2XV6A

Crystal structure of the hiv-1 capsid protein c-terminal domain (146- 220) in complex with a camelid vhh.
Total Genus 28
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
75
structure length
75
Chain Sequence
SPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPGATLEEMMTACQG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Targeting HIV-1 Virion Formation with Nanobodies -Implications for the Design of Assembly Inhibitors
rcsb
molecule tags Viral protein/immune system
source organism Human immunodeficiency virus 1
molecule keywords CAPSID PROTEIN P24
total genus 28
structure length 75
sequence length 75
chains with identical sequence C
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2010-10-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.30 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A 2xv6A00
3DS4A 4PH1A 4COPA 4PH0A 4U0CA 3G26A 3VRLC 5DCKA 2M8LA 4U0AA 3G0VA 3G29A 4IPYA 4WYMA 4COCA 3P05A 2JO0A 2KODA 3DS1A 3DTJA 4QNBA 3NTEA 4M0IA 3H47A 4U0EA 2JYGA 3G28A 3DS0A 4U0DA 5HGLA 3LRYA 1EIAA 4U0BA 3G21A 2JYLA 1EOQA 1QRJA 2ONTA 2BUOA 4XFXA 5HGNA 1BAJA 1A8OA 5HGMA 5I4TG 1D1DA 4XROA 4XFYA 2M8NA 2M8PA 3DS2A 3G1GA 2XV6A 3DS3A 4U0FA 5JPAA 3DPHA 1E6JP 2XXMA 3H4EA 3DS5A 4XRQA 2L6EA 5HGOA 3G1IA 2LF4A 2XT1A 1A43A 3MGEA 2EIAA 4XFZA 1AUMA
chains in the Genus database with same CATH superfamily
2JB0A 2NO8A 5EW5E 2VLNA 4WYMA 4COCA 2K94A 3M1MA 5KP7B 4U0DA 3I55P 2MR7A 1AYIA 5EJDA 4U0FA 3DS3A 3DPHA 4GR2A 1BXIA 2FQ1A 2VSQA 3CMAP 1DV5A 2QEXP 2Z44A 2FADA 2P9XA 5DCKA 1JJ2O 2X2BA 1VQKP 2QA4P 3P05A 3CCUP 4M0IA 1M90Q 2JYGA 3CCVP 1DNYA 1EMVA 3H4EA 3HZQA 2K0YA 3GZMA 3Q20A 2VLOA 1Q86Q 3CCSP 1QVGO 3DS4A 4COPA 2KOOA 3G29A 2PEMA 4QNBA 2EHSA 1RO2A 4HKGA 5HGNA 3I56P 1T8KA 1S72P 1ACPA 2GZJA 3RG2A 2N5HA 2MVVA 2CG5B 4PH1A 2FVEA 2M8LA 3G0VA 2ROQA 5HVCA 3CXCO 2K93A 2LTEA 3LRYA 3EJBA 2BUOA 1Z6MA 2LOLA 5I4TG 5KP6B 1CEIA 2XZ1C 1VQ5P 2K0XA 2N5IA 2L4BA 3NTEA 1E0HA 1AUMA 2KORA 2KGDA 1VQ4P 2AVAA 3G21A 1KC8Q 2JU1A 2EG5A 5HGMA 1YIJP 2FAEA 5JPAA 3GJNA 7CEIA 2KR5A 2L22A 3G1IA 1GPJA 2MR8A 1VQ7P 1VKUA 1MZ8A 2GZFA 2KOPA 1NJIQ 2JO0A 2OTLP 2ONTA 2LKIA 