2L22A

Mupirocin didomain acp
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
183
structure length
183
Chain Sequence
VADDECAQFLRQSLAAMLYCEPGQIRDGSRFLELGLDSVIAAQWIREINKHYQLKIPADGIYTYPVFKAFTQWVGTQLQPTQATAAPVQREPVATAPQPGAQASAQRESIQDYLKQSLGELLFLDPGQLRSGAQFLDLGMDSVTGTQWMRGVSRHFSIQLAADAIYTWPTLKSLADEVDRRVQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A conserved motif flags acyl carrier proteins for beta-branching in polyketide synthesis.
pubmed doi rcsb
molecule tags Biosynthetic protein
source organism Pseudomonas fluorescens
molecule keywords Mupirocin didomain Acyl Carrier Protein
total genus 46
structure length 183
sequence length 183
ec nomenclature
pdb deposition date 2010-08-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 2l22A01
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 2l22A02
2KOQA 4NEOA 2LPKA 4R0MA 1F80D 1L0IA 2L9FA 3EJDA 2FAEA 2KG8A 2KWLA 2KGAA 2KR5A 2QNWA 3EJBA 2KOSA 2FADA 2DNWA 2KGDA 1NQ4A 2KGCA 4H2WC 2FVAA 2CGQA 1L0HA 2MY5A 2CG5B 2KW2A 3LMOA 2CQ8A 2K93A 3RG2A 2LIWA 2AVAA 2MD9A 2XZ1C 4BPGA 1HQBA 2LMLA 1DV5A 2PNGA 3EJEA 2N5IA 2KG9A 2AF8A 1DNYA 2LL8A 2JU1A 2N5HA 2X2BA 2EHTA 2GDYA 5KP8B 2MVUA 2N6ZA 2MR8A 2JGPA 5CZDB 2JQ4A 2L22A 2KG6A 2ROQA 4BPFA 2FHSC 1VKUA 2LKIA 2LIUA 2N50A 4DG9A 2GDWA 3NY7B 1X3OA 2EHSA 3CE7A 2KOPA 2FACA 2L0QA 5HVCA 2K0YA 2KORA 1OR5A 2LTEA 2CNRA 2AFDA 1T8KA 5KP7B 4HKGA 2LOLA 4H2XC 4CA3A 2K94A 4PWVB 2JU2A 2K0XA 2AFEA 4BPHA 2GDXA 2MVVA 2FVEA 1KLPA 3GZMA 3GZLA 2MR7A 5EJDA 4H2YC 4MRTC 2M5RA 1AF8A 2FVFA 5KP6B 2N6YA 2VSQA 1ACPA 5HV8A 2FQ0A 2K92A 2K2QA 2N98A 1HY8A 2XZ0D 2FQ1A 2L4BA 4PXHB 2KOOA 2KGEA 4IZ6A 2FQ2A 2MF4A
chains in the Genus database with same CATH superfamily
4U0EA 2LPKA 4R0MA 3EJDA 1VQMP 3WBHA 4WYMA 2EG5A 1M6EX 2VLNA 5HGNA 2DNWA 1NQ4A 4H2WC 3CCJP 2K5XA 2CGQA 1A43A 1VQ9P 2Z44A 2MY5A 3CXCO 2KW2A 2K93A 2E1MA 1Q81Q 5HGLA 4BPGA 1KC8Q 1GXGA 2LF4A 2PEMA 5F2NA 1D1DA 4PH0A 3CMEP 1HQBA 3G21A 2N5IA 3H4EA 3CCVP 2XV6A 2GZEA 2N5HA 1NJIQ 1YJWP 2MVUA 2JYGA 3CCEP 2JGPA 5CZDB 5DCKA 2JQ4A 2L22A 1ZNVA 2ROQA 1EMVA 1K73Q 2VLPA 2LIUA 2OTLP 3NY7B 1YJNP 2EHSA 2XXMA 3M1MA 1YJ9P 2K0YA 2DGYA 3CC4P 