1ZNVA

How a his-metal finger endonuclease cole7 binds and cleaves dna with a transition metal ion cofactor
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
87
structure length
87
Chain Sequence
MELKNSISDYTEAEFVQLLKEIEKENVAATDDVLDVLLEHFVKITEHPDGTDLIYYPSDNRDDSPEGIVKEIKEWRAANGKPGFKQG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structural analysis and metal-dependent stability and activity studies of the ColE7 endonuclease domain in complex with DNA/Zn2+ or inhibitor/Ni2+
pubmed doi rcsb
molecule tags Hydrolase/protein binding
source organism Escherichia coli str. k12 substr.
molecule keywords Colicin E7 immunity protein
total genus 29
structure length 87
sequence length 87
chains with identical sequence C
ec nomenclature
pdb deposition date 2005-05-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01320 Colicin_Pyocin Colicin immunity protein / pyocin immunity protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.20 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Colicin E immunity protein 1znvA00
1GXGA 2GYKA 2GZIA 2GZGA 3GJNA 4QKOA 1BXIA 1ZNVA 7CEIA 1UNKA 1E0HA 1GXHA 2K0DX 2VLNA 2ERHA 2GZFA 3GKLC 2GZJA 1IMQA 1FR2A 2NO8A 1CEIA 1MZ8A 1IMPA 2JBGA 3U43A 5EW5E 2K5XA 1EMVA 2JAZA 2GZEA 4UHPB 2WPTA 2VLOA 4F37A 2VLQA 1UJZA 2JB0A 2VLPA 1AYIA
chains in the Genus database with same CATH superfamily
3H0DA 2FQ0A 4PH1A 4PXHB 2KGEA 2GZFA 2PEMA 1K8AQ 2N5IA 3G28A 2QNWA 1K30A 1T8KA 4BPGA 3U43A 3DTJA 5HGLA 4U0BA 2FQ1A 1VQ7P 1VQOP 2PNGA 3DS4A 3B5IA 2FVFA 2AFEA 2PEIA 1F80D 3EJDA 1EIAA 5BS2A 5HV8A 2QEXP 3H47A 2XXMA 2MR8A 3DS1A 5I4TG 3CXCO 2K0YA 2EIAA 1QVFO 2PEOA 2PEKA 1HY8A 2GZIA 2MVUA 1VQ6P 2JGPA 2KOOA 3G1IA 2PEQA 2QA4P 3CCSP 1FR2A 2KOQA 3CMAP 1JJ2O 2XT1A 3CCEP 2BHVA 3CMEP 4COCA 1Z6MA 1QRJA 2JYLA 2VLOA 2KG8A 1UJZA 2MVVA 2LOLA 2N6ZA 3DS5A 1AYIA 3NY7B 2LF4A 1VHNA 1AF8A 1GXHA 2XZ0D 1OR5A 2L6EA 2E1MA 4MRTC 2JYGA 4GR6A 4U0CA 3G26A 2KOPA 2CQ8A 2PENA 4HKGA 3CCQP 2L9FA 1ZMBA 4M0IA 4PWVB 2GZJA 3B4QA 1VQ5P 3P05A 1NQ4A 2Z44A 4XFZA 2LMLA 2OTLP 2GDXA 