3CVSA

Crystal structure of an alka host/guest complex 8oxoguanine:adenine base pair
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
282
structure length
282
Chain Sequence
MYTLNWQPPYDWSWMLGFLAARAVSSVETVADSYYARSLAVGEYRGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGRLGAARPGLRLPGCVDAFEQGVRAILGQLVSVAMAAKLTARVAQLYGERLDDFPEYICFPTPQRLAAADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRWTANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEGWQPDEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Escherichia coli
molecule keywords DNA-3-methyladenine glycosylase 2
total genus 89
structure length 282
sequence length 282
chains with identical sequence B, C, D
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 2008-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF06029 AlkA_N AlkA N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 3cvsA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 3cvsA03
3.30.310.20 Alpha Beta 2-Layer Sandwich TATA-Binding Protein DNA-3-methyladenine glycosylase AlkA, N-terminal domain 3cvsA01
3D4VA 1EBMA 1MUDA 4AI5A 2OFIA 3CW7A 4PIIA 4EVVA 1PU7A 1P7MA 1RRQA 1KQJA 4B22A 1P59A 3CWTA 1XQPA 2OFKA 1KO9A 1KG6A 2YG8A 3IH7A 1YQMA 3KTUA 4UNFA 4HSBA 4YPRA 1NGNA 3FHGA 3OGDA 4B24A 1ORPA 4AIAA 2NOEA 2H56A 4B21A 2NOFA 1WEGA 3N5NX 1YQLA 1HU0A 1LWWA 2I5WA 3FHFA 1VRLA 4E9HA 5AN4A 4EA5A 2NOIA 1KG5A 3FSPA 3OH6A 4OFEA 4OFHA 4EJZA 2NOZA 2JHNA 1N3AA 4EW4A 1LMZA 4DK9A 1MUYA 4OFAA 4YPHA 4YOQA 3I0XA 1WEFA 4EJYA 2NOLA 5KN8A 3CVSA 1MUNA 4EA4A 1KG3A 1N39A 2NOBA 1YQRA 3I0WA 1ORNA 1KG4A 1XG7A 1M3QA 4AI4A 5DPKA 5CHZA 1MPGA 4E9FA 1FN7A 1RRSA 1YQKA 1KG2A 1M3HA 3F10A 3CVTA 2JG6A 1PU6A 3CWAA 5KN9A 1PU8A 1XQOA 3OH9A 4B23A 4E9GA 1KEAA 3F0ZA 3CWUA 3IHOA 4EW0A 2NOHA 1PVSA 3KNTA 3CWSA 2ABKA 3G0QA 1KG7A 2YG9A 1LWVA 3N0UA 2XHIA 1NKUA 4UOBA 1LWYA 1N3CA 1WEIA 3S6IA 4E9EA 2JHJA 1DIZA
chains in the Genus database with same CATH superfamily
