2CG5B

Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme a
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
71
structure length
71
Chain Sequence
QRDLVEAVAHILGIRDLAAVNLDSSLADLGLDALMSVEVRQTLERELNLVLSVREVRQLTLRKLQELSSKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mechanism and Substrate Recognition of Human Holo Acp Synthase.
pubmed doi rcsb
molecule tags Transferase/hydrolase
source organism Homo sapiens
molecule keywords L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINY
total genus 19
structure length 71
sequence length 71
ec nomenclature ec 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase.
pdb deposition date 2006-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 2cg5B00
2KGCA 4NEOA 1AF8A 3NY7B 2K93A 2L0QA 2CNRA 2M5RA 1HQBA 2GDYA 4HKGA 2CQ8A 2FVEA 3EJEA 4H2YC 2LL8A 2MVVA 1T8KA 4MRTC 2XZ0D 2KWLA 2AF8A 3LMOA 2N6YA 2LPKA 5CZDB 1F80D 2K0XA 2FQ1A 2MR7A 2KOSA 2LOLA 2L4BA 2FACA 2GDWA 2KGDA 2DNWA 2MY5A 4CA3A 2FADA 5HV8A 2FVFA 2N50A 2K92A 2VSQA 2N6ZA 2LTEA 2FQ0A 2KW2A 2KG8A 5KP7B 2AVAA 2KOQA 2PNGA 2GDXA 2K94A 1HY8A 1L0HA 4BPHA 2AFEA 2MR8A 3EJDA 2AFDA 2KOOA 5KP6B 1DNYA 2N5IA 2L9FA 2KG6A 4BPFA 4PXHB 2EHTA 1L0IA 3CE7A 2FHSC 2N5HA 1VKUA 2LIUA 2LMLA 2MVUA 4R0MA 2KG9A 3GZMA 2XZ1C 2CG5B 3EJBA 2MF4A 2JGPA 4DG9A 1KLPA 4PWVB 2CGQA 2X2BA 3RG2A 2QNWA 2FQ2A 2LKIA 2EHSA 1OR5A 2JQ4A 2ROQA 3GZLA 2KORA 5HVCA 2KGEA 2JU2A 4IZ6A 2KR5A 1X3OA 1DV5A 4H2WC 2FVAA 2K0YA 5KP8B 2MD9A 2N98A 4H2XC 2JU1A 1ACPA 2KOPA 2FAEA 5EJDA 2KGAA 4BPGA 2L22A 1NQ4A 2K2QA 2LIWA
chains in the Genus database with same CATH superfamily
2K93A 2ERHA 2CQ8A 2FVEA 1QVFO 1UJZA 1T8KA 3MGEA 2XZ0D 2NO8A 2KWLA 1NJIQ 1GXHA 2K0DX 2OTJP 1VQ5P 2JB0A 2GDWA 1VQNP 4U0DA 4UHPB 2FADA 5HV8A 2PEOA 1E0HA 2FQ0A 1UNKA 2KG8A 1YHQP 2KOQA 5F2NA 5JPAA 1QRJA 3GJNA 3G28A 2AFEA 3CCRP 2E1MA 1Q86Q 4WYMA 1QVGO 3U43A 2KG6A 3H4EA 1L0IA 2PEMA 3CE7A 2KODA 2LIUA 3H47A 4M0IA 1VQ7P 5I4TG 1YITP 3G1GA 1KQSO 2MF4A 1KLPA 1VHNA 4QKOA 3G29A 2X2BA 3RG2A 2QNWA 2LKIA 4XRQA 2ROQA 3GZLA 2KORA 3CCVP 4U0FA 4F37A 3NTEA 5F2OA 3I55P 5KP8B 2JU1A 3G21A 2KOPA 2JYGA 3CCLP 2LIWA 2DNWA 1KC8Q 