2KGEA

Nmr solution structures of 3,5-dioxohexyl acp (a triketide mimic) from the actinorhodin polyketide synthase in streptomyces coelicolor
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
86
structure length
86
Chain Sequence
MATLLTTDDLRRALVESAGETDGTDLSGDFLDLRFEDIGYDSLALMETAARLESRYGVSIPDDVAGRVDTPRELLDLINGALAEAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
pubmed doi rcsb
molecule tags Biosynthetic protein
source organism Streptomyces coelicolor
molecule keywords Actinorhodin polyketide synthase acyl carrier protein
total genus 22
structure length 86
sequence length 86
ec nomenclature
pdb deposition date 2009-03-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 2kgeA00
2LIWA 3CE7A 2N50A 1X3OA 2KORA 5KP8B 2KR5A 2KOOA 2X2BA 2N6YA 2AFEA 3NY7B 2LL8A 2FHSC 2KOQA 2KOPA 4H2YC 2EHSA 3EJEA 2JQ4A 4R0MA 1L0IA 4PXHB 5HV8A 4H2XC 5HVCA 2M5RA 2MY5A 1OR5A 2JGPA 2KWLA 2K2QA 2CG5B 2KW2A 2PNGA 4BPGA 2FADA 2L4BA 2K94A 2CQ8A 4MRTC 2MF4A 1ACPA 2KG9A 5KP7B 2QNWA 2KG6A 2K0XA 2FVAA 1F80D 2LKIA 3RG2A 1L0HA 2MR7A 2XZ0D 2GDYA 1KLPA 2KOSA 2K92A 2FAEA 2VSQA 2L0QA 4BPHA 2KGEA 2FQ0A 3LMOA 2MVVA 1DNYA 2FVFA 2K93A 2MD9A 1T8KA 2LTEA 2N5IA 2AVAA 5KP6B 2N6ZA 1VKUA 1NQ4A 3GZLA 5CZDB 2N5HA 2LMLA 2KGAA 5EJDA 4BPFA 1HY8A 2DNWA 2MVUA 2N98A 4CA3A 4DG9A 3GZMA 1DV5A 2FQ2A 2LIUA 2LOLA 2KGCA 2CNRA 2FQ1A 2LPKA 2L22A 3EJBA 2GDWA 2ROQA 4PWVB 4H2WC 2AF8A 2AFDA 3EJDA 2GDXA 1HQBA 2JU1A 2FACA 2MR8A 4NEOA 1AF8A 2FVEA 2CGQA 2L9FA 2XZ1C 2KGDA 2KG8A 4HKGA 2JU2A 2K0YA 4IZ6A 2EHTA
chains in the Genus database with same CATH superfamily
1IMPA 2CWOA 1D1DA 1X3OA 2PEIA 5KP8B 3G28A 3NY7B 2OTLP 2KOQA 5BS2A 3CXCO 1QRJA 4COCA 2JQ4A 4R0MA 1M6EX 1L0IA 1E0HA 1VQ4P 2M5RA 1OR5A 1VQ7P 2JGPA 1Q86Q 3CC2P 1EIAA 2K2QA 4U0EA 2FADA 3B4QA 4MRTC 1ACPA 5HGMA 4PH1A 2M8PA 2LF4A 2FVAA 2LKIA 2MR7A 1K8AQ 2VLNA 1M74A 1KLPA 2KOSA 4QKOA 1KC8Q 2FAEA 2L0QA 2KGEA 1M1KQ 3G1IA 2XT1A 1T8KA 2LTEA 1YJNP 2N6ZA 5CZDB 3CCSP 1HY8A 2DNWA 2MVUA 2N98A 4DG9A 2JB0A 1VQKP 4GR6A 1Z6MA 2FQ2A 2WPTA 1VQNP 1Q82Q 4F37A 2L22A 2QA4P 2GDWA 3GKLC 2K0DX 3VRLC 1RNIA 2FACA 2M8NA 3DS2A 1AF8A 3Q20A 3CCVP 2CGQA 