2IV8A 2LAEA 2OFIA 1D3UA 4BE2A 4BE0A 1C9BB 1NVPA 3OYJA 2HL9A 1KQJA 2JPIA 2FKFA 2Z8UA 3KTUA 4HSBA 4QG5A 4ZTFA 3RPJA 4BDYA 4B24A 2QRCA 2W04A 2NOFA 2YA3A 1KFQA 3OLPA 1VOKA 3OYFA 1VRLA 4RODB 1P5GX 1KG5A 5IYCP 2JHNA 5EPCA 1LMZA 4DK9A 3I0XA 1K35A 4YOQA 4WX8A 4EJYA 2NOLA 4EA4A 4D7RA 2MJ7A 1KG4A 2DKCA 4CFFA 5CHZA 2DKDA 1YQKA 2MZ8A 1M3HA 4BDZA 1CDWA 4WZSD 3CWAA 4BACA 5IYBP 1PU8A 1XQOA 3OYMA 4PY5A 4E7LA 2D0BA 3OSEA 3CWUA 3VW4A 1PVSA 4Q11A 1Q9UA 1TBPA 3OS2A 2DKAA 1PCJX 5HSHA 5FRNA 3S6IA 3ENCA 4IL8A 4ZTJA 2HZMA 4EALA 4AI5A 3CW7A 1PU7A 4HJHA 2NWVA 1P59A 1XQPA 3IH7A 2YG8A 1YQMA 5KL0A 4UNFA 2Y8QA 4YPRA 1QTSA 3KRMA 1ORPA 3L2RA 3OCIA 2NOEA 2H56A 3OYEA 3D7QA 1UT4A 2JOIA 2H4LX 3N5NX 1YTFA 5FRMA 2I5WA 3FHFA 4E9HA 5AN4A 3ULXA 3ASMA 5BMPA 2NOZA 1N3AA 2QRDA 1MP9A 1VTLE 3S3NA 3EIKA 4EAKA 1MUNA 2YH5A 1QN3A 2V9JA 3PDKA 1YQRA 3I0WA 1M3QA 1QNBA 3OSMA 1KG2A 3TE5A 2JG6A 1PU6A 3OH9A 4BE1A 3VN5A 2HKPA 1J3MA 3H1ZA 2D0AA 3IHOA 4EW0A 2NOHA 1NH2A 3CWSA 2ABKA 4E7IA 2YG9A 1LWVA 3OYNA 3N0UA 1UT7A 2QLVA 4UOBA 1VKLA 4D7QA 2HL8A 1QNAA 2R5XA 1QN7A 3UW2A 1K2YX 3D4VA 4PIIA 4EVVA 1RRQA 1P7MA 4B22A 3CWTA 1WQAA 4E7HA 2OFKA 2W03A 1KG6A 3OYDA 1QN9A 1RM1A 1V5SA 1W80A 2V8QA 3OGDA 2O3OA 3SNSA 5F9CA 3OYLA 2D0CA 4E7KA 2FGTA 1WEGA 1YQLA 1M5Q1 3L2WA 3T4NA 1HU0A 3ENOC 2FKMX 4EA5A 2NOIA 3FSPA 3OH6A 4EJZA 1JFIC 1VOLB 1WEFA 1U84A 1NGMA 2QR1A 4TPSA 3OYKA 2Y8LA 1KG3A 2NOBA 3OYHA 2IV9A 3BKQX 1KY7A 1ORNA 3L2VA 5DPKA 4E9FA 1TBAB 1RRSA 2QREA 3CVTA 2EHBD 3EAYA 3S3OA 1P5DX 4DULA 4E9GA 5FROA 1KEAA 4ROCB 1R4XA 1E42A 1QN6A 1QNCA 2OOXA 3L2UA 3C04A 2JPSA 3G0QA 2F7LA 3S3MA 1NKUA 1N3CA 2OOYA 1WEIA 1JDYA 3DPUA 2VJ0A 4WXAA 1PCZA 2Z0FA 1DIZA 1EBMA 1TUOA 1MUDA 4EAJA 3OYBA 4E7JA 3OS0A 3LCNA 1KY6A 5JN5A 1UL7A 1KO9A 1AISA 2PWWA 3NA5A 1QN5A 3I3WA 1NGNA 3FHGA 3R2XC 3OYIA 4AIAA 1QN4A 1KYUA 4B21A 3OSTA 5BMNA 3OS1A 3OC3C 1C4GA 4B0AA 1T6AA 4I8OA 1B9KA 3DPTA 1LWWA 4EAGA 3TDHA 2NLVA 1QNEA 2V92A 3NNQA 2HZSA 4OFEA 4OFHA 4ROEB 5IYDP 4BJUA 4EW4A 4IKFA 1C47A 1MUYA 4OFAA 4YPHA 1PCMX 4EAIA 4NZGA 3N89A 2G30A 5KN8A 3CVSA 3OYAA 1XSZA 1N39A 3RSMA 1PZDA 1XG7A 3L2QA 1KYFA 3HS9A 4AI4A 1QN8A 1MPGA 1FN7A 1LXTA 2H5AX 3F10A 3HS8A 3OYCA 5KN9A 4B23A 3PMGA 2V75A 3F0ZA 2NVMA 3KNTA 1QTPA 1WJWA 5JMVD 1KG7A 4MRQA 2ZFDB 1TGHA 2XHIA 1EUVA 1YTBA 1KYDA 1LWYA 4C7PA 3OY9A 4E9EA 2FUVA 2JHJA 3OYGA 1VTOA 1KFIA
chains in the Genus database with same CATH topology