1OR5A 5F2NA 4UHPB 2LL8A 3CC7P 3OW2O 2XV6A 2PEKA 1UNKA 2N6ZA 2PEJA 1VQLP 5BS2A 2OARA 1Q7YQ 1K9MQ 1VQ9P 1KQSO 3E2DA 1NQ4A 1AF8A 2N98A 2N50A 2KGCA 2MVUA 2MD9A 2AF8A 1M6EX 4BPFA 4XFYA 1VQOP 3DS2A 4QKOA 1QVFO 2DNWA 2GDWA 1Q81Q 3G4SP 2L0QA 3CMEP 2CGQA 2VLQA 2GYKA 3H47A 1VHNA 3U43A 2KW2A 1RNIA 2CQ8A 3GZLA 2KOQA 4BPGA 2ERHA 3H0DA 3CCLP 1YHQP 3NY7B 4IPYA 3DTJA 5HGLA 2FHSC 1QRJA 2KG9A 1VQMP 2VLPA 2FVAA 4PWVB 3DS5A 1YITP 1UJZA 1X3OA 1K73Q 2PEQA 2JQ4A 2EIAA 4XFZA 4IZ6A 2DGYA 2FQ0A 1HQBA 3LMOA 3G26A 3GKLC 2GZEA 3CE7A 2GZIA 2KODA 3DS0A 2AFDA 2GDXA 3CCJP 2KOSA 1VQNP 3RG6C 3CPWO 1BAJA 2CNRA 2M8NA 2XZ0D 1VQ6P 3CC2P 1VQPP 2JBGA 1YJNP 4NEOA 2FACA 1Q82Q 3HYBA 1YJWP 2PEIA 4U0EA 2CWOA 1EOQA 5HV8A 3CCEP 2E1MA 4MRTC 1KLPA 2KGEA 4XRQA 1F80D 1W2BO 3G71P 2XT1A 1IUQA 5CZDB 2K5XA 2PNGA 4F37A 2KG6A 5BS1A 4U0CA 2PENA 1GXGA 2EFJA 2JAZA 1K30A 1L0IA 3CC4P 3CCQP 1M1KQ 1FR2A 2LPKA 1YJ9P 3CD6P 3CCRP 3EJDA 1A8OA 1KD1Q 3VRLC 2LIUA 2KGAA 1ZNVA 3WBHA 2PY8A 1M6NA 2Z45A 2KG8A 3B4QA 1M74A 3B5IA 2L6EA 4CA3A 2GZGA 2JU2A 3EJEA 2XXMA 1IMPA 2Z46A 1GXHA 3CCMP 2FVFA 1VQ8P 2K0DX 2LMLA 2JYLA 1K8AQ 1ZMBA 2JGPA 1YI2P 2K2QA 4R0MA 2KWLA 5HGOA 2FQ2A 2LIWA 1D1DA 2K92A 2PEOA 4PH0A 3G6EP 4U0AA 2N6YA 3DS1A 2QNWA 2M5RA 3G28A 1EIAA 4DG9A 4XFXA 4H2WC 5F2KA 4PXHB 2OTJP 1L0HA 1E6JP 4GR6A 2BHVA 1IMQA 2MF4A 2LF4A 2WPTA 4H2XC 2MY5A 2L9FA 2EHTA 4BPHA 5F2OA 4U0BA 2AFEA 4XROA 5KP8B 2M8PA 3G1GA 4H2YC 1N8RQ 1RO0A 1HY8A 2GDYA 1A43A 3MGEA
chains in the Genus database with same CATH topology
1YHQP 3VRLC 4IPYA 4WYMA 4COCA 3DTJA 3M1MA 1VQ4P 5HGLA 4U0DA 3WBHA 3G21A 1KC8Q 1QRJA 3I55P 2EG5A 1VQMP 2PY8A 1M6NA 5HGMA 1YIJP 2Z45A 4U0FA 1A43A 3DS3A 5JPAA 3DPHA 4GR2A 3DS5A 1M74A 3B5IA 2L6EA 1YITP 3G1IA 3CMAP 1K73Q 2QEXP 2PEQA 1VQ7P 2XXMA 2EIAA 4XFZA 2Z44A 2DGYA 2Z46A 2P9XA 3G26A 5DCKA 1JJ2O 1VQKP 2QA4P 3CCMP 3P05A 2JO0A 1NJIQ 2KODA 3CCUP 4M0IA 1M90Q 2JYGA 1VQ8P 3DS0A 3CCVP 2OTLP 3CCJP 2JYLA 2ONTA 1K8AQ 1VQNP 3RG6C 5F2NA 3CPWO 1BAJA 1ZMBA 1A8OA 3CC7P 2M8NA 1YI2P 3OW2O 2XV6A 2PEKA 3H4EA 3HZQA 2PEJA 1VQ6P 3CC2P 1VQLP 5BS2A 2OARA 5HGOA 1VQPP 1Q7YQ 1K9MQ 3Q20A 1VQ9P 1YJNP 1D1DA 1Q86Q 3CCSP 1KQSO 1QVGO 3DS4A 1Q82Q 