2P9XA 3MGEA 2LTEA 3G1GA 2CNRA 2NO8A 1VQ6P 4HKGA 2LOLA 4F37A 2M8NA 1RO0A 2K94A 2OTJP 4UHPB 4COCA 1KLPA 3GZMA 3GZLA 2M8LA 4XROA 4IPYA 4MRTC 5BS2A 4XFZA 1AF8A 2PENA 2PY8A 2FVFA 3G0VA 1ACPA 2K92A 1HY8A 2FQ1A 2KOOA 3NTEA 4IZ6A 1YIJP 4M0IA 2MF4A 4NEOA 2GZFA 1IMQA 1L0IA 2QEXP 2KG8A 2KWLA 2ERHA 3EJBA 4XFXA 2JO0A 2KGCA 2PEKA 2K0DX 2KODA 3LMOA 2MD9A 1FR2A 2LMLA 3DS5A 1QRJA 3H47A 2CWOA 1AUMA 2AF8A 2LL8A 1IMPA 2JU1A 3G71P 2VLQA 3DS4A 2JB0A 5F2KA 2EIAA 5KP8B 1VQNP 2MR8A 1KD1Q 1RO2A 1M6NA 4DG9A 5HVCA 5F2OA 2KORA 2GZIA 2AFDA 5KP7B 5HGMA 3CMAP 4H2XC 1VQ7P 3RG6C 2EFJA 4U0AA 4BPHA 3G28A 1QVGO 1VQ4P 1EIAA 4U0CA 1N8RQ 2GZGA 5I4TG 5HV8A 3CCSP 2FQ0A 1KQSO 2K2QA 2L4BA 4PXHB 1VHNA 2KGEA 3I55P 2FQ2A 1UJZA 2JAZA 3CC2P 1F80D 1IUQA 2FAEA 2KGAA 2OARA 2KR5A 2KOSA 2PEQA 3CD6P 2KGDA 3VRLC 2FVAA 3Q20A 1GPJA 1L0HA 3CPWO 1Q82Q 4U0BA 3CCRP 1BAJA 2AVAA 3P05A 1YHQP 1Z6MA 3DS1A 3CC7P 2L6EA 2PNGA 1K8AQ 2KG9A 1DNYA 1GXHA 3CCUP 2X2BA 2GDYA 2VLOA 3HYBA 3DTJA 1Q7YQ 4QNBA 2GYKA 3GKLC 2FHSC 2M8PA 2GDWA 1VQLP 1X3OA 3CE7A 2KOPA 2FACA 1OR5A 1MZ8A 1T8KA 4CA3A 4GR2A 3DS3A 4PWVB 2JU2A 2K0XA 1VQOP 2AFEA 2GDXA 4COPA 3G26A 2PEIA 1E6JP 3G29A 3CCQP 1EOQA 5BS1A 2Z45A 4H2YC 2BUOA 2N6YA 1JJ2O 1CEIA 1YI2P 2N98A 5JPAA 1VQPP 2PEJA 3LRYA 1M1KQ 2KOQA 2L9FA 4QKOA 2ONTA 1A8OA 1QVFO 1AYIA 2QNWA 1YITP 3CCMP 2FADA 2GZJA 1VQ5P 2CG5B 4XRQA 2CQ8A 3HZQA 3RG2A 2LIWA 2XZ1C 3E2DA 1DV5A 1K9MQ 3EJEA 3DPHA 2JBGA 3U43A 5EW5E 2EHTA 1W2BO 4XFYA 2PEOA 2N6ZA 1E0HA 7CEIA 2KG6A 4U0DA 4PH1A 4BPFA 1K30A 1S72P 1VKUA 2LKIA 2N50A 2L0QA 3G1IA 5HGOA 2XT1A 1VQKP 1M74A 3CCLP 2QA4P 1UNKA 2JYLA 2Z46A 2WPTA 3DS2A 1RNIA 3DS0A 3GJNA 2MVVA 2FVEA 3G4SP 3I56P 2MR7A 5EJDA 1Q86Q 2M5RA 1ZMBA 4GR6A 3B5IA 5KP6B 2VSQA 2BHVA 1BXIA 2XZ0D 3H0DA 3G6EP 4U0FA 1M90Q 1VQ8P 3B4QA 3OW2O
chains in the Genus database with same CATH topology
2KOQA 4NEOA 2LPKA 4R0MA 1F80D 1L0IA 2L9FA 3EJDA 2FAEA 2KG8A 2KWLA 2KGAA 2KR5A 2QNWA 3EJBA 2KOSA 2FADA 2DNWA 2KGDA 1NQ4A 2KGCA 4H2WC 2FVAA 2CGQA 1L0HA 2MY5A 2CG5B 2KW2A 3LMOA 2CQ8A 2K93A 3RG2A 2LIWA 2AVAA 2MD9A 2XZ1C 4BPGA 1HQBA 2LMLA 1DV5A 2PNGA 3EJEA 2N5IA 2KG9A 2AF8A 1DNYA 2LL8A 2JU1A 2N5HA 2X2BA 2EHTA 2GDYA 