3GKLC

Following evolutionary paths to high affinity and selectivity protein-protein interactions using colicin7 and immunity proteins
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
82
structure length
82
Chain Sequence
KHSISDYTEAEFLQLVATICDADATSEEELDKLITHFGEMTEHPSGSDLIYYPEEGDDDSPSGIVNTVKQWRAANGKSGFKQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Following evolutionary paths to high affinity and selectivity protein-protein interactions
rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Colicin-E9 immunity protein
total genus 24
structure length 82
sequence length 82
chains with identical sequence D
ec nomenclature
pdb deposition date 2009-03-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01320 Colicin_Pyocin Colicin immunity protein / pyocin immunity protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.20 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Colicin E immunity protein 3gklC00
7CEIA 1IMQA 2ERHA 2GZJA 1UNKA 2VLQA 2VLPA 3U43A 2JBGA 5EW5E 1MZ8A 1AYIA 1GXGA 2GZEA 3GJNA 2JAZA 1BXIA 2GZGA 1IMPA 1ZNVA 2NO8A 2VLOA 1UJZA 1CEIA 2VLNA 1E0HA 2GZIA 1EMVA 4UHPB 2GZFA 1FR2A 2JB0A 4F37A 4QKOA 2GYKA 2WPTA 1GXHA 2K0DX 3GKLC 2K5XA
chains in the Genus database with same CATH superfamily
1BAJA 1M1KQ 3GJNA 2JAZA 1VHNA 2LPKA 1VQNP 2ONTA 2K93A 1F80D 1ZNVA 1ZMBA 2PEMA 1L0IA 2EHSA 4PWVB 5BS1A 1K30A 3CXCO 5CZDB 2N50A 2M8PA 2CGQA 4COCA 4QKOA 4PXHB 2FHSC 1T8KA 2CG5B 7CEIA 2KG9A 4WYMA 2JYLA 2GZEA 2N6ZA 1RO2A 1BXIA 5BS2A 1M6NA 3CCUP 1CEIA 3P05A 1RNIA 2QNWA 4GR2A 1E6JP 2Z46A 1Z6MA 2M5RA 2JB0A 2MY5A 1YJ9P 2Z45A 2JBGA 5EW5E 1DNYA 2MR8A 5I4TG 2PEOA 4R0MA 3EJEA 2X2BA 2OTJP 3DS4A 4U0CA 1VQKP 2GZFA 2KOSA 4F37A 1A43A 4XFYA 1YHQP 2AFEA 2KODA 4BPHA 3G6EP 2K5XA 3EJDA 2P9XA 5F2OA 3LMOA 2K0YA 2EIAA 2GZGA 1QVGO 1VQMP 2MVVA 1D1DA 2FQ2A 1AUMA 5HVCA 1L0HA 1VQ5P 2FVAA 1M6EX 1EMVA 3MGEA 3CCEP 2LKIA 3WBHA 2KOPA 1DV5A 3CCSP 3G29A 3CCMP 2N5HA 1YIJP 3NTEA 1KD1Q 2NO8A 2JGPA 1IUQA 2EFJA 4DG9A 2MD9A 2AFDA 2GDXA 2LMLA 2E1MA 4COPA 