2L6EA

Nmr structure of the monomeric mutant c-terminal domain of hiv-1 capsid in complex with stapled peptide inhibitor
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
94
structure length
94
Chain Sequence
SGLVPRGSHMTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNAATETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution structure of a hydrocarbon stapled peptide inhibitor in complex with monomeric C-terminal domain of HIV-1 capsid.
pubmed doi rcsb
molecule tags Viral protein/inhibitor
source organism Human immunodeficiency virus 1
molecule keywords Capsid protein p24
total genus 28
structure length 94
sequence length 94
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2010-11-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.30 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A 2l6eA00
1E6JP 3DS0A 3G26A 4COCA 5JPAA 3DPHA 4XFYA 2BUOA 4QNBA 4U0FA 4XFZA 4U0AA 3DS2A 4IPYA 1A8OA 5HGOA 4WYMA 3DTJA 2ONTA 5HGNA 3H4EA 5DCKA 2EIAA 3DS5A 2XV6A 3H47A 5HGMA 2JYGA 2JYLA 2M8LA 3G29A 3DS1A 2JO0A 2XT1A 4XRQA 1BAJA 2L6EA 3G0VA 3NTEA 3G1GA 1EOQA 4U0CA 4COPA 3LRYA 4U0BA 3DS3A 4U0EA 4PH1A 2KODA 3G28A 3MGEA 4XROA 4M0IA 1EIAA 3VRLC 4PH0A 5I4TG 5HGLA 1QRJA 3DS4A 1D1DA 2M8PA 2M8NA 3G21A 3P05A 2LF4A 2XXMA 4U0DA 1A43A 4XFXA 3G1IA 1AUMA
chains in the Genus database with same CATH superfamily
2AVAA 2MF4A 3DS0A 4U0AA 2GZJA 1A8OA 3H4EA 2DNWA 2CGQA 1X3OA 3I56P 1VQ9P 1YJNP 1T8KA 3G71P 4CA3A 2XXMA 1YI2P 1A43A 1AUMA 3CCLP 2DGYA 5EJDA 2K2QA 5HV8A 2PEOA 2LIUA 4H2XC 3CCMP 1VQPP 2P9XA 1YITP 3NTEA 7CEIA 4BPFA 1VHNA 1KD1Q 1F80D 2JGPA 3CCQP 5EW5E 2PNGA 2EHTA 1UNKA 4F37A 2KORA 2ONTA 2FVFA 1Q86Q 3CCUP 2VLNA 4COPA 2JU1A 3CC7P 2LIWA 2LMLA 3CCSP 4PH0A 1OR5A 1D1DA 2K5XA 2L0QA 2FVEA 2BHVA 4H2WC 2GZGA 2LTEA 2E1MA 2K0YA 3GJNA 2OARA 1VQ5P 2FAEA 2KOPA 2JYGA 3I55P 2VLOA 3CC2P 1EOQA 4U0BA 4PH1A 1EIAA 5I4TG 5HGLA 1DV5A 3RG6C 2EG5A 1YJ9P 1UJZA 4DG9A 2MVVA 3M1MA 3CD6P 2KOOA 1M1KQ 5DCKA 1ZNVA 1VQOP 3EJEA 1BAJA 1M6NA 1AYIA 2L6EA 4U0EA 2VLQA 1QRJA 1VQMP 3DPHA 3CXCO 2QA4P 2KG8A 2N5IA 4IPYA 3CCEP 2FADA 1KQSO 2JO0A 2L4BA 3MGEA 2MVUA 2PY8A 2QEXP 2Z45A 