3OH6A

Alka undamaged dna complex: interrogation of a c:g base pair
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
288
structure length
288
Chain Sequence
MADIGSEFYTLNWQPPYDWSWMLGFLAARAVSSVETVADSYYARSLAVGEYRGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGRLGAARPGLRLPGCVDAFEQGVRAILGQLVSVAMAAKLTARVAQLYGERLDDFPEYICFPTPQRLAAADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRWTANYFALRGWQAKDVFLPDDCLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEGWQPDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Escherichia coli AlkA in Complex with Undamaged DNA.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Escherichia coli
molecule keywords DNA-3-methyladenine glycosylase 2
total genus 87
structure length 288
sequence length 288
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 2010-08-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 3oh6A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 3oh6A03
3.30.310.20 Alpha Beta 2-Layer Sandwich TATA-Binding Protein DNA-3-methyladenine glycosylase AlkA, N-terminal domain 3oh6A01
1KG6A 5DPKA 3CWUA 3IH7A 1KG7A 4OFAA 3CW7A 3FSPA 3D4VA 2I5WA 2NOEA 3FHFA 3IHOA 1N3CA 3CWTA 3I0XA 1YQLA 4EW4A 4AI4A 1DIZA 1EBMA 1LWYA 1WEIA 1PVSA 4PIIA 1PU6A 1KG3A 4OFHA 1NKUA 2OFKA 2ABKA 4EJZA 1YQMA 3FHGA 2NOIA 1LMZA 4B24A 1XQOA 3G0QA 3CVTA 4DK9A 1KQJA 1HU0A 4UOBA 1ORPA 1ORNA 1FN7A 2NOFA 2H56A 4EJYA 1MUYA 2NOBA 1N3AA 1KG2A 4YPHA 5CHZA 4E9FA 1PU7A 4E9HA 3I0WA 1PU8A 4EA4A 4B22A 2JHNA 1WEFA 3CVSA 1VRLA 1NGNA 1KO9A 1LWVA 2NOHA 1XG7A 1YQKA 1P59A 4EVVA 5KN9A 3CWAA 2JG6A 1N39A 4E9EA 1MUNA 1YQRA 4OFEA 1M3QA 3OGDA 5AN4A 4E9GA 1M3HA 3S6IA 2NOLA 4AIAA 3KTUA 3KNTA 4B23A 3F0ZA 2XHIA 1KG5A 1MPGA 1P7MA 5KN8A 1LWWA 2JHJA 1RRSA 3N0UA 1RRQA 2YG8A 3F10A 3OH9A 1KEAA 3N5NX 4UNFA 2OFIA 4YPRA 2NOZA 1WEGA 1MUDA 1XQPA 4AI5A 4EA5A 3CWSA 1KG4A 4HSBA 4YOQA 2YG9A 3OH6A 4EW0A 4B21A
chains in the Genus database with same CATH superfamily