2GZEA 3M1MA 4XROA 3CPWO 4HKGA 1CEIA 2GZJA 3DS5A 3Q20A 4MRTC 1Q7YQ 2M8NA 5HGLA 3RG6C 2XXMA 5CZDB 4COPA 4XFYA 2KGDA 3G71P 2BUOA 3H0DA 1IMQA 1RO2A 2LTEA 2Z44A 1ZMBA 2DGYA 1D1DA 1FR2A 3CMAP 3CD6P 2K94A 4XFXA 3OW2O 4XFZA 1A43A 3B5IA 4U0BA 1MZ8A 3DPHA 5KP6B 4U0CA 1DNYA 2VLQA 2GYKA 3CCJP 4BPFA 2L6EA 2M8LA 3CCMP 2FHSC 2N5HA 1K9MQ 2MVUA 4R0MA 1VQ4P 3DS2A 4PH0A 2VLPA 2JO0A 3CXCO 4PWVB 3CC7P 3G6EP 2JQ4A 3DTJA 1EIAA 1K8AQ 4IZ6A 2PENA 1BXIA 5HGMA 2XV6A 2JBGA 2MD9A 1ACPA 1M6NA 2FAEA 5EJDA 1VQPP 2KGAA 1RO0A 2WPTA 4NEOA 3LRYA 5DCKA 4COCA 1Q81Q 1HQBA 2PEIA 2PEKA 3EJEA 4H2YC 3DS1A 2MVVA 2EFJA 2OARA 2K5XA 3I56P 2AF8A 1YJNP 5EW5E 3G26A 1F80D 1S72P 2MR7A 2KOSA 2QEXP 2LOLA 2FACA 1M6EX 2MY5A 2K92A 2VLNA 2VSQA 2XT1A 2KW2A 2AVAA 4PH1A 1GXGA 1AUMA 2PNGA 1VQLP 1RNIA 2PY8A 2KOOA 3G4SP 3CCUP 1EOQA 2N5IA 1KD1Q 3CCEP 2L9FA 1VQ9P 1EMVA 1ZNVA 2GZFA 2PEJA 1A8OA 2CG5B 3EJBA 1Z6MA 3CCSP 2EHSA 1OR5A 2M8PA 2P9XA 2CWOA 3CC4P 2KR5A 1X3OA 3CMEP 3B4QA 1W2BO 1DV5A 2FVAA 3DS0A 2K0YA 2VLOA 1Q82Q 1N8RQ 1IUQA 1JJ2O 3P05A 2OTLP 2Z45A 2L22A 1VQOP 5BS1A 2K2QA 2KGCA 1YJ9P 1AF8A 3NY7B 2L0QA 2CNRA 2M5RA 2ONTA 2GDYA 3G1IA 1BAJA 2LL8A 4GR2A 3HZQA 1IMPA 3WBHA 2JYLA 2LF4A 3GKLC 3LMOA 2N6YA 2LPKA 5HGOA 2K0XA 2FQ1A 2QA4P 1GPJA 2L4BA 3E2DA 1VQ8P 4CA3A 3VRLC 2FVFA 2N50A 1M74A 5BS2A 5F2KA 2N6ZA 4IPYA 5KP7B 2GZGA 3HYBA 2BHVA 2Z46A 2GDXA 1YIJP 1HY8A 4GR6A 4QNBA 1L0HA 1YJWP 4BPHA 2MR8A 3EJDA 2AFDA 2EIAA 5HGNA 3CC2P 3DS4A 4PXHB 2EHTA 1YI2P 3DS3A 1M90Q 1K73Q 1VKUA 1VQKP 1VQ6P 1AYIA 2LMLA 2KG9A 3GZMA 1K30A 2XZ1C 2JGPA 4DG9A 2EG5A 2CGQA 2GZIA 3CCQP 2FQ2A 1VQMP 3G0VA 1M1KQ 5HVCA 7CEIA 2KGEA 1E6JP 2JU2A 4U0AA 2PEQA 4H2WC 2N98A 4H2XC 4U0EA 2JAZA 4BPGA 1NQ4A
chains in the Genus database with same CATH topology
2KGCA 4NEOA 1AF8A 3NY7B 2K93A 2L0QA 2CNRA 2M5RA 1HQBA 2GDYA 4HKGA 2CQ8A 2FVEA 3EJEA 4H2YC 2LL8A 2MVVA 1T8KA 4MRTC 2XZ0D 2KWLA 2AF8A 3LMOA 2N6YA 2LPKA 5CZDB 1F80D 2K0XA 2FQ1A 2MR7A 2KOSA 2LOLA 2L4BA 2FACA 2GDWA 2KGDA 2DNWA 2MY5A 4CA3A 2FADA 5HV8A 2FVFA 2N50A 2K92A 2VSQA 2N6ZA 2LTEA 2FQ0A 2KW2A 2KG8A 5KP7B 2AVAA 2KOQA 2PNGA 2GDXA 2K94A 1HY8A 1L0HA 4BPHA 2AFEA 2MR8A 3EJDA 2AFDA 