1MZ8A

Crystal structures of the nuclease domain of cole7/im7 in complex with a phosphate ion and a zinc ion
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
87
structure length
87
Chain Sequence
MELKNSISDYTEAEFVQLLKEIEKENVAATDDVLDVLLEHFVKITEHPDGTDLIYYPSDNRDDSPEGIVKEIKEWRAANGKPGFKQG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Metal ions and phosphate binding in the H-N-H motif: crystal structures of the nuclease domain of ColE7/Im7 in complex with a phosphate ion and different divalent metal ions
pubmed doi rcsb
molecule tags Toxin,hydrolase/protein binding
source organism Escherichia coli
molecule keywords Colicin E7 immunity protein
total genus 30
structure length 87
sequence length 87
chains with identical sequence C
ec nomenclature
pdb deposition date 2002-10-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01320 Colicin_Pyocin Colicin immunity protein / pyocin immunity protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.20 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Colicin E immunity protein 1mz8A00
1FR2A 1BXIA 1IMQA 2GYKA 2GZJA 2JAZA 2GZGA 3GJNA 1UNKA 1MZ8A 1AYIA 2VLQA 1GXHA 2VLOA 1GXGA 1E0HA 2ERHA 4F37A 2VLPA 2WPTA 2GZFA 2K5XA 2JBGA 1IMPA 2NO8A 3GKLC 4UHPB 5EW5E 1EMVA 2JB0A 2VLNA 2GZIA 1CEIA 2GZEA 2K0DX 4QKOA 7CEIA 1ZNVA 3U43A 1UJZA
chains in the Genus database with same CATH superfamily
5BS2A 5CZDB 2MR8A 2VLQA 1VQKP 2AF8A 5F2NA 2GDXA 3CXCO 3CC2P 1E6JP 2AFDA 4M0IA 5HV8A 2K0XA 2XXMA 2L9FA 3G1IA 1HY8A 3G26A 1M90Q 1N8RQ 1VQ6P 2MF4A 2LIWA 1ACPA 1Z6MA 1VQ4P 2EIAA 1YITP 5I4TG 2LF4A 1M1KQ 2JGPA 3EJDA 1VQNP 4F37A 3G29A 4R0MA 1YJ9P 2L4BA 3GZLA 5F2OA 2MVUA 2GZIA 2MVVA 2P9XA 1YJNP 2DGYA 4H2XC 4BPGA 4XFYA 2CG5B 2M8NA 5JPAA 1GXHA 2KWLA 2PENA 2L6EA 3Q20A 2K5XA 1VQMP 1NJIQ 2N5HA 3GKLC 1Q7YQ 1KQSO 4BPFA 1EMVA 4U0BA 2DNWA 1ZNVA 4U0CA 3G71P 4GR2A 2KOOA 2GYKA 2EFJA 4XRQA 3DTJA 2VLOA 3CCUP 3I55P 2GZFA 1X3OA 2AFEA 1K30A 3DPHA 2FADA 1S72P 3CC4P 2KOPA 2LOLA 2Z44A 1L0HA 2K0DX 2LL8A 4QKOA 4U0FA 1VQPP 2K0YA 1T8KA 2M8LA 3EJBA 1IUQA 