2JHJA

3-methyladenine dna-glycosylase from archaeoglobus fulgidus
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
295
structure length
290
Chain Sequence
MWRIELKHAVNWELKMKFFVLPELPTPDVVESGVWRRAIVLDGRAVAVMAYPESERTIVVEGNFENREWEAVRRKLVEYLGLQNPEELYRFMDGDEKLRMLKNRFYGFGRAGLMSMSVFEGIAKAIIQQQISFVVAEKLAAKIVGRFGDEVEWNGLKFYGFPTQEAILKAGVEGLRECGLSRRKAELIVEIAKEENLEELKEWGEEEAYEYLTSFKGIGRWTAELVLSMALGKNVFPADDLGVRRAVSRLYFNGEIQSAEKVREIARERFGRFARDILFYLFLYDRFFSV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Enzymatic Excision of N1-Methyladenine and N3-Methylcytosine from DNA
pubmed doi rcsb
molecule tags Hydrolase
source organism Archaeoglobus fulgidus
molecule keywords 3-METHYLADENINE DNA-GLYCOSYLASE
total genus 102
structure length 290
sequence length 295
chains with identical sequence B
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 2jhjA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 2jhjA03
3.30.310.20 Alpha Beta 2-Layer Sandwich TATA-Binding Protein DNA-3-methyladenine glycosylase AlkA, N-terminal domain 2jhjA01
1KG6A 3I0WA 1FN7A 1LWYA 3G0QA 4EVVA 5AN4A 1VRLA 1MUYA 3CWUA 1LMZA 1XQOA 3I0XA 3CWSA 3OH9A 1YQMA 4B22A 2YG9A 1XQPA 3F10A 4EJZA 2NOLA 2NOIA 3CWAA 1P7MA 1WEFA 1YQRA 5KN8A 3KNTA 4AIAA 4HSBA 4OFAA 1KO9A 2NOFA 5KN9A 3F0ZA 4YOQA 1PU6A 1N39A 1KQJA 2H56A 4B24A 1HU0A 4EA4A 1WEGA 3CVSA 3IH7A 1EBMA 1KG4A 4OFEA 1LWVA 4E9FA 1YQLA 5CHZA 4EW4A 4UNFA 2NOBA 4E9EA 4B21A 3S6IA 1KG7A 4E9HA 1PU7A 1KEAA 2JHJA 1WEIA 2JHNA 3IHOA 1P59A 1N3AA 1MUNA 2XHIA 3CVTA 4EW0A 4DK9A 1YQKA 1KG2A 2NOEA 2ABKA 3OH6A 3FSPA 3CW7A 1MUDA 3KTUA 1NGNA 4EA5A 4E9GA 1PU8A 1ORNA 1M3HA 3OGDA 2I5WA 2NOZA 4EJYA 2JG6A 1NKUA 1MPGA 3N0UA 3CWTA 3N5NX 1XG7A 3D4VA 1KG5A 2NOHA 4UOBA 2OFIA 4PIIA 2OFKA 4YPRA 3FHGA 4OFHA 5DPKA 1RRQA 4YPHA 4B23A 1LWWA 1PVSA 4AI5A 1DIZA 3FHFA 1M3QA 1N3CA 1RRSA 4AI4A 1KG3A 2YG8A 1ORPA
chains in the Genus database with same CATH superfamily
