2L6EA

Nmr structure of the monomeric mutant c-terminal domain of hiv-1 capsid in complex with stapled peptide inhibitor
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
94
structure length
94
Chain Sequence
SGLVPRGSHMTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNAATETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution structure of a hydrocarbon stapled peptide inhibitor in complex with monomeric C-terminal domain of HIV-1 capsid.
pubmed doi rcsb
molecule tags Viral protein/inhibitor
source organism Human immunodeficiency virus 1
molecule keywords Capsid protein p24
total genus 28
structure length 94
sequence length 94
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2010-11-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.30 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A 2l6eA00
3DS1A 2L6EA 3DS3A 3MGEA 4WYMA 5HGOA 2LF4A 3G26A 3G0VA 5DCKA 3G29A 1E6JP 2XV6A 1A43A 4PH1A 4U0CA 4XFXA 4M0IA 3NTEA 4U0DA 4XFZA 2M8LA 1EIAA 3VRLC 2JYLA 5HGMA 4COPA 3DS0A 4PH0A 5HGNA 4U0EA 2ONTA 3G28A 5JPAA 3G1IA 2JYGA 2JO0A 4XRQA 2XXMA 4IPYA 2XT1A 3H4EA 3DTJA 4U0BA 4XROA 3DS4A 4U0AA 1D1DA 1EOQA 3DPHA 3DS5A 2M8NA 3P05A 5HGLA 1QRJA 4U0FA 3G21A 3DS2A 3H47A 2BUOA 4COCA 3LRYA 4XFYA 1BAJA 4QNBA 2M8PA 1A8OA 5I4TG 1AUMA 3G1GA 2EIAA 2KODA
chains in the Genus database with same CATH superfamily
1VQ5P 4H2YC 2GZIA 2FVEA 2FVAA 2LMLA 2K94A 2FQ2A 1QVFO 2PY8A 2CQ8A 2FHSC 3DS4A 4H2WC 2CG5B 1YJ9P 4U0FA 3G21A 2Z44A 2VLOA 2BUOA 3CCLP 2DGYA 2EIAA 2FQ0A 1ACPA 3MGEA 1Z6MA 2K92A 2QEXP 4UHPB 4MRTC 1EIAA 1VQ9P 2KOQA 4U0EA 3HYBA 2QNWA 4PWVB 1HQBA 1IMPA 3RG2A 4R0MA 1KC8Q 1BAJA 3LMOA 2JAZA 1IMQA 3CE7A 1VQKP 3G26A 2KOPA 2K0DX 2DNWA 2ROQA 2PEIA 2JU2A 1RO2A 2WPTA 2LKIA 3LRYA 4XFYA 4QKOA 1KD1Q 1A8OA 3G1GA 2FVFA 2KODA 2PEOA 1VQ8P 1NQ4A 2N6YA 2MY5A 2ERHA 4XFXA 2LPKA 3GZLA 2AFEA 3GKLC 2XXMA 1VQNP 2KGEA 2GDXA 5HGLA 3H0DA 1VHNA 1Q81Q 2PEQA 1VQOP 1VQMP 3DS3A 2GZGA 3CMAP 5CZDB 3RG6C 1E6JP 1A43A 3CCQP 2JGPA 3DS0A 2LIUA 1NJIQ 2EHTA 2FADA 2KWLA 1HY8A 1DNYA 1GXHA 2FACA 1X3OA 1Q86Q 3CC2P 2L6EA 2QA4P 2OTJP 2M5RA 2LF4A 1OR5A 3E2DA 1YJWP 3G29A 5HVCA 1KQSO 