3CW7A

Crystal structure of an alka host/guest complex 8oxoguanine:cytosine base pair
Total Genus 88
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
282
structure length
282
Chain Sequence
MYTLNWQPPYDWSWMLGFLAARAVSSVETVADSYYARSLAVGEYRGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGRLGAARPGLRLPGCVDAFEQGVRAILGQLVSVAMAAKLTARVAQLYGERLDDFPEYICFPTPQRLAAADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRWTANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEGWQPDEA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Escherichia coli
molecule keywords DNA-3-methyladenine glycosylase 2
total genus 88
structure length 282
sequence length 282
chains with identical sequence B, C, D
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 2008-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
A PF06029 AlkA_N AlkA N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 3cw7A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 3cw7A03
3.30.310.20 Alpha Beta 2-Layer Sandwich TATA-Binding Protein DNA-3-methyladenine glycosylase AlkA, N-terminal domain 3cw7A01
1DIZA 1N3CA 1XQOA 4PIIA 3OH6A 2H56A 1PU8A 1KG7A 4EA4A 4B24A 2I5WA 1KG3A 1M3QA 3I0WA 1P7MA 2OFKA 1KG6A 3OGDA 3CVTA 2NOBA 1MPGA 1VRLA 1NKUA 4HSBA 1LMZA 2NOEA 4YPRA 4E9GA 3FSPA 1RRSA 1PVSA 3CWAA 2NOFA 2JHJA 1LWWA 1RRQA 3CW7A 4AI5A 3CVSA 1FN7A 5KN9A 4EW4A 2OFIA 1EBMA 2JHNA 4B21A 4B23A 3F0ZA 1YQRA 4E9HA 3CWSA 5CHZA 3CWUA 4OFHA 2YG8A 1M3HA 3FHFA 5KN8A 2NOLA 4AI4A 3OH9A 4YPHA 1WEIA 1MUYA 3KNTA 2ABKA 4AIAA 4UNFA 1ORNA 1LWVA 3FHGA 1LWYA 1KQJA 3CWTA 1PU6A 4EJYA 2NOHA 1KEAA 2XHIA 4EA5A 5AN4A 1MUDA 1HU0A 1XQPA 1XG7A 3N5NX 1YQKA 3D4VA 4EW0A 2NOIA 4E9EA 4DK9A 3G0QA 3KTUA 1P59A 1KG4A 1ORPA 3N0UA 1YQMA 3IHOA 1WEGA 4YOQA 1N39A 2NOZA 4EVVA 1WEFA 1KO9A 2JG6A 3S6IA 3IH7A 1PU7A 4OFAA 4E9FA 3F10A 2YG9A 1KG2A 4OFEA 3I0XA 1NGNA 1MUNA 1KG5A 1N3AA 4UOBA 1YQLA 4B22A 5DPKA 4EJZA
chains in the Genus database with same CATH superfamily
