2XV6A

Crystal structure of the hiv-1 capsid protein c-terminal domain (146- 220) in complex with a camelid vhh.
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
75
structure length
75
Chain Sequence
SPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPGATLEEMMTACQG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors
rcsb
molecule tags Viral protein/immune system
source organism Human immunodeficiency virus 1
molecule keywords CAPSID PROTEIN P24
total genus 28
structure length 75
sequence length 75
chains with identical sequence C
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2010-10-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.30 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A 2xv6A00
1E6JP 5I4TG 3DS1A 2L6EA 1EIAA 3DS2A 3DS0A 5HGNA 5DCKA 4COPA 4XFYA 3DS3A 3G21A 4U0DA 3DS5A 3NTEA 2M8NA 1BAJA 1A8OA 3DPHA 3MGEA 2JO0A 4U0BA 4PH1A 4XRQA 1AUMA 4COCA 4U0EA 4U0FA 4U0AA 2BUOA 3DS4A 3VRLC 2KODA 4WYMA 2EIAA 2LF4A 2XXMA 4PH0A 4XFZA 3G29A 3P05A 3H47A 1EOQA 3G1IA 4XFXA 5HGLA 2XV6A 2M8PA 2JYGA 5HGMA 3LRYA 4IPYA 2ONTA 5HGOA 1A43A 3DTJA 4U0CA 3G26A 3H4EA 3G0VA 4QNBA 2JYLA 5JPAA 1QRJA 1D1DA 3G28A 2XT1A 4M0IA 2M8LA 4XROA 3G1GA
chains in the Genus database with same CATH superfamily
2N50A 3GZMA 1A8OA 3OW2O 1AUMA 4U0FA 3CCLP 4U0AA 2MR7A 4PWVB 2KOPA 2JQ4A 5HVCA 1HY8A 1KD1Q 5HGOA 5EW5E 1Z6MA 2E1MA 2N6YA 2K0DX 2Z44A 5I4TG 1EMVA 5BS1A 4F37A 1BAJA 2VLOA 4U0BA 2FQ1A 2KORA 3I55P 2GDWA 1X3OA 1DV5A 1M90Q 3CPWO 2FQ2A 2FQ0A 4IZ6A 5DCKA 2BHVA 2K2QA 1GPJA 1GXGA 4QKOA 2AF8A 3H47A 4CA3A 1K9MQ 3CCSP 1L0IA 3B5IA 1VQKP 3G1GA 3CC4P 2OTJP 1EIAA 2VLNA 2GZJA 3CMEP 3DS3A 2CWOA 3CXCO 2LL8A 5HV8A 3MGEA 2MY5A 1YHQP 2M5RA 1YJNP 1NQ4A 1RO0A 1ACPA 1KLPA 4XFXA 1M6NA 2PEOA 4DG9A 2K0YA 3LRYA 1A43A 2LIWA 5JPAA 3G28A 3GKLC 5CZDB 2CNRA 4BPGA 1NJIQ 4U0EA 1VQ7P 1VQ6P 4NEOA 2XZ1C 1YI2P 2X2BA 2KGAA 1VQLP 4HKGA 2QA4P 3CCUP 1VQ8P 5KP6B 1MZ8A 2KOOA 1VQ4P 2VLQA 2DNWA 3G71P 1YJWP 1QVFO 2Z45A 4H2YC 2N6ZA 2GDXA 3G26A 3G6EP 4M0IA 1E6JP 2WPTA 1M74A 2JAZA 2FADA 2K0XA 4H2WC 3WBHA 3DS4A 2KGCA 2PNGA 2K93A 3CCEP 3G29A 3HYBA 2KGDA 1UJZA 2JU1A 