2XV6A

Crystal structure of the hiv-1 capsid protein c-terminal domain (146- 220) in complex with a camelid vhh.
Total Genus 28
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
75
structure length
75
Chain Sequence
SPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPGATLEEMMTACQG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors
rcsb
molecule tags Viral protein/immune system
source organism Human immunodeficiency virus 1
molecule keywords CAPSID PROTEIN P24
total genus 28
structure length 75
sequence length 75
chains with identical sequence C
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2010-10-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.30 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A 2xv6A00
3G0VA 3G28A 5HGOA 4WYMA 2XV6A 3DTJA 3G1GA 4U0CA 4PH0A 3DS0A 2KODA 1QRJA 1BAJA 4IPYA 1EOQA 2M8LA 5HGLA 2XXMA 1D1DA 4PH1A 5HGNA 4U0DA 5HGMA 1EIAA 2M8NA 4XROA 4XFZA 3G1IA 1A8OA 3DS5A 3MGEA 3G26A 3DS1A 4U0BA 4QNBA 3DS2A 1E6JP 4U0AA 5JPAA 4XRQA 1AUMA 2LF4A 3G29A 2JO0A 3DS4A 2BUOA 2ONTA 3DS3A 5DCKA 1A43A 4M0IA 4COPA 2L6EA 3LRYA 2JYGA 4U0EA 3DPHA 3G21A 3P05A 4XFXA 2XT1A 4U0FA 4XFYA 2EIAA 2JYLA 2M8PA 3VRLC 3NTEA 3H47A 5I4TG 4COCA 3H4EA
chains in the Genus database with same CATH superfamily
4CA3A 3OW2O 1M90Q 5HVCA 3DS0A 2VLPA 4MRTC 1T8KA 2M8NA 3DS5A 1L0HA 2AF8A 1ZMBA 5JPAA 1MZ8A 3CCEP 1YIJP 2PEQA 2FACA 4PH1A 2JQ4A 1M6EX 4XFZA 2N98A 4HKGA 2FQ2A 4U0AA 1JJ2O 2DNWA 1L0IA 1KC8Q 3U43A 2JAZA 2EHTA 5F2KA 4XRQA 3M1MA 3NTEA 1VQ4P 3G0VA 3G6EP 3NY7B 2FQ1A 2GDYA 1YI2P 5CZDB 2JO0A 4R0MA 2MR8A 2VLNA 3EJBA 2K0DX 4BPFA 5KP7B 2EIAA 1YJWP 4H2WC 3B5IA 1YJ9P 1VQNP 1EOQA 2AFDA 1EIAA 1OR5A 3G1IA 3MGEA 2GDWA 3CMEP 3DS1A 1GXHA 2K0XA 2KG9A 1M74A 2N5IA 3CC7P 2CWOA 1AUMA 1Q86Q 1YITP 2LIUA 1VQ7P 3LRYA 4XFXA 1VQ8P 1ZNVA 2LKIA 3P05A 3LMOA 4H2YC 2QEXP 2JYLA 1GPJA 1E0HA 1VQ6P 3G71P 1NQ4A 4PXHB 2Z46A 3Q20A 2FADA 1RO2A 2NO8A 2PEMA 3DPHA 1VQKP 2XZ0D 1NJIQ 3CD6P 1YHQP 1D1DA 2JU2A 3GZMA 5HGMA 2XZ1C 2CQ8A 1IUQA 1IMQA 2MR7A 2ROQA 2M5RA 2CNRA 2FAEA 2Z44A 2AFEA 2MVUA 2N6ZA 2KOPA 4U0EA 1BXIA 3H47A 2PENA 2DGYA 1A8OA 3RG2A 3EJEA 