2CG5B

Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme a
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
71
structure length
71
Chain Sequence
QRDLVEAVAHILGIRDLAAVNLDSSLADLGLDALMSVEVRQTLERELNLVLSVREVRQLTLRKLQELSSKA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mechanism and Substrate Recognition of Human Holo Acp Synthase.
pubmed doi rcsb
molecule tags Transferase/hydrolase
source organism Homo sapiens
molecule keywords L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINY
total genus 19
structure length 71
sequence length 71
ec nomenclature ec 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase.
pdb deposition date 2006-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 2cg5B00
2N5HA 2KGEA 2KOQA 5HV8A 1F80D 4IZ6A 2LL8A 2N6YA 4PWVB 2K93A 2CG5B 4BPGA 2L0QA 2MR7A 2ROQA 2JQ4A 3EJBA 2CQ8A 2N98A 2FVAA 2FQ0A 2GDYA 2LTEA 5HVCA 2KG9A 3GZLA 2KOPA 1T8KA 3GZMA 2KR5A 2VSQA 1DV5A 4CA3A 2K94A 2EHSA 2JU1A 1L0HA 2FQ2A 2MF4A 2K2QA 5CZDB 3CE7A 2CNRA 2X2BA 2AFEA 2N50A 2N5IA 3EJDA 1HY8A 5EJDA 2KORA 3RG2A 2AVAA 2JGPA 1DNYA 2KG8A 2FACA 2LIUA 1OR5A 1VKUA 2KGAA 2KG6A 2FADA 3EJEA 2MR8A 2N6ZA 1HQBA 5KP6B 2FAEA 2GDXA 2CGQA 1AF8A 2L22A 2LOLA 4HKGA 1X3OA 4BPHA 2MY5A 2DNWA 4BPFA 2KGCA 4NEOA 2L9FA 2LMLA 4DG9A 2MD9A 2GDWA 3LMOA 2FHSC 2LIWA 5KP7B 3NY7B 2KOSA 1KLPA 2FVEA 2LKIA 2AF8A 1L0IA 4H2YC 2M5RA 4MRTC 2PNGA 1NQ4A 2EHTA 2JU2A 2KWLA 4PXHB 2FQ1A 5KP8B 2XZ1C 2FVFA 2LPKA 4R0MA 2AFDA 2KOOA 2K0YA 2QNWA 2XZ0D 4H2XC 4H2WC 2KW2A 2K0XA 1ACPA 2KGDA 2MVUA 2K92A 2MVVA 2L4BA
chains in the Genus database with same CATH superfamily
2KGEA 2KOQA 2VLPA 4U0DA 2N6YA 2BUOA 3H4EA 1KC8Q 3DS1A 3M1MA 2ROQA 5HGOA 3G29A 2KG9A 2KOPA 2OTLP 1DV5A 2VSQA 2GYKA 2GZJA 2JBGA 2EHSA 1QRJA 2E1MA 2QEXP 2K2QA 1UJZA 2OTJP 5CZDB 4COCA 2CNRA 1D1DA 2X2BA 3G21A 1YITP 1VQ7P 3CCSP 2PEJA 3EJDA 1HY8A 2AVAA 2KODA 2KG8A 3CC7P 1VKUA 2CWOA 1VQ9P 2KG6A 1A43A 3G1IA 2PEQA 1IUQA 5KP6B 2FAEA 1Q82Q 3Q20A 1YI2P 3RG6C 2EIAA 1GPJA 5HGLA 4XFYA 2VLNA 2JB0A 2KGCA 3CPWO 1VQ6P 3LMOA 3H47A 3G28A 2FVEA 3CCEP 1M90Q 2NO8A 2PENA 2PNGA 1YIJP 2QA4P 1K9MQ 1GXGA 3CC2P 3B5IA 2EG5A 4R0MA 