2GDYA 4H2XC 4QNBA 3B4QA 1Q82Q 1D1DA 5F2NA 3G4SP 5EJDA 1Q81Q 1YITP 2KG6A 2EG5A 1IMPA 2K5XA 3RG2A 2GZGA 2AFDA 2N5IA 1DNYA 2FVEA 1AF8A 3GZLA 2GZIA 3E2DA 3Q20A 2GZEA 3CMAP 1FR2A 2KGEA 3DS1A 3DS0A 5BS2A 2ERHA 3G21A 4U0DA 2EHTA 3DPHA 1OR5A 2JO0A 2CQ8A 2FVAA 3VRLC 2LKIA 2EIAA 1Q7YQ 1M1KQ 2PEIA 2KOSA 2NO8A 1KC8Q 3DTJA 1ZMBA 3CCQP 1QRJA 5HGNA 2LPKA 2CGQA 4XRQA 3CCJP 7CEIA 2AVAA 2XXMA 1IMQA 1VQPP 5KP8B 3G1IA 2N98A 2M8PA 5HGMA 3H4EA 2JYLA 1K73Q 2DGYA 2PEJA 2M8LA 3CCRP 3CD6P 2LOLA 2P9XA 4PXHB 1AYIA 2MVUA 2ROQA 2LIUA 2EHSA 2KWLA 1QVGO 3LMOA 2L22A 2JB0A 3CE7A 3I56P 2FHSC 2AFEA 2L9FA 1UNKA 2FVFA 4U0CA 3CC2P 2FACA 2XZ0D 3H0DA 4UHPB 2L6EA 3EJBA 2MVVA 3DS2A 3EJEA 4R0MA 3NTEA 1F80D 2CG5B 2N5HA 2JGPA 2PEQA 4PH1A 2VSQA 2GZFA 3EJDA 1VQOP 3U43A 1N8RQ 1VQ9P 4XFZA 1M6EX 1YIJP 1VQ5P 1YJ9P 4BPHA 3RG6C 1VHNA 2PENA 2OARA 1K8AQ 1GXHA 1RO2A 3CC7P 5F2OA 4BPFA 3CCVP 3GJNA 5KP7B 2VLPA 4GR2A 5F2KA 2LF4A 1L0HA 2L4BA 2K92A 1K30A 2ONTA 2JBGA 4MRTC 1BXIA 4COPA 3HZQA 2KG9A 2M8NA 2QNWA 2LMLA 1JJ2O 2L0QA 4COCA 4GR6A 2PY8A 2EFJA 1EOQA 2MD9A 1CEIA 2QEXP 1ZNVA 2OTLP 2KW2A 3M1MA 1KQSO 1Q86Q 2XT1A 1S72P 3CCMP 4XFYA 3DS5A 1VQMP 1W2BO 1E0HA 2PEMA 2KODA 2FAEA 4PH0A 2MF4A 3P05A 5HGLA 1HQBA 1VKUA 1T8KA 4IPYA 2KOQA 1VQNP 2KR5A 1IUQA 3G0VA 2JU2A 4XROA 2KG8A 2LTEA 2K94A 2GYKA 2MR8A 2BUOA 2Z46A 3NY7B 4WYMA 2PEKA 2XV6A 2JYGA 1RNIA
chains in the Genus database with same CATH topology
3DS1A 3DS0A 5BS2A 3G21A 4U0DA 1RO2A 3CC7P 5F2OA 3DPHA 1A8OA 3CCVP 3OW2O 2JO0A 1NJIQ 1AUMA 4U0EA 4U0FA 4U0AA 3CCLP 3VRLC 4GR2A 1VQ7P 5F2KA 1VQ6P 2EIAA 2LF4A 1Q7YQ 1M1KQ 1YI2P 2PEIA 1KD1Q 1K30A 5HGOA 1KC8Q 2ONTA 3DTJA 1VQLP 1ZMBA 3CCQP 1QRJA 2E1MA 2Z44A 2QA4P 3CCUP 5I4TG 1VQ8P 5HGNA 4COPA 5BS1A 3HZQA 1VQ4P 2M8NA 1BAJA 1JJ2O 4U0BA 4XRQA 4COCA 3G71P 3CCJP 4GR6A 3I55P 1YJWP 2PY8A 1QVFO 2XXMA 2Z45A 2EFJA 1VQPP 1EOQA 3G1IA 2M8PA 2QEXP 1M90Q 5HGMA 2OTLP 3G26A 3H4EA 3M1MA 3CPWO 3G6EP 2JYLA 1KQSO 1Q86Q 1K73Q 2DGYA 2PEJA 2XT1A 4M0IA 2M8LA 3CCRP 3CD6P 1E6JP 1S72P 2P9XA 5DCKA 3CCMP 4XFYA 3DS5A 2BHVA 1VQMP 1W2BO 1M74A 1QVGO 3WBHA 2PEMA 3DS4A 2KODA 4PH0A 3I56P 3CCEP 3G29A 3HYBA 3H47A 3P05A 5HGLA 