2KGEA

Nmr solution structures of 3,5-dioxohexyl acp (a triketide mimic) from the actinorhodin polyketide synthase in streptomyces coelicolor
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
86
structure length
86
Chain Sequence
MATLLTTDDLRRALVESAGETDGTDLSGDFLDLRFEDIGYDSLALMETAARLESRYGVSIPDDVAGRVDTPRELLDLINGALAEAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Biosynthetic protein
molecule keywords Actinorhodin polyketide synthase acyl carrier protein
publication title Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
pubmed doi rcsb
source organism Streptomyces coelicolor
total genus 22
structure length 86
sequence length 86
ec nomenclature
pdb deposition date 2009-03-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 2kgeA00
2QNWA 1L0HA 2LOLA 2FACA 3RG2A 4PXHB 1AF8A 2JU1A 2LMLA 2MR7A 4HKGA 2FVFA 2K0XA 1DV5A 2AVAA 2MD9A 2X2BA 1HQBA 4CA3A 2KGDA 5HV8A 2KG9A 2N50A 3GZLA 1T8KA 1X3OA 1KLPA 2K2QA 2LKIA 2AFEA 4BPHA 2EHTA 4H2XC 2CQ8A 2GDYA 2XZ1C 2LL8A 2LTEA 1HY8A 2GDWA 2VSQA 2K0YA 2MF4A 5EJDA 5CZDB 2MVUA 4H2YC 2FHSC 2KGEA 3EJBA 2FAEA 2KG6A 2CNRA 2FADA 2JGPA 2AFDA 4IZ6A 1NQ4A 2LIUA 2KW2A 2KR5A 2M5RA 3LMOA 2N6YA 1L0IA 2LPKA 2MY5A 1OR5A 2EHSA 4BPFA 1F80D 2FVAA 1DNYA 2L22A 1ACPA 1VKUA 4H2WC 2K93A 4NEOA 4DG9A 5KP6B 5KP7B 2PNGA 2LIWA 2FQ1A 5KP8B 3CE7A 2KG8A 2L0QA 2N6ZA 2XZ0D 3GZMA 3NY7B 2MVVA 5HVCA 2KOSA 4MRTC 2JU2A 2N98A 2MR8A 4BPGA 2CGQA 2K94A 2L9FA 4R0MA 2L4BA 2FQ0A 2ROQA 2JQ4A 2N5IA 2DNWA 2KOQA 2FQ2A 4PWVB 2KWLA 3EJEA 2GDXA 2KOOA 2KGCA 2CG5B 2FVEA 2N5HA 3EJDA 2K92A 2AF8A 2KGAA 2KORA 2KOPA
chains in the Genus database with same CATH superfamily
2QNWA 2LOLA 4M0IA 2JU1A 2FVFA 3CC7P 4XRQA 1IMPA 1GXHA 3G1IA 2GZEA 4U0AA 1T8KA 1ZNVA 2OARA 4GR2A 1W2BO 1KLPA 2K5XA 1K8AQ 1Q7YQ 2CQ8A 1E0HA 1HY8A 1UNKA 1M1KQ 3VRLC 2MVUA 2GZFA 1M90Q 3CCVP 1VHNA 3CCUP 2BUOA 2AFDA 1IMQA 3CCMP 1NQ4A 2LIUA 1YIJP 1A43A 3E2DA 1VQPP 2M5RA 1YJNP 2PEMA 1VQNP 3LMOA 1L0IA 2EFJA 3CCEP 3OW2O 4H2WC 4NEOA 5KP6B 4U0BA 2PNGA 3RG6C 1YHQP 3CE7A 5BS2A 2N6ZA 3NY7B 2MVVA 2KOSA 3WBHA 2LF4A 1M74A 2PEOA 2NO8A 2WPTA 4R0MA 2L4BA 1S72P 2ROQA 3EJEA 3CCQP 1YI2P 1IUQA 