3CVTA

Crystal structure of an alka host/guest complex 8oxoguanine:cytosine base pair
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
282
structure length
282
Chain Sequence
MYTLNWQPPYDWSWMLGFLAARAVSSVETVADSYYARSLAVGEYRGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGRLGAARPGLRLPGCVDAFEQGVRAILGQLVSVAMAAKLTARVAQLYGERLDDFPEYICFPTPQRLAAADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRWTANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEGWQPDEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Escherichia coli
molecule keywords DNA-3-methyladenine glycosylase 2
total genus 85
structure length 282
sequence length 282
chains with identical sequence B, C, D
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 2008-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF06029 AlkA_N AlkA N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 3cvtA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 3cvtA03
3.30.310.20 Alpha Beta 2-Layer Sandwich TATA-Binding Protein DNA-3-methyladenine glycosylase AlkA, N-terminal domain 3cvtA01
4YPRA 1YQLA 3CWSA 1KG4A 2NOIA 4HSBA 4E9HA 1KG5A 3OH9A 1RRQA 1WEIA 1N3AA 1MUDA 3KNTA 1KQJA 1VRLA 1ORNA 2I5WA 1YQKA 4OFAA 1WEGA 1WEFA 3FHGA 2JG6A 3I0XA 4UOBA 1MUNA 4AI5A 1LWYA 4E9EA 1M3QA 1MUYA 1N3CA 4PIIA 3OH6A 1YQMA 1RRSA 2JHJA 5DPKA 3S6IA 2NOHA 3F10A 3CW7A 4EJZA 4EW0A 1LMZA 1YQRA 4EA4A 1KG7A 3I0WA 2NOEA 4EA5A 3FSPA 1PU7A 1LWVA 3N5NX 4YOQA 4EVVA 1XQOA 3CWUA 4B22A 1NGNA 3KTUA 2XHIA 2YG8A 3CVSA 5KN9A 1PU8A 3CVTA 2ABKA 1ORPA 1N39A 1M3HA 1KO9A 3FHFA 2NOBA 1KEAA 3IHOA 4E9FA 1XG7A 3G0QA 2OFKA 3N0UA 4UNFA 3CWAA 1EBMA 1P7MA 2H56A 3F0ZA 3OGDA 2NOLA 4DK9A 4OFEA 1DIZA 5KN8A 4EJYA 1FN7A 2JHNA 3D4VA 3CWTA 2NOFA 4OFHA 3IH7A 4B21A 1LWWA 1NKUA 1MPGA 1KG6A 2YG9A 5CHZA 4B24A 4E9GA 2NOZA 1PVSA 4EW4A 1PU6A 1KG3A 5AN4A 1HU0A 1KG2A 4AIAA 4AI4A 1P59A 2OFIA 4B23A 4YPHA 1XQPA
chains in the Genus database with same CATH superfamily
