1MZ8A

Crystal structures of the nuclease domain of cole7/im7 in complex with a phosphate ion and a zinc ion
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
87
structure length
87
Chain Sequence
MELKNSISDYTEAEFVQLLKEIEKENVAATDDVLDVLLEHFVKITEHPDGTDLIYYPSDNRDDSPEGIVKEIKEWRAANGKPGFKQG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Metal ions and phosphate binding in the H-N-H motif: crystal structures of the nuclease domain of ColE7/Im7 in complex with a phosphate ion and different divalent metal ions
pubmed doi rcsb
molecule tags Toxin,hydrolase/protein binding
source organism Escherichia coli
molecule keywords Colicin E7 immunity protein
total genus 30
structure length 87
sequence length 87
chains with identical sequence C
ec nomenclature
pdb deposition date 2002-10-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01320 Colicin_Pyocin Colicin immunity protein / pyocin immunity protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.20 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Colicin E immunity protein 1mz8A00
2JB0A 2NO8A 2JBGA 1IMPA 7CEIA 1UJZA 3GJNA 1UNKA 3U43A 2JAZA 4QKOA 2GYKA 1AYIA 1CEIA 2VLOA 3GKLC 5EW5E 1GXHA 1EMVA 4UHPB 2VLPA 2K0DX 1ZNVA 2K5XA 1BXIA 2VLNA 1GXGA 2GZEA 2GZFA 1FR2A 4F37A 2ERHA 2GZJA 2GZIA 1MZ8A 2WPTA 1IMQA 1E0HA 2GZGA 2VLQA
chains in the Genus database with same CATH superfamily
2L22A 2MR7A 1E6JP 5HV8A 7CEIA 2K93A 1AF8A 3I55P 2GDYA 4NEOA 4WYMA 3EJDA 5I4TG 2L0QA 2M8NA 3CC4P 2CQ8A 2KGCA 4F37A 5HGOA 1YJWP 2CG5B 2GZGA 2KOSA 1K73Q 2L6EA 1GPJA 1Q81Q 1DV5A 1KD1Q 1VQ4P 1M6NA 3VRLC 1YHQP 1VQOP 4HKGA 1VQ5P 3P05A 1M90Q 2JBGA 2MF4A 2OARA 2FADA 2FQ2A 3GZMA 1YJNP 3DPHA 2GDWA 1BXIA 5DCKA 2GZEA 1BAJA 2MR8A 2N6ZA 4BPFA 2FACA 4U0CA 3CCJP 1S72P 3CC7P 5HVCA 1AYIA 2GYKA 3B5IA 3DTJA 2PEQA 4QNBA 2JU1A 5F2OA 1K30A 2FQ0A 4H2WC 2LL8A 2M5RA 2KR5A 1UJZA 3MGEA 3I56P 2QNWA 3G26A 2JAZA 1A8OA 4MRTC 3WBHA 2PENA 5HGMA 2KWLA 3OW2O 3LRYA 2LTEA 2AVAA 1T8KA 3M1MA 2KG8A 2N5IA 5HGLA 2XV6A 1N8RQ 3GZLA 2NO8A 4U0BA 3CXCO 3CC2P 2KOQA 5F2KA 