1PVSA

3-methyladenine glcosylase ii(alka) hypoxanthine complex
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
282
structure length
282
Chain Sequence
MYTLNWQPPYDWSWMLGFLAARAVSSVETVADSYYARSLAVGEYRGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGRLGAARPGLRLPGCVDAFEQGVRAILGQLVSVAMAAKLTARVAQLYGERLDDFPEYICFPTPQRLAAADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRWTANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEGWQPDEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 3-methyladenine-DNA glycosylase II: the crystal structure of an AlkA-hypoxanthine complex suggests the possibility of product inhibition.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords DNA-3-methyladenine glycosylase II
total genus 89
structure length 282
sequence length 282
chains with identical sequence B
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 2003-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF06029 AlkA_N AlkA N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 1pvsA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 1pvsA03
3.30.310.20 Alpha Beta 2-Layer Sandwich TATA-Binding Protein DNA-3-methyladenine glycosylase AlkA, N-terminal domain 1pvsA01
2OFKA 3IHOA 3OGDA 1WEIA 2NOBA 1N3AA 4EVVA 3OH6A 1RRQA 4E9EA 1LWWA 2NOIA 4UOBA 2ABKA 1KG4A 2XHIA 1YQLA 1KEAA 1XQOA 4EW4A 3F0ZA 1NGNA 3CWUA 1N39A 1P7MA 4E9GA 1KG6A 2JHNA 3G0QA 1VRLA 1WEGA 4EA5A 1YQKA 1KO9A 4OFEA 1M3HA 4EA4A 4AI4A 4E9FA 4B22A 4OFHA 1YQRA 1HU0A 2NOLA 4YPHA 2YG9A 1YQMA 5KN9A 3I0WA 1XG7A 3N5NX 4PIIA 2H56A 4EJYA 4AIAA 3I0XA 4HSBA 1LWVA 1FN7A 1PU7A 1XQPA 4DK9A 1LWYA 3CWSA 3FHFA 1PVSA 3KTUA 2NOEA 3FSPA 2NOFA 1M3QA 2JHJA 4EJZA 3D4VA 5CHZA 4B21A 3OH9A 4OFAA 4UNFA 1MUDA 3IH7A 2OFIA 5DPKA 3CW7A 1MPGA 4AI5A 5KN8A 1PU6A 3KNTA 4B24A 1KG2A 1RRSA 1DIZA 1MUNA 3CWAA 1PU8A 1N3CA 2I5WA 1ORNA 3N0UA 3S6IA 2JG6A 3CVSA 1NKUA 1KG5A 3CVTA 3CWTA 3F10A 1EBMA 4YOQA 1KG7A 2NOZA 2NOHA 1WEFA 4B23A 3FHGA 1KQJA 4E9HA 1P59A 1LMZA 1KG3A 5AN4A 4YPRA 1ORPA 4EW0A 1MUYA 2YG8A
chains in the Genus database with same CATH superfamily
