2JHNA

3-methyladenine dna-glycosylase from archaeoglobus fulgidus
Total Genus 103
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
295
structure length
293
Chain Sequence
MWRIELKHAVNWELKMKFFVLPELPTPDVVESGVWRRAIVLDGRAVAVMAYPESERTIVVEGNFENREWEAVRRKLVEYLGLQNPEELYRFMDGDEKLRMLKNRFYGFGRAGLMSMSVFEGIAKAIIQQQISFVVAEKLAAKIVGRFGDEVEWNGLKFYGFPTQEAILKAGVEGLRECGLSRRKAELIVEIAKEENLEELKEWGEEEAYEYLTSFKGIGRWTAELVLSIALGKNVFPADDLGVRRAVSRLYFNGEIQSAEKVREIARERFGRFARDILFYLFLYDRFFSKELV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural Basis for Enzymatic Excision of N1-Methyladenine and N3-Methylcytosine from DNA
pubmed doi rcsb
molecule tags Hydrolase
source organism Archaeoglobus fulgidus
molecule keywords 3-METHYLADENINE DNA-GLYCOSYLASE
total genus 103
structure length 293
sequence length 295
chains with identical sequence B
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 2jhnA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 2jhnA03
3.30.310.20 Alpha Beta 2-Layer Sandwich TATA-Binding Protein DNA-3-methyladenine glycosylase AlkA, N-terminal domain 2jhnA01
3IHOA 3CWUA 3G0QA 2NOZA 1RRQA 1LWVA 4OFAA 1YQLA 2NOBA 1KG2A 1WEIA 2YG9A 1WEFA 4EW0A 2XHIA 1NKUA 1XQOA 3OH6A 4PIIA 3KNTA 2I5WA 1ORPA 4EW4A 3FHGA 1N3CA 3OH9A 1EBMA 1MUYA 4B21A 1LWYA 3F0ZA 5CHZA 1HU0A 4EA5A 3CW7A 1WEGA 4B22A 1DIZA 4AIAA 4YPHA 2OFIA 1PU7A 1N39A 3CWSA 1VRLA 4B23A 3I0WA 1YQKA 2JG6A 3CVSA 3D4VA 1RRSA 1YQMA 1KG5A 1M3HA 3N5NX 2NOLA 4OFEA 5KN9A 2JHJA 1YQRA 3KTUA 4YOQA 3OGDA 1N3AA 2NOIA 3FHFA 1KQJA 2NOFA 5AN4A 2NOEA 4AI5A 4E9HA 3F10A 1FN7A 3CWTA 1XQPA 4UOBA 1PU8A 1M3QA 3FSPA 5DPKA 2YG8A 1P7MA 1KEAA 1KG3A 1XG7A 1KG4A 4EA4A 4OFHA 4EVVA 4E9GA 4HSBA 1P59A 4AI4A 4EJZA 1PVSA 2H56A 1KG7A 5KN8A 4E9FA 1KG6A 1MPGA 1MUDA 4UNFA 4B24A 1PU6A 2ABKA 3CWAA 1LWWA 2NOHA 1LMZA 3S6IA 3CVTA 2JHNA 1ORNA 4YPRA 2OFKA 3IH7A 4EJYA 3N0UA 1KO9A 1MUNA 4DK9A 3I0XA 1NGNA 4E9EA
chains in the Genus database with same CATH superfamily
