3DS1A

Hiv-1 capsid c-terminal domain mutant (e187a) in complex with an inhibitor of particle assembly (cai)
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
81
structure length
81
Chain Sequence
TSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTATLLVQNANPDCKTILKALGPGATLEEMMTACQGVGGPGHKA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein.
pubmed doi rcsb
molecule tags Viral protein
source organism Human immunodeficiency virus 1
molecule keywords HIV-1 CAPSID PROTEIN
total genus 29
structure length 81
sequence length 81
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2008-07-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.30 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A 3ds1A00
3P05A 4M0IA 1AUMA 4U0AA 3DS5A 3G1GA 3H4EA 3DS3A 4U0CA 4XFZA 4PH0A 1D1DA 2L6EA 1EOQA 1EIAA 5HGLA 2M8PA 3DS0A 3G0VA 3MGEA 4U0BA 2M8NA 2M8LA 4XRQA 4PH1A 3DS4A 5HGMA 2ONTA 3H47A 4XFYA 4U0FA 3LRYA 5HGOA 2EIAA 3DS2A 4COPA 3NTEA 4COCA 2XXMA 5I4TG 2KODA 3VRLC 1QRJA 2XT1A 3DPHA 4IPYA 5JPAA 3G28A 1E6JP 4QNBA 3G29A 3G26A 2JYLA 2LF4A 4U0EA 4U0DA 4XROA 2BUOA 2XV6A 4XFXA 2JYGA 5DCKA 2JO0A 5HGNA 1A8OA 3DTJA 1BAJA 3DS1A 3G1IA 4WYMA 3G21A 1A43A
chains in the Genus database with same CATH superfamily
4UHPB 3H4EA 1AF8A 3CCLP 2L9FA 2PEQA 2M8PA 2PEJA 1KD1Q 5CZDB 5BS1A 2PEKA 1YHQP 3G28A 2FQ0A 2GZIA 2CG5B 1GPJA 2LPKA 1HQBA 3G1GA 1YJ9P 2KW2A 7CEIA 2L4BA 3CE7A 4MRTC 4GR6A 2FQ2A 2N5IA 2GZJA 2FVAA 4PWVB 2VLQA 4IPYA 3LMOA 2LTEA 2AFDA 4GR2A 5DCKA 1L0HA 3CCJP 2PEOA 2CGQA 1GXHA 3CXCO 2P9XA 1D1DA 1RNIA 2EHTA 2LIUA 3H47A 4HKGA 1UJZA 3U43A 3CCEP 1RO0A 2FAEA 4NEOA 5I4TG 2KODA 3CC2P 1M74A 1UNKA 2LF4A 3H0DA 2JU2A 2XZ1C 2JO0A 1T8KA 2N98A 2M5RA 2MVUA 3P05A 3Q20A 2K0XA 2GDXA 2N6ZA 3DS3A 4PH0A 5F2KA 2N6YA 2M8LA 2FHSC 3CCRP 4BPHA 3EJDA 2EG5A 1OR5A 3OW2O 2KG9A 4DG9A 2K93A 2K0YA 3CMEP 3G29A 2K5XA 2JYLA 1JJ2O 4XROA 3GKLC 2XV6A 2MF4A 1VKUA 5KP7B 2GZGA 3G71P 2LL8A 2K92A 1W2BO 4U0BA 1YJNP 2ONTA 2PENA 4U0FA 2GZFA 2EIAA 3DS2A 2MY5A 4COPA 1ACPA 1NQ4A 4QNBA 1QVFO 4H2WC 3DS1A 3B4QA 1Q81Q 5HV8A 2PY8A 3G6EP 3DS4A 4H2YC 1QRJA 2Z44A 2FQ1A 5HGNA 2WPTA 