1C4GA 4YPRA 4EAIA 2HL8A 3OH9A 1RRQA 1QNBA 5FRMA 2HL9A 3KNTA 3OYMA 2I5WA 1WQAA 1KFQA 3FHGA 3I0XA 3PMGA 1Q9UA 1QN5A 3OH6A 2DKDA 1LXTA 4QG5A 3OSTA 4WX8A 3OYHA 4RODB 1QTSA 3CW7A 4ZTJA 4EJZA 4EA4A 1C9BB 3I0WA 2OOXA 2NOEA 4EA5A 1KFIA 3OS0A 1UT7A 3N5NX 4YOQA 4BACA 2EHBD 1TGHA 2YA3A 4D7RA 1PU8A 5F9CA 1KO9A 1C47A 3FHFA 3R2XC 1KEAA 1U84A 2QRDA 1VTOA 3N0UA 3CWAA 3OS2A 1KYUA 1UT4A 2D0CA 2QRCA 1QNCA 2JOIA 2DKCA 2JPIA 4EJYA 2QR1A 1KY7A 3CWTA 2FGTA 3OYCA 4B21A 1LWWA 4E7IA 1TBPA 4BJUA 2YG9A 1MPGA 5CHZA 3OYFA 3OYJA 2PWWA 1P5GX 1PVSA 3EIKA 4EW4A 4EALA 1PU6A 5AN4A 3S3OA 1KG2A 4AIAA 4AI4A 2FKFA 4TPSA 1UL7A 2Y8QA 4WZSD 4B23A 1XQPA 5KL0A 1YQLA 2OOYA 1KG4A 4HSBA 1YTBA 1KG5A 1KY6A 5IYCP 1KQJA 1QN7A 2V8QA 2YH5A 1LWYA 3NA5A 4I8OA 1EUVA 2ZFDB 1M3QA 3OYEA 5JN5A 4PIIA 4D7QA 1E42A 3S6IA 1QTPA 3ENCA 2W04A 2FKMX 4EW0A 3UW2A 4BE0A 2MJ7A 1PU7A 2Z8UA 5BMNA 1K35A 3CWUA 4B22A 3OCIA 4DULA 2HKPA 3OYDA 2D0AA 1RM1A 3KTUA 1QN9A 4EAJA 3CVSA 3DPUA 5KN9A 2ABKA 5FROA 4ROEB 1M3HA 2NOBA 1QN6A 1J3MA 1QN3A 1QN8A 3OYAA 1K2YX 4IKFA 3BKQX 1XG7A 1QNAA 2QLVA 3G0QA 1M5Q1 4WXAA 4B0AA 3OY9A 3SNSA 4CFFA 4OFEA 1DIZA 3OYLA 1FN7A 2JHNA 3D4VA 2NOFA 5FRNA 3PDKA 1NKUA 1KG6A 1TUOA 2NWVA 2NOZA 2V75A 1PCMX 2H5AX 4EAKA 4C7PA 1KYDA 4ZTFA 3ULXA 2F7LA 3CWSA 3T4NA 1WJWA 1WEIA 3I3WA 1VRLA 1ORNA 3OLPA 1YQKA 4OFAA 1JFIC 4E7JA 3VW4A 1D3UA 2O3OA 1VTLE 4E9EA 1YQMA 1RRSA 2G30A 3OS1A 1QN4A 1YQRA 1VOLB 1KG7A 1NH2A 2MZ8A 3VN5A 1LWVA 1VOKA 4EVVA 1PCZA 1AISA 2HZSA 3OYKA 1XQOA 2NVMA 2XHIA 1KYFA 1P5DX 3DPTA 3CVTA 4BE1A 1NVPA 1ORPA 1MP9A 3ASMA 5HSHA 3S3MA 2HZMA 2D0BA 1PCJX 3IHOA 2IV8A 4E9FA 3H1ZA 1PZDA 2OFKA 4UNFA 1EBMA 3N89A 1P7MA 2H56A 2FUVA 3F0ZA 3OGDA 1XSZA 3L2WA 5KN8A 2W03A 4Q11A 5EPCA 3KRMA 4OFHA 3OYGA 4B24A 2JPSA 4E9GA 4E7LA 1W80A 4NZGA 3NNQA 1KG3A 3TDHA 1HU0A 4BDZA 1P59A 3HS8A 3OYBA 2OFIA 4ROCB 4YPHA 1QNEA 1JDYA 2LAEA 2NOIA 4E9HA 1NGMA 3OYIA 1N3AA 1MUDA 1B9KA 2QREA 1T6AA 1WEGA 1WEFA 2JG6A 4HJHA 4UOBA 1MUNA 4AI5A 1YTFA 1R4XA 4MRQA 1MUYA 1N3CA 2H4LX 3ENOC 2JHJA 5DPKA 3RPJA 2VJ0A 3S3NA 2NOHA 4BE2A 3F10A 1LMZA 5JMVD 1V5SA 3TE5A 3FSPA 1CDWA 3L2QA 5BMPA 1NGNA 5IYBP 3L2UA 3OYNA 2YG8A 3LCNA 2IV9A 3L2RA 1N39A 2Z0FA 3OC3C 2DKAA 3D7QA 4EAGA 3EAYA 4PY5A 2NOLA 4DK9A 4IL8A 2V9JA 5IYDP 1VKLA 2Y8LA 3RSMA 3IH7A 4E7KA 2NLVA 4E7HA 3L2VA 3C04A 2R5XA 2V92A 3OSMA 3OSEA 1TBAB 3HS9A 4BDYA
chains in the Genus database with same CATH topology