1M74A 4QNBA 2FVAA 2ERHA 2K93A 2M5RA 2PEIA 2MY5A 5KP7B 3G0VA 3CCRP 2LOLA 3CPWO 1N8RQ 2KOSA 1NQ4A 4XFXA 2CQ8A 2JU2A 1IUQA 4R0MA 2CG5B 4WYMA 2L9FA 2ROQA 1Q82Q 5HGMA 2L22A 1VQ6P 3G29A 1YHQP 3G1GA 2OTJP 1S72P 2K0DX 1K8AQ 1ZMBA 3GKLC 2KG9A 2FQ1A 3CC4P 4XFZA 5F2NA 1MZ8A 1FR2A 1KC8Q 3CMEP 3DS1A 3CCVP 1W2BO 2PEMA 1CEIA 2M8PA 5KP8B 1VQNP 1Z6MA 2CNRA 3G6EP 5KP6B 2N98A 5HGNA 2AF8A 1HQBA 1EMVA 3H47A 1VQ8P 1VQKP 2MR7A 1L0IA 1K73Q 1GXGA 2Z44A 3RG2A 3G28A 1K9MQ 4M0IA 1GPJA 1L0HA 3HYBA 4NEOA 1RNIA 3EJBA 2FQ0A 2EHSA 1E6JP 5BS1A 2NO8A 2KG6A 1DNYA 2EFJA 4UHPB 3DTJA 2XZ0D 3NY7B 2PENA 2GZIA 4H2YC 1Q7YQ 4U0CA 2GZFA 1QVGO 1VQ4P 3LRYA 4MRTC 3G21A 2KGCA 1JJ2O 2K92A 5JPAA 2LL8A 2GDYA 3B4QA 3DS2A 1M90Q 2KGEA 1AF8A 3DS5A 1RO2A 5F2OA 4QKOA 2N50A 2K0XA 4XROA 3OW2O 2VSQA 2AFEA 3P05A 4U0DA 3G1IA 1YJWP 3CCJP 2FACA 1HY8A 5CZDB 4GR2A 3E2DA 2M8LA 2LPKA 3G4SP 3H0DA 2QNWA 2GZEA 5F2KA 1KLPA 2LF4A 1IMPA 2WPTA 1QVFO 5HVCA 2VLPA 3DS3A 1NJIQ 3Q20A 3G26A 4COCA 1VKUA 2X2BA 1K30A 2KGDA 2N6ZA 4XFYA 3GZMA 3CMAP 2KR5A 2EIAA 3U43A 2JYLA 4BPGA 1RO0A 3VRLC 4XRQA 2PEKA 2OTLP 2FQ2A 2PEJA 2XZ1C 1Q81Q 2JBGA 2GDXA 2MD9A 2N6YA 2N5HA 1YIJP 3LMOA 2BUOA 4U0FA 1VQ7P 1ACPA 5HGOA 1VQLP 2XV6A 2Z46A 2KOQA 3GZLA 4GR6A 4BPHA 3B5IA 2MR8A 5BS2A 2KODA 4IZ6A 3EJDA 2FHSC 4HKGA 4PWVB 1E0HA 2JQ4A 3CE7A 3WBHA 2GDWA 2KWLA 1IMQA 2KW2A 4PXHB 1M6EX 3HZQA 2JB0A 2XT1A 2GYKA 2PEQA 1GXHA 2CWOA 2AFDA 1BXIA 2JAZA 2K94A 3DS4A 2M8NA 2LKIA 2KGAA
chains in the Genus database with same CATH topology
3RG6C 1YJWP 3DS0A 2EG5A 1YJ9P 3CCJP 3M1MA 3CD6P 3CC4P 4XFZA 4U0AA 5F2NA 1M1KQ 1A8OA 3H4EA 5DCKA 1KC8Q 4GR2A 3CMEP 1VQOP 3E2DA 2M8LA 3DS1A 3G4SP 1BAJA 1M6NA 2L6EA 4U0EA 3H0DA 3I56P 3CCVP 1W2BO 5F2KA 2PEMA 1YJNP 1QRJA 3G71P 1VQ9P 2M8PA 1VQNP 2LF4A 2XXMA 1YI2P 1QVFO 3DS3A 1A43A 1NJIQ 1AUMA 3Q20A 3G26A 4COCA 1VQMP 2DGYA 3CCLP 3DPHA 1K30A 3G6EP 3CXCO 4XFYA 2QA4P 3CMAP 4IPYA 3CCEP 5HGNA 2PEOA 2EIAA 1KQSO 1VQKP 3CCMP 3H47A 1VQPP 1VQ8P 2JYLA 2P9XA 1YITP 1RO0A 3VRLC 2JO0A 1K73Q 4XRQA 2Z44A 3NTEA 2PEKA 2OTLP 2PEJA 1Q81Q 3G28A 3MGEA 1K9MQ 4M0IA 1KD1Q 3HYBA 1RNIA 2PY8A 2QEXP 3CCQP 2Z45A 1E6JP 5BS1A 1YIJP 1M74A 2BUOA 4QNBA 4U0FA 1VQ7P 