2XXM | Genus

Total Genus 25

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	25
sequence length	73
structure length	73
Chain Sequence	SPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPGATLEEMMTAC

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Immune system/peptide
source organism	Human immunodeficiency virus
publication title	Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors rcsb
molecule keywords	CAPSID PROTEIN P24
total genus	25
structure length	73
sequence length	73
ec nomenclature	ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date	2010-11-10

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.1200.30	Mainly Alpha	Orthogonal Bundle	Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A	Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A	2xxmA00

2XT1A 3DS4A 3G0VA 4XFYA 2KODA 3DS2A 2JYGA 2ONTA 1BAJA 2JYLA 2L6EA 3G28A 4U0DA 2M8NA 4WYMA 4XROA 4PH0A 3G1IA 3P05A 3DS0A 4U0EA 3G21A 4IPYA 5DCKA 4COCA 3H47A 1QRJA 1D1DA 4XFXA 2JO0A 1E6JP 3NTEA 3DS5A 4XRQA 4U0BA 5I4TG 3DS1A 2M8PA 2XXMA 3H4EA 3G26A 4U0AA 2M8LA 5HGNA 4U0FA 1A8OA 3MGEA 3DPHA 4M0IA 5HGMA 5HGLA 2EIAA 4QNBA 4XFZA 4PH1A 3VRLC 4COPA 1EIAA 1EOQA 2XV6A 3DS3A 1A43A 3DTJA 3G29A 4U0CA 2BUOA 1AUMA 3G1GA 5HGOA 3LRYA 5JPAA 2LF4A
chains in the Genus database with same CATH superfamily

3CMAP 1M74A 1KQSO 3RG6C 1QVFO 1X3OA 2K0DX 1VHNA 2N5IA 2FQ0A 4R0MA 4CA3A 3OW2O 4U0FA 1VQNP 1VQPP 2QA4P 2PEIA 1KD1Q 2JBGA 2FVEA 4COPA 1AUMA 3HZQA 2XT1A 1L0HA 2GDYA 5HV8A 3CCSP 5KP8B 1YJNP 2JQ4A 5DCKA 4IZ6A 2JO0A 3CCJP 2FHSC 1FR2A 2XXMA 1ZNVA 3H4EA 3MGEA 1CEIA 1IMPA 4NEOA 2LKIA 2PEKA 2CGQA 4H2XC 3CCVP 1T8KA 2ONTA 3G4SP 2PNGA 3GKLC 1F80D 2L9FA 2LIUA 2K0YA 4BPHA 3I55P 4U0AA 2LMLA 1GXGA 5EW5E 1KC8Q 3E2DA 2EHTA 1IUQA 2VLOA 4U0DA 2M8NA 3CE7A 1M90Q 1JJ2O 2KGDA 2KG8A 2PEOA 1D1DA 2JGPA 1VQ7P 2OTLP 3NTEA 2AVAA 4U0BA 1VQLP 1M6EX 1DNYA 3DPHA 1EIAA 1L0IA 2BHVA 1AF8A 1MZ8A 2L6EA 3GZMA 3DS0A 3CMEP 2FACA 3HYBA 2M5RA 1E6JP 2WPTA 1VKUA 1NQ4A 2MR8A 2GDWA 3EJDA 2XZ1C 2N98A 1VQMP 3G71P 3DTJA 2MR7A 1YITP 4XROA 2QNWA 1Q7YQ 3WBHA 3H47A 2MY5A 1N8RQ 2CNRA 1UJZA 2GZEA 2X2BA 5BS1A 2OTJP 3CCUP 