2KOOA 5KP6B 1DNYA 2N5IA 2L9FA 2KG6A 4BPFA 4PXHB 2EHTA 1L0IA 3CE7A 2FHSC 2N5HA 1VKUA 2LIUA 2LMLA 2MVUA 4R0MA 2KG9A 3GZMA 2XZ1C 2CG5B 3EJBA 2MF4A 2JGPA 4DG9A 1KLPA 4PWVB 2CGQA 2X2BA 3RG2A 2QNWA 2FQ2A 2LKIA 2EHSA 1OR5A 2JQ4A 2ROQA 3GZLA 2KORA 5HVCA 2KGEA 2JU2A 4IZ6A 2KR5A 1X3OA 1DV5A 4H2WC 2FVAA 2K0YA 5KP8B 2MD9A 2N98A 4H2XC 2JU1A 1ACPA 2KOPA 2FAEA 5EJDA 2KGAA 4BPGA 2L22A 1NQ4A 2K2QA 2LIWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KGC A;  4NEO A;  1AF8 A;  3NY7 B;  2K93 A;  2L0Q A;  2CNR A;  2M5R A;  1HQB A;  2GDY A;  4HKG A;  2CQ8 A;  2FVE A;  3EJE A;  4H2Y C;  2LL8 A;  2MVV A;  1T8K A;  4MRT C;  2XZ0 D;  2KWL A;  2AF8 A;  3LMO A;  2N6Y A;  2LPK A;  5CZD B;  1F80 D;  2K0X A;  2FQ1 A;  2MR7 A;  2KOS A;  2LOL A;  2L4B A;  2FAC A;  2GDW A;  2KGD A;  2DNW A;  2MY5 A;  4CA3 A;  2FAD A;  5HV8 A;  2FVF A;  2N50 A;  2K92 A;  2VSQ A;  2N6Z A;  2LTE A;  2FQ0 A;  2KW2 A;  2KG8 A;  5KP7 B;  2AVA A;  2KOQ A;  2PNG A;  2GDX A;  2K94 A;  1HY8 A;  1L0H A;  4BPH A;  2AFE A;  2MR8 A;  3EJD A;  2AFD A;  2KOO A;  5KP6 B;  1DNY A;  2N5I A;  2L9F A;  2KG6 A;  4BPF A;  4PXH B;  2EHT A;  1L0I A;  3CE7 A;  2FHS C;  2N5H A;  1VKU A;  2LIU A;  2LML A;  2MVU A;  4R0M A;  2KG9 A;  3GZM A;  2XZ1 C;  2CG5 B;  3EJB A;  2MF4 A;  2JGP A;  4DG9 A;  1KLP A;  4PWV B;  2CGQ A;  2X2B A;  3RG2 A;  2QNW A;  2FQ2 A;  2LKI A;  2EHS A;  1OR5 A;  2JQ4 A;  2ROQ A;  3GZL A;  2KOR A;  5HVC A;  2KGE A;  2JU2 A;  4IZ6 A;  2KR5 A;  1X3O A;  1DV5 A;  4H2W C;  2FVA A;  2K0Y A;  5KP8 B;  2MD9 A;  2N98 A;  4H2X C;  2JU1 A;  1ACP A;  2KOP A;  2FAE A;  5EJD A;  2KGA A;  4BPG A;  2L22 A;  1NQ4 A;  2K2Q A;  2LIW A; 
#chains in the Genus database with same CATH topology
 2K93 A;  2ERH A;  2CQ8 A;  2FVE A;  1QVF O;  1UJZ A;  1T8K A;  3MGE A;  2XZ0 D;  2NO8 A;  2KWL A;  1NJI Q;  1GXH A;  2K0D X;  2OTJ P;  1VQ5 P;  2JB0 A;  2GDW A;  1VQN P;  4U0D A;  4UHP B;  2FAD A;  5HV8 A;  2PEO A;  1E0H A;  2FQ0 A;  1UNK A;  2KG8 A;  1YHQ P;  2KOQ A;  5F2N A;  5JPA A;  1QRJ A;  3GJN A;  3G28 A;  2AFE A;  3CCR P;  2E1M A;  1Q86 Q;  4WYM A;  1QVG O;  3U43 A;  2KG6 A;  3H4E A;  