5KP8B 2MVUA 2N6ZA 2MR8A 2JGPA 5CZDB 2JQ4A 2L22A 2KG6A 2ROQA 4BPFA 2FHSC 1VKUA 2LKIA 2LIUA 2N50A 4DG9A 2GDWA 3NY7B 1X3OA 2EHSA 3CE7A 2KOPA 2FACA 2L0QA 5HVCA 2K0YA 2KORA 1OR5A 2LTEA 2CNRA 2AFDA 1T8KA 5KP7B 4HKGA 2LOLA 4H2XC 4CA3A 2K94A 4PWVB 2JU2A 2K0XA 2AFEA 4BPHA 2GDXA 2MVVA 2FVEA 1KLPA 3GZMA 3GZLA 2MR7A 5EJDA 4H2YC 4MRTC 2M5RA 1AF8A 2FVFA 5KP6B 2N6YA 2VSQA 1ACPA 5HV8A 2FQ0A 2K92A 2K2QA 2N98A 1HY8A 2XZ0D 2FQ1A 2L4BA 4PXHB 2KOOA 2KGEA 4IZ6A 2FQ2A 2MF4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KOQ A;  4NEO A;  2LPK A;  4R0M A;  1F80 D;  1L0I A;  2L9F A;  3EJD A;  2FAE A;  2KG8 A;  2KWL A;  2KGA A;  2KR5 A;  2QNW A;  3EJB A;  2KOS A;  2FAD A;  2DNW A;  2KGD A;  1NQ4 A;  2KGC A;  4H2W C;  2FVA A;  2CGQ A;  1L0H A;  2MY5 A;  2CG5 B;  2KW2 A;  3LMO A;  2CQ8 A;  2K93 A;  3RG2 A;  2LIW A;  2AVA A;  2MD9 A;  2XZ1 C;  4BPG A;  1HQB A;  2LML A;  1DV5 A;  2PNG A;  3EJE A;  2N5I A;  2KG9 A;  2AF8 A;  1DNY A;  2LL8 A;  2JU1 A;  2N5H A;  2X2B A;  2EHT A;  2GDY A;  5KP8 B;  2MVU A;  2N6Z A;  2MR8 A;  2JGP A;  5CZD B;  2JQ4 A;  2L22 A;  2KG6 A;  2ROQ A;  4BPF A;  2FHS C;  1VKU A;  2LKI A;  2LIU A;  2N50 A;  4DG9 A;  2GDW A;  3NY7 B;  1X3O A;  2EHS A;  3CE7 A;  2KOP A;  2FAC A;  2L0Q A;  5HVC A;  2K0Y A;  2KOR A;  1OR5 A;  2LTE A;  2CNR A;  2AFD A;  1T8K A;  5KP7 B;  4HKG A;  2LOL A;  4H2X C;  4CA3 A;  2K94 A;  4PWV B;  2JU2 A;  2K0X A;  2AFE A;  4BPH A;  2GDX A;  2MVV A;  2FVE A;  1KLP A;  3GZM A;  3GZL A;  2MR7 A;  5EJD A;  4H2Y C;  4MRT C;  2M5R A;  1AF8 A;  2FVF A;  5KP6 B;  2N6Y A;  2VSQ A;  1ACP A;  5HV8 A;  2FQ0 A;  2K92 A;  2K2Q A;  2N98 A;  1HY8 A;  2XZ0 D;  2FQ1 A;  2L4B A;  4PXH B;  2KOO A;  2KGE A;  4IZ6 A;  2FQ2 A;  2MF4 A; 
#chains in the Genus database with same CATH topology
 4U0E A;  2LPK A;  4R0M A;  3EJD A;  1VQM P;  3WBH A;  4WYM A;  2EG5 A;  1M6E X;  2VLN A;  5HGN A;  2DNW A;  1NQ4 A;  4H2W C;  3CCJ P;  2K5X A;  2CGQ A;  1A43 A;  1VQ9 P;  2Z44 A;  2MY5 A;  3CXC O;  2KW2 A;  2K93 A;  2E1M A;  1Q81 Q;  5HGL A;  4BPG A;  1KC8 Q;  1GXG A;  2LF4 A;  2PEM A;  5F2N A;  1D1D A;  4PH0 A;  3CME P;  1HQB A;  3G21 A;  2N5I A;  3H4E