1KYFA 1N3CA 4EAJA 4EA4A 2I5WA 1VKLA 1KG3A 4EAGA 1M3QA 1T6AA 5JMVD 3OYBA 3OGDA 2NOBA 2D0BA 3ULXA 1QN9A 1KFIA 2NOEA 1PVSA 3HS8A 3TE5A 3OSTA 2NOFA 4BACA 1LWWA 4AI5A 3CVSA 1PCMX 1TUOA 1EBMA 4BE2A 1VTLE 2H5AX 4OFHA 1M3HA 2NOLA 1VOKA 5FROA 1QN4A 4YPHA 3RPJA 1QN5A 2W04A 1LWVA 2FGTA 2NOHA 4E7LA 1HU0A 2V8QA 2H4LX 2NVMA 3TDHA 3N5NX 2NOIA 4E7IA 2PWWA 1P59A 4BJUA 1E42A 4EAKA 1U84A 1N39A 3D7QA 2NOZA 2DKAA 2FUVA 1KY7A 1K35A 1KO9A 3S6IA 2F7LA 2MZ8A 2OOYA 4ROEB 3OYEA 1KG2A 1NGNA 1MP9A 5DPKA 1DIZA 2JPSA 2Y8QA 1UT4A 3OH6A 2JOIA 4C7PA 5IYBP 2G30A 1P7MA 2O3OA 2OFKA 3OSMA 1KG6A 1VRLA 3C04A 1W80A 1B9KA 3L2QA 2QR1A 2HZMA 5BMPA 4ROCB 1M5Q1 3OYKA 3CWAA 1QTPA 5FRNA 1QN6A 3CW7A 2YH5A 1WQAA 4IL8A 4E7JA 1Q9UA 4B21A 1YQRA 3OYAA 4E7HA 3CWUA 2YG8A 5KN8A 3OH9A 4WX8A 1MUYA 3R2XC 1TBAB 1ORNA 1VTOA 1LWYA 1PCJX 1RM1A 3CWTA 4EJYA 3S3MA 1PZDA 4EA5A 5AN4A 3L2RA 3OYIA 3DPUA 1NGMA 3KRMA 2LAEA 1YTFA 4HJHA 1D3UA 1YQMA 3NA5A 1P5GX 3HS9A 1PCZA 4EVVA 3ENCA 1WEFA 2HZSA 1KFQA 2JG6A 3H1ZA 4BDYA 2YA3A 3IH7A 3OYLA 2HL8A 1PU7A 4OFAA 4RODB 4OFEA 3L2UA 2ZFDB 4EJZA 1C9BB 1XQOA 1NVPA 4PIIA 2R5XA 4PY5A 1QNBA 3OSEA 2V92A 2D0AA 2MJ7A 1TGHA 3VW4A 3OYMA 4ZTFA 2QRCA 3CVTA 1MPGA 1NKUA 2D0CA 5KL0A 4DULA 4HSBA 1LMZA 4YPRA 1C47A 4MRQA 3L2VA 3OYCA 1NH2A 2JHJA 3T4NA 3UW2A 1J3MA 1FN7A 3OYNA 3OC3C 5F9CA 4BE0A 4B0AA 2W03A 3CWSA 3OYJA 3FHFA 3NNQA 1EUVA 2NWVA 1WEIA 1K2YX 3KNTA 2ABKA 1JDYA 3OYHA 1UT7A 1AISA 3FHGA 1KQJA 3OY9A 3S3NA 1PU6A 5FRMA 4QG5A 1MUDA 1C4GA 4ZTJA 5EPCA 4EW0A 4CFFA 3G0QA 3KTUA 1CDWA 4YOQA 3OCIA 4Q11A 3BKQX 3L2WA 1WJWA 2EHBD 3ENOC 2HL9A 4BDZA 4BE1A 4WXAA 1QNEA 2QREA 4D7QA 1JFIC 2HKPA 3F10A 5JN5A 1MUNA 1KG5A 2Z8UA 1QN3A 3DPTA 1KY6A 2QRDA 1UL7A 3ASMA 2H56A 1PU8A 1KG7A 4B24A 1KYDA 5IYDP 4I8OA 4TPSA 3I0WA 3S3OA 1KYUA 2OOXA 3EAYA 1VOLB 5BMNA 1V5SA 5IYCP 1R4XA 1QNAA 4E9GA 3FSPA 1RRSA 1QN8A 2IV9A 3EIKA 3OS0A 1XSZA 1QTSA 1RRQA 4EAIA 5KN9A 4EW4A 3OYFA 2OFIA 1YTBA 2JHNA 4B23A 3F0ZA 4WZSD 2Y8LA 3OS1A 1TBPA 4E9HA 1QNCA 3OYGA 2DKCA 2Z0FA 5CHZA 3PMGA 3N89A 3LCNA 4D7RA 2V9JA 3OYDA 4AI4A 5HSHA 4IKFA 2V75A 4AIAA 4UNFA 3RSMA 1P5DX 2IV8A 3SNSA 1KEAA 2XHIA 3OS2A 2NLVA 1XQPA 1XG7A 3OLPA 1YQKA 3D4VA 2FKFA 4E9EA 4EALA 4DK9A 2JPIA 3VN5A 1KG4A 1ORPA 3N0UA 3IHOA 1QN7A 1WEGA 3PDKA 2VJ0A 4NZGA 2QLVA 3I3WA 1LXTA 4E9FA 2YG9A 3I0XA 1N3AA 4UOBA 2FKMX 1YQLA 4B22A 4E7KA 2DKDA
chains in the Genus database with same CATH topology
