2JHNA

3-methyladenine dna-glycosylase from archaeoglobus fulgidus
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
295
structure length
293
Chain Sequence
MWRIELKHAVNWELKMKFFVLPELPTPDVVESGVWRRAIVLDGRAVAVMAYPESERTIVVEGNFENREWEAVRRKLVEYLGLQNPEELYRFMDGDEKLRMLKNRFYGFGRAGLMSMSVFEGIAKAIIQQQISFVVAEKLAAKIVGRFGDEVEWNGLKFYGFPTQEAILKAGVEGLRECGLSRRKAELIVEIAKEENLEELKEWGEEEAYEYLTSFKGIGRWTAELVLSIALGKNVFPADDLGVRRAVSRLYFNGEIQSAEKVREIARERFGRFARDILFYLFLYDRFFSKELV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Enzymatic Excision of N1-Methyladenine and N3-Methylcytosine from DNA
pubmed doi rcsb
molecule tags Hydrolase
source organism Archaeoglobus fulgidus
molecule keywords 3-METHYLADENINE DNA-GLYCOSYLASE
total genus 103
structure length 293
sequence length 295
chains with identical sequence B
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 2jhnA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 2jhnA03
3.30.310.20 Alpha Beta 2-Layer Sandwich TATA-Binding Protein DNA-3-methyladenine glycosylase AlkA, N-terminal domain 2jhnA01
2XHIA 3CVSA 4E9FA 1LWWA 4EA5A 1WEFA 1PU6A 5AN4A 1ORPA 4B21A 1KG6A 1N39A 1LWVA 3N0UA 1VRLA 1MUDA 1MPGA 4AIAA 2ABKA 1M3QA 4DK9A 1YQKA 3F10A 4EJZA 1WEGA 2JG6A 3CWUA 1KG5A 3FHFA 1WEIA 2NOZA 2H56A 2YG9A 1MUNA 3I0WA 1XG7A 4OFAA 1EBMA 2NOFA 3CVTA 3IH7A 1M3HA 1RRSA 4UNFA 5KN9A 5DPKA 2I5WA 1KG3A 4AI5A 1KG7A 1XQOA 5CHZA 3OGDA 4OFEA 1P59A 1KEAA 3KTUA 5KN8A 2NOIA 4EVVA 2NOHA 4YPHA 4B23A 4UOBA 3S6IA 4EW0A 4EA4A 1DIZA 3KNTA 2NOLA 2OFIA 3N5NX 4OFHA 2OFKA 3IHOA 1HU0A 1RRQA 1P7MA 3CWSA 3D4VA 1KO9A 1FN7A 3CW7A 3CWTA 1ORNA 4AI4A 3OH9A 2NOBA 1YQRA 2JHJA 3G0QA 1LWYA 1NKUA 4YOQA 4YPRA 3FHGA 1LMZA 4E9HA 4E9EA 1N3AA 4B24A 3F0ZA 4EJYA 1YQLA 4E9GA 1NGNA 3I0XA 2JHNA 1PU7A 1N3CA 3CWAA 4HSBA 3OH6A 1PVSA 1XQPA 4B22A 1PU8A 1KG2A 3FSPA 4EW4A 1KG4A 2YG8A 2NOEA 1MUYA 4PIIA 1KQJA 1YQMA
chains in the Genus database with same CATH superfamily
