2K2QA

Complex structure of the external thioesterase of the surfactin-synthetase with a carrier domain
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
82
structure length
82
Chain Sequence
MGVTEAQYVAPTNAVESKLAEIWERVLGVSGIGILDNFFQIGGHSLKAMAVAAQVHREYQVELPLKVLFAQPTIKALAQYVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the selectivity of the external thioesterase of the surfactin synthetase.
pubmed doi rcsb
molecule tags Ligase/hydrolase
source organism Brevibacillus parabrevis
molecule keywords Tyrocidine synthetase 3 (Tyrocidine synthetase III)
total genus 14
structure length 82
sequence length 82
ec nomenclature
pdb deposition date 2008-04-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 2k2qA00
2GDYA 2CNRA 2EHTA 2AFDA 1NQ4A 2DNWA 2FQ2A 2FADA 2KGAA 2KWLA 2MR8A 2K0YA 2MD9A 4PWVB 1DNYA 2VSQA 2N5IA 2FQ0A 1KLPA 2L22A 2KW2A 2FVEA 4BPHA 2KG6A 2L0QA 2L9FA 2K0XA 2FQ1A 2LOLA 2JU2A 3EJDA 2N50A 2K2QA 2CQ8A 5CZDB 2K92A 2LL8A 4H2YC 2KG8A 4BPFA 4DG9A 2LKIA 5EJDA 4NEOA 2EHSA 5KP7B 5KP6B 1T8KA 2FAEA 2KGEA 3NY7B 4HKGA 2LIWA 2FHSC 2MY5A 2AVAA 2MVVA 2KGCA 2PNGA 2FVFA 2KOSA 3GZLA 1L0IA 2XZ1C 4IZ6A 2LIUA 2JGPA 2LTEA 1VKUA 3RG2A 2MR7A 2AF8A 2ROQA 2QNWA 2MVUA 1X3OA 2X2BA 2JQ4A 2KORA 2KR5A 2MF4A 2L4BA 1HY8A 2KGDA 5KP8B 1AF8A 2KOOA 1OR5A 2K94A 2N98A 2LPKA 4H2XC 2KG9A 3EJEA 2N5HA 3GZMA 5HV8A 2CG5B 3CE7A 2CGQA 2K93A 4H2WC 2N6YA 1F80D 4PXHB 2KOPA 4BPGA 1ACPA 2FACA 3EJBA 2AFEA 3LMOA 2FVAA 4MRTC 2GDWA 2GDXA 4R0MA 5HVCA 1DV5A 2N6ZA 2XZ0D 1L0HA 2LMLA 2M5RA 4CA3A 2JU1A 1HQBA 2KOQA
chains in the Genus database with same CATH superfamily
1NJIQ 2OTJP 2EHTA 1YIJP 2AFDA 3GJNA 3CCVP 2DNWA 4PWVB 2N5IA 1YJNP 5HGMA 3CCQP 1UJZA 4BPHA 2L0QA 3CCUP 2PENA 1YITP 2EFJA 3P05A 1VQ6P 4H2YC 3G4SP 2EIAA 4XRQA 3CCEP 4NEOA 2EHSA 3G29A 3G21A 3NY7B 2GYKA 2LIWA 3DS1A 2FHSC 4UHPB 2K5XA 3CMAP 3GKLC 2AVAA 3B5IA 5F2OA 3CCMP 3GZLA 1GXHA 2XZ1C 3E2DA 2MR7A 1K73Q 4XFXA 2LF4A 1ZMBA 1X3OA 1VQMP 2X2BA 4U0EA 5I4TG 4F37A 3I55P 4PH1A 1Q81Q 2K93A 4U0CA 4BPGA 2FACA 2ERHA 3LMOA 1VQLP 4U0AA 4MRTC 1FR2A 5HGNA 2XZ0D 3CC2P 1L0HA 1HQBA 2EG5A 1KQSO 2GDYA 5F2KA 2Z46A 1NQ4A 