A;  3CCV P;  2XV6 A;  2GZE A;  2N5H A;  1NJI Q;  1YJW P;  2MVU A;  2JYG A;  3CCE P;  2JGP A;  5CZD B;  5DCK A;  2JQ4 A;  2L22 A;  1ZNV A;  2ROQ A;  1EMV A;  1K73 Q;  2VLP A;  2LIU A;  2OTL P;  3NY7 B;  1YJN P;  2EHS A;  2XXM A;  3M1M A;  1YJ9 P;  2K0Y A;  2DGY A;  3CC4 P;  2P9X A;  3MGE A;  2LTE A;  3G1G A;  2CNR A;  2NO8 A;  1VQ6 P;  4HKG A;  2LOL A;  4F37 A;  2M8N A;  1RO0 A;  2K94 A;  2OTJ P;  4UHP B;  4COC A;  1KLP A;  3GZM A;  3GZL A;  2M8L A;  4XRO A;  4IPY A;  4MRT C;  5BS2 A;  4XFZ A;  1AF8 A;  2PEN A;  2PY8 A;  2FVF A;  3G0V A;  1ACP A;  2K92 A;  1HY8 A;  2FQ1 A;  2KOO A;  3NTE A;  4IZ6 A;  1YIJ P;  4M0I A;  2MF4 A;  4NEO A;  2GZF A;  1IMQ A;  1L0I A;  2QEX P;  2KG8 A;  2KWL A;  2ERH A;  3EJB A;  4XFX A;  2JO0 A;  2KGC A;  2PEK A;  2K0D X;  2KOD A;  3LMO A;  2MD9 A;  1FR2 A;  2LML A;  3DS5 A;  1QRJ A;  3H47 A;  2CWO A;  1AUM A;  2AF8 A;  2LL8 A;  1IMP A;  2JU1 A;  3G71 P;  2VLQ A;  3DS4 A;  2JB0 A;  5F2K A;  2EIA A;  5KP8 B;  1VQN P;  2MR8 A;  1KD1 Q;  1RO2 A;  1M6N A;  4DG9 A;  5HVC A;  5F2O A;  2KOR A;  2GZI A;  2AFD A;  5KP7 B;  5HGM A;  3CMA P;  4H2X C;  1VQ7 P;  3RG6 C;  2EFJ A;  4U0A A;  4BPH A;  3G28 A;  1QVG O;  1VQ4 P;  1EIA A;  4U0C A;  1N8R Q;  2GZG A;  5I4T G;  5HV8 A;  3CCS P;  2FQ0 A;  1KQS O;  2K2Q A;  2L4B A;  4PXH B;  1VHN A;  2KGE A;  3I55 P;  2FQ2 A;  1UJZ A;  2JAZ A;  3CC2 P;  1F80 D;  1IUQ A;  2FAE A;  2KGA A;  2OAR A;  2KR5 A;  2KOS A;  2PEQ A;  3CD6 P;  2KGD A;  3VRL C;  2FVA A;  3Q20 A;  1GPJ A;  1L0H A;  3CPW O;  1Q82 Q;  4U0B A;  3CCR P;  1BAJ A;  2AVA A;  3P05 A;  1YHQ P;  1Z6M A;  3DS1 A;  3CC7 P;  2L6E A;  2PNG A;  1K8A Q;  2KG9 A;  1DNY A;  1GXH A;  3CCU P;  2X2B A;  2GDY A;  2VLO A;  3HYB A;  3DTJ A;  1Q7Y Q;  4QNB A;  2GYK A;  3GKL C;  2FHS C;  2M8P A;  2GDW A;  1VQL P;  1X3O A;  3CE7 A;  2KOP A;  2FAC A;  1OR5 A;  1MZ8 A;  1T8K A;  4CA3 A;  4GR2 A;  3DS3 A;  4PWV B;  2JU2 A;  2K0X A;  1VQO P;  2AFE A;  2GDX A;  4COP A;  3G26 A;  2PEI A;  1E6J P;  3G29 A;  3CCQ P;  1EOQ A;  5BS1 A;  2Z45 A;  4H2Y C;  2BUO A;  2N6Y A;  1JJ2 O;  1CEI A;  1YI2 P;  2N98 A;  5JPA A;  1VQP P;  2PEJ A;  3LRY A;  