2JU1A 1Z6MA 4BPGA 1KQSO 2L6EA 3G0VA 2M8NA 2JQ4A 3LRYA 5HGOA 3WBHA 3NTEA 1K8AQ 1VQ7P 3GZLA 3NY7B 1ZMBA 1M6NA 2MD9A 3B5IA 3GZMA 2QNWA 1YI2P 1DV5A 4M0IA 2CWOA 5KP8B 5EW5E 2LIWA 2GDWA 3I55P 1K73Q 2KG6A 2FADA 4PH1A 1VQ8P 3RG6C 2JGPA 2JB0A 2L22A 1QVGO 3DPHA 2MR8A 1S72P 2VLOA 4R0MA 1A8OA 2KGAA 2LOLA 1X3OA 2GDYA 4CA3A 1YJWP 3HYBA 5BS2A 4XRQA 1IUQA 5HGMA 1AYIA 1E6JP 3CC4P 1M90Q 3G26A 1VQOP 1VQ6P 1BAJA 3EJEA 3CPWO 2KOOA 3M1MA 4U0AA 3RG2A 3CCVP 1VHNA 2OTLP 1HY8A 2MVVA 1NJIQ 5KP6B 1CEIA 2EFJA 4COCA 2DGYA 2XT1A 3E2DA 1FR2A 2XZ0D 4H2XC 5HVCA 1KC8Q 4BPFA 2KORA 2KGEA 3CCQP 1ZNVA 2CQ8A 5HGLA 3MGEA 1K30A 2N50A 5EJDA 2OARA 4QKOA 2VSQA 1N8RQ 1VQLP 5JPAA 4XFXA 2VLPA 2JYGA 1EMVA 4WYMA 2JBGA 3CCSP 2FACA 4U0CA 1EIAA 2KWLA 2AVAA 3CMAP 1YITP 2NO8A 2XXMA 1VQPP 2BHVA 2E1MA 4PXHB 1F80D 5F2OA 3CCUP 1VQNP 3G1IA 4F37A 1Q82Q 2PEMA 1VQ4P 2KGCA 2Z46A 1EOQA 2CNRA 2PNGA 2JAZA 1VQKP 2FVFA 2L0QA 2N5HA 2GZEA 2PEIA 3G21A 2OTJP 3DS5A 4IZ6A 3HZQA 2LMLA 3DS0A 1VQ9P 1IMPA 2EHSA 1RO2A 3GJNA 3VRLC 1VQMP 2KGDA 4U0EA 2QEXP 1YIJP 1E0HA 2DNWA 4XFZA 2KOQA 2K0DX 2Z45A 2K94A 2LKIA 2K2QA 3CD6P 4U0DA 1KLPA 2VLNA 1K9MQ 2BUOA 1DNYA 1IMQA 3DTJA 2MR7A 3I56P 1A43A 1M1KQ 5F2NA 1AUMA 2KG8A 3CCMP 2X2BA 1L0IA 2KOSA 1BXIA 2AFEA 2AF8A 1Q86Q 2KOPA 2QA4P 4XFYA 1VQ5P 1GXGA 2GYKA 1MZ8A 2ROQA 2ERHA 3G4SP 3EJBA 3CC7P 2FVEA 1Q7YQ 1M6EX 2KR5A
chains in the Genus database with same CATH topology
1Q82Q 2PEMA 3G71P 1VQ4P 3H4EA 2Z46A 1YJWP 1W2BO 3CCLP 1EOQA 3HYBA 2PEQA 5BS2A 2M8PA 4U0BA 2PEJA 1KD1Q 4XRQA 1YJNP 1IUQA 5HGMA 5BS1A 2ONTA 2PENA 4U0FA 1VQKP 2EIAA 3DS2A 4COPA 2PEKA 1YHQP 3G28A 1E6JP 3CC4P 1M90Q 4QNBA 3G26A 1QVFO 2PEIA 1VQOP 1VQ6P 1BAJA 3DS1A 3G21A 2OTJP 3CPWO 1Q81Q 3M1MA 4U0AA 3DS5A 3G1GA 3CCVP 1YJ9P 2OTLP 2PY8A 3HZQA 3DS0A 1NJIQ 2EFJA 3G6EP 3DS4A 4GR6A 1VQ9P 1RO2A 4COCA 3VRLC 1QRJA 2DGYA 2XT1A 2Z44A 4IPYA 1VQMP 3E2DA 4U0EA 2QEXP 4GR2A 1KC8Q 5DCKA 5HGNA 3CCJP 1YIJP 2PEOA 3CCQP 1KQSO 3CXCO 4XFZA 2P9XA 1D1DA 1RNIA 2L6EA 5HGLA 3G0VA 1K30A 3MGEA 2M8NA 3H47A 2OARA 3LRYA 1RO0A 5HGOA 3WBHA 3CCEP 5I4TG 3NTEA 2Z45A 1N8RQ 1K8AQ 2KODA 1VQLP 3CC2P 1VQ7P 5JPAA 1M74A 3CD6P 1ZMBA 