1ZNVA

How a his-metal finger endonuclease cole7 binds and cleaves dna with a transition metal ion cofactor
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
87
structure length
87
Chain Sequence
MELKNSISDYTEAEFVQLLKEIEKENVAATDDVLDVLLEHFVKITEHPDGTDLIYYPSDNRDDSPEGIVKEIKEWRAANGKPGFKQG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structural analysis and metal-dependent stability and activity studies of the ColE7 endonuclease domain in complex with DNA/Zn2+ or inhibitor/Ni2+
pubmed doi rcsb
molecule tags Hydrolase/protein binding
source organism Escherichia coli str. k12 substr.
molecule keywords Colicin E7 immunity protein
total genus 29
structure length 87
sequence length 87
chains with identical sequence C
ec nomenclature
pdb deposition date 2005-05-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01320 Colicin_Pyocin Colicin immunity protein / pyocin immunity protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.20 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Colicin E immunity protein 1znvA00
3GKLC 2VLNA 5EW5E 1BXIA 1UJZA 2GZJA 2NO8A 2GYKA 4F37A 2GZEA 2JAZA 2JBGA 2VLPA 2WPTA 1FR2A 1GXGA 2GZIA 1CEIA 2VLQA 2K0DX 1IMPA 1AYIA 1E0HA 2ERHA 1ZNVA 3U43A 2VLOA 1MZ8A 2GZFA 4UHPB 7CEIA 2K5XA 3GJNA 4QKOA 1GXHA 1UNKA 2JB0A 1EMVA 2GZGA 1IMQA
chains in the Genus database with same CATH superfamily
1BXIA 2BHVA 1CEIA 3CCJP 2MVVA 3U43A 1F80D 1MZ8A 3CMEP 2K5XA 4H2YC 3CMAP 3GKLC 2MY5A 4R0MA 2CNRA 2M8PA 2JYLA 3CCUP 1L0IA 2JAZA 5HVCA 1HY8A 4U0EA 2KGEA 2QA4P 3G28A 2MD9A 2GDWA 1VQ8P 1YHQP 2PEOA 3NTEA 2PNGA 1VQ4P 2PEKA 1QVFO 2EHSA 2XV6A 2MVUA 2AFEA 2N98A 4QNBA 1Q86Q 5KP7B 5BS2A 2EFJA 3DS3A 2FQ0A 2JGPA 3B5IA 1KLPA 2JO0A 5CZDB 2BUOA 1Z6MA 2KW2A 1HQBA 2N5HA 2JB0A 2VLQA 3B4QA 1YJWP 3CCEP 2P9XA 3G26A 4DG9A 4H2WC 3E2DA 3H4EA 3CD6P 3M1MA 4QKOA 1UNKA 4BPFA 1M6NA 3WBHA 2KGCA 1K9MQ 3HZQA 4HKGA 3DS4A 2ONTA 2GZEA 2KG6A 5HV8A 5BS1A 3LMOA 2AFDA 2JU1A 4PH1A 3GZMA 2ERHA 2VLOA 4BPGA 2QNWA 2GZFA 5HGNA 3LRYA 1M90Q 3NY7B 3RG2A 5JPAA 1VQ7P 2DNWA 3G29A 2LMLA 