1JJ2O 5JPAA 2N5IA 2JO0A 2K2QA 2GZEA 2PEKA 1VQ7P 1L0IA 4PXHB 3CCEP 1YIJP 3DS2A 2PENA 1L0HA 2KGDA 1AUMA 1M1KQ 2Z45A 2MD9A 2N98A 3VRLC 2N50A 2N5HA 2XT1A 2FQ1A 1E0HA 2P9XA 1YI2P 3CPWO 1ZMBA 3G6EP 3CMEP 1RO0A 1M90Q 3DS1A 2L4BA 3CCRP 2LOLA 2KW2A 3EJDA 4U0CA 3NTEA 1UJZA 2KGAA 1YJNP 1DV5A 2EG5A 4XROA 2M8NA 2K5XA 1YHQP 1VQ6P 3B4QA 1K8AQ 2VLNA 5EJDA 2KG8A 2JBGA 1KLPA 2E1MA 1UNKA 2CWOA 1W2BO 3Q20A 2K0XA 3CC4P 3CCJP 3DS5A 1IUQA 4GR2A 1M6NA 2L9FA 2GYKA 2KORA 3WBHA 1VQ4P 1BXIA 4WYMA 1GPJA 2VLQA 3EJEA 4COPA 5HGMA 5F2OA 1VQPP 3G1IA 2KGCA 5KP7B 3U43A 5KP6B 2NO8A 5HV8A 4COCA 5BS2A 4QNBA 1RNIA 3M1MA 1FR2A 2L0QA 2OTLP 2KR5A 2Z46A 2MVVA 2JYLA 1M6EX 4H2XC 3CCSP 2JYGA 5BS1A 3G71P 3DTJA 3CC7P 3P05A 2XZ1C 5EW5E 2KOSA 3CD6P 1N8RQ 1YITP 2M8PA 2MF4A 5F2KA 3CXCO 1VQLP 2AVAA 4F37A 4DG9A 4GR6A 2KG9A 3GZMA 2VLPA 2OARA 2ONTA 2MR7A 1VKUA 4IPYA 3H4EA 3I56P 2CNRA 4U0AA 2L22A 5KP8B 3HZQA 2MVUA 4IZ6A 1Q7YQ 4BPFA 5HGNA 1K73Q 2LIWA 1K9MQ 3G4SP 2GZFA 5DCKA 2KOOA 2K0YA 2X2BA 1Q82Q 3NY7B 3CCVP 1D1DA 3DPHA 5F2NA 2PEMA 5I4TG 2FAEA 1GXGA 2XZ0D 3G0VA 1AYIA 2PEJA 2N6ZA 1AF8A 1T8KA 2BHVA 4XRQA 1ZNVA 2AFDA 2AF8A 1CEIA 3CCMP 4NEOA 1M74A 2GDYA 2PNGA 5HGOA 1F80D 1MZ8A 2JQ4A 2K93A 2LL8A 2KG6A 2XV6A 2GZJA 2JB0A 4XFZA 4U0DA 4BPHA 1S72P 2VSQA 1QVGO 4U0BA 1EOQA 3OW2O 2EHSA 4HKGA 7CEIA 3B5IA 2MR8A 4BPGA 3GJNA 2CGQA 1EMVA 3I55P 3CCUP 2M8LA 4M0IA 3EJBA 4PH0A 3G28A 2LTEA 2JU1A 1K30A 2EFJA 1QRJA 3H47A 4PH1A 4CA3A 2GDWA
chains in the Genus database with same CATH topology
1K73Q 3DS3A 1VQ5P 2E1MA 1K9MQ 3CMAP 3G4SP 5DCKA 3RG6C 1E6JP 1A43A 1Q82Q 3CCQP 2CWOA 1W2BO 3Q20A 3DS0A 1NJIQ 3CC4P 3CCJP 1QVFO 2PY8A 3CCVP 1D1DA 3DS4A 3DPHA 3DS5A 5F2NA 1YJ9P 1IUQA 2PEMA 3G21A 4U0FA 2Z44A 2BUOA 4GR2A 1M6NA 3CCLP 5I4TG 3WBHA 2DGYA 2EIAA 1VQ4P 1Q86Q 3CC2P 2L6EA 2QA4P 4WYMA 3MGEA 2OTJP 2QEXP 2LF4A 3E2DA 3G0VA 1YJWP 2PEJA 3G29A 1KQSO 1EIAA 4COPA 5HGMA 1JJ2O 5JPAA 5F2OA 1VQPP 4U0EA 1VQ9P 3HYBA 3G1IA 2BHVA 2JO0A 4XRQA 2PEKA 1VQ7P 3CCEP 3CCMP 1YIJP 3DS2A 4COCA 1KC8Q 1BAJA 5BS2A 2PENA 4QNBA 1M74A 1RNIA 3M1MA 1AUMA 1M1KQ 5HGOA 1VQKP 3G26A 2Z45A 2OTLP 2Z46A 2XV6A 4XFZA 4U0DA 3VRLC 2PEIA 2JYLA 1M6EX 3CCSP 1S72P 2JYGA 