2JHJA

3-methyladenine dna-glycosylase from archaeoglobus fulgidus
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
295
structure length
290
Chain Sequence
MWRIELKHAVNWELKMKFFVLPELPTPDVVESGVWRRAIVLDGRAVAVMAYPESERTIVVEGNFENREWEAVRRKLVEYLGLQNPEELYRFMDGDEKLRMLKNRFYGFGRAGLMSMSVFEGIAKAIIQQQISFVVAEKLAAKIVGRFGDEVEWNGLKFYGFPTQEAILKAGVEGLRECGLSRRKAELIVEIAKEENLEELKEWGEEEAYEYLTSFKGIGRWTAELVLSMALGKNVFPADDLGVRRAVSRLYFNGEIQSAEKVREIARERFGRFARDILFYLFLYDRFFSV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Enzymatic Excision of N1-Methyladenine and N3-Methylcytosine from DNA
pubmed doi rcsb
molecule tags Hydrolase
source organism Archaeoglobus fulgidus
molecule keywords 3-METHYLADENINE DNA-GLYCOSYLASE
total genus 102
structure length 290
sequence length 295
chains with identical sequence B
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 2jhjA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 2jhjA03
3.30.310.20 Alpha Beta 2-Layer Sandwich TATA-Binding Protein DNA-3-methyladenine glycosylase AlkA, N-terminal domain 2jhjA01
3CWUA 2NOHA 5AN4A 3CWTA 1NKUA 1KG4A 1MPGA 5DPKA 3S6IA 1WEGA 1XG7A 1EBMA 3FHGA 1HU0A 1YQLA 2OFIA 1WEFA 4EW4A 1N39A 4OFEA 4EJZA 1M3HA 3FSPA 4B24A 1MUDA 4B21A 4EA5A 1M3QA 4E9GA 3CWAA 4EW0A 4DK9A 1KG7A 2YG8A 4AI4A 3OH9A 3CW7A 2NOFA 1P59A 3F10A 4UNFA 4HSBA 4OFAA 1KG6A 4B23A 1PVSA 1MUYA 1FN7A 1MUNA 2NOZA 2NOLA 1KG3A 1VRLA 3I0WA 3N5NX 3FHFA 1LWVA 1PU8A 3CVSA 2JG6A 1RRQA 5KN9A 4AI5A 5KN8A 1RRSA 4OFHA 1LMZA 1WEIA 3CWSA 1KQJA 1PU7A 4EVVA 1NGNA 4UOBA 2NOBA 3I0XA 3IH7A 1LWYA 4E9FA 1XQOA 4YOQA 4YPHA 3KNTA 1KG2A 2NOEA 1N3AA 1KEAA 2H56A 3F0ZA 2OFKA 2XHIA 1ORPA 4AIAA 4PIIA 3CVTA 3OGDA 1DIZA 5CHZA 3IHOA 3N0UA 1XQPA 4EA4A 1PU6A 1KO9A 3OH6A 1KG5A 1ORNA 2ABKA 4EJYA 1P7MA 4E9HA 2I5WA 1YQMA 1N3CA 4YPRA 1YQRA 2YG9A 4B22A 3G0QA 3KTUA 2JHNA 2JHJA 3D4VA 1LWWA 1YQKA 2NOIA 4E9EA
chains in the Genus database with same CATH superfamily