2DNWA 2GYKA 3GJNA 4CA3A 2CNRA 1M6NA 1E0HA 2LL8A 2KW2A 2ERHA 1AUMA 2LIWA 3OW2O 2OTJP 2JO0A 2MF4A 2EG5A 1IMPA 1KC8Q 3CCVP 4COPA 4IZ6A 1NJIQ 3G71P 2Z46A 2BUOA 3G0VA 2K0XA 1E6JP 1D1DA 4QKOA 2VSQA 2AVAA 1YJWP 2X2BA 4BPFA 2EHSA 1UNKA 4XFYA 3CCLP 1VQMP 2KORA 3Q20A 1RNIA 1S72P 1EMVA 1Q7YQ 4DG9A 1M74A 5HGNA 2K2QA 1QVGO 1VQKP 1W2BO 3CC2P 1DNYA 1L0HA 2PEJA 5HGOA 1VQ8P 3DPHA 1YITP 1VQNP 5HGMA 1MZ8A 4R0MA 2L4BA 1A43A 5F2OA 1EOQA 2VLQA 2M8PA 2DGYA 4U0EA 1Q81Q 1KD1Q 2FACA 2GZGA 3M1MA 1BXIA 4U0DA 3CCRP 1A8OA 3DS0A 2CGQA 1N8RQ 1K73Q 1VQLP 3G1GA 4BPHA 2GDYA 2Z45A 2CG5B 2KR5A 1HQBA 2OARA 2JAZA 2KG6A 4U0FA 3CC4P 3RG2A 3I55P 2KWLA 2MR7A 1ZNVA 2M8NA 3EJEA 2VLNA 1K9MQ 2XV6A 3HYBA 2GDWA 3E2DA 4UHPB 2ONTA 3EJBA 2VLPA 3G21A 7CEIA 4PH0A 2P9XA 4H2YC 2LKIA 4XFXA 3DS3A 5EJDA 4XRQA 2AF8A 1M90Q 4QNBA 2N6YA 2K93A 2NO8A 3LMOA 3WBHA 1X3OA 2K5XA 3CCJP 4NEOA 3MGEA 3H4EA 4H2WC 4WYMA 3DS2A 3CE7A 1KLPA 4IPYA 3VRLC 2N5HA 5KP6B 1VQ9P 4U0AA 2LTEA 3CD6P 3G4SP 2K92A 2FVEA 3CPWO 3RG6C 2GZEA 2PY8A 2ROQA 5F2NA 4H2XC 2N98A 3CCUP 1M1KQ 1YJ9P 1VQ4P 2EFJA 2KOSA 2K0DX 2MY5A 2JU1A 1IMQA 2AFDA 2LPKA 3NTEA 1RO0A 2FADA 3I56P 3GZLA 4F37A 1VQPP 3CC7P 5DCKA 1GXGA 2KGCA 1YJNP 3CCMP 2M8LA 5CZDB 2FHSC 1YI2P 4GR2A 2EHTA 2JU2A 1CEIA 2N50A 3GZMA 1BAJA 2L0QA 1L0IA 2XZ1C 1Q82Q 2K94A 1RO2A 1GPJA 2CWOA 1VKUA 2KODA 1IUQA 5F2KA 2L22A 5HVCA 2JBGA 2FAEA 1KQSO 1ACPA 5KP7B 2MD9A 2WPTA 3HZQA 1Q86Q 1M6EX 5BS1A 1YIJP 2KGDA 5KP8B 3LRYA 5JPAA 2FVAA 2FQ2A 2LIUA 1DV5A 2KGAA 3GKLC 4XROA 3G29A 2M5RA 5EW5E 2KG9A 2JQ4A 1YHQP 3G6EP 2JB0A
chains in the Genus database with same CATH topology
1GXGA 2GYKA 2GZIA 2GZGA 3GJNA 4QKOA 1BXIA 1ZNVA 7CEIA 1UNKA 1E0HA 1GXHA 2K0DX 2VLNA 2ERHA 2GZFA 3GKLC 2GZJA 1IMQA 1FR2A 2NO8A 1CEIA 1MZ8A 1IMPA 2JBGA 3U43A 5EW5E 2K5XA 1EMVA 2JAZA 2GZEA 4UHPB 2WPTA 2VLOA 4F37A 2VLQA 1UJZA 2JB0A 2VLPA 1AYIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GXG A;  2GYK A;  2GZI A;  2GZG A;  3GJN A;  4QKO A;  1BXI A;  1ZNV A;  7CEI A;  1UNK A;  1E0H A;  1GXH A;  2K0D X;  2VLN A;  2ERH A;  2GZF A;  3GKL C;  2GZJ A;  1IMQ A;  1FR2 A;  2NO8 A;  1CEI A;  1MZ8 A;  1IMP A;  2JBG A;  3U43 A;  5EW5 E;  2K5X A;  1EMV A;  2JAZ A;  2GZE A;  4UHP B;  2WPT A;  2VLO A;  4F37 A;  2VLQ A;  1UJZ A;  2JB0 A;  2VLP A;  1AYI A; 
