2KG8A

Nmr solution structures of malonyl acp from the actinorhodin polyketide synthase in streptomyces coelicolor
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
86
structure length
86
Chain Sequence
MATLLTTDDLRRALVESAGETDGTDLSGDFLDLRFEDIGYDSLALMETAARLESRYGVSIPDDVAGRVDTPRELLDLINGALAEAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
pubmed doi rcsb
molecule tags Biosynthetic protein
source organism Streptomyces coelicolor
molecule keywords Actinorhodin polyketide synthase acyl carrier protein
total genus 25
structure length 86
sequence length 86
ec nomenclature
pdb deposition date 2009-03-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 2kg8A00
2KOQA 4BPFA 2FVAA 1T8KA 3EJEA 2XZ0D 2JQ4A 2KG8A 2AVAA 3EJBA 2FQ0A 5HVCA 2FADA 2LMLA 4BPGA 2ROQA 4NEOA 1HQBA 2AFDA 2FACA 4R0MA 2LKIA 2GDWA 2CG5B 2DNWA 2KG9A 2MY5A 2N5HA 2N6ZA 2X2BA 2LTEA 5KP7B 1NQ4A 2GDYA 2CNRA 4PWVB 2N50A 2JU2A 1DNYA 1F80D 2K94A 2KOOA 2MD9A 2FQ1A 1ACPA 4H2XC 1AF8A 2LPKA 2MR7A 5KP6B 1KLPA 3GZMA 2QNWA 2K0YA 2MVUA 2EHSA 2L22A 5KP8B 4BPHA 2L9FA 2LL8A 5HV8A 2LIWA 2EHTA 2CGQA 1DV5A 1HY8A 4IZ6A 1OR5A 4HKGA 3RG2A 4PXHB 3GZLA 2FVEA 2KOSA 1VKUA 2XZ1C 2KGDA 2K2QA 2KORA 2KWLA 2N6YA 2LOLA 3NY7B 4DG9A 2GDXA 2M5RA 4H2WC 2KW2A 2N5IA 2KGCA 2AF8A 2VSQA 2JGPA 2L4BA 2MR8A 2FAEA 4MRTC 2KR5A 2FHSC 2FQ2A 2KG6A 5EJDA 2MVVA 2KGAA 2JU1A 2CQ8A 2KOPA 2LIUA 2PNGA 1L0IA 5CZDB 1X3OA 2AFEA 2FVFA 2L0QA 2K92A 3CE7A 1L0HA 2K93A 3EJDA 2MF4A 2N98A 3LMOA 2KGEA 4CA3A 4H2YC 2K0XA
chains in the Genus database with same CATH superfamily
2FVAA 1YJWP 3EJEA 1YHQP 3I56P 4U0DA 1RO2A 3EJBA 4F37A 2XV6A 1HQBA 5EW5E 3CC7P 2KG9A 2N6ZA 5I4TG 2EG5A 1DNYA 3G1IA 2GZEA 1VQMP 1NJIQ 1RO0A 2MR7A 1VQOP 1YIJP 1M74A 2PEOA 2MVUA 4GR6A 4XFXA 2L22A 3HZQA 1M6NA 2L9FA 4BPHA 1GXHA 2E1MA 1DV5A 1OR5A 3RG2A 1YI2P 1Q7YQ 2VLPA 3GZLA 3G1GA 1VKUA 3CCSP 4COCA 2K2QA 7CEIA 1GPJA 2KGCA 2AF8A 2VSQA 2LF4A 1K9MQ 3DS3A 3WBHA 3DS4A 2FAEA 2M8LA 4U0AA 2Z46A 1VHNA 2AFEA 3CCRP 4QNBA 1KD1Q 1M90Q 2OTJP 2KGEA 5HGOA 3LRYA 2QA4P 1T8KA 1YITP 2AVAA 2FADA 2LMLA 4BPGA 2ROQA 1VQKP 3CCLP 2MY5A 4QKOA 1VQ8P 3G71P 1NQ4A 2GDYA 