1KG6A 3NA5A 2F7LA 2D0AA 2I5WA 2Y8QA 1AISA 1YQLA 4DULA 4BDZA 4AI4A 4ZTFA 1LWYA 1WEIA 1PVSA 1KG3A 1C47A 2OFKA 2D0CA 1WQAA 4WXAA 1WJWA 4B0AA 4EAIA 3G0QA 2VJ0A 2MJ7A 1KQJA 4BACA 1KG2A 2DKCA 5IYCP 4CFFA 1YTFA 4E9FA 1PU7A 3OYLA 3OSEA 4BDYA 4E9HA 1E42A 1PU8A 1KYUA 3H1ZA 4EA4A 3OYHA 4IKFA 1C4GA 3CVSA 1VRLA 1NGNA 1KO9A 1K35A 1QN3A 1XG7A 1YQKA 3ULXA 4EVVA 1QN9A 5KN9A 1B9KA 1QTPA 2JPSA 3OYAA 4PY5A 3HS9A 3I3WA 1YQRA 2NVMA 3ASMA 5AN4A 4E9GA 4E7IA 3OSMA 1PZDA 1U84A 4B23A 3SNSA 5FRMA 1P7MA 4C7PA 3KRMA 4QG5A 5HSHA 3OYMA 1JFIC 5KL0A 4ZTJA 4UNFA 2MZ8A 4YPRA 1WEGA 4AI5A 4EA5A 1QNBA 1KG4A 2FKMX 3VN5A 4YOQA 4EW0A 1R4XA 1PCZA 2JOIA 3UW2A 4OFAA 3CW7A 1QTSA 4BJUA 3TE5A 3FSPA 1QN7A 3OY9A 2NOEA 2W04A 3FHFA 3IHOA 1EUVA 1TBPA 1UL7A 3EAYA 2QRDA 1QN5A 2V8QA 3PDKA 4WX8A 4OFHA 4MRQA 2ABKA 5IYDP 2PWWA 4EJZA 2HL9A 1QN8A 1QNAA 3BKQX 1TGHA 1XQOA 2EHBD 3ENOC 5EPCA 1VOLB 1ORPA 3L2VA 1MUYA 2NOBA 4I8OA 3OYJA 4BE0A 3OYBA 3OLPA 3VW4A 5F9CA 1WEFA 2HZSA 1J3MA 1LWVA 2H5AX 3CWAA 2JG6A 4E9EA 2OOXA 2D0BA 4EAGA 4E7KA 1VOKA 1KFQA 2NOLA 4D7QA 4E7JA 2V75A 2FGTA 4IL8A 2DKAA 1KG5A 2NLVA 1P5GX 5KN8A 2JHJA 5IYBP 2YG8A 2HKPA 3R2XC 3F10A 1KY7A 1KEAA 3N5NX 4D7RA 1C9BB 3OYEA 4E7LA 2OFIA 2QRCA 4ROEB 1XQPA 1W80A 3LCNA 1VTOA 1XSZA 3OH6A 2FUVA 4B21A 5DPKA 3CWUA 1KYFA 1KG7A 2H4LX 1RM1A 3C04A 4HJHA 1N3CA 3CWTA 3HS8A 3I0XA 3TDHA 3DPUA 1DIZA 2FKFA 1EBMA 1TBAB 2O3OA 4PIIA 3DPTA 3L2RA 1NGMA 1YQMA 3FHGA 3OS0A 5BMNA 4B24A 3CVTA 4DK9A 1HU0A 2NOFA 5FROA 1FN7A 2G30A 1VTLE 2H56A 3S3NA 4EJYA 1N3AA 1QNEA 1JDYA 4Q11A 4YPHA 1D3UA 3I0WA 3D7QA 4B22A 3RPJA 1NVPA 2QR1A 2Z0FA 5JMVD 2NOHA 1K2YX 3OYFA 2R5XA 1P59A 1M5Q1 1N39A 3OYKA 3OSTA 1PCMX 2IV8A 1MUNA 1P5DX 3RSMA 1M3QA 1M3HA 1T6AA 1QNCA 4AIAA 3KNTA 1UT4A 3S3MA 2HL8A 1KFIA 3F0ZA 2XHIA 4RODB 1KY6A 5JN5A 2JPIA 1RRQA 2Z8UA 1PCJX 3EIKA 3PMGA 1MUDA 3OYIA 4EAJA 3CWSA 4E7HA 4HSBA 2V9JA 2W03A 3OS1A 4EALA 3IH7A 1QN4A 3ENCA 3D4VA 4TPSA 2OOYA 4BE2A 2DKDA 1MP9A 1TUOA 4EW4A 1V5SA 4BE1A 1PU6A 3NNQA 1NKUA 3OC3C 5FRNA 2Y8LA 2NOIA 3OYDA 1LMZA 2NWVA 4UOBA 1ORNA 1NH2A 1YTBA 2V92A 5CHZA 2QREA 3OYCA 2YA3A 2YH5A 3T4NA 2JHNA 3OYNA 2ZFDB 1LXTA 4ROCB 4OFEA 3OYGA 3OGDA 3OCIA 1KYDA 3S6IA 3KTUA 2QLVA 3N89A 3L2UA 4WZSD 2HZMA 1MPGA 3L2WA 4EAKA 1LWWA 2IV9A 1RRSA 3N0UA 5BMPA 1UT7A 1QN6A 4NZGA 1Q9UA 3OH9A 3L2QA 2LAEA 2NOZA 1CDWA 1VKLA 3S3OA 2YG9A 3OS2A
chains in the Genus database with same CATH topology