2GZIA 3CPWO 2FAEA 2PENA 2ROQA 2K0DX 1VQ5P 2FVAA 1E0HA 3G71P 1DV5A 2KG8A 1VKUA 1GPJA 2EIAA 2M5RA 2PEJA 5EW5E 1VQKP 2DGYA 1YJNP 4XFZA 1S72P 2K0YA 1RO2A 2FADA 1VHNA 1IUQA 1QVGO 5EJDA 5HGLA 1M6EX 1KQSO 2OTJP 1KD1Q 1VQ9P 3GZLA 2GDYA 2OARA 3VRLC 2FHSC 2MR8A 2GYKA 4U0CA 1NJIQ 2WPTA 2N50A 2JQ4A 2FVFA 2LTEA 3H0DA 4PH0A 1E6JP 3CCLP 2K2QA 2KOPA 3RG6C 2GZGA 2CQ8A 2XZ1C 4NEOA 3P05A 1D1DA 2M8NA 2KOQA 2FQ1A 2L6EA 4XFYA 1N8RQ 2JBGA 2VLPA 1W2BO 2CWOA 1GXGA 1K8AQ 1DNYA 2XT1A 2LKIA 1X3OA 1KC8Q 4GR6A 1GXHA 1OR5A 1YITP 2LOLA 2VSQA 2KODA 2L9FA 5HGMA 4CA3A 1QRJA 1Q82Q 2K94A 1VQNP 2L22A 3G0VA 3EJDA 4PWVB 1AYIA 2PY8A 2EHTA 1NQ4A 2LL8A 3EJBA 1EMVA 4U0DA 1L0HA 2AVAA 3H47A 1RO0A 1EOQA 2LPKA 1YIJP 1VQLP 1JJ2O 2Z45A 1IMPA 1YI2P 4BPHA 1T8KA 1ZNVA 1K30A 2E1MA 1VQOP 1AUMA 2GDXA 7CEIA 3GJNA 2PEMA 4IPYA 2FACA 2LIUA 2Z44A 2L0QA 2KWLA 3DS2A 1VQMP 2NO8A 2QEXP 3DTJA 2N5IA 1YJ9P 2OTLP 5HGOA 2L4BA 4COPA 2X2BA 2KORA 1ACPA 3G6EP 2N6YA 4PXHB 3CCQP 4U0FA 3CCSP 3DPHA 3CCMP 1A43A 1VQ6P 1K73Q 1ZMBA 2Z46A 2KR5A 5KP8B 2KG9A 3CCVP 2XZ0D 4XROA 4UHPB 4WYMA 4M0IA 3EJEA 2KOSA 2LF4A 2VLNA 4GR2A 1UJZA 2GZJA 2AF8A 4IZ6A 1VQPP 2KOOA 2CG5B 3Q20A 2K92A 4MRTC 3CCRP 2EG5A 2JU2A 3I56P 2PEQA 4U0AA 1M74A 1M1KQ 3DS1A 2N6ZA 2FVEA 1Q81Q 2K93A 2LIWA 2K0XA 3CXCO 3DS0A 1FR2A 4H2XC 2MF4A 1AF8A 2CGQA 2JYGA 3G1GA 3DS5A 5I4TG 2XXMA 4U0BA 1A8OA 3HYBA 3OW2O 2M8LA 3CC2P 4XRQA 5KP6B 1IMQA 1RNIA 3G21A 3CC7P 3MGEA 5F2OA 4F37A 2KGAA 3I55P 3CE7A 4COCA 1EIAA 5F2KA 3CC4P 2FQ2A 1BAJA 2PEIA 2MR7A 5DCKA 1Q7YQ 4XFXA 2KGDA 3G1IA 5F2NA 3G4SP
chains in the Genus database with same CATH topology
3GKLC 2VLNA 5EW5E 1BXIA 1UJZA 2GZJA 2NO8A 2GYKA 4F37A 2GZEA 2JAZA 2JBGA 2VLPA 2WPTA 1FR2A 1GXGA 2GZIA 1CEIA 2VLQA 2K0DX 1IMPA 1AYIA 1E0HA 2ERHA 1ZNVA 3U43A 2VLOA 1MZ8A 2GZFA 4UHPB 7CEIA 2K5XA 3GJNA 4QKOA 1GXHA 1UNKA 2JB0A 1EMVA 2GZGA 1IMQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GKL C;  2VLN A;  5EW5 E;  1BXI A;  1UJZ A;  2GZJ A;  2NO8 A;  2GYK A;  4F37 A;  2GZE A;  2JAZ A;  2JBG A;  2VLP A;  2WPT A;  1FR2 A;  1GXG A;  2GZI A;  1CEI A;  2VLQ A;  2K0D X;  1IMP A;  1AYI A;  1E0H A;  2ERH A;  1ZNV A;  3U43 A;  2VLO A;  1MZ8 A;  2GZF A;  4UHP B;  7CEI A;  2K5X A;  3GJN A;  4QKO A;  1GXH A;  1UNK A;  2JB0 A;  1EMV A;  2GZG A;  1IMQ A; 
