3DS3A

Hiv-1 capsid c-terminal domain mutant (y169a) in complex with an inhibitor of particle assembly (cai)
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
73
structure length
73
Chain Sequence
TSILDIRQGPKEPFRDYVDRFAKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPGATLEEMMTACQG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein.
pubmed doi rcsb
molecule tags Viral protein
source organism Human immunodeficiency virus 1
molecule keywords HIV-1 CAPSID PROTEIN
total genus 26
structure length 73
sequence length 73
chains with identical sequence B
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2008-07-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.30 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A 3ds3A00
4U0AA 5HGNA 2XT1A 3LRYA 4QNBA 4XFXA 4WYMA 1EIAA 3DS3A 3DS2A 3G29A 3DS1A 4U0BA 4U0CA 2M8NA 3DTJA 4U0EA 4M0IA 4IPYA 3DS0A 1E6JP 3H4EA 1A43A 2JYGA 3G21A 2L6EA 4PH1A 1QRJA 4PH0A 3G1IA 3G28A 2M8LA 3H47A 1EOQA 2XV6A 3G1GA 4XFZA 5HGOA 3VRLC 4XROA 3DS4A 5I4TG 1A8OA 2M8PA 1D1DA 1BAJA 2JO0A 2ONTA 3G26A 5HGLA 5HGMA 3P05A 5JPAA 2XXMA 4COPA 4U0FA 3NTEA 3DPHA 5DCKA 4U0DA 3G0VA 2LF4A 2KODA 2BUOA 3MGEA 2JYLA 4COCA 1AUMA 4XFYA 4XRQA 2EIAA 3DS5A
chains in the Genus database with same CATH superfamily
2MR8A 4U0AA 3G29A 2FVFA 2FVEA 1MZ8A 2EFJA 2XV6A 1Q7YQ 5BS1A 5HGMA 1KQSO 2FQ2A 2DGYA 2K0DX 1IMQA 1GXHA 2FVAA 3DS5A 3CCLP 3RG6C 1VKUA 3CCUP 4U0EA 3U43A 2Z44A 1E6JP 5F2OA 1RO0A 2JAZA 2LKIA 2WPTA 2GDXA 3GKLC 3CXCO 2MVVA 3G6EP 1S72P 2LTEA 2CNRA 2L22A 2EG5A 1IMPA 1BAJA 2MD9A 2PNGA 5F2NA 4QKOA 1W2BO 2KODA 2BUOA 5HGNA 3DS3A 4MRTC 4BPFA 2FACA 2KORA 2JYGA 2Z45A 2PEOA 3I56P 2KOOA 1VQ4P 2MY5A 4CA3A 2GZEA 1E0HA 1D1DA 2JO0A 2EHTA 3LMOA 1YJ9P 2KGAA 4U0DA 4BPGA 2BHVA 2QEXP 1ACPA 1AUMA 4DG9A 1DV5A 2OARA 2XT1A 1JJ2O 4QNBA 3CD6P 4WYMA 1EIAA 2PENA 1VQ5P 4M0IA 2VLOA 3GZMA 1L0IA 2N6ZA 3CCEP 3HZQA 1YITP 1M90Q 2LIWA 2M8PA 4F37A 5HVCA 2KOSA 5HGLA 2JB0A 3H0DA 1GXGA 1QVGO 1ZMBA 3DS1A 2GZGA 2M5RA 2M8NA 3DTJA 3EJBA 3G28A 2KG8A 2XZ0D 1GPJA 3EJDA 1KD1Q 4GR2A 5JPAA 2VLPA 3I55P 4U0FA 3G0VA 2PEKA 2NO8A 2FQ1A 1VQMP 7CEIA 4UHPB 2PY8A 