2LF4A 4U0DA 3H0DA 1M6NA 1K9MQ 2BUOA 4XFXA 2JYGA 2JO0A 3B5IA 3DTJA 4WYMA 3I56P 1A43A 1YI2P 5F2NA 1M1KQ 3P05A 4M0IA 1AUMA 3Q20A 3DS3A 3CCSP 4U0CA 5F2KA 4PH0A 2CWOA 3CCMP 1EIAA 2M8LA 1Q86Q 3I55P 3CCRP 1K73Q 4PH1A 1VQ8P 2QA4P 4XFYA 3RG6C 3CMAP 1VQ5P 2EG5A 1YITP 3OW2O 2XXMA 1VQPP 1QVGO 3DPHA 2BHVA 3CMEP 2E1MA 3G4SP 3G29A 1JJ2O 2JYLA 3CC7P 1S72P 4XROA 2XV6A 5F2OA 3CCUP 1A8OA 1Q7YQ 1VQNP 3G1IA 1M6EX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P05 A;  4M0I A;  1AUM A;  4U0A A;  3DS5 A;  3G1G A;  3H4E A;  3DS3 A;  4U0C A;  4XFZ A;  4PH0 A;  1D1D A;  2L6E A;  1EOQ A;  1EIA A;  5HGL A;  2M8P A;  3DS0 A;  3G0V A;  3MGE A;  4U0B A;  2M8N A;  2M8L A;  4XRQ A;  4PH1 A;  3DS4 A;  5HGM A;  2ONT A;  3H47 A;  4XFY A;  4U0F A;  3LRY A;  5HGO A;  2EIA A;  3DS2 A;  4COP A;  3NTE A;  4COC A;  2XXM A;  5I4T G;  2KOD A;  3VRL C;  1QRJ A;  2XT1 A;  3DPH A;  4IPY A;  5JPA A;  3G28 A;  1E6J P;  4QNB A;  3G29 A;  3G26 A;  2JYL A;  2LF4 A;  4U0E A;  4U0D A;  4XRO A;  2BUO A;  2XV6 A;  4XFX A;  2JYG A;  5DCK A;  2JO0 A;  5HGN A;  1A8O A;  3DTJ A;  1BAJ A;  3DS1 A;  3G1I A;  4WYM A;  3G21 A;  1A43 A; 
#chains in the Genus database with same CATH topology
 4UHP B;  3H4E A;  1AF8 A;  3CCL P;  2L9F A;  2PEQ A;  2M8P A;  2PEJ A;  1KD1 Q;  5CZD B;  5BS1 A;  2PEK A;  1YHQ P;  3G28 A;  2FQ0 A;  2GZI A;  2CG5 B;  1GPJ A;  2LPK A;  1HQB A;  3G1G A;  1YJ9 P;  2KW2 A;  7CEI A;  2L4B A;  3CE7 A;  4MRT C;  4GR6 A;  2FQ2 A;  2N5I A;  2GZJ A;  2FVA A;  4PWV B;  2VLQ A;  4IPY A;  3LMO A;  2LTE A;  2AFD A;  4GR2 A;  5DCK A;  1L0H A;  3CCJ P;  2PEO A;  2CGQ A;  1GXH A;  3CXC O;  2P9X A;  1D1D A;  1RNI A;  2EHT A;  2LIU A;  3H47 A;  4HKG A;  1UJZ A;  3U43 A;  3CCE P;  1RO0 A;  2FAE A;  4NEO A;  5I4T G;  2KOD A;  3CC2 P;  1M74 A;  1UNK A;  2LF4 A;  3H0D A;  2JU2 A;  2XZ1 C;  2JO0 A;  1T8K A;  2N98 A;  2M5R A;  2MVU A;  3P05 A;  3Q20 A;  2K0X A;  2GDX A;  2N6Z A;  3DS3 A;  4PH0 A;  5F2K A;  2N6Y A;  2M8L A;  2FHS C;  3CCR P;  4BPH A;  3EJD A;  2EG5 A;  1OR5 A;  3OW2 O;  2KG9 A;  4DG9 A;  2K93 A;  2K0Y A;  3CME P;  3G29 A;  2K5X A;  2JYL A;  1JJ2 O;  