1GXGA

Non-cognate protein-protein interactions: the nmr structure of the colicin e8 inhibitor protein im8 and its interaction with the dnase domain of colicin e9
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
85
structure length
85
Chain Sequence
MELKNSISDYTETEFKKIIEDIINCEGDEKKQDDNLEHFISVTEHPSGSDLIYYPEGNNDGSPEAVIKEIKEWRAANGKSGFKQG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Non-Cognate Protein-Protein Interaction: The NMR Structure of the Colicin E8 Inhibitor Protein Im8 and its Interaction with the DNase Domain of Colicin E9
rcsb
molecule tags Inhibitor
source organism Escherichia coli
molecule keywords COLICIN E8 IMMUNITY PROTEIN
total genus 36
structure length 85
sequence length 85
ec nomenclature
pdb deposition date 2002-04-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01320 Colicin_Pyocin Colicin immunity protein / pyocin immunity protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.20 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Colicin E immunity protein 1gxgA00
2GZFA 2K5XA 1BXIA 2GZEA 1IMPA 1ZNVA 1GXGA 3GJNA 3GKLC 2GYKA 1FR2A 7CEIA 1IMQA 2GZJA 2K0DX 2VLPA 1GXHA 1MZ8A 1EMVA 2GZIA 1UJZA 2VLOA 2ERHA 4F37A 2GZGA 1CEIA 2VLNA 5EW5E 1E0HA 2JBGA 3U43A 2VLQA 1AYIA 1UNKA 2JB0A 4UHPB 4QKOA 2WPTA 2JAZA 2NO8A
chains in the Genus database with same CATH superfamily
2JQ4A 2XXMA 2K5XA 4COPA 2LIWA 3EJEA 3HYBA 1IUQA 2OTLP 4U0BA 5HVCA 1VQPP 2BUOA 5HV8A 2JGPA 2N5HA 2WPTA 2KGAA 1S72P 1IMPA 1ZNVA 1YI2P 3GKLC 1YIJP 5DCKA 4BPHA 1EMVA 2X2BA 2L22A 4GR2A 2EHSA 2FVFA 3CC2P 3CCUP 1VQ5P 1RNIA 1KD1Q 2XZ0D 1VQ4P 2L4BA 2VSQA 5F2KA 1YJWP 2LPKA 1Q82Q 3RG6C 2GZIA 2KW2A 3G26A 2FQ2A 2EFJA 3H47A 1VHNA 1AUMA 2GZFA 4H2XC 1VQ6P 4COCA 3OW2O 3G1IA 2K93A 3G1GA 3CCMP 4U0FA 1GXHA 1MZ8A 2L0QA 2VLOA 2JBGA 2JYLA 2XZ1C 1JJ2O 2PEJA 1GPJA 2FQ1A 2LKIA 1UNKA 3GZLA 2MVUA 2EG5A 2KORA 3CCEP 1M90Q 2KWLA 1FR2A 2CNRA 5HGOA 3NTEA 1Q7YQ 2GDWA 1UJZA 4XFXA 1VKUA 5F2NA 1HQBA 3CCVP 2QA4P 4BPFA 3CMEP 4MRTC 2BHVA 2K0XA 2JU2A 2GDXA 2KODA 4PH1A 4GR6A 1NQ4A 2N98A 