1ZNVA

How a his-metal finger endonuclease cole7 binds and cleaves dna with a transition metal ion cofactor
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
87
structure length
87
Chain Sequence
MELKNSISDYTEAEFVQLLKEIEKENVAATDDVLDVLLEHFVKITEHPDGTDLIYYPSDNRDDSPEGIVKEIKEWRAANGKPGFKQG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structural analysis and metal-dependent stability and activity studies of the ColE7 endonuclease domain in complex with DNA/Zn2+ or inhibitor/Ni2+
pubmed doi rcsb
molecule tags Hydrolase/protein binding
source organism Escherichia coli str. k12 substr.
molecule keywords Colicin E7 immunity protein
total genus 29
structure length 87
sequence length 87
chains with identical sequence C
ec nomenclature
pdb deposition date 2005-05-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01320 Colicin_Pyocin Colicin immunity protein / pyocin immunity protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.20 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Colicin E immunity protein 1znvA00
1UNKA 1GXHA 1ZNVA 2VLNA 2VLQA 2GZGA 1IMQA 2JAZA 1EMVA 2VLPA 2GZFA 3GJNA 3U43A 2K5XA 2WPTA 4UHPB 1MZ8A 1AYIA 1IMPA 2GZJA 2GZIA 1CEIA 2GZEA 2ERHA 4QKOA 1BXIA 2GYKA 2VLOA 7CEIA 1GXGA 1E0HA 2JB0A 5EW5E 2NO8A 2JBGA 4F37A 2K0DX 3GKLC 1FR2A 1UJZA
chains in the Genus database with same CATH superfamily
2VLNA 2PEQA 3CC7P 2LOLA 2EHTA 2P9XA 1VQ6P 1VHNA 5KP7B 1K73Q 3Q20A 3DS1A 4BPHA 1E0HA 2ROQA 1UJZA 2K0YA 2KOOA 3LRYA 3CCUP 2KOPA 2KOSA 5JPAA 2KGCA 3G0VA 1RO0A 2L4BA 3CCRP 2PEJA 3HZQA 3CCSP 2AVAA 2ERHA 2JYLA 1RNIA 2FQ2A 3CPWO 4MRTC 4H2XC 5BS1A 2L22A 2XV6A 1VQ7P 3NY7B 2BHVA 4PXHB 1DNYA 1EIAA 3H0DA 4XFZA 1F80D 2WPTA 1YI2P 1QRJA 1Z6MA 3G26A 4PH0A 2VSQA 2KOQA 1M74A 2MR7A 1BXIA 5DCKA 3H47A 2N5IA 2PEMA 2CNRA 3GZMA 3VRLC 5HGNA 3G71P 5F2KA 2MR8A 2XZ1C 5CZDB 4UHPB 3P05A 4R0MA 4M0IA 3CXCO 2M8NA 2GZEA 1VQPP 1VQNP 3DS5A 1Q82Q 2EHSA 1YJ9P 2JB0A 4IPYA 2NO8A 3EJEA 4CA3A 2PEIA 5BS2A 2KR5A 4U0EA 1AUMA 2K5XA 4BPGA 3WBHA 1MZ8A 2FAEA 1VQ5P 1IMPA 5KP8B 2LTEA 