1YTBA 4DULA 5AN4A 1VRLA 3OYKA 1XQOA 4B22A 1NVPA 1XQPA 2NOLA 1T6AA 2QR1A 2D0AA 1RM1A 3N89A 1YQRA 5KN8A 2IV9A 3VN5A 1AISA 4AIAA 4HSBA 2NOFA 3F0ZA 1NGMA 1QNEA 2F7LA 4ZTFA 4EA4A 1WEGA 4EAIA 3RSMA 1EBMA 2IV8A 2V92A 3PMGA 2HZSA 4WZSD 3EIKA 2FKMX 1KG7A 1CDWA 2YA3A 1PU7A 1KEAA 1WEIA 4E7LA 1C47A 2QREA 3D7QA 4E7JA 5EPCA 1N3AA 1QNBA 2NWVA 1D3UA 1E42A 1M5Q1 1KG2A 3CW7A 3KTUA 4NZGA 2W04A 2JOIA 1MP9A 3L2UA 2V9JA 3D4VA 3R2XC 4YPRA 4BACA 4BDZA 2LAEA 4I8OA 4YPHA 3ASMA 4E7HA 1QN5A 4AI5A 1VTOA 1M3QA 1N3CA 2O3OA 4AI4A 1KY7A 3SNSA 1ORPA 4C7PA 1KG6A 3G0QA 1QNCA 4D7QA 1LMZA 4D7RA 1YQMA 5JMVD 4EJZA 3NA5A 1TBAB 1K35A 1WEFA 5F9CA 3KNTA 4ZTJA 3OYHA 2EHBD 2Z8UA 1B9KA 1PU6A 1N39A 2H56A 3IH7A 4OFEA 3ENOC 3HS9A 1KFQA 4EW4A 2OOYA 3L2VA 2NOBA 4E7KA 2QRCA 1KY6A 3S6IA 1UT7A 2QRDA 3EAYA 4TPSA 2JHJA 1K2YX 1KYDA 1VOLB 3IHOA 2D0CA 3OYEA 1MUNA 3CVTA 5FRNA 5IYBP 1QTPA 4BJUA 4EW0A 3KRMA 2HL8A 2ABKA 3OYAA 1P5DX 3OYMA 4E9GA 2V75A 3OYIA 2NOZA 2JG6A 1MPGA 3N0UA 1JFIC 1QN8A 2OFKA 2R5XA 2Y8LA 3FHGA 1C9BB 4IKFA 1KFIA 4ROCB 4QG5A 3OYJA 4ROEB 1QNAA 3DPUA 1TBPA 1RRSA 1YTFA 3OC3C 1KG3A 4BDYA 1PZDA 1FN7A 2H4LX 2HZMA 4EVVA 3OYFA 2MZ8A 1MUYA 1XSZA 2Z0FA 1TGHA 4EAKA 3S3NA 5IYDP 3OLPA 3OH9A 1KYFA 3OS2A 2YG9A 2D0BA 2DKAA 1UL7A 3OSMA 1JDYA 2G30A 2YH5A 2NOIA 1P7MA 2DKDA 3PDKA 3L2RA 2DKCA 1NH2A 2W03A 3H1ZA 4OFAA 5KN9A 1QTSA 4YOQA 1U84A 2VJ0A 3OYDA 2NLVA 5IYCP 1TUOA 3TE5A 1QN9A 2JPSA 2H5AX 3OSTA 4EAGA 5JN5A 4E9FA 5CHZA 3OYNA 4UNFA 2NVMA 2FGTA 1WJWA 1EUVA 3OSEA 4B21A 1QN3A 4E9HA 1VOKA 3OCIA 2FKFA 1QN7A 1QN4A 3BKQX 2XHIA 4MRQA 4DK9A 2NOEA 1J3MA 3FSPA 2MJ7A 1NGNA 3OGDA 3I3WA 2I5WA 1QN6A 2QLVA 5KL0A 1PCZA 5FROA 1R4XA 3CWTA 1XG7A 3OY9A 2NOHA 5BMPA 4UOBA 1UT4A 4OFHA 1C4GA 5DPKA 3OS1A 4WXAA 3S3MA 4PY5A 1LXTA 4B23A 1PCMX 1DIZA 1V5SA 3FHFA 5HSHA 2ZFDB 2YG8A 3I0WA 1LWYA 3L2QA 5BMNA 4CFFA 3C04A 3ENCA 2Y8QA 3CWUA 1KYUA 2OOXA 4B0AA 3I0XA 3CWSA 4Q11A 4IL8A 3F10A 3CWAA 3DPTA 1VTLE 1KO9A 2HKPA 4EALA 3T4NA 1KQJA 4B24A 1HU0A 3CVSA 3OYBA 1W80A 1KG4A 1LWVA 1YQLA 3VW4A 4WX8A 4E9EA 3UW2A 3OS0A 4BE1A 3ULXA 2JHNA 1P59A 1P5GX 4HJHA 3OYLA 1WQAA 3OYCA 3LCNA 4RODB 1YQKA 3OH6A 1Q9UA 4BE0A 1MUDA 4BE2A 4EA5A 3OYGA 2FUVA 1ORNA 1PU8A 1M3HA 1PCJX 3TDHA 2JPIA 2V8QA 4EJYA 1NKUA 3S3OA 4EAJA 3RPJA 3N5NX 1KG5A 3HS8A 1VKLA 2OFIA 4PIIA 1RRQA 3NNQA 2HL9A 1LWWA 1PVSA 5FRMA 3L2WA 4E7IA 2PWWA
chains in the Genus database with same CATH topology