2R5XA 5AN4A 3CWTA 4EAKA 1MPGA 4BE2A 5FRMA 3RPJA 5BMPA 3OYEA 1VOKA 3S6IA 3ENCA 1HU0A 3OC3C 2FKMX 2OFIA 1KFIA 2NLVA 4OFEA 4EJZA 2JPSA 4BE0A 4HJHA 2H5AX 4B21A 4E9GA 2V75A 4EW0A 1W80A 1TGHA 3OH9A 3OYBA 1P59A 4BDYA 2V8QA 1QN4A 5JMVD 1MUYA 1J3MA 2MJ7A 1B9KA 2HKPA 4PY5A 2YA3A 4BDZA 1PU8A 2FUVA 2JG6A 3OYLA 2PWWA 4EVVA 2G30A 4ROEB 4UOBA 3NNQA 3IH7A 1LWYA 4NZGA 4YOQA 4YPHA 3KNTA 2FGTA 2H4LX 2F7LA 3TDHA 4BE1A 1K2YX 2H56A 4B0AA 4D7QA 3S3NA 2Y8LA 4AIAA 3OYJA 2DKCA 4PIIA 3CVTA 3PDKA 4IL8A 1PCJX 5CHZA 2VJ0A 1TBAB 4BJUA 1QNCA 1KYDA 3I3WA 5IYCP 5IYDP 3OSMA 4DULA 4Q11A 2ABKA 4CFFA 4YPRA 1YQRA 1RM1A 1PZDA 4B22A 2JPIA 3KTUA 2JHJA 2OOXA 1YQKA 2NOIA 3OYFA 2IV8A 2JOIA 2NOHA 1KFQA 3OS0A 3L2UA 1VTLE 1WEGA 1QNAA 1XG7A 1EBMA 3ULXA 1WEFA 3RSMA 1N39A 2DKAA 1M3HA 3TE5A 1MP9A 4B24A 1MUDA 4EA5A 1JDYA 3L2WA 4WX8A 1V5SA 2YG8A 1QN9A 1UT4A 2Z0FA 3R2XC 3OYNA 1PVSA 3L2VA 2NOLA 3ASMA 3OCIA 1VTOA 3SNSA 4C7PA 1UL7A 4IKFA 1LWVA 3L2QA 1NH2A 5KN9A 3OYMA 2EHBD 2NVMA 1LMZA 1KQJA 4E7KA 3OYCA 1PCZA 3I0XA 5EPCA 1JFIC 3N89A 1TBPA 3HS8A 5FROA 4E9FA 1XQOA 2NOEA 1N3AA 3OYKA 1QN6A 3OGDA 3OY9A 3S3OA 1R4XA 3L2RA 2OOYA 1KG5A 1QN7A 2QLVA 1P7MA 2I5WA 1YQMA 3LCNA 1WJWA 3G0QA 2W04A 4RODB 4E9EA 1U84A 1NKUA 1KG4A 5DPKA 2QRCA 1YQLA 4ZTFA 2Y8QA 4EW4A 1KYUA 2HZMA 4WZSD 5FRNA 4TPSA 4ROCB 4DK9A 3OYIA 2MZ8A 4EALA 5F9CA 4E7LA 1QTPA 4E7JA 5IYBP 4UNFA 1Q9UA 3OYGA 1KG6A 4B23A 1VOLB 2QRDA 1FN7A 1M5Q1 1MUNA 2NOZA 2HZSA 1KG3A 1NGMA 1VRLA 3VN5A 4I8OA 3N5NX 3FHFA 1EUVA 4WXAA 1WQAA 1VKLA 1T6AA 1RRSA 5JN5A 3CWSA 4E7IA 1PU7A 1TUOA 4BACA 1AISA 4D7RA 1KG2A 3OS2A 3HS9A 1QN3A 1KEAA 3VW4A 3OYDA 2O3OA 3F0ZA 2HL9A 3H1ZA 2OFKA 2YH5A 2DKDA 1DIZA 2D0AA 1LXTA 3IHOA 1KYFA 3N0UA 1XQPA 1PU6A 4EAJA 1KO9A 3OYAA 5BMNA 1QN5A 1QN8A 4EJYA 3OSTA 2HL8A 4ZTJA 3T4NA 2NWVA 1LWWA 3OS1A 3OYHA 1QNBA 3CWUA 3OLPA 2V9JA 2QR1A 1YTBA 3OSEA 1P5DX 3FHGA 3DPUA 1D3UA 2Z8UA 3BKQX 3FSPA 1QNEA 5HSHA 1YTFA 3S3MA 1C9BB 1M3QA 3EIKA 2ZFDB 3CWAA 1KG7A 4AI4A 1QTSA 3EAYA 3CW7A 1E42A 3C04A 1UT7A 2NOFA 3F10A 4HSBA 5KL0A 4OFAA 1K35A 2D0CA 4MRQA 3I0WA 4QG5A 1KY6A 3CVSA 1RRQA 4AI5A 2FKFA 5KN8A 2W03A 4OFHA 1WEIA 3KRMA 1NGNA 1CDWA 1P5GX 2NOBA 3DPTA 2IV9A 3PMGA 2D0BA 2QREA 2V92A 3NA5A 4EAGA 1KY7A 1C47A 4E7HA 2LAEA 2XHIA 1ORPA 1C4GA 3D7QA 3ENOC 4EA4A 3UW2A 1XSZA 3OH6A 1PCMX 1ORNA 4E9HA 4EAIA 1N3CA 2YG9A 2JHNA 3D4VA 1NVPA
chains in the Genus database with same CATH topology