2ONTA 1VQKP 1RO2A 2FAEA 2K0DX 3G29A 3P05A 2PEKA 2GZGA 2VLNA 3CE7A 2KOSA 1VQMP 3EJDA 2JB0A 3G21A 1VQLP 4NEOA 1EIAA 3E2DA 2JAZA 3CC7P 1E0HA 1KC8Q 2JU1A 4R0MA 2KG9A 1OR5A 2N5IA 5KP6B 4CA3A 2XT1A 2JYGA 3DS1A 4F37A 2K92A 1A8OA 3EJBA 4XFYA 5HGMA 2OTJP 2GZEA 2QEXP 4U0AA 2N6YA 2AFDA 1IMQA 3Q20A 2VLPA 1QVFO 2MF4A 2P9XA 3G28A 2PNGA 2PEOA 4QKOA 5KP7B 4H2WC 2M8LA 2M5RA 5BS1A 3CCQP 1GXGA 2GYKA 3MGEA 4BPGA 5F2OA 3CC4P 3DS5A 3GZMA 3CD6P 1X3OA 1M6NA 3G6EP 4UHPB 3G0VA 2KR5A 3DS2A 3CCRP 2FHSC 2OARA 4QNBA 1HY8A 1K8AQ 2FACA 1K30A 1YJNP 2M8PA 5CZDB 1VQNP 1M6EX 2Z45A 2CWOA 3LRYA 1VQ7P 5BS2A 2KGDA 4XRQA 2KOOA 2EIAA 2LOLA 1RO0A 1DNYA 4PXHB 2CGQA 1K73Q 4XROA 2GDYA 4DG9A 1YJ9P 1E6JP 1YITP 3VRLC 5EW5E 3U43A 2FADA 2PEIA 2KOPA 3HZQA 4U0CA 2QNWA 2FVAA 2ROQA 2K94A 3DS4A 2AF8A 4IPYA 3GJNA 3WBHA 4M0IA 2LTEA 3CXCO 1Q81Q 1DV5A 2LF4A 3H4EA 4PWVB 2MVVA 2E1MA 1ZMBA 1Z6MA 3RG2A 3B4QA 1YHQP 3CMAP 2CG5B 2FVEA 5HGLA 5HGNA 3I56P 2K0YA 2GZJA 2AFEA 2KGCA 2PEMA 2DNWA 2DGYA 1AF8A 2ERHA 2M8NA 1AYIA 2N50A 3CPWO 1KQSO 1QVGO 2NO8A 2KG6A 2K2QA 2PENA 3NY7B 3CCLP 1D1DA 1L0IA 4H2YC 1L0HA 4U0DA 5KP8B 4HKGA 1K9MQ 2L9FA 1QRJA 4WYMA 2EHTA 2MD9A 1VQ8P 3G71P 2CQ8A 1EOQA 3M1MA 1N8RQ 2LL8A 1F80D 2PY8A 1M74A 4U0EA 3I55P 1VQ9P 1BAJA 2JO0A 5EJDA 1M1KQ 2MY5A 2KGEA 1VQOP 2AVAA 1T8KA 1W2BO 7CEIA 2Z46A 3B5IA 2L6EA 3CCSP 2LIUA 5JPAA 2VLQA 4IZ6A 2Z44A 2FQ0A 2N6ZA 1Q86Q 5I4TG 2PEQA 3CCJP 1ACPA 2KOQA 1BXIA 3DPHA 4PH0A 2KG8A 2MR7A 2LMLA 2MR8A 1A43A 3LMOA 1NJIQ 1CEIA 3H0DA 1KLPA 3DTJA 2XV6A 3DS0A 4XFZA 3G4SP 3DS3A
chains in the Genus database with same CATH topology
2GZFA 2K5XA 1BXIA 2GZEA 1IMPA 1ZNVA 1GXGA 3GJNA 3GKLC 2GYKA 1FR2A 7CEIA 1IMQA 2GZJA 2K0DX 2VLPA 1GXHA 1MZ8A 1EMVA 2GZIA 1UJZA 2VLOA 2ERHA 4F37A 2GZGA 1CEIA 2VLNA 5EW5E 1E0HA 2JBGA 3U43A 2VLQA 1AYIA 1UNKA 2JB0A 4UHPB 4QKOA 2WPTA 2JAZA 2NO8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GZF A;  2K5X A;  1BXI A;  2GZE A;  1IMP A;  1ZNV A;  1GXG A;  3GJN A;  3GKL C;  2GYK A;  1FR2 A;  7CEI A;  1IMQ A;  2GZJ A;  2K0D X;  2VLP A;  1GXH A;  1MZ8 A;  1EMV A;  2GZI A;  1UJZ A;  2VLO A;  2ERH A;  4F37 A;  2GZG A;  1CEI A;  2VLN A;  5EW5 E;  1E0H A;  2JBG A;  3U43 A;  2VLQ A;  1AYI A;  1UNK A;  2JB0 A;  4UHP B;  4QKO A;  2WPT A;  2JAZ A;  2NO8 A; 