2KGAA 1KD1Q 2KOPA 2FACA 4PXHB 1QVGO 2GZJA 2PEKA 1RO0A 2K0XA 3CXCO 2AVAA 2X2BA 4CA3A 1GXGA 5HV8A 2KG9A 1X3OA 3DS4A 2XZ1C 1VQ9P 2PEQA 5CZDB 2K0YA 1EOQA 3DS2A 5EJDA 2KGEA 3EJBA 2FAEA 3G1GA 4PH0A 4XFYA 2JGPA 4IZ6A 4U0EA 2XT1A 3B4QA 2Z44A 2GYKA 3U43A 2OTLP 3HZQA 4BPFA 1F80D 1DNYA 2EIAA 2L6EA 1UJZA 3CCJP 2QA4P 2K93A 3CCSP 1VQ5P 1BAJA 3H4EA 4DG9A 1JJ2O 2FQ1A 1KC8Q 5KP8B 3NTEA 5HVCA 3G28A 2EG5A 2JU2A 2N98A 1VQ8P 2DGYA 1VQLP 3G29A 2K94A 2K0DX 2PEJA 3LRYA 1RNIA 1CEIA 2DNWA 3G71P 2FQ2A 4PWVB 2GDXA 1N8RQ 2KGCA 2QEXP 2CG5B 2N5HA 3P05A 5I4TG 1D1DA 5HGOA 3RG2A 1AF8A 2LMLA 2M8NA 3DTJA 4HKGA 3B5IA 5DCKA 1DV5A 2CWOA 3G21A 2JYGA 1HQBA 7CEIA 1E6JP 3CD6P 3G26A 2KODA 2AFEA 2EHTA 1M6EX 2JYLA 2ONTA 2LTEA 4WYMA 2GDWA 2MF4A 2JBGA 3DPHA 3Q20A 3CPWO 1EMVA 2FHSC 2PY8A 5HGMA 2KG6A 2JO0A 2CNRA 3G0VA 2FADA 1Q82Q 2KW2A 2BHVA 1Q81Q 3DS3A 5F2OA 4UHPB 2M8LA 3G6EP 1VQOP 3I56P 1OR5A 5HGLA 2FVAA 1EIAA 2L22A 1ACPA 1QVFO 1VKUA 2VLPA 2LIWA 1A8OA 3CC2P 2VLOA 2KG8A 5BS1A 1Z6MA 3GZMA 3GKLC 4MRTC 1KQSO 4QKOA 3DS5A 2CGQA 4U0FA 2XV6A 2FQ0A 1QRJA 2JQ4A 2KOQA 5EW5E 1VQKP 2OTJP 4COCA 1VQ6P 1BXIA 4PH1A 2K92A 2AF8A 1L0HA 3GJNA 2MR7A 2PENA 2MD9A 4XFZA 3M1MA 4QNBA 3CMAP 2JAZA 5F2NA 2KGDA 2N50A 3GZLA 2GZIA 1RO2A 2K2QA 2LKIA 4F37A 4BPHA 4H2XC 3CC4P 2GDYA 4XROA 2VLNA 1MZ8A 1YJ9P 2LL8A 2Z45A 4COPA 2VSQA 1FR2A 3DS1A 1K9MQ 2GZGA 2XXMA 4U0DA 5HGNA 3H0DA 4H2YC 4GR6A 3CMEP 1YITP 2M8PA 3CCRP 1M6NA 1Q86Q 2P9XA 3I55P 4IPYA 5JPAA 2KR5A 1AUMA 1K73Q 3MGEA 2N6YA 2LPKA 2MY5A 2EHSA 1GPJA 5F2KA 1AYIA 2E1MA 1ZMBA 1VQ4P 1VQMP 3G4SP 5KP7B 3CCLP 3HYBA 2L0QA 2XZ0D 2MR8A 2ERHA 4BPGA 2L9FA 2JB0A 2N5IA 1K30A 1YJWP 3H47A 4U0CA 2KWLA 1NJIQ 2VLQA 4XFXA 2Z46A 2KOOA 2FVEA 3DS0A 3EJDA 1VQ7P 2KORA 2PEIA
chains in the Genus database with same CATH topology
2QNWA 1L0HA 2LOLA 2FACA 3RG2A 4PXHB 1AF8A 2JU1A 2LMLA 2MR7A 4HKGA 2FVFA 2K0XA 1DV5A 2AVAA 2MD9A 2X2BA 1HQBA 4CA3A 2KGDA 5HV8A 2KG9A 2N50A 3GZLA 1T8KA 1X3OA 1KLPA 2K2QA 2LKIA 2AFEA 4BPHA 2EHTA 4H2XC 2CQ8A 2GDYA 2XZ1C 2LL8A 2LTEA 1HY8A 2GDWA 2VSQA 2K0YA 2MF4A 5EJDA 5CZDB 2MVUA 4H2YC 2FHSC 2KGEA 3EJBA 2FAEA 2KG6A 2CNRA 2FADA 2JGPA 2AFDA 4IZ6A 1NQ4A 2LIUA 