1DIZA 1N3CA 1XQOA 4PIIA 3OH6A 2H56A 1PU8A 1KG7A 4EA4A 4B24A 2I5WA 1KG3A 1M3QA 3I0WA 1P7MA 2OFKA 1KG6A 3OGDA 3CVTA 2NOBA 1MPGA 1VRLA 1NKUA 4HSBA 1LMZA 2NOEA 4YPRA 4E9GA 3FSPA 1RRSA 1PVSA 3CWAA 2NOFA 2JHJA 1LWWA 1RRQA 3CW7A 4AI5A 3CVSA 1FN7A 5KN9A 4EW4A 2OFIA 1EBMA 2JHNA 4B21A 4B23A 3F0ZA 1YQRA 4E9HA 3CWSA 5CHZA 3CWUA 4OFHA 2YG8A 1M3HA 3FHFA 5KN8A 2NOLA 4AI4A 3OH9A 4YPHA 1WEIA 1MUYA 3KNTA 2ABKA 4AIAA 4UNFA 1ORNA 1LWVA 3FHGA 1LWYA 1KQJA 3CWTA 1PU6A 4EJYA 2NOHA 1KEAA 2XHIA 4EA5A 5AN4A 1MUDA 1HU0A 1XQPA 1XG7A 3N5NX 1YQKA 3D4VA 4EW0A 2NOIA 4E9EA 4DK9A 3G0QA 3KTUA 1P59A 1KG4A 1ORPA 3N0UA 1YQMA 3IHOA 1WEGA 4YOQA 1N39A 2NOZA 4EVVA 1WEFA 1KO9A 2JG6A 3S6IA 3IH7A 1PU7A 4OFAA 4E9FA 3F10A 2YG9A 1KG2A 4OFEA 3I0XA 1NGNA 1MUNA 1KG5A 1N3AA 4UOBA 1YQLA 4B22A 5DPKA 4EJZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DIZ A;  1N3C A;  1XQO A;  4PII A;  3OH6 A;  2H56 A;  1PU8 A;  1KG7 A;  4EA4 A;  4B24 A;  2I5W A;  1KG3 A;  1M3Q A;  3I0W A;  1P7M A;  2OFK A;  1KG6 A;  3OGD A;  3CVT A;  2NOB A;  1MPG A;  1VRL A;  1NKU A;  4HSB A;  1LMZ A;  2NOE A;  4YPR A;  4E9G A;  3FSP A;  1RRS A;  1PVS A;  3CWA A;  2NOF A;  2JHJ A;  1LWW A;  1RRQ A;  3CW7 A;  4AI5 A;  3CVS A;  1FN7 A;  5KN9 A;  4EW4 A;  2OFI A;  1EBM A;  2JHN A;  4B21 A;  4B23 A;  3F0Z A;  1YQR A;  4E9H A;  3CWS A;  5CHZ A;  3CWU A;  4OFH A;  2YG8 A;  1M3H A;  3FHF A;  5KN8 A;  2NOL A;  4AI4 A;  3OH9 A;  4YPH A;  1WEI A;  1MUY A;  3KNT A;  2ABK A;  4AIA A;  4UNF A;  1ORN A;  1LWV A;  3FHG A;  1LWY A;  1KQJ A;  3CWT A;  1PU6 A;  4EJY A;  2NOH A;  1KEA A;  2XHI A;  4EA5 A;  5AN4 A;  1MUD A;  1HU0 A;  1XQP A;  1XG7 A;  3N5N X;  1YQK A;  3D4V A;  4EW0 A;  2NOI A;  4E9E A;  4DK9 A;  3G0Q A;  3KTU A;  1P59 A;  1KG4 A;  1ORP A;  3N0U A;  1YQM A;  3IHO A;  1WEG A;  4YOQ A;  1N39 A;  2NOZ A;  4EVV A;  1WEF A;  1KO9 A;  2JG6 A;  3S6I A;  3IH7 A;  1PU7 A;  4OFA A;  4E9F A;  3F10 A;  2YG9 A;  1KG2 A;  4OFE A;  3I0X A;  1NGN A;  1MUN A;  1KG5 A;  1N3A A;  4UOB A;  1YQL A;  4B22 A;  5DPK A;  4EJZ A; 
#chains in the Genus database with same CATH topology