1K9MQ 3B5IA 4IPYA 3CCSP 1VQNP 4U0CA 1IUQA 4QNBA 3G0VA 1VQKP 3CC2P 1Q82Q 1D1DA 5F2NA 3H0DA 4XROA 3G4SP 1Q81Q 3G1GA 1YITP 3CC4P 2OTJP 2L6EA 1EIAA 3DS2A 3CMEP 3DS3A 2CWOA 3NTEA 3CXCO 2EG5A 3MGEA 2PEQA 4PH1A 1YHQP 2BUOA 2Z46A 4WYMA 1YJNP 1VQOP 1RO0A 1N8RQ 1VQ9P 4XFZA 1M6EX 1YIJP 2PEKA 4XFXA 1M6NA 1VQ5P 2PEOA 2XV6A 1YJ9P 3RG6C 2JYGA 3LRYA 2PENA 1A43A 2OARA 1RNIA 3E2DA 5JPAA 3G28A 3Q20A 3CMAP 1K8AQ
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E6J P;  5I4T G;  3DS1 A;  2L6E A;  1EIA A;  3DS2 A;  3DS0 A;  5HGN A;  5DCK A;  4COP A;  4XFY A;  3DS3 A;  3G21 A;  4U0D A;  3DS5 A;  3NTE A;  2M8N A;  1BAJ A;  1A8O A;  3DPH A;  3MGE A;  2JO0 A;  4U0B A;  4PH1 A;  4XRQ A;  1AUM A;  4COC A;  4U0E A;  4U0F A;  4U0A A;  2BUO A;  3DS4 A;  3VRL C;  2KOD A;  4WYM A;  2EIA A;  2LF4 A;  2XXM A;  4PH0 A;  4XFZ A;  3G29 A;  3P05 A;  3H47 A;  1EOQ A;  3G1I A;  4XFX A;  5HGL A;  2XV6 A;  2M8P A;  2JYG A;  5HGM A;  3LRY A;  4IPY A;  2ONT A;  5HGO A;  1A43 A;  3DTJ A;  4U0C A;  3G26 A;  3H4E A;  3G0V A;  4QNB A;  2JYL A;  5JPA A;  1QRJ A;  1D1D A;  3G28 A;  2XT1 A;  4M0I A;  2M8L A;  4XRO A;  3G1G A; 
#chains in the Genus database with same CATH topology
 2N50 A;  3GZM A;  1A8O A;  3OW2 O;  1AUM A;  4U0F A;  3CCL P;  4U0A A;  2MR7 A;  4PWV B;  2KOP A;  2JQ4 A;  5HVC A;  1HY8 A;  1KD1 Q;  5HGO A;  5EW5 E;  1Z6M A;  2E1M A;  2N6Y A;  2K0D X;  2Z44 A;  5I4T G;  1EMV A;  5BS1 A;  4F37 A;  1BAJ A;  2VLO A;  4U0B A;  2FQ1 A;  2KOR A;  3I55 P;  2GDW A;  1X3O A;  1DV5 A;  1M90 Q;  3CPW O;  2FQ2 A;  2FQ0 A;  4IZ6 A;  5DCK A;  2BHV A;  2K2Q A;  1GPJ A;  1GXG A;  4QKO A;  2AF8 A;  3H47 A;  4CA3 A;  1K9M Q;  3CCS P;  1L0I A;  3B5I A;  1VQK P;  3G1G A;  3CC4 P;  2OTJ P;  1EIA A;  2VLN A;  2GZJ A;  3CME P;  3DS3 A;  2CWO A;  3CXC O;  2LL8 A;  5HV8 A;  3MGE A;  2MY5 A;  1YHQ P;  2M5R A;  1YJN P;  1NQ4 A;  1RO0 A;  1ACP A;  1KLP A;  4XFX A;  1M6N A;  2PEO A;  4DG9 A;  2K0Y A;  3LRY A;  1A43 A;  2LIW A;  5JPA A;  3G28 A;  3GKL C;  5CZD B;  2CNR A;  4BPG A;  1NJI Q;  4U0E A;  1VQ7 P;  1VQ6 P;  4NEO A;  2XZ1 C;  1YI2 P;  2X2B A;  2KGA A;  1VQL