4YPRA 1YQLA 3CWSA 1KG4A 2NOIA 4HSBA 4E9HA 1KG5A 3OH9A 1RRQA 1WEIA 1N3AA 1MUDA 3KNTA 1KQJA 1VRLA 1ORNA 2I5WA 1YQKA 4OFAA 1WEGA 1WEFA 3FHGA 2JG6A 3I0XA 4UOBA 1MUNA 4AI5A 1LWYA 4E9EA 1M3QA 1MUYA 1N3CA 4PIIA 3OH6A 1YQMA 1RRSA 2JHJA 5DPKA 3S6IA 2NOHA 3F10A 3CW7A 4EJZA 4EW0A 1LMZA 1YQRA 4EA4A 1KG7A 3I0WA 2NOEA 4EA5A 3FSPA 1PU7A 1LWVA 3N5NX 4YOQA 4EVVA 1XQOA 3CWUA 4B22A 1NGNA 3KTUA 2XHIA 2YG8A 3CVSA 5KN9A 1PU8A 3CVTA 2ABKA 1ORPA 1N39A 1M3HA 1KO9A 3FHFA 2NOBA 1KEAA 3IHOA 4E9FA 1XG7A 3G0QA 2OFKA 3N0UA 4UNFA 3CWAA 1EBMA 1P7MA 2H56A 3F0ZA 3OGDA 2NOLA 4DK9A 4OFEA 1DIZA 5KN8A 4EJYA 1FN7A 2JHNA 3D4VA 3CWTA 2NOFA 4OFHA 3IH7A 4B21A 1LWWA 1NKUA 1MPGA 1KG6A 2YG9A 5CHZA 4B24A 4E9GA 2NOZA 1PVSA 4EW4A 1PU6A 1KG3A 5AN4A 1HU0A 1KG2A 4AIAA 4AI4A 1P59A 2OFIA 4B23A 4YPHA 1XQPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YPR A;  1YQL A;  3CWS A;  1KG4 A;  2NOI A;  4HSB A;  4E9H A;  1KG5 A;  3OH9 A;  1RRQ A;  1WEI A;  1N3A A;  1MUD A;  3KNT A;  1KQJ A;  1VRL A;  1ORN A;  2I5W A;  1YQK A;  4OFA A;  1WEG A;  1WEF A;  3FHG A;  2JG6 A;  3I0X A;  4UOB A;  1MUN A;  4AI5 A;  1LWY A;  4E9E A;  1M3Q A;  1MUY A;  1N3C A;  4PII A;  3OH6 A;  1YQM A;  1RRS A;  2JHJ A;  5DPK A;  3S6I A;  2NOH A;  3F10 A;  3CW7 A;  4EJZ A;  4EW0 A;  1LMZ A;  1YQR A;  4EA4 A;  1KG7 A;  3I0W A;  2NOE A;  4EA5 A;  3FSP A;  1PU7 A;  1LWV A;  3N5N X;  4YOQ A;  4EVV A;  1XQO A;  3CWU A;  4B22 A;  1NGN A;  3KTU A;  2XHI A;  2YG8 A;  3CVS A;  5KN9 A;  1PU8 A;  3CVT A;  2ABK A;  1ORP A;  1N39 A;  1M3H A;  1KO9 A;  3FHF A;  2NOB A;  1KEA A;  3IHO A;  4E9F A;  1XG7 A;  3G0Q A;  2OFK A;  3N0U A;  4UNF A;  3CWA A;  1EBM A;  1P7M A;  2H56 A;  3F0Z A;  3OGD A;  2NOL A;  4DK9 A;  4OFE A;  1DIZ A;  5KN8 A;  4EJY A;  1FN7 A;  2JHN A;  3D4V A;  3CWT A;  2NOF A;  4OFH A;  3IH7 A;  4B21 A;  1LWW A;  1NKU A;  1MPG A;  1KG6 A;  2YG9 A;  5CHZ A;  4B24 A;  4E9G A;  2NOZ A;  1PVS A;  4EW4 A;  1PU6 A;  1KG3 A;  5AN4 A;  1HU0 A;  1KG2 A;  4AIA A;  4AI4 A;  1P59 A;  2OFI A;  4B23 A;  4YPH A;  1XQP A; 
#chains in the Genus database with same CATH topology