3WBHA 3EJEA 3CMEP 4PH1A 2LOLA 2GZJA 4XROA 1OR5A 1T8KA 3G4SP 1A8OA 2LIUA 2XXMA 2JU1A 2FQ0A 3CCRP 5KP6B 2N5IA 1UNKA 1M1KQ 2N50A 2EIAA 4XFXA 2LPKA 2QNWA 4PXHB 1K30A 3GJNA 1VQOP 2MVUA 1KLPA 2DNWA 1VQNP 2KGDA 3VRLC 2KGCA 2N6YA 2L4BA 1L0HA 1CEIA 3DPHA 3M1MA 4GR6A 2JQ4A 5F2KA 3CCQP 1YIJP 3DS2A 1QVFO 2AVAA 1IUQA 2KOPA 3CCVP 1K73Q 2OTJP 2K92A 4BPHA 2L9FA 4H2YC 4PWVB 1VHNA 2CGQA 4XRQA 2GDWA 2VLQA 2KW2A 2K93A 2LL8A 2GDYA 5BS2A 2M8LA 1N8RQ 1EOQA 1HY8A 1M74A 1YI2P 2ERHA 2K2QA 5EW5E 3CC7P 2L0QA 5DCKA 4H2XC 1YJWP 2VSQA 1NJIQ 3LRYA 2PEJA 2N98A 2AF8A 4U0BA 1VQPP 1Z6MA 2KR5A 4IPYA 3CC2P 1A43A 4NEOA 2CG5B 3G21A 1EMVA 3CC4P 2KWLA 3E2DA 2K0YA 1VQ9P 3P05A 4COPA 3NTEA 1AYIA 4H2WC 5KP8B 3OW2O 4U0CA 1KC8Q 3CMAP 1FR2A 1Q81Q 1YJNP 2L6EA 3G1IA 2LMLA 2PEMA 1AF8A 1NQ4A 5HGOA 2KG6A 1RNIA 5HV8A 2GYKA 2AFDA 1M6NA 3GZLA 1Q82Q 2PEIA 2XZ1C 2MR7A 3NY7B 3RG2A 2PEQA 3CE7A 4R0MA 4PH0A 1QRJA 3H47A 2CWOA 4XFZA 5KP7B 3B4QA 1VQ8P 4IZ6A 2GZFA 2LF4A 3MGEA 3G71P 2JGPA 2JU2A 1Q86Q 1UJZA 3CCMP 1DNYA 1M6EX 5EJDA 1VQ7P 3G1GA 2OTLP 2Z46A 2K5XA 3DS4A 2CQ8A 2MF4A 2ONTA 1VQ6P 2FHSC 3CCJP 1BXIA 2P9XA 2FAEA 1VQLP 3DS0A 2QA4P 2AFEA 2GZIA 2JBGA 2N5HA 1RO2A 3H4EA 1ZNVA 2KOQA 5I4TG 2X2BA 1F80D 2K94A 1K8AQ 3CPWO 3CCSP 1YHQP 3B5IA 2KG9A 4XFYA 1K9MQ 2E1MA 4HKGA 4COCA 2VLNA 5CZDB 1VQKP 3HYBA 2KGEA 1X3OA 3G26A 1HQBA 2EHSA 3Q20A 2ROQA 2JYLA 2FADA 2K0XA
chains in the Genus database with same CATH topology
4U0AA 2PEIA 2OARA 2XT1A 1YIJP 4QNBA 1JJ2O 4WYMA 1EIAA 3DS2A 3CD6P 2PENA 3G29A 1QVFO 1VQ5P 2PEQA 4M0IA 1IUQA 4PH0A 3CCEP 1QRJA 3HZQA 3H47A 2EFJA 2CWOA 4XFZA 2XV6A 3CCVP 1YITP 1M90Q 2M8PA 1Q7YQ 1K73Q 1VQ8P 5BS1A 5HGMA 5HGLA 1KQSO 2OTJP 2DGYA 3H0DA 2LF4A 3MGEA 3G71P 4XRQA 1Q86Q 1QVGO 3DS5A 3CCLP 3RG6C 1ZMBA 3DS1A 3CCMP 2M8NA 3DTJA 3CCUP 5BS2A 4U0EA 1M6EX 2Z44A 1E6JP 5F2OA 1RO0A 3G28A 1VQ7P 2M8LA 1N8RQ 1EOQA 3G1GA 2OTLP 2Z46A 1M74A 1KD1Q 3DS4A 4GR2A 1YI2P 2ONTA 5JPAA 3I55P 1VQ6P 3CC7P 4U0FA 3CCJP 5DCKA 3CXCO 3G0VA 2PEKA 2P9XA 1VQLP 1YJWP 3DS0A 3G6EP 2QA4P 1S72P 1NJIQ 1VQMP 3LRYA 2PEJA 4U0BA 1VQPP 2PY8A 3WBHA 4IPYA 1RO2A 1A43A 3H4EA 3CC2P 3CMEP 3G21A 4PH1A 3CC4P 2EG5A 3E2DA 