1E42A 3CVSA 3TE5A 4EAKA 2FKFA 1LWWA 3ULXA 1WEFA 5F9CA 3OYGA 1VRLA 4AIAA 1UL7A 4DK9A 2FGTA 1PCZA 3CWUA 2NOZA 3S3MA 1QN5A 3I0WA 3OSTA 4OFAA 4I8OA 3OCIA 3OYEA 1KY7A 2Z8UA 1D3UA 4E7IA 4BDYA 2FUVA 1TBAB 4OFEA 5KN8A 2NOLA 3OYFA 2OFIA 3N5NX 2W04A 2NVMA 3RSMA 1QN7A 3D4VA 1VOKA 1M5Q1 3OH9A 3VW4A 1YQRA 4WZSD 3SNSA 2JHJA 1LWYA 3OS1A 5BMPA 1YTFA 1N3AA 4ROEB 3I3WA 2JPSA 1K2YX 3S3OA 4HSBA 3OSMA 1KG2A 3FSPA 4E7KA 4PIIA 1KQJA 2D0CA 2W03A 2MJ7A 3PDKA 3OYKA 2HL9A 1LXTA 3DPUA 5AN4A 1U84A 1KYFA 1VKLA 4EAIA 1WJWA 1J3MA 2ABKA 2DKCA 5JN5A 4DULA 1EUVA 3OYBA 1NH2A 3F10A 4EAGA 3OS0A 4EJZA 3OS2A 4RODB 1KG5A 3FHFA 1B9KA 3EAYA 1KYUA 4Q11A 3HS8A 4WXAA 1RRSA 3HS9A 4UNFA 2NWVA 5KN9A 1QN6A 2ZFDB 5DPKA 1KY6A 3OYAA 3OYHA 1R4XA 2V75A 1P59A 1KEAA 1YTBA 4EVVA 2NOHA 4UOBA 2O3OA 3S6IA 5JMVD 1C9BB 4OFHA 3IHOA 1HU0A 3T4NA 1RRQA 3CWSA 1FN7A 3CW7A 3PMGA 3CWTA 5IYDP 1ORNA 4HJHA 1P5GX 5HSHA 1KYDA 1NKUA 1LMZA 4B24A 4CFFA 2FKMX 5IYCP 2OOYA 4E9GA 2DKDA 4EALA 1JFIC 3CWAA 2Y8QA 2Z0FA 1TUOA 1PVSA 4B22A 3OYMA 1WQAA 4MRQA 3BKQX 4BE2A 1C47A 1MUYA 1VTLE 3D7QA 4D7QA 2QR1A 1QN9A 1TGHA 1YQMA 3OC3C 1JDYA 2XHIA 5IYBP 3LCNA 4E9FA 4ZTFA 1UT7A 4IKFA 2YA3A 1QTPA 4B21A 1LWVA 4BE1A 1QNBA 4BE0A 1MUDA 3NA5A 1M3QA 1VTOA 1YQKA 2JPIA 1K35A 2QRDA 2H56A 2YG9A 2V9JA 2IV8A 5EPCA 2V92A 1EBMA 3OLPA 2NLVA 4IL8A 2H5AX 4NZGA 2F7LA 1CDWA 2IV9A 3OYJA 2JOIA 1KG7A 1C4GA 5FRMA 2NOIA 4B23A 3L2UA 4EW0A 4EA4A 1DIZA 3OYIA 3S3NA 4D7RA 2QREA 4WX8A 1MP9A 3OYDA 4ROCB 1QN3A 4AI4A 3ENCA 3VN5A 2NOBA 4BJUA 4BDZA 3R2XC 2HZMA 3OYNA 4E7HA 3G0QA 4YOQA 4YPRA 3FHGA 4E9HA 5BMNA 2VJ0A 4EAJA 4EJYA 1YQLA 3I0XA 2HL8A 1QN8A 1XSZA 1PU7A 1N3CA 1P5DX 2MZ8A 1NVPA 3OH6A 1XQPA 3NNQA 2YH5A 3L2VA 4EW4A 1KG4A 2OOXA 2YG8A 2NOEA 2H4LX 5KL0A 2D0BA 4B0AA 3ENOC 3L2WA 1QNCA 2LAEA 5FRNA 4EA5A 3OY9A 1PU6A 2V8QA 1ORPA 1PCMX 1KG6A 1N39A 1TBPA 3N0UA 1T6AA 2EHBD 1MPGA 2PWWA 2HKPA 3ASMA 1AISA 3OSEA 2QRCA 4TPSA 2HZSA 4PY5A 4BACA 1NGMA 1WEGA 2JG6A 3TDHA 1KFIA 1WEIA 5FROA 3RPJA 1MUNA 1XG7A 1PZDA 2NOFA 3CVTA 2DKAA 3IH7A 1PCJX 1M3HA 4QG5A 1QNAA 4E7LA 1VOLB 1QN4A 3N89A 2I5WA 4ZTJA 1KG3A 1Q9UA 1RM1A 4AI5A 5CHZA 1XQOA 3OGDA 3L2QA 3KTUA 4YPHA 1KFQA 2R5XA 3KNTA 1UT4A 1QTSA 3OYLA 2D0AA 2OFKA 1P7MA 1KO9A 4E7JA 3C04A 1QNEA 3KRMA 1V5SA 3L2RA 4E9EA 2G30A 4C7PA 3F0ZA 2QLVA 1W80A 1NGNA 3OYCA 2JHNA 1PU8A 2Y8LA 3DPTA 3EIKA 3H1ZA 3UW2A
chains in the Genus database with same CATH topology