 1C4G A;  4YPR A;  4EAI A;  2HL8 A;  3OH9 A;  1RRQ A;  1QNB A;  5FRM A;  2HL9 A;  3KNT A;  3OYM A;  2I5W A;  1WQA A;  1KFQ A;  3FHG A;  3I0X A;  3PMG A;  1Q9U A;  1QN5 A;  3OH6 A;  2DKD A;  1LXT A;  4QG5 A;  3OST A;  4WX8 A;  3OYH A;  4ROD B;  1QTS A;  3CW7 A;  4ZTJ A;  4EJZ A;  4EA4 A;  1C9B B;  3I0W A;  2OOX A;  2NOE A;  4EA5 A;  1KFI A;  3OS0 A;  1UT7 A;  3N5N X;  4YOQ A;  4BAC A;  2EHB D;  1TGH A;  2YA3 A;  4D7R A;  1PU8 A;  5F9C A;  1KO9 A;  1C47 A;  3FHF A;  3R2X C;  1KEA A;  1U84 A;  2QRD A;  1VTO A;  3N0U A;  3CWA A;  3OS2 A;  1KYU A;  1UT4 A;  2D0C A;  2QRC A;  1QNC A;  2JOI A;  2DKC A;  2JPI A;  4EJY A;  2QR1 A;  1KY7 A;  3CWT A;  2FGT A;  3OYC A;  4B21 A;  1LWW A;  4E7I A;  1TBP A;  4BJU A;  2YG9 A;  1MPG A;  5CHZ A;  3OYF A;  3OYJ A;  2PWW A;  1P5G X;  1PVS A;  3EIK A;  4EW4 A;  4EAL A;  1PU6 A;  5AN4 A;  3S3O A;  1KG2 A;  4AIA A;  4AI4 A;  2FKF A;  4TPS A;  1UL7 A;  2Y8Q A;  4WZS D;  4B23 A;  1XQP A;  5KL0 A;  1YQL A;  2OOY A;  1KG4 A;  4HSB A;  1YTB A;  1KG5 A;  1KY6 A;  5IYC P;  1KQJ A;  1QN7 A;  2V8Q A;  2YH5 A;  1LWY A;  3NA5 A;  4I8O A;  1EUV A;  2ZFD B;  1M3Q A;  3OYE A;  5JN5 A;  4PII A;  4D7Q A;  1E42 A;  3S6I A;  1QTP A;  3ENC A;  2W04 A;  2FKM X;  4EW0 A;  3UW2 A;  4BE0 A;  2MJ7 A;  1PU7 A;  2Z8U A;  5BMN A;  1K35 A;  3CWU A;  4B22 A;  3OCI A;  4DUL A;  2HKP A;  3OYD A;  2D0A A;  1RM1 A;  3KTU A;  1QN9 A;  4EAJ A;  3CVS A;  3DPU A;  5KN9 A;  2ABK A;  5FRO A;  4ROE B;  1M3H A;  2NOB A;  1QN6 A;  1J3M A;  1QN3 A;  1QN8 A;  3OYA A;  1K2Y X;  4IKF A;  3BKQ X;  1XG7 A;  1QNA A;  2QLV A;  3G0Q A;  1M5Q 1;  4WXA A;  4B0A A;  3OY9 A;  3SNS A;  4CFF A;  4OFE A;  1DIZ A;  3OYL A;  1FN7 A;  2JHN A;  3D4V A;  2NOF A;  5FRN A;  3PDK A;  1NKU A;  1KG6 A;  1TUO A;  2NWV A;  2NOZ A;  2V75 A;  1PCM X;  2H5A X;  4EAK A;  4C7P A;  1KYD A;  4ZTF A;  3ULX A;  2F7L A;  3CWS A;  3T4N A;  1WJW A;  1WEI A;  3I3W A;  1VRL A;  1ORN A;  3OLP A;  1YQK A;  4OFA A;  1JFI C;  4E7J A;  3VW4 A;  1D3U A;  2O3O A;  1VTL E;  4E9E A;  1YQM A;  1RRS A;  2G30 A;  3OS1 A;  1QN4 A;  1YQR A;  1VOL B;  1KG7 A;  1NH2 A;  2MZ8 A;  3VN5 A;  1LWV A;  1VOK A;  4EVV A;  1PCZ A;  1AIS A;  2HZS A;  3OYK A;  1XQO A;  2NVM A;  2XHI A;  1KYF A;  1P5D X;  3DPT A;  3CVT A;  4BE1 A;  1NVP A;  1ORP A;  1MP9 A;  3ASM A;  5HSH A;  3S3M A;  2HZM A;  2D0B A;  1PCJ X;  3IHO A;  2IV8 A;  4E9F A;  3H1Z A;  1PZD A;  2OFK A;  4UNF A;  1EBM A;  3N89 A;  1P7M A;  2H56 A;  2FUV A;  3F0Z A;  3OGD A;  1XSZ A;  3L2W A;  5KN8 A;  2W03 A;  4Q11 A;  5EPC A;  3KRM A;  4OFH A;  3OYG A;  