3HYBA 1KC8Q 2LIUA 1DNYA 2EHSA 3EJEA 3CCLP 4PH1A 2AFEA 2MY5A 2K94A 2KGEA 2OTJP 2VSQA 2JGPA 1VQNP 1IMQA 1E0HA 3CPWO 5EJDA 2E1MA 5KP6B 1VQ8P 1IMPA 1M6EX 1RO0A 2CWOA 1KLPA 1CEIA 1A43A 4IPYA 1GXHA 1EOQA 2LF4A 4H2YC 3E2DA 5KP8B 1Z6MA 2Z44A 4XRQA 1YITP 3Q20A 3U43A 3DS2A 2FVAA 2K2QA 1QVGO 4UHPB 2BHVA 4PH0A 2FVEA 1FR2A 2AFDA 4COCA 2JYGA 2K92A 2EFJA 2KGDA 3G0VA 3CD6P 2KG9A 2K0YA 1K8AQ 3DS0A 2VLOA 2ONTA 3DS4A 5EW5E 1Q7YQ 2X2BA 3NY7B 2FVFA 2EIAA 3G1GA 3RG6C 3CCMP 5CZDB 2QA4P 3CCEP 4GR2A 1VQ6P 2P9XA 1X3OA 2QEXP 2XT1A 4DG9A 1VQPP 2PEIA 3CCVP 1RO2A 4U0FA 1AUMA 1QVFO 2XXMA 2MVVA 2GZFA 2ERHA 3RG2A 4BPGA 5JPAA 3B4QA 2PEMA 4CA3A 1KQSO 1K9MQ 2L9FA 3HZQA 2GDXA 2M8PA 1L0IA 2N98A 2EG5A 2JYLA 2PEKA 4IZ6A 2KOOA 2JQ4A 2K0DX 4R0MA 5HGNA 4M0IA 4COPA 2N5HA 1VKUA 2M8LA 1Q86Q 2PNGA 4XFXA 2Z46A 2OTLP 2DGYA 2Z45A 4BPHA 3G29A 3LMOA 3NTEA 2K5XA 2XZ1C 3H0DA 5KP7B 1HY8A 1MZ8A 2PEJA 3G28A 3G21A 1ACPA 3CMEP 2VLQA 2DNWA 3CMAP 1JJ2O 1HQBA 2CNRA 2MVUA 2LPKA 2N50A 1F80D 2KORA 4PXHB 5BS1A 2PY8A 4XFZA 5F2NA 2LMLA 2JU2A 1VQKP 2L4BA 2KOPA 2KW2A 1YJ9P 1NQ4A 2LIWA 2GZIA 2PEOA 1RNIA 4U0DA 3DS1A 3DS5A 3DS3A 4H2XC 1W2BO 2JB0A 4PWVB 3EJBA 4GR6A 4XFYA 1UNKA 4U0EA 2AF8A 1M74A 2JO0A 2LKIA 2EHTA 1EMVA 2VLPA 3G1IA 1Q82Q 1GXGA 1VQ7P 1QRJA 4XROA 1EIAA 3H47A 3G6EP 2XZ0D 2N6YA 4QKOA 3CCRP 3GKLC 2FHSC 1D1DA 3CE7A 1ZMBA 3G71P 1YIJP 2WPTA 1IUQA 4U0AA 1NJIQ 2CGQA 2KG6A 1VQMP 1YI2P 2KGAA 2MD9A 1L0HA 3GJNA 1M1KQ 2KODA 2FAEA 2LOLA 3H4EA 3CCQP 3CCSP 3G4SP 1ZNVA 2VLNA 5BS2A 2GZJA 1VQ9P 3CCUP 2ROQA 1OR5A 2BUOA 2FQ1A 1VQLP 1VHNA 2K0XA
chains in the Genus database with same CATH topology
2JB0A 2NO8A 2JBGA 1IMPA 7CEIA 1UJZA 3GJNA 1UNKA 3U43A 2JAZA 4QKOA 2GYKA 1AYIA 1CEIA 2VLOA 3GKLC 5EW5E 1GXHA 1EMVA 4UHPB 2VLPA 2K0DX 1ZNVA 2K5XA 1BXIA 2VLNA 1GXGA 2GZEA 2GZFA 1FR2A 4F37A 2ERHA 2GZJA 2GZIA 1MZ8A 2WPTA 1IMQA 1E0HA 2GZGA 2VLQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JB0 A;  2NO8 A;  2JBG A;  1IMP A;  7CEI A;  1UJZ A;  3GJN A;  1UNK A;  3U43 A;  2JAZ A;  4QKO A;  2GYK A;  1AYI A;  1CEI A;  2VLO A;  3GKL C;  5EW5 E;  1GXH A;  1EMV A;  4UHP B;  2VLP A;  2K0D X;  1ZNV A;  2K5X A;  1BXI A;  2VLN A;  1GXG A;  2GZE A;  2GZF A;  1FR2 A;  4F37 A;  2ERH A;  2GZJ A;  2GZI A;  1MZ8 A;  2WPT A;  1IMQ A;  1E0H A;  2GZG A;  2VLQ A; 