2KGDA 1GXGA 2PEKA 2KG8A 4HKGA 2GYKA 3CD6P 2QNWA 2EHTA 1YIJP 3G21A 2KR5A 4XFZA 4XFYA 2KOOA 1JJ2O 2N6YA 4U0AA 2AFEA 2M8LA 2LL8A 2XV6A 2KOPA 1Q81Q 5BS1A 4PXHB 5HV8A 5HVCA 2GZIA 2MY5A 1VQLP 4PH0A 3G29A 2EG5A 2OARA 2CG5B 1BXIA 1ZNVA 2PEMA 1W2BO 4U0CA 1F80D 3GJNA 3RG2A 4GR2A 2GDYA 2JYLA 5F2KA 2E1MA 3P05A 1YHQP 2EFJA 3LMOA 3G4SP 2QEXP 2MD9A 3DS0A 2OTJP 2PEJA 3G0VA 4IPYA 3GZLA 3CCEP 2N5HA 2LMLA 2KGAA 1YI2P 1M6NA 2P9XA 3G1GA 4CA3A 3OW2O 2EIAA 2JAZA 2LIUA 2LOLA 1QVFO 2FQ1A 3EJBA 1VHNA 2ROQA 3I56P 1BAJA 1VQ5P 5EW5E 1VQ9P 3CPWO 2GDXA 1E6JP 2PY8A 2JU1A 2MR8A 2FVEA 1MZ8A 2ERHA 1VQOP 2XZ1C 2VLOA 4M0IA 2JU2A 1ZMBA 4IZ6A 3DS5A 2LIWA 3CE7A 2PEQA 3M1MA 2N50A 4U0FA 2GZEA 1N8RQ 2VLQA 1YITP 3CCUP 2GZJA 3DTJA 2Z45A 4H2YC 3CCQP 3EJEA 5JPAA 3CC7P 2PNGA 2L4BA 2CQ8A 1KD1Q 2MF4A 2KG9A 5KP7B 2L6EA 3E2DA 5HGNA 1L0HA 3MGEA 2VSQA 2GZFA 4BPHA 2FQ0A 4WYMA 7CEIA 2MVVA 1DNYA 1A8OA 2FVFA 3CMEP 3NTEA 3CCJP 4XROA 2K93A 2N5IA 1S72P 1YJ9P 1VKUA 1NQ4A 4COPA 5EJDA 4BPFA 4U0BA 2DGYA 4XRQA 1DV5A 2KGCA 2CNRA 3DS3A 2JYGA 1VQPP 3RG6C 4PWVB 3H4EA 4H2WC 1K73Q 5HGLA 1AYIA 3HYBA 4QNBA 2AFDA 2PENA 5F2NA 2JBGA 1AUMA 4NEOA 3B5IA 3CCLP 1NJIQ 3CCMP 3H0DA 4U0DA 3H47A 1YJWP 2KODA 1K30A 4UHPB 3DS1A 1IMQA 2KORA 2X2BA 1CEIA 1VQMP 2FHSC 4XFXA 5I4TG 2EHSA 1QVGO 4H2XC 3G71P 2BUOA 2KWLA 2KW2A 1VQ8P 1Q7YQ 4BPGA 5HGOA 2K94A 2JO0A 1K9MQ 5DCKA 2KG6A 1GPJA 2K0XA 1IUQA 3CMAP 1KQSO 3HZQA 2BHVA 1FR2A 2XZ0D 5F2OA 2Z46A 2K92A 2GZGA 1RO2A 1A43A 2VLPA 2AVAA 5KP6B 3DPHA 2ONTA 1GXHA 3WBHA 1M90Q 1EMVA 3U43A 1VQ6P 1UJZA 3CCRP 3GZMA 2XXMA 3G26A 2LPKA 3CC4P 1EOQA 2Z44A 2K5XA 2AF8A 3EJDA 2NO8A 1HQBA 3I55P 3G6EP 2L9FA 1RO0A 2PEOA 1UNKA 3DS4A 2K0YA 3LRYA
chains in the Genus database with same CATH topology
2LIWA 3CE7A 2N50A 1X3OA 2KORA 5KP8B 2KR5A 2KOOA 2X2BA 2N6YA 2AFEA 3NY7B 2LL8A 2FHSC 2KOQA 2KOPA 4H2YC 2EHSA 3EJEA 2JQ4A 4R0MA 1L0IA 4PXHB 5HV8A 4H2XC 5HVCA 2M5RA 2MY5A 1OR5A 2JGPA 2KWLA 2K2QA 2CG5B 2KW2A 2PNGA 4BPGA 2FADA 2L4BA 2K94A 2CQ8A 4MRTC 2MF4A 1ACPA 2KG9A 5KP7B 2QNWA 2KG6A 2K0XA 2FVAA 1F80D 2LKIA 3RG2A 1L0HA 2MR7A 2XZ0D 2GDYA 1KLPA 2KOSA 2K92A 2FAEA 2VSQA 2L0QA 4BPHA 2KGEA 2FQ0A 