2Z0FA 3IHOA 3CWUA 3OYDA 1RRQA 1B9KA 4BE1A 1WEIA 3KRMA 2QR1A 2D0BA 2XHIA 2VJ0A 3OCIA 4PIIA 4BE0A 2I5WA 1ORPA 1K2YX 3OS2A 3C04A 1TBPA 1QNBA 1QNCA 1LWYA 3F0ZA 1HU0A 3NA5A 4EA5A 1MP9A 3OSEA 3OYHA 2OOXA 2FUVA 1W80A 2YA3A 4AIAA 3OYIA 2NLVA 3VW4A 2OFIA 3EIKA 3OC3C 1WQAA 4BJUA 2JG6A 3CVSA 1RRSA 1YQMA 4WXAA 1M3HA 4RODB 5IYCP 2FKFA 4BE2A 5KN9A 2JHJA 1YQRA 2YH5A 1Q9UA 4YOQA 3OGDA 4QG5A 5KL0A 3ENOC 2NOFA 1NGMA 4EAGA 1XQPA 3N89A 3RSMA 3L2WA 1QNAA 3OYLA 3BKQX 4EA4A 4EVVA 3D7QA 2H4LX 3OYNA 1KFIA 1KYFA 5KN8A 4B24A 1ORNA 2PWWA 2NWVA 2QLVA 4DK9A 4DULA 1QN8A 4IKFA 3ASMA 5JMVD 3DPUA 1KY7A 1LWVA 3L2QA 1WEFA 2D0CA 5BMPA 3OYCA 1QN6A 3OYAA 3OH6A 1AISA 3FHGA 1YTFA 1VKLA 1EBMA 4ROCB 4B21A 3CW7A 1C4GA 3NNQA 4E7JA 4B22A 1RM1A 4CFFA 1TBAB 1N39A 1VRLA 4B23A 4E7IA 1YQKA 1D3UA 1PZDA 3HS9A 1P5GX 2EHBD 3TE5A 3OSMA 1UT7A 4EAJA 2LAEA 1UL7A 2IV8A 4OFEA 4BDYA 3KTUA 2HZMA 3FHFA 1NH2A 3S3MA 2HL8A 5AN4A 2V9JA 4TPSA 4E9HA 4BACA 3F10A 1NVPA 4UOBA 1PU8A 2W03A 1M3QA 1QN7A 2QRCA 3L2VA 1E42A 1K35A 1KEAA 1WJWA 2FKMX 1KG3A 1KG4A 1CDWA 1T6AA 2MJ7A 1P59A 4AI4A 2IV9A 1EUVA 1KG7A 3OY9A 1PCZA 4HJHA 1MUDA 3OYMA 4UNFA 5IYDP 1PU6A 3PMGA 1U84A 2JHNA 2OFKA 1PCJX 5FRNA 1XSZA 1KO9A 3OYGA 3G0QA 2HKPA 5EPCA 1KG2A 2YG9A 3DPTA 4C7PA 4ZTJA 1XQOA 2DKCA 4MRQA 1VTOA 4EW4A 2QRDA 1N3CA 1M5Q1 3PDKA 1MUYA 5CHZA 1P5DX 1WEGA 2FGTA 1JDYA 1PU7A 3I3WA 3S3OA 2QREA 1PCMX 4BDZA 1JFIC 1C47A 2H5AX 3R2XC 4EAIA 3N5NX 3OSTA 2NOLA 2Z8UA 1V5SA 1N3AA 3ENCA 2D0AA 3OYKA 2NVMA 3OS0A 2F7LA 5FRMA 3OYFA 4AI5A 2HL9A 4I8OA 3CWTA 1FN7A 3FSPA 1KY6A 1P7MA 1VTLE 3UW2A 3L2RA 3TDHA 2O3OA 3OYEA 3EAYA 4B0AA 4ZTFA 4E9FA 1QTPA 3LCNA 3RPJA 1YTBA 1QTSA 3ULXA 3H1ZA 4EJYA 1TGHA 1MUNA 3OLPA 1KFQA 3I0XA 1NGNA 4NZGA 4E9EA 1KYUA 5BMNA 2JOIA 2NOZA 4OFAA 1YQLA 2NOBA 4EW0A 1NKUA 2Y8LA 3KNTA 4E7HA 4Q11A 5F9CA 1QNEA 4PY5A 2V8QA 3OH9A 1UT4A 4EAKA 3HS8A 3VN5A 1DIZA 2DKDA 4YPHA 3CWSA 4IL8A 3T4NA 2JPSA 2DKAA 3I0WA 4E7KA 2W04A 3D4VA 2V92A 1QN5A 1C9BB 2HZSA 2ZFDB 4WX8A 4WZSD 1KG5A 4D7QA 1VOKA 1TUOA 3SNSA 1VOLB 2NOIA 1KQJA 2MZ8A 1QN9A 2R5XA 3OYBA 3S3NA 4ROEB 2NOEA 4E7LA 1LXTA 4D7RA 5DPKA 2YG8A 1KYDA 1XG7A 3OS1A 3OYJA 4OFHA 4E9GA 4HSBA 1QN3A 5FROA 4EJZA 5JN5A 4EALA 1PVSA 2H56A 1KG6A 2OOYA 1MPGA 1QN4A 2ABKA 3CWAA 1LWWA 2NOHA 1LMZA 3S6IA 3CVTA 2V75A 4YPRA 3L2UA 3IH7A 2G30A 2Y8QA 3N0UA 1R4XA 5IYBP 2JPIA 1J3MA 5HSHA
chains in the Genus database with same CATH topology