1KG6A 5DPKA 3CWUA 3IH7A 1KG7A 4OFAA 3CW7A 3FSPA 3D4VA 2I5WA 2NOEA 3FHFA 3IHOA 1N3CA 3CWTA 3I0XA 1YQLA 4EW4A 4AI4A 1DIZA 1EBMA 1LWYA 1WEIA 1PVSA 4PIIA 1PU6A 1KG3A 4OFHA 1NKUA 2OFKA 2ABKA 4EJZA 1YQMA 3FHGA 2NOIA 1LMZA 4B24A 1XQOA 3G0QA 3CVTA 4DK9A 1KQJA 1HU0A 4UOBA 1ORPA 1ORNA 1FN7A 2NOFA 2H56A 4EJYA 1MUYA 2NOBA 1N3AA 1KG2A 4YPHA 5CHZA 4E9FA 1PU7A 4E9HA 3I0WA 1PU8A 4EA4A 4B22A 2JHNA 1WEFA 3CVSA 1VRLA 1NGNA 1KO9A 1LWVA 2NOHA 1XG7A 1YQKA 1P59A 4EVVA 5KN9A 3CWAA 2JG6A 1N39A 4E9EA 1MUNA 1YQRA 4OFEA 1M3QA 3OGDA 5AN4A 4E9GA 1M3HA 3S6IA 2NOLA 4AIAA 3KTUA 3KNTA 4B23A 3F0ZA 2XHIA 1KG5A 1MPGA 1P7MA 5KN8A 1LWWA 2JHJA 1RRSA 3N0UA 1RRQA 2YG8A 3F10A 3OH9A 1KEAA 3N5NX 4UNFA 2OFIA 4YPRA 2NOZA 1WEGA 1MUDA 1XQPA 4AI5A 4EA5A 3CWSA 1KG4A 4HSBA 4YOQA 2YG9A 3OH6A 4EW0A 4B21A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KG6 A;  5DPK A;  3CWU A;  3IH7 A;  1KG7 A;  4OFA A;  3CW7 A;  3FSP A;  3D4V A;  2I5W A;  2NOE A;  3FHF A;  3IHO A;  1N3C A;  3CWT A;  3I0X A;  1YQL A;  4EW4 A;  4AI4 A;  1DIZ A;  1EBM A;  1LWY A;  1WEI A;  1PVS A;  4PII A;  1PU6 A;  1KG3 A;  4OFH A;  1NKU A;  2OFK A;  2ABK A;  4EJZ A;  1YQM A;  3FHG A;  2NOI A;  1LMZ A;  4B24 A;  1XQO A;  3G0Q A;  3CVT A;  4DK9 A;  1KQJ A;  1HU0 A;  4UOB A;  1ORP A;  1ORN A;  1FN7 A;  2NOF A;  2H56 A;  4EJY A;  1MUY A;  2NOB A;  1N3A A;  1KG2 A;  4YPH A;  5CHZ A;  4E9F A;  1PU7 A;  4E9H A;  3I0W A;  1PU8 A;  4EA4 A;  4B22 A;  2JHN A;  1WEF A;  3CVS A;  1VRL A;  1NGN A;  1KO9 A;  1LWV A;  2NOH A;  1XG7 A;  1YQK A;  1P59 A;  4EVV A;  5KN9 A;  3CWA A;  2JG6 A;  1N39 A;  4E9E A;  1MUN A;  1YQR A;  4OFE A;  1M3Q A;  3OGD A;  5AN4 A;  4E9G A;  1M3H A;  3S6I A;  2NOL A;  4AIA A;  3KTU A;  3KNT A;  4B23 A;  3F0Z A;  2XHI A;  1KG5 A;  1MPG A;  1P7M A;  5KN8 A;  1LWW A;  2JHJ A;  1RRS A;  3N0U A;  1RRQ A;  2YG8 A;  3F10 A;  3OH9 A;  1KEA A;  3N5N X;  4UNF A;  2OFI A;  4YPR A;  2NOZ A;  1WEG A;  1MUD A;  1XQP A;  4AI5 A;  4EA5 A;  3CWS A;  1KG4 A;  4HSB A;  4YOQ A;  2YG9 A;  3OH6 A;  4EW0 A;  4B21 A; 
#chains in the Genus database with same CATH topology