4XRO A;  3GKL C;  2XV6 A;  2MF4 A;  1VKU A;  5KP7 B;  2GZG A;  3G71 P;  2LL8 A;  2K92 A;  1W2B O;  4U0B A;  1YJN P;  2ONT A;  2PEN A;  4U0F A;  2GZF A;  2EIA A;  3DS2 A;  2MY5 A;  4COP A;  1ACP A;  1NQ4 A;  4QNB A;  1QVF O;  4H2W C;  3DS1 A;  3B4Q A;  1Q81 Q;  5HV8 A;  2PY8 A;  3G6E P;  3DS4 A;  4H2Y C;  1QRJ A;  2Z44 A;  2FQ1 A;  5HGN A;  2WPT A;  2JU1 A;  1Z6M A;  4BPG A;  1KQS O;  2L6E A;  3G0V A;  2M8N A;  2JQ4 A;  3LRY A;  5HGO A;  3WBH A;  3NTE A;  1K8A Q;  1VQ7 P;  3GZL A;  3NY7 B;  1ZMB A;  1M6N A;  2MD9 A;  3B5I A;  3GZM A;  2QNW A;  1YI2 P;  1DV5 A;  4M0I A;  2CWO A;  5KP8 B;  5EW5 E;  2LIW A;  2GDW A;  3I55 P;  1K73 Q;  2KG6 A;  2FAD A;  4PH1 A;  1VQ8 P;  3RG6 C;  2JGP A;  2JB0 A;  2L22 A;  1QVG O;  3DPH A;  2MR8 A;  1S72 P;  2VLO A;  4R0M A;  1A8O A;  2KGA A;  2LOL A;  1X3O A;  2GDY A;  4CA3 A;  1YJW P;  3HYB A;  5BS2 A;  4XRQ A;  1IUQ A;  5HGM A;  1AYI A;  1E6J P;  3CC4 P;  1M90 Q;  3G26 A;  1VQO P;  1VQ6 P;  1BAJ A;  3EJE A;  3CPW O;  2KOO A;  3M1M A;  4U0A A;  3RG2 A;  3CCV P;  1VHN A;  2OTL P;  1HY8 A;  2MVV A;  1NJI Q;  5KP6 B;  1CEI A;  2EFJ A;  4COC A;  2DGY A;  2XT1 A;  3E2D A;  1FR2 A;  2XZ0 D;  4H2X C;  5HVC A;  1KC8 Q;  4BPF A;  2KOR A;  2KGE A;  3CCQ P;  1ZNV A;  2CQ8 A;  5HGL A;  3MGE A;  1K30 A;  2N50 A;  5EJD A;  2OAR A;  4QKO A;  2VSQ A;  1N8R Q;  1VQL P;  5JPA A;  4XFX A;  2VLP A;  2JYG A;  1EMV A;  4WYM A;  2JBG A;  3CCS P;  2FAC A;  4U0C A;  1EIA A;  2KWL A;  2AVA A;  3CMA P;  1YIT P;  2NO8 A;  2XXM A;  1VQP P;  2BHV A;  2E1M A;  4PXH B;  1F80 D;  5F2O A;  3CCU P;  1VQN P;  3G1I A;  4F37 A;  1Q82 Q;  2PEM A;  1VQ4 P;  2KGC A;  2Z46 A;  1EOQ A;  2CNR A;  2PNG A;  2JAZ A;  1VQK P;  2FVF A;  2L0Q A;  2N5H A;  2GZE A;  2PEI A;  3G21 A;  2OTJ P;  3DS5 A;  4IZ6 A;  3HZQ A;  2LML A;  3DS0 A;  1VQ9 P;  1IMP A;  2EHS A;  1RO2 A;  3GJN A;  3VRL C;  1VQM P;  2KGD A;  4U0E A;  2QEX P;  1YIJ P;  1E0H A;  2DNW A;  4XFZ A;  2KOQ A;  2K0D X;  2Z45 A;  2K94 A;  2LKI A;  2K2Q A;  3CD6 P;  4U0D A;  1KLP A;  2VLN A;  1K9M Q;  2BUO A;  1DNY A;  1IMQ A;  3DTJ A;  2MR7 A;  3I56 P;  1A43 A;  1M1K Q;  5F2N A;  1AUM A;  2KG8 A;  3CCM P;  2X2B A;  1L0I A;  2KOS A;  1BXI A;  2AFE A;  2AF8 A;  1Q86 Q;  2KOP A;  2QA4 P;  4XFY A;  1VQ5 P;  1GXG A;  2GYK A;  1MZ8 A;  2ROQ A;  2ERH A;  3G4S P;  3EJB A;  3CC7 P;  2FVE A;  1Q7Y Q;  1M6E X;  2KR5 A; 