3IHOA 3CWUA 3G0QA 2NOZA 1RRQA 1LWVA 4OFAA 1YQLA 2NOBA 1KG2A 1WEIA 2YG9A 1WEFA 4EW0A 2XHIA 1NKUA 1XQOA 3OH6A 4PIIA 3KNTA 2I5WA 1ORPA 4EW4A 3FHGA 1N3CA 3OH9A 1EBMA 1MUYA 4B21A 1LWYA 3F0ZA 5CHZA 1HU0A 4EA5A 3CW7A 1WEGA 4B22A 1DIZA 4AIAA 4YPHA 2OFIA 1PU7A 1N39A 3CWSA 1VRLA 4B23A 3I0WA 1YQKA 2JG6A 3CVSA 3D4VA 1RRSA 1YQMA 1KG5A 1M3HA 3N5NX 2NOLA 4OFEA 5KN9A 2JHJA 1YQRA 3KTUA 4YOQA 3OGDA 1N3AA 2NOIA 3FHFA 1KQJA 2NOFA 5AN4A 2NOEA 4AI5A 4E9HA 3F10A 1FN7A 3CWTA 1XQPA 4UOBA 1PU8A 1M3QA 3FSPA 5DPKA 2YG8A 1P7MA 1KEAA 1KG3A 1XG7A 1KG4A 4EA4A 4OFHA 4EVVA 4E9GA 4HSBA 1P59A 4AI4A 4EJZA 1PVSA 2H56A 1KG7A 5KN8A 4E9FA 1KG6A 1MPGA 1MUDA 4UNFA 4B24A 1PU6A 2ABKA 3CWAA 1LWWA 2NOHA 1LMZA 3S6IA 3CVTA 2JHNA 1ORNA 4YPRA 2OFKA 3IH7A 4EJYA 3N0UA 1KO9A 1MUNA 4DK9A 3I0XA 1NGNA 4E9EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IHO A;  3CWU A;  3G0Q A;  2NOZ A;  1RRQ A;  1LWV A;  4OFA A;  1YQL A;  2NOB A;  1KG2 A;  1WEI A;  2YG9 A;  1WEF A;  4EW0 A;  2XHI A;  1NKU A;  1XQO A;  3OH6 A;  4PII A;  3KNT A;  2I5W A;  1ORP A;  4EW4 A;  3FHG A;  1N3C A;  3OH9 A;  1EBM A;  1MUY A;  4B21 A;  1LWY A;  3F0Z A;  5CHZ A;  1HU0 A;  4EA5 A;  3CW7 A;  1WEG A;  4B22 A;  1DIZ A;  4AIA A;  4YPH A;  2OFI A;  1PU7 A;  1N39 A;  3CWS A;  1VRL A;  4B23 A;  3I0W A;  1YQK A;  2JG6 A;  3CVS A;  3D4V A;  1RRS A;  1YQM A;  1KG5 A;  1M3H A;  3N5N X;  2NOL A;  4OFE A;  5KN9 A;  2JHJ A;  1YQR A;  3KTU A;  4YOQ A;  3OGD A;  1N3A A;  2NOI A;  3FHF A;  1KQJ A;  2NOF A;  5AN4 A;  2NOE A;  4AI5 A;  4E9H A;  3F10 A;  1FN7 A;  3CWT A;  1XQP A;  4UOB A;  1PU8 A;  1M3Q A;  3FSP A;  5DPK A;  2YG8 A;  1P7M A;  1KEA A;  1KG3 A;  1XG7 A;  1KG4 A;  4EA4 A;  4OFH A;  4EVV A;  4E9G A;  4HSB A;  1P59 A;  4AI4 A;  4EJZ A;  1PVS A;  2H56 A;  1KG7 A;  5KN8 A;  4E9F A;  1KG6 A;  1MPG A;  1MUD A;  4UNF A;  4B24 A;  1PU6 A;  2ABK A;  3CWA A;  1LWW A;  2NOH A;  1LMZ A;  3S6I A;  3CVT A;  2JHN A;  1ORN A;  4YPR A;  2OFK A;  3IH7 A;  4EJY A;  3N0U A;  1KO9 A;  1MUN A;  4DK9 A;  3I0X A;  1NGN A;  4E9E A; 
#chains in the Genus database with same CATH topology