2CNRA 3I55P 2N50A 2JBGA 2GZGA 2VLOA 2MD9A 2FQ1A 1ACPA 2LPKA 5KP6B 4COPA 2K0YA 2JAZA 3DS2A 2JO0A 3Q20A 3CMEP 4U0EA 3HYBA 1VQ4P 5HV8A 5HGMA 3CMAP 2LIWA 3B5IA 2EHTA 1FR2A 1KQSO 1VQ9P 3U43A 4IZ6A 4HKGA 2PEQA 5JPAA 4U0CA 2KORA 2N6YA 4DG9A 1QVFO 4H2WC 1ZMBA 2MR8A 2GYKA 2M8PA 2FHSC 3DPHA 5HGLA 1YJNP 2GZFA 3G6EP 2KG6A 1VQ5P 2MVVA 2KGAA 2JU1A 1N8RQ 1VQLP 5CZDB 2L0QA 2PY8A 2JYLA 2MF4A 2OARA 2N98A 1K8AQ 1ZNVA 2BUOA 1UJZA 3CXCO 2XZ0D 2JQ4A 1K73Q 4NEOA 4R0MA 3GJNA 2XT1A 2GDWA 2GZJA 2NO8A 2LTEA 5F2KA 4PWVB 5DCKA 5BS2A 3E2DA 3B4QA 1Q81Q 4XFZA 2VLNA 2JU2A 1M6EX 1F80D 2K94A 2VLQA 1AUMA 2K0DX 1UNKA 4GR2A 4H2XC 1W2BO 3G26A 2EHSA 4M0IA 5KP8B 1CEIA 1E0HA 3H0DA 3DS0A 2CGQA 3H4EA 2PEJA 1EIAA 2XXMA 2FVEA 2ERHA 4XFYA 1Z6MA 3G21A 1D1DA 2KWLA 2LOLA 5F2NA 2GDXA 3CD6P 2N5IA 2JGPA 2Z44A 2JYGA 1YJ9P 3G4SP 2L6EA 1VQNP 2PEIA 5EJDA 1E6JP 3CCMP 2PNGA 1VQPP 3GKLC 3G29A 2M8NA 5F2OA 1X3OA 3CPWO 2FVFA 3CE7A 1GXGA 2EIAA 1S72P 2K93A 3CCVP 3EJDA 2DGYA 2WPTA 1VQ7P 3CC4P 4WYMA 1IMQA 2KOQA 2PEMA 4BPFA 3CCJP 2Z45A 2KG8A 2FQ0A 5HVCA 2KODA 2JB0A 1VQ6P 5HGNA 2AFDA 3CCUP 2FACA 3DS5A 2LKIA 3MGEA 4U0BA 1Q82Q 2CG5B 2DNWA 2N5HA 4XROA 1JJ2O 2X2BA 1IUQA 5KP7B 2PEKA 2OTLP 1AYIA 3OW2O 1Q86Q 2P9XA 2KOOA 3M1MA 1AF8A 2ONTA 1KLPA 3CCQP 2PENA 3GZMA 4U0FA 5BS1A 1MZ8A 2QNWA 1BXIA 3G28A 1QRJA 1IMPA 4XRQA 2LL8A 3NTEA 1HY8A 4IPYA 3H47A 3CC2P 3P05A 4PXHB 2KOSA 2XZ1C 2KGDA 1A8OA 1A43A 2EFJA 2GZIA 3NY7B 2M5RA 2KW2A 4UHPB 2K5XA 2QEXP 1QVGO 2L4BA 2CWOA 3DS1A 4PH0A 4MRTC 2KR5A 2FQ2A 3RG6C 1KC8Q 1EOQA 2CQ8A 2KOPA 2LIUA 3CCEP 1L0IA 3VRLC 1RNIA 1M1KQ 2K92A 3DTJA 1K30A 1EMVA 1L0HA 4PH1A 3LMOA 1BAJA 3G0VA 4CA3A 2BHVA 4H2YC 2K0XA
chains in the Genus database with same CATH topology
2KOQA 4BPFA 2FVAA 1T8KA 3EJEA 2XZ0D 2JQ4A 2KG8A 2AVAA 3EJBA 2FQ0A 5HVCA 2FADA 2LMLA 4BPGA 2ROQA 4NEOA 1HQBA 2AFDA 2FACA 4R0MA 2LKIA 2GDWA 2CG5B 2DNWA 2KG9A 2MY5A 2N5HA 2N6ZA 2X2BA 2LTEA 5KP7B 1NQ4A 2GDYA 2CNRA 4PWVB 2N50A 2JU2A 1DNYA 1F80D 2K94A 2KOOA 2MD9A 2FQ1A 1ACPA 4H2XC 1AF8A 2LPKA 2MR7A 5KP6B 1KLPA 3GZMA 2QNWA 2K0YA 2MVUA 2EHSA 2L22A 5KP8B 4BPHA 2L9FA 2LL8A 5HV8A 2LIWA 2EHTA 2CGQA 1DV5A 1HY8A 4IZ6A 