#chains in the Genus database with same CATH homology
 1Q82 Q;  2PEM A;  3G71 P;  1VQ4 P;  3H4E A;  2Z46 A;  1YJW P;  1W2B O;  3CCL P;  1EOQ A;  3HYB A;  2PEQ A;  5BS2 A;  2M8P A;  4U0B A;  2PEJ A;  1KD1 Q;  4XRQ A;  1YJN P;  1IUQ A;  5HGM A;  5BS1 A;  2ONT A;  2PEN A;  4U0F A;  1VQK P;  2EIA A;  3DS2 A;  4COP A;  2PEK A;  1YHQ P;  3G28 A;  1E6J P;  3CC4 P;  1M90 Q;  4QNB A;  3G26 A;  1QVF O;  2PEI A;  1VQO P;  1VQ6 P;  1BAJ A;  3DS1 A;  3G21 A;  2OTJ P;  3CPW O;  1Q81 Q;  3M1M A;  4U0A A;  3DS5 A;  3G1G A;  3CCV P;  1YJ9 P;  2OTL P;  2PY8 A;  3HZQ A;  3DS0 A;  1NJI Q;  2EFJ A;  3G6E P;  3DS4 A;  4GR6 A;  1VQ9 P;  1RO2 A;  4COC A;  3VRL C;  1QRJ A;  2DGY A;  2XT1 A;  2Z44 A;  4IPY A;  1VQM P;  3E2D A;  4U0E A;  2QEX P;  4GR2 A;  1KC8 Q;  5DCK A;  5HGN A;  3CCJ P;  1YIJ P;  2PEO A;  3CCQ P;  1KQS O;  3CXC O;  4XFZ A;  2P9X A;  1D1D A;  1RNI A;  2L6E A;  5HGL A;  3G0V A;  1K30 A;  3MGE A;  2M8N A;  3H47 A;  2OAR A;  3LRY A;  1RO0 A;  5HGO A;  3WBH A;  3CCE P;  5I4T G;  3NTE A;  2Z45 A;  1N8R Q;  1K8A Q;  2KOD A;  1VQL P;  3CC2 P;  1VQ7 P;  5JPA A;  1M74 A;  3CD6 P;  1ZMB A;  2LF4 A;  4U0D A;  3H0D A;  1M6N A;  1K9M Q;  2BUO A;  4XFX A;  2JYG A;  2JO0 A;  3B5I A;  3DTJ A;  4WYM A;  3I56 P;  1A43 A;  1YI2 P;  5F2N A;  1M1K Q;  3P05 A;  4M0I A;  1AUM A;  3Q20 A;  3DS3 A;  3CCS P;  4U0C A;  5F2K A;  4PH0 A;  2CWO A;  3CCM P;  1EIA A;  2M8L A;  1Q86 Q;  3I55 P;  3CCR P;  1K73 Q;  4PH1 A;  1VQ8 P;  2QA4 P;  4XFY A;  3RG6 C;  3CMA P;  1VQ5 P;  2EG5 A;  1YIT P;  3OW2 O;  2XXM A;  1VQP P;  1QVG O;  3DPH A;  2BHV A;  3CME P;  2E1M A;  3G4S P;  3G29 A;  1JJ2 O;  2JYL A;  3CC7 P;  1S72 P;  4XRO A;  2XV6 A;  5F2O A;  3CCU P;  1A8O A;  1Q7Y Q;  1VQN P;  3G1I A;  1M6E X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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