5BS1A 3G71P 1QVGO 2XT1A 3DTJA 4U0BA 3CC7P 1RO2A 1EOQA 3P05A 3OW2O 3CD6P 2P9XA 1YI2P 3CPWO 1ZMBA 3LRYA 4XFYA 1N8RQ 1YITP 2M8PA 1KD1Q 1A8OA 3G6EP 3CMEP 5F2KA 3CXCO 3G1GA 3B5IA 1RO0A 1VQLP 2KODA 1M90Q 3DS1A 3CCRP 2PEOA 1VQ8P 4GR6A 4U0CA 4XFXA 4M0IA 3NTEA 2M8LA 4PH0A 3I55P 3CCUP 1YJNP 2OARA 2ONTA 3G28A 2EG5A 2XXMA 4IPYA 3H4EA 4XROA 3I56P 1K30A 2EFJA 4U0AA 1VQNP 2M8NA 3HZQA 1YHQP 5HGLA 1VQ6P 3H0DA 1QRJA 1Q81Q 3H47A 1K8AQ 2PEQA 1VQOP 1VQMP 1Q7YQ 4PH1A 5HGNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DS1 A;  2L6E A;  3DS3 A;  3MGE A;  4WYM A;  5HGO A;  2LF4 A;  3G26 A;  3G0V A;  5DCK A;  3G29 A;  1E6J P;  2XV6 A;  1A43 A;  4PH1 A;  4U0C A;  4XFX A;  4M0I A;  3NTE A;  4U0D A;  4XFZ A;  2M8L A;  1EIA A;  3VRL C;  2JYL A;  5HGM A;  4COP A;  3DS0 A;  4PH0 A;  5HGN A;  4U0E A;  2ONT A;  3G28 A;  5JPA A;  3G1I A;  2JYG A;  2JO0 A;  4XRQ A;  2XXM A;  4IPY A;  2XT1 A;  3H4E A;  3DTJ A;  4U0B A;  4XRO A;  3DS4 A;  4U0A A;  1D1D A;  1EOQ A;  3DPH A;  3DS5 A;  2M8N A;  3P05 A;  5HGL A;  1QRJ A;  4U0F A;  3G21 A;  3DS2 A;  3H47 A;  2BUO A;  4COC A;  3LRY A;  4XFY A;  1BAJ A;  4QNB A;  2M8P A;  1A8O A;  5I4T G;  1AUM A;  3G1G A;  2EIA A;  2KOD A; 
#chains in the Genus database with same CATH topology
 1VQ5 P;  4H2Y C;  2GZI A;  2FVE A;  2FVA A;  2LML A;  2K94 A;  2FQ2 A;  1QVF O;  2PY8 A;  2CQ8 A;  2FHS C;  3DS4 A;  4H2W C;  2CG5 B;  1YJ9 P;  4U0F A;  3G21 A;  2Z44 A;  2VLO A;  2BUO A;  3CCL P;  2DGY A;  2EIA A;  2FQ0 A;  1ACP A;  3MGE A;  1Z6M A;  2K92 A;  2QEX P;  4UHP B;  4MRT C;  1EIA A;  1VQ9 P;  2KOQ A;  4U0E A;  3HYB A;  2QNW A;  4PWV B;  1HQB A;  1IMP A;  3RG2 A;  4R0M A;  1KC8 Q;  1BAJ A;  3LMO A;  2JAZ A;  1IMQ A;  3CE7 A;  1VQK P;  3G26 A;  2KOP A;  2K0D X;  2DNW A;  2ROQ A;  2PEI A;  2JU2 A;  1RO2 A;  2WPT A;  2LKI A;  3LRY A;  4XFY A;  4QKO A;  1KD1 Q;  1A8O A;  3G1G A;  2FVF A;  2KOD A;  2PEO A;  1VQ8 P;  1NQ4 A;  2N6Y A;  2MY5 A;  2ERH A;  4XFX A;  2LPK A;  3GZL A;  2AFE A;  3GKL C;  2XXM A;  1VQN P;  2KGE A;  2GDX A;  5HGL A;  3H0D A;  1VHN A;  1Q81 Q;  2PEQ A;  1VQO P;  1VQM P;  3DS3 A;  2GZG A;  3CMA P;  5CZD B;  