3OH6A

Alka undamaged dna complex: interrogation of a c:g base pair
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
288
structure length
288
Chain Sequence
MADIGSEFYTLNWQPPYDWSWMLGFLAARAVSSVETVADSYYARSLAVGEYRGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGRLGAARPGLRLPGCVDAFEQGVRAILGQLVSVAMAAKLTARVAQLYGERLDDFPEYICFPTPQRLAAADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRWTANYFALRGWQAKDVFLPDDCLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEGWQPDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Escherichia coli AlkA in Complex with Undamaged DNA.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Escherichia coli
molecule keywords DNA-3-methyladenine glycosylase 2
total genus 87
structure length 288
sequence length 288
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 2010-08-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 3oh6A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 3oh6A03
3.30.310.20 Alpha Beta 2-Layer Sandwich TATA-Binding Protein DNA-3-methyladenine glycosylase AlkA, N-terminal domain 3oh6A01
1NKUA 2ABKA 2NOIA 1XQOA 1RRSA 4AIAA 1P59A 1N3CA 4OFHA 3CWAA 1KO9A 1LMZA 3CVSA 1LWWA 4EVVA 3IH7A 4HSBA 4B23A 3OH9A 2OFIA 1KEAA 4OFEA 1KG7A 5DPKA 1WEGA 4OFAA 2YG8A 1KQJA 3CWUA 3FHFA 3FHGA 1PU8A 3KTUA 1MUDA 4E9FA 3I0XA 1YQKA 1N3AA 2JHNA 3CVTA 3D4VA 1KG5A 2JG6A 3N5NX 4EJYA 1WEFA 2XHIA 1WEIA 2NOLA 4AI5A 4EW0A 1PU6A 1KG2A 1XG7A 1FN7A 4EA5A 4UNFA 1LWVA 4EJZA 5CHZA 3CWTA 1KG3A 5AN4A 1PU7A 4AI4A 4EA4A 5KN9A 4YPRA 4E9HA 3CWSA 3F10A 3OGDA 2NOHA 2H56A 1MUNA 1MUYA 3G0QA 3CW7A 1ORNA 4UOBA 2JHJA 1PVSA 1LWYA 1MPGA 3N0UA 1M3QA 1YQMA 1M3HA 2NOEA 1ORPA 1P7MA 3IHOA 4YPHA 1NGNA 2YG9A 3I0WA 3KNTA 1YQLA 3FSPA 2NOBA 1XQPA 1N39A 2NOZA 4PIIA 4YOQA 1KG4A 1EBMA 1KG6A 2I5WA 3S6IA 1RRQA 1VRLA 4DK9A 3F0ZA 2OFKA 2NOFA 4EW4A 4B24A 4E9EA 1DIZA 1HU0A 1YQRA 4E9GA 4B22A 4B21A 3OH6A 5KN8A
chains in the Genus database with same CATH superfamily