1KG6A 3I0WA 1FN7A 1LWYA 3G0QA 4EVVA 5AN4A 1VRLA 1MUYA 3CWUA 1LMZA 1XQOA 3I0XA 3CWSA 3OH9A 1YQMA 4B22A 2YG9A 1XQPA 3F10A 4EJZA 2NOLA 2NOIA 3CWAA 1P7MA 1WEFA 1YQRA 5KN8A 3KNTA 4AIAA 4HSBA 4OFAA 1KO9A 2NOFA 5KN9A 3F0ZA 4YOQA 1PU6A 1N39A 1KQJA 2H56A 4B24A 1HU0A 4EA4A 1WEGA 3CVSA 3IH7A 1EBMA 1KG4A 4OFEA 1LWVA 4E9FA 1YQLA 5CHZA 4EW4A 4UNFA 2NOBA 4E9EA 4B21A 3S6IA 1KG7A 4E9HA 1PU7A 1KEAA 2JHJA 1WEIA 2JHNA 3IHOA 1P59A 1N3AA 1MUNA 2XHIA 3CVTA 4EW0A 4DK9A 1YQKA 1KG2A 2NOEA 2ABKA 3OH6A 3FSPA 3CW7A 1MUDA 3KTUA 1NGNA 4EA5A 4E9GA 1PU8A 1ORNA 1M3HA 3OGDA 2I5WA 2NOZA 4EJYA 2JG6A 1NKUA 1MPGA 3N0UA 3CWTA 3N5NX 1XG7A 3D4VA 1KG5A 2NOHA 4UOBA 2OFIA 4PIIA 2OFKA 4YPRA 3FHGA 4OFHA 5DPKA 1RRQA 4YPHA 4B23A 1LWWA 1PVSA 4AI5A 1DIZA 3FHFA 1M3QA 1N3CA 1RRSA 4AI4A 1KG3A 2YG8A 1ORPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KG6 A;  3I0W A;  1FN7 A;  1LWY A;  3G0Q A;  4EVV A;  5AN4 A;  1VRL A;  1MUY A;  3CWU A;  1LMZ A;  1XQO A;  3I0X A;  3CWS A;  3OH9 A;  1YQM A;  4B22 A;  2YG9 A;  1XQP A;  3F10 A;  4EJZ A;  2NOL A;  2NOI A;  3CWA A;  1P7M A;  1WEF A;  1YQR A;  5KN8 A;  3KNT A;  4AIA A;  4HSB A;  4OFA A;  1KO9 A;  2NOF A;  5KN9 A;  3F0Z A;  4YOQ A;  1PU6 A;  1N39 A;  1KQJ A;  2H56 A;  4B24 A;  1HU0 A;  4EA4 A;  1WEG A;  3CVS A;  3IH7 A;  1EBM A;  1KG4 A;  4OFE A;  1LWV A;  4E9F A;  1YQL A;  5CHZ A;  4EW4 A;  4UNF A;  2NOB A;  4E9E A;  4B21 A;  3S6I A;  1KG7 A;  4E9H A;  1PU7 A;  1KEA A;  2JHJ A;  1WEI A;  2JHN A;  3IHO A;  1P59 A;  1N3A A;  1MUN A;  2XHI A;  3CVT A;  4EW0 A;  4DK9 A;  1YQK A;  1KG2 A;  2NOE A;  2ABK A;  3OH6 A;  3FSP A;  3CW7 A;  1MUD A;  3KTU A;  1NGN A;  4EA5 A;  4E9G A;  1PU8 A;  1ORN A;  1M3H A;  3OGD A;  2I5W A;  2NOZ A;  4EJY A;  2JG6 A;  1NKU A;  1MPG A;  3N0U A;  3CWT A;  3N5N X;  1XG7 A;  3D4V A;  1KG5 A;  2NOH A;  4UOB A;  2OFI A;  4PII A;  2OFK A;  4YPR A;  3FHG A;  4OFH A;  5DPK A;  1RRQ A;  4YPH A;  4B23 A;  1LWW A;  1PVS A;  4AI5 A;  1DIZ A;  3FHF A;  1M3Q A;  1N3C A;  1RRS A;  4AI4 A;  1KG3 A;  2YG8 A;  1ORP A; 
#chains in the Genus database with same CATH topology
 1YTB A;  4DUL A;  5AN4 A;  1VRL A;  3OYK A;  1XQO A;  4B22 A;  1NVP A;  1XQP A;  2NOL A;  1T6A A;  2QR1 A;  2D0A A;  1RM1 A;  3N89 A;  1YQR A;  5KN8 A;  2IV9 A;  3VN5 A;  1AIS A;  4AIA A;  4HSB A;  2NOF A;  3F0Z A;  1NGM A;  1QNE A;  2F7L A;  4ZTF A;  4EA4 A;  1WEG A;  4EAI A;  3RSM A;  1EBM A;  2IV8 A;  2V92 A;  3PMG A;  