1OR5A 4HKGA 3RG2A 4PXHB 3GZLA 2FVEA 2KOSA 1VKUA 2XZ1C 2KGDA 2K2QA 2KORA 2KWLA 2N6YA 2LOLA 3NY7B 4DG9A 2GDXA 2M5RA 4H2WC 2KW2A 2N5IA 2KGCA 2AF8A 2VSQA 2JGPA 2L4BA 2MR8A 2FAEA 4MRTC 2KR5A 2FHSC 2FQ2A 2KG6A 5EJDA 2MVVA 2KGAA 2JU1A 2CQ8A 2KOPA 2LIUA 2PNGA 1L0IA 5CZDB 1X3OA 2AFEA 2FVFA 2L0QA 2K92A 3CE7A 1L0HA 2K93A 3EJDA 2MF4A 2N98A 3LMOA 2KGEA 4CA3A 4H2YC 2K0XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KOQ A;  4BPF A;  2FVA A;  1T8K A;  3EJE A;  2XZ0 D;  2JQ4 A;  2KG8 A;  2AVA A;  3EJB A;  2FQ0 A;  5HVC A;  2FAD A;  2LML A;  4BPG A;  2ROQ A;  4NEO A;  1HQB A;  2AFD A;  2FAC A;  4R0M A;  2LKI A;  2GDW A;  2CG5 B;  2DNW A;  2KG9 A;  2MY5 A;  2N5H A;  2N6Z A;  2X2B A;  2LTE A;  5KP7 B;  1NQ4 A;  2GDY A;  2CNR A;  4PWV B;  2N50 A;  2JU2 A;  1DNY A;  1F80 D;  2K94 A;  2KOO A;  2MD9 A;  2FQ1 A;  1ACP A;  4H2X C;  1AF8 A;  2LPK A;  2MR7 A;  5KP6 B;  1KLP A;  3GZM A;  2QNW A;  2K0Y A;  2MVU A;  2EHS A;  2L22 A;  5KP8 B;  4BPH A;  2L9F A;  2LL8 A;  5HV8 A;  2LIW A;  2EHT A;  2CGQ A;  1DV5 A;  1HY8 A;  4IZ6 A;  1OR5 A;  4HKG A;  3RG2 A;  4PXH B;  3GZL A;  2FVE A;  2KOS A;  1VKU A;  2XZ1 C;  2KGD A;  2K2Q A;  2KOR A;  2KWL A;  2N6Y A;  2LOL A;  3NY7 B;  4DG9 A;  2GDX A;  2M5R A;  4H2W C;  2KW2 A;  2N5I A;  2KGC A;  2AF8 A;  2VSQ A;  2JGP A;  2L4B A;  2MR8 A;  2FAE A;  4MRT C;  2KR5 A;  2FHS C;  2FQ2 A;  2KG6 A;  5EJD A;  2MVV A;  2KGA A;  2JU1 A;  2CQ8 A;  2KOP A;  2LIU A;  2PNG A;  1L0I A;  5CZD B;  1X3O A;  2AFE A;  2FVF A;  2L0Q A;  2K92 A;  3CE7 A;  1L0H A;  2K93 A;  3EJD A;  2MF4 A;  2N98 A;  3LMO A;  2KGE A;  4CA3 A;  4H2Y C;  2K0X A; 
#chains in the Genus database with same CATH topology
 2FVA A;  1YJW P;  3EJE A;  1YHQ P;  3I56 P;  4U0D A;  1RO2 A;  3EJB A;  4F37 A;  2XV6 A;  1HQB A;  5EW5 E;  3CC7 P;  2KG9 A;  2N6Z A;  5I4T G;  2EG5 A;  1DNY A;  3G1I A;  2GZE A;  1VQM P;  1NJI Q;  1RO0 A;  2MR7 A;  1VQO P;  1YIJ P;  1M74 A;  2PEO A;  2MVU A;  4GR6 A;  4XFX A;  2L22 A;  3HZQ A;  1M6N A;  2L9F A;  4BPH A;  1GXH A;  2E1M A;  1DV5 A;  1OR5 A;  3RG2 A;  1YI2 P;  1Q7Y Q;  2VLP A;  3GZL A;  3G1G A;  