3D4VA 1EBMA 1MUDA 4AI5A 2OFIA 3CW7A 4PIIA 4EVVA 1PU7A 1P7MA 1RRQA 1KQJA 4B22A 1P59A 3CWTA 1XQPA 2OFKA 1KO9A 1KG6A 2YG8A 3IH7A 1YQMA 3KTUA 4UNFA 4HSBA 4YPRA 1NGNA 3FHGA 3OGDA 4B24A 1ORPA 4AIAA 2NOEA 2H56A 4B21A 2NOFA 1WEGA 3N5NX 1YQLA 1HU0A 1LWWA 2I5WA 3FHFA 1VRLA 4E9HA 5AN4A 4EA5A 2NOIA 1KG5A 3FSPA 3OH6A 4OFEA 4OFHA 4EJZA 2NOZA 2JHNA 1N3AA 4EW4A 1LMZA 4DK9A 1MUYA 4OFAA 4YPHA 4YOQA 3I0XA 1WEFA 4EJYA 2NOLA 5KN8A 3CVSA 1MUNA 4EA4A 1KG3A 1N39A 2NOBA 1YQRA 3I0WA 1ORNA 1KG4A 1XG7A 1M3QA 4AI4A 5DPKA 5CHZA 1MPGA 4E9FA 1FN7A 1RRSA 1YQKA 1KG2A 1M3HA 3F10A 3CVTA 2JG6A 1PU6A 3CWAA 5KN9A 1PU8A 1XQOA 3OH9A 4B23A 4E9GA 1KEAA 3F0ZA 3CWUA 3IHOA 4EW0A 2NOHA 1PVSA 3KNTA 3CWSA 2ABKA 3G0QA 1KG7A 2YG9A 1LWVA 3N0UA 2XHIA 1NKUA 4UOBA 1LWYA 1N3CA 1WEIA 3S6IA 4E9EA 2JHJA 1DIZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3D4V A;  1EBM A;  1MUD A;  4AI5 A;  2OFI A;  3CW7 A;  4PII A;  4EVV A;  1PU7 A;  1P7M A;  1RRQ A;  1KQJ A;  4B22 A;  1P59 A;  3CWT A;  1XQP A;  2OFK A;  1KO9 A;  1KG6 A;  2YG8 A;  3IH7 A;  1YQM A;  3KTU A;  4UNF A;  4HSB A;  4YPR A;  1NGN A;  3FHG A;  3OGD A;  4B24 A;  1ORP A;  4AIA A;  2NOE A;  2H56 A;  4B21 A;  2NOF A;  1WEG A;  3N5N X;  1YQL A;  1HU0 A;  1LWW A;  2I5W A;  3FHF A;  1VRL A;  4E9H A;  5AN4 A;  4EA5 A;  2NOI A;  1KG5 A;  3FSP A;  3OH6 A;  4OFE A;  4OFH A;  4EJZ A;  2NOZ A;  2JHN A;  1N3A A;  4EW4 A;  1LMZ A;  4DK9 A;  1MUY A;  4OFA A;  4YPH A;  4YOQ A;  3I0X A;  1WEF A;  4EJY A;  2NOL A;  5KN8 A;  3CVS A;  1MUN A;  4EA4 A;  1KG3 A;  1N39 A;  2NOB A;  1YQR A;  3I0W A;  1ORN A;  1KG4 A;  1XG7 A;  1M3Q A;  4AI4 A;  5DPK A;  5CHZ A;  1MPG A;  4E9F A;  1FN7 A;  1RRS A;  1YQK A;  1KG2 A;  1M3H A;  3F10 A;  3CVT A;  2JG6 A;  1PU6 A;  3CWA A;  5KN9 A;  1PU8 A;  1XQO A;  3OH9 A;  4B23 A;  4E9G A;  1KEA A;  3F0Z A;  3CWU A;  3IHO A;  4EW0 A;  2NOH A;  1PVS A;  3KNT A;  3CWS A;  2ABK A;  3G0Q A;  1KG7 A;  2YG9 A;  1LWV A;  3N0U A;  2XHI A;  1NKU A;  4UOB A;  1LWY A;  1N3C A;  1WEI A;  3S6I A;  4E9E A;  2JHJ A;  1DIZ A; 
#chains in the Genus database with same CATH topology