2EFJA 5HGOA 3DTJA 2ONTA 2PEIA 1VQLP 2XV6A 1Q86Q 3CCUP 2PENA 2Z46A 4GR6A 4COPA 3G0VA 3B5IA 3CCRP 3CC7P 1Q7YQ 4U0CA 1QVGO 1VQ4P 3LRYA 5BS2A 2KODA 3CPWO 3CCSP 1N8RQ 4PH0A 3G21A 4XFXA 1D1DA 2BHVA 1JJ2O 3WBHA 1IUQA 5JPAA 2E1MA 3DS2A 1M90Q 4WYMA 2OARA 1Q82Q 1VQ5P 1M6EX 3HZQA 3DS5A 1RO2A 5F2OA 2JYGA 5HGMA 3I55P 3CC2P 1VQ6P 3G29A 2XT1A 2PEQA 2CWOA 3G1GA 1EOQA 1YHQP 1S72P 2OTJP 4XROA 4U0BA 4PH1A 1EIAA 3OW2O 5I4TG 5HGLA 3DS4A 2M8NA 3P05A 4U0DA 1K8AQ 1ZMBA 3G1IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E6J P;  3DS0 A;  3G26 A;  4COC A;  5JPA A;  3DPH A;  4XFY A;  2BUO A;  4QNB A;  4U0F A;  4XFZ A;  4U0A A;  3DS2 A;  4IPY A;  1A8O A;  5HGO A;  4WYM A;  3DTJ A;  2ONT A;  5HGN A;  3H4E A;  5DCK A;  2EIA A;  3DS5 A;  2XV6 A;  3H47 A;  5HGM A;  2JYG A;  2JYL A;  2M8L A;  3G29 A;  3DS1 A;  2JO0 A;  2XT1 A;  4XRQ A;  1BAJ A;  2L6E A;  3G0V A;  3NTE A;  3G1G A;  1EOQ A;  4U0C A;  4COP A;  3LRY A;  4U0B A;  3DS3 A;  4U0E A;  4PH1 A;  2KOD A;  3G28 A;  3MGE A;  4XRO A;  4M0I A;  1EIA A;  3VRL C;  4PH0 A;  5I4T G;  5HGL A;  1QRJ A;  3DS4 A;  1D1D A;  2M8P A;  2M8N A;  3G21 A;  3P05 A;  2LF4 A;  2XXM A;  4U0D A;  1A43 A;  4XFX A;  3G1I A;  1AUM A; 
#chains in the Genus database with same CATH topology
 2AVA A;  2MF4 A;  3DS0 A;  4U0A A;  2GZJ A;  1A8O A;  3H4E A;  2DNW A;  2CGQ A;  1X3O A;  3I56 P;  1VQ9 P;  1YJN P;  1T8K A;  3G71 P;  4CA3 A;  2XXM A;  1YI2 P;  1A43 A;  1AUM A;  3CCL P;  2DGY A;  5EJD A;  2K2Q A;  5HV8 A;  2PEO A;  2LIU A;  4H2X C;  3CCM P;  1VQP P;  2P9X A;  1YIT P;  3NTE A;  7CEI A;  4BPF A;  1VHN A;  1KD1 Q;  1F80 D;  2JGP A;  3CCQ P;  5EW5 E;  2PNG A;  2EHT A;  1UNK A;  4F37 A;  2KOR A;  2ONT A;  2FVF A;  1Q86 Q;  3CCU P;  2VLN A;  4COP A;  2JU1 A;  3CC7 P;  2LIW A;  2LML A;  3CCS P;  4PH0 A;  1OR5 A;  1D1D A;  2K5X A;  2L0Q A;  2FVE A;  2BHV A;  4H2W C;  2GZG A;  2LTE A;  2E1M A;  2K0Y A;  3GJN A;  2OAR A;  1VQ5 P;  2FAE A;  2KOP A;  2JYG A;  3I55 P;  2VLO A;  3CC2 P;  1EOQ A;  4U0B A;  4PH1 A;  1EIA A;  5I4T G;  5HGL A;  1DV5 A;  3RG6 C;  2EG5 A;  1YJ9 P;  1UJZ A;  4DG9 A;  2MVV A;  3M1M A;  3CD6 P;  2KOO A;  