2LPKA 2AFDA 2KOOA 2K0YA 3CCVP 1M6NA 3DS4A 1IMQA 3HYBA 2VLOA 1ZNVA 1E0HA 2WPTA 1A8OA 4IZ6A 2PEIA 1W2BO 4BPGA 1YHQP 2L0QA 1EIAA 3EJBA 2CQ8A 1AYIA 2FVAA 1ZMBA 3E2DA 4XROA 3GZMA 1K73Q 2LF4A 2JU1A 2MF4A 3H0DA 3CXCO 2XXMA 2AFEA 2N50A 2L6EA 2P9XA 5I4TG 2GZEA 2JGPA 3I55P 1Q81Q 2FACA 2ERHA 2FADA 4U0BA 3HZQA 2L22A 2LOLA 1RO0A 1X3OA 3G71P 1M74A 2M8NA 3DS5A 4XFZA 3G0VA 4U0EA 4NEOA 4DG9A 4XRQA 2FHSC 4F37A 1Q86Q 1VQMP 2KOSA 4COPA 3DS0A 1KLPA 3DPHA 1BAJA 1NQ4A 1VQPP 2JU2A 4PXHB 2EFJA 2DGYA 1BXIA 2QNWA 2XZ0D 3U43A 4H2XC 4H2WC 1ACPA 2KGDA 3P05A 3DTJA 2K92A 2MVVA 2N5HA 4U0CA 1YJWP 2LL8A 2PEMA 1JJ2O 4PWVB 2K5XA 1K8AQ 4PH1A 2JQ4A 1KD1Q 5EW5E 2N98A 2FQ0A 4QKOA 2GDYA 2LTEA 1EOQA 1VHNA 4IPYA 4CA3A 4XFXA 4UHPB 3GKLC 2N5IA 2JO0A 2LIUA 1OR5A 1QVGO 1AUMA 3EJEA 5BS1A 3MGEA 2MR8A 1UNKA 2N6ZA 3GJNA 1HQBA 1RNIA 2GDXA 2CGQA 1AF8A 3LRYA 4HKGA 1M6EX 5HGNA 4BPHA 2MY5A 1N8RQ 1QVFO 3CCRP 2DNWA 1E6JP 3VRLC 2L9FA 3CCJP 2MD9A 3WBHA 2LIWA 5KP7B 3NY7B 4PH0A 2PEKA 1L0IA 4H2YC 2M5RA 5JPAA 5DCKA 1GXHA 2EHTA 2M8PA 2FQ1A 4WYMA 2M8LA 3CMAP 2XV6A 1VQKP 4U0FA 2VLQA 3B4QA 3CD6P 7CEIA 2GZFA 2MVUA 2JYGA 2Z46A 4BPFA 2L4BA 5HV8A 5F2OA 1F80D 1MZ8A 2BHVA 2K93A 2CG5B 2Z44A 2MR7A 2XT1A 2GZGA 1M1KQ 1RO2A 5HVCA 3GZLA 3DS3A 1T8KA 2KR5A 1VQ8P 2K94A 1L0HA 3CCUP 4GR2A 2FQ2A 1YJ9P 4GR6A 3CE7A 1EMVA 1VQ5P 2ONTA 1VQOP 5EJDA 2KORA 3CC4P 3RG2A 1YJNP 1DNYA 2KGAA 2Z45A 3CCMP 3CCLP 1VQ4P 3G1GA 2JAZA 3CCQP 3G26A 1NJIQ 3CMEP 3OW2O 4U0AA 1S72P 2K0DX 2LMLA 2GDWA 5F2NA 2GZIA 3NTEA 1VQLP 4QNBA 2OARA 2LKIA 2AF8A 3DS2A 5BS2A 2JYLA 4MRTC 1Z6MA 2KWLA 3I56P 5HGMA 1K30A 5KP8B 2XZ1C 2FVFA 1FR2A 1Q7YQ 2PEOA 1CEIA 1VQNP 2KW2A 2K0XA 3G6EP 1KQSO 3G4SP 4M0IA 2PY8A 1IMPA 5F2KA
chains in the Genus database with same CATH topology
2N5HA 2KGEA 2KOQA 5HV8A 1F80D 4IZ6A 2LL8A 2N6YA 4PWVB 2K93A 2CG5B 4BPGA 2L0QA 2MR7A 2ROQA 2JQ4A 3EJBA 2CQ8A 2N98A 2FVAA 2FQ0A 2GDYA 2LTEA 5HVCA 2KG9A 3GZLA 2KOPA 1T8KA 3GZMA 2KR5A 2VSQA 1DV5A 4CA3A 2K94A 2EHSA 2JU1A 1L0HA 2FQ2A 2MF4A 2K2QA 5CZDB 3CE7A 2CNRA 2X2BA 2AFEA 2N50A 2N5IA 3EJDA 1HY8A 5EJDA 2KORA 3RG2A 2AVAA 2JGPA 1DNYA 2KG8A 2FACA 2LIUA 1OR5A 1VKUA 2KGAA 2KG6A 2FADA 