P;  4HKG A;  2QA4 P;  3CCU P;  1VQ8 P;  5KP6 B;  1MZ8 A;  2KOO A;  1VQ4 P;  2VLQ A;  2DNW A;  3G71 P;  1YJW P;  1QVF O;  2Z45 A;  4H2Y C;  2N6Z A;  2GDX A;  3G26 A;  3G6E P;  4M0I A;  1E6J P;  2WPT A;  1M74 A;  2JAZ A;  2FAD A;  2K0X A;  4H2W C;  3WBH A;  3DS4 A;  2KGC A;  2PNG A;  2K93 A;  3CCE P;  3G29 A;  3HYB A;  2KGD A;  1UJZ A;  2JU1 A;  2GDY A;  4H2X C;  4QNB A;  3B4Q A;  1Q82 Q;  1D1D A;  5F2N A;  3G4S P;  5EJD A;  1Q81 Q;  1YIT P;  2KG6 A;  2EG5 A;  1IMP A;  2K5X A;  3RG2 A;  2GZG A;  2AFD A;  2N5I A;  1DNY A;  2FVE A;  1AF8 A;  3GZL A;  2GZI A;  3E2D A;  3Q20 A;  2GZE A;  3CMA P;  1FR2 A;  2KGE A;  3DS1 A;  3DS0 A;  5BS2 A;  2ERH A;  3G21 A;  4U0D A;  2EHT A;  3DPH A;  1OR5 A;  2JO0 A;  2CQ8 A;  2FVA A;  3VRL C;  2LKI A;  2EIA A;  1Q7Y Q;  1M1K Q;  2PEI A;  2KOS A;  2NO8 A;  1KC8 Q;  3DTJ A;  1ZMB A;  3CCQ P;  1QRJ A;  5HGN A;  2LPK A;  2CGQ A;  4XRQ A;  3CCJ P;  7CEI A;  2AVA A;  2XXM A;  1IMQ A;  1VQP P;  5KP8 B;  3G1I A;  2N98 A;  2M8P A;  5HGM A;  3H4E A;  2JYL A;  1K73 Q;  2DGY A;  2PEJ A;  2M8L A;  3CCR P;  3CD6 P;  2LOL A;  2P9X A;  4PXH B;  1AYI A;  2MVU A;  2ROQ A;  2LIU A;  2EHS A;  2KWL A;  1QVG O;  3LMO A;  2L22 A;  2JB0 A;  3CE7 A;  3I56 P;  2FHS C;  2AFE A;  2L9F A;  1UNK A;  2FVF A;  4U0C A;  3CC2 P;  2FAC A;  2XZ0 D;  3H0D A;  4UHP B;  2L6E A;  3EJB A;  2MVV A;  3DS2 A;  3EJE A;  4R0M A;  3NTE A;  1F80 D;  2CG5 B;  2N5H A;  2JGP A;  2PEQ A;  4PH1 A;  2VSQ A;  2GZF A;  3EJD A;  1VQO P;  3U43 A;  1N8R Q;  1VQ9 P;  4XFZ A;  1M6E X;  1YIJ P;  1VQ5 P;  1YJ9 P;  4BPH A;  3RG6 C;  1VHN A;  2PEN A;  2OAR A;  1K8A Q;  1GXH A;  1RO2 A;  3CC7 P;  5F2O A;  4BPF A;  3CCV P;  3GJN A;  5KP7 B;  2VLP A;  4GR2 A;  5F2K A;  2LF4 A;  1L0H A;  2L4B A;  2K92 A;  1K30 A;  2ONT A;  2JBG A;  4MRT C;  1BXI A;  4COP A;  3HZQ A;  2KG9 A;  2M8N A;  2QNW A;  2LML A;  1JJ2 O;  2L0Q A;  4COC A;  4GR6 A;  2PY8 A;  2EFJ A;  1EOQ A;  2MD9 A;  1CEI A;  2QEX P;  1ZNV A;  2OTL P;  2KW2 A;  3M1M A;  1KQS O;  1Q86 Q;  2XT1 A;  1S72 P;  3CCM P;  4XFY A;  3DS5 A;  1VQM P;  1W2B O;  1E0H A;  2PEM A;  2KOD A;  2FAE A;  4PH0 A;  2MF4 A;  3P05 A;  5HGL A;  1HQB A;  1VKU A;  1T8K A;  4IPY A;  2KOQ A;  1VQN P;  2KR5 A;  1IUQ A;  3G0V A;  2JU2 A;  4XRO A;  2KG8 A;  2LTE A;  2K94 A;  2GYK A;  2MR8 A;  2BUO A;  2Z46 A;  3NY7 B;  4WYM A;  2PEK A;  2XV6 A;  2JYG A;  1RNI A; 