 2IV8 A;  2LAE A;  2OFI A;  1D3U A;  4BE2 A;  4BE0 A;  1C9B B;  1NVP A;  3OYJ A;  2HL9 A;  1KQJ A;  2JPI A;  2FKF A;  2Z8U A;  3KTU A;  4HSB A;  4QG5 A;  4ZTF A;  3RPJ A;  4BDY A;  4B24 A;  2QRC A;  2W04 A;  2NOF A;  2YA3 A;  1KFQ A;  3OLP A;  1VOK A;  3OYF A;  1VRL A;  4ROD B;  1P5G X;  1KG5 A;  5IYC P;  2JHN A;  5EPC A;  1LMZ A;  4DK9 A;  3I0X A;  1K35 A;  4YOQ A;  4WX8 A;  4EJY A;  2NOL A;  4EA4 A;  4D7R A;  2MJ7 A;  1KG4 A;  2DKC A;  4CFF A;  5CHZ A;  2DKD A;  1YQK A;  2MZ8 A;  1M3H A;  4BDZ A;  1CDW A;  4WZS D;  3CWA A;  4BAC A;  5IYB P;  1PU8 A;  1XQO A;  3OYM A;  4PY5 A;  4E7L A;  2D0B A;  3OSE A;  3CWU A;  3VW4 A;  1PVS A;  4Q11 A;  1Q9U A;  1TBP A;  3OS2 A;  2DKA A;  1PCJ X;  5HSH A;  5FRN A;  3S6I A;  3ENC A;  4IL8 A;  4ZTJ A;  2HZM A;  4EAL A;  4AI5 A;  3CW7 A;  1PU7 A;  4HJH A;  2NWV A;  1P59 A;  1XQP A;  3IH7 A;  2YG8 A;  1YQM A;  5KL0 A;  4UNF A;  2Y8Q A;  4YPR A;  1QTS A;  3KRM A;  1ORP A;  3L2R A;  3OCI A;  2NOE A;  2H56 A;  3OYE A;  3D7Q A;  1UT4 A;  2JOI A;  2H4L X;  3N5N X;  1YTF A;  5FRM A;  2I5W A;  3FHF A;  4E9H A;  5AN4 A;  3ULX A;  3ASM A;  5BMP A;  2NOZ A;  1N3A A;  2QRD A;  1MP9 A;  1VTL E;  3S3N A;  3EIK A;  4EAK A;  1MUN A;  2YH5 A;  1QN3 A;  2V9J A;  3PDK A;  1YQR A;  3I0W A;  1M3Q A;  1QNB A;  3OSM A;  1KG2 A;  3TE5 A;  2JG6 A;  1PU6 A;  3OH9 A;  4BE1 A;  3VN5 A;  2HKP A;  1J3M A;  3H1Z A;  2D0A A;  3IHO A;  4EW0 A;  2NOH A;  1NH2 A;  3CWS A;  2ABK A;  4E7I A;  2YG9 A;  1LWV A;  3OYN A;  3N0U A;  1UT7 A;  2QLV A;  4UOB A;  1VKL A;  4D7Q A;  2HL8 A;  1QNA A;  2R5X A;  1QN7 A;  3UW2 A;  1K2Y X;  3D4V A;  4PII A;  4EVV A;  1RRQ A;  1P7M A;  4B22 A;  3CWT A;  1WQA A;  4E7H A;  2OFK A;  2W03 A;  1KG6 A;  3OYD A;  1QN9 A;  1RM1 A;  1V5S A;  1W80 A;  2V8Q A;  3OGD A;  2O3O A;  3SNS A;  5F9C A;  3OYL A;  2D0C A;  4E7K A;  2FGT A;  1WEG A;  1YQL A;  1M5Q 1;  3L2W A;  3T4N A;  1HU0 A;  3ENO C;  2FKM X;  4EA5 A;  2NOI A;  3FSP A;  3OH6 A;  4EJZ A;  1JFI C;  1VOL B;  1WEF A;  1U84 A;  1NGM A;  2QR1 A;  4TPS A;  3OYK A;  2Y8L A;  1KG3 A;  2NOB A;  3OYH A;  2IV9 A;  3BKQ X;  1KY7 A;  1ORN A;  3L2V A;  5DPK A;  4E9F A;  1TBA B;  1RRS A;  2QRE A;  3CVT A;  2EHB D;  3EAY A;  3S3O A;  1P5D X;  4DUL A;  4E9G A;  5FRO A;  1KEA A;  4ROC B;  1R4X A;  1E42 A;  1QN6 A;  1QNC A;  2OOX A;  3L2U A;  3C04 A;  2JPS A;  3G0Q A;  2F7L A;  3S3M A;  1NKU A;  1N3C A;  2OOY A;  1WEI A;  1JDY A;  3DPU A;  2VJ0 A;  4WXA A;  1PCZ A;  2Z0F A;  1DIZ A;  1EBM A;  1TUO A;  1MUD A;  4EAJ A;  3OYB A;  4E7J A;  3OS0 A;  3LCN A;  1KY6 A;  5JN5 A;  