3CCEP 4PH1A 1A43A 1YJWP 1EMVA 2LF4A 4XFYA 2KODA 3GJNA 2L4BA 2JYGA 2JU2A 1VQ5P 2VLQA 1S72P 2KR5A 3B5IA 1K30A 3Q20A 1VQOP 2K2QA 2P9XA 3RG2A 1M6NA 1NJIQ 3DS3A 5HGOA 2QEXP 1YI2P 1HY8A 4H2WC 2JYLA 2N5HA 3P05A 5EJDA 3CCQP 1QRJA 4XFXA 2ERHA 1ZMBA 5HGNA 2MF4A 3B4QA 2FQ2A 3CC4P 2EIAA 2K5XA 2XV6A 2GZFA 2KOOA 5JPAA 2JB0A 2DGYA 1OR5A 3LMOA 2GZIA 1Q81Q 3CC2P 3G28A 2KOPA 4COCA 5HVCA 1VQ4P 5KP6B 3DS5A 3H0DA 4M0IA 1YIJP 2N6ZA 2Z45A 3CC7P 3VRLC 1EOQA 2KORA 4WYMA 3I56P 3G21A 1K73Q 1E0HA 2PENA 4XRQA 2L0QA 2AF8A 2JAZA 2MVUA 2XZ0D 2MVVA 2ROQA 3CPWO 4QNBA 2LL8A 4GR6A 1DV5A 4GR2A 1K8AQ 2VLPA 1Q82Q 2GZJA 1IMQA 1VQKP 2MD9A 3DS1A 4UHPB 2PEQA 3LRYA 3CD6P 2GZGA 2KG6A 1M1KQ 1VQ6P 3G6EP 1BXIA 3G1IA 4U0EA 4F37A 1UNKA 4BPGA 2OARA 3EJEA 2E1MA 7CEIA 1A8OA 2GDXA 5HGMA 2AFDA 4XFZA 2K93A 1YHQP 3CCLP 2DNWA 2LOLA 2KWLA 2Z46A 2N50A 3M1MA 2KOSA 1VQ8P 4PWVB 5F2NA 2VLNA 2K94A 2M8PA 2KGCA 1W2BO 2LTEA 3CCRP 2FVFA 1RNIA 1K9MQ 1RO2A 2LPKA 3CCMP 2N6YA 2BUOA 2KGEA 3G1GA 1GPJA 3CXCO 1HQBA 2PEMA 2K92A 2KG9A 4PH0A 4MRTC 2FADA 1RO0A 1VQ9P 2PY8A 3EJBA 3GZLA 2KOQA 2M8LA 3G26A 5KP7B 2NO8A 1ACPA 5CZDB 2CG5B 3G29A 2GYKA 2EG5A 5F2OA 3U43A 4HKGA 5BS2A 4BPFA 2PEJA 2EFJA 2FVAA 1AYIA 1Q86Q 4QKOA 1YJ9P 2L22A 3NY7B 2VSQA 2AFEA 2K0XA 2FAEA 1KLPA 5F2KA 4U0CA 3DS4A 3G0VA 4PXHB 3DS2A 1BAJA 2CQ8A 4H2YC 2Z44A 4IPYA 2KW2A 2CWOA 4DG9A 1GXHA 2EHSA 2LIWA 5I4TG 1Z6MA 2KGAA 1QVGO 2FQ1A 5HGLA 2JU1A
chains in the Genus database with same CATH topology

3CMAP 1Q81Q 3CC2P 1M74A 2Z46A 1KQSO 2L6EA 3G28A 3RG6C 1QVFO 3M1MA 3DS0A 3CMEP 4COCA 1VQ8P 1VQ4P 3HYBA 1E6JP 3DS5A 5F2NA 2M8PA 3OW2O 1W2BO 3H0DA 4U0FA 3CCRP 1VQNP 4M0IA 1VQPP 2QA4P 1RNIA 1YIJP 2PEIA 1K9MQ 2Z45A 3CC7P 1RO2A 1VQMP 1KD1Q 3VRLC 3G71P 4COPA 1EOQA 3DTJA 3CCMP 2BUOA 1AUMA 3G1GA 1YITP 3HZQA 2XT1A 3CXCO 2PEMA 4XROA 4PH0A 3CCSP 4WYMA 1YJNP 1Q7YQ 3I56P 5DCKA 3G21A 1RO0A 3WBHA 3H47A 1K73Q 1VQ9P 1N8RQ 2PY8A 5BS1A 2JO0A 2PENA 4XRQA 3CCJP 2XXMA 3H4EA 3G26A 2M8LA 2OTJP 3MGEA 3CCUP 3CPWO 4QNBA 3CCEP 4PH1A 1A43A 3G29A 2EG5A 5F2OA 4GR6A 1YJWP 2LF4A 2PEKA 4GR2A 1K8AQ 4XFYA 3CCVP 2KODA 2JYGA 2ONTA 1Q82Q 3G4SP 5BS2A 1VQ5P 2PEJA 2EFJA 1S72P 1Q86Q 1VQKP 3B5IA 1YJ9P 1K30A 