1UJZA 3G4SP 2KGAA 3DS2A 2EG5A 1E6JP 2OARA 2GYKA 4DG9A 3DS3A 4M0IA 5EW5E 2XT1A 1AF8A 2M8PA 2PNGA 2L22A 1VQ5P 1KD1Q 2L9FA 2PY8A 2JGPA 2KR5A 4XROA 2K0YA 5F2NA 1Q81Q 2KW2A 4BPGA 2MF4A 3RG6C 2E1MA 3CCJP 3H0DA 4IZ6A 1W2BO 4IPYA 1CEIA 2LIWA 1VQMP 2VLQA 5EJDA 2BUOA 5BS1A 3CE7A 1K73Q 1AYIA 3H4EA 2XV6A 1VQLP 3E2DA 2KGEA 5KP6B 2JB0A 2K5XA 3B4QA 3CCRP 7CEIA 4GR6A 3CXCO 1Z6MA 1GXGA 2OTJP 2JBGA 1EMVA 2Z45A 2QA4P 3CCMP 2PEKA 4XFYA 3VRLC 5I4TG 1UNKA 3CC4P 3G28A 3CCVP 3WBHA 4NEOA 2KWLA 2OTLP 2K94A 1QVFO 2N50A 3G26A 1S72P 2PEOA 1RNIA 2K2QA 2K92A 1HY8A 2FQ0A 2N6YA 3CCQP 2KGDA 5HGOA 4U0CA 2PEJA 4PWVB 5KP8B 1X3OA 1KLPA 4U0BA 2N5HA 2MVVA 3G29A 2QNWA 3CPWO 3CCSP 2LL8A 2LMLA 1VQPP 1F80D 2FVFA 3GZLA 4PH0A 2KODA 2KORA 1M6NA 2VSQA 2KOSA 1K9MQ 2KG8A 2PEIA 3CCUP 2EHSA 2LOLA 1Q82Q 2CGQA 3DS4A 2ONTA 4H2XC 5BS2A 1A43A 5F2OA 2LPKA 2GZJA 3I55P 4COCA 1VQOP 1K8AQ 1KQSO 3CMAP 2LTEA 3GJNA 1VHNA 3HZQA 1BAJA 1IMPA 2CG5B 2XXMA 5HGNA 4U0DA 2WPTA 2EFJA 2GZFA 3CC2P 5HV8A 2GDXA 1DNYA 2KGCA 2LF4A 4UHPB 2X2BA 1VQ9P 2L6EA 1K30A 3G21A 1HQBA 1Q7YQ 2L4BA 3DTJA 3G1GA 2GZGA 1ACPA 1QRJA 5HGLA 4F37A 2ERHA 2GZEA 2FHSC 4GR2A 1QVGO 2KG6A 4QNBA 1DV5A 3HYBA 3GKLC 5DCKA 1YJNP 3I56P 2KOOA 2JYGA 2GZIA 2L0QA 4U0FA 3CCLP 1N8RQ 4WYMA 1FR2A 2M8LA 2FVEA 2AVAA 2BHVA 2JU1A 2K93A 4QKOA 4BPHA 2MY5A 2KOQA 2P9XA 1VKUA 2VLOA 2MD9A 4COPA 2FVAA 1M1KQ 1RO0A 3EJDA
chains in the Genus database with same CATH topology
3CCJP 3OW2O 3H0DA 1M90Q 4PH0A 3DS0A 2KODA 1W2BO 4IPYA 1VQ6P 1M6NA 1K9MQ 3G71P 2M8NA 1VQMP 3DS5A 2PEIA 3CCUP 2Z46A 1Q82Q 3Q20A 3DS4A 1ZMBA 2BUOA 2ONTA 5BS1A 5BS2A 1RO2A 1A43A 5F2OA 2PEMA 5JPAA 3DPHA 4COCA 3I55P 1VQOP 1K73Q 1VQKP 3CCEP 1K8AQ 1YIJP 1KQSO 2PEQA 3H4EA 3CMAP 2XV6A 1VQLP 3HZQA 1BAJA 3E2DA 1NJIQ 3CD6P 1YHQP 2XXMA 1D1DA 4PH1A 5HGNA 4U0DA 5HGMA 1M6EX 2EFJA 4XFZA 1IUQA 3CCRP 4GR6A 3CXCO 3CC2P 4U0AA 1JJ2O 1KC8Q 2LF4A 2Z44A 2OTJP 2QA4P 2Z45A 1VQ9P 3CCMP 2L6EA 1K30A 2PEKA 5F2KA 4U0EA 4XRQA 3G21A 4XFYA 3M1MA 3VRLC 3NTEA 3H47A 5I4TG 2PENA 1VQ4P 3G0VA 1Q7YQ 3G28A 3CC4P 3DTJA 3G1GA 3CCVP 3G6EP 1QRJA 3WBHA 5HGLA 2DGYA 1YI2P 2OTLP 1QVFO 1A8OA 4GR2A 1QVGO 3G4SP 3G26A 4QNBA 