1L0I A;  2PEM A;  3CE7 A;  2KOD A;  2LIU A;  3H47 A;  4M0I A;  1VQ7 P;  5I4T G;  1YIT P;  3G1G A;  1KQS O;  2MF4 A;  1KLP A;  1VHN A;  4QKO A;  3G29 A;  2X2B A;  3RG2 A;  2QNW A;  2LKI A;  4XRQ A;  2ROQ A;  3GZL A;  2KOR A;  3CCV P;  4U0F A;  4F37 A;  3NTE A;  5F2O A;  3I55 P;  5KP8 B;  2JU1 A;  3G21 A;  2KOP A;  2JYG A;  3CCL P;  2LIW A;  2DNW A;  1KC8 Q;  2GZE A;  3M1M A;  4XRO A;  3CPW O;  4HKG A;  1CEI A;  2GZJ A;  3DS5 A;  3Q20 A;  4MRT C;  1Q7Y Q;  2M8N A;  5HGL A;  3RG6 C;  2XXM A;  5CZD B;  4COP A;  4XFY A;  2KGD A;  3G71 P;  2BUO A;  3H0D A;  1IMQ A;  1RO2 A;  2LTE A;  2Z44 A;  1ZMB A;  2DGY A;  1D1D A;  1FR2 A;  3CMA P;  3CD6 P;  2K94 A;  4XFX A;  3OW2 O;  4XFZ A;  1A43 A;  3B5I A;  4U0B A;  1MZ8 A;  3DPH A;  5KP6 B;  4U0C A;  1DNY A;  2VLQ A;  2GYK A;  3CCJ P;  4BPF A;  2L6E A;  2M8L A;  3CCM P;  2FHS C;  2N5H A;  1K9M Q;  2MVU A;  4R0M A;  1VQ4 P;  3DS2 A;  4PH0 A;  2VLP A;  2JO0 A;  3CXC O;  4PWV B;  3CC7 P;  3G6E P;  2JQ4 A;  3DTJ A;  1EIA A;  1K8A Q;  4IZ6 A;  2PEN A;  1BXI A;  5HGM A;  2XV6 A;  2JBG A;  2MD9 A;  1ACP A;  1M6N A;  2FAE A;  5EJD A;  1VQP P;  2KGA A;  1RO0 A;  2WPT A;  4NEO A;  3LRY A;  5DCK A;  4COC A;  1Q81 Q;  1HQB A;  2PEI A;  2PEK A;  3EJE A;  4H2Y C;  3DS1 A;  2MVV A;  2EFJ A;  2OAR A;  2K5X A;  3I56 P;  2AF8 A;  1YJN P;  5EW5 E;  3G26 A;  1F80 D;  1S72 P;  2MR7 A;  2KOS A;  2QEX P;  2LOL A;  2FAC A;  1M6E X;  2MY5 A;  2K92 A;  2VLN A;  2VSQ A;  2XT1 A;  2KW2 A;  2AVA A;  4PH1 A;  1GXG A;  1AUM A;  2PNG A;  1VQL P;  1RNI A;  2PY8 A;  2KOO A;  3G4S P;  3CCU P;  1EOQ A;  2N5I A;  1KD1 Q;  3CCE P;  2L9F A;  1VQ9 P;  1EMV A;  1ZNV A;  2GZF A;  2PEJ A;  1A8O A;  2CG5 B;  3EJB A;  1Z6M A;  3CCS P;  2EHS A;  1OR5 A;  2M8P A;  2P9X A;  2CWO A;  3CC4 P;  2KR5 A;  1X3O A;  3CME P;  3B4Q A;  1W2B O;  1DV5 A;  2FVA A;  3DS0 A;  2K0Y A;  2VLO A;  1Q82 Q;  1N8R Q;  1IUQ A;  1JJ2 O;  3P05 A;  2OTL P;  2Z45 A;  2L22 A;  1VQO P;  5BS1 A;  2K2Q A;  2KGC A;  1YJ9 P;  1AF8 A;  3NY7 B;  2L0Q A;  2CNR A;  2M5R A;  2ONT A;  2GDY A;  3G1I A;  1BAJ A;  2LL8 A;  4GR2 A;  3HZQ A;  1IMP A;  3WBH A;  