1OR5A 3CMEP 2K0DX 3CCRP 3H0DA 3H47A 2VLPA 2PEJA 2XZ1C 2AVAA 1HQBA 1K8AQ 1VQOP 5KP6B 2KORA 3RG2A 4MRTC 4U0AA 3Q20A 1X3OA 2PEKA 2JU1A 2M8NA 3CE7A 2VLNA 1Q7YQ 2MVUA 1RO0A 1EOQA 2K92A 2FADA 2N5IA 3G4SP 2LOLA 2QA4P 3DS5A 2EHTA 2JYGA 5JPAA 4U0EA 1Q86Q 3GZMA 2LTEA 2FQ1A 3G21A 1EIAA 2OARA 3CPWO 3G28A 1KLPA 1AF8A 1IMPA 1M90Q 3VRLC 1KC8Q 3CC7P 1M74A 2DGYA 1FR2A 5HV8A 4NEOA 2FQ0A 4IPYA 2VLQA 3U43A 2KGEA 1A8OA 3DPHA 2VSQA 2LIWA 2KGDA 3EJBA 1KQSO 2FVEA 1VQPP 4BPGA 1VQ4P 2QEXP 1VQ8P 1Q81Q 2GYKA 4CA3A 1GXHA 4U0BA 1YJNP 2KGCA 3GZLA 4IZ6A 3CCQP 1YJWP 4QNBA 4PH0A 3G1GA 3CC4P 2N6YA 2CWOA 2MR7A 5F2NA 2KOQA 2KOOA 4M0IA 1YITP 2MF4A 2PEQA 3LRYA 1UNKA 2KG6A 1GXGA 2JO0A 2GDWA 2KG8A 3G26A 4GR6A 3CC2P 3CCLP 1ACPA 2FACA 5KP7B 2OTLP 2XXMA 3CD6P 4XFXA 4BPFA 2PEIA 2N98A 5HGNA 2AF8A 1IMQA 2ERHA 2GZJA 2GDYA 3DS0A 2CQ8A 1VQ6P 2JQ4A 1NQ4A 2L6EA 2VLOA 3DTJA 3CMAP 1W2BO 2KR5A 3DS3A 4U0DA 1VQ9P 3CCVP 3M1MA 4H2XC 4XRQA 2K0XA 1JJ2O 3G1IA 2DNWA 1AYIA 1Q82Q 3CCJP 1NJIQ 3RG6C 5KP8B 1UJZA 4PH1A 3I56P 1VQ7P 2GZIA 4U0FA 2K94A 2CNRA 5HGMA 2XZ0D 2L9FA 2FVFA 5F2KA 2KGAA 4XROA 1GPJA 3E2DA 3DS1A 2PNGA 1E0HA 4H2YC 2BHVA 1K9MQ 4UHPB 5HGOA 4H2WC 1YI2P 5EJDA 2XV6A 2ROQA 2KW2A 1K73Q 1QVFO 3B4QA 3I55P 2L0QA 2JU2A 5DCKA 4XFZA 2PENA 2LIUA 4HKGA 2L4BA 2M8LA 2LF4A 3NY7B 1S72P 2KWLA 2BUOA 3DS2A 1VQLP 1HY8A 2EG5A 3GKLC 3OW2O 3G0VA 1MZ8A 3B5IA 3HZQA 5HGLA 2FAEA 2L22A 1QRJA 2PY8A 2Z44A 2K2QA 2XT1A 3G71P 1N8RQ 1VKUA 2LL8A 3H4EA 3HYBA 2WPTA
chains in the Genus database with same CATH topology
7CEIA 1IMQA 2ERHA 2GZJA 1UNKA 2VLQA 2VLPA 3U43A 2JBGA 5EW5E 1MZ8A 1AYIA 1GXGA 2GZEA 3GJNA 2JAZA 1BXIA 2GZGA 1IMPA 1ZNVA 2NO8A 2VLOA 1UJZA 1CEIA 2VLNA 1E0HA 2GZIA 1EMVA 4UHPB 2GZFA 1FR2A 2JB0A 4F37A 4QKOA 2GYKA 2WPTA 1GXHA 2K0DX 3GKLC 2K5XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 7CEI A;  1IMQ A;  2ERH A;  2GZJ A;  1UNK A;  2VLQ A;  2VLP A;  3U43 A;  2JBG A;  5EW5 E;  1MZ8 A;  1AYI A;  1GXG A;  2GZE A;  3GJN A;  2JAZ A;  1BXI A;  2GZG A;  1IMP A;  1ZNV A;  2NO8 A;  2VLO A;  1UJZ A;  1CEI A;  2VLN A;  1E0H A;  2GZI A;  1EMV A;  4UHP B;  2GZF A;  1FR2 A;  2JB0 A;  4F37 A;  4QKO A;  2GYK A;  2WPT A;  1GXH A;  2K0D X;  3GKL C;  2K5X A; 