3CWUA 2NOHA 5AN4A 3CWTA 1NKUA 1KG4A 1MPGA 5DPKA 3S6IA 1WEGA 1XG7A 1EBMA 3FHGA 1HU0A 1YQLA 2OFIA 1WEFA 4EW4A 1N39A 4OFEA 4EJZA 1M3HA 3FSPA 4B24A 1MUDA 4B21A 4EA5A 1M3QA 4E9GA 3CWAA 4EW0A 4DK9A 1KG7A 2YG8A 4AI4A 3OH9A 3CW7A 2NOFA 1P59A 3F10A 4UNFA 4HSBA 4OFAA 1KG6A 4B23A 1PVSA 1MUYA 1FN7A 1MUNA 2NOZA 2NOLA 1KG3A 1VRLA 3I0WA 3N5NX 3FHFA 1LWVA 1PU8A 3CVSA 2JG6A 1RRQA 5KN9A 4AI5A 5KN8A 1RRSA 4OFHA 1LMZA 1WEIA 3CWSA 1KQJA 1PU7A 4EVVA 1NGNA 4UOBA 2NOBA 3I0XA 3IH7A 1LWYA 4E9FA 1XQOA 4YOQA 4YPHA 3KNTA 1KG2A 2NOEA 1N3AA 1KEAA 2H56A 3F0ZA 2OFKA 2XHIA 1ORPA 4AIAA 4PIIA 3CVTA 3OGDA 1DIZA 5CHZA 3IHOA 3N0UA 1XQPA 4EA4A 1PU6A 1KO9A 3OH6A 1KG5A 1ORNA 2ABKA 4EJYA 1P7MA 4E9HA 2I5WA 1YQMA 1N3CA 4YPRA 1YQRA 2YG9A 4B22A 3G0QA 3KTUA 2JHNA 2JHJA 3D4VA 1LWWA 1YQKA 2NOIA 4E9EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CWU A;  2NOH A;  5AN4 A;  3CWT A;  1NKU A;  1KG4 A;  1MPG A;  5DPK A;  3S6I A;  1WEG A;  1XG7 A;  1EBM A;  3FHG A;  1HU0 A;  1YQL A;  2OFI A;  1WEF A;  4EW4 A;  1N39 A;  4OFE A;  4EJZ A;  1M3H A;  3FSP A;  4B24 A;  1MUD A;  4B21 A;  4EA5 A;  1M3Q A;  4E9G A;  3CWA A;  4EW0 A;  4DK9 A;  1KG7 A;  2YG8 A;  4AI4 A;  3OH9 A;  3CW7 A;  2NOF A;  1P59 A;  3F10 A;  4UNF A;  4HSB A;  4OFA A;  1KG6 A;  4B23 A;  1PVS A;  1MUY A;  1FN7 A;  1MUN A;  2NOZ A;  2NOL A;  1KG3 A;  1VRL A;  3I0W A;  3N5N X;  3FHF A;  1LWV A;  1PU8 A;  3CVS A;  2JG6 A;  1RRQ A;  5KN9 A;  4AI5 A;  5KN8 A;  1RRS A;  4OFH A;  1LMZ A;  1WEI A;  3CWS A;  1KQJ A;  1PU7 A;  4EVV A;  1NGN A;  4UOB A;  2NOB A;  3I0X A;  3IH7 A;  1LWY A;  4E9F A;  1XQO A;  4YOQ A;  4YPH A;  3KNT A;  1KG2 A;  2NOE A;  1N3A A;  1KEA A;  2H56 A;  3F0Z A;  2OFK A;  2XHI A;  1ORP A;  4AIA A;  4PII A;  3CVT A;  3OGD A;  1DIZ A;  5CHZ A;  3IHO A;  3N0U A;  1XQP A;  4EA4 A;  1PU6 A;  1KO9 A;  3OH6 A;  1KG5 A;  1ORN A;  2ABK A;  4EJY A;  1P7M A;  4E9H A;  2I5W A;  1YQM A;  1N3C A;  4YPR A;  1YQR A;  2YG9 A;  4B22 A;  3G0Q A;  3KTU A;  2JHN A;  2JHJ A;  3D4V A;  1LWW A;  1YQK A;  2NOI A;  4E9E A; 
#chains in the Genus database with same CATH topology
 2R5X A;  5AN4 A;  3CWT A;  4EAK A;  1MPG A;  4BE2 A;  5FRM A;  3RPJ A;  5BMP A;  3OYE A;  1VOK A;  3S6I A;  3ENC A;  1HU0 A;  3OC3 C;  2FKM X;  2OFI A;  1KFI A;  2NLV A;  4OFE A;  4EJZ A;  2JPS A;  4BE0 A;  4HJH A;  2H5A X;  4B21 A;  4E9G A;  2V75 A;  4EW0 A;  1W80 A;  1TGH A;  3OH9 A;  3OYB A;  1P59 A;  4BDY A;  2V8Q A;  