3Q20A 3DS1A 1VQOP 3I55P 4U0AA 2P9XA 1M6NA 2PEQA 1KC8Q 1NJIQ 3E2DA 5F2KA 3DS3A 4U0CA 5HGOA 2QEXP 3LRYA 1YI2P 3CD6P 3DS4A 3G0VA 1IUQA 3DS2A 1M1KQ 1VQ6P 1BAJA 2JYLA 4U0DA 3G6EP 2M8NA 2Z44A 3G1IA 3P05A 4U0EA 4IPYA 2CWOA 1M90Q 1JJ2O 3CCQP 1QRJA 2PEOA 1D1DA 4XFXA 2OARA 1VQ7P 3NTEA 2OTLP 4U0BA 5I4TG 2E1MA 1ZMBA 5HGNA 1VQLP 1M6EX 1A8OA 3DPHA 5HGMA 1QVGO 3CC4P 5HGLA 2EIAA 4XFZA 1YHQP 1EIAA 2XV6A 3CCLP 5JPAA 2DGYA 2BHVA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2XT1 A;  3DS4 A;  3G0V A;  4XFY A;  2KOD A;  3DS2 A;  2JYG A;  2ONT A;  1BAJ A;  2JYL A;  2L6E A;  3G28 A;  4U0D A;  2M8N A;  4WYM A;  4XRO A;  4PH0 A;  3G1I A;  3P05 A;  3DS0 A;  4U0E A;  3G21 A;  4IPY A;  5DCK A;  4COC A;  3H47 A;  1QRJ A;  1D1D A;  4XFX A;  2JO0 A;  1E6J P;  3NTE A;  3DS5 A;  4XRQ A;  4U0B A;  5I4T G;  3DS1 A;  2M8P A;  2XXM A;  3H4E A;  3G26 A;  4U0A A;  2M8L A;  5HGN A;  4U0F A;  1A8O A;  3MGE A;  3DPH A;  4M0I A;  5HGM A;  5HGL A;  2EIA A;  4QNB A;  4XFZ A;  4PH1 A;  3VRL C;  4COP A;  1EIA A;  1EOQ A;  2XV6 A;  3DS3 A;  1A43 A;  3DTJ A;  3G29 A;  4U0C A;  2BUO A;  1AUM A;  3G1G A;  5HGO A;  3LRY A;  5JPA A;  2LF4 A; 
#chains in the Genus database with same CATH topology
 3CMA P;  1M74 A;  1KQS O;  3RG6 C;  1QVF O;  1X3O A;  2K0D X;  1VHN A;  2N5I A;  2FQ0 A;  4R0M A;  4CA3 A;  3OW2 O;  4U0F A;  1VQN P;  1VQP P;  2QA4 P;  2PEI A;  1KD1 Q;  2JBG A;  2FVE A;  4COP A;  1AUM A;  3HZQ A;  2XT1 A;  1L0H A;  2GDY A;  5HV8 A;  3CCS P;  5KP8 B;  1YJN P;  2JQ4 A;  5DCK A;  4IZ6 A;  2JO0 A;  3CCJ P;  2FHS C;  1FR2 A;  2XXM A;  1ZNV A;  3H4E A;  3MGE A;  1CEI A;  1IMP A;  4NEO A;  2LKI A;  2PEK A;  2CGQ A;  4H2X C;  3CCV P;  1T8K A;  2ONT A;  3G4S P;  2PNG A;  3GKL C;  1F80 D;  2L9F A;  2LIU A;  2K0Y A;  4BPH A;  3I55 P;  4U0A A;  2LML A;  1GXG A;  5EW5 E;  1KC8 Q;  3E2D A;  2EHT A;  1IUQ A;  2VLO A;  4U0D A;  2M8N A;  3CE7 A;  1M90 Q;  1JJ2 O;  2KGD A;  2KG8 A;  2PEO A;  1D1D A;  2JGP A;  1VQ7 P;  2OTL P;  3NTE A;  2AVA A;  4U0B A;  1VQL P;  1M6E X;  1DNY A;  3DPH A;  1EIA A;  1L0I A;  2BHV A;  1AF8 A;  1MZ8 A;  2L6E A;  3GZM A;  3DS0 A;  3CME P;  2FAC A;  3HYB