2HZS A;  4WZS D;  3EIK A;  2FKM X;  1KG7 A;  1CDW A;  2YA3 A;  1PU7 A;  1KEA A;  1WEI A;  4E7L A;  1C47 A;  2QRE A;  3D7Q A;  4E7J A;  5EPC A;  1N3A A;  1QNB A;  2NWV A;  1D3U A;  1E42 A;  1M5Q 1;  1KG2 A;  3CW7 A;  3KTU A;  4NZG A;  2W04 A;  2JOI A;  1MP9 A;  3L2U A;  2V9J A;  3D4V A;  3R2X C;  4YPR A;  4BAC A;  4BDZ A;  2LAE A;  4I8O A;  4YPH A;  3ASM A;  4E7H A;  1QN5 A;  4AI5 A;  1VTO A;  1M3Q A;  1N3C A;  2O3O A;  4AI4 A;  1KY7 A;  3SNS A;  1ORP A;  4C7P A;  1KG6 A;  3G0Q A;  1QNC A;  4D7Q A;  1LMZ A;  4D7R A;  1YQM A;  5JMV D;  4EJZ A;  3NA5 A;  1TBA B;  1K35 A;  1WEF A;  5F9C A;  3KNT A;  4ZTJ A;  3OYH A;  2EHB D;  2Z8U A;  1B9K A;  1PU6 A;  1N39 A;  2H56 A;  3IH7 A;  4OFE A;  3ENO C;  3HS9 A;  1KFQ A;  4EW4 A;  2OOY A;  3L2V A;  2NOB A;  4E7K A;  2QRC A;  1KY6 A;  3S6I A;  1UT7 A;  2QRD A;  3EAY A;  4TPS A;  2JHJ A;  1K2Y X;  1KYD A;  1VOL B;  3IHO A;  2D0C A;  3OYE A;  1MUN A;  3CVT A;  5FRN A;  5IYB P;  1QTP A;  4BJU A;  4EW0 A;  3KRM A;  2HL8 A;  2ABK A;  3OYA A;  1P5D X;  3OYM A;  4E9G A;  2V75 A;  3OYI A;  2NOZ A;  2JG6 A;  1MPG A;  3N0U A;  1JFI C;  1QN8 A;  2OFK A;  2R5X A;  2Y8L A;  3FHG A;  1C9B B;  4IKF A;  1KFI A;  4ROC B;  4QG5 A;  3OYJ A;  4ROE B;  1QNA A;  3DPU A;  1TBP A;  1RRS A;  1YTF A;  3OC3 C;  1KG3 A;  4BDY A;  1PZD A;  1FN7 A;  2H4L X;  2HZM A;  4EVV A;  3OYF A;  2MZ8 A;  1MUY A;  1XSZ A;  2Z0F A;  1TGH A;  4EAK A;  3S3N A;  5IYD P;  3OLP A;  3OH9 A;  1KYF A;  3OS2 A;  2YG9 A;  2D0B A;  2DKA A;  1UL7 A;  3OSM A;  1JDY A;  2G30 A;  2YH5 A;  2NOI A;  1P7M A;  2DKD A;  3PDK A;  3L2R A;  2DKC A;  1NH2 A;  2W03 A;  3H1Z A;  4OFA A;  5KN9 A;  1QTS A;  4YOQ A;  1U84 A;  2VJ0 A;  3OYD A;  2NLV A;  5IYC P;  1TUO A;  3TE5 A;  1QN9 A;  2JPS A;  2H5A X;  3OST A;  4EAG A;  5JN5 A;  4E9F A;  5CHZ A;  3OYN A;  4UNF A;  2NVM A;  2FGT A;  1WJW A;  1EUV A;  3OSE A;  4B21 A;  1QN3 A;  4E9H A;  1VOK A;  3OCI A;  2FKF A;  1QN7 A;  1QN4 A;  3BKQ X;  2XHI A;  4MRQ A;  4DK9 A;  2NOE A;  1J3M A;  3FSP A;  2MJ7 A;  1NGN A;  3OGD A;  3I3W A;  2I5W A;  1QN6 A;  2QLV A;  5KL0 A;  1PCZ A;  5FRO A;  1R4X A;  3CWT A;  1XG7 A;  3OY9 A;  2NOH A;  5BMP A;  4UOB A;  1UT4 A;  4OFH A;  1C4G A;  5DPK A;  3OS1 A;  4WXA A;  3S3M