2KW2A 2KR5A 2M5RA 3LMOA 2N6YA 1L0IA 2LPKA 2MY5A 1OR5A 2EHSA 4BPFA 1F80D 2FVAA 1DNYA 2L22A 1ACPA 1VKUA 4H2WC 2K93A 4NEOA 4DG9A 5KP6B 5KP7B 2PNGA 2LIWA 2FQ1A 5KP8B 3CE7A 2KG8A 2L0QA 2N6ZA 2XZ0D 3GZMA 3NY7B 2MVVA 5HVCA 2KOSA 4MRTC 2JU2A 2N98A 2MR8A 4BPGA 2CGQA 2K94A 2L9FA 4R0MA 2L4BA 2FQ0A 2ROQA 2JQ4A 2N5IA 2DNWA 2KOQA 2FQ2A 4PWVB 2KWLA 3EJEA 2GDXA 2KOOA 2KGCA 2CG5B 2FVEA 2N5HA 3EJDA 2K92A 2AF8A 2KGAA 2KORA 2KOPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QNW A;  1L0H A;  2LOL A;  2FAC A;  3RG2 A;  4PXH B;  1AF8 A;  2JU1 A;  2LML A;  2MR7 A;  4HKG A;  2FVF A;  2K0X A;  1DV5 A;  2AVA A;  2MD9 A;  2X2B A;  1HQB A;  4CA3 A;  2KGD A;  5HV8 A;  2KG9 A;  2N50 A;  3GZL A;  1T8K A;  1X3O A;  1KLP A;  2K2Q A;  2LKI A;  2AFE A;  4BPH A;  2EHT A;  4H2X C;  2CQ8 A;  2GDY A;  2XZ1 C;  2LL8 A;  2LTE A;  1HY8 A;  2GDW A;  2VSQ A;  2K0Y A;  2MF4 A;  5EJD A;  5CZD B;  2MVU A;  4H2Y C;  2FHS C;  2KGE A;  3EJB A;  2FAE A;  2KG6 A;  2CNR A;  2FAD A;  2JGP A;  2AFD A;  4IZ6 A;  1NQ4 A;  2LIU A;  2KW2 A;  2KR5 A;  2M5R A;  3LMO A;  2N6Y A;  1L0I A;  2LPK A;  2MY5 A;  1OR5 A;  2EHS A;  4BPF A;  1F80 D;  2FVA A;  1DNY A;  2L22 A;  1ACP A;  1VKU A;  4H2W C;  2K93 A;  4NEO A;  4DG9 A;  5KP6 B;  5KP7 B;  2PNG A;  2LIW A;  2FQ1 A;  5KP8 B;  3CE7 A;  2KG8 A;  2L0Q A;  2N6Z A;  2XZ0 D;  3GZM A;  3NY7 B;  2MVV A;  5HVC A;  2KOS A;  4MRT C;  2JU2 A;  2N98 A;  2MR8 A;  4BPG A;  2CGQ A;  2K94 A;  2L9F A;  4R0M A;  2L4B A;  2FQ0 A;  2ROQ A;  2JQ4 A;  2N5I A;  2DNW A;  2KOQ A;  2FQ2 A;  4PWV B;  2KWL A;  3EJE A;  2GDX A;  2KOO A;  2KGC A;  2CG5 B;  2FVE A;  2N5H A;  3EJD A;  2K92 A;  2AF8 A;  2KGA A;  2KOR A;  2KOP A; 
#chains in the Genus database with same CATH topology
 2QNW A;  2LOL A;  4M0I A;  2JU1 A;  2FVF A;  3CC7 P;  4XRQ A;  1IMP A;  1GXH A;  3G1I A;  2GZE A;  4U0A A;  1T8K A;  1ZNV A;  2OAR A;  4GR2 A;  1W2B O;  1KLP A;  2K5X A;  1K8A Q;  1Q7Y Q;  2CQ8 A;  1E0H A;  1HY8 A;  1UNK A;  1M1K Q;  3VRL C;  2MVU A;  2GZF A;  1M90 Q;  3CCV P;  1VHN A;  3CCU P;  2BUO A;  2AFD A;  1IMQ A;  3CCM P;  1NQ4 A;  2LIU A;  1YIJ P;  1A43 A;  3E2D A;  1VQP