1M1K Q;  5DCK A;  1ZNV A;  1VQO P;  3EJE A;  1BAJ A;  1M6N A;  1AYI A;  2L6E A;  4U0E A;  2VLQ A;  1QRJ A;  1VQM P;  3DPH A;  3CXC O;  2QA4 P;  2KG8 A;  2N5I A;  4IPY A;  3CCE P;  2FAD A;  1KQS O;  2JO0 A;  2L4B A;  3MGE A;  2MVU A;  2PY8 A;  2QEX P;  2Z45 A;  1M74 A;  4QNB A;  2FVA A;  2ERH A;  2K93 A;  2M5R A;  2PEI A;  2MY5 A;  5KP7 B;  3G0V A;  3CCR P;  2LOL A;  3CPW O;  1N8R Q;  2KOS A;  1NQ4 A;  4XFX A;  2CQ8 A;  2JU2 A;  1IUQ A;  4R0M A;  2CG5 B;  4WYM A;  2L9F A;  2ROQ A;  1Q82 Q;  5HGM A;  2L22 A;  1VQ6 P;  3G29 A;  1YHQ P;  3G1G A;  2OTJ P;  1S72 P;  2K0D X;  1K8A Q;  1ZMB A;  3GKL C;  2KG9 A;  2FQ1 A;  3CC4 P;  4XFZ A;  5F2N A;  1MZ8 A;  1FR2 A;  1KC8 Q;  3CME P;  3DS1 A;  3CCV P;  1W2B O;  2PEM A;  1CEI A;  2M8P A;  5KP8 B;  1VQN P;  1Z6M A;  2CNR A;  3G6E P;  5KP6 B;  2N98 A;  5HGN A;  2AF8 A;  1HQB A;  1EMV A;  3H47 A;  1VQ8 P;  1VQK P;  2MR7 A;  1L0I A;  1K73 Q;  1GXG A;  2Z44 A;  3RG2 A;  3G28 A;  1K9M Q;  4M0I A;  1GPJ A;  1L0H A;  3HYB A;  4NEO A;  1RNI A;  3EJB A;  2FQ0 A;  2EHS A;  1E6J P;  5BS1 A;  2NO8 A;  2KG6 A;  1DNY A;  2EFJ A;  4UHP B;  3DTJ A;  2XZ0 D;  3NY7 B;  2PEN A;  2GZI A;  4H2Y C;  1Q7Y Q;  4U0C A;  2GZF A;  1QVG O;  1VQ4 P;  3LRY A;  4MRT C;  3G21 A;  2KGC A;  1JJ2 O;  2K92 A;  5JPA A;  2LL8 A;  2GDY A;  3B4Q A;  3DS2 A;  1M90 Q;  2KGE A;  1AF8 A;  3DS5 A;  1RO2 A;  5F2O A;  4QKO A;  2N50 A;  2K0X A;  4XRO A;  3OW2 O;  2VSQ A;  2AFE A;  3P05 A;  4U0D A;  3G1I A;  1YJW P;  3CCJ P;  2FAC A;  1HY8 A;  5CZD B;  4GR2 A;  3E2D A;  2M8L A;  2LPK A;  3G4S P;  3H0D A;  2QNW A;  2GZE A;  5F2K A;  1KLP A;  2LF4 A;  1IMP A;  2WPT A;  1QVF O;  5HVC A;  2VLP A;  3DS3 A;  1NJI Q;  3Q20 A;  3G26 A;  4COC A;  1VKU A;  2X2B A;  1K30 A;  2KGD A;  2N6Z A;  4XFY A;  3GZM A;  3CMA P;  2KR5 A;  2EIA A;  3U43 A;  2JYL A;  4BPG A;  1RO0 A;  3VRL C;  4XRQ A;  2PEK A;  2OTL P;  2FQ2 A;  2PEJ A;  2XZ1 C;  1Q81 Q;  2JBG A;  2GDX A;  2MD9 A;  2N6Y A;  2N5H A;  1YIJ P;  3LMO A;  2BUO A;  4U0F A;  1VQ7 P;  1ACP A;  5HGO A;  1VQL P;  2XV6 A;  2Z46 A;  2KOQ A;  3GZL A;  4GR6 A;  4BPH A;  3B5I A;  2MR8 A;  5BS2 A;  2KOD A;  4IZ6 A;  3EJD A;  2FHS C;  4HKG A;  4PWV B;  1E0H A;  2JQ4 A;  3CE7 A;  3WBH A;  2GDW A;  2KWL A;  1IMQ A;  2KW2 A;  4PXH B;  1M6E X;  3HZQ A;  2JB0 A;  2XT1 A;  2GYK A;  2PEQ A;  1GXH A;  2CWO A;  2AFD A;  1BXI A;  2JAZ A;  2K94 A;  3DS4 A;  2M8N A;  2LKI A;  2KGA A; 