 2Z0F A;  3IHO A;  3CWU A;  3OYD A;  1RRQ A;  1B9K A;  4BE1 A;  1WEI A;  3KRM A;  2QR1 A;  2D0B A;  2XHI A;  2VJ0 A;  3OCI A;  4PII A;  4BE0 A;  2I5W A;  1ORP A;  1K2Y X;  3OS2 A;  3C04 A;  1TBP A;  1QNB A;  1QNC A;  1LWY A;  3F0Z A;  1HU0 A;  3NA5 A;  4EA5 A;  1MP9 A;  3OSE A;  3OYH A;  2OOX A;  2FUV A;  1W80 A;  2YA3 A;  4AIA A;  3OYI A;  2NLV A;  3VW4 A;  2OFI A;  3EIK A;  3OC3 C;  1WQA A;  4BJU A;  2JG6 A;  3CVS A;  1RRS A;  1YQM A;  4WXA A;  1M3H A;  4ROD B;  5IYC P;  2FKF A;  4BE2 A;  5KN9 A;  2JHJ A;  1YQR A;  2YH5 A;  1Q9U A;  4YOQ A;  3OGD A;  4QG5 A;  5KL0 A;  3ENO C;  2NOF A;  1NGM A;  4EAG A;  1XQP A;  3N89 A;  3RSM A;  3L2W A;  1QNA A;  3OYL A;  3BKQ X;  4EA4 A;  4EVV A;  3D7Q A;  2H4L X;  3OYN A;  1KFI A;  1KYF A;  5KN8 A;  4B24 A;  1ORN A;  2PWW A;  2NWV A;  2QLV A;  4DK9 A;  4DUL A;  1QN8 A;  4IKF A;  3ASM A;  5JMV D;  3DPU A;  1KY7 A;  1LWV A;  3L2Q A;  1WEF A;  2D0C A;  5BMP A;  3OYC A;  1QN6 A;  3OYA A;  3OH6 A;  1AIS A;  3FHG A;  1YTF A;  1VKL A;  1EBM A;  4ROC B;  4B21 A;  3CW7 A;  1C4G A;  3NNQ A;  4E7J A;  4B22 A;  1RM1 A;  4CFF A;  1TBA B;  1N39 A;  1VRL A;  4B23 A;  4E7I A;  1YQK A;  1D3U A;  1PZD A;  3HS9 A;  1P5G X;  2EHB D;  3TE5 A;  3OSM A;  1UT7 A;  4EAJ A;  2LAE A;  1UL7 A;  2IV8 A;  4OFE A;  4BDY A;  3KTU A;  2HZM A;  3FHF A;  1NH2 A;  3S3M A;  2HL8 A;  5AN4 A;  2V9J A;  4TPS A;  4E9H A;  4BAC A;  3F10 A;  1NVP A;  4UOB A;  1PU8 A;  2W03 A;  1M3Q A;  1QN7 A;  2QRC A;  3L2V A;  1E42 A;  1K35 A;  1KEA A;  1WJW A;  2FKM X;  1KG3 A;  1KG4 A;  1CDW A;  1T6A A;  2MJ7 A;  1P59 A;  4AI4 A;  2IV9 A;  1EUV A;  1KG7 A;  3OY9 A;  1PCZ A;  4HJH A;  1MUD A;  3OYM A;  4UNF A;  5IYD P;  1PU6 A;  3PMG A;  1U84 A;  2JHN A;  2OFK A;  1PCJ X;  5FRN A;  1XSZ A;  1KO9 A;  3OYG A;  3G0Q A;  2HKP A;  5EPC A;  1KG2 A;  2YG9 A;  3DPT A;  4C7P A;  4ZTJ A;  1XQO A;  2DKC A;  4MRQ A;  1VTO A;  4EW4 A;  2QRD A;  1N3C A;  1M5Q 1;  3PDK A;  1MUY A;  5CHZ A;  1P5D X;  1WEG A;  2FGT A;  1JDY A;  1PU7 A;  3I3W A;  3S3O A;  2QRE A;  1PCM X;  4BDZ A;  1JFI C;  1C47 A;  2H5A X;  3R2X C;  4EAI A;  3N5N X;  3OST A;  2NOL A;  2Z8U A;  1V5S A;  1N3A A;  3ENC A;  2D0A A;  3OYK A;  2NVM A;  3OS0 A;  2F7L A;  5FRM A;  3OYF A;  4AI5 A;  2HL9 A;  4I8O A;  3CWT A;  1FN7 A;  3FSP A;  1KY6 A;  1P7M A;  1VTL E;  3UW2 A;  3L2R A;  3TDH A;  2O3O A;  3OYE A;  3EAY A;  4B0A A;  4ZTF A;  4E9F A;  1QTP A;  3LCN A;  3RPJ A;  1YTB A;  1QTS A;  3ULX A;  3H1Z A;  4EJY A;  1TGH A;  1MUN A;  3OLP A;  1KFQ A;  3I0X A;  1NGN