2FADA 2MR8A 3G28A 2P9XA 1DNYA 2GZGA 2BUOA 2FQ0A 4IPYA 7CEIA 1N8RQ 2KW2A 2VLQA 2LOLA 2JU2A 1EOQA 3EJDA 2N50A 1M1KQ 5F2NA 2K92A 2LL8A 2LKIA 3U43A 3G0VA 1T8KA 2FAEA 2KGEA 3DS4A 2JYGA 1YJ9P 2MVVA 2PNGA 5HGOA 2KOSA 3G26A 1Z6MA 2JGPA 4GR2A 2LTEA 4XROA 3CCSP 2ROQA 2QNWA 2MVUA 2PEOA 2KORA 1OR5A 1QRJA 5DCKA 3DPHA 3NTEA 5HV8A 1A43A 1K30A 4QNBA 1QVFO 4H2WC 1F80D 3CC7P 1Q7YQ 3CCJP 1YI2P 1ACPA 1VHNA 1VQ8P 2PEJA 2FVAA 1VQ7P 4XFZA 1RNIA 2QEXP 3CC4P 3G1IA 4R0MA 1DV5A 2GZIA 2N6ZA 1AYIA 3CXCO 1VQ5P 4CA3A 1QVGO 2JU1A 1RO2A 2KOQA 1EIAA 1RO0A 5JPAA 1GXGA 5BS2A 2KWLA 3WBHA 2K0YA 2VSQA 2XXMA 1KLPA 2FVEA 1UNKA 3HZQA 2KG6A 3CD6P 2GZJA 2L9FA 1D1DA 1K9MQ 4COPA 2K2QA 2JBGA 2DGYA 2WPTA 4BPFA 4DG9A 3DS2A 2PEQA 5EJDA 4U0DA 5KP7B 5KP6B 4HKGA 3I56P 3DS3A 4WYMA 1CEIA 2MY5A 1KD1Q 2KGCA 1AUMA 2FVFA 2OTLP 1M90Q 3HYBA 2LIUA 3G6EP 3VRLC 3CCLP 3RG2A 2AF8A 2JYLA 3MGEA 4QKOA 1IMQA 2KR5A 1HY8A 2KGDA 1AF8A 2KOOA 2QA4P 1Q82Q 3M1MA 2K94A 1VQ4P 2KODA 2LPKA 4M0IA 1K8AQ 4H2XC 2KG9A 2E1MA 3GZMA 1M74A 2PEKA 1YHQP 4U0FA 2KOPA 2JAZA 1W2BO 1VQNP 3G1GA 2JO0A 5HVCA 2L6EA 2VLNA 3OW2O 2OARA 3DS0A 3RG6C 1VQ9P 2PEIA 2M5RA 2KGAA 1GPJA 4U0BA 2CNRA 4XFYA 3H0DA 2JB0A 2VLPA 3CMEP 1IUQA 2FQ2A 3CCRP 2VLOA 2MD9A 4GR6A 1M6NA 2L22A 3LRYA 5BS1A 5EW5E 1E0HA 2K0XA 2FQ1A 3B4QA 2NO8A 1EMVA 2CQ8A 5CZDB 2M8NA 2KG8A 1VQKP 1ZNVA 2PEMA 1M6EX 2M8LA 3CPWO 1YJWP 2XV6A 1IMPA 1Q86Q 2BHVA 1VQOP 1L0IA 4IZ6A 4COCA 1VKUA 2CWOA 3DS5A 2M8PA 2ONTA 5HGLA 2JQ4A 2MF4A 2L4BA 1BAJA 5KP8B 2GZFA 1KC8Q 2XT1A 2N98A 2Z44A 1VQPP 1MZ8A 2GZEA 3EJEA 2N5HA 2CG5B 3CE7A 2CGQA 1JJ2O 3DTJA 2PY8A 2N6YA 4PXHB 4PH0A 3EJBA 1BXIA 3H4EA 2AFEA 2K0DX 3G71P 3H47A 2Z45A 2GDWA 2GDXA 1A8OA 1E6JP 2LMLA 3Q20A 1S72P
chains in the Genus database with same CATH topology
2GDYA 2CNRA 2EHTA 2AFDA 1NQ4A 2DNWA 2FQ2A 2FADA 2KGAA 2KWLA 2MR8A 2K0YA 2MD9A 4PWVB 1DNYA 2VSQA 2N5IA 2FQ0A 1KLPA 2L22A 2KW2A 2FVEA 4BPHA 2KG6A 2L0QA 2L9FA 2K0XA 2FQ1A 2LOLA 2JU2A 3EJDA 2N50A 2K2QA 2CQ8A 5CZDB 2K92A 2LL8A 4H2YC 2KG8A 4BPFA 4DG9A 2LKIA 5EJDA 4NEOA 2EHSA 5KP7B 5KP6B 1T8KA 2FAEA 2KGEA 3NY7B 4HKGA 2LIWA 2FHSC 2MY5A 2AVAA 2MVVA 2KGCA 2PNGA 2FVFA 2KOSA 3GZLA 