4XROA 5I4TG 3G4SP 1A8OA 1BAJA 1K8AQ 1VQ9P 3P05A 2XXMA 4COPA 5F2NA 3CPWO 3NTEA 1W2BO 3CCSP 3CCRP 1YHQP 2KODA 3B5IA 2BUOA 4XFYA 1K9MQ 1M1KQ 2E1MA 2EIAA 4COCA 5HGNA 4XFXA 3OW2O 3DS3A 4U0CA 1KC8Q 3CMAP 1K30A 1VQOP 2JYGA 1Q81Q 1YJNP 1VQKP 2L6EA 2Z45A 2PEOA 3G1IA 1VQNP 3I56P 3HYBA 1VQ4P 2PEMA 5HGOA 3VRLC 1D1DA 2JO0A 3G26A 1RNIA 1YJ9P 3DPHA 3Q20A 4U0DA 2BHVA 2QEXP 3M1MA 4GR6A 2JYLA 1AUMA 5F2KA 1M6NA 3CCQP 1Q82Q
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U0A A;  5HGN A;  2XT1 A;  3LRY A;  4QNB A;  4XFX A;  4WYM A;  1EIA A;  3DS3 A;  3DS2 A;  3G29 A;  3DS1 A;  4U0B A;  4U0C A;  2M8N A;  3DTJ A;  4U0E A;  4M0I A;  4IPY A;  3DS0 A;  1E6J P;  3H4E A;  1A43 A;  2JYG A;  3G21 A;  2L6E A;  4PH1 A;  1QRJ A;  4PH0 A;  3G1I A;  3G28 A;  2M8L A;  3H47 A;  1EOQ A;  2XV6 A;  3G1G A;  4XFZ A;  5HGO A;  3VRL C;  4XRO A;  3DS4 A;  5I4T G;  1A8O A;  2M8P A;  1D1D A;  1BAJ A;  2JO0 A;  2ONT A;  3G26 A;  5HGL A;  5HGM A;  3P05 A;  5JPA A;  2XXM A;  4COP A;  4U0F A;  3NTE A;  3DPH A;  5DCK A;  4U0D A;  3G0V A;  2LF4 A;  2KOD A;  2BUO A;  3MGE A;  2JYL A;  4COC A;  1AUM A;  4XFY A;  4XRQ A;  2EIA A;  3DS5 A; 
#chains in the Genus database with same CATH topology
 2MR8 A;  4U0A A;  3G29 A;  2FVF A;  2FVE A;  1MZ8 A;  2EFJ A;  2XV6 A;  1Q7Y Q;  5BS1 A;  5HGM A;  1KQS O;  2FQ2 A;  2DGY A;  2K0D X;  1IMQ A;  1GXH A;  2FVA A;  3DS5 A;  3CCL P;  3RG6 C;  1VKU A;  3CCU P;  4U0E A;  3U43 A;  2Z44 A;  1E6J P;  5F2O A;  1RO0 A;  2JAZ A;  2LKI A;  2WPT A;  2GDX A;  3GKL C;  3CXC O;  2MVV A;  3G6E P;  1S72 P;  2LTE A;  2CNR A;  2L22 A;  2EG5 A;  1IMP A;  1BAJ A;  2MD9 A;  2PNG A;  5F2N A;  4QKO A;  1W2B O;  2KOD A;  2BUO A;  5HGN A;  3DS3 A;  4MRT C;  4BPF A;  2FAC A;  2KOR A;  2JYG A;  2Z45 A;  2PEO A;  3I56 P;  2KOO A;  1VQ4 P;  2MY5 A;  4CA3 A;  2GZE A;  1E0H A;  1D1D A;  2JO0 A;  2EHT A;  3LMO A;  1YJ9 P;  2KGA A;  4U0D A;  4BPG A;  2BHV A;  2QEX P;  1ACP A;  1AUM A;  4DG9 A;  1DV5 A;  2OAR A;  2XT1 A;  1JJ2 O;  4QNB A;  3CD6 P;  4WYM A;  1EIA A;  2PEN A;  1VQ5 P;  4M0I A;  2VLO A;  3GZM A;  1L0I A;  2N6Z A;  3CCE P;  3HZQ A;  1YIT P;  