A;  2M5R A;  1E6J P;  2WPT A;  1VKU A;  1NQ4 A;  2MR8 A;  2GDW A;  3EJD A;  2XZ1 C;  2N98 A;  1VQM P;  3G71 P;  3DTJ A;  2MR7 A;  1YIT P;  4XRO A;  2QNW A;  1Q7Y Q;  3WBH A;  3H47 A;  2MY5 A;  1N8R Q;  2CNR A;  1UJZ A;  2GZE A;  2X2B A;  5BS1 A;  2OTJ P;  3CCU P;  3CCE P;  4PH1 A;  1A43 A;  1YJW P;  1EMV A;  2LF4 A;  4XFY A;  2KOD A;  3GJN A;  2L4B A;  2JYG A;  2JU2 A;  1VQ5 P;  2VLQ A;  1S72 P;  2KR5 A;  3B5I A;  1K30 A;  3Q20 A;  1VQO P;  2K2Q A;  2P9X A;  3RG2 A;  1M6N A;  1NJI Q;  3DS3 A;  5HGO A;  2QEX P;  1YI2 P;  1HY8 A;  4H2W C;  2JYL A;  2N5H A;  3P05 A;  5EJD A;  3CCQ P;  1QRJ A;  4XFX A;  2ERH A;  1ZMB A;  5HGN A;  2MF4 A;  3B4Q A;  2FQ2 A;  3CC4 P;  2EIA A;  2K5X A;  2XV6 A;  2GZF A;  2KOO A;  5JPA A;  2JB0 A;  2DGY A;  1OR5 A;  3LMO A;  2GZI A;  1Q81 Q;  3CC2 P;  3G28 A;  2KOP A;  4COC A;  5HVC A;  1VQ4 P;  5KP6 B;  3DS5 A;  3H0D A;  4M0I A;  1YIJ P;  2N6Z A;  2Z45 A;  3CC7 P;  3VRL C;  1EOQ A;  2KOR A;  4WYM A;  3I56 P;  3G21 A;  1K73 Q;  1E0H A;  2PEN A;  4XRQ A;  2L0Q A;  2AF8 A;  2JAZ A;  2MVU A;  2XZ0 D;  2MVV A;  2ROQ A;  3CPW O;  4QNB A;  2LL8 A;  4GR6 A;  1DV5 A;  4GR2 A;  1K8A Q;  2VLP A;  1Q82 Q;  2GZJ A;  1IMQ A;  1VQK P;  2MD9 A;  3DS1 A;  4UHP B;  2PEQ A;  3LRY A;  3CD6 P;  2GZG A;  2KG6 A;  1M1K Q;  1VQ6 P;  3G6E P;  1BXI A;  3G1I A;  4U0E A;  4F37 A;  1UNK A;  4BPG A;  2OAR A;  3EJE A;  2E1M A;  7CEI A;  1A8O A;  2GDX A;  5HGM A;  2AFD A;  4XFZ A;  2K93 A;  1YHQ P;  3CCL P;  2DNW A;  2LOL A;  2KWL A;  2Z46 A;  2N50 A;  3M1M A;  2KOS A;  1VQ8 P;  4PWV B;  5F2N A;  2VLN A;  2K94 A;  2M8P A;  2KGC A;  1W2B O;  2LTE A;  3CCR P;  2FVF A;  1RNI A;  1K9M Q;  1RO2 A;  2LPK A;  3CCM P;  2N6Y A;  2BUO A;  2KGE A;  3G1G A;  1GPJ A;  3CXC O;  1HQB A;  2PEM A;  2K92 A;  2KG9 A;  4PH0 A;  4MRT C;  2FAD A;  1RO0 A;  1VQ9 P;  2PY8 A;  3EJB A;  3GZL A;  2KOQ A;  2M8L A;  3G26 A;  5KP7 B;  2NO8 A;  1ACP A;  5CZD B;  2CG5 B;  3G29 A;  2GYK A;  2EG5 A;  5F2O A;  3U43 A;  4HKG A;  5BS2 A;  4BPF A;  2PEJ A;  2EFJ A;  2FVA A;  1AYI A;  1Q86 Q;  4QKO A;  1YJ9 P;  2L22 A;  3NY7 B;  2VSQ A;  2AFE A;  2K0X A;  2FAE A;  1KLP A;  5F2K A;  4U0C A;  3DS4 A;  3G0V A;  4PXH B;  3DS2 A;  1BAJ A;  2CQ8 A;  4H2Y C;  2Z44 A;  4IPY A;  2KW2 A;  2CWO A;  4DG9 A;  1GXH A;  2EHS A;  2LIW A;  5I4T G;  1Z6M A;  2KGA A;  1QVG O;  2FQ1 A;  5HGL A;  2JU1 A; 