#chains in the Genus database with same CATH topology
 2L22 A;  2MR7 A;  1E6J P;  5HV8 A;  7CEI A;  2K93 A;  1AF8 A;  3I55 P;  2GDY A;  4NEO A;  4WYM A;  3EJD A;  5I4T G;  2L0Q A;  2M8N A;  3CC4 P;  2CQ8 A;  2KGC A;  4F37 A;  5HGO A;  1YJW P;  2CG5 B;  2GZG A;  2KOS A;  1K73 Q;  2L6E A;  1GPJ A;  1Q81 Q;  1DV5 A;  1KD1 Q;  1VQ4 P;  1M6N A;  3VRL C;  1YHQ P;  1VQO P;  4HKG A;  1VQ5 P;  3P05 A;  1M90 Q;  2JBG A;  2MF4 A;  2OAR A;  2FAD A;  2FQ2 A;  3GZM A;  1YJN P;  3DPH A;  2GDW A;  1BXI A;  5DCK A;  2GZE A;  1BAJ A;  2MR8 A;  2N6Z A;  4BPF A;  2FAC A;  4U0C A;  3CCJ P;  1S72 P;  3CC7 P;  5HVC A;  1AYI A;  2GYK A;  3B5I A;  3DTJ A;  2PEQ A;  4QNB A;  2JU1 A;  5F2O A;  1K30 A;  2FQ0 A;  4H2W C;  2LL8 A;  2M5R A;  2KR5 A;  1UJZ A;  3MGE A;  3I56 P;  2QNW A;  3G26 A;  2JAZ A;  1A8O A;  4MRT C;  3WBH A;  2PEN A;  5HGM A;  2KWL A;  3OW2 O;  3LRY A;  2LTE A;  2AVA A;  1T8K A;  3M1M A;  2KG8 A;  2N5I A;  5HGL A;  2XV6 A;  1N8R Q;  3GZL A;  2NO8 A;  4U0B A;  3CXC O;  3CC2 P;  2KOQ A;  5F2K A;  3HYB A;  1KC8 Q;  2LIU A;  1DNY A;  2EHS A;  3EJE A;  3CCL P;  4PH1 A;  2AFE A;  2MY5 A;  2K94 A;  2KGE A;  2OTJ P;  2VSQ A;  2JGP A;  1VQN P;  1IMQ A;  1E0H A;  3CPW O;  5EJD A;  2E1M A;  5KP6 B;  1VQ8 P;  1IMP A;  1M6E X;  1RO0 A;  2CWO A;  1KLP A;  1CEI A;  1A43 A;  4IPY A;  1GXH A;  1EOQ A;  2LF4 A;  4H2Y C;  3E2D A;  5KP8 B;  1Z6M A;  2Z44 A;  4XRQ A;  1YIT P;  3Q20 A;  3U43 A;  3DS2 A;  2FVA A;  2K2Q A;  1QVG O;  4UHP B;  2BHV A;  4PH0 A;  2FVE A;  1FR2 A;  2AFD A;  4COC A;  2JYG A;  2K92 A;  2EFJ A;  2KGD A;  3G0V A;  3CD6 P;  2KG9 A;  2K0Y A;  1K8A Q;  3DS0 A;  2VLO A;  2ONT A;  3DS4 A;  5EW5 E;  1Q7Y Q;  2X2B A;  3NY7 B;  2FVF A;  2EIA A;  3G1G A;  3RG6 C;  3CCM P;  5CZD B;  2QA4 P;  3CCE P;  4GR2 A;  1VQ6 P;  2P9X A;  1X3O A;  2QEX P;  2XT1 A;  4DG9 