 1KG6 A;  3NA5 A;  2F7L A;  2D0A A;  2I5W A;  2Y8Q A;  1AIS A;  1YQL A;  4DUL A;  4BDZ A;  4AI4 A;  4ZTF A;  1LWY A;  1WEI A;  1PVS A;  1KG3 A;  1C47 A;  2OFK A;  2D0C A;  1WQA A;  4WXA A;  1WJW A;  4B0A A;  4EAI A;  3G0Q A;  2VJ0 A;  2MJ7 A;  1KQJ A;  4BAC A;  1KG2 A;  2DKC A;  5IYC P;  4CFF A;  1YTF A;  4E9F A;  1PU7 A;  3OYL A;  3OSE A;  4BDY A;  4E9H A;  1E42 A;  1PU8 A;  1KYU A;  3H1Z A;  4EA4 A;  3OYH A;  4IKF A;  1C4G A;  3CVS A;  1VRL A;  1NGN A;  1KO9 A;  1K35 A;  1QN3 A;  1XG7 A;  1YQK A;  3ULX A;  4EVV A;  1QN9 A;  5KN9 A;  1B9K A;  1QTP A;  2JPS A;  3OYA A;  4PY5 A;  3HS9 A;  3I3W A;  1YQR A;  2NVM A;  3ASM A;  5AN4 A;  4E9G A;  4E7I A;  3OSM A;  1PZD A;  1U84 A;  4B23 A;  3SNS A;  5FRM A;  1P7M A;  4C7P A;  3KRM A;  4QG5 A;  5HSH A;  3OYM A;  1JFI C;  5KL0 A;  4ZTJ A;  4UNF A;  2MZ8 A;  4YPR A;  1WEG A;  4AI5 A;  4EA5 A;  1QNB A;  1KG4 A;  2FKM X;  3VN5 A;  4YOQ A;  4EW0 A;  1R4X A;  1PCZ A;  2JOI A;  3UW2 A;  4OFA A;  3CW7 A;  1QTS A;  4BJU A;  3TE5 A;  3FSP A;  1QN7 A;  3OY9 A;  2NOE A;  2W04 A;  3FHF A;  3IHO A;  1EUV A;  1TBP A;  1UL7 A;  3EAY A;  2QRD A;  1QN5 A;  2V8Q A;  3PDK A;  4WX8 A;  4OFH A;  4MRQ A;  2ABK A;  5IYD P;  2PWW A;  4EJZ A;  2HL9 A;  1QN8 A;  1QNA A;  3BKQ X;  1TGH A;  1XQO A;  2EHB D;  3ENO C;  5EPC A;  1VOL B;  1ORP A;  3L2V A;  1MUY A;  2NOB A;  4I8O A;  3OYJ A;  4BE0 A;  3OYB A;  3OLP A;  3VW4 A;  5F9C A;  1WEF A;  2HZS A;  1J3M A;  1LWV A;  2H5A X;  3CWA A;  2JG6 A;  4E9E A;  2OOX A;  2D0B A;  4EAG A;  4E7K A;  1VOK A;  1KFQ A;  2NOL A;  4D7Q A;  4E7J A;  2V75 A;  2FGT A;  4IL8 A;  2DKA A;  1KG5 A;  2NLV A;  1P5G X;  5KN8 A;  2JHJ A;  5IYB P;  2YG8 A;  2HKP A;  3R2X C;  3F10 A;  1KY7 A;  1KEA A;  3N5N X;  4D7R A;  1C9B B;  3OYE A;  4E7L A;  2OFI A;  2QRC A;  4ROE B;  1XQP A;  1W80 A;  3LCN A;  1VTO A;  1XSZ A;  3OH6 A;  2FUV A;  4B21 A;  5DPK A;  3CWU A;  1KYF A;  1KG7 A;  2H4L X;  1RM1 A;  3C04 A;  4HJH A;  1N3C A;  3CWT A;  3HS8 A;  3I0X A;  3TDH A;  3DPU A;  1DIZ A;  2FKF A;  1EBM A;  1TBA B;  2O3O A;  4PII A;  3DPT A;  3L2R A;  1NGM A;  1YQM A;  3FHG A;  3OS0 A;  5BMN A;  4B24 A;  3CVT A;  4DK9 A;  1HU0 A;  2NOF A;  5FRO A;  1FN7 A;  2G30 A;  1VTL E;  2H56 A;  3S3N A;  4EJY A;  1N3A A;  1QNE A;  1JDY A;  4Q11 A;  4YPH A;  1D3U A;  3I0W A;  3D7Q A;  4B22 A;  3RPJ A;  1NVP A;  2QR1 A;  2Z0F A;  5JMV D;  2NOH A;  1K2Y X;  3OYF A;  2R5X A;  1P59 A;  1M5Q 1;  1N39 A;  3OYK A;  3OST A;  1PCM X;  2IV8 A;  1MUN A;  1P5D X;  3RSM A;  1M3Q A;  1M3H A;  1T6A A;  1QNC A;  4AIA A;  3KNT A;  1UT4 A;  