4COPA 2PEOA 4PH0A 3HYBA 1YJWP 3G6EP 3E2DA 4U0AA 3G29A 2PEIA 3DS1A 2PEMA 4QNBA 4U0EA 2CWOA 3G28A 1EIAA 4XFXA 1EOQA 3CCEP 1RO2A 2E1MA 5F2KA 5HGNA 1M6EX 2OTJP 4XFYA 3I56P 1VQOP 3DS2A 1E6JP 4GR6A 4XRQA 2BHVA 1S72P 1QVFO 1W2BO 3G4SP 1Q81Q 2LF4A 3G71P 2XT1A 1IUQA 3CMEP 4PH1A 5BS1A 4U0CA 2PENA 2M8LA 3G0VA 2EFJA 5F2OA 1K30A 3CXCO 3H47A 3LRYA 4U0BA 3CC4P 1RNIA 2BUOA 3CCQP 5I4TG 4XROA 2M8PA 3G1GA 1M1KQ 1YJ9P 1VQ5P 3CD6P 1N8RQ 1RO0A 3H0DA 3CCRP 3NTEA 3CCLP 3MGEA 1KD1Q 1AUMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DS4 A;  4PH1 A;  4COP A;  4PH0 A;  4U0C A;  3G26 A;  3VRL C;  5DCK A;  2M8L A;  4U0A A;  3G0V A;  3G29 A;  4IPY A;  4WYM A;  4COC A;  3P05 A;  2JO0 A;  2KOD A;  3DS1 A;  3DTJ A;  4QNB A;  3NTE A;  4M0I A;  3H47 A;  4U0E A;  2JYG A;  3G28 A;  3DS0 A;  4U0D A;  5HGL A;  3LRY A;  1EIA A;  4U0B A;  3G21 A;  2JYL A;  1EOQ A;  1QRJ A;  2ONT A;  2BUO A;  4XFX A;  5HGN A;  1BAJ A;  1A8O A;  5HGM A;  5I4T G;  1D1D A;  4XRO A;  4XFY A;  2M8N A;  2M8P A;  3DS2 A;  3G1G A;  2XV6 A;  3DS3 A;  4U0F A;  5JPA A;  3DPH A;  1E6J P;  2XXM A;  3H4E A;  3DS5 A;  4XRQ A;  2L6E A;  5HGO A;  3G1I A;  2LF4 A;  2XT1 A;  1A43 A;  3MGE A;  2EIA A;  4XFZ A;  1AUM A; 
#chains in the Genus database with same CATH topology
 2JB0 A;  2NO8 A;  5EW5 E;  2VLN A;  4WYM A;  4COC A;  2K94 A;  3M1M A;  5KP7 B;  4U0D A;  3I55 P;  2MR7 A;  1AYI A;  5EJD A;  4U0F A;  3DS3 A;  3DPH A;  4GR2 A;  1BXI A;  2FQ1 A;  2VSQ A;  3CMA P;  1DV5 A;  2QEX P;  2Z44 A;  2FAD A;  2P9X A;  5DCK A;  1JJ2 O;  2X2B A;  1VQK P;  2QA4 P;  3P05 A;  3CCU P;  4M0I A;  1M90 Q;  2JYG A;  3CCV P;  1DNY A;  1EMV A;  3H4E A;  3HZQ A;  2K0Y A;  3GZM A;  3Q20 A;  2VLO A;  1Q86 Q;  3CCS P;  1QVG O;  3DS4 A;  4COP A;  2KOO A;  3G29 A;  2PEM A;  4QNB A;  2EHS A;  1RO2 A;  4HKG A;  5HGN A;  3I56 P;  1T8K A;  1S72 P;  1ACP A;  2GZJ A;  3RG2 A;  2N5H A;  2MVV A;  2CG5 B;  4PH1 A;  2FVE A;  2M8L A;  3G0V A;  2ROQ A;  5HVC A;  3CXC O;  2K93 A;  2LTE A;  3LRY A;  3EJB A;  2BUO A;  1Z6M A;  2LOL A;  5I4T G;  5KP6 B;  1CEI A;  2XZ1 C;  1VQ5 P;  2K0X A;  2N5I A;  2L4B A;  3NTE A;  1E0H A;  1AUM A;  2KOR