1L0IA 2XZ1C 4IZ6A 2LIUA 2JGPA 2LTEA 1VKUA 3RG2A 2MR7A 2AF8A 2ROQA 2QNWA 2MVUA 1X3OA 2X2BA 2JQ4A 2KORA 2KR5A 2MF4A 2L4BA 1HY8A 2KGDA 5KP8B 1AF8A 2KOOA 1OR5A 2K94A 2N98A 2LPKA 4H2XC 2KG9A 3EJEA 2N5HA 3GZMA 5HV8A 2CG5B 3CE7A 2CGQA 2K93A 4H2WC 2N6YA 1F80D 4PXHB 2KOPA 4BPGA 1ACPA 2FACA 3EJBA 2AFEA 3LMOA 2FVAA 4MRTC 2GDWA 2GDXA 4R0MA 5HVCA 1DV5A 2N6ZA 2XZ0D 1L0HA 2LMLA 2M5RA 4CA3A 2JU1A 1HQBA 2KOQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GDY A;  2CNR A;  2EHT A;  2AFD A;  1NQ4 A;  2DNW A;  2FQ2 A;  2FAD A;  2KGA A;  2KWL A;  2MR8 A;  2K0Y A;  2MD9 A;  4PWV B;  1DNY A;  2VSQ A;  2N5I A;  2FQ0 A;  1KLP A;  2L22 A;  2KW2 A;  2FVE A;  4BPH A;  2KG6 A;  2L0Q A;  2L9F A;  2K0X A;  2FQ1 A;  2LOL A;  2JU2 A;  3EJD A;  2N50 A;  2K2Q A;  2CQ8 A;  5CZD B;  2K92 A;  2LL8 A;  4H2Y C;  2KG8 A;  4BPF A;  4DG9 A;  2LKI A;  5EJD A;  4NEO A;  2EHS A;  5KP7 B;  5KP6 B;  1T8K A;  2FAE A;  2KGE A;  3NY7 B;  4HKG A;  2LIW A;  2FHS C;  2MY5 A;  2AVA A;  2MVV A;  2KGC A;  2PNG A;  2FVF A;  2KOS A;  3GZL A;  1L0I A;  2XZ1 C;  4IZ6 A;  2LIU A;  2JGP A;  2LTE A;  1VKU A;  3RG2 A;  2MR7 A;  2AF8 A;  2ROQ A;  2QNW A;  2MVU A;  1X3O A;  2X2B A;  2JQ4 A;  2KOR A;  2KR5 A;  2MF4 A;  2L4B A;  1HY8 A;  2KGD A;  5KP8 B;  1AF8 A;  2KOO A;  1OR5 A;  2K94 A;  2N98 A;  2LPK A;  4H2X C;  2KG9 A;  3EJE A;  2N5H A;  3GZM A;  5HV8 A;  2CG5 B;  3CE7 A;  2CGQ A;  2K93 A;  4H2W C;  2N6Y A;  1F80 D;  4PXH B;  2KOP A;  4BPG A;  1ACP A;  2FAC A;  3EJB A;  2AFE A;  3LMO A;  2FVA A;  4MRT C;  2GDW A;  2GDX A;  4R0M A;  5HVC A;  1DV5 A;  2N6Z A;  2XZ0 D;  1L0H A;  2LML A;  2M5R A;  4CA3 A;  2JU1 A;  1HQB A;  2KOQ A; 
#chains in the Genus database with same CATH topology
 1NJI Q;  2OTJ P;  2EHT A;  1YIJ P;  2AFD A;  3GJN A;  3CCV P;  2DNW A;  4PWV B;  2N5I A;  1YJN P;  5HGM A;  3CCQ P;  1UJZ A;  4BPH A;  2L0Q A;  3CCU P;  2PEN A;  1YIT P;  2EFJ A;  3P05 A;  1VQ6 P;  4H2Y C;  3G4S P;  2EIA A;  4XRQ A;  3CCE P;  4NEO A;  2EHS A;  3G29 A;  3G21 A;  3NY7 B;  2GYK A;  2LIW A;  3DS1 A;  2FHS C;  4UHP B;  2K5X A;  3CMA P;  3GKL C;  2AVA A;  3B5I A;  5F2O A;  3CCM P;  