1QN4 A;  5JMV D;  1MUY A;  1J3M A;  2MJ7 A;  1B9K A;  2HKP A;  4PY5 A;  2YA3 A;  4BDZ A;  1PU8 A;  2FUV A;  2JG6 A;  3OYL A;  2PWW A;  4EVV A;  2G30 A;  4ROE B;  4UOB A;  3NNQ A;  3IH7 A;  1LWY A;  4NZG A;  4YOQ A;  4YPH A;  3KNT A;  2FGT A;  2H4L X;  2F7L A;  3TDH A;  4BE1 A;  1K2Y X;  2H56 A;  4B0A A;  4D7Q A;  3S3N A;  2Y8L A;  4AIA A;  3OYJ A;  2DKC A;  4PII A;  3CVT A;  3PDK A;  4IL8 A;  1PCJ X;  5CHZ A;  2VJ0 A;  1TBA B;  4BJU A;  1QNC A;  1KYD A;  3I3W A;  5IYC P;  5IYD P;  3OSM A;  4DUL A;  4Q11 A;  2ABK A;  4CFF A;  4YPR A;  1YQR A;  1RM1 A;  1PZD A;  4B22 A;  2JPI A;  3KTU A;  2JHJ A;  2OOX A;  1YQK A;  2NOI A;  3OYF A;  2IV8 A;  2JOI A;  2NOH A;  1KFQ A;  3OS0 A;  3L2U A;  1VTL E;  1WEG A;  1QNA A;  1XG7 A;  1EBM A;  3ULX A;  1WEF A;  3RSM A;  1N39 A;  2DKA A;  1M3H A;  3TE5 A;  1MP9 A;  4B24 A;  1MUD A;  4EA5 A;  1JDY A;  3L2W A;  4WX8 A;  1V5S A;  2YG8 A;  1QN9 A;  1UT4 A;  2Z0F A;  3R2X C;  3OYN A;  1PVS A;  3L2V A;  2NOL A;  3ASM A;  3OCI A;  1VTO A;  3SNS A;  4C7P A;  1UL7 A;  4IKF A;  1LWV A;  3L2Q A;  1NH2 A;  5KN9 A;  3OYM A;  2EHB D;  2NVM A;  1LMZ A;  1KQJ A;  4E7K A;  3OYC A;  1PCZ A;  3I0X A;  5EPC A;  1JFI C;  3N89 A;  1TBP A;  3HS8 A;  5FRO A;  4E9F A;  1XQO A;  2NOE A;  1N3A A;  3OYK A;  1QN6 A;  3OGD A;  3OY9 A;  3S3O A;  1R4X A;  3L2R A;  2OOY A;  1KG5 A;  1QN7 A;  2QLV A;  1P7M A;  2I5W A;  1YQM A;  3LCN A;  1WJW A;  3G0Q A;  2W04 A;  4ROD B;  4E9E A;  1U84 A;  1NKU A;  1KG4 A;  5DPK A;  2QRC A;  1YQL A;  4ZTF A;  2Y8Q A;  4EW4 A;  1KYU A;  2HZM A;  4WZS D;  5FRN A;  4TPS A;  4ROC B;  4DK9 A;  3OYI A;  2MZ8 A;  4EAL A;  5F9C A;  4E7L A;  1QTP A;  4E7J A;  5IYB P;  4UNF A;  1Q9U A;  3OYG A;  1KG6 A;  4B23 A;  1VOL B;  2QRD A;  1FN7 A;  1M5Q 1;  1MUN A;  2NOZ A;  2HZS A;  1KG3 A;  1NGM A;  1VRL A;  3VN5 A;  4I8O A;  3N5N X;  3FHF A;  1EUV A;  4WXA A;  1WQA A;  1VKL A;  1T6A A;  1RRS A;  5JN5 A;  3CWS A;  4E7I A;  1PU7 A;  1TUO A;  4BAC A;  1AIS A;  4D7R A;  1KG2 A;  3OS2 A;  3HS9 A;  1QN3 A;  1KEA A;  3VW4 A;  3OYD A;  2O3O A;  3F0Z A;  2HL9 A;  3H1Z A;  2OFK A;  2YH5 A;  2DKD A;  1DIZ A;  2D0A A;  1LXT A;  3IHO A;  1KYF A;  3N0U A;  1XQP A;  1PU6 A;  4EAJ A;  1KO9 A;  3OYA A;  5BMN A;  1QN5 