3EJEA 2MR8A 2N6ZA 1HQBA 5KP6B 2FAEA 2GDXA 2CGQA 1AF8A 2L22A 2LOLA 4HKGA 1X3OA 4BPHA 2MY5A 2DNWA 4BPFA 2KGCA 4NEOA 2L9FA 2LMLA 4DG9A 2MD9A 2GDWA 3LMOA 2FHSC 2LIWA 5KP7B 3NY7B 2KOSA 1KLPA 2FVEA 2LKIA 2AF8A 1L0IA 4H2YC 2M5RA 4MRTC 2PNGA 1NQ4A 2EHTA 2JU2A 2KWLA 4PXHB 2FQ1A 5KP8B 2XZ1C 2FVFA 2LPKA 4R0MA 2AFDA 2KOOA 2K0YA 2QNWA 2XZ0D 4H2XC 4H2WC 2KW2A 2K0XA 1ACPA 2KGDA 2MVUA 2K92A 2MVVA 2L4BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2N5H A;  2KGE A;  2KOQ A;  5HV8 A;  1F80 D;  4IZ6 A;  2LL8 A;  2N6Y A;  4PWV B;  2K93 A;  2CG5 B;  4BPG A;  2L0Q A;  2MR7 A;  2ROQ A;  2JQ4 A;  3EJB A;  2CQ8 A;  2N98 A;  2FVA A;  2FQ0 A;  2GDY A;  2LTE A;  5HVC A;  2KG9 A;  3GZL A;  2KOP A;  1T8K A;  3GZM A;  2KR5 A;  2VSQ A;  1DV5 A;  4CA3 A;  2K94 A;  2EHS A;  2JU1 A;  1L0H A;  2FQ2 A;  2MF4 A;  2K2Q A;  5CZD B;  3CE7 A;  2CNR A;  2X2B A;  2AFE A;  2N50 A;  2N5I A;  3EJD A;  1HY8 A;  5EJD A;  2KOR A;  3RG2 A;  2AVA A;  2JGP A;  1DNY A;  2KG8 A;  2FAC A;  2LIU A;  1OR5 A;  1VKU A;  2KGA A;  2KG6 A;  2FAD A;  3EJE A;  2MR8 A;  2N6Z A;  1HQB A;  5KP6 B;  2FAE A;  2GDX A;  2CGQ A;  1AF8 A;  2L22 A;  2LOL A;  4HKG A;  1X3O A;  4BPH A;  2MY5 A;  2DNW A;  4BPF A;  2KGC A;  4NEO A;  2L9F A;  2LML A;  4DG9 A;  2MD9 A;  2GDW A;  3LMO A;  2FHS C;  2LIW A;  5KP7 B;  3NY7 B;  2KOS A;  1KLP A;  2FVE A;  2LKI A;  2AF8 A;  1L0I A;  4H2Y C;  2M5R A;  4MRT C;  2PNG A;  1NQ4 A;  2EHT A;  2JU2 A;  2KWL A;  4PXH B;  2FQ1 A;  5KP8 B;  2XZ1 C;  2FVF A;  2LPK A;  4R0M A;  2AFD A;  2KOO A;  2K0Y A;  2QNW A;  2XZ0 D;  4H2X C;  4H2W C;  2KW2 A;  2K0X A;  1ACP A;  2KGD A;  2MVU A;  2K92 A;  2MVV A;  2L4B A; 
#chains in the Genus database with same CATH topology
 2KGE A;  2KOQ A;  2VLP A;  4U0D A;  2N6Y A;  2BUO A;  3H4E A;  1KC8 Q;  3DS1 A;  3M1M A;  2ROQ A;  5HGO A;  3G29 A;  2KG9 A;  2KOP A;  2OTL P;  1DV5 A;  2VSQ A;  2GYK A;  2GZJ A;  2JBG A;  2EHS A;  1QRJ A;  2E1M A;  2QEX P;  2K2Q A;  1UJZ A;  2OTJ P;  5CZD B;  4COC A;  2CNR A;  1D1D A;  2X2B A;  3G21 A;  1YIT P;  1VQ7 P;  3CCS P;  2PEJ A;  3EJD A;  1HY8 A;  2AVA A;  2KOD A;  2KG8 A;  3CC7 P;  