2XHIA 3CVSA 4E9FA 1LWWA 4EA5A 1WEFA 1PU6A 5AN4A 1ORPA 4B21A 1KG6A 1N39A 1LWVA 3N0UA 1VRLA 1MUDA 1MPGA 4AIAA 2ABKA 1M3QA 4DK9A 1YQKA 3F10A 4EJZA 1WEGA 2JG6A 3CWUA 1KG5A 3FHFA 1WEIA 2NOZA 2H56A 2YG9A 1MUNA 3I0WA 1XG7A 4OFAA 1EBMA 2NOFA 3CVTA 3IH7A 1M3HA 1RRSA 4UNFA 5KN9A 5DPKA 2I5WA 1KG3A 4AI5A 1KG7A 1XQOA 5CHZA 3OGDA 4OFEA 1P59A 1KEAA 3KTUA 5KN8A 2NOIA 4EVVA 2NOHA 4YPHA 4B23A 4UOBA 3S6IA 4EW0A 4EA4A 1DIZA 3KNTA 2NOLA 2OFIA 3N5NX 4OFHA 2OFKA 3IHOA 1HU0A 1RRQA 1P7MA 3CWSA 3D4VA 1KO9A 1FN7A 3CW7A 3CWTA 1ORNA 4AI4A 3OH9A 2NOBA 1YQRA 2JHJA 3G0QA 1LWYA 1NKUA 4YOQA 4YPRA 3FHGA 1LMZA 4E9HA 4E9EA 1N3AA 4B24A 3F0ZA 4EJYA 1YQLA 4E9GA 1NGNA 3I0XA 2JHNA 1PU7A 1N3CA 3CWAA 4HSBA 3OH6A 1PVSA 1XQPA 4B22A 1PU8A 1KG2A 3FSPA 4EW4A 1KG4A 2YG8A 2NOEA 1MUYA 4PIIA 1KQJA 1YQMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XHI A;  3CVS A;  4E9F A;  1LWW A;  4EA5 A;  1WEF A;  1PU6 A;  5AN4 A;  1ORP A;  4B21 A;  1KG6 A;  1N39 A;  1LWV A;  3N0U A;  1VRL A;  1MUD A;  1MPG A;  4AIA A;  2ABK A;  1M3Q A;  4DK9 A;  1YQK A;  3F10 A;  4EJZ A;  1WEG A;  2JG6 A;  3CWU A;  1KG5 A;  3FHF A;  1WEI A;  2NOZ A;  2H56 A;  2YG9 A;  1MUN A;  3I0W A;  1XG7 A;  4OFA A;  1EBM A;  2NOF A;  3CVT A;  3IH7 A;  1M3H A;  1RRS A;  4UNF A;  5KN9 A;  5DPK A;  2I5W A;  1KG3 A;  4AI5 A;  1KG7 A;  1XQO A;  5CHZ A;  3OGD A;  4OFE A;  1P59 A;  1KEA A;  3KTU A;  5KN8 A;  2NOI A;  4EVV A;  2NOH A;  4YPH A;  4B23 A;  4UOB A;  3S6I A;  4EW0 A;  4EA4 A;  1DIZ A;  3KNT A;  2NOL A;  2OFI A;  3N5N X;  4OFH A;  2OFK A;  3IHO A;  1HU0 A;  1RRQ A;  1P7M A;  3CWS A;  3D4V A;  1KO9 A;  1FN7 A;  3CW7 A;  3CWT A;  1ORN A;  4AI4 A;  3OH9 A;  2NOB A;  1YQR A;  2JHJ A;  3G0Q A;  1LWY A;  1NKU A;  4YOQ A;  4YPR A;  3FHG A;  1LMZ A;  4E9H A;  4E9E A;  1N3A A;  4B24 A;  3F0Z A;  4EJY A;  1YQL A;  4E9G A;  1NGN A;  3I0X A;  2JHN A;  1PU7 A;  1N3C A;  3CWA A;  4HSB A;  3OH6 A;  1PVS A;  1XQP A;  4B22 A;  1PU8 A;  1KG2 A;  3FSP A;  4EW4 A;  1KG4 A;  2YG8 A;  2NOE A;  1MUY A;  4PII A;  1KQJ A;  1YQM A; 
#chains in the Genus database with same CATH topology
 1E42 A;  3CVS A;  3TE5 A;  4EAK A;  2FKF A;  1LWW A;  3ULX A;  1WEF A;  5F9C A;  3OYG A;  1VRL A;  4AIA A;  1UL7 A;  4DK9 A;  2FGT A;  1PCZ A;  3CWU A;  2NOZ A;  3S3M A;  1QN5 A;  3I0W A;  3OST A;  4OFA A;  4I8O A;  3OCI A;  3OYE A;  1KY7 A;  2Z8U A;  1D3U A;  4E7I A;  4BDY A;  2FUV A;  1TBA B;  4OFE A;  5KN8 A;  2NOL A;  