A;  1VQP P;  2PEI A;  3CCV P;  1RO2 A;  4U0F A;  1AUM A;  1QVF O;  2XXM A;  2MVV A;  2GZF A;  2ERH A;  3RG2 A;  4BPG A;  5JPA A;  3B4Q A;  2PEM A;  4CA3 A;  1KQS O;  1K9M Q;  2L9F A;  3HZQ A;  2GDX A;  2M8P A;  1L0I A;  2N98 A;  2EG5 A;  2JYL A;  2PEK A;  4IZ6 A;  2KOO A;  2JQ4 A;  2K0D X;  4R0M A;  5HGN A;  4M0I A;  4COP A;  2N5H A;  1VKU A;  2M8L A;  1Q86 Q;  2PNG A;  4XFX A;  2Z46 A;  2OTL P;  2DGY A;  2Z45 A;  4BPH A;  3G29 A;  3LMO A;  3NTE A;  2K5X A;  2XZ1 C;  3H0D A;  5KP7 B;  1HY8 A;  1MZ8 A;  2PEJ A;  3G28 A;  3G21 A;  1ACP A;  3CME P;  2VLQ A;  2DNW A;  3CMA P;  1JJ2 O;  1HQB A;  2CNR A;  2MVU A;  2LPK A;  2N50 A;  1F80 D;  2KOR A;  4PXH B;  5BS1 A;  2PY8 A;  4XFZ A;  5F2N A;  2LML A;  2JU2 A;  1VQK P;  2L4B A;  2KOP A;  2KW2 A;  1YJ9 P;  1NQ4 A;  2LIW A;  2GZI A;  2PEO A;  1RNI A;  4U0D A;  3DS1 A;  3DS5 A;  3DS3 A;  4H2X C;  1W2B O;  2JB0 A;  4PWV B;  3EJB A;  4GR6 A;  4XFY A;  1UNK A;  4U0E A;  2AF8 A;  1M74 A;  2JO0 A;  2LKI A;  2EHT A;  1EMV A;  2VLP A;  3G1I A;  1Q82 Q;  1GXG A;  1VQ7 P;  1QRJ A;  4XRO A;  1EIA A;  3H47 A;  3G6E P;  2XZ0 D;  2N6Y A;  4QKO A;  3CCR P;  3GKL C;  2FHS C;  1D1D A;  3CE7 A;  1ZMB A;  3G71 P;  1YIJ P;  2WPT A;  1IUQ A;  4U0A A;  1NJI Q;  2CGQ A;  2KG6 A;  1VQM P;  1YI2 P;  2KGA A;  2MD9 A;  1L0H A;  3GJN A;  1M1K Q;  2KOD A;  2FAE A;  2LOL A;  3H4E A;  3CCQ P;  3CCS P;  3G4S P;  1ZNV A;  2VLN A;  5BS2 A;  2GZJ A;  1VQ9 P;  3CCU P;  2ROQ A;  1OR5 A;  2BUO A;  2FQ1 A;  1VQL P;  1VHN A;  2K0X A; 
#chains in the Genus database with same CATH homology
 2JB0 A;  2NO8 A;  2JBG A;  1IMP A;  7CEI A;  1UJZ A;  3GJN A;  1UNK A;  3U43 A;  2JAZ A;  4QKO A;  2GYK A;  1AYI A;  1CEI A;  2VLO A;  3GKL C;  5EW5 E;  1GXH A;  1EMV A;  4UHP B;  2VLP A;  2K0D X;  1ZNV A;  2K5X A;  1BXI A;  2VLN A;  1GXG A;  2GZE A;  2GZF A;  1FR2 A;  4F37 A;  2ERH A;  2GZJ A;  2GZI A;  1MZ8 A;  2WPT A;  1IMQ A;  1E0H A;  2GZG A;  2VLQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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