#chains in the Genus database with same CATH homology
 3RG6 C;  1YJW P;  3DS0 A;  2EG5 A;  1YJ9 P;  3CCJ P;  3M1M A;  3CD6 P;  3CC4 P;  4XFZ A;  4U0A A;  5F2N A;  1M1K Q;  1A8O A;  3H4E A;  5DCK A;  1KC8 Q;  4GR2 A;  3CME P;  1VQO P;  3E2D A;  2M8L A;  3DS1 A;  3G4S P;  1BAJ A;  1M6N A;  2L6E A;  4U0E A;  3H0D A;  3I56 P;  3CCV P;  1W2B O;  5F2K A;  2PEM A;  1YJN P;  1QRJ A;  3G71 P;  1VQ9 P;  2M8P A;  1VQN P;  2LF4 A;  2XXM A;  1YI2 P;  1QVF O;  3DS3 A;  1A43 A;  1NJI Q;  1AUM A;  3Q20 A;  3G26 A;  4COC A;  1VQM P;  2DGY A;  3CCL P;  3DPH A;  1K30 A;  3G6E P;  3CXC O;  4XFY A;  2QA4 P;  3CMA P;  4IPY A;  3CCE P;  5HGN A;  2PEO A;  2EIA A;  1KQS O;  1VQK P;  3CCM P;  3H47 A;  1VQP P;  1VQ8 P;  2JYL A;  2P9X A;  1YIT P;  1RO0 A;  3VRL C;  2JO0 A;  1K73 Q;  4XRQ A;  2Z44 A;  3NTE A;  2PEK A;  2OTL P;  2PEJ A;  1Q81 Q;  3G28 A;  3MGE A;  1K9M Q;  4M0I A;  1KD1 Q;  3HYB A;  1RNI A;  2PY8 A;  2QEX P;  3CCQ P;  2Z45 A;  1E6J P;  5BS1 A;  1YIJ P;  1M74 A;  2BUO A;  4QNB A;  4U0F A;  1VQ7 P;  2EFJ A;  5HGO A;  3DTJ A;  2ONT A;  2PEI A;  1VQL P;  2XV6 A;  1Q86 Q;  3CCU P;  2PEN A;  2Z46 A;  4GR6 A;  4COP A;  3G0V A;  3B5I A;  3CCR P;  3CC7 P;  1Q7Y Q;  4U0C A;  1QVG O;  1VQ4 P;  3LRY A;  5BS2 A;  2KOD A;  3CPW O;  3CCS P;  1N8R Q;  4PH0 A;  3G21 A;  4XFX A;  1D1D A;  2BHV A;  1JJ2 O;  3WBH A;  1IUQ A;  5JPA A;  2E1M A;  3DS2 A;  1M90 Q;  4WYM A;  2OAR A;  1Q82 Q;  1VQ5 P;  1M6E X;  3HZQ A;  3DS5 A;  1RO2 A;  5F2O A;  2JYG A;  5HGM A;  3I55 P;  3CC2 P;  1VQ6 P;  3G29 A;  2XT1 A;  2PEQ A;  2CWO A;  3G1G A;  1EOQ A;  1YHQ P;  1S72 P;  2OTJ P;  4XRO A;  4U0B A;  4PH1 A;  1EIA A;  3OW2 O;  5I4T G;  5HGL A;  3DS4 A;  2M8N A;  3P05 A;  4U0D A;  1K8A Q;  1ZMB A;  3G1I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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