3OYF A;  2OFI A;  3N5N X;  2W04 A;  2NVM A;  3RSM A;  1QN7 A;  3D4V A;  1VOK A;  1M5Q 1;  3OH9 A;  3VW4 A;  1YQR A;  4WZS D;  3SNS A;  2JHJ A;  1LWY A;  3OS1 A;  5BMP A;  1YTF A;  1N3A A;  4ROE B;  3I3W A;  2JPS A;  1K2Y X;  3S3O A;  4HSB A;  3OSM A;  1KG2 A;  3FSP A;  4E7K A;  4PII A;  1KQJ A;  2D0C A;  2W03 A;  2MJ7 A;  3PDK A;  3OYK A;  2HL9 A;  1LXT A;  3DPU A;  5AN4 A;  1U84 A;  1KYF A;  1VKL A;  4EAI A;  1WJW A;  1J3M A;  2ABK A;  2DKC A;  5JN5 A;  4DUL A;  1EUV A;  3OYB A;  1NH2 A;  3F10 A;  4EAG A;  3OS0 A;  4EJZ A;  3OS2 A;  4ROD B;  1KG5 A;  3FHF A;  1B9K A;  3EAY A;  1KYU A;  4Q11 A;  3HS8 A;  4WXA A;  1RRS A;  3HS9 A;  4UNF A;  2NWV A;  5KN9 A;  1QN6 A;  2ZFD B;  5DPK A;  1KY6 A;  3OYA A;  3OYH A;  1R4X A;  2V75 A;  1P59 A;  1KEA A;  1YTB A;  4EVV A;  2NOH A;  4UOB A;  2O3O A;  3S6I A;  5JMV D;  1C9B B;  4OFH A;  3IHO A;  1HU0 A;  3T4N A;  1RRQ A;  3CWS A;  1FN7 A;  3CW7 A;  3PMG A;  3CWT A;  5IYD P;  1ORN A;  4HJH A;  1P5G X;  5HSH A;  1KYD A;  1NKU A;  1LMZ A;  4B24 A;  4CFF A;  2FKM X;  5IYC P;  2OOY A;  4E9G A;  2DKD A;  4EAL A;  1JFI C;  3CWA A;  2Y8Q A;  2Z0F A;  1TUO A;  1PVS A;  4B22 A;  3OYM A;  1WQA A;  4MRQ A;  3BKQ X;  4BE2 A;  1C47 A;  1MUY A;  1VTL E;  3D7Q A;  4D7Q A;  2QR1 A;  1QN9 A;  1TGH A;  1YQM A;  3OC3 C;  1JDY A;  2XHI A;  5IYB P;  3LCN A;  4E9F A;  4ZTF A;  1UT7 A;  4IKF A;  2YA3 A;  1QTP A;  4B21 A;  1LWV A;  4BE1 A;  1QNB A;  4BE0 A;  1MUD A;  3NA5 A;  1M3Q A;  1VTO A;  1YQK A;  2JPI A;  1K35 A;  2QRD A;  2H56 A;  2YG9 A;  2V9J A;  2IV8 A;  5EPC A;  2V92 A;  1EBM A;  3OLP A;  2NLV A;  4IL8 A;  2H5A X;  4NZG A;  2F7L A;  1CDW A;  2IV9 A;  3OYJ A;  2JOI A;  1KG7 A;  1C4G A;  5FRM A;  2NOI A;  4B23 A;  3L2U A;  4EW0 A;  4EA4 A;  1DIZ A;  3OYI A;  3S3N A;  4D7R A;  2QRE A;  4WX8 A;  1MP9 A;  3OYD A;  4ROC B;  1QN3 A;  4AI4 A;  3ENC A;  3VN5 A;  2NOB A;  4BJU A;  4BDZ A;  3R2X C;  2HZM A;  3OYN A;  4E7H A;  3G0Q A;  4YOQ A;  4YPR A;  3FHG A;  4E9H A;  5BMN A;  2VJ0 A;  4EAJ A;  4EJY A;  1YQL A;  3I0X A;  2HL8 A;  1QN8 A;  1XSZ A;  1PU7 A;  1N3C A;  1P5D X;  2MZ8 A;  1NVP A;  3OH6 A;  1XQP A;  3NNQ A;  2YH5 A;  3L2V A;  4EW4 A;  1KG4 A;  2OOX A;  2YG8 A;  2NOE A;  2H4L X;  5KL0 A;  2D0B