#chains in the Genus database with same CATH topology
 1BAJ A;  1M1K Q;  3GJN A;  2JAZ A;  1VHN A;  2LPK A;  1VQN P;  2ONT A;  2K93 A;  1F80 D;  1ZNV A;  1ZMB A;  2PEM A;  1L0I A;  2EHS A;  4PWV B;  5BS1 A;  1K30 A;  3CXC O;  5CZD B;  2N50 A;  2M8P A;  2CGQ A;  4COC A;  4QKO A;  4PXH B;  2FHS C;  1T8K A;  2CG5 B;  7CEI A;  2KG9 A;  4WYM A;  2JYL A;  2GZE A;  2N6Z A;  1RO2 A;  1BXI A;  5BS2 A;  1M6N A;  3CCU P;  1CEI A;  3P05 A;  1RNI A;  2QNW A;  4GR2 A;  1E6J P;  2Z46 A;  1Z6M A;  2M5R A;  2JB0 A;  2MY5 A;  1YJ9 P;  2Z45 A;  2JBG A;  5EW5 E;  1DNY A;  2MR8 A;  5I4T G;  2PEO A;  4R0M A;  3EJE A;  2X2B A;  2OTJ P;  3DS4 A;  4U0C A;  1VQK P;  2GZF A;  2KOS A;  4F37 A;  1A43 A;  4XFY A;  1YHQ P;  2AFE A;  2KOD A;  4BPH A;  3G6E P;  2K5X A;  3EJD A;  2P9X A;  5F2O A;  3LMO A;  2K0Y A;  2EIA A;  2GZG A;  1QVG O;  1VQM P;  2MVV A;  1D1D A;  2FQ2 A;  1AUM A;  5HVC A;  1L0H A;  1VQ5 P;  2FVA A;  1M6E X;  1EMV A;  3MGE A;  3CCE P;  2LKI A;  3WBH A;  2KOP A;  1DV5 A;  3CCS P;  3G29 A;  3CCM P;  2N5H A;  1YIJ P;  3NTE A;  1KD1 Q;  2NO8 A;  2JGP A;  1IUQ A;  2EFJ A;  4DG9 A;  2MD9 A;  2AFD A;  2GDX A;  2LML A;  2E1M A;  4COP A;  1OR5 A;  3CME P;  2K0D X;  3CCR P;  3H0D A;  3H47 A;  2VLP A;  2PEJ A;  2XZ1 C;  2AVA A;  1HQB A;  1K8A Q;  1VQO P;  5KP6 B;  2KOR A;  3RG2 A;  4MRT C;  4U0A A;  3Q20 A;  1X3O A;  2PEK A;  2JU1 A;  2M8N A;  3CE7 A;  2VLN A;  1Q7Y Q;  2MVU A;  1RO0 A;  1EOQ A;  2K92 A;  2FAD A;  2N5I A;  3G4S P;  2LOL A;  2QA4 P;  3DS5 A;  2EHT A;  2JYG A;  5JPA A;  4U0E A;  1Q86 Q;  3GZM A;  2LTE A;  2FQ1 A;  3G21 A;  1EIA A;  2OAR A;  3CPW O;  3G28 A;  1KLP A;  1AF8 A;  1IMP A;  1M90 Q;  3VRL C;  1KC8 Q;  3CC7 P;  1M74 A;  2DGY A;  1FR2 A;  5HV8 A;  4NEO A;  2FQ0 A;  4IPY A;  2VLQ A;  3U43 A;  2KGE A;  1A8O A;  3DPH A;  2VSQ A;  2LIW A;  2KGD A;  3EJB A;  1KQS O;  2FVE