#chains in the Genus database with same CATH topology
 2JQ4 A;  2XXM A;  2K5X A;  4COP A;  2LIW A;  3EJE A;  3HYB A;  1IUQ A;  2OTL P;  4U0B A;  5HVC A;  1VQP P;  2BUO A;  5HV8 A;  2JGP A;  2N5H A;  2WPT A;  2KGA A;  1S72 P;  1IMP A;  1ZNV A;  1YI2 P;  3GKL C;  1YIJ P;  5DCK A;  4BPH A;  1EMV A;  2X2B A;  2L22 A;  4GR2 A;  2EHS A;  2FVF A;  3CC2 P;  3CCU P;  1VQ5 P;  1RNI A;  1KD1 Q;  2XZ0 D;  1VQ4 P;  2L4B A;  2VSQ A;  5F2K A;  1YJW P;  2LPK A;  1Q82 Q;  3RG6 C;  2GZI A;  2KW2 A;  3G26 A;  2FQ2 A;  2EFJ A;  3H47 A;  1VHN A;  1AUM A;  2GZF A;  4H2X C;  1VQ6 P;  4COC A;  3OW2 O;  3G1I A;  2K93 A;  3G1G A;  3CCM P;  4U0F A;  1GXH A;  1MZ8 A;  2L0Q A;  2VLO A;  2JBG A;  2JYL A;  2XZ1 C;  1JJ2 O;  2PEJ A;  1GPJ A;  2FQ1 A;  2LKI A;  1UNK A;  3GZL A;  2MVU A;  2EG5 A;  2KOR A;  3CCE P;  1M90 Q;  2KWL A;  1FR2 A;  2CNR A;  5HGO A;  3NTE A;  1Q7Y Q;  2GDW A;  1UJZ A;  4XFX A;  1VKU A;  5F2N A;  1HQB A;  3CCV P;  2QA4 P;  4BPF A;  3CME P;  4MRT C;  2BHV A;  2K0X A;  2JU2 A;  2GDX A;  2KOD A;  4PH1 A;  4GR6 A;  1NQ4 A;  2N98 A;  2ONT A;  1VQK P;  1RO2 A;  2FAE A;  2K0D X;  3G29 A;  3P05 A;  2PEK A;  2GZG A;  2VLN A;  3CE7 A;  2KOS A;  1VQM P;  3EJD A;  2JB0 A;  3G21 A;  1VQL P;  4NEO A;  1EIA A;  3E2D A;  2JAZ A;  3CC7 P;  1E0H A;  1KC8 Q;  2JU1 A;  4R0M A;  2KG9 A;  1OR5 A;  2N5I A;  5KP6 B;  4CA3 A;  2XT1 A;  2JYG A;  3DS1 A;  4F37 A;  2K92 A;  1A8O A;  3EJB A;  4XFY A;  5HGM A;  2OTJ P;  2GZE A;  2QEX P;  4U0A A;  2N6Y A;  2AFD A;  1IMQ A;  3Q20 A;  2VLP A;  1QVF O;  2MF4 A;  2P9X A;  3G28 A;  2PNG A;  2PEO A;  4QKO A;  5KP7 B;  4H2W C;  2M8L A;  2M5R A;  5BS1 A;  3CCQ P;  1GXG A;  2GYK A;  3MGE A;  4BPG A;  5F2O A;  3CC4 P;  3DS5 A;  3GZM A;  3CD6 P;  1X3O A;  1M6N A;  3G6E P;  4UHP B;  3G0V A;  2KR5 A;  3DS2 A;  3CCR P;  2FHS C;  2OAR A;  4QNB A;  1HY8 