P;  2M5R A;  1YJN P;  2PEM A;  1VQN P;  3LMO A;  1L0I A;  2EFJ A;  3CCE P;  3OW2 O;  4H2W C;  4NEO A;  5KP6 B;  4U0B A;  2PNG A;  3RG6 C;  1YHQ P;  3CE7 A;  5BS2 A;  2N6Z A;  3NY7 B;  2MVV A;  2KOS A;  3WBH A;  2LF4 A;  1M74 A;  2PEO A;  2NO8 A;  2WPT A;  4R0M A;  2L4B A;  1S72 P;  2ROQ A;  3EJE A;  3CCQ P;  1YI2 P;  1IUQ A;  2KGA A;  1KD1 Q;  2KOP A;  2FAC A;  4PXH B;  1QVG O;  2GZJ A;  2PEK A;  1RO0 A;  2K0X A;  3CXC O;  2AVA A;  2X2B A;  4CA3 A;  1GXG A;  5HV8 A;  2KG9 A;  1X3O A;  3DS4 A;  2XZ1 C;  1VQ9 P;  2PEQ A;  5CZD B;  2K0Y A;  1EOQ A;  3DS2 A;  5EJD A;  2KGE A;  3EJB A;  2FAE A;  3G1G A;  4PH0 A;  4XFY A;  2JGP A;  4IZ6 A;  4U0E A;  2XT1 A;  3B4Q A;  2Z44 A;  2GYK A;  3U43 A;  2OTL P;  3HZQ A;  4BPF A;  1F80 D;  1DNY A;  2EIA A;  2L6E A;  1UJZ A;  3CCJ P;  2QA4 P;  2K93 A;  3CCS P;  1VQ5 P;  1BAJ A;  3H4E A;  4DG9 A;  1JJ2 O;  2FQ1 A;  1KC8 Q;  5KP8 B;  3NTE A;  5HVC A;  3G28 A;  2EG5 A;  2JU2 A;  2N98 A;  1VQ8 P;  2DGY A;  1VQL P;  3G29 A;  2K94 A;  2K0D X;  2PEJ A;  3LRY A;  1RNI A;  1CEI A;  2DNW A;  3G71 P;  2FQ2 A;  4PWV B;  2GDX A;  1N8R Q;  2KGC A;  2QEX P;  2CG5 B;  2N5H A;  3P05 A;  5I4T G;  1D1D A;  5HGO A;  3RG2 A;  1AF8 A;  2LML A;  2M8N A;  3DTJ A;  4HKG A;  3B5I A;  5DCK A;  1DV5 A;  2CWO A;  3G21 A;  2JYG A;  1HQB A;  7CEI A;  1E6J P;  3CD6 P;  3G26 A;  2KOD A;  2AFE A;  2EHT A;  1M6E X;  2JYL A;  2ONT A;  2LTE A;  4WYM A;  2GDW A;  2MF4 A;  2JBG A;  3DPH A;  3Q20 A;  3CPW O;  1EMV A;  2FHS C;  2PY8 A;  5HGM A;  2KG6 A;  2JO0 A;  2CNR A;  3G0V A;  2FAD A;  1Q82 Q;  2KW2 A;  2BHV A;  1Q81 Q;  3DS3 A;  5F2O A;  4UHP B;  2M8L A;  3G6E P;  1VQO P;  3I56 P;  1OR5 A;  5HGL A;  2FVA A;  1EIA A;  2L22 A;  1ACP A;  1QVF O;  1VKU A;  2VLP A;  2LIW A;  1A8O A;  3CC2 P;  2VLO A;  2KG8 A;  5BS1 A;  1Z6M A;  3GZM A;  3GKL C;  4MRT C;  1KQS O;  4QKO A;  3DS5 A;  2CGQ A;  4U0F A;  2XV6 A;  2FQ0 A;  1QRJ A;  2JQ4 A;  2KOQ A;  5EW5 E;  1VQK P;  2OTJ P;  4COC A;  1VQ6 P;  1BXI A;  4PH1 A;  2K92 A;  2AF8 A;  1L0H A;  3GJN A;  2MR7 A;  2PEN A;  2MD9 A;  4XFZ A;  3M1M A;  4QNB A;  3CMA P;  2JAZ A;  5F2N A;  2KGD