2HL8A 1QNEA 1XQOA 4AIAA 4OFHA 3CWAA 5FROA 4WXAA 4B23A 3UW2A 2QRDA 1YTBA 1KG7A 3VW4A 4BJUA 2MJ7A 3DPUA 3OYLA 3VN5A 1MUDA 1YTFA 4E9FA 4ZTFA 3OLPA 2PWWA 2D0BA 3HS8A 1N3AA 3CVTA 4EJYA 3L2RA 4Q11A 1WEIA 5BMPA 2NOLA 4AI5A 2FKFA 4ROCB 3OYFA 2Z0FA 3BKQX 2H5AX 1QNBA 1KYDA 1C47A 2V75A 4UNFA 2JPSA 5CHZA 1UT7A 1QTPA 4AI4A 4IKFA 4E9HA 1W80A 4NZGA 1MUNA 3G0QA 1ORNA 4EALA 1QNAA 2DKCA 2NOEA 1PCZA 3T4NA 5JMVD 1CDWA 1ORPA 4YPHA 1C4GA 1QN8A 3KRMA 1N39A 4ZTJA 4E7JA 2IV9A 3L2WA 1QN6A 2IV8A 1QNCA 3N89A 3S3NA 3DPTA 2QLVA 4B24A 3EAYA 2OOXA 5KL0A 3OH6A 3OSMA 5IYBP 2OOYA 3OYAA 3OYJA 2FUVA 1P59A 2W04A 2W03A 4EVVA 1KYUA 1VTOA 3IH7A 4HSBA 4OFEA 1PZDA 5DPKA 1WEGA 3EIKA 3OYDA 3FHGA 1PU8A 1P5DX 1AISA 3OS2A 3ASMA 2H4LX 1UL7A 2JHNA 1K35A 2JG6A 3N5NX 3OYMA 4QG5A 3ENOC 2NWVA 1PU6A 2G30A 4BACA 1FN7A 2QR1A 2ZFDB 3ENCA 4D7QA 4EJZA 4PY5A 1KG3A 3LCNA 5AN4A 3TDHA 2F7LA 1PU7A 4EA4A 5KN9A 3OSTA 3R2XC 4YPRA 2JPIA 1JFIC 3F10A 1PCJX 3CW7A 5FRNA 5JN5A 2HL9A 1MPGA 1M3HA 2NVMA 1K2YX 1P7MA 1NGNA 3OYKA 5HSHA 3I0WA 1YQLA 1U84A 1XQPA 2R5XA 2NOZA 4RODB 1B9KA 1KG4A 1EBMA 1KG6A 3OC3C 1RRQA 3PMGA 3TE5A 1VRLA 4E7KA 4DK9A 3NA5A 4EW4A 1QN7A 1T6AA 1DIZA 1QTSA 1YQRA 2V8QA 3OSEA 4E9GA 4BE1A 5EPCA 4B21A 1TBPA 2DKDA 1J3MA 2NOIA 2QRCA 1N3CA 1LMZA 2YA3A 4WX8A 1RM1A 1VKLA 3S3MA 3C04A 2OFIA 4MRQA 4C7PA 1QN3A 4HJHA 2VJ0A 3L2QA 2YG8A 3FHFA 3OYNA 2QREA 5FRMA 1YQKA 4IL8A 5IYDP 3D4VA 1KG5A 1TBAB 1WEFA 2XHIA 3OYBA 4BDYA 4ROEB 3NNQA 4BE2A 1QN5A 5IYCP 4E7HA 1KG2A 4WZSD 1LWVA 5BMNA 1R4XA 1NGMA 3H1ZA 2YH5A 1P5GX 2HZMA 1NVPA 2HKPA 1PCMX 2LAEA 3I3WA 3L2VA 1VOLB 3CWSA 1KY6A 2NOHA 1V5SA 4UOBA 2V9JA 3OYIA 2JHJA 1LWYA 1EUVA 2JOIA 1MP9A 1E42A 4CFFA 2Z8UA 2YG9A 3OYEA 3OYCA 1C9BB 1XSZA 1QN4A 1TUOA 4BDZA 1WQAA 2OFKA 2NOFA 1KFIA 4E9EA 1LXTA 2FKMX 1KYFA 4B22A 3ULXA 1UT4A 4E7LA 1TGHA 1NKUA 2ABKA 1RRSA 1KFQA 2V92A 3HS9A 1KO9A 3CVSA 1LWWA 1WJWA 2EHBD 3OH9A 1KEAA 2D0AA 3L2UA 4TPSA 4OFAA 1KQJA 3CWUA 3KTUA 4I8OA 1NH2A 1VTLE 1D3UA 3RPJA 3RSMA 3I0XA 4D7RA 4DULA 4E7IA 1JDYA 4EAGA 2Y8LA 3OS1A 4EW0A 2MZ8A 2FGTA 5F9CA 1XG7A 4EA5A 2Y8QA 2HZSA 3OS0A 3CWTA 3OGDA 2O3OA 2H56A 1MUYA 1KY7A 4EAJA 1PVSA 3N0UA 1M3QA 1YQMA 1M5Q1 2NLVA 3IHOA 3KNTA 4B0AA 3FSPA 4EAIA 1QN9A 2NOBA 1Q9UA 4EAKA 4PIIA 1VOKA 4YOQA 2I5WA 3S6IA 3SNSA 2D0CA 4BE0A 3OYHA 3F0ZA 3OYGA 3D7QA 3OCIA 3PDKA 3OY9A 1HU0A 2DKAA 5KN8A 3S3OA
chains in the Genus database with same CATH topology