2EHSA 3G21A 2KORA 2XV6A 3G0VA 2NO8A 1VQ8P 2LKIA 2PEJA 4PWVB 2KW2A 3CCJP 1UJZA 1KD1Q 2GZJA 4XROA 2EG5A 4DG9A 4QNBA 2JYGA 1KLPA 3CPWO 3E2DA 3OW2O 2FQ1A 2PEQA 2XZ0D 1DNYA 3CCLP 2M8PA 3CCMP 5HGLA 2ONTA 1QVFO 1K8AQ 3H0DA 1MZ8A 2M5RA 2FVEA 5F2KA 3CCQP 2E1MA 4U0EA 4PXHB 1VQ7P 2MY5A 1F80D 1KC8Q 4GR6A 2JB0A 2PY8A 3NY7B 1CEIA 1QRJA 2N6ZA 2QNWA 3CCEP 2LIUA 3B5IA 3GJNA 1W2BO 1RNIA 1AYIA 1Q86Q 2N5IA 3I56P 2FACA 2KG6A 4MRTC 1IMPA 2LMLA 3EJEA 1A8OA 4CA3A 3LRYA 2LTEA 1QVGO 2OTLP 4IPYA 2FQ0A 3NTEA 1GXGA 3DS4A 2PNGA 2KOSA 5EJDA 2CQ8A 4U0DA 3DS2A 1YI2P 3B4QA 1VQOP 2JYLA 2AVAA 2BHVA 2GZGA 2JAZA 4XFZA 1GPJA 5HGMA 1BAJA 2ERHA 2VLPA 2KGCA 4WYMA 3HYBA 3MGEA 2FAEA 4HKGA 2KGAA 2OARA 4COPA 2KGDA 3RG2A 2JO0A 1BXIA 4COCA 3DS3A 2EHTA 1JJ2O 1L0IA 1M6NA 4H2WC 1E0HA 2N98A 1YJWP 4XFXA 5KP8B 2PEIA 4NEOA 4PH1A 2FHSC 3CCSP 5HVCA 5DCKA 1DV5A 3CMAP 1IMQA 1Q81Q 1VQLP 5HGNA 2JQ4A 3H47A 2PEKA 1Q82Q 2VSQA 2CWOA 3HZQA 1M6EX 1AUMA 2OTJP 1YHQP 1NQ4A 2FVFA 1K73Q 2GZEA 1ZMBA 2K94A 3CC7P 1HQBA 2K93A 2KODA 2X2BA 2KR5A 3CE7A 2KGEA 3RG6C 1EOQA 5BS1A 3G28A 3M1MA 3LMOA 3DS0A 5KP6B 5HGOA 1AF8A 3G1GA 4BPHA 3H4EA 2JU2A 2XZ1C 4UHPB 2QEXP 1YIJP 2N6YA 2PEOA 4PH0A 1FR2A 1M74A 2ROQA 3GZMA 5KP7B 2KG8A 2QA4P 2LPKA 2K2QA 1RO0A 2FVAA 2XT1A 3DS1A 4IZ6A 3VRLC 2CGQA 2N50A 1VQ5P 1VQ9P 3DS5A 2K92A 2Z46A 2L0QA 2MD9A 1UNKA 1D1DA 2GDYA 1VKUA 4U0AA 2FQ2A 2KOQA 2WPTA 3CD6P 4H2YC 3G6EP 2JBGA 2KG9A 3CMEP 2MR7A 1RO2A 5EW5E 2VLNA 3G4SP 1OR5A 7CEIA 3U43A 2BUOA 3CCVP 2GDWA 2Z45A 2CNRA 2PEMA 3WBHA 3CCRP 1K9MQ 1VHNA 1EIAA 2L22A 3P05A 2JU1A 1A43A
chains in the Genus database with same CATH topology
1FR2A 1BXIA 1IMQA 2GYKA 2GZJA 2JAZA 2GZGA 3GJNA 1UNKA 1MZ8A 1AYIA 2VLQA 1GXHA 2VLOA 1GXGA 1E0HA 2ERHA 4F37A 2VLPA 2WPTA 2GZFA 2K5XA 2JBGA 1IMPA 2NO8A 3GKLC 4UHPB 5EW5E 1EMVA 2JB0A 2VLNA 2GZIA 1CEIA 2GZEA 2K0DX 4QKOA 7CEIA 1ZNVA 3U43A 1UJZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FR2 A;  1BXI A;  1IMQ A;  2GYK A;  2GZJ A;  2JAZ A;  2GZG A;  3GJN A;  1UNK A;  1MZ8 A;  1AYI A;  2VLQ A;  1GXH A;  2VLO A;  1GXG A;  1E0H A;  2ERH A;  4F37 A;  2VLP A;  2WPT A;  2GZF A;  2K5X A;  2JBG A;  1IMP A;  2NO8 A;  3GKL C;  4UHP B;  5EW5 E;  1EMV A;  2JB0 A;  2VLN A;  2GZI A;  1CEI A;  2GZE A;  2K0D X;  4QKO A;  7CEI A;  1ZNV A;  3U43 A;  1UJZ A; 