1S72P 3DS2A 2EG5A 1E6JP 2PEOA 2OARA 3HYBA 1RNIA 2JO0A 3DS3A 5DCKA 1YJNP 3I56P 4M0IA 2JYGA 2XT1A 4U0FA 2EIAA 2M8PA 1YJWP 3CCLP 1N8RQ 1VQ5P 3CCQP 1KD1Q 5HGOA 4WYMA 4U0CA 3B5IA 1YJ9P 2PY8A 2M8LA 1VQNP 1EOQA 2BHVA 2PEJA 1EIAA 4XROA 3G1IA 3MGEA 5F2NA 3CMEP 3DS1A 4U0BA 1Q81Q 1M74A 3CC7P 2CWOA 2P9XA 1AUMA 3G29A 1Q86Q 1YITP 3CPWO 3RG6C 1VQ7P 4COPA 3LRYA 4XFXA 1VQ8P 1M1KQ 3P05A 2QEXP 3CCSP 2E1MA 2JYLA 1RO0A 1VQPP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G0V A;  3G28 A;  5HGO A;  4WYM A;  2XV6 A;  3DTJ A;  3G1G A;  4U0C A;  4PH0 A;  3DS0 A;  2KOD A;  1QRJ A;  1BAJ A;  4IPY A;  1EOQ A;  2M8L A;  5HGL A;  2XXM A;  1D1D A;  4PH1 A;  5HGN A;  4U0D A;  5HGM A;  1EIA A;  2M8N A;  4XRO A;  4XFZ A;  3G1I A;  1A8O A;  3DS5 A;  3MGE A;  3G26 A;  3DS1 A;  4U0B A;  4QNB A;  3DS2 A;  1E6J P;  4U0A A;  5JPA A;  4XRQ A;  1AUM A;  2LF4 A;  3G29 A;  2JO0 A;  3DS4 A;  2BUO A;  2ONT A;  3DS3 A;  5DCK A;  1A43 A;  4M0I A;  4COP A;  2L6E A;  3LRY A;  2JYG A;  4U0E A;  3DPH A;  3G21 A;  3P05 A;  4XFX A;  2XT1 A;  4U0F A;  4XFY A;  2EIA A;  2JYL A;  2M8P A;  3VRL C;  3NTE A;  3H47 A;  5I4T G;  4COC A;  3H4E A; 
#chains in the Genus database with same CATH topology
 4CA3 A;  3OW2 O;  1M90 Q;  5HVC A;  3DS0 A;  2VLP A;  4MRT C;  1T8K A;  2M8N A;  3DS5 A;  1L0H A;  2AF8 A;  1ZMB A;  5JPA A;  1MZ8 A;  3CCE P;  1YIJ P;  2PEQ A;  2FAC A;  4PH1 A;  2JQ4 A;  1M6E X;  4XFZ A;  2N98 A;  4HKG A;  2FQ2 A;  4U0A A;  1JJ2 O;  2DNW A;  1L0I A;  1KC8 Q;  3U43 A;  2JAZ A;  2EHT A;  5F2K A;  4XRQ A;  3M1M A;  3NTE A;  1VQ4 P;  3G0V A;  3G6E P;  3NY7 B;  2FQ1 A;  2GDY A;  1YI2 P;  5CZD B;  2JO0 A;  4R0M A;  2MR8 A;  2VLN A;  3EJB A;  2K0D X;  4BPF A;  5KP7 B;  2EIA A;  1YJW P;  4H2W C;  3B5I A;  1YJ9 P;  1VQN P;  1EOQ A;  2AFD A;  1EIA A;  1OR5 A;  3G1I A;  3MGE A;  2GDW A;  3CME P;  3DS1 A;  1GXH A;  2K0X A;  2KG9 A;  1M74 A;  2N5I A;  3CC7 P;  2CWO A;  1AUM A;  1Q86 Q;  1YIT P;  2LIU A;  1VQ7 P;  3LRY A;  4XFX A;  1VQ8 P;  1ZNV A;  2LKI A;  3P05 A;  3LMO A;  4H2Y C;  2QEX P;  2JYL A;  1GPJ A;  1E0H A;  1VQ6 P;  3G71 P;  1NQ4 A;  4PXH B;  2Z46 A;  