1QN6A 2NOBA 1N3AA 2ZFDB 4E9EA 2XHIA 2JOIA 3OSMA 3ULXA 2HKPA 3L2WA 1YQLA 4MRQA 3OSTA 4EW4A 2LAEA 5IYDP 1MP9A 2IV8A 1P7MA 2JPSA 1UT4A 1KG6A 2O3OA 2F7LA 3OS0A 1NGMA 4B0AA 3OYMA 1K2YX 1WEGA 1YQKA 1B9KA 4OFEA 2H5AX 2QR1A 1T6AA 4QG5A 2YG9A 5FROA 3OY9A 3N5NX 3L2QA 5HSHA 3OYIA 3VN5A 4D7RA 1KFIA 3CWSA 1AISA 2G30A 1PCJX 1LXTA 1C47A 2NOFA 2QLVA 2W04A 1D3UA 4I8OA 5CHZA 4OFAA 1PCZA 1KYFA 3IH7A 2PWWA 3S3OA 3OYHA 1KG2A 4BE0A 3KNTA 2Y8QA 4C7PA 5F9CA 1CDWA 3KRMA 3CWTA 3F10A 1KG7A 2NOHA 1WEFA 1Q9UA 4E9HA 3OYFA 1YTBA 1LMZA 2OOXA 1VOLB 4EA4A 4YPRA 1ORPA 4EW0A 1PCMX 1MUYA 2YG8A 3VW4A 3IHOA 1TUOA 3OH6A 2OOYA 1RRQA 1LWWA 1QNAA 2Z0FA 1QN4A 2QREA 1R4XA 1KEAA 2QRDA 3F0ZA 3L2VA 3DPUA 1WQAA 4E9GA 1UL7A 5KL0A 1NH2A 1QTSA 3NNQA 1VRLA 1P5GX 4E7LA 2DKCA 4ROEB 4BDZA 2YA3A 4B22A 2H4LX 2HZMA 4BE2A 1HU0A 4HJHA 3EIKA 4E7KA 2D0CA 1QN5A 4AIAA 4HSBA 3OYJA 2DKAA 1FN7A 1KY7A 4PY5A 2R5XA 4WZSD 3FHFA 3OYBA 2JHJA 3OYGA 3DPTA 1KFQA 2MZ8A 3OLPA 4B21A 2FKFA 3CW7A 1MPGA 4AI5A 4NZGA 1PU6A 5JN5A 1PU8A 3C04A 1N3CA 2I5WA 1ORNA 1QN3A 4BE1A 2JG6A 1KG5A 3T4NA 1KY6A 4YOQA 3OYLA 1QN8A 4EAJA 4ZTJA 1UT7A 1J3MA 4EAKA 3OYCA 2OFKA 2JPIA 1WEIA 2NLVA 1W80A 1WJWA 3I3WA 4EVVA 1JFIC 1PZDA 4UOBA 3BKQX 2NVMA 1XQOA 2EHBD 3R2XC 2HL8A 1YTFA 1N39A 3L2UA 1XSZA 3EAYA 1TBAB 3ASMA 3S3MA 2JHNA 4EA5A 1NVPA 2W03A 2HZSA 1M3HA 1YQRA 3RSMA 3OS1A 3D7QA 4E7IA 4YPHA 1YQMA 5BMPA 3I0WA 2VJ0A 3ENOC 2D0BA 4PIIA 3OYAA 4EJYA 3I0XA 4IL8A 1JDYA 4DK9A 1LWYA 4E7HA 2MJ7A 1PVSA 3KTUA 2NOEA 3FSPA 1M3QA 4BACA 2V92A 3RPJA 5FRMA 3OH9A 4UNFA 2OFIA 5DPKA 2DKDA 4RODB 4B24A 1DIZA 3CWAA 2FGTA 1QNBA 1E42A 3N0UA 1K35A 4DULA 2V75A 3CVSA 1NKUA 1EBMA 3OS2A 1TBPA 2HL9A 1KQJA 2V8QA 4TPSA 5FRNA 1P5DX 1QN7A 1KG3A 2IV9A 4BDYA 5JMVD 3OGDA 4CFFA 2QRCA 5IYBP 2NOIA 2ABKA 4E7JA 1KG4A 3N89A 3PMGA 2NWVA 3NA5A 2Z8UA 1EUVA 1NGNA 3CWUA 3UW2A 3PDKA 2D0AA 1VKLA 2Y8LA 4WXAA 4IKFA 1VTOA 3G0QA 2YH5A 3OCIA 4ROCB 1KO9A 2V9JA 3HS8A 1VTLE 4AI4A 4E9FA 3SNSA 1M5Q1 3H1ZA 4OFHA 3TE5A 3ENCA 2NOLA 1RM1A 1QTPA 5EPCA 4Q11A 2FKMX 1V5SA 1C4GA 5KN9A 3L2RA 1XG7A 4BJUA 1KYUA 5BMNA 3OYKA 4D7QA 2H56A 1LWVA 4EAGA 1QN9A 1PU7A 1XQPA 3OSEA 4EAIA 3HS9A 1U84A 2FUVA 1TGHA 3OYEA 1VOKA 4EJZA 3D4VA 4EALA 4WX8A 1MUDA 5KN8A 4ZTFA 3OYNA 1RRSA 3OYDA 1MUNA 3LCNA 3S6IA 3CVTA 2NOZA 4B23A 3FHGA 1C9BB 1KYDA 5IYCP 3TDHA 1P59A 1QNEA 3OC3C 5AN4A 3S3NA 1QNCA
chains in the Genus database with same CATH topology