3GZL A;  1GXH A;  2XZ1 C;  3E2D A;  2MR7 A;  1K73 Q;  4XFX A;  2LF4 A;  1ZMB A;  1X3O A;  1VQM P;  2X2B A;  4U0E A;  5I4T G;  4F37 A;  3I55 P;  4PH1 A;  1Q81 Q;  2K93 A;  4U0C A;  4BPG A;  2FAC A;  2ERH A;  3LMO A;  1VQL P;  4U0A A;  4MRT C;  1FR2 A;  5HGN A;  2XZ0 D;  3CC2 P;  1L0H A;  1HQB A;  2EG5 A;  1KQS O;  2GDY A;  5F2K A;  2Z46 A;  1NQ4 A;  2FAD A;  2MR8 A;  3G28 A;  2P9X A;  1DNY A;  2GZG A;  2BUO A;  2FQ0 A;  4IPY A;  7CEI A;  1N8R Q;  2KW2 A;  2VLQ A;  2LOL A;  2JU2 A;  1EOQ A;  3EJD A;  2N50 A;  1M1K Q;  5F2N A;  2K92 A;  2LL8 A;  2LKI A;  3U43 A;  3G0V A;  1T8K A;  2FAE A;  2KGE A;  3DS4 A;  2JYG A;  1YJ9 P;  2MVV A;  2PNG A;  5HGO A;  2KOS A;  3G26 A;  1Z6M A;  2JGP A;  4GR2 A;  2LTE A;  4XRO A;  3CCS P;  2ROQ A;  2QNW A;  2MVU A;  2PEO A;  2KOR A;  1OR5 A;  1QRJ A;  5DCK A;  3DPH A;  3NTE A;  5HV8 A;  1A43 A;  1K30 A;  4QNB A;  1QVF O;  4H2W C;  1F80 D;  3CC7 P;  1Q7Y Q;  3CCJ P;  1YI2 P;  1ACP A;  1VHN A;  1VQ8 P;  2PEJ A;  2FVA A;  1VQ7 P;  4XFZ A;  1RNI A;  2QEX P;  3CC4 P;  3G1I A;  4R0M A;  1DV5 A;  2GZI A;  2N6Z A;  1AYI A;  3CXC O;  1VQ5 P;  4CA3 A;  1QVG O;  2JU1 A;  1RO2 A;  2KOQ A;  1EIA A;  1RO0 A;  5JPA A;  1GXG A;  5BS2 A;  2KWL A;  3WBH A;  2K0Y A;  2VSQ A;  2XXM A;  1KLP A;  2FVE A;  1UNK A;  3HZQ A;  2KG6 A;  3CD6 P;  2GZJ A;  2L9F A;  1D1D A;  1K9M Q;  4COP A;  2K2Q A;  2JBG A;  2DGY A;  2WPT A;  4BPF A;  4DG9 A;  3DS2 A;  2PEQ A;  5EJD A;  4U0D A;  5KP7 B;  5KP6 B;  4HKG A;  3I56 P;  3DS3 A;  4WYM A;  1CEI A;  2MY5 A;  1KD1 Q;  2KGC A;  1AUM A;  2FVF A;  2OTL P;  1M90 Q;  3HYB A;  2LIU A;  3G6E P;  3VRL C;  3CCL P;  3RG2 A;  2AF8 A;  2JYL A;  3MGE A;  4QKO A;  1IMQ A;  2KR5 A;  1HY8 A;  2KGD A;  1AF8 A;  2KOO A;  2QA4 P;  1Q82 Q;  3M1M A;  2K94 A;  1VQ4 P;  2KOD A;  2LPK A;  4M0I A;  1K8A Q;  4H2X C;  2KG9 A;  2E1M A;  3GZM A;  1M74 A;  2PEK A;  1YHQ P;  4U0F A;  2KOP A;  2JAZ A;  1W2B O;  1VQN P;  3G1G A;  2JO0 A;  5HVC A;  2L6E A;  2VLN A;  3OW2 O;  2OAR A;  3DS0 A;  3RG6 C;  1VQ9 P;  2PEI A;  2M5R A;  2KGA A;  1GPJ A;  4U0B A;  2CNR A;  4XFY A;  3H0D A;  2JB0 A;  2VLP A;  