A;  4PY5 A;  1LXT A;  4B23 A;  1PCM X;  1DIZ A;  1V5S A;  3FHF A;  5HSH A;  2ZFD B;  2YG8 A;  3I0W A;  1LWY A;  3L2Q A;  5BMN A;  4CFF A;  3C04 A;  3ENC A;  2Y8Q A;  3CWU A;  1KYU A;  2OOX A;  4B0A A;  3I0X A;  3CWS A;  4Q11 A;  4IL8 A;  3F10 A;  3CWA A;  3DPT A;  1VTL E;  1KO9 A;  2HKP A;  4EAL A;  3T4N A;  1KQJ A;  4B24 A;  1HU0 A;  3CVS A;  3OYB A;  1W80 A;  1KG4 A;  1LWV A;  1YQL A;  3VW4 A;  4WX8 A;  4E9E A;  3UW2 A;  3OS0 A;  4BE1 A;  3ULX A;  2JHN A;  1P59 A;  1P5G X;  4HJH A;  3OYL A;  1WQA A;  3OYC A;  3LCN A;  4ROD B;  1YQK A;  3OH6 A;  1Q9U A;  4BE0 A;  1MUD A;  4BE2 A;  4EA5 A;  3OYG A;  2FUV A;  1ORN A;  1PU8 A;  1M3H A;  1PCJ X;  3TDH A;  2JPI A;  2V8Q A;  4EJY A;  1NKU A;  3S3O A;  4EAJ A;  3RPJ A;  3N5N X;  1KG5 A;  3HS8 A;  1VKL A;  2OFI A;  4PII A;  1RRQ A;  3NNQ A;  2HL9 A;  1LWW A;  1PVS A;  5FRM A;  3L2W A;  4E7I A;  2PWW A; 
#chains in the Genus database with same CATH homology
 1KG6 A;  3I0W A;  1FN7 A;  1LWY A;  3G0Q A;  4EVV A;  5AN4 A;  1VRL A;  1MUY A;  3CWU A;  1LMZ A;  1XQO A;  3I0X A;  3CWS A;  3OH9 A;  1YQM A;  4B22 A;  2YG9 A;  1XQP A;  3F10 A;  4EJZ A;  2NOL A;  2NOI A;  3CWA A;  1P7M A;  1WEF A;  1YQR A;  5KN8 A;  3KNT A;  4AIA A;  4HSB A;  4OFA A;  1KO9 A;  2NOF A;  5KN9 A;  3F0Z A;  4YOQ A;  1PU6 A;  1N39 A;  1KQJ A;  2H56 A;  4B24 A;  1HU0 A;  4EA4 A;  1WEG A;  3CVS A;  3IH7 A;  1EBM A;  1KG4 A;  4OFE A;  1LWV A;  4E9F A;  1YQL A;  5CHZ A;  4EW4 A;  4UNF A;  2NOB A;  4E9E A;  4B21 A;  3S6I A;  1KG7 A;  4E9H A;  1PU7 A;  1KEA A;  2JHJ A;  1WEI A;  2JHN A;  3IHO A;  1P59 A;  1N3A A;  1MUN A;  2XHI A;  3CVT A;  4EW0 A;  4DK9 A;  1YQK A;  1KG2 A;  2NOE A;  2ABK A;  3OH6 A;  3FSP A;  3CW7 A;  1MUD A;  3KTU A;  1NGN A;  4EA5 A;  4E9G A;  1PU8 A;  1ORN A;  1M3H A;  3OGD A;  2I5W A;  2NOZ A;  4EJY A;  2JG6 A;  1NKU A;  1MPG A;  3N0U A;  3CWT A;  3N5N X;  1XG7 A;  3D4V A;  1KG5 A;  2NOH A;  4UOB A;  2OFI A;  4PII A;  2OFK A;  4YPR A;  3FHG A;  4OFH A;  5DPK A;  1RRQ A;  4YPH A;  4B23 A;  1LWW A;  1PVS A;  4AI5 A;  1DIZ A;  3FHF A;  1M3Q A;  1N3C A;  1RRS A;  4AI4 A;  1KG3 A;  2YG8 A;  1ORP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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