3S3M A;  2HL8 A;  1KFI A;  3F0Z A;  2XHI A;  4ROD B;  1KY6 A;  5JN5 A;  2JPI A;  1RRQ A;  2Z8U A;  1PCJ X;  3EIK A;  3PMG A;  1MUD A;  3OYI A;  4EAJ A;  3CWS A;  4E7H A;  4HSB A;  2V9J A;  2W03 A;  3OS1 A;  4EAL A;  3IH7 A;  1QN4 A;  3ENC A;  3D4V A;  4TPS A;  2OOY A;  4BE2 A;  2DKD A;  1MP9 A;  1TUO A;  4EW4 A;  1V5S A;  4BE1 A;  1PU6 A;  3NNQ A;  1NKU A;  3OC3 C;  5FRN A;  2Y8L A;  2NOI A;  3OYD A;  1LMZ A;  2NWV A;  4UOB A;  1ORN A;  1NH2 A;  1YTB A;  2V92 A;  5CHZ A;  2QRE A;  3OYC A;  2YA3 A;  2YH5 A;  3T4N A;  2JHN A;  3OYN A;  2ZFD B;  1LXT A;  4ROC B;  4OFE A;  3OYG A;  3OGD A;  3OCI A;  1KYD A;  3S6I A;  3KTU A;  2QLV A;  3N89 A;  3L2U A;  4WZS D;  2HZM A;  1MPG A;  3L2W A;  4EAK A;  1LWW A;  2IV9 A;  1RRS A;  3N0U A;  5BMP A;  1UT7 A;  1QN6 A;  4NZG A;  1Q9U A;  3OH9 A;  3L2Q A;  2LAE A;  2NOZ A;  1CDW A;  1VKL A;  3S3O A;  2YG9 A;  3OS2 A; 
#chains in the Genus database with same CATH homology
 1KG6 A;  5DPK A;  3CWU A;  3IH7 A;  1KG7 A;  4OFA A;  3CW7 A;  3FSP A;  3D4V A;  2I5W A;  2NOE A;  3FHF A;  3IHO A;  1N3C A;  3CWT A;  3I0X A;  1YQL A;  4EW4 A;  4AI4 A;  1DIZ A;  1EBM A;  1LWY A;  1WEI A;  1PVS A;  4PII A;  1PU6 A;  1KG3 A;  4OFH A;  1NKU A;  2OFK A;  2ABK A;  4EJZ A;  1YQM A;  3FHG A;  2NOI A;  1LMZ A;  4B24 A;  1XQO A;  3G0Q A;  3CVT A;  4DK9 A;  1KQJ A;  1HU0 A;  4UOB A;  1ORP A;  1ORN A;  1FN7 A;  2NOF A;  2H56 A;  4EJY A;  1MUY A;  2NOB A;  1N3A A;  1KG2 A;  4YPH A;  5CHZ A;  4E9F A;  1PU7 A;  4E9H A;  3I0W A;  1PU8 A;  4EA4 A;  4B22 A;  2JHN A;  1WEF A;  3CVS A;  1VRL A;  1NGN A;  1KO9 A;  1LWV A;  2NOH A;  1XG7 A;  1YQK A;  1P59 A;  4EVV A;  5KN9 A;  3CWA A;  2JG6 A;  1N39 A;  4E9E A;  1MUN A;  1YQR A;  4OFE A;  1M3Q A;  3OGD A;  5AN4 A;  4E9G A;  1M3H A;  3S6I A;  2NOL A;  4AIA A;  3KTU A;  3KNT A;  4B23 A;  3F0Z A;  2XHI A;  1KG5 A;  1MPG A;  1P7M A;  5KN8 A;  1LWW A;  2JHJ A;  1RRS A;  3N0U A;  1RRQ A;  2YG8 A;  3F10 A;  3OH9 A;  1KEA A;  3N5N X;  4UNF A;  2OFI A;  4YPR A;  2NOZ A;  1WEG A;  1MUD A;  1XQP A;  4AI5 A;  4EA5 A;  3CWS A;  1KG4 A;  4HSB A;  4YOQ A;  2YG9 A;  3OH6 A;  4EW0 A;  4B21 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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