#chains in the Genus database with same CATH topology
 3H0D A;  2FQ0 A;  4PH1 A;  4PXH B;  2KGE A;  2GZF A;  2PEM A;  1K8A Q;  2N5I A;  3G28 A;  2QNW A;  1K30 A;  1T8K A;  4BPG A;  3U43 A;  3DTJ A;  5HGL A;  4U0B A;  2FQ1 A;  1VQ7 P;  1VQO P;  2PNG A;  3DS4 A;  3B5I A;  2FVF A;  2AFE A;  2PEI A;  1F80 D;  3EJD A;  1EIA A;  5BS2 A;  5HV8 A;  2QEX P;  3H47 A;  2XXM A;  2MR8 A;  3DS1 A;  5I4T G;  3CXC O;  2K0Y A;  2EIA A;  1QVF O;  2PEO A;  2PEK A;  1HY8 A;  2GZI A;  2MVU A;  1VQ6 P;  2JGP A;  2KOO A;  3G1I A;  2PEQ A;  2QA4 P;  3CCS P;  1FR2 A;  2KOQ A;  3CMA P;  1JJ2 O;  2XT1 A;  3CCE P;  2BHV A;  3CME P;  4COC A;  1Z6M A;  1QRJ A;  2JYL A;  2VLO A;  2KG8 A;  1UJZ A;  2MVV A;  2LOL A;  2N6Z A;  3DS5 A;  1AYI A;  3NY7 B;  2LF4 A;  1VHN A;  1AF8 A;  1GXH A;  2XZ0 D;  1OR5 A;  2L6E A;  2E1M A;  4MRT C;  2JYG A;  4GR6 A;  4U0C A;  3G26 A;  2KOP A;  2CQ8 A;  2PEN A;  4HKG A;  3CCQ P;  2L9F A;  1ZMB A;  4M0I A;  4PWV B;  2GZJ A;  3B4Q A;  1VQ5 P;  3P05 A;  1NQ4 A;  2Z44 A;  4XFZ A;  2LML A;  2OTL P;  2GDX A;  2DNW A;  2GYK A;  3GJN A;  4CA3 A;  2CNR A;  1M6N A;  1E0H A;  2LL8 A;  2KW2 A;  2ERH A;  1AUM A;  2LIW A;  3OW2 O;  2OTJ P;  2JO0 A;  2MF4 A;  2EG5 A;  1IMP A;  1KC8 Q;  3CCV P;  4COP A;  4IZ6 A;  1NJI Q;  3G71 P;  2Z46 A;  2BUO A;  3G0V A;  2K0X A;  1E6J P;  1D1D A;  4QKO A;  2VSQ A;  2AVA A;  1YJW P;  2X2B A;  4BPF A;  2EHS A;  1UNK A;  4XFY A;  3CCL P;  1VQM P;  2KOR A;  3Q20 A;  1RNI A;  1S72 P;  1EMV A;  1Q7Y Q;  4DG9 A;  1M74 A;  5HGN A;  2K2Q A;  1QVG O;  1VQK P;  1W2B O;  3CC2 P;  1DNY A;  1L0H A;  2PEJ A;  5HGO A;  1VQ8 P;  3DPH A;  1YIT P;  1VQN P;  5HGM A;  1MZ8 A;  4R0M A;  2L4B A;  1A43 A;  5F2O A;  1EOQ A;  2VLQ A;  2M8P A;  2DGY A;  4U0E A;  1Q81 Q;  1KD1 Q;  2FAC A;  2GZG A;  3M1M A;  1BXI A;  4U0D A;  3CCR P;  1A8O A;  3DS0 A;  