1UL7 A;  1KO9 A;  1AIS A;  2PWW A;  3NA5 A;  1QN5 A;  3I3W A;  1NGN A;  3FHG A;  3R2X C;  3OYI A;  4AIA A;  1QN4 A;  1KYU A;  4B21 A;  3OST A;  5BMN A;  3OS1 A;  3OC3 C;  1C4G A;  4B0A A;  1T6A A;  4I8O A;  1B9K A;  3DPT A;  1LWW A;  4EAG A;  3TDH A;  2NLV A;  1QNE A;  2V92 A;  3NNQ A;  2HZS A;  4OFE A;  4OFH A;  4ROE B;  5IYD P;  4BJU A;  4EW4 A;  4IKF A;  1C47 A;  1MUY A;  4OFA A;  4YPH A;  1PCM X;  4EAI A;  4NZG A;  3N89 A;  2G30 A;  5KN8 A;  3CVS A;  3OYA A;  1XSZ A;  1N39 A;  3RSM A;  1PZD A;  1XG7 A;  3L2Q A;  1KYF A;  3HS9 A;  4AI4 A;  1QN8 A;  1MPG A;  1FN7 A;  1LXT A;  2H5A X;  3F10 A;  3HS8 A;  3OYC A;  5KN9 A;  4B23 A;  3PMG A;  2V75 A;  3F0Z A;  2NVM A;  3KNT A;  1QTP A;  1WJW A;  5JMV D;  1KG7 A;  4MRQ A;  2ZFD B;  1TGH A;  2XHI A;  1EUV A;  1YTB A;  1KYD A;  1LWY A;  4C7P A;  3OY9 A;  4E9E A;  2FUV A;  2JHJ A;  3OYG A;  1VTO A;  1KFI A; 
#chains in the Genus database with same CATH homology
 3D4V A;  1EBM A;  1MUD A;  4AI5 A;  2OFI A;  3CW7 A;  4PII A;  4EVV A;  1PU7 A;  1P7M A;  1RRQ A;  1KQJ A;  4B22 A;  1P59 A;  3CWT A;  1XQP A;  2OFK A;  1KO9 A;  1KG6 A;  2YG8 A;  3IH7 A;  1YQM A;  3KTU A;  4UNF A;  4HSB A;  4YPR A;  1NGN A;  3FHG A;  3OGD A;  4B24 A;  1ORP A;  4AIA A;  2NOE A;  2H56 A;  4B21 A;  2NOF A;  1WEG A;  3N5N X;  1YQL A;  1HU0 A;  1LWW A;  2I5W A;  3FHF A;  1VRL A;  4E9H A;  5AN4 A;  4EA5 A;  2NOI A;  1KG5 A;  3FSP A;  3OH6 A;  4OFE A;  4OFH A;  4EJZ A;  2NOZ A;  2JHN A;  1N3A A;  4EW4 A;  1LMZ A;  4DK9 A;  1MUY A;  4OFA A;  4YPH A;  4YOQ A;  3I0X A;  1WEF A;  4EJY A;  2NOL A;  5KN8 A;  3CVS A;  1MUN A;  4EA4 A;  1KG3 A;  1N39 A;  2NOB A;  1YQR A;  3I0W A;  1ORN A;  1KG4 A;  1XG7 A;  1M3Q A;  4AI4 A;  5DPK A;  5CHZ A;  1MPG A;  4E9F A;  1FN7 A;  1RRS A;  1YQK A;  1KG2 A;  1M3H A;  3F10 A;  3CVT A;  2JG6 A;  1PU6 A;  3CWA A;  5KN9 A;  1PU8 A;  1XQO A;  3OH9 A;  4B23 A;  4E9G A;  1KEA A;  3F0Z A;  3CWU A;  3IHO A;  4EW0 A;  2NOH A;  1PVS A;  3KNT A;  3CWS A;  2ABK A;  3G0Q A;  1KG7 A;  2YG9 A;  1LWV A;  3N0U A;  2XHI A;  1NKU A;  4UOB A;  1LWY A;  1N3C A;  1WEI A;  3S6I A;  4E9E A;  2JHJ A;  1DIZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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