3LMOA 2MVVA 1DNYA 2FVFA 2K93A 2MD9A 1T8KA 2LTEA 2N5IA 2AVAA 5KP6B 2N6ZA 1VKUA 1NQ4A 3GZLA 5CZDB 2N5HA 2LMLA 2KGAA 5EJDA 4BPFA 1HY8A 2DNWA 2MVUA 2N98A 4CA3A 4DG9A 3GZMA 1DV5A 2FQ2A 2LIUA 2LOLA 2KGCA 2CNRA 2FQ1A 2LPKA 2L22A 3EJBA 2GDWA 2ROQA 4PWVB 4H2WC 2AF8A 2AFDA 3EJDA 2GDXA 1HQBA 2JU1A 2FACA 2MR8A 4NEOA 1AF8A 2FVEA 2CGQA 2L9FA 2XZ1C 2KGDA 2KG8A 4HKGA 2JU2A 2K0YA 4IZ6A 2EHTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LIW A;  3CE7 A;  2N50 A;  1X3O A;  2KOR A;  5KP8 B;  2KR5 A;  2KOO A;  2X2B A;  2N6Y A;  2AFE A;  3NY7 B;  2LL8 A;  2FHS C;  2KOQ A;  2KOP A;  4H2Y C;  2EHS A;  3EJE A;  2JQ4 A;  4R0M A;  1L0I A;  4PXH B;  5HV8 A;  4H2X C;  5HVC A;  2M5R A;  2MY5 A;  1OR5 A;  2JGP A;  2KWL A;  2K2Q A;  2CG5 B;  2KW2 A;  2PNG A;  4BPG A;  2FAD A;  2L4B A;  2K94 A;  2CQ8 A;  4MRT C;  2MF4 A;  1ACP A;  2KG9 A;  5KP7 B;  2QNW A;  2KG6 A;  2K0X A;  2FVA A;  1F80 D;  2LKI A;  3RG2 A;  1L0H A;  2MR7 A;  2XZ0 D;  2GDY A;  1KLP A;  2KOS A;  2K92 A;  2FAE A;  2VSQ A;  2L0Q A;  4BPH A;  2KGE A;  2FQ0 A;  3LMO A;  2MVV A;  1DNY A;  2FVF A;  2K93 A;  2MD9 A;  1T8K A;  2LTE A;  2N5I A;  2AVA A;  5KP6 B;  2N6Z A;  1VKU A;  1NQ4 A;  3GZL A;  5CZD B;  2N5H A;  2LML A;  2KGA A;  5EJD A;  4BPF A;  1HY8 A;  2DNW A;  2MVU A;  2N98 A;  4CA3 A;  4DG9 A;  3GZM A;  1DV5 A;  2FQ2 A;  2LIU A;  2LOL A;  2KGC A;  2CNR A;  2FQ1 A;  2LPK A;  2L22 A;  3EJB A;  2GDW A;  2ROQ A;  4PWV B;  4H2W C;  2AF8 A;  2AFD A;  3EJD A;  2GDX A;  1HQB A;  2JU1 A;  2FAC A;  2MR8 A;  4NEO A;  1AF8 A;  2FVE A;  2CGQ A;  2L9F A;  2XZ1 C;  2KGD A;  2KG8 A;  4HKG A;  2JU2 A;  2K0Y A;  4IZ6 A;  2EHT A; 
#chains in the Genus database with same CATH topology
 1IMP A;  2CWO A;  1D1D A;  1X3O A;  2PEI A;  5KP8 B;  3G28 A;  3NY7 B;  2OTL P;  2KOQ A;  5BS2 A;  3CXC O;  1QRJ A;  4COC A;  2JQ4 A;  4R0M A;  1M6E X;  1L0I A;  1E0H A;  1VQ4 P;  2M5R A;  1OR5 A;  1VQ7 P;  2JGP A;  1Q86 Q;  3CC2 P;  1EIA A;  2K2Q A;  4U0E A;  2FAD A;  3B4Q A;  4MRT C;  1ACP A;  5HGM A;  4PH1 A;  2M8P A;  2LF4 A;  2FVA A;  2LKI A;  2MR7 A;  1K8A Q;  2VLN A;  1M74 A;  1KLP A;  2KOS A;  