4QKOA 3CCJP 1W2BO 2KG9A 1ACPA 2EG5A 4XFXA 2AFEA 2LF4A 1VQ9P 1IUQA 1E6JP 5HGMA 5KP6B 3CMEP 1ZMBA 3CC2P 1L0IA 2KGEA 3I56P 2GDWA 2PENA 2LMLA 2QNWA 5F2NA 2EFJA 3CD6P 2VLQA 2GZGA 1X3OA 1EMVA 2VLPA 4QNBA 1HY8A 4U0FA 1VKUA 2LIUA 2GZIA 4U0DA 2OTLP 2OTJP 2M8PA 7CEIA 3G4SP 1BAJA 1YHQP 1KC8Q 3CCLP 1Q7YQ 2PNGA 2BUOA 1ZNVA 2MY5A 1VQMP 2M5RA 1M6NA 2XXMA 2GZFA 1D1DA 4COPA 2PEKA 1K30A 3CCEP 3OW2O 2K92A 2L0QA 2K2QA 4HKGA 2FVFA 2K94A 2KG6A 2L9FA 4XFYA 2JBGA 1KD1Q 1N8RQ 1YITP 1NQ4A 3LMOA 2FVEA 1GXHA 1A8OA 4DG9A 2CGQA 2EIAA 2QEXP 1T8KA 2VLOA 2PEOA 3NTEA 1S72P 2FACA 3I55P 4COCA 3CCQP 2FQ0A 4U0BA 2JAZA 3GJNA 2OARA 2KGAA 4XRQA 3G21A 1K8AQ 5HVCA 4U0CA 4U0AA 2QA4P 4F37A 2K0XA 2L6EA 1YIJP 2DGYA 1YJNP 4BPFA 1IMQA 3CCMP 1HQBA 2Z44A 2AFDA 3EJBA 2JU1A 4PWVB 1KLPA 1M1KQ 2GZJA 2JO0A 1KQSO 2Z46A 2PY8A 2K0DX 1FR2A 3G28A 4WYMA 2KORA 2MVUA 2FHSC 2CQ8A 1GPJA 2KODA 3RG6C 2XT1A 5EW5E 2KGDA 3DS0A 4PH1A 1VQOP 3GKLC 3EJDA 1Q86Q 1VQKP 3DPHA 4NEOA 3CE7A 2K93A 2N6YA 4GR2A 1RO2A 1K9MQ 1AYIA 1AF8A 3RG2A 3DTJA 3HYBA 2GYKA 4H2YC 1M6EX 2CG5B 2GDYA 3MGEA 1EOQA 2CWOA 1VQ8P 2JGPA 3B4QA 4H2WC 5I4TG 2FQ1A 2N6ZA 1QVGO 2LIWA 3DS3A 5F2OA 2FVAA 2E1MA 3H4EA 2M8LA 5EJDA 3G1IA 1JJ2O 4GR6A 2JQ4A 3DS2A 2JYGA 3DS4A 2KW2A 3GZLA 1YJWP 1QVFO 2KWLA 2XZ0D 3G6EP 1VQ4P 2MD9A 2DNWA 1VQLP 1M90Q 3G29A 4XROA 3G1GA 3M1MA 3U43A 2MVVA 2FADA 2LL8A 3CC4P 2N50A 1NJIQ 3CMAP 1GXGA 1A43A 5HGLA 3CCVP 2Z45A 2ONTA 2GDXA 1OR5A 2JU2A 1UNKA 5HGOA 2X2BA 5HV8A 1DV5A 2LKIA 2AF8A 1CEIA 1Q81Q 3B5IA 2N5HA 2N98A 2KG8A 3E2DA 1L0HA 2MF4A 2LPKA 4IZ6A
chains in the Genus database with same CATH topology
1UNKA 1GXHA 1ZNVA 2VLNA 2VLQA 2GZGA 1IMQA 2JAZA 1EMVA 2VLPA 2GZFA 3GJNA 3U43A 2K5XA 2WPTA 4UHPB 1MZ8A 1AYIA 1IMPA 2GZJA 2GZIA 1CEIA 2GZEA 2ERHA 4QKOA 1BXIA 2GYKA 2VLOA 7CEIA 1GXGA 1E0HA 2JB0A 5EW5E 2NO8A 2JBGA 4F37A 2K0DX 3GKLC 1FR2A 1UJZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UNK A;  1GXH A;  1ZNV A;  2VLN A;  2VLQ A;  2GZG A;  1IMQ A;  2JAZ A;  1EMV A;  2VLP A;  2GZF A;  3GJN A;  3U43 A;  2K5X A;  2WPT A;  4UHP B;  1MZ8 A;  1AYI A;  1IMP A;  2GZJ A;  2GZI A;  1CEI A;  2GZE A;  2ERH A;  4QKO A;  1BXI A;  2GYK A;  2VLO A;  7CEI A;  1GXG A;  1E0H A;  2JB0 A;  5EW5 E;  2NO8 A;  2JBG A;  4F37 A;  2K0D X;  3GKL C;  1FR2 A;  1UJZ A; 