A;  2N50 A;  3GZL A;  2GZI A;  1RO2 A;  2K2Q A;  2LKI A;  4F37 A;  4BPH A;  4H2X C;  3CC4 P;  2GDY A;  4XRO A;  2VLN A;  1MZ8 A;  1YJ9 P;  2LL8 A;  2Z45 A;  4COP A;  2VSQ A;  1FR2 A;  3DS1 A;  1K9M Q;  2GZG A;  2XXM A;  4U0D A;  5HGN A;  3H0D A;  4H2Y C;  4GR6 A;  3CME P;  1YIT P;  2M8P A;  3CCR P;  1M6N A;  1Q86 Q;  2P9X A;  3I55 P;  4IPY A;  5JPA A;  2KR5 A;  1AUM A;  1K73 Q;  3MGE A;  2N6Y A;  2LPK A;  2MY5 A;  2EHS A;  1GPJ A;  5F2K A;  1AYI A;  2E1M A;  1ZMB A;  1VQ4 P;  1VQM P;  3G4S P;  5KP7 B;  3CCL P;  3HYB A;  2L0Q A;  2XZ0 D;  2MR8 A;  2ERH A;  4BPG A;  2L9F A;  2JB0 A;  2N5I A;  1K30 A;  1YJW P;  3H47 A;  4U0C A;  2KWL A;  1NJI Q;  2VLQ A;  4XFX A;  2Z46 A;  2KOO A;  2FVE A;  3DS0 A;  3EJD A;  1VQ7 P;  2KOR A;  2PEI A; 
#chains in the Genus database with same CATH homology
 2QNW A;  1L0H A;  2LOL A;  2FAC A;  3RG2 A;  4PXH B;  1AF8 A;  2JU1 A;  2LML A;  2MR7 A;  4HKG A;  2FVF A;  2K0X A;  1DV5 A;  2AVA A;  2MD9 A;  2X2B A;  1HQB A;  4CA3 A;  2KGD A;  5HV8 A;  2KG9 A;  2N50 A;  3GZL A;  1T8K A;  1X3O A;  1KLP A;  2K2Q A;  2LKI A;  2AFE A;  4BPH A;  2EHT A;  4H2X C;  2CQ8 A;  2GDY A;  2XZ1 C;  2LL8 A;  2LTE A;  1HY8 A;  2GDW A;  2VSQ A;  2K0Y A;  2MF4 A;  5EJD A;  5CZD B;  2MVU A;  4H2Y C;  2FHS C;  2KGE A;  3EJB A;  2FAE A;  2KG6 A;  2CNR A;  2FAD A;  2JGP A;  2AFD A;  4IZ6 A;  1NQ4 A;  2LIU A;  2KW2 A;  2KR5 A;  2M5R A;  3LMO A;  2N6Y A;  1L0I A;  2LPK A;  2MY5 A;  1OR5 A;  2EHS A;  4BPF A;  1F80 D;  2FVA A;  1DNY A;  2L22 A;  1ACP A;  1VKU A;  4H2W C;  2K93 A;  4NEO A;  4DG9 A;  5KP6 B;  5KP7 B;  2PNG A;  2LIW A;  2FQ1 A;  5KP8 B;  3CE7 A;  2KG8 A;  2L0Q A;  2N6Z A;  2XZ0 D;  3GZM A;  3NY7 B;  2MVV A;  5HVC A;  2KOS A;  4MRT C;  2JU2 A;  2N98 A;  2MR8 A;  4BPG A;  2CGQ A;  2K94 A;  2L9F A;  4R0M A;  2L4B A;  2FQ0 A;  2ROQ A;  2JQ4 A;  2N5I A;  2DNW A;  2KOQ A;  2FQ2 A;  4PWV B;  2KWL A;  3EJE A;  2GDX A;  2KOO A;  2KGC A;  2CG5 B;  2FVE A;  2N5H A;  3EJD A;  2K92 A;  2AF8 A;  2KGA A;  2KOR A;  2KOP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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