3Q20 A;  2FAD A;  1RO2 A;  2NO8 A;  2PEM A;  3DPH A;  1VQK P;  2XZ0 D;  1NJI Q;  3CD6 P;  1YHQ P;  1D1D A;  2JU2 A;  3GZM A;  5HGM A;  2XZ1 C;  2CQ8 A;  1IUQ A;  1IMQ A;  2MR7 A;  2ROQ A;  2M5R A;  2CNR A;  2FAE A;  2Z44 A;  2AFE A;  2MVU A;  2N6Z A;  2KOP A;  4U0E A;  1BXI A;  3H47 A;  2PEN A;  2DGY A;  1A8O A;  3RG2 A;  3EJE A;  1UJZ A;  3G4S P;  2KGA A;  3DS2 A;  2EG5 A;  1E6J P;  2OAR A;  2GYK A;  4DG9 A;  3DS3 A;  4M0I A;  5EW5 E;  2XT1 A;  1AF8 A;  2M8P A;  2PNG A;  2L22 A;  1VQ5 P;  1KD1 Q;  2L9F A;  2PY8 A;  2JGP A;  2KR5 A;  4XRO A;  2K0Y A;  5F2N A;  1Q81 Q;  2KW2 A;  4BPG A;  2MF4 A;  3RG6 C;  2E1M A;  3CCJ P;  3H0D A;  4IZ6 A;  1W2B O;  4IPY A;  1CEI A;  2LIW A;  1VQM P;  2VLQ A;  5EJD A;  2BUO A;  5BS1 A;  3CE7 A;  1K73 Q;  1AYI A;  3H4E A;  2XV6 A;  1VQL P;  3E2D A;  2KGE A;  5KP6 B;  2JB0 A;  2K5X A;  3B4Q A;  3CCR P;  7CEI A;  4GR6 A;  3CXC O;  1Z6M A;  1GXG A;  2OTJ P;  2JBG A;  1EMV A;  2Z45 A;  2QA4 P;  3CCM P;  2PEK A;  4XFY A;  3VRL C;  5I4T G;  1UNK A;  3CC4 P;  3G28 A;  3CCV P;  3WBH A;  4NEO A;  2KWL A;  2OTL P;  2K94 A;  1QVF O;  2N50 A;  3G26 A;  1S72 P;  2PEO A;  1RNI A;  2K2Q A;  2K92 A;  1HY8 A;  2FQ0 A;  2N6Y A;  3CCQ P;  2KGD A;  5HGO A;  4U0C A;  2PEJ A;  4PWV B;  5KP8 B;  1X3O A;  1KLP A;  4U0B A;  2N5H A;  2MVV A;  3G29 A;  2QNW A;  3CPW O;  3CCS P;  2LL8 A;  2LML A;  1VQP P;  1F80 D;  2FVF A;  3GZL A;  4PH0 A;  2KOD A;  2KOR A;  1M6N A;  2VSQ A;  2KOS A;  1K9M Q;  2KG8 A;  2PEI A;  3CCU P;  2EHS A;  2LOL A;  1Q82 Q;  2CGQ A;  3DS4 A;  2ONT A;  4H2X C;  5BS2 A;  1A43 A;  5F2O A;  2LPK A;  2GZJ A;  3I55 P;  4COC A;  1VQO P;  1K8A Q;  1KQS O;  3CMA P;  2LTE A;  3GJN A;  1VHN A;  3HZQ A;  1BAJ A;  1IMP A;  2CG5 B;  2XXM A;  5HGN A;  4U0D A;  2WPT A;  2EFJ A;  2GZF A;  3CC2 P;  5HV8 A;  2GDX A;  1DNY A;  2KGC A;  2LF4 A;  4UHP B;  2X2B A;  1VQ9 P;  2L6E A;  1K30 A;  3G21 A;  1HQB A;  1Q7Y Q;  2L4B A;  3DTJ A;  3G1G A;  2GZG A;  1ACP A;  1QRJ A;  5HGL A;  4F37 A;  2ERH A;  2GZE A;  2FHS C;  4GR2 A;  1QVG O;  2KG6 A;  4QNB A;  1DV5 A;  3HYB A;  3GKL C;  5DCK A;  1YJN P;  3I56 P;  2KOO A;  2JYG A;  2GZI A;  2L0Q A;  4U0F A;  3CCL P;  1N8R Q;  4WYM A;  1FR2 A;  2M8L A;  2FVE A;  2AVA A;  2BHV A;  2JU1 A;  2K93 A;  4QKO A;  4BPH A;  2MY5 A;  2KOQ A;  2P9X A;  1VKU A;  2VLO A;  2MD9 A;  4COP A;  2FVA A;  1M1K Q;  1RO0 A;  3EJD A; 