4QKO A;  1KC8 Q;  2FAE A;  2L0Q A;  2KGE A;  1M1K Q;  3G1I A;  2XT1 A;  1T8K A;  2LTE A;  1YJN P;  2N6Z A;  5CZD B;  3CCS P;  1HY8 A;  2DNW A;  2MVU A;  2N98 A;  4DG9 A;  2JB0 A;  1VQK P;  4GR6 A;  1Z6M A;  2FQ2 A;  2WPT A;  1VQN P;  1Q82 Q;  4F37 A;  2L22 A;  2QA4 P;  2GDW A;  3GKL C;  2K0D X;  3VRL C;  1RNI A;  2FAC A;  2M8N A;  3DS2 A;  1AF8 A;  3Q20 A;  3CCV P;  2CGQ A;  2KGD A;  1GXG A;  2PEK A;  2KG8 A;  4HKG A;  2GYK A;  3CD6 P;  2QNW A;  2EHT A;  1YIJ P;  3G21 A;  2KR5 A;  4XFZ A;  4XFY A;  2KOO A;  1JJ2 O;  2N6Y A;  4U0A A;  2AFE A;  2M8L A;  2LL8 A;  2XV6 A;  2KOP A;  1Q81 Q;  5BS1 A;  4PXH B;  5HV8 A;  5HVC A;  2GZI A;  2MY5 A;  1VQL P;  4PH0 A;  3G29 A;  2EG5 A;  2OAR A;  2CG5 B;  1BXI A;  1ZNV A;  2PEM A;  1W2B O;  4U0C A;  1F80 D;  3GJN A;  3RG2 A;  4GR2 A;  2GDY A;  2JYL A;  5F2K A;  2E1M A;  3P05 A;  1YHQ P;  2EFJ A;  3LMO A;  3G4S P;  2QEX P;  2MD9 A;  3DS0 A;  2OTJ P;  2PEJ A;  3G0V A;  4IPY A;  3GZL A;  3CCE P;  2N5H A;  2LML A;  2KGA A;  1YI2 P;  1M6N A;  2P9X A;  3G1G A;  4CA3 A;  3OW2 O;  2EIA A;  2JAZ A;  2LIU A;  2LOL A;  1QVF O;  2FQ1 A;  3EJB A;  1VHN A;  2ROQ A;  3I56 P;  1BAJ A;  1VQ5 P;  5EW5 E;  1VQ9 P;  3CPW O;  2GDX A;  1E6J P;  2PY8 A;  2JU1 A;  2MR8 A;  2FVE A;  1MZ8 A;  2ERH A;  1VQO P;  2XZ1 C;  2VLO A;  4M0I A;  2JU2 A;  1ZMB A;  4IZ6 A;  3DS5 A;  2LIW A;  3CE7 A;  2PEQ A;  3M1M A;  2N50 A;  4U0F A;  2GZE A;  1N8R Q;  2VLQ A;  1YIT P;  3CCU P;  2GZJ A;  3DTJ A;  2Z45 A;  4H2Y C;  3CCQ P;  3EJE A;  5JPA A;  3CC7 P;  2PNG A;  2L4B A;  2CQ8 A;  1KD1 Q;  2MF4 A;  2KG9 A;  5KP7 B;  2L6E A;  3E2D A;  5HGN A;  1L0H A;  3MGE A;  2VSQ A;  2GZF A;  4BPH A;  2FQ0 A;  4WYM A;  7CEI A;  2MVV A;  1DNY A;  1A8O A;  2FVF A;  3CME P;  3NTE A;  3CCJ P;  4XRO A;  2K93 A;  2N5I A;  1S72 P;  1YJ9 P;  1VKU A;  1NQ4 A;  4COP A;  5EJD A;  4BPF A;  4U0B A;  2DGY A;  4XRQ A;  1DV5 A;  2KGC A;  2CNR A;  3DS3 A;  2JYG A;  1VQP P;  3RG6 C;  4PWV B;  3H4E A;  4H2W C;  1K73 Q;  5HGL A;  1AYI A;  3HYB A;  4QNB A;  2AFD A;  2PEN A;  5F2N A;  2JBG A;  1AUM A;  4NEO A;  3B5I A;  3CCL P;  1NJI Q;  3CCM