A;  1K8A Q;  2FAC A;  1K30 A;  1YJN P;  2M8P A;  5CZD B;  1VQN P;  1M6E X;  2Z45 A;  2CWO A;  3LRY A;  1VQ7 P;  5BS2 A;  2KGD A;  4XRQ A;  2KOO A;  2EIA A;  2LOL A;  1RO0 A;  1DNY A;  4PXH B;  2CGQ A;  1K73 Q;  4XRO A;  2GDY A;  4DG9 A;  1YJ9 P;  1E6J P;  1YIT P;  3VRL C;  5EW5 E;  3U43 A;  2FAD A;  2PEI A;  2KOP A;  3HZQ A;  4U0C A;  2QNW A;  2FVA A;  2ROQ A;  2K94 A;  3DS4 A;  2AF8 A;  4IPY A;  3GJN A;  3WBH A;  4M0I A;  2LTE A;  3CXC O;  1Q81 Q;  1DV5 A;  2LF4 A;  3H4E A;  4PWV B;  2MVV A;  2E1M A;  1ZMB A;  1Z6M A;  3RG2 A;  3B4Q A;  1YHQ P;  3CMA P;  2CG5 B;  2FVE A;  5HGL A;  5HGN A;  3I56 P;  2K0Y A;  2GZJ A;  2AFE A;  2KGC A;  2PEM A;  2DNW A;  2DGY A;  1AF8 A;  2ERH A;  2M8N A;  1AYI A;  2N50 A;  3CPW O;  1KQS O;  1QVG O;  2NO8 A;  2KG6 A;  2K2Q A;  2PEN A;  3NY7 B;  3CCL P;  1D1D A;  1L0I A;  4H2Y C;  1L0H A;  4U0D A;  5KP8 B;  4HKG A;  1K9M Q;  2L9F A;  1QRJ A;  4WYM A;  2EHT A;  2MD9 A;  1VQ8 P;  3G71 P;  2CQ8 A;  1EOQ A;  3M1M A;  1N8R Q;  2LL8 A;  1F80 D;  2PY8 A;  1M74 A;  4U0E A;  3I55 P;  1VQ9 P;  1BAJ A;  2JO0 A;  5EJD A;  1M1K Q;  2MY5 A;  2KGE A;  1VQO P;  2AVA A;  1T8K A;  1W2B O;  7CEI A;  2Z46 A;  3B5I A;  2L6E A;  3CCS P;  2LIU A;  5JPA A;  2VLQ A;  4IZ6 A;  2Z44 A;  2FQ0 A;  2N6Z A;  1Q86 Q;  5I4T G;  2PEQ A;  3CCJ P;  1ACP A;  2KOQ A;  1BXI A;  3DPH A;  4PH0 A;  2KG8 A;  2MR7 A;  2LML A;  2MR8 A;  1A43 A;  3LMO A;  1NJI Q;  1CEI A;  3H0D A;  1KLP A;  3DTJ A;  2XV6 A;  3DS0 A;  4XFZ A;  3G4S P;  3DS3 A; 
#chains in the Genus database with same CATH homology
 2GZF A;  2K5X A;  1BXI A;  2GZE A;  1IMP A;  1ZNV A;  1GXG A;  3GJN A;  3GKL C;  2GYK A;  1FR2 A;  7CEI A;  1IMQ A;  2GZJ A;  2K0D X;  2VLP A;  1GXH A;  1MZ8 A;  1EMV A;  2GZI A;  1UJZ A;  2VLO A;  2ERH A;  4F37 A;  2GZG A;  1CEI A;  2VLN A;  5EW5 E;  1E0H A;  2JBG A;  3U43 A;  2VLQ A;  1AYI A;  1UNK A;  2JB0 A;  4UHP B;  4QKO A;  2WPT A;  2JAZ A;  2NO8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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