1NKUA 2ABKA 2NOIA 1XQOA 1RRSA 4AIAA 1P59A 1N3CA 4OFHA 3CWAA 1KO9A 1LMZA 3CVSA 1LWWA 4EVVA 3IH7A 4HSBA 4B23A 3OH9A 2OFIA 1KEAA 4OFEA 1KG7A 5DPKA 1WEGA 4OFAA 2YG8A 1KQJA 3CWUA 3FHFA 3FHGA 1PU8A 3KTUA 1MUDA 4E9FA 3I0XA 1YQKA 1N3AA 2JHNA 3CVTA 3D4VA 1KG5A 2JG6A 3N5NX 4EJYA 1WEFA 2XHIA 1WEIA 2NOLA 4AI5A 4EW0A 1PU6A 1KG2A 1XG7A 1FN7A 4EA5A 4UNFA 1LWVA 4EJZA 5CHZA 3CWTA 1KG3A 5AN4A 1PU7A 4AI4A 4EA4A 5KN9A 4YPRA 4E9HA 3CWSA 3F10A 3OGDA 2NOHA 2H56A 1MUNA 1MUYA 3G0QA 3CW7A 1ORNA 4UOBA 2JHJA 1PVSA 1LWYA 1MPGA 3N0UA 1M3QA 1YQMA 1M3HA 2NOEA 1ORPA 1P7MA 3IHOA 4YPHA 1NGNA 2YG9A 3I0WA 3KNTA 1YQLA 3FSPA 2NOBA 1XQPA 1N39A 2NOZA 4PIIA 4YOQA 1KG4A 1EBMA 1KG6A 2I5WA 3S6IA 1RRQA 1VRLA 4DK9A 3F0ZA 2OFKA 2NOFA 4EW4A 4B24A 4E9EA 1DIZA 1HU0A 1YQRA 4E9GA 4B22A 4B21A 3OH6A 5KN8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NKU A;  2ABK A;  2NOI A;  1XQO A;  1RRS A;  4AIA A;  1P59 A;  1N3C A;  4OFH A;  3CWA A;  1KO9 A;  1LMZ A;  3CVS A;  1LWW A;  4EVV A;  3IH7 A;  4HSB A;  4B23 A;  3OH9 A;  2OFI A;  1KEA A;  4OFE A;  1KG7 A;  5DPK A;  1WEG A;  4OFA A;  2YG8 A;  1KQJ A;  3CWU A;  3FHF A;  3FHG A;  1PU8 A;  3KTU A;  1MUD A;  4E9F A;  3I0X A;  1YQK A;  1N3A A;  2JHN A;  3CVT A;  3D4V A;  1KG5 A;  2JG6 A;  3N5N X;  4EJY A;  1WEF A;  2XHI A;  1WEI A;  2NOL A;  4AI5 A;  4EW0 A;  1PU6 A;  1KG2 A;  1XG7 A;  1FN7 A;  4EA5 A;  4UNF A;  1LWV A;  4EJZ A;  5CHZ A;  3CWT A;  1KG3 A;  5AN4 A;  1PU7 A;  4AI4 A;  4EA4 A;  5KN9 A;  4YPR A;  4E9H A;  3CWS A;  3F10 A;  3OGD A;  2NOH A;  2H56 A;  1MUN A;  1MUY A;  3G0Q A;  3CW7 A;  1ORN A;  4UOB A;  2JHJ A;  1PVS A;  1LWY A;  1MPG A;  3N0U A;  1M3Q A;  1YQM A;  1M3H A;  2NOE A;  1ORP A;  1P7M A;  3IHO A;  4YPH A;  1NGN A;  2YG9 A;  3I0W A;  3KNT A;  1YQL A;  3FSP A;  2NOB A;  1XQP A;  1N39 A;  2NOZ A;  4PII A;  4YOQ A;  1KG4 A;  1EBM A;  1KG6 A;  2I5W A;  3S6I A;  1RRQ A;  1VRL A;  4DK9 A;  3F0Z A;  2OFK A;  2NOF A;  4EW4 A;  4B24 A;  4E9E A;  1DIZ A;  1HU0 A;  1YQR A;  4E9G A;  4B22 A;  4B21 A;  3OH6 A;  5KN8 A; 
#chains in the Genus database with same CATH topology