A;  4NZG A;  4E9E A;  1KYU A;  5BMN A;  2JOI A;  2NOZ A;  4OFA A;  1YQL A;  2NOB A;  4EW0 A;  1NKU A;  2Y8L A;  3KNT A;  4E7H A;  4Q11 A;  5F9C A;  1QNE A;  4PY5 A;  2V8Q A;  3OH9 A;  1UT4 A;  4EAK A;  3HS8 A;  3VN5 A;  1DIZ A;  2DKD A;  4YPH A;  3CWS A;  4IL8 A;  3T4N A;  2JPS A;  2DKA A;  3I0W A;  4E7K A;  2W04 A;  3D4V A;  2V92 A;  1QN5 A;  1C9B B;  2HZS A;  2ZFD B;  4WX8 A;  4WZS D;  1KG5 A;  4D7Q A;  1VOK A;  1TUO A;  3SNS A;  1VOL B;  2NOI A;  1KQJ A;  2MZ8 A;  1QN9 A;  2R5X A;  3OYB A;  3S3N A;  4ROE B;  2NOE A;  4E7L A;  1LXT A;  4D7R A;  5DPK A;  2YG8 A;  1KYD A;  1XG7 A;  3OS1 A;  3OYJ A;  4OFH A;  4E9G A;  4HSB A;  1QN3 A;  5FRO A;  4EJZ A;  5JN5 A;  4EAL A;  1PVS A;  2H56 A;  1KG6 A;  2OOY A;  1MPG A;  1QN4 A;  2ABK A;  3CWA A;  1LWW A;  2NOH A;  1LMZ A;  3S6I A;  3CVT A;  2V75 A;  4YPR A;  3L2U A;  3IH7 A;  2G30 A;  2Y8Q A;  3N0U A;  1R4X A;  5IYB P;  2JPI A;  1J3M A;  5HSH A; 
#chains in the Genus database with same CATH homology
 3IHO A;  3CWU A;  3G0Q A;  2NOZ A;  1RRQ A;  1LWV A;  4OFA A;  1YQL A;  2NOB A;  1KG2 A;  1WEI A;  2YG9 A;  1WEF A;  4EW0 A;  2XHI A;  1NKU A;  1XQO A;  3OH6 A;  4PII A;  3KNT A;  2I5W A;  1ORP A;  4EW4 A;  3FHG A;  1N3C A;  3OH9 A;  1EBM A;  1MUY A;  4B21 A;  1LWY A;  3F0Z A;  5CHZ A;  1HU0 A;  4EA5 A;  3CW7 A;  1WEG A;  4B22 A;  1DIZ A;  4AIA A;  4YPH A;  2OFI A;  1PU7 A;  1N39 A;  3CWS A;  1VRL A;  4B23 A;  3I0W A;  1YQK A;  2JG6 A;  3CVS A;  3D4V A;  1RRS A;  1YQM A;  1KG5 A;  1M3H A;  3N5N X;  2NOL A;  4OFE A;  5KN9 A;  2JHJ A;  1YQR A;  3KTU A;  4YOQ A;  3OGD A;  1N3A A;  2NOI A;  3FHF A;  1KQJ A;  2NOF A;  5AN4 A;  2NOE A;  4AI5 A;  4E9H A;  3F10 A;  1FN7 A;  3CWT A;  1XQP A;  4UOB A;  1PU8 A;  1M3Q A;  3FSP A;  5DPK A;  2YG8 A;  1P7M A;  1KEA A;  1KG3 A;  1XG7 A;  1KG4 A;  4EA4 A;  4OFH A;  4EVV A;  4E9G A;  4HSB A;  1P59 A;  4AI4 A;  4EJZ A;  1PVS A;  2H56 A;  1KG7 A;  5KN8 A;  4E9F A;  1KG6 A;  1MPG A;  1MUD A;  4UNF A;  4B24 A;  1PU6 A;  2ABK A;  3CWA A;  1LWW A;  2NOH A;  1LMZ A;  3S6I A;  3CVT A;  2JHN A;  1ORN A;  4YPR A;  2OFK A;  3IH7 A;  4EJY A;  3N0U A;  1KO9 A;  1MUN A;  4DK9 A;  3I0X A;  1NGN A;  4E9E A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...