1M1K Q;  2KOQ A;  2L9F A;  4QKO A;  2ONT A;  1A8O A;  1QVF O;  1AYI A;  2QNW A;  1YIT P;  3CCM P;  2FAD A;  2GZJ A;  1VQ5 P;  2CG5 B;  4XRQ A;  2CQ8 A;  3HZQ A;  3RG2 A;  2LIW A;  2XZ1 C;  3E2D A;  1DV5 A;  1K9M Q;  3EJE A;  3DPH A;  2JBG A;  3U43 A;  5EW5 E;  2EHT A;  1W2B O;  4XFY A;  2PEO A;  2N6Z A;  1E0H A;  7CEI A;  2KG6 A;  4U0D A;  4PH1 A;  4BPF A;  1K30 A;  1S72 P;  1VKU A;  2LKI A;  2N50 A;  2L0Q A;  3G1I A;  5HGO A;  2XT1 A;  1VQK P;  1M74 A;  3CCL P;  2QA4 P;  1UNK A;  2JYL A;  2Z46 A;  2WPT A;  3DS2 A;  1RNI A;  3DS0 A;  3GJN A;  2MVV A;  2FVE A;  3G4S P;  3I56 P;  2MR7 A;  5EJD A;  1Q86 Q;  2M5R A;  1ZMB A;  4GR6 A;  3B5I A;  5KP6 B;  2VSQ A;  2BHV A;  1BXI A;  2XZ0 D;  3H0D A;  3G6E P;  4U0F A;  1M90 Q;  1VQ8 P;  3B4Q A;  3OW2 O; 
#chains in the Genus database with same CATH homology
 2KOQ A;  4NEO A;  2LPK A;  4R0M A;  1F80 D;  1L0I A;  2L9F A;  3EJD A;  2FAE A;  2KG8 A;  2KWL A;  2KGA A;  2KR5 A;  2QNW A;  3EJB A;  2KOS A;  2FAD A;  2DNW A;  2KGD A;  1NQ4 A;  2KGC A;  4H2W C;  2FVA A;  2CGQ A;  1L0H A;  2MY5 A;  2CG5 B;  2KW2 A;  3LMO A;  2CQ8 A;  2K93 A;  3RG2 A;  2LIW A;  2AVA A;  2MD9 A;  2XZ1 C;  4BPG A;  1HQB A;  2LML A;  1DV5 A;  2PNG A;  3EJE A;  2N5I A;  2KG9 A;  2AF8 A;  1DNY A;  2LL8 A;  2JU1 A;  2N5H A;  2X2B A;  2EHT A;  2GDY A;  5KP8 B;  2MVU A;  2N6Z A;  2MR8 A;  2JGP A;  5CZD B;  2JQ4 A;  2L22 A;  2KG6 A;  2ROQ A;  4BPF A;  2FHS C;  1VKU A;  2LKI A;  2LIU A;  2N50 A;  4DG9 A;  2GDW A;  3NY7 B;  1X3O A;  2EHS A;  3CE7 A;  2KOP A;  2FAC A;  2L0Q A;  5HVC A;  2K0Y A;  2KOR A;  1OR5 A;  2LTE A;  2CNR A;  2AFD A;  1T8K A;  5KP7 B;  4HKG A;  2LOL A;  4H2X C;  4CA3 A;  2K94 A;  4PWV B;  2JU2 A;  2K0X A;  2AFE A;  4BPH A;  2GDX A;  2MVV A;  2FVE A;  1KLP A;  3GZM A;  3GZL A;  2MR7 A;  5EJD A;  4H2Y C;  4MRT C;  2M5R A;  1AF8 A;  2FVF A;  5KP6 B;  2N6Y A;  2VSQ A;  1ACP A;  5HV8 A;  2FQ0 A;  2K92 A;  2K2Q A;  2N98 A;  1HY8 A;  2XZ0 D;  2FQ1 A;  2L4B A;  4PXH B;  2KOO A;  2KGE A;  4IZ6 A;  2FQ2 A;  2MF4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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