#chains in the Genus database with same CATH topology
 1BXI A;  2BHV A;  1CEI A;  3CCJ P;  2MVV A;  3U43 A;  1F80 D;  1MZ8 A;  3CME P;  2K5X A;  4H2Y C;  3CMA P;  3GKL C;  2MY5 A;  4R0M A;  2CNR A;  2M8P A;  2JYL A;  3CCU P;  1L0I A;  2JAZ A;  5HVC A;  1HY8 A;  4U0E A;  2KGE A;  2QA4 P;  3G28 A;  2MD9 A;  2GDW A;  1VQ8 P;  1YHQ P;  2PEO A;  3NTE A;  2PNG A;  1VQ4 P;  2PEK A;  1QVF O;  2EHS A;  2XV6 A;  2MVU A;  2AFE A;  2N98 A;  4QNB A;  1Q86 Q;  5KP7 B;  5BS2 A;  2EFJ A;  3DS3 A;  2FQ0 A;  2JGP A;  3B5I A;  1KLP A;  2JO0 A;  5CZD B;  2BUO A;  1Z6M A;  2KW2 A;  1HQB A;  2N5H A;  2JB0 A;  2VLQ A;  3B4Q A;  1YJW P;  3CCE P;  2P9X A;  3G26 A;  4DG9 A;  4H2W C;  3E2D A;  3H4E A;  3CD6 P;  3M1M A;  4QKO A;  1UNK A;  4BPF A;  1M6N A;  3WBH A;  2KGC A;  1K9M Q;  3HZQ A;  4HKG A;  3DS4 A;  2ONT A;  2GZE A;  2KG6 A;  5HV8 A;  5BS1 A;  3LMO A;  2AFD A;  2JU1 A;  4PH1 A;  3GZM A;  2ERH A;  2VLO A;  4BPG A;  2QNW A;  2GZF A;  5HGN A;  3LRY A;  1M90 Q;  3NY7 B;  3RG2 A;  5JPA A;  1VQ7 P;  2DNW A;  3G29 A;  2LML A;  2GZI A;  3CPW O;  2FAE A;  2PEN A;  2ROQ A;  2K0D X;  1VQ5 P;  2FVA A;  1E0H A;  3G71 P;  1DV5 A;  2KG8 A;  1VKU A;  1GPJ A;  2EIA A;  2M5R A;  2PEJ A;  5EW5 E;  1VQK P;  2DGY A;  1YJN P;  4XFZ A;  1S72 P;  2K0Y A;  1RO2 A;  2FAD A;  1VHN A;  1IUQ A;  1QVG O;  5EJD A;  5HGL A;  1M6E X;  1KQS O;  2OTJ P;  1KD1 Q;  1VQ9 P;  3GZL A;  2GDY A;  2OAR A;  3VRL C;  2FHS C;  2MR8 A;  2GYK A;  4U0C A;  1NJI Q;  2WPT A;  2N50 A;  2JQ4 A;  2FVF A;  2LTE A;  3H0D A;  4PH0 A;  1E6J P;  3CCL P;  2K2Q A;  2KOP A;  3RG6 C;  2GZG A;  2CQ8 A;  2XZ1 C;  4NEO A;  3P05 A;  1D1D A;  2M8N A;  2KOQ A;  2FQ1 A;  2L6E A;  4XFY A;  1N8R Q;  2JBG A;  2VLP A;  1W2B O;  2CWO A;  1GXG A;  1K8A Q;  1DNY A;  2XT1 A;  2LKI A;  1X3O A;  1KC8 Q;  4GR6 A;  1GXH A;  1OR5 A;  1YIT P;  