3CME P;  1IUQ A;  2FQ2 A;  3CCR P;  2VLO A;  2MD9 A;  4GR6 A;  1M6N A;  2L22 A;  3LRY A;  5BS1 A;  5EW5 E;  1E0H A;  2K0X A;  2FQ1 A;  3B4Q A;  2NO8 A;  1EMV A;  2CQ8 A;  5CZD B;  2M8N A;  2KG8 A;  1VQK P;  1ZNV A;  2PEM A;  1M6E X;  2M8L A;  3CPW O;  1YJW P;  2XV6 A;  1IMP A;  1Q86 Q;  2BHV A;  1VQO P;  1L0I A;  4IZ6 A;  4COC A;  1VKU A;  2CWO A;  3DS5 A;  2M8P A;  2ONT A;  5HGL A;  2JQ4 A;  2MF4 A;  2L4B A;  1BAJ A;  5KP8 B;  2GZF A;  1KC8 Q;  2XT1 A;  2N98 A;  2Z44 A;  1VQP P;  1MZ8 A;  2GZE A;  3EJE A;  2N5H A;  2CG5 B;  3CE7 A;  2CGQ A;  1JJ2 O;  3DTJ A;  2PY8 A;  2N6Y A;  4PXH B;  4PH0 A;  3EJB A;  1BXI A;  3H4E A;  2AFE A;  2K0D X;  3G71 P;  3H47 A;  2Z45 A;  2GDW A;  2GDX A;  1A8O A;  1E6J P;  2LML A;  3Q20 A;  1S72 P; 
#chains in the Genus database with same CATH homology
 2GDY A;  2CNR A;  2EHT A;  2AFD A;  1NQ4 A;  2DNW A;  2FQ2 A;  2FAD A;  2KGA A;  2KWL A;  2MR8 A;  2K0Y A;  2MD9 A;  4PWV B;  1DNY A;  2VSQ A;  2N5I A;  2FQ0 A;  1KLP A;  2L22 A;  2KW2 A;  2FVE A;  4BPH A;  2KG6 A;  2L0Q A;  2L9F A;  2K0X A;  2FQ1 A;  2LOL A;  2JU2 A;  3EJD A;  2N50 A;  2K2Q A;  2CQ8 A;  5CZD B;  2K92 A;  2LL8 A;  4H2Y C;  2KG8 A;  4BPF A;  4DG9 A;  2LKI A;  5EJD A;  4NEO A;  2EHS A;  5KP7 B;  5KP6 B;  1T8K A;  2FAE A;  2KGE A;  3NY7 B;  4HKG A;  2LIW A;  2FHS C;  2MY5 A;  2AVA A;  2MVV A;  2KGC A;  2PNG A;  2FVF A;  2KOS A;  3GZL A;  1L0I A;  2XZ1 C;  4IZ6 A;  2LIU A;  2JGP A;  2LTE A;  1VKU A;  3RG2 A;  2MR7 A;  2AF8 A;  2ROQ A;  2QNW A;  2MVU A;  1X3O A;  2X2B A;  2JQ4 A;  2KOR A;  2KR5 A;  2MF4 A;  2L4B A;  1HY8 A;  2KGD A;  5KP8 B;  1AF8 A;  2KOO A;  1OR5 A;  2K94 A;  2N98 A;  2LPK A;  4H2X C;  2KG9 A;  3EJE A;  2N5H A;  3GZM A;  5HV8 A;  2CG5 B;  3CE7 A;  2CGQ A;  2K93 A;  4H2W C;  2N6Y A;  1F80 D;  4PXH B;  2KOP A;  4BPG A;  1ACP A;  2FAC A;  3EJB A;  2AFE A;  3LMO A;  2FVA A;  4MRT C;  2GDW A;  2GDX A;  4R0M A;  5HVC A;  1DV5 A;  2N6Z A;  2XZ0 D;  1L0H A;  2LML A;  2M5R A;  4CA3 A;  2JU1 A;  1HQB A;  2KOQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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