4B24 A;  2JPS A;  4E9G A;  4E7L A;  1W80 A;  4NZG A;  3NNQ A;  1KG3 A;  3TDH A;  1HU0 A;  4BDZ A;  1P59 A;  3HS8 A;  3OYB A;  2OFI A;  4ROC B;  4YPH A;  1QNE A;  1JDY A;  2LAE A;  2NOI A;  4E9H A;  1NGM A;  3OYI A;  1N3A A;  1MUD A;  1B9K A;  2QRE A;  1T6A A;  1WEG A;  1WEF A;  2JG6 A;  4HJH A;  4UOB A;  1MUN A;  4AI5 A;  1YTF A;  1R4X A;  4MRQ A;  1MUY A;  1N3C A;  2H4L X;  3ENO C;  2JHJ A;  5DPK A;  3RPJ A;  2VJ0 A;  3S3N A;  2NOH A;  4BE2 A;  3F10 A;  1LMZ A;  5JMV D;  1V5S A;  3TE5 A;  3FSP A;  1CDW A;  3L2Q A;  5BMP A;  1NGN A;  5IYB P;  3L2U A;  3OYN A;  2YG8 A;  3LCN A;  2IV9 A;  3L2R A;  1N39 A;  2Z0F A;  3OC3 C;  2DKA A;  3D7Q A;  4EAG A;  3EAY A;  4PY5 A;  2NOL A;  4DK9 A;  4IL8 A;  2V9J A;  5IYD P;  1VKL A;  2Y8L A;  3RSM A;  3IH7 A;  4E7K A;  2NLV A;  4E7H A;  3L2V A;  3C04 A;  2R5X A;  2V92 A;  3OSM A;  3OSE A;  1TBA B;  3HS9 A;  4BDY A; 
#chains in the Genus database with same CATH homology
 4YPR A;  1YQL A;  3CWS A;  1KG4 A;  2NOI A;  4HSB A;  4E9H A;  1KG5 A;  3OH9 A;  1RRQ A;  1WEI A;  1N3A A;  1MUD A;  3KNT A;  1KQJ A;  1VRL A;  1ORN A;  2I5W A;  1YQK A;  4OFA A;  1WEG A;  1WEF A;  3FHG A;  2JG6 A;  3I0X A;  4UOB A;  1MUN A;  4AI5 A;  1LWY A;  4E9E A;  1M3Q A;  1MUY A;  1N3C A;  4PII A;  3OH6 A;  1YQM A;  1RRS A;  2JHJ A;  5DPK A;  3S6I A;  2NOH A;  3F10 A;  3CW7 A;  4EJZ A;  4EW0 A;  1LMZ A;  1YQR A;  4EA4 A;  1KG7 A;  3I0W A;  2NOE A;  4EA5 A;  3FSP A;  1PU7 A;  1LWV A;  3N5N X;  4YOQ A;  4EVV A;  1XQO A;  3CWU A;  4B22 A;  1NGN A;  3KTU A;  2XHI A;  2YG8 A;  3CVS A;  5KN9 A;  1PU8 A;  3CVT A;  2ABK A;  1ORP A;  1N39 A;  1M3H A;  1KO9 A;  3FHF A;  2NOB A;  1KEA A;  3IHO A;  4E9F A;  1XG7 A;  3G0Q A;  2OFK A;  3N0U A;  4UNF A;  3CWA A;  1EBM A;  1P7M A;  2H56 A;  3F0Z A;  3OGD A;  2NOL A;  4DK9 A;  4OFE A;  1DIZ A;  5KN8 A;  4EJY A;  1FN7 A;  2JHN A;  3D4V A;  3CWT A;  2NOF A;  4OFH A;  3IH7 A;  4B21 A;  1LWW A;  1NKU A;  1MPG A;  1KG6 A;  2YG9 A;  5CHZ A;  4B24 A;  4E9G A;  2NOZ A;  1PVS A;  4EW4 A;  1PU6 A;  1KG3 A;  5AN4 A;  1HU0 A;  1KG2 A;  4AIA A;  4AI4 A;  1P59 A;  2OFI A;  4B23 A;  4YPH A;  1XQP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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