2CGQ A;  1N8R Q;  1K73 Q;  1VQL P;  3G1G A;  4BPH A;  2GDY A;  2Z45 A;  2CG5 B;  2KR5 A;  1HQB A;  2OAR A;  2JAZ A;  2KG6 A;  4U0F A;  3CC4 P;  3RG2 A;  3I55 P;  2KWL A;  2MR7 A;  1ZNV A;  2M8N A;  3EJE A;  2VLN A;  1K9M Q;  2XV6 A;  3HYB A;  2GDW A;  3E2D A;  4UHP B;  2ONT A;  3EJB A;  2VLP A;  3G21 A;  7CEI A;  4PH0 A;  2P9X A;  4H2Y C;  2LKI A;  4XFX A;  3DS3 A;  5EJD A;  4XRQ A;  2AF8 A;  1M90 Q;  4QNB A;  2N6Y A;  2K93 A;  2NO8 A;  3LMO A;  3WBH A;  1X3O A;  2K5X A;  3CCJ P;  4NEO A;  3MGE A;  3H4E A;  4H2W C;  4WYM A;  3DS2 A;  3CE7 A;  1KLP A;  4IPY A;  3VRL C;  2N5H A;  5KP6 B;  1VQ9 P;  4U0A A;  2LTE A;  3CD6 P;  3G4S P;  2K92 A;  2FVE A;  3CPW O;  3RG6 C;  2GZE A;  2PY8 A;  2ROQ A;  5F2N A;  4H2X C;  2N98 A;  3CCU P;  1M1K Q;  1YJ9 P;  1VQ4 P;  2EFJ A;  2KOS A;  2K0D X;  2MY5 A;  2JU1 A;  1IMQ A;  2AFD A;  2LPK A;  3NTE A;  1RO0 A;  2FAD A;  3I56 P;  3GZL A;  4F37 A;  1VQP P;  3CC7 P;  5DCK A;  1GXG A;  2KGC A;  1YJN P;  3CCM P;  2M8L A;  5CZD B;  2FHS C;  1YI2 P;  4GR2 A;  2EHT A;  2JU2 A;  1CEI A;  2N50 A;  3GZM A;  1BAJ A;  2L0Q A;  1L0I A;  2XZ1 C;  1Q82 Q;  2K94 A;  1RO2 A;  1GPJ A;  2CWO A;  1VKU A;  2KOD A;  1IUQ A;  5F2K A;  2L22 A;  5HVC A;  2JBG A;  2FAE A;  1KQS O;  1ACP A;  5KP7 B;  2MD9 A;  2WPT A;  3HZQ A;  1Q86 Q;  1M6E X;  5BS1 A;  1YIJ P;  2KGD A;  5KP8 B;  3LRY A;  5JPA A;  2FVA A;  2FQ2 A;  2LIU A;  1DV5 A;  2KGA A;  3GKL C;  4XRO A;  3G29 A;  2M5R A;  5EW5 E;  2KG9 A;  2JQ4 A;  1YHQ P;  3G6E P;  2JB0 A; 
#chains in the Genus database with same CATH homology
 1GXG A;  2GYK A;  2GZI A;  2GZG A;  3GJN A;  4QKO A;  1BXI A;  1ZNV A;  7CEI A;  1UNK A;  1E0H A;  1GXH A;  2K0D X;  2VLN A;  2ERH A;  2GZF A;  3GKL C;  2GZJ A;  1IMQ A;  1FR2 A;  2NO8 A;  1CEI A;  1MZ8 A;  1IMP A;  2JBG A;  3U43 A;  5EW5 E;  2K5X A;  1EMV A;  2JAZ A;  2GZE A;  4UHP B;  2WPT A;  2VLO A;  4F37 A;  2VLQ A;  1UJZ A;  2JB0 A;  2VLP A;  1AYI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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