 1KYF A;  1N3C A;  4EAJ A;  4EA4 A;  2I5W A;  1VKL A;  1KG3 A;  4EAG A;  1M3Q A;  1T6A A;  5JMV D;  3OYB A;  3OGD A;  2NOB A;  2D0B A;  3ULX A;  1QN9 A;  1KFI A;  2NOE A;  1PVS A;  3HS8 A;  3TE5 A;  3OST A;  2NOF A;  4BAC A;  1LWW A;  4AI5 A;  3CVS A;  1PCM X;  1TUO A;  1EBM A;  4BE2 A;  1VTL E;  2H5A X;  4OFH A;  1M3H A;  2NOL A;  1VOK A;  5FRO A;  1QN4 A;  4YPH A;  3RPJ A;  1QN5 A;  2W04 A;  1LWV A;  2FGT A;  2NOH A;  4E7L A;  1HU0 A;  2V8Q A;  2H4L X;  2NVM A;  3TDH A;  3N5N X;  2NOI A;  4E7I A;  2PWW A;  1P59 A;  4BJU A;  1E42 A;  4EAK A;  1U84 A;  1N39 A;  3D7Q A;  2NOZ A;  2DKA A;  2FUV A;  1KY7 A;  1K35 A;  1KO9 A;  3S6I A;  2F7L A;  2MZ8 A;  2OOY A;  4ROE B;  3OYE A;  1KG2 A;  1NGN A;  1MP9 A;  5DPK A;  1DIZ A;  2JPS A;  2Y8Q A;  1UT4 A;  3OH6 A;  2JOI A;  4C7P A;  5IYB P;  2G30 A;  1P7M A;  2O3O A;  2OFK A;  3OSM A;  1KG6 A;  1VRL A;  3C04 A;  1W80 A;  1B9K A;  3L2Q A;  2QR1 A;  2HZM A;  5BMP A;  4ROC B;  1M5Q 1;  3OYK A;  3CWA A;  1QTP A;  5FRN A;  1QN6 A;  3CW7 A;  2YH5 A;  1WQA A;  4IL8 A;  4E7J A;  1Q9U A;  4B21 A;  1YQR A;  3OYA A;  4E7H A;  3CWU A;  2YG8 A;  5KN8 A;  3OH9 A;  4WX8 A;  1MUY A;  3R2X C;  1TBA B;  1ORN A;  1VTO A;  1LWY A;  1PCJ X;  1RM1 A;  3CWT A;  4EJY A;  3S3M A;  1PZD A;  4EA5 A;  5AN4 A;  3L2R A;  3OYI A;  3DPU A;  1NGM A;  3KRM A;  2LAE A;  1YTF A;  4HJH A;  1D3U A;  1YQM A;  3NA5 A;  1P5G X;  3HS9 A;  1PCZ A;  4EVV A;  3ENC A;  1WEF A;  2HZS A;  1KFQ A;  2JG6 A;  3H1Z A;  4BDY A;  2YA3 A;  3IH7 A;  3OYL A;  2HL8 A;  1PU7 A;  4OFA A;  4ROD B;  4OFE A;  3L2U A;  2ZFD B;  4EJZ A;  1C9B B;  1XQO A;  1NVP A;  4PII A;  2R5X A;  4PY5 A;  1QNB A;  3OSE A;  2V92 A;  2D0A A;  2MJ7 A;  1TGH A;  3VW4 A;  3OYM A;  4ZTF A;  2QRC A;  3CVT A;  1MPG A;  1NKU A;  2D0C A;  5KL0 A;  4DUL A;  4HSB A;  1LMZ A;  4YPR A;  1C47 A;  4MRQ A;  3L2V A;  3OYC A;  1NH2 A;  2JHJ A;  3T4N A;  3UW2 A;  1J3M A;  1FN7 A;  3OYN A;  3OC3 C;  5F9C A;  4BE0 A;  4B0A A;  2W03 A;  3CWS A;  3OYJ A;  3FHF A;  3NNQ A;  1EUV A;  2NWV A;  1WEI A;  1K2Y X;  3KNT A;  2ABK A;  1JDY A;  3OYH A;  1UT7 A;  1AIS A;  3FHG A;  1KQJ A;  3OY9 A;  3S3N A;  1PU6 A;  5FRM A;  4QG5 A;  1MUD A;  1C4G A;  4ZTJ A;  5EPC A;  4EW0 A;  4CFF A;  3G0Q A;  3KTU A;  1CDW A;  4YOQ A;  3OCI A;  4Q11 A;  3BKQ X;  3L2W A;  1WJW A;  2EHB D;  3ENO C;  2HL9 A;  4BDZ A;  4BE1 A;  4WXA A;  1QNE A;  2QRE A;  4D7Q A;  1JFI C;  2HKP A;  3F10 A;  5JN5 A;  1MUN A;  1KG5 A;  2Z8U A;  1QN3 A;  3DPT A;  1KY6 A;  2QRD A;  1UL7 A;  3ASM A;  2H56 