#chains in the Genus database with same CATH homology
 3CMA P;  1Q81 Q;  3CC2 P;  1M74 A;  2Z46 A;  1KQS O;  2L6E A;  3G28 A;  3RG6 C;  1QVF O;  3M1M A;  3DS0 A;  3CME P;  4COC A;  1VQ8 P;  1VQ4 P;  3HYB A;  1E6J P;  3DS5 A;  5F2N A;  2M8P A;  3OW2 O;  1W2B O;  3H0D A;  4U0F A;  3CCR P;  1VQN P;  4M0I A;  1VQP P;  2QA4 P;  1RNI A;  1YIJ P;  2PEI A;  1K9M Q;  2Z45 A;  3CC7 P;  1RO2 A;  1VQM P;  1KD1 Q;  3VRL C;  3G71 P;  4COP A;  1EOQ A;  3DTJ A;  3CCM P;  2BUO A;  1AUM A;  3G1G A;  1YIT P;  3HZQ A;  2XT1 A;  3CXC O;  2PEM A;  4XRO A;  4PH0 A;  3CCS P;  4WYM A;  1YJN P;  1Q7Y Q;  3I56 P;  5DCK A;  3G21 A;  1RO0 A;  3WBH A;  3H47 A;  1K73 Q;  1VQ9 P;  1N8R Q;  2PY8 A;  5BS1 A;  2JO0 A;  2PEN A;  4XRQ A;  3CCJ P;  2XXM A;  3H4E A;  3G26 A;  2M8L A;  2OTJ P;  3MGE A;  3CCU P;  3CPW O;  4QNB A;  3CCE P;  4PH1 A;  1A43 A;  3G29 A;  2EG5 A;  5F2O A;  4GR6 A;  1YJW P;  2LF4 A;  2PEK A;  4GR2 A;  1K8A Q;  4XFY A;  3CCV P;  2KOD A;  2JYG A;  2ONT A;  1Q82 Q;  3G4S P;  5BS2 A;  1VQ5 P;  2PEJ A;  2EFJ A;  1S72 P;  1Q86 Q;  1VQK P;  3B5I A;  1YJ9 P;  1K30 A;  3Q20 A;  3DS1 A;  1VQO P;  3I55 P;  4U0A A;  2P9X A;  1M6N A;  2PEQ A;  1KC8 Q;  1NJI Q;  3E2D A;  5F2K A;  3DS3 A;  4U0C A;  5HGO A;  2QEX P;  3LRY A;  1YI2 P;  3CD6 P;  3DS4 A;  3G0V A;  1IUQ A;  3DS2 A;  1M1K Q;  1VQ6 P;  1BAJ A;  2JYL A;  4U0D A;  3G6E P;  2M8N A;  2Z44 A;  3G1I A;  3P05 A;  4U0E A;  4IPY A;  2CWO A;  1M90 Q;  1JJ2 O;  3CCQ P;  1QRJ A;  2PEO A;  1D1D A;  4XFX A;  2OAR A;  1VQ7 P;  3NTE A;  2OTL P;  4U0B A;  5I4T G;  2E1M A;  1ZMB A;  5HGN A;  1VQL P;  1M6E X;  1A8O A;  3DPH A;  5HGM A;  1QVG O;  3CC4 P;  5HGL A;  2EIA A;  4XFZ A;  1YHQ P;  1EIA A;  2XV6 A;  3CCL P;  5JPA A;  2DGY A;  2BHV A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2XXMA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

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