2OFKA 3IHOA 3OGDA 1WEIA 2NOBA 1N3AA 4EVVA 3OH6A 1RRQA 4E9EA 1LWWA 2NOIA 4UOBA 2ABKA 1KG4A 2XHIA 1YQLA 1KEAA 1XQOA 4EW4A 3F0ZA 1NGNA 3CWUA 1N39A 1P7MA 4E9GA 1KG6A 2JHNA 3G0QA 1VRLA 1WEGA 4EA5A 1YQKA 1KO9A 4OFEA 1M3HA 4EA4A 4AI4A 4E9FA 4B22A 4OFHA 1YQRA 1HU0A 2NOLA 4YPHA 2YG9A 1YQMA 5KN9A 3I0WA 1XG7A 3N5NX 4PIIA 2H56A 4EJYA 4AIAA 3I0XA 4HSBA 1LWVA 1FN7A 1PU7A 1XQPA 4DK9A 1LWYA 3CWSA 3FHFA 1PVSA 3KTUA 2NOEA 3FSPA 2NOFA 1M3QA 2JHJA 4EJZA 3D4VA 5CHZA 4B21A 3OH9A 4OFAA 4UNFA 1MUDA 3IH7A 2OFIA 5DPKA 3CW7A 1MPGA 4AI5A 5KN8A 1PU6A 3KNTA 4B24A 1KG2A 1RRSA 1DIZA 1MUNA 3CWAA 1PU8A 1N3CA 2I5WA 1ORNA 3N0UA 3S6IA 2JG6A 3CVSA 1NKUA 1KG5A 3CVTA 3CWTA 3F10A 1EBMA 4YOQA 1KG7A 2NOZA 2NOHA 1WEFA 4B23A 3FHGA 1KQJA 4E9HA 1P59A 1LMZA 1KG3A 5AN4A 4YPRA 1ORPA 4EW0A 1MUYA 2YG8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OFK A;  3IHO A;  3OGD A;  1WEI A;  2NOB A;  1N3A A;  4EVV A;  3OH6 A;  1RRQ A;  4E9E A;  1LWW A;  2NOI A;  4UOB A;  2ABK A;  1KG4 A;  2XHI A;  1YQL A;  1KEA A;  1XQO A;  4EW4 A;  3F0Z A;  1NGN A;  3CWU A;  1N39 A;  1P7M A;  4E9G A;  1KG6 A;  2JHN A;  3G0Q A;  1VRL A;  1WEG A;  4EA5 A;  1YQK A;  1KO9 A;  4OFE A;  1M3H A;  4EA4 A;  4AI4 A;  4E9F A;  4B22 A;  4OFH A;  1YQR A;  1HU0 A;  2NOL A;  4YPH A;  2YG9 A;  1YQM A;  5KN9 A;  3I0W A;  1XG7 A;  3N5N X;  4PII A;  2H56 A;  4EJY A;  4AIA A;  3I0X A;  4HSB A;  1LWV A;  1FN7 A;  1PU7 A;  1XQP A;  4DK9 A;  1LWY A;  3CWS A;  3FHF A;  1PVS A;  3KTU A;  2NOE A;  3FSP A;  2NOF A;  1M3Q A;  2JHJ A;  4EJZ A;  3D4V A;  5CHZ A;  4B21 A;  3OH9 A;  4OFA A;  4UNF A;  1MUD A;  3IH7 A;  2OFI A;  5DPK A;  3CW7 A;  1MPG A;  4AI5 A;  5KN8 A;  1PU6 A;  3KNT A;  4B24 A;  1KG2 A;  1RRS A;  1DIZ A;  1MUN A;  3CWA A;  1PU8 A;  1N3C A;  2I5W A;  1ORN A;  3N0U A;  3S6I A;  2JG6 A;  3CVS A;  1NKU A;  1KG5 A;  3CVT A;  3CWT A;  3F10 A;  1EBM A;  4YOQ A;  1KG7 A;  2NOZ A;  2NOH A;  1WEF A;  4B23 A;  3FHG A;  1KQJ A;  4E9H A;  1P59 A;  1LMZ A;  1KG3 A;  5AN4 A;  4YPR A;  1ORP A;  4EW0 A;  1MUY A;  2YG8 A; 
#chains in the Genus database with same CATH topology