#chains in the Genus database with same CATH homology
 3DS1 A;  3DS0 A;  5BS2 A;  3G21 A;  4U0D A;  1RO2 A;  3CC7 P;  5F2O A;  3DPH A;  1A8O A;  3CCV P;  3OW2 O;  2JO0 A;  1NJI Q;  1AUM A;  4U0E A;  4U0F A;  4U0A A;  3CCL P;  3VRL C;  4GR2 A;  1VQ7 P;  5F2K A;  1VQ6 P;  2EIA A;  2LF4 A;  1Q7Y Q;  1M1K Q;  1YI2 P;  2PEI A;  1KD1 Q;  1K30 A;  5HGO A;  1KC8 Q;  2ONT A;  3DTJ A;  1VQL P;  1ZMB A;  3CCQ P;  1QRJ A;  2E1M A;  2Z44 A;  2QA4 P;  3CCU P;  5I4T G;  1VQ8 P;  5HGN A;  4COP A;  5BS1 A;  3HZQ A;  1VQ4 P;  2M8N A;  1BAJ A;  1JJ2 O;  4U0B A;  4XRQ A;  4COC A;  3G71 P;  3CCJ P;  4GR6 A;  3I55 P;  1YJW P;  2PY8 A;  1QVF O;  2XXM A;  2Z45 A;  2EFJ A;  1VQP P;  1EOQ A;  3G1I A;  2M8P A;  2QEX P;  1M90 Q;  5HGM A;  2OTL P;  3G26 A;  3H4E A;  3M1M A;  3CPW O;  3G6E P;  2JYL A;  1KQS O;  1Q86 Q;  1K73 Q;  2DGY A;  2PEJ A;  2XT1 A;  4M0I A;  2M8L A;  3CCR P;  3CD6 P;  1E6J P;  1S72 P;  2P9X A;  5DCK A;  3CCM P;  4XFY A;  3DS5 A;  2BHV A;  1VQM P;  1W2B O;  1M74 A;  1QVG O;  3WBH A;  2PEM A;  3DS4 A;  2KOD A;  4PH0 A;  3I56 P;  3CCE P;  3G29 A;  3HYB A;  3H47 A;  3P05 A;  5HGL A;  1K9M Q;  3B5I A;  4IPY A;  3CCS P;  1VQN P;  4U0C A;  1IUQ A;  4QNB A;  3G0V A;  1VQK P;  3CC2 P;  1Q82 Q;  1D1D A;  5F2N A;  3H0D A;  4XRO A;  3G4S P;  1Q81 Q;  3G1G A;  1YIT P;  3CC4 P;  2OTJ P;  2L6E A;  1EIA A;  3DS2 A;  3CME P;  3DS3 A;  2CWO A;  3NTE A;  3CXC O;  2EG5 A;  3MGE A;  2PEQ A;  4PH1 A;  1YHQ P;  2BUO A;  2Z46 A;  4WYM A;  1YJN P;  1VQO P;  1RO0 A;  1N8R Q;  1VQ9 P;  4XFZ A;  1M6E X;  1YIJ P;  2PEK A;  4XFX A;  1M6N A;  1VQ5 P;  2PEO A;  2XV6 A;  1YJ9 P;  3RG6 C;  2JYG A;  3LRY A;  2PEN A;  1A43 A;  2OAR A;  1RNI A;  3E2D A;  5JPA A;  3G28 A;  3Q20 A;  3CMA P;  1K8A Q; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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