 2HL8 A;  1QNE A;  1XQO A;  4AIA A;  4OFH A;  3CWA A;  5FRO A;  4WXA A;  4B23 A;  3UW2 A;  2QRD A;  1YTB A;  1KG7 A;  3VW4 A;  4BJU A;  2MJ7 A;  3DPU A;  3OYL A;  3VN5 A;  1MUD A;  1YTF A;  4E9F A;  4ZTF A;  3OLP A;  2PWW A;  2D0B A;  3HS8 A;  1N3A A;  3CVT A;  4EJY A;  3L2R A;  4Q11 A;  1WEI A;  5BMP A;  2NOL A;  4AI5 A;  2FKF A;  4ROC B;  3OYF A;  2Z0F A;  3BKQ X;  2H5A X;  1QNB A;  1KYD A;  1C47 A;  2V75 A;  4UNF A;  2JPS A;  5CHZ A;  1UT7 A;  1QTP A;  4AI4 A;  4IKF A;  4E9H A;  1W80 A;  4NZG A;  1MUN A;  3G0Q A;  1ORN A;  4EAL A;  1QNA A;  2DKC A;  2NOE A;  1PCZ A;  3T4N A;  5JMV D;  1CDW A;  1ORP A;  4YPH A;  1C4G A;  1QN8 A;  3KRM A;  1N39 A;  4ZTJ A;  4E7J A;  2IV9 A;  3L2W A;  1QN6 A;  2IV8 A;  1QNC A;  3N89 A;  3S3N A;  3DPT A;  2QLV A;  4B24 A;  3EAY A;  2OOX A;  5KL0 A;  3OH6 A;  3OSM A;  5IYB P;  2OOY A;  3OYA A;  3OYJ A;  2FUV A;  1P59 A;  2W04 A;  2W03 A;  4EVV A;  1KYU A;  1VTO A;  3IH7 A;  4HSB A;  4OFE A;  1PZD A;  5DPK A;  1WEG A;  3EIK A;  3OYD A;  3FHG A;  1PU8 A;  1P5D X;  1AIS A;  3OS2 A;  3ASM A;  2H4L X;  1UL7 A;  2JHN A;  1K35 A;  2JG6 A;  3N5N X;  3OYM A;  4QG5 A;  3ENO C;  2NWV A;  1PU6 A;  2G30 A;  4BAC A;  1FN7 A;  2QR1 A;  2ZFD B;  3ENC A;  4D7Q A;  4EJZ A;  4PY5 A;  1KG3 A;  3LCN A;  5AN4 A;  3TDH A;  2F7L A;  1PU7 A;  4EA4 A;  5KN9 A;  3OST A;  3R2X C;  4YPR A;  2JPI A;  1JFI C;  3F10 A;  1PCJ X;  3CW7 A;  5FRN A;  5JN5 A;  2HL9 A;  1MPG A;  1M3H A;  2NVM A;  1K2Y X;  1P7M A;  1NGN A;  3OYK A;  5HSH A;  3I0W A;  1YQL A;  1U84 A;  1XQP A;  2R5X A;  2NOZ A;  4ROD B;  1B9K A;  1KG4 A;  1EBM A;  1KG6 A;  3OC3 C;  1RRQ A;  3PMG A;  3TE5 A;  1VRL A;  4E7K A;  4DK9 A;  3NA5 A;  4EW4 A;  1QN7 A;  1T6A A;  1DIZ A;  1QTS A;  1YQR A;  2V8Q A;  3OSE A;  4E9G A;  4BE1 A;  5EPC A;  4B21 A;  1TBP A;  2DKD A;  1J3M A;  2NOI A;  2QRC A;  1N3C A;  1LMZ A;  2YA3 A;  4WX8 A;  1RM1 A;  1VKL A;  3S3M A;  3C04 A;  2OFI A;  4MRQ A;  4C7P A;  1QN3 A;  4HJH A;  2VJ0 A;  3L2Q A;  2YG8 A;  3FHF A;  3OYN A;  2QRE A;  5FRM A;  1YQK A;  4IL8 A;  5IYD P;  3D4V A;  1KG5 A;  1TBA B;  1WEF A;  2XHI A;  3OYB A;  4BDY A;  4ROE B;  3NNQ A;  4BE2 A;  1QN5 A;  5IYC P;  4E7H A;  1KG2 A;  4WZS D;  1LWV A;  5BMN A;  1R4X A;  1NGM A;  3H1Z A;  2YH5 A;  1P5G X;  2HZM A;  1NVP A;  2HKP A;  1PCM X;  2LAE A;  3I3W A;  3L2V A;  1VOL B;  3CWS A;  1KY6 A;  2NOH A;  1V5S A;  4UOB A;  2V9J A;  3OYI A;  2JHJ A;  1LWY A;  1EUV A;  2JOI A;  1MP9 A;  1E42 A;  4CFF A;  2Z8U A;  2YG9 A;  3OYE A;  3OYC A;  1C9B B;  1XSZ A;  1QN4 A;  1TUO A;  4BDZ A;  1WQA A;  