#chains in the Genus database with same CATH homology
 3CCJ P;  3OW2 O;  3H0D A;  1M90 Q;  4PH0 A;  3DS0 A;  2KOD A;  1W2B O;  4IPY A;  1VQ6 P;  1M6N A;  1K9M Q;  3G71 P;  2M8N A;  1VQM P;  3DS5 A;  2PEI A;  3CCU P;  2Z46 A;  1Q82 Q;  3Q20 A;  3DS4 A;  1ZMB A;  2BUO A;  2ONT A;  5BS1 A;  5BS2 A;  1RO2 A;  1A43 A;  5F2O A;  2PEM A;  5JPA A;  3DPH A;  4COC A;  3I55 P;  1VQO P;  1K73 Q;  1VQK P;  3CCE P;  1K8A Q;  1YIJ P;  1KQS O;  2PEQ A;  3H4E A;  3CMA P;  2XV6 A;  1VQL P;  3HZQ A;  1BAJ A;  3E2D A;  1NJI Q;  3CD6 P;  1YHQ P;  2XXM A;  1D1D A;  4PH1 A;  5HGN A;  4U0D A;  5HGM A;  1M6E X;  2EFJ A;  4XFZ A;  1IUQ A;  3CCR P;  4GR6 A;  3CXC O;  3CC2 P;  4U0A A;  1JJ2 O;  1KC8 Q;  2LF4 A;  2Z44 A;  2OTJ P;  2QA4 P;  2Z45 A;  1VQ9 P;  3CCM P;  2L6E A;  1K30 A;  2PEK A;  5F2K A;  4U0E A;  4XRQ A;  3G21 A;  4XFY A;  3M1M A;  3VRL C;  3NTE A;  3H47 A;  5I4T G;  2PEN A;  1VQ4 P;  3G0V A;  1Q7Y Q;  3G28 A;  3CC4 P;  3DTJ A;  3G1G A;  3CCV P;  3G6E P;  1QRJ A;  3WBH A;  5HGL A;  2DGY A;  1YI2 P;  2OTL P;  1QVF O;  1A8O A;  4GR2 A;  1QVG O;  3G4S P;  3G26 A;  4QNB A;  1S72 P;  3DS2 A;  2EG5 A;  1E6J P;  2PEO A;  2OAR A;  3HYB A;  1RNI A;  2JO0 A;  3DS3 A;  5DCK A;  1YJN P;  3I56 P;  4M0I A;  2JYG A;  2XT1 A;  4U0F A;  2EIA A;  2M8P A;  1YJW P;  3CCL P;  1N8R Q;  1VQ5 P;  3CCQ P;  1KD1 Q;  5HGO A;  4WYM A;  4U0C A;  3B5I A;  1YJ9 P;  2PY8 A;  2M8L A;  1VQN P;  1EOQ A;  2BHV A;  2PEJ A;  1EIA A;  4XRO A;  3G1I A;  3MGE A;  5F2N A;  3CME P;  3DS1 A;  4U0B A;  1Q81 Q;  1M74 A;  3CC7 P;  2CWO A;  2P9X A;  1AUM A;  3G29 A;  1Q86 Q;  1YIT P;  3CPW O;  3RG6 C;  1VQ7 P;  4COP A;  3LRY A;  4XFX A;  1VQ8 P;  1M1K Q;  3P05 A;  2QEX P;  3CCS P;  2E1M A;  2JYL A;  1RO0 A;  1VQP P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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