A;  2KGD A;  1VQ4 P;  2AVA A;  3G21 A;  1KC8 Q;  2JU1 A;  2EG5 A;  5HGM A;  1YIJ P;  2FAE A;  5JPA A;  3GJN A;  7CEI A;  2KR5 A;  2L22 A;  3G1I A;  1GPJ A;  2MR8 A;  1VQ7 P;  1VKU A;  1MZ8 A;  2GZF A;  2KOP A;  1NJI Q;  2JO0 A;  2OTL P;  2ONT A;  2LKI A;  1OR5 A;  5F2N A;  4UHP B;  2LL8 A;  3CC7 P;  3OW2 O;  2XV6 A;  2PEK A;  1UNK A;  2N6Z A;  2PEJ A;  1VQL P;  5BS2 A;  2OAR A;  1Q7Y Q;  1K9M Q;  1VQ9 P;  1KQS O;  3E2D A;  1NQ4 A;  1AF8 A;  2N98 A;  2N50 A;  2KGC A;  2MVU A;  2MD9 A;  2AF8 A;  1M6E X;  4BPF A;  4XFY A;  1VQO P;  3DS2 A;  4QKO A;  1QVF O;  2DNW A;  2GDW A;  1Q81 Q;  3G4S P;  2L0Q A;  3CME P;  2CGQ A;  2VLQ A;  2GYK A;  3H47 A;  1VHN A;  3U43 A;  2KW2 A;  1RNI A;  2CQ8 A;  3GZL A;  2KOQ A;  4BPG A;  2ERH A;  3H0D A;  3CCL P;  1YHQ P;  3NY7 B;  4IPY A;  3DTJ A;  5HGL A;  2FHS C;  1QRJ A;  2KG9 A;  1VQM P;  2VLP A;  2FVA A;  4PWV B;  3DS5 A;  1YIT P;  1UJZ A;  1X3O A;  1K73 Q;  2PEQ A;  2JQ4 A;  2EIA A;  4XFZ A;  4IZ6 A;  2DGY A;  2FQ0 A;  1HQB A;  3LMO A;  3G26 A;  3GKL C;  2GZE A;  3CE7 A;  2GZI A;  2KOD A;  3DS0 A;  2AFD A;  2GDX A;  3CCJ P;  2KOS A;  1VQN P;  3RG6 C;  3CPW O;  1BAJ A;  2CNR A;  2M8N A;  2XZ0 D;  1VQ6 P;  3CC2 P;  1VQP P;  2JBG A;  1YJN P;  4NEO A;  2FAC A;  1Q82 Q;  3HYB A;  1YJW P;  2PEI A;  4U0E A;  2CWO A;  1EOQ A;  5HV8 A;  3CCE P;  2E1M A;  4MRT C;  1KLP A;  2KGE A;  4XRQ A;  1F80 D;  1W2B O;  3G71 P;  2XT1 A;  1IUQ A;  5CZD B;  2K5X A;  2PNG A;  4F37 A;  2KG6 A;  5BS1 A;  4U0C A;  2PEN A;  1GXG A;  2EFJ A;  2JAZ A;  1K30 A;  1L0I A;  3CC4 P;  3CCQ P;  1M1K Q;  1FR2 A;  2LPK A;  1YJ9 P;  3CD6 P;  3CCR P;  3EJD A;  1A8O A;  1KD1 Q;  3VRL C;  2LIU A;  2KGA A;  1ZNV A;  3WBH A;  2PY8 A;  1M6N A;  2Z45 A;  2KG8 A;  3B4Q A;  1M74 A;  3B5I A;  2L6E A;  4CA3 A;  2GZG A;  2JU2 A;  3EJE A;  2XXM A;  1IMP A;  2Z46 A;  1GXH A;  3CCM P;  2FVF A;  1VQ8 P;  2K0D X;  2LML A;  2JYL A;  1K8A Q;  1ZMB A;  2JGP A;  1YI2 P;  2K2Q A;  4R0M A;  2KWL A;  5HGO A;  2FQ2 A;  2LIW A;  1D1D A;  2K92 A;  2PEO A;  4PH0 A;  3G6E P;  4U0A A;  2N6Y A;  3DS1 A;  2QNW A;  2M5R A;  3G28 A;  1EIA A;  4DG9 A;  4XFX A;  4H2W C;  5F2K A;  4PXH B;  2OTJ P;  1L0H A;  1E6J P;  4GR6 A;  2BHV A;  1IMQ A;  2MF4 A;  2LF4 A;  2WPT A;  4H2X C;  2MY5 A;  2L9F A;  2EHT A;  4BPH A;  5F2O A;  4U0B A;  2AFE A;  4XRO A;  5KP8 B;  2M8P A;  3G1G A;  4H2Y C;  1N8R Q;  1RO0 A;  1HY8 A;  2GDY A;  1A43 A;  3MGE A; 