A;  1QN8 A;  4EJY A;  3OST A;  2HL8 A;  4ZTJ A;  3T4N A;  2NWV A;  1LWW A;  3OS1 A;  3OYH A;  1QNB A;  3CWU A;  3OLP A;  2V9J A;  2QR1 A;  1YTB A;  3OSE A;  1P5D X;  3FHG A;  3DPU A;  1D3U A;  2Z8U A;  3BKQ X;  3FSP A;  1QNE A;  5HSH A;  1YTF A;  3S3M A;  1C9B B;  1M3Q A;  3EIK A;  2ZFD B;  3CWA A;  1KG7 A;  4AI4 A;  1QTS A;  3EAY A;  3CW7 A;  1E42 A;  3C04 A;  1UT7 A;  2NOF A;  3F10 A;  4HSB A;  5KL0 A;  4OFA A;  1K35 A;  2D0C A;  4MRQ A;  3I0W A;  4QG5 A;  1KY6 A;  3CVS A;  1RRQ A;  4AI5 A;  2FKF A;  5KN8 A;  2W03 A;  4OFH A;  1WEI A;  3KRM A;  1NGN A;  1CDW A;  1P5G X;  2NOB A;  3DPT A;  2IV9 A;  3PMG A;  2D0B A;  2QRE A;  2V92 A;  3NA5 A;  4EAG A;  1KY7 A;  1C47 A;  4E7H A;  2LAE A;  2XHI A;  1ORP A;  1C4G A;  3D7Q A;  3ENO C;  4EA4 A;  3UW2 A;  1XSZ A;  3OH6 A;  1PCM X;  1ORN A;  4E9H A;  4EAI A;  1N3C A;  2YG9 A;  2JHN A;  3D4V A;  1NVP A; 
#chains in the Genus database with same CATH homology
 3CWU A;  2NOH A;  5AN4 A;  3CWT A;  1NKU A;  1KG4 A;  1MPG A;  5DPK A;  3S6I A;  1WEG A;  1XG7 A;  1EBM A;  3FHG A;  1HU0 A;  1YQL A;  2OFI A;  1WEF A;  4EW4 A;  1N39 A;  4OFE A;  4EJZ A;  1M3H A;  3FSP A;  4B24 A;  1MUD A;  4B21 A;  4EA5 A;  1M3Q A;  4E9G A;  3CWA A;  4EW0 A;  4DK9 A;  1KG7 A;  2YG8 A;  4AI4 A;  3OH9 A;  3CW7 A;  2NOF A;  1P59 A;  3F10 A;  4UNF A;  4HSB A;  4OFA A;  1KG6 A;  4B23 A;  1PVS A;  1MUY A;  1FN7 A;  1MUN A;  2NOZ A;  2NOL A;  1KG3 A;  1VRL A;  3I0W A;  3N5N X;  3FHF A;  1LWV A;  1PU8 A;  3CVS A;  2JG6 A;  1RRQ A;  5KN9 A;  4AI5 A;  5KN8 A;  1RRS A;  4OFH A;  1LMZ A;  1WEI A;  3CWS A;  1KQJ A;  1PU7 A;  4EVV A;  1NGN A;  4UOB A;  2NOB A;  3I0X A;  3IH7 A;  1LWY A;  4E9F A;  1XQO A;  4YOQ A;  4YPH A;  3KNT A;  1KG2 A;  2NOE A;  1N3A A;  1KEA A;  2H56 A;  3F0Z A;  2OFK A;  2XHI A;  1ORP A;  4AIA A;  4PII A;  3CVT A;  3OGD A;  1DIZ A;  5CHZ A;  3IHO A;  3N0U A;  1XQP A;  4EA4 A;  1PU6 A;  1KO9 A;  3OH6 A;  1KG5 A;  1ORN A;  2ABK A;  4EJY A;  1P7M A;  4E9H A;  2I5W A;  1YQM A;  1N3C A;  4YPR A;  1YQR A;  2YG9 A;  4B22 A;  3G0Q A;  3KTU A;  2JHN A;  2JHJ A;  3D4V A;  1LWW A;  1YQK A;  2NOI A;  4E9E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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