1VKU A;  2CWO A;  1VQ9 P;  2KG6 A;  1A43 A;  3G1I A;  2PEQ A;  1IUQ A;  5KP6 B;  2FAE A;  1Q82 Q;  3Q20 A;  1YI2 P;  3RG6 C;  2EIA A;  1GPJ A;  5HGL A;  4XFY A;  2VLN A;  2JB0 A;  2KGC A;  3CPW O;  1VQ6 P;  3LMO A;  3H47 A;  3G28 A;  2FVE A;  3CCE P;  1M90 Q;  2NO8 A;  2PEN A;  2PNG A;  1YIJ P;  2QA4 P;  1K9M Q;  1GXG A;  3CC2 P;  3B5I A;  2EG5 A;  4R0M A;  2LPK A;  2AFD A;  2KOO A;  2K0Y A;  3CCV P;  1M6N A;  3DS4 A;  1IMQ A;  3HYB A;  2VLO A;  1ZNV A;  1E0H A;  2WPT A;  1A8O A;  4IZ6 A;  2PEI A;  1W2B O;  4BPG A;  1YHQ P;  2L0Q A;  1EIA A;  3EJB A;  2CQ8 A;  1AYI A;  2FVA A;  1ZMB A;  3E2D A;  4XRO A;  3GZM A;  1K73 Q;  2LF4 A;  2JU1 A;  2MF4 A;  3H0D A;  3CXC O;  2XXM A;  2AFE A;  2N50 A;  2L6E A;  2P9X A;  5I4T G;  2GZE A;  2JGP A;  3I55 P;  1Q81 Q;  2FAC A;  2ERH A;  2FAD A;  4U0B A;  3HZQ A;  2L22 A;  2LOL A;  1RO0 A;  1X3O A;  3G71 P;  1M74 A;  2M8N A;  3DS5 A;  4XFZ A;  3G0V A;  4U0E A;  4NEO A;  4DG9 A;  4XRQ A;  2FHS C;  4F37 A;  1Q86 Q;  1VQM P;  2KOS A;  4COP A;  3DS0 A;  1KLP A;  3DPH A;  1BAJ A;  1NQ4 A;  1VQP P;  2JU2 A;  4PXH B;  2EFJ A;  2DGY A;  1BXI A;  2QNW A;  2XZ0 D;  3U43 A;  4H2X C;  4H2W C;  1ACP A;  2KGD A;  3P05 A;  3DTJ A;  2K92 A;  2MVV A;  2N5H A;  4U0C A;  1YJW P;  2LL8 A;  2PEM A;  1JJ2 O;  4PWV B;  2K5X A;  1K8A Q;  4PH1 A;  2JQ4 A;  1KD1 Q;  5EW5 E;  2N98 A;  2FQ0 A;  4QKO A;  2GDY A;  2LTE A;  1EOQ A;  1VHN A;  4IPY A;  4CA3 A;  4XFX A;  4UHP B;  3GKL C;  2N5I A;  2JO0 A;  2LIU A;  1OR5 A;  1QVG O;  1AUM A;  3EJE A;  5BS1 A;  3MGE A;  2MR8 A;  1UNK A;  2N6Z A;  3GJN A;  1HQB A;  1RNI A;  2GDX A;  2CGQ A;  1AF8 A;  3LRY A;  4HKG A;  1M6E X;  5HGN A;  4BPH A;  2MY5 A;  1N8R Q;  1QVF O;  3CCR P;  2DNW A;  1E6J P;  3VRL C;  2L9F A;  3CCJ P;  2MD9 A;  3WBH A;  2LIW A;  5KP7 B;  3NY7 B;  4PH0 A;  2PEK A;  1L0I A;  4H2Y C;  2M5R A;  5JPA A;  5DCK A;  1GXH A;  2EHT A;  2M8P A;  2FQ1 A;  4WYM A;  2M8L A;  3CMA P;  2XV6 A;  1VQK P;  4U0F A;  2VLQ A;  3B4Q A;  3CD6 P;  7CEI A;  2GZF A;  2MVU A;  2JYG A;  2Z46 A;  4BPF A;  2L4B A;  5HV8 A;  5F2O A;  1F80 D;  1MZ8 A;  2BHV A;  2K93 A;  