#chains in the Genus database with same CATH homology
 1YHQ P;  3VRL C;  4IPY A;  4WYM A;  4COC A;  3DTJ A;  3M1M A;  1VQ4 P;  5HGL A;  4U0D A;  3WBH A;  3G21 A;  1KC8 Q;  1QRJ A;  3I55 P;  2EG5 A;  1VQM P;  2PY8 A;  1M6N A;  5HGM A;  1YIJ P;  2Z45 A;  4U0F A;  1A43 A;  3DS3 A;  5JPA A;  3DPH A;  4GR2 A;  3DS5 A;  1M74 A;  3B5I A;  2L6E A;  1YIT P;  3G1I A;  3CMA P;  1K73 Q;  2QEX P;  2PEQ A;  1VQ7 P;  2XXM A;  2EIA A;  4XFZ A;  2Z44 A;  2DGY A;  2Z46 A;  2P9X A;  3G26 A;  5DCK A;  1JJ2 O;  1VQK P;  2QA4 P;  3CCM P;  3P05 A;  2JO0 A;  1NJI Q;  2KOD A;  3CCU P;  4M0I A;  1M90 Q;  2JYG A;  1VQ8 P;  3DS0 A;  3CCV P;  2OTL P;  3CCJ P;  2JYL A;  2ONT A;  1K8A Q;  1VQN P;  3RG6 C;  5F2N A;  3CPW O;  1BAJ A;  1ZMB A;  1A8O A;  3CC7 P;  2M8N A;  1YI2 P;  3OW2 O;  2XV6 A;  2PEK A;  3H4E A;  3HZQ A;  2PEJ A;  1VQ6 P;  3CC2 P;  1VQL P;  5BS2 A;  2OAR A;  5HGO A;  1VQP P;  1Q7Y Q;  1K9M Q;  3Q20 A;  1VQ9 P;  1YJN P;  1D1D A;  1Q86 Q;  3CCS P;  1KQS O;  1QVG O;  3DS4 A;  1Q82 Q;  4COP A;  2PEO A;  4PH0 A;  3HYB A;  1YJW P;  3G6E P;  3E2D A;  4U0A A;  3G29 A;  2PEI A;  3DS1 A;  2PEM A;  4QNB A;  4U0E A;  2CWO A;  3G28 A;  1EIA A;  4XFX A;  1EOQ A;  3CCE P;  1RO2 A;  2E1M A;  5F2K A;  5HGN A;  1M6E X;  2OTJ P;  4XFY A;  3I56 P;  1VQO P;  3DS2 A;  1E6J P;  4GR6 A;  4XRQ A;  2BHV A;  1S72 P;  1QVF O;  1W2B O;  3G4S P;  1Q81 Q;  2LF4 A;  3G71 P;  2XT1 A;  1IUQ A;  3CME P;  4PH1 A;  5BS1 A;  4U0C A;  2PEN A;  2M8L A;  3G0V A;  2EFJ A;  5F2O A;  1K30 A;  3CXC O;  3H47 A;  3LRY A;  4U0B A;  3CC4 P;  1RNI A;  2BUO A;  3CCQ P;  5I4T G;  4XRO A;  2M8P A;  3G1G A;  1M1K Q;  1YJ9 P;  1VQ5 P;  3CD6 P;  1N8R Q;  1RO0 A;  3H0D A;  3CCR P;  3NTE A;  3CCL P;  3MGE A;  1KD1 Q;  1AUM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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