1VKU A;  3CCS P;  4COC A;  2K2Q A;  7CEI A;  1GPJ A;  2KGC A;  2AF8 A;  2VSQ A;  2LF4 A;  1K9M Q;  3DS3 A;  3WBH A;  3DS4 A;  2FAE A;  2M8L A;  4U0A A;  2Z46 A;  1VHN A;  2AFE A;  3CCR P;  4QNB A;  1KD1 Q;  1M90 Q;  2OTJ P;  2KGE A;  5HGO A;  3LRY A;  2QA4 P;  1T8K A;  1YIT P;  2AVA A;  2FAD A;  2LML A;  4BPG A;  2ROQ A;  1VQK P;  3CCL P;  2MY5 A;  4QKO A;  1VQ8 P;  3G71 P;  1NQ4 A;  2GDY A;  2CNR A;  3I55 P;  2N50 A;  2JBG A;  2GZG A;  2VLO A;  2MD9 A;  2FQ1 A;  1ACP A;  2LPK A;  5KP6 B;  4COP A;  2K0Y A;  2JAZ A;  3DS2 A;  2JO0 A;  3Q20 A;  3CME P;  4U0E A;  3HYB A;  1VQ4 P;  5HV8 A;  5HGM A;  3CMA P;  2LIW A;  3B5I A;  2EHT A;  1FR2 A;  1KQS O;  1VQ9 P;  3U43 A;  4IZ6 A;  4HKG A;  2PEQ A;  5JPA A;  4U0C A;  2KOR A;  2N6Y A;  4DG9 A;  1QVF O;  4H2W C;  1ZMB A;  2MR8 A;  2GYK A;  2M8P A;  2FHS C;  3DPH A;  5HGL A;  1YJN P;  2GZF A;  3G6E P;  2KG6 A;  1VQ5 P;  2MVV A;  2KGA A;  2JU1 A;  1N8R Q;  1VQL P;  5CZD B;  2L0Q A;  2PY8 A;  2JYL A;  2MF4 A;  2OAR A;  2N98 A;  1K8A Q;  1ZNV A;  2BUO A;  1UJZ A;  3CXC O;  2XZ0 D;  2JQ4 A;  1K73 Q;  4NEO A;  4R0M A;  3GJN A;  2XT1 A;  2GDW A;  2GZJ A;  2NO8 A;  2LTE A;  5F2K A;  4PWV B;  5DCK A;  5BS2 A;  3E2D A;  3B4Q A;  1Q81 Q;  4XFZ A;  2VLN A;  2JU2 A;  1M6E X;  1F80 D;  2K94 A;  2VLQ A;  1AUM A;  2K0D X;  1UNK A;  4GR2 A;  4H2X C;  1W2B O;  3G26 A;  2EHS A;  4M0I A;  5KP8 B;  1CEI A;  1E0H A;  3H0D A;  3DS0 A;  2CGQ A;  3H4E A;  2PEJ A;  1EIA A;  2XXM A;  2FVE A;  2ERH A;  4XFY A;  1Z6M A;  3G21 A;  1D1D A;  2KWL A;  2LOL A;  5F2N A;  2GDX A;  3CD6 P;  2N5I A;  2JGP A;  2Z44 A;  2JYG A;  1YJ9 P;  3G4S P;  2L6E A;  1VQN P;  2PEI A;  5EJD A;  1E6J P;  3CCM P;  2PNG A;  1VQP P;  3GKL C;  3G29 A;  2M8N A;  5F2O A;  1X3O A;  3CPW O;  2FVF A;  3CE7 A;  1GXG A;  2EIA A;  1S72 P;  2K93 A;  3CCV P;  3EJD A;  2DGY A;  2WPT A;  1VQ7 P;  3CC4 P;  4WYM A;  1IMQ A;  2KOQ A;  2PEM A;  4BPF A;  3CCJ P;  2Z45 A;  2KG8 A;  2FQ0 A;  5HVC A;  2KOD A;  2JB0 A;  1VQ6 P;  5HGN A;  2AFD A;  3CCU P;  2FAC A;  3DS5 A;  2LKI A;  3MGE A;  4U0B A;  1Q82 Q;  2CG5 B;  2DNW A;  2N5H A;  