P;  3H0D A;  4U0D A;  3H47 A;  1YJW P;  2KOD A;  1K30 A;  4UHP B;  3DS1 A;  1IMQ A;  2KOR A;  2X2B A;  1CEI A;  1VQM P;  2FHS C;  4XFX A;  5I4T G;  2EHS A;  1QVG O;  4H2X C;  3G71 P;  2BUO A;  2KWL A;  2KW2 A;  1VQ8 P;  1Q7Y Q;  4BPG A;  5HGO A;  2K94 A;  2JO0 A;  1K9M Q;  5DCK A;  2KG6 A;  1GPJ A;  2K0X A;  1IUQ A;  3CMA P;  1KQS O;  3HZQ A;  2BHV A;  1FR2 A;  2XZ0 D;  5F2O A;  2Z46 A;  2K92 A;  2GZG A;  1RO2 A;  1A43 A;  2VLP A;  2AVA A;  5KP6 B;  3DPH A;  2ONT A;  1GXH A;  3WBH A;  1M90 Q;  1EMV A;  3U43 A;  1VQ6 P;  1UJZ A;  3CCR P;  3GZM A;  2XXM A;  3G26 A;  2LPK A;  3CC4 P;  1EOQ A;  2Z44 A;  2K5X A;  2AF8 A;  3EJD A;  2NO8 A;  1HQB A;  3I55 P;  3G6E P;  2L9F A;  1RO0 A;  2PEO A;  1UNK A;  3DS4 A;  2K0Y A;  3LRY A; 
#chains in the Genus database with same CATH homology
 2LIW A;  3CE7 A;  2N50 A;  1X3O A;  2KOR A;  5KP8 B;  2KR5 A;  2KOO A;  2X2B A;  2N6Y A;  2AFE A;  3NY7 B;  2LL8 A;  2FHS C;  2KOQ A;  2KOP A;  4H2Y C;  2EHS A;  3EJE A;  2JQ4 A;  4R0M A;  1L0I A;  4PXH B;  5HV8 A;  4H2X C;  5HVC A;  2M5R A;  2MY5 A;  1OR5 A;  2JGP A;  2KWL A;  2K2Q A;  2CG5 B;  2KW2 A;  2PNG A;  4BPG A;  2FAD A;  2L4B A;  2K94 A;  2CQ8 A;  4MRT C;  2MF4 A;  1ACP A;  2KG9 A;  5KP7 B;  2QNW A;  2KG6 A;  2K0X A;  2FVA A;  1F80 D;  2LKI A;  3RG2 A;  1L0H A;  2MR7 A;  2XZ0 D;  2GDY A;  1KLP A;  2KOS A;  2K92 A;  2FAE A;  2VSQ A;  2L0Q A;  4BPH A;  2KGE A;  2FQ0 A;  3LMO A;  2MVV A;  1DNY A;  2FVF A;  2K93 A;  2MD9 A;  1T8K A;  2LTE A;  2N5I A;  2AVA A;  5KP6 B;  2N6Z A;  1VKU A;  1NQ4 A;  3GZL A;  5CZD B;  2N5H A;  2LML A;  2KGA A;  5EJD A;  4BPF A;  1HY8 A;  2DNW A;  2MVU A;  2N98 A;  4CA3 A;  4DG9 A;  3GZM A;  1DV5 A;  2FQ2 A;  2LIU A;  2LOL A;  2KGC A;  2CNR A;  2FQ1 A;  2LPK A;  2L22 A;  3EJB A;  2GDW A;  2ROQ A;  4PWV B;  4H2W C;  2AF8 A;  2AFD A;  3EJD A;  2GDX A;  1HQB A;  2JU1 A;  2FAC A;  2MR8 A;  4NEO A;  1AF8 A;  2FVE A;  2CGQ A;  2L9F A;  2XZ1 C;  2KGD A;  2KG8 A;  4HKG A;  2JU2 A;  2K0Y A;  4IZ6 A;  2EHT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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