#chains in the Genus database with same CATH topology
 2VLN A;  2PEQ A;  3CC7 P;  2LOL A;  2EHT A;  2P9X A;  1VQ6 P;  1VHN A;  5KP7 B;  1K73 Q;  3Q20 A;  3DS1 A;  4BPH A;  1E0H A;  2ROQ A;  1UJZ A;  2K0Y A;  2KOO A;  3LRY A;  3CCU P;  2KOP A;  2KOS A;  5JPA A;  2KGC A;  3G0V A;  1RO0 A;  2L4B A;  3CCR P;  2PEJ A;  3HZQ A;  3CCS P;  2AVA A;  2ERH A;  2JYL A;  1RNI A;  2FQ2 A;  3CPW O;  4MRT C;  4H2X C;  5BS1 A;  2L22 A;  2XV6 A;  1VQ7 P;  3NY7 B;  2BHV A;  4PXH B;  1DNY A;  1EIA A;  3H0D A;  4XFZ A;  1F80 D;  2WPT A;  1YI2 P;  1QRJ A;  1Z6M A;  3G26 A;  4PH0 A;  2VSQ A;  2KOQ A;  1M74 A;  2MR7 A;  1BXI A;  5DCK A;  3H47 A;  2N5I A;  2PEM A;  2CNR A;  3GZM A;  3VRL C;  5HGN A;  3G71 P;  5F2K A;  2MR8 A;  2XZ1 C;  5CZD B;  4UHP B;  3P05 A;  4R0M A;  4M0I A;  3CXC O;  2M8N A;  2GZE A;  1VQP P;  1VQN P;  3DS5 A;  1Q82 Q;  2EHS A;  1YJ9 P;  2JB0 A;  4IPY A;  2NO8 A;  3EJE A;  4CA3 A;  2PEI A;  5BS2 A;  2KR5 A;  4U0E A;  1AUM A;  2K5X A;  4BPG A;  3WBH A;  1MZ8 A;  2FAE A;  1VQ5 P;  1IMP A;  5KP8 B;  2LTE A;  4QKO A;  3CCJ P;  1W2B O;  2KG9 A;  1ACP A;  2EG5 A;  4XFX A;  2AFE A;  2LF4 A;  1VQ9 P;  1IUQ A;  1E6J P;  5HGM A;  5KP6 B;  3CME P;  1ZMB A;  3CC2 P;  1L0I A;  2KGE A;  3I56 P;  2GDW A;  2PEN A;  2LML A;  2QNW A;  5F2N A;  2EFJ A;  3CD6 P;  2VLQ A;  2GZG A;  1X3O A;  1EMV A;  2VLP A;  4QNB A;  1HY8 A;  4U0F A;  1VKU A;  2LIU A;  2GZI A;  4U0D A;  2OTL P;  2OTJ P;  2M8P A;  7CEI A;  3G4S P;  1BAJ A;  1YHQ P;  1KC8 Q;  3CCL P;  1Q7Y Q;  2PNG A;  2BUO A;  1ZNV A;  2MY5 A;  1VQM P;  2M5R A;  1M6N A;  2XXM A;  2GZF A;  1D1D A;  4COP A;  2PEK A;  1K30 A;  3CCE P;  3OW2 O;  2K92 A;  2L0Q A;  2K2Q A;  4HKG A;  2FVF A;  2K94 A;  2KG6 A;  2L9F A;  4XFY A;  2JBG A;  1KD1 Q;  1N8R Q;  1YIT P;  1NQ4 A;  3LMO A;  2FVE A;  1GXH A;  1A8O A;  4DG9 A;  2CGQ A;  