3RG6 C;  1E6J P;  1A43 A;  3CCQ P;  2JGP A;  3DS0 A;  2LIU A;  1NJI Q;  2EHT A;  2FAD A;  2KWL A;  1HY8 A;  1DNY A;  1GXH A;  2FAC A;  1X3O A;  1Q86 Q;  3CC2 P;  2L6E A;  2QA4 P;  2OTJ P;  2M5R A;  2LF4 A;  1OR5 A;  3E2D A;  1YJW P;  3G29 A;  5HVC A;  1KQS O;  1JJ2 O;  5JPA A;  2N5I A;  2JO0 A;  2K2Q A;  2GZE A;  2PEK A;  1VQ7 P;  1L0I A;  4PXH B;  3CCE P;  1YIJ P;  3DS2 A;  2PEN A;  1L0H A;  2KGD A;  1AUM A;  1M1K Q;  2Z45 A;  2MD9 A;  2N98 A;  3VRL C;  2N50 A;  2N5H A;  2XT1 A;  2FQ1 A;  1E0H A;  2P9X A;  1YI2 P;  3CPW O;  1ZMB A;  3G6E P;  3CME P;  1RO0 A;  1M90 Q;  3DS1 A;  2L4B A;  3CCR P;  2LOL A;  2KW2 A;  3EJD A;  4U0C A;  3NTE A;  1UJZ A;  2KGA A;  1YJN P;  1DV5 A;  2EG5 A;  4XRO A;  2M8N A;  2K5X A;  1YHQ P;  1VQ6 P;  3B4Q A;  1K8A Q;  2VLN A;  5EJD A;  2KG8 A;  2JBG A;  1KLP A;  2E1M A;  1UNK A;  2CWO A;  1W2B O;  3Q20 A;  2K0X A;  3CC4 P;  3CCJ P;  3DS5 A;  1IUQ A;  4GR2 A;  1M6N A;  2L9F A;  2GYK A;  2KOR A;  3WBH A;  1VQ4 P;  1BXI A;  4WYM A;  1GPJ A;  2VLQ A;  3EJE A;  4COP A;  5HGM A;  5F2O A;  1VQP P;  3G1I A;  2KGC A;  5KP7 B;  3U43 A;  5KP6 B;  2NO8 A;  5HV8 A;  4COC A;  5BS2 A;  4QNB A;  1RNI A;  3M1M A;  1FR2 A;  2L0Q A;  2OTL P;  2KR5 A;  2Z46 A;  2MVV A;  2JYL A;  1M6E X;  4H2X C;  3CCS P;  2JYG A;  5BS1 A;  3G71 P;  3DTJ A;  3CC7 P;  3P05 A;  2XZ1 C;  5EW5 E;  2KOS A;  3CD6 P;  1N8R Q;  1YIT P;  2M8P A;  2MF4 A;  5F2K A;  3CXC O;  1VQL P;  2AVA A;  4F37 A;  4DG9 A;  4GR6 A;  2KG9 A;  3GZM A;  2VLP A;  2OAR A;  2ONT A;  2MR7 A;  1VKU A;  4IPY A;  3H4E A;  3I56 P;  2CNR A;  4U0A A;  2L22 A;  5KP8 B;  3HZQ A;  2MVU A;  4IZ6 A;  1Q7Y Q;  4BPF A;  5HGN A;  1K73 Q;  2LIW A;  1K9M Q;  3G4S P;  2GZF A;  5DCK A;  2KOO A;  2K0Y A;  2X2B A;  1Q82 Q;  3NY7 B;  3CCV P;  1D1D A;  3DPH A;  5F2N A;  2PEM A;  5I4T G;  2FAE A;  1GXG A;  2XZ0 D;  3G0V A;  1AYI A;  2PEJ A;  2N6Z A;  1AF8 A;  1T8K A;  2BHV A;  4XRQ A;  1ZNV A;  2AFD A;  2AF8 A;  1CEI A;  3CCM P;  4NEO A;  1M74 A;  2GDY A;  2PNG A;  5HGO A;  1F80 D;  1MZ8 A;  2JQ4 A;  2K93 A;  2LL8 A;  2KG6 A;  2XV6 A;  2GZJ A;  2JB0 A;  4XFZ A;  4U0D A;  4BPH A;  1S72 P;  2VSQ A;  1QVG O;  4U0B A;  1EOQ A;  3OW2 O;  2EHS A;  4HKG A;  7CEI A;  3B5I A;  2MR8 A;  4BPG A;  3GJN A;  2CGQ A;  1EMV A;  3I55 P;  3CCU P;  2M8L A;  4M0I A;  3EJB A;  4PH0 A;  3G28 A;  2LTE A;  2JU1 A;  1K30 A;  2EFJ A;  1QRJ A;  3H47 A;  4PH1 A;  4CA3 A;  2GDW A; 