A;  1VQP P;  4BPG A;  1VQ4 P;  2QEX P;  1VQ8 P;  1Q81 Q;  2GYK A;  4CA3 A;  1GXH A;  4U0B A;  1YJN P;  2KGC A;  3GZL A;  4IZ6 A;  3CCQ P;  1YJW P;  4QNB A;  4PH0 A;  3G1G A;  3CC4 P;  2N6Y A;  2CWO A;  2MR7 A;  5F2N A;  2KOQ A;  2KOO A;  4M0I A;  1YIT P;  2MF4 A;  2PEQ A;  3LRY A;  1UNK A;  2KG6 A;  1GXG A;  2JO0 A;  2GDW A;  2KG8 A;  3G26 A;  4GR6 A;  3CC2 P;  3CCL P;  1ACP A;  2FAC A;  5KP7 B;  2OTL P;  2XXM A;  3CD6 P;  4XFX A;  4BPF A;  2PEI A;  2N98 A;  5HGN A;  2AF8 A;  1IMQ A;  2ERH A;  2GZJ A;  2GDY A;  3DS0 A;  2CQ8 A;  1VQ6 P;  2JQ4 A;  1NQ4 A;  2L6E A;  2VLO A;  3DTJ A;  3CMA P;  1W2B O;  2KR5 A;  3DS3 A;  4U0D A;  1VQ9 P;  3CCV P;  3M1M A;  4H2X C;  4XRQ A;  2K0X A;  1JJ2 O;  3G1I A;  2DNW A;  1AYI A;  1Q82 Q;  3CCJ P;  1NJI Q;  3RG6 C;  5KP8 B;  1UJZ A;  4PH1 A;  3I56 P;  1VQ7 P;  2GZI A;  4U0F A;  2K94 A;  2CNR A;  5HGM A;  2XZ0 D;  2L9F A;  2FVF A;  5F2K A;  2KGA A;  4XRO A;  1GPJ A;  3E2D A;  3DS1 A;  2PNG A;  1E0H A;  4H2Y C;  2BHV A;  1K9M Q;  4UHP B;  5HGO A;  4H2W C;  1YI2 P;  5EJD A;  2XV6 A;  2ROQ A;  2KW2 A;  1K73 Q;  1QVF O;  3B4Q A;  3I55 P;  2L0Q A;  2JU2 A;  5DCK A;  4XFZ A;  2PEN A;  2LIU A;  4HKG A;  2L4B A;  2M8L A;  2LF4 A;  3NY7 B;  1S72 P;  2KWL A;  2BUO A;  3DS2 A;  1VQL P;  1HY8 A;  2EG5 A;  3GKL C;  3OW2 O;  3G0V A;  1MZ8 A;  3B5I A;  3HZQ A;  5HGL A;  2FAE A;  2L22 A;  1QRJ A;  2PY8 A;  2Z44 A;  2K2Q A;  2XT1 A;  3G71 P;  1N8R Q;  1VKU A;  2LL8 A;  3H4E A;  3HYB A;  2WPT A; 
#chains in the Genus database with same CATH homology
 7CEI A;  1IMQ A;  2ERH A;  2GZJ A;  1UNK A;  2VLQ A;  2VLP A;  3U43 A;  2JBG A;  5EW5 E;  1MZ8 A;  1AYI A;  1GXG A;  2GZE A;  3GJN A;  2JAZ A;  1BXI A;  2GZG A;  1IMP A;  1ZNV A;  2NO8 A;  2VLO A;  1UJZ A;  1CEI A;  2VLN A;  1E0H A;  2GZI A;  1EMV A;  4UHP B;  2GZF A;  1FR2 A;  2JB0 A;  4F37 A;  4QKO A;  2GYK A;  2WPT A;  1GXH A;  2K0D X;  3GKL C;  2K5X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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