1M90 Q;  2LIW A;  2M8P A;  4F37 A;  5HVC A;  2KOS A;  5HGL A;  2JB0 A;  3H0D A;  1GXG A;  1QVG O;  1ZMB A;  3DS1 A;  2GZG A;  2M5R A;  2M8N A;  3DTJ A;  3EJB A;  3G28 A;  2KG8 A;  2XZ0 D;  1GPJ A;  3EJD A;  1KD1 Q;  4GR2 A;  5JPA A;  2VLP A;  3I55 P;  4U0F A;  3G0V A;  2PEK A;  2NO8 A;  2FQ1 A;  1VQM P;  7CEI A;  4UHP B;  2PY8 A;  3WBH A;  3EJE A;  3CME P;  4PH1 A;  2LOL A;  2GZJ A;  4XRO A;  1OR5 A;  1T8K A;  3G4S P;  1A8O A;  2LIU A;  2XXM A;  2JU1 A;  2FQ0 A;  3CCR P;  5KP6 B;  2N5I A;  1UNK A;  1M1K Q;  2N50 A;  2EIA A;  4XFX A;  2LPK A;  2QNW A;  4PXH B;  1K30 A;  3GJN A;  1VQO P;  2MVU A;  1KLP A;  2DNW A;  1VQN P;  2KGD A;  3VRL C;  2KGC A;  2N6Y A;  2L4B A;  1L0H A;  1CEI A;  3DPH A;  3M1M A;  4GR6 A;  2JQ4 A;  5F2K A;  3CCQ P;  1YIJ P;  3DS2 A;  1QVF O;  2AVA A;  1IUQ A;  2KOP A;  3CCV P;  1K73 Q;  2OTJ P;  2K92 A;  4BPH A;  2L9F A;  4H2Y C;  4PWV B;  1VHN A;  2CGQ A;  4XRQ A;  2GDW A;  2VLQ A;  2KW2 A;  2K93 A;  2LL8 A;  2GDY A;  5BS2 A;  2M8L A;  1N8R Q;  1EOQ A;  1HY8 A;  1M74 A;  1YI2 P;  2ERH A;  2K2Q A;  5EW5 E;  3CC7 P;  2L0Q A;  5DCK A;  4H2X C;  1YJW P;  2VSQ A;  1NJI Q;  3LRY A;  2PEJ A;  2N98 A;  2AF8 A;  4U0B A;  1VQP P;  1Z6M A;  2KR5 A;  4IPY A;  3CC2 P;  1A43 A;  4NEO A;  2CG5 B;  3G21 A;  1EMV A;  3CC4 P;  2KWL A;  3E2D A;  2K0Y A;  1VQ9 P;  3P05 A;  4COP A;  3NTE A;  1AYI A;  4H2W C;  5KP8 B;  3OW2 O;  4U0C A;  1KC8 Q;  3CMA P;  1FR2 A;  1Q81 Q;  1YJN P;  2L6E A;  3G1I A;  2LML A;  2PEM A;  1AF8 A;  1NQ4 A;  5HGO A;  2KG6 A;  1RNI A;  5HV8 A;  2GYK A;  2AFD A;  1M6N A;  3GZL A;  1Q82 Q;  2PEI A;  2XZ1 C;  2MR7 A;  3NY7 B;  3RG2 A;  2PEQ A;  3CE7 A;  4R0M A;  4PH0 A;  1QRJ A;  3H47 A;  2CWO A;  4XFZ A;  5KP7 B;  3B4Q A;  1VQ8 P;  4IZ6 A;  2GZF A;  2LF4 A;  3MGE A;  3G71 P;  2JGP A;  2JU2 A;  1Q86 Q;  1UJZ A;  3CCM P;  1DNY A;  1M6E X;  5EJD A;  1VQ7 P;  3G1G A;  2OTL P;  2Z46 A;  2K5X A;  3DS4 A;  2CQ8 A;  2MF4 A;  2ONT A;  1VQ6 P;  2FHS C;  3CCJ P;  1BXI A;  2P9X A;  2FAE A;  1VQL P;  3DS0 A;  2QA4 P;  2AFE A;  2GZI A;  2JBG A;  2N5H A;  1RO2 A;  3H4E A;  1ZNV A;  2KOQ A;  5I4T G;  2X2B A;  1F80 D;  2K94 A;  1K8A Q;  3CPW O;  3CCS P;  1YHQ P;  3B5I A;  2KG9 A;  4XFY A;  1K9M Q;  2E1M A;  4HKG A;  4COC A;  2VLN A;  5CZD B;  1VQK P;  3HYB A;  2KGE A;  1X3O A;  3G26 A;  1HQB A;  2EHS A;  3Q20 A;  2ROQ A;  2JYL A;  2FAD A;  2K0X A; 