A;  4B0A A;  3ENO C;  3L2W A;  1QNC A;  2LAE A;  5FRN A;  4EA5 A;  3OY9 A;  1PU6 A;  2V8Q A;  1ORP A;  1PCM X;  1KG6 A;  1N39 A;  1TBP A;  3N0U A;  1T6A A;  2EHB D;  1MPG A;  2PWW A;  2HKP A;  3ASM A;  1AIS A;  3OSE A;  2QRC A;  4TPS A;  2HZS A;  4PY5 A;  4BAC A;  1NGM A;  1WEG A;  2JG6 A;  3TDH A;  1KFI A;  1WEI A;  5FRO A;  3RPJ A;  1MUN A;  1XG7 A;  1PZD A;  2NOF A;  3CVT A;  2DKA A;  3IH7 A;  1PCJ X;  1M3H A;  4QG5 A;  1QNA A;  4E7L A;  1VOL B;  1QN4 A;  3N89 A;  2I5W A;  4ZTJ A;  1KG3 A;  1Q9U A;  1RM1 A;  4AI5 A;  5CHZ A;  1XQO A;  3OGD A;  3L2Q A;  3KTU A;  4YPH A;  1KFQ A;  2R5X A;  3KNT A;  1UT4 A;  1QTS A;  3OYL A;  2D0A A;  2OFK A;  1P7M A;  1KO9 A;  4E7J A;  3C04 A;  1QNE A;  3KRM A;  1V5S A;  3L2R A;  4E9E A;  2G30 A;  4C7P A;  3F0Z A;  2QLV A;  1W80 A;  1NGN A;  3OYC A;  2JHN A;  1PU8 A;  2Y8L A;  3DPT A;  3EIK A;  3H1Z A;  3UW2 A; 
#chains in the Genus database with same CATH homology
 2XHI A;  3CVS A;  4E9F A;  1LWW A;  4EA5 A;  1WEF A;  1PU6 A;  5AN4 A;  1ORP A;  4B21 A;  1KG6 A;  1N39 A;  1LWV A;  3N0U A;  1VRL A;  1MUD A;  1MPG A;  4AIA A;  2ABK A;  1M3Q A;  4DK9 A;  1YQK A;  3F10 A;  4EJZ A;  1WEG A;  2JG6 A;  3CWU A;  1KG5 A;  3FHF A;  1WEI A;  2NOZ A;  2H56 A;  2YG9 A;  1MUN A;  3I0W A;  1XG7 A;  4OFA A;  1EBM A;  2NOF A;  3CVT A;  3IH7 A;  1M3H A;  1RRS A;  4UNF A;  5KN9 A;  5DPK A;  2I5W A;  1KG3 A;  4AI5 A;  1KG7 A;  1XQO A;  5CHZ A;  3OGD A;  4OFE A;  1P59 A;  1KEA A;  3KTU A;  5KN8 A;  2NOI A;  4EVV A;  2NOH A;  4YPH A;  4B23 A;  4UOB A;  3S6I A;  4EW0 A;  4EA4 A;  1DIZ A;  3KNT A;  2NOL A;  2OFI A;  3N5N X;  4OFH A;  2OFK A;  3IHO A;  1HU0 A;  1RRQ A;  1P7M A;  3CWS A;  3D4V A;  1KO9 A;  1FN7 A;  3CW7 A;  3CWT A;  1ORN A;  4AI4 A;  3OH9 A;  2NOB A;  1YQR A;  2JHJ A;  3G0Q A;  1LWY A;  1NKU A;  4YOQ A;  4YPR A;  3FHG A;  1LMZ A;  4E9H A;  4E9E A;  1N3A A;  4B24 A;  3F0Z A;  4EJY A;  1YQL A;  4E9G A;  1NGN A;  3I0X A;  2JHN A;  1PU7 A;  1N3C A;  3CWA A;  4HSB A;  3OH6 A;  1PVS A;  1XQP A;  4B22 A;  1PU8 A;  1KG2 A;  3FSP A;  4EW4 A;  1KG4 A;  2YG8 A;  2NOE A;  1MUY A;  4PII A;  1KQJ A;  1YQM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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