2OFK A;  2NOF A;  1KFI A;  4E9E A;  1LXT A;  2FKM X;  1KYF A;  4B22 A;  3ULX A;  1UT4 A;  4E7L A;  1TGH A;  1NKU A;  2ABK A;  1RRS A;  1KFQ A;  2V92 A;  3HS9 A;  1KO9 A;  3CVS A;  1LWW A;  1WJW A;  2EHB D;  3OH9 A;  1KEA A;  2D0A A;  3L2U A;  4TPS A;  4OFA A;  1KQJ A;  3CWU A;  3KTU A;  4I8O A;  1NH2 A;  1VTL E;  1D3U A;  3RPJ A;  3RSM A;  3I0X A;  4D7R A;  4DUL A;  4E7I A;  1JDY A;  4EAG A;  2Y8L A;  3OS1 A;  4EW0 A;  2MZ8 A;  2FGT A;  5F9C A;  1XG7 A;  4EA5 A;  2Y8Q A;  2HZS A;  3OS0 A;  3CWT A;  3OGD A;  2O3O A;  2H56 A;  1MUY A;  1KY7 A;  4EAJ A;  1PVS A;  3N0U A;  1M3Q A;  1YQM A;  1M5Q 1;  2NLV A;  3IHO A;  3KNT A;  4B0A A;  3FSP A;  4EAI A;  1QN9 A;  2NOB A;  1Q9U A;  4EAK A;  4PII A;  1VOK A;  4YOQ A;  2I5W A;  3S6I A;  3SNS A;  2D0C A;  4BE0 A;  3OYH A;  3F0Z A;  3OYG A;  3D7Q A;  3OCI A;  3PDK A;  3OY9 A;  1HU0 A;  2DKA A;  5KN8 A;  3S3O A; 
#chains in the Genus database with same CATH homology
 1NKU A;  2ABK A;  2NOI A;  1XQO A;  1RRS A;  4AIA A;  1P59 A;  1N3C A;  4OFH A;  3CWA A;  1KO9 A;  1LMZ A;  3CVS A;  1LWW A;  4EVV A;  3IH7 A;  4HSB A;  4B23 A;  3OH9 A;  2OFI A;  1KEA A;  4OFE A;  1KG7 A;  5DPK A;  1WEG A;  4OFA A;  2YG8 A;  1KQJ A;  3CWU A;  3FHF A;  3FHG A;  1PU8 A;  3KTU A;  1MUD A;  4E9F A;  3I0X A;  1YQK A;  1N3A A;  2JHN A;  3CVT A;  3D4V A;  1KG5 A;  2JG6 A;  3N5N X;  4EJY A;  1WEF A;  2XHI A;  1WEI A;  2NOL A;  4AI5 A;  4EW0 A;  1PU6 A;  1KG2 A;  1XG7 A;  1FN7 A;  4EA5 A;  4UNF A;  1LWV A;  4EJZ A;  5CHZ A;  3CWT A;  1KG3 A;  5AN4 A;  1PU7 A;  4AI4 A;  4EA4 A;  5KN9 A;  4YPR A;  4E9H A;  3CWS A;  3F10 A;  3OGD A;  2NOH A;  2H56 A;  1MUN A;  1MUY A;  3G0Q A;  3CW7 A;  1ORN A;  4UOB A;  2JHJ A;  1PVS A;  1LWY A;  1MPG A;  3N0U A;  1M3Q A;  1YQM A;  1M3H A;  2NOE A;  1ORP A;  1P7M A;  3IHO A;  4YPH A;  1NGN A;  2YG9 A;  3I0W A;  3KNT A;  1YQL A;  3FSP A;  2NOB A;  1XQP A;  1N39 A;  2NOZ A;  4PII A;  4YOQ A;  1KG4 A;  1EBM A;  1KG6 A;  2I5W A;  3S6I A;  1RRQ A;  1VRL A;  4DK9 A;  3F0Z A;  2OFK A;  2NOF A;  4EW4 A;  4B24 A;  4E9E A;  1DIZ A;  1HU0 A;  1YQR A;  4E9G A;  4B22 A;  4B21 A;  3OH6 A;  5KN8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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