4XRO A;  1JJ2 O;  2X2B A;  1IUQ A;  5KP7 B;  2PEK A;  2OTL P;  1AYI A;  3OW2 O;  1Q86 Q;  2P9X A;  2KOO A;  3M1M A;  1AF8 A;  2ONT A;  1KLP A;  3CCQ P;  2PEN A;  3GZM A;  4U0F A;  5BS1 A;  1MZ8 A;  2QNW A;  1BXI A;  3G28 A;  1QRJ A;  1IMP A;  4XRQ A;  2LL8 A;  3NTE A;  1HY8 A;  4IPY A;  3H47 A;  3CC2 P;  3P05 A;  4PXH B;  2KOS A;  2XZ1 C;  2KGD A;  1A8O A;  1A43 A;  2EFJ A;  2GZI A;  3NY7 B;  2M5R A;  2KW2 A;  4UHP B;  2K5X A;  2QEX P;  1QVG O;  2L4B A;  2CWO A;  3DS1 A;  4PH0 A;  4MRT C;  2KR5 A;  2FQ2 A;  3RG6 C;  1KC8 Q;  1EOQ A;  2CQ8 A;  2KOP A;  2LIU A;  3CCE P;  1L0I A;  3VRL C;  1RNI A;  1M1K Q;  2K92 A;  3DTJ A;  1K30 A;  1EMV A;  1L0H A;  4PH1 A;  3LMO A;  1BAJ A;  3G0V A;  4CA3 A;  2BHV A;  4H2Y C;  2K0X A; 
#chains in the Genus database with same CATH homology
 2KOQ A;  4BPF A;  2FVA A;  1T8K A;  3EJE A;  2XZ0 D;  2JQ4 A;  2KG8 A;  2AVA A;  3EJB A;  2FQ0 A;  5HVC A;  2FAD A;  2LML A;  4BPG A;  2ROQ A;  4NEO A;  1HQB A;  2AFD A;  2FAC A;  4R0M A;  2LKI A;  2GDW A;  2CG5 B;  2DNW A;  2KG9 A;  2MY5 A;  2N5H A;  2N6Z A;  2X2B A;  2LTE A;  5KP7 B;  1NQ4 A;  2GDY A;  2CNR A;  4PWV B;  2N50 A;  2JU2 A;  1DNY A;  1F80 D;  2K94 A;  2KOO A;  2MD9 A;  2FQ1 A;  1ACP A;  4H2X C;  1AF8 A;  2LPK A;  2MR7 A;  5KP6 B;  1KLP A;  3GZM A;  2QNW A;  2K0Y A;  2MVU A;  2EHS A;  2L22 A;  5KP8 B;  4BPH A;  2L9F A;  2LL8 A;  5HV8 A;  2LIW A;  2EHT A;  2CGQ A;  1DV5 A;  1HY8 A;  4IZ6 A;  1OR5 A;  4HKG A;  3RG2 A;  4PXH B;  3GZL A;  2FVE A;  2KOS A;  1VKU A;  2XZ1 C;  2KGD A;  2K2Q A;  2KOR A;  2KWL A;  2N6Y A;  2LOL A;  3NY7 B;  4DG9 A;  2GDX A;  2M5R A;  4H2W C;  2KW2 A;  2N5I A;  2KGC A;  2AF8 A;  2VSQ A;  2JGP A;  2L4B A;  2MR8 A;  2FAE A;  4MRT C;  2KR5 A;  2FHS C;  2FQ2 A;  2KG6 A;  5EJD A;  2MVV A;  2KGA A;  2JU1 A;  2CQ8 A;  2KOP A;  2LIU A;  2PNG A;  1L0I A;  5CZD B;  1X3O A;  2AFE A;  2FVF A;  2L0Q A;  2K92 A;  3CE7 A;  1L0H A;  2K93 A;  3EJD A;  2MF4 A;  2N98 A;  3LMO A;  2KGE A;  4CA3 A;  4H2Y C;  2K0X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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