#chains in the Genus database with same CATH topology
 5BS2 A;  5CZD B;  2MR8 A;  2VLQ A;  1VQK P;  2AF8 A;  5F2N A;  2GDX A;  3CXC O;  3CC2 P;  1E6J P;  2AFD A;  4M0I A;  5HV8 A;  2K0X A;  2XXM A;  2L9F A;  3G1I A;  1HY8 A;  3G26 A;  1M90 Q;  1N8R Q;  1VQ6 P;  2MF4 A;  2LIW A;  1ACP A;  1Z6M A;  1VQ4 P;  2EIA A;  1YIT P;  5I4T G;  2LF4 A;  1M1K Q;  2JGP A;  3EJD A;  1VQN P;  4F37 A;  3G29 A;  4R0M A;  1YJ9 P;  2L4B A;  3GZL A;  5F2O A;  2MVU A;  2GZI A;  2MVV A;  2P9X A;  1YJN P;  2DGY A;  4H2X C;  4BPG A;  4XFY A;  2CG5 B;  2M8N A;  5JPA A;  1GXH A;  2KWL A;  2PEN A;  2L6E A;  3Q20 A;  2K5X A;  1VQM P;  1NJI Q;  2N5H A;  3GKL C;  1Q7Y Q;  1KQS O;  4BPF A;  1EMV A;  4U0B A;  2DNW A;  1ZNV A;  4U0C A;  3G71 P;  4GR2 A;  2KOO A;  2GYK A;  2EFJ A;  4XRQ A;  3DTJ A;  2VLO A;  3CCU P;  3I55 P;  2GZF A;  1X3O A;  2AFE A;  1K30 A;  3DPH A;  2FAD A;  1S72 P;  3CC4 P;  2KOP A;  2LOL A;  2Z44 A;  1L0H A;  2K0D X;  2LL8 A;  4QKO A;  4U0F A;  1VQP P;  2K0Y A;  1T8K A;  2M8L A;  3EJB A;  1IUQ A;  2EHS A;  3G21 A;  2KOR A;  2XV6 A;  3G0V A;  2NO8 A;  1VQ8 P;  2LKI A;  2PEJ A;  4PWV B;  2KW2 A;  3CCJ P;  1UJZ A;  1KD1 Q;  2GZJ A;  4XRO A;  2EG5 A;  4DG9 A;  4QNB A;  2JYG A;  1KLP A;  3CPW O;  3E2D A;  3OW2 O;  2FQ1 A;  2PEQ A;  2XZ0 D;  1DNY A;  3CCL P;  2M8P A;  3CCM P;  5HGL A;  2ONT A;  1QVF O;  1K8A Q;  3H0D A;  1MZ8 A;  2M5R A;  2FVE A;  5F2K A;  3CCQ P;  2E1M A;  4U0E A;  4PXH B;  1VQ7 P;  2MY5 A;  1F80 D;  1KC8 Q;  4GR6 A;  2JB0 A;  2PY8 A;  3NY7 B;  1CEI A;  1QRJ A;  2N6Z A;  2QNW A;  3CCE P;  2LIU A;  3B5I A;  3GJN A;  1W2B O;  1RNI A;  1AYI A;  1Q86 Q;  2N5I A;  3I56 P;  2FAC A;  2KG6 A;  4MRT C;  1IMP A;  2LML A;  3EJE A;  1A8O A;  4CA3 A;  3LRY A;  2LTE A;  1QVG O;  2OTL P;  4IPY A;  2FQ0 A;  3NTE A;  1GXG A;  3DS4 A;  2PNG A;  2KOS A;  5EJD