2CG5 B;  2Z44 A;  2MR7 A;  2XT1 A;  2GZG A;  1M1K Q;  1RO2 A;  5HVC A;  3GZL A;  3DS3 A;  1T8K A;  2KR5 A;  1VQ8 P;  2K94 A;  1L0H A;  3CCU P;  4GR2 A;  2FQ2 A;  1YJ9 P;  4GR6 A;  3CE7 A;  1EMV A;  1VQ5 P;  2ONT A;  1VQO P;  5EJD A;  2KOR A;  3CC4 P;  3RG2 A;  1YJN P;  1DNY A;  2KGA A;  2Z45 A;  3CCM P;  3CCL P;  1VQ4 P;  3G1G A;  2JAZ A;  3CCQ P;  3G26 A;  1NJI Q;  3CME P;  3OW2 O;  4U0A A;  1S72 P;  2K0D X;  2LML A;  2GDW A;  5F2N A;  2GZI A;  3NTE A;  1VQL P;  4QNB A;  2OAR A;  2LKI A;  2AF8 A;  3DS2 A;  5BS2 A;  2JYL A;  4MRT C;  1Z6M A;  2KWL A;  3I56 P;  5HGM A;  1K30 A;  5KP8 B;  2XZ1 C;  2FVF A;  1FR2 A;  1Q7Y Q;  2PEO A;  1CEI A;  1VQN P;  2KW2 A;  2K0X A;  3G6E P;  1KQS O;  3G4S P;  4M0I A;  2PY8 A;  1IMP A;  5F2K A; 
#chains in the Genus database with same CATH homology
 2N5H A;  2KGE A;  2KOQ A;  5HV8 A;  1F80 D;  4IZ6 A;  2LL8 A;  2N6Y A;  4PWV B;  2K93 A;  2CG5 B;  4BPG A;  2L0Q A;  2MR7 A;  2ROQ A;  2JQ4 A;  3EJB A;  2CQ8 A;  2N98 A;  2FVA A;  2FQ0 A;  2GDY A;  2LTE A;  5HVC A;  2KG9 A;  3GZL A;  2KOP A;  1T8K A;  3GZM A;  2KR5 A;  2VSQ A;  1DV5 A;  4CA3 A;  2K94 A;  2EHS A;  2JU1 A;  1L0H A;  2FQ2 A;  2MF4 A;  2K2Q A;  5CZD B;  3CE7 A;  2CNR A;  2X2B A;  2AFE A;  2N50 A;  2N5I A;  3EJD A;  1HY8 A;  5EJD A;  2KOR A;  3RG2 A;  2AVA A;  2JGP A;  1DNY A;  2KG8 A;  2FAC A;  2LIU A;  1OR5 A;  1VKU A;  2KGA A;  2KG6 A;  2FAD A;  3EJE A;  2MR8 A;  2N6Z A;  1HQB A;  5KP6 B;  2FAE A;  2GDX A;  2CGQ A;  1AF8 A;  2L22 A;  2LOL A;  4HKG A;  1X3O A;  4BPH A;  2MY5 A;  2DNW A;  4BPF A;  2KGC A;  4NEO A;  2L9F A;  2LML A;  4DG9 A;  2MD9 A;  2GDW A;  3LMO A;  2FHS C;  2LIW A;  5KP7 B;  3NY7 B;  2KOS A;  1KLP A;  2FVE A;  2LKI A;  2AF8 A;  1L0I A;  4H2Y C;  2M5R A;  4MRT C;  2PNG A;  1NQ4 A;  2EHT A;  2JU2 A;  2KWL A;  4PXH B;  2FQ1 A;  5KP8 B;  2XZ1 C;  2FVF A;  2LPK A;  4R0M A;  2AFD A;  2KOO A;  2K0Y A;  2QNW A;  2XZ0 D;  4H2X C;  4H2W C;  2KW2 A;  2K0X A;  1ACP A;  2KGD A;  2MVU A;  2K92 A;  2MVV A;  2L4B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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