2LOL A;  2VSQ A;  2KOD A;  2L9F A;  5HGM A;  4CA3 A;  1QRJ A;  1Q82 Q;  2K94 A;  1VQN P;  2L22 A;  3G0V A;  3EJD A;  4PWV B;  1AYI A;  2PY8 A;  2EHT A;  1NQ4 A;  2LL8 A;  3EJB A;  1EMV A;  4U0D A;  1L0H A;  2AVA A;  3H47 A;  1RO0 A;  1EOQ A;  2LPK A;  1YIJ P;  1VQL P;  1JJ2 O;  2Z45 A;  1IMP A;  1YI2 P;  4BPH A;  1T8K A;  1ZNV A;  1K30 A;  2E1M A;  1VQO P;  1AUM A;  2GDX A;  7CEI A;  3GJN A;  2PEM A;  4IPY A;  2FAC A;  2LIU A;  2Z44 A;  2L0Q A;  2KWL A;  3DS2 A;  1VQM P;  2NO8 A;  2QEX P;  3DTJ A;  2N5I A;  1YJ9 P;  2OTL P;  5HGO A;  2L4B A;  4COP A;  2X2B A;  2KOR A;  1ACP A;  3G6E P;  2N6Y A;  4PXH B;  3CCQ P;  4U0F A;  3CCS P;  3DPH A;  3CCM P;  1A43 A;  1VQ6 P;  1K73 Q;  1ZMB A;  2Z46 A;  2KR5 A;  5KP8 B;  2KG9 A;  3CCV P;  2XZ0 D;  4XRO A;  4UHP B;  4WYM A;  4M0I A;  3EJE A;  2KOS A;  2LF4 A;  2VLN A;  4GR2 A;  1UJZ A;  2GZJ A;  2AF8 A;  4IZ6 A;  1VQP P;  2KOO A;  2CG5 B;  3Q20 A;  2K92 A;  4MRT C;  3CCR P;  2EG5 A;  2JU2 A;  3I56 P;  2PEQ A;  4U0A A;  1M74 A;  1M1K Q;  3DS1 A;  2N6Z A;  2FVE A;  1Q81 Q;  2K93 A;  2LIW A;  2K0X A;  3CXC O;  3DS0 A;  1FR2 A;  4H2X C;  2MF4 A;  1AF8 A;  2CGQ A;  2JYG A;  3G1G A;  3DS5 A;  5I4T G;  2XXM A;  4U0B A;  1A8O A;  3HYB A;  3OW2 O;  2M8L A;  3CC2 P;  4XRQ A;  5KP6 B;  1IMQ A;  1RNI A;  3G21 A;  3CC7 P;  3MGE A;  5F2O A;  4F37 A;  2KGA A;  3I55 P;  3CE7 A;  4COC A;  1EIA A;  5F2K A;  3CC4 P;  2FQ2 A;  1BAJ A;  2PEI A;  2MR7 A;  5DCK A;  1Q7Y Q;  4XFX A;  2KGD A;  3G1I A;  5F2N A;  3G4S P; 
#chains in the Genus database with same CATH homology
 3GKL C;  2VLN A;  5EW5 E;  1BXI A;  1UJZ A;  2GZJ A;  2NO8 A;  2GYK A;  4F37 A;  2GZE A;  2JAZ A;  2JBG A;  2VLP A;  2WPT A;  1FR2 A;  1GXG A;  2GZI A;  1CEI A;  2VLQ A;  2K0D X;  1IMP A;  1AYI A;  1E0H A;  2ERH A;  1ZNV A;  3U43 A;  2VLO A;  1MZ8 A;  2GZF A;  4UHP B;  7CEI A;  2K5X A;  3GJN A;  4QKO A;  1GXH A;  1UNK A;  2JB0 A;  1EMV A;  2GZG A;  1IMQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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