A;  2CQ8 A;  4U0D A;  3DS2 A;  1YI2 P;  3B4Q A;  1VQO P;  2JYL A;  2AVA A;  2BHV A;  2GZG A;  2JAZ A;  4XFZ A;  1GPJ A;  5HGM A;  1BAJ A;  2ERH A;  2VLP A;  2KGC A;  4WYM A;  3HYB A;  3MGE A;  2FAE A;  4HKG A;  2KGA A;  2OAR A;  4COP A;  2KGD A;  3RG2 A;  2JO0 A;  1BXI A;  4COC A;  3DS3 A;  2EHT A;  1JJ2 O;  1L0I A;  1M6N A;  4H2W C;  1E0H A;  2N98 A;  1YJW P;  4XFX A;  5KP8 B;  2PEI A;  4NEO A;  4PH1 A;  2FHS C;  3CCS P;  5HVC A;  5DCK A;  1DV5 A;  3CMA P;  1IMQ A;  1Q81 Q;  1VQL P;  5HGN A;  2JQ4 A;  3H47 A;  2PEK A;  1Q82 Q;  2VSQ A;  2CWO A;  3HZQ A;  1M6E X;  1AUM A;  2OTJ P;  1YHQ P;  1NQ4 A;  2FVF A;  1K73 Q;  2GZE A;  1ZMB A;  2K94 A;  3CC7 P;  1HQB A;  2K93 A;  2KOD A;  2X2B A;  2KR5 A;  3CE7 A;  2KGE A;  3RG6 C;  1EOQ A;  5BS1 A;  3G28 A;  3M1M A;  3LMO A;  3DS0 A;  5KP6 B;  5HGO A;  1AF8 A;  3G1G A;  4BPH A;  3H4E A;  2JU2 A;  2XZ1 C;  4UHP B;  2QEX P;  1YIJ P;  2N6Y A;  2PEO A;  4PH0 A;  1FR2 A;  1M74 A;  2ROQ A;  3GZM A;  5KP7 B;  2KG8 A;  2QA4 P;  2LPK A;  2K2Q A;  1RO0 A;  2FVA A;  2XT1 A;  3DS1 A;  4IZ6 A;  3VRL C;  2CGQ A;  2N50 A;  1VQ5 P;  1VQ9 P;  3DS5 A;  2K92 A;  2Z46 A;  2L0Q A;  2MD9 A;  1UNK A;  1D1D A;  2GDY A;  1VKU A;  4U0A A;  2FQ2 A;  2KOQ A;  2WPT A;  3CD6 P;  4H2Y C;  3G6E P;  2JBG A;  2KG9 A;  3CME P;  2MR7 A;  1RO2 A;  5EW5 E;  2VLN A;  3G4S P;  1OR5 A;  7CEI A;  3U43 A;  2BUO A;  3CCV P;  2GDW A;  2Z45 A;  2CNR A;  2PEM A;  3WBH A;  3CCR P;  1K9M Q;  1VHN A;  1EIA A;  2L22 A;  3P05 A;  2JU1 A;  1A43 A; 
#chains in the Genus database with same CATH homology
 1FR2 A;  1BXI A;  1IMQ A;  2GYK A;  2GZJ A;  2JAZ A;  2GZG A;  3GJN A;  1UNK A;  1MZ8 A;  1AYI A;  2VLQ A;  1GXH A;  2VLO A;  1GXG A;  1E0H A;  2ERH A;  4F37 A;  2VLP A;  2WPT A;  2GZF A;  2K5X A;  2JBG A;  1IMP A;  2NO8 A;  3GKL C;  4UHP B;  5EW5 E;  1EMV A;  2JB0 A;  2VLN A;  2GZI A;  1CEI A;  2GZE A;  2K0D X;  4QKO A;  7CEI A;  1ZNV A;  3U43 A;  1UJZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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