#chains in the Genus database with same CATH homology
 1K73 Q;  3DS3 A;  1VQ5 P;  2E1M A;  1K9M Q;  3CMA P;  3G4S P;  5DCK A;  3RG6 C;  1E6J P;  1A43 A;  1Q82 Q;  3CCQ P;  2CWO A;  1W2B O;  3Q20 A;  3DS0 A;  1NJI Q;  3CC4 P;  3CCJ P;  1QVF O;  2PY8 A;  3CCV P;  1D1D A;  3DS4 A;  3DPH A;  3DS5 A;  5F2N A;  1YJ9 P;  1IUQ A;  2PEM A;  3G21 A;  4U0F A;  2Z44 A;  2BUO A;  4GR2 A;  1M6N A;  3CCL P;  5I4T G;  3WBH A;  2DGY A;  2EIA A;  1VQ4 P;  1Q86 Q;  3CC2 P;  2L6E A;  2QA4 P;  4WYM A;  3MGE A;  2OTJ P;  2QEX P;  2LF4 A;  3E2D A;  3G0V A;  1YJW P;  2PEJ A;  3G29 A;  1KQS O;  1EIA A;  4COP A;  5HGM A;  1JJ2 O;  5JPA A;  5F2O A;  1VQP P;  4U0E A;  1VQ9 P;  3HYB A;  3G1I A;  2BHV A;  2JO0 A;  4XRQ A;  2PEK A;  1VQ7 P;  3CCE P;  3CCM P;  1YIJ P;  3DS2 A;  4COC A;  1KC8 Q;  1BAJ A;  5BS2 A;  2PEN A;  4QNB A;  1M74 A;  1RNI A;  3M1M A;  1AUM A;  1M1K Q;  5HGO A;  1VQK P;  3G26 A;  2Z45 A;  2OTL P;  2Z46 A;  2XV6 A;  4XFZ A;  4U0D A;  3VRL C;  2PEI A;  2JYL A;  1M6E X;  3CCS P;  1S72 P;  2JYG A;  5BS1 A;  3G71 P;  1QVG O;  2XT1 A;  3DTJ A;  4U0B A;  3CC7 P;  1RO2 A;  1EOQ A;  3P05 A;  3OW2 O;  3CD6 P;  2P9X A;  1YI2 P;  3CPW O;  1ZMB A;  3LRY A;  4XFY A;  1N8R Q;  1YIT P;  2M8P A;  1KD1 Q;  1A8O A;  3G6E P;  3CME P;  5F2K A;  3CXC O;  3G1G A;  3B5I A;  1RO0 A;  1VQL P;  2KOD A;  1M90 Q;  3DS1 A;  3CCR P;  2PEO A;  1VQ8 P;  4GR6 A;  4U0C A;  4XFX A;  4M0I A;  3NTE A;  2M8L A;  4PH0 A;  3I55 P;  3CCU P;  1YJN P;  2OAR A;  2ONT A;  3G28 A;  2EG5 A;  2XXM A;  4IPY A;  3H4E A;  4XRO A;  3I56 P;  1K30 A;  2EFJ A;  4U0A A;  1VQN P;  2M8N A;  3HZQ A;  1YHQ P;  5HGL A;  1VQ6 P;  3H0D A;  1QRJ A;  1Q81 Q;  3H47 A;  1K8A Q;  2PEQ A;  1VQO P;  1VQM P;  1Q7Y Q;  4PH1 A;  5HGN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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