A;  1PU8 A;  1KG7 A;  4B24 A;  1KYD A;  5IYD P;  4I8O A;  4TPS A;  3I0W A;  3S3O A;  1KYU A;  2OOX A;  3EAY A;  1VOL B;  5BMN A;  1V5S A;  5IYC P;  1R4X A;  1QNA A;  4E9G A;  3FSP A;  1RRS A;  1QN8 A;  2IV9 A;  3EIK A;  3OS0 A;  1XSZ A;  1QTS A;  1RRQ A;  4EAI A;  5KN9 A;  4EW4 A;  3OYF A;  2OFI A;  1YTB A;  2JHN A;  4B23 A;  3F0Z A;  4WZS D;  2Y8L A;  3OS1 A;  1TBP A;  4E9H A;  1QNC A;  3OYG A;  2DKC A;  2Z0F A;  5CHZ A;  3PMG A;  3N89 A;  3LCN A;  4D7R A;  2V9J A;  3OYD A;  4AI4 A;  5HSH A;  4IKF A;  2V75 A;  4AIA A;  4UNF A;  3RSM A;  1P5D X;  2IV8 A;  3SNS A;  1KEA A;  2XHI A;  3OS2 A;  2NLV A;  1XQP A;  1XG7 A;  3OLP A;  1YQK A;  3D4V A;  2FKF A;  4E9E A;  4EAL A;  4DK9 A;  2JPI A;  3VN5 A;  1KG4 A;  1ORP A;  3N0U A;  3IHO A;  1QN7 A;  1WEG A;  3PDK A;  2VJ0 A;  4NZG A;  2QLV A;  3I3W A;  1LXT A;  4E9F A;  2YG9 A;  3I0X A;  1N3A A;  4UOB A;  2FKM X;  1YQL A;  4B22 A;  4E7K A;  2DKD A; 
#chains in the Genus database with same CATH homology
 1DIZ A;  1N3C A;  1XQO A;  4PII A;  3OH6 A;  2H56 A;  1PU8 A;  1KG7 A;  4EA4 A;  4B24 A;  2I5W A;  1KG3 A;  1M3Q A;  3I0W A;  1P7M A;  2OFK A;  1KG6 A;  3OGD A;  3CVT A;  2NOB A;  1MPG A;  1VRL A;  1NKU A;  4HSB A;  1LMZ A;  2NOE A;  4YPR A;  4E9G A;  3FSP A;  1RRS A;  1PVS A;  3CWA A;  2NOF A;  2JHJ A;  1LWW A;  1RRQ A;  3CW7 A;  4AI5 A;  3CVS A;  1FN7 A;  5KN9 A;  4EW4 A;  2OFI A;  1EBM A;  2JHN A;  4B21 A;  4B23 A;  3F0Z A;  1YQR A;  4E9H A;  3CWS A;  5CHZ A;  3CWU A;  4OFH A;  2YG8 A;  1M3H A;  3FHF A;  5KN8 A;  2NOL A;  4AI4 A;  3OH9 A;  4YPH A;  1WEI A;  1MUY A;  3KNT A;  2ABK A;  4AIA A;  4UNF A;  1ORN A;  1LWV A;  3FHG A;  1LWY A;  1KQJ A;  3CWT A;  1PU6 A;  4EJY A;  2NOH A;  1KEA A;  2XHI A;  4EA5 A;  5AN4 A;  1MUD A;  1HU0 A;  1XQP A;  1XG7 A;  3N5N X;  1YQK A;  3D4V A;  4EW0 A;  2NOI A;  4E9E A;  4DK9 A;  3G0Q A;  3KTU A;  1P59 A;  1KG4 A;  1ORP A;  3N0U A;  1YQM A;  3IHO A;  1WEG A;  4YOQ A;  1N39 A;  2NOZ A;  4EVV A;  1WEF A;  1KO9 A;  2JG6 A;  3S6I A;  3IH7 A;  1PU7 A;  4OFA A;  4E9F A;  3F10 A;  2YG9 A;  1KG2 A;  4OFE A;  3I0X A;  1NGN A;  1MUN A;  1KG5 A;  1N3A A;  4UOB A;  1YQL A;  4B22 A;  5DPK A;  4EJZ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...