2EIA A;  2QEX P;  1T8K A;  2VLO A;  2PEO A;  3NTE A;  1S72 P;  2FAC A;  3I55 P;  4COC A;  3CCQ P;  2FQ0 A;  4U0B A;  2JAZ A;  3GJN A;  2OAR A;  2KGA A;  4XRQ A;  3G21 A;  1K8A Q;  5HVC A;  4U0C A;  4U0A A;  2QA4 P;  4F37 A;  2K0X A;  2L6E A;  1YIJ P;  2DGY A;  1YJN P;  4BPF A;  1IMQ A;  3CCM P;  1HQB A;  2Z44 A;  2AFD A;  3EJB A;  2JU1 A;  4PWV B;  1KLP A;  1M1K Q;  2GZJ A;  2JO0 A;  1KQS O;  2Z46 A;  2PY8 A;  2K0D X;  1FR2 A;  3G28 A;  4WYM A;  2KOR A;  2MVU A;  2FHS C;  2CQ8 A;  1GPJ A;  2KOD A;  3RG6 C;  2XT1 A;  5EW5 E;  2KGD A;  3DS0 A;  4PH1 A;  1VQO P;  3GKL C;  3EJD A;  1Q86 Q;  1VQK P;  3DPH A;  4NEO A;  3CE7 A;  2K93 A;  2N6Y A;  4GR2 A;  1RO2 A;  1K9M Q;  1AYI A;  1AF8 A;  3RG2 A;  3DTJ A;  3HYB A;  2GYK A;  4H2Y C;  1M6E X;  2CG5 B;  2GDY A;  3MGE A;  1EOQ A;  2CWO A;  1VQ8 P;  2JGP A;  3B4Q A;  4H2W C;  5I4T G;  2FQ1 A;  2N6Z A;  1QVG O;  2LIW A;  3DS3 A;  5F2O A;  2FVA A;  2E1M A;  3H4E A;  2M8L A;  5EJD A;  3G1I A;  1JJ2 O;  4GR6 A;  2JQ4 A;  3DS2 A;  2JYG A;  3DS4 A;  2KW2 A;  3GZL A;  1YJW P;  1QVF O;  2KWL A;  2XZ0 D;  3G6E P;  1VQ4 P;  2MD9 A;  2DNW A;  1VQL P;  1M90 Q;  3G29 A;  4XRO A;  3G1G A;  3M1M A;  3U43 A;  2MVV A;  2FAD A;  2LL8 A;  3CC4 P;  2N50 A;  1NJI Q;  3CMA P;  1GXG A;  1A43 A;  5HGL A;  3CCV P;  2Z45 A;  2ONT A;  2GDX A;  1OR5 A;  2JU2 A;  1UNK A;  5HGO A;  2X2B A;  5HV8 A;  1DV5 A;  2LKI A;  2AF8 A;  1CEI A;  1Q81 Q;  3B5I A;  2N5H A;  2N98 A;  2KG8 A;  3E2D A;  1L0H A;  2MF4 A;  2LPK A;  4IZ6 A; 
#chains in the Genus database with same CATH homology
 1UNK A;  1GXH A;  1ZNV A;  2VLN A;  2VLQ A;  2GZG A;  1IMQ A;  2JAZ A;  1EMV A;  2VLP A;  2GZF A;  3GJN A;  3U43 A;  2K5X A;  2WPT A;  4UHP B;  1MZ8 A;  1AYI A;  1IMP A;  2GZJ A;  2GZI A;  1CEI A;  2GZE A;  2ERH A;  4QKO A;  1BXI A;  2GYK A;  2VLO A;  7CEI A;  1GXG A;  1E0H A;  2JB0 A;  5EW5 E;  2NO8 A;  2JBG A;  4F37 A;  2K0D X;  3GKL C;  1FR2 A;  1UJZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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