 1QN6 A;  2NOB A;  1N3A A;  2ZFD B;  4E9E A;  2XHI A;  2JOI A;  3OSM A;  3ULX A;  2HKP A;  3L2W A;  1YQL A;  4MRQ A;  3OST A;  4EW4 A;  2LAE A;  5IYD P;  1MP9 A;  2IV8 A;  1P7M A;  2JPS A;  1UT4 A;  1KG6 A;  2O3O A;  2F7L A;  3OS0 A;  1NGM A;  4B0A A;  3OYM A;  1K2Y X;  1WEG A;  1YQK A;  1B9K A;  4OFE A;  2H5A X;  2QR1 A;  1T6A A;  4QG5 A;  2YG9 A;  5FRO A;  3OY9 A;  3N5N X;  3L2Q A;  5HSH A;  3OYI A;  3VN5 A;  4D7R A;  1KFI A;  3CWS A;  1AIS A;  2G30 A;  1PCJ X;  1LXT A;  1C47 A;  2NOF A;  2QLV A;  2W04 A;  1D3U A;  4I8O A;  5CHZ A;  4OFA A;  1PCZ A;  1KYF A;  3IH7 A;  2PWW A;  3S3O A;  3OYH A;  1KG2 A;  4BE0 A;  3KNT A;  2Y8Q A;  4C7P A;  5F9C A;  1CDW A;  3KRM A;  3CWT A;  3F10 A;  1KG7 A;  2NOH A;  1WEF A;  1Q9U A;  4E9H A;  3OYF A;  1YTB A;  1LMZ A;  2OOX A;  1VOL B;  4EA4 A;  4YPR A;  1ORP A;  4EW0 A;  1PCM X;  1MUY A;  2YG8 A;  3VW4 A;  3IHO A;  1TUO A;  3OH6 A;  2OOY A;  1RRQ A;  1LWW A;  1QNA A;  2Z0F A;  1QN4 A;  2QRE A;  1R4X A;  1KEA A;  2QRD A;  3F0Z A;  3L2V A;  3DPU A;  1WQA A;  4E9G A;  1UL7 A;  5KL0 A;  1NH2 A;  1QTS A;  3NNQ A;  1VRL A;  1P5G X;  4E7L A;  2DKC A;  4ROE B;  4BDZ A;  2YA3 A;  4B22 A;  2H4L X;  2HZM A;  4BE2 A;  1HU0 A;  4HJH A;  3EIK A;  4E7K A;  2D0C A;  1QN5 A;  4AIA A;  4HSB A;  3OYJ A;  2DKA A;  1FN7 A;  1KY7 A;  4PY5 A;  2R5X A;  4WZS D;  3FHF A;  3OYB A;  2JHJ A;  3OYG A;  3DPT A;  1KFQ A;  2MZ8 A;  3OLP A;  4B21 A;  2FKF A;  3CW7 A;  1MPG A;  4AI5 A;  4NZG A;  1PU6 A;  5JN5 A;  1PU8 A;  3C04 A;  1N3C A;  2I5W A;  1ORN A;  1QN3 A;  4BE1 A;  2JG6 A;  1KG5 A;  3T4N A;  1KY6 A;  4YOQ A;  3OYL A;  1QN8 A;  4EAJ A;  4ZTJ A;  1UT7 A;  1J3M A;  4EAK A;  3OYC A;  2OFK A;  2JPI A;  1WEI A;  2NLV A;  1W80 A;  1WJW A;  3I3W A;  4EVV A;  1JFI C;  1PZD A;  4UOB A;  3BKQ X;  2NVM A;  1XQO A;  2EHB D;  3R2X C;  2HL8 A;  1YTF A;  1N39 A;  3L2U A;  1XSZ A;  3EAY A;  1TBA B;  3ASM A;  3S3M A;  2JHN A;  4EA5 A;  1NVP A;  2W03 A;  2HZS A;  1M3H A;  1YQR A;  3RSM A;  3OS1 A;  3D7Q A;  4E7I A;  4YPH A;  1YQM A;  5BMP A;  3I0W A;  2VJ0 A;  3ENO C;  2D0B A;  4PII A;  3OYA A;  4EJY A;  3I0X A;  4IL8 A;  1JDY A;  4DK9 A;  1LWY A;  4E7H A;  2MJ7 A;  1PVS A;  3KTU A;  2NOE A;  3FSP A;  1M3Q A;  4BAC A;  2V92 A;  3RPJ A;  5FRM A;  3OH9 A;  4UNF A;  2OFI A;  5DPK A;  2DKD A;  4ROD B;  4B24 A;  1DIZ A;  3CWA A;  2FGT A;  1QNB A;  1E42 A;  3N0U A;  1K35 A;  4DUL A;  2V75 A;  3CVS A;  1NKU A;  1EBM A;  3OS2 A;  1TBP A;  2HL9 A;  1KQJ A;  2V8Q A;  4TPS A;  5FRN A;  1P5D X;  1QN7 A;  1KG3 A;  2IV9 A;  