#chains in the Genus database with same CATH homology
 4U0A A;  2PEI A;  2OAR A;  2XT1 A;  1YIJ P;  4QNB A;  1JJ2 O;  4WYM A;  1EIA A;  3DS2 A;  3CD6 P;  2PEN A;  3G29 A;  1QVF O;  1VQ5 P;  2PEQ A;  4M0I A;  1IUQ A;  4PH0 A;  3CCE P;  1QRJ A;  3HZQ A;  3H47 A;  2EFJ A;  2CWO A;  4XFZ A;  2XV6 A;  3CCV P;  1YIT P;  1M90 Q;  2M8P A;  1Q7Y Q;  1K73 Q;  1VQ8 P;  5BS1 A;  5HGM A;  5HGL A;  1KQS O;  2OTJ P;  2DGY A;  3H0D A;  2LF4 A;  3MGE A;  3G71 P;  4XRQ A;  1Q86 Q;  1QVG O;  3DS5 A;  3CCL P;  3RG6 C;  1ZMB A;  3DS1 A;  3CCM P;  2M8N A;  3DTJ A;  3CCU P;  5BS2 A;  4U0E A;  1M6E X;  2Z44 A;  1E6J P;  5F2O A;  1RO0 A;  3G28 A;  1VQ7 P;  2M8L A;  1N8R Q;  1EOQ A;  3G1G A;  2OTL P;  2Z46 A;  1M74 A;  1KD1 Q;  3DS4 A;  4GR2 A;  1YI2 P;  2ONT A;  5JPA A;  3I55 P;  1VQ6 P;  3CC7 P;  4U0F A;  3CCJ P;  5DCK A;  3CXC O;  3G0V A;  2PEK A;  2P9X A;  1VQL P;  1YJW P;  3DS0 A;  3G6E P;  2QA4 P;  1S72 P;  1NJI Q;  1VQM P;  3LRY A;  2PEJ A;  4U0B A;  1VQP P;  2PY8 A;  3WBH A;  4IPY A;  1RO2 A;  1A43 A;  3H4E A;  3CC2 P;  3CME P;  3G21 A;  4PH1 A;  3CC4 P;  2EG5 A;  3E2D A;  4XRO A;  5I4T G;  3G4S P;  1A8O A;  1BAJ A;  1K8A Q;  1VQ9 P;  3P05 A;  2XXM A;  4COP A;  5F2N A;  3CPW O;  3NTE A;  1W2B O;  3CCS P;  3CCR P;  1YHQ P;  2KOD A;  3B5I A;  2BUO A;  4XFY A;  1K9M Q;  1M1K Q;  2E1M A;  2EIA A;  4COC A;  5HGN A;  4XFX A;  3OW2 O;  3DS3 A;  4U0C A;  1KC8 Q;  3CMA P;  1K30 A;  1VQO P;  2JYG A;  1Q81 Q;  1YJN P;  1VQK P;  2L6E A;  2Z45 A;  2PEO A;  3G1I A;  1VQN P;  3I56 P;  3HYB A;  1VQ4 P;  2PEM A;  5HGO A;  3VRL C;  1D1D A;  2JO0 A;  3G26 A;  1RNI A;  1YJ9 P;  3DPH A;  3Q20 A;  4U0D A;  2BHV A;  2QEX P;  3M1M A;  4GR6 A;  2JYL A;  1AUM A;  5F2K A;  1M6N A;  3CCQ P;  1Q82 Q; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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