R4X A;  1QN7 A;  2NOE A;  1QN9 A;  3ASM A;  1KQJ A;  2MZ8 A;  2YH5 A;  4DUL A;  2OFK A;  3OSE A;  2D0A A;  3F0Z A;  4EA5 A;  1YTB A;  3OSM A;  4QG5 A;  1KEA A;  3KNT A;  3L2U A;  2FGT A;  4EAI A;  1PU7 A;  1KFQ A;  3OS1 A;  4EJZ A;  3OCI A;  1PCJ X;  3OYF A;  3OYG A;  1XSZ A;  1KYU A;  5IYB P;  5BMN A;  1NGM A;  1WEG A;  1NKU A;  2H56 A;  3N0U A;  3OYK A;  4D7R A;  4E9G A;  2JG6 A;  1PCM X;  1XQP A;  3S3O A;  5BMP A;  2V9J A;  2DKC A;  1B9K A;  1QN4 A;  3ULX A;  1D3U A;  1Q9U A;  1PVS A;  2OOY A;  4OFA A;  3OS2 A;  4BDZ A;  2NOI A;  3KTU A;  3D7Q A;  1C47 A;  3OYH A;  1M3H A;  2YA3 A;  2QLV A;  1LXT A;  1NGN A;  1YQL A;  4B23 A;  1C4G A;  1YQM A;  1QN3 A;  3HS9 A;  1NH2 A;  2JHN A;  1V5S A;  3OYC A;  5DPK A;  3I0W A;  4YPH A;  4EAG A;  3L2W A;  2NWV A;  4AI4 A;  2V8Q A;  1QN5 A;  2XHI A;  2D0B A;  3CWA A;  4BE1 A;  1YQK A;  3OC3 C;  1LMZ A;  1KY7 A;  3ENO C;  1KY6 A;  1KFI A;  3OGD A;  2V75 A;  1MUY A;  1N3C A;  2V92 A;  2Z8U A;  4E9E A;  2YG8 A;  2NVM A; 
#chains in the Genus database with same CATH homology
 3CW7 A;  4E9H A;  4EW0 A;  2JHJ A;  4E9F A;  3F0Z A;  4EA5 A;  4OFE A;  4EW4 A;  3IH7 A;  4EVV A;  1KEA A;  1KG6 A;  1P59 A;  2OFI A;  1MUD A;  1EBM A;  1WEF A;  3KNT A;  1N3A A;  4DK9 A;  2NOH A;  1WEI A;  1LWW A;  1PU7 A;  3CWS A;  3F10 A;  1N39 A;  1KG3 A;  4EJZ A;  4B24 A;  5KN8 A;  5CHZ A;  3G0Q A;  1KG5 A;  2NOF A;  4B21 A;  3I0X A;  1WEG A;  1MPG A;  1NKU A;  2H56 A;  1FN7 A;  3N0U A;  4E9G A;  2JG6 A;  1ORN A;  1XQP A;  3OH6 A;  2NOZ A;  4EA4 A;  4AIA A;  3N5N X;  4OFH A;  1PU6 A;  4YPR A;  3FSP A;  3FHG A;  2YG9 A;  1P7M A;  3OH9 A;  1PVS A;  4OFA A;  1XQO A;  1LWY A;  1LWV A;  1DIZ A;  1M3Q A;  2NOI A;  4HSB A;  3KTU A;  1PU8 A;  2ABK A;  3FHF A;  3CWU A;  4B22 A;  1M3H A;  1VRL A;  2NOL A;  1NGN A;  1YQL A;  4B23 A;  1RRS A;  4AI5 A;  2NOB A;  1YQM A;  4UOB A;  3IHO A;  3S6I A;  1YQR A;  1KG7 A;  1HU0 A;  1KG2 A;  1KG4 A;  5KN9 A;  2JHN A;  2I5W A;  4YOQ A;  5DPK A;  3I0W A;  4YPH A;  4EJY A;  4PII A;  1KO9 A;  1ORP A;  4AI4 A;  1MUN A;  3D4V A;  2NOE A;  2XHI A;  3CWA A;  1YQK A;  1LMZ A;  3CVS A;  5AN4 A;  1KQJ A;  1XG7 A;  3OGD A;  3CWT A;  1MUY A;  3CVT A;  1N3C A;  1RRQ A;  4E9E A;  2YG8 A;  4UNF A;  2OFK A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...