2JYL A;  2LF4 A;  3GKL C;  3LMO A;  2N6Y A;  2LPK A;  5HGO A;  2K0X A;  2FQ1 A;  2QA4 P;  1GPJ A;  2L4B A;  3E2D A;  1VQ8 P;  4CA3 A;  3VRL C;  2FVF A;  2N50 A;  1M74 A;  5BS2 A;  5F2K A;  2N6Z A;  4IPY A;  5KP7 B;  2GZG A;  3HYB A;  2BHV A;  2Z46 A;  2GDX A;  1YIJ P;  1HY8 A;  4GR6 A;  4QNB A;  1L0H A;  1YJW P;  4BPH A;  2MR8 A;  3EJD A;  2AFD A;  2EIA A;  5HGN A;  3CC2 P;  3DS4 A;  4PXH B;  2EHT A;  1YI2 P;  3DS3 A;  1M90 Q;  1K73 Q;  1VKU A;  1VQK P;  1VQ6 P;  1AYI A;  2LML A;  2KG9 A;  3GZM A;  1K30 A;  2XZ1 C;  2JGP A;  4DG9 A;  2EG5 A;  2CGQ A;  2GZI A;  3CCQ P;  2FQ2 A;  1VQM P;  3G0V A;  1M1K Q;  5HVC A;  7CEI A;  2KGE A;  1E6J P;  2JU2 A;  4U0A A;  2PEQ A;  4H2W C;  2N98 A;  4H2X C;  4U0E A;  2JAZ A;  4BPG A;  1NQ4 A; 
#chains in the Genus database with same CATH homology
 2KGC A;  4NEO A;  1AF8 A;  3NY7 B;  2K93 A;  2L0Q A;  2CNR A;  2M5R A;  1HQB A;  2GDY A;  4HKG A;  2CQ8 A;  2FVE A;  3EJE A;  4H2Y C;  2LL8 A;  2MVV A;  1T8K A;  4MRT C;  2XZ0 D;  2KWL A;  2AF8 A;  3LMO A;  2N6Y A;  2LPK A;  5CZD B;  1F80 D;  2K0X A;  2FQ1 A;  2MR7 A;  2KOS A;  2LOL A;  2L4B A;  2FAC A;  2GDW A;  2KGD A;  2DNW A;  2MY5 A;  4CA3 A;  2FAD A;  5HV8 A;  2FVF A;  2N50 A;  2K92 A;  2VSQ A;  2N6Z A;  2LTE A;  2FQ0 A;  2KW2 A;  2KG8 A;  5KP7 B;  2AVA A;  2KOQ A;  2PNG A;  2GDX A;  2K94 A;  1HY8 A;  1L0H A;  4BPH A;  2AFE A;  2MR8 A;  3EJD A;  2AFD A;  2KOO A;  5KP6 B;  1DNY A;  2N5I A;  2L9F A;  2KG6 A;  4BPF A;  4PXH B;  2EHT A;  1L0I A;  3CE7 A;  2FHS C;  2N5H A;  1VKU A;  2LIU A;  2LML A;  2MVU A;  4R0M A;  2KG9 A;  3GZM A;  2XZ1 C;  2CG5 B;  3EJB A;  2MF4 A;  2JGP A;  4DG9 A;  1KLP A;  4PWV B;  2CGQ A;  2X2B A;  3RG2 A;  2QNW A;  2FQ2 A;  2LKI A;  2EHS A;  1OR5 A;  2JQ4 A;  2ROQ A;  3GZL A;  2KOR A;  5HVC A;  2KGE A;  2JU2 A;  4IZ6 A;  2KR5 A;  1X3O A;  1DV5 A;  4H2W C;  2FVA A;  2K0Y A;  5KP8 B;  2MD9 A;  2N98 A;  4H2X C;  2JU1 A;  1ACP A;  2KOP A;  2FAE A;  5EJD A;  2KGA A;  4BPG A;  2L22 A;  1NQ4 A;  2K2Q A;  2LIW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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