4BDY A;  5JMV D;  3OGD A;  4CFF A;  2QRC A;  5IYB P;  2NOI A;  2ABK A;  4E7J A;  1KG4 A;  3N89 A;  3PMG A;  2NWV A;  3NA5 A;  2Z8U A;  1EUV A;  1NGN A;  3CWU A;  3UW2 A;  3PDK A;  2D0A A;  1VKL A;  2Y8L A;  4WXA A;  4IKF A;  1VTO A;  3G0Q A;  2YH5 A;  3OCI A;  4ROC B;  1KO9 A;  2V9J A;  3HS8 A;  1VTL E;  4AI4 A;  4E9F A;  3SNS A;  1M5Q 1;  3H1Z A;  4OFH A;  3TE5 A;  3ENC A;  2NOL A;  1RM1 A;  1QTP A;  5EPC A;  4Q11 A;  2FKM X;  1V5S A;  1C4G A;  5KN9 A;  3L2R A;  1XG7 A;  4BJU A;  1KYU A;  5BMN A;  3OYK A;  4D7Q A;  2H56 A;  1LWV A;  4EAG A;  1QN9 A;  1PU7 A;  1XQP A;  3OSE A;  4EAI A;  3HS9 A;  1U84 A;  2FUV A;  1TGH A;  3OYE A;  1VOK A;  4EJZ A;  3D4V A;  4EAL A;  4WX8 A;  1MUD A;  5KN8 A;  4ZTF A;  3OYN A;  1RRS A;  3OYD A;  1MUN A;  3LCN A;  3S6I A;  3CVT A;  2NOZ A;  4B23 A;  3FHG A;  1C9B B;  1KYD A;  5IYC P;  3TDH A;  1P59 A;  1QNE A;  3OC3 C;  5AN4 A;  3S3N A;  1QNC A; 
#chains in the Genus database with same CATH homology
 2OFK A;  3IHO A;  3OGD A;  1WEI A;  2NOB A;  1N3A A;  4EVV A;  3OH6 A;  1RRQ A;  4E9E A;  1LWW A;  2NOI A;  4UOB A;  2ABK A;  1KG4 A;  2XHI A;  1YQL A;  1KEA A;  1XQO A;  4EW4 A;  3F0Z A;  1NGN A;  3CWU A;  1N39 A;  1P7M A;  4E9G A;  1KG6 A;  2JHN A;  3G0Q A;  1VRL A;  1WEG A;  4EA5 A;  1YQK A;  1KO9 A;  4OFE A;  1M3H A;  4EA4 A;  4AI4 A;  4E9F A;  4B22 A;  4OFH A;  1YQR A;  1HU0 A;  2NOL A;  4YPH A;  2YG9 A;  1YQM A;  5KN9 A;  3I0W A;  1XG7 A;  3N5N X;  4PII A;  2H56 A;  4EJY A;  4AIA A;  3I0X A;  4HSB A;  1LWV A;  1FN7 A;  1PU7 A;  1XQP A;  4DK9 A;  1LWY A;  3CWS A;  3FHF A;  1PVS A;  3KTU A;  2NOE A;  3FSP A;  2NOF A;  1M3Q A;  2JHJ A;  4EJZ A;  3D4V A;  5CHZ A;  4B21 A;  3OH9 A;  4OFA A;  4UNF A;  1MUD A;  3IH7 A;  2OFI A;  5DPK A;  3CW7 A;  1MPG A;  4AI5 A;  5KN8 A;  1PU6 A;  3KNT A;  4B24 A;  1KG2 A;  1RRS A;  1DIZ A;  1MUN A;  3CWA A;  1PU8 A;  1N3C A;  2I5W A;  1ORN A;  3N0U A;  3S6I A;  2JG6 A;  3CVS A;  1NKU A;  1KG5 A;  3CVT A;  3CWT A;  3F10 A;  1EBM A;  4YOQ A;  1KG7 A;  2NOZ A;  2NOH A;  1WEF A;  4B23 A;  3FHG A;  1KQJ A;  4E9H A;  1P59 A;  1LMZ A;  1KG3 A;  5AN4 A;  4YPR A;  1ORP A;  4EW0 A;  1MUY A;  2YG8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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