3HZQA

Structure of a tetrameric mscl in an expanded intermediate state
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
94
structure length
94
Chain Sequence
MLKEFKEFALKGNVLDLAIAVVMGAAFNKIICSLVENIIMPLIGKIFGSVDFAKEWSFWGIKYGLFIQSVIDFIIIAFALFIFVKIANTLMKKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a tetrameric MscL in an expanded intermediate state.
pubmed doi rcsb
molecule tags Membrane protein
source organism Staphylococcus aureus subsp. aureus mw2
molecule keywords Large-conductance mechanosensitive channel
total genus 24
structure length 94
sequence length 94
ec nomenclature
pdb deposition date 2009-06-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.120 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A 3hzqA00
3HZQA 2OARA
chains in the Genus database with same CATH superfamily
2EFJA 3HYBA 2JAZA 5EJDA 3H4EA 2KG6A 2AFDA 4H2XC 2VLNA 3G21A 3CE7A 5KP7B 3Q20A 1T8KA 4IPYA 2OTLP 2XZ0D 5HGNA 3CMEP 3GKLC 2JBGA 1VQOP 2PEKA 2DGYA 4U0BA 3M1MA 4R0MA 1FR2A 1YJWP 2K0XA 2XT1A 1VQ8P 4PH1A 2PNGA 3CC7P 2FQ2A 1Q81Q 2M8NA 1K73Q 1OR5A 1IMQA 2GZJA 3CC4P 2PEIA 3DS2A 5JPAA 3DS3A 3CCQP 2PEJA 2FQ1A 3EJDA 1M74A 1KQSO 4DG9A 1QVGO 3GZLA 3HZQA 1Q86Q 1N8RQ 2KGEA 2FVAA 2LTEA 2XXMA 4HKGA 1W2BO 2GZFA 5HGMA 2KOQA 4U0AA 1ACPA 4PWVB 1VQLP 2P9XA 2MR8A 3CMAP 4U0EA 1KD1Q 2L6EA 1VQ5P 2KORA 2ONTA 4QKOA 3E2DA 3CCJP 1VQ6P 1L0HA 2AF8A 5F2KA 1AF8A 3NTEA 5KP6B 2JQ4A 4MRTC 1AUMA 1UNKA 2EHTA 2CG5B 4UHPB 1YJ9P 3CCVP 5CZDB 4BPHA 2CWOA 1VQKP 2PEMA 2L9FA 3G71P 3CCEP 3WBHA 4U0DA 4XFYA 2DNWA 2KG8A 5F2NA 2EHSA 3DPHA 1ZNVA 3P05A 3NY7B 2GYKA 1UJZA 2N6ZA 3I56P 2MF4A 1YHQP 3B4QA 1NJIQ 4PH0A 1VQNP 2LPKA 4COCA 5HGLA 2JGPA 3G28A 3VRLC 2LOLA 1IMPA 1CEIA 2KODA 4XRQA 4PXHB 1L0IA 3DS1A 2JU1A 2VLQA 1RO2A 3DTJA 2JYGA 1E6JP 2XV6A 4H2YC 3G1IA 2N5HA 2PENA 2CNRA 1HQBA 1YI2P 2K92A 2MY5A 2JO0A 2X2BA 2FVFA 1RO0A 2LIUA 4XROA 1ZMBA 3GJNA 2NO8A 3B5IA 3H0DA 4U0CA 2KG9A 1BXIA 5DCKA 1QVFO 2MD9A 2QNWA 2M8PA 1K9MQ 3MGEA 1KLPA 1BAJA 2KGAA 2BUOA 2FADA 4IZ6A 1AYIA 1VQ4P 5F2OA 3H47A 1M1KQ 1YJNP 3CCUP 3OW2O 4BPFA 3G29A 1Z6MA 2LF4A 2KGDA 2PY8A 4GR2A 2EG5A 4WYMA 1M90Q 2KWLA 2LL8A 5I4TG 2JU2A 4H2WC 1VQPP 2KGCA 2MR7A 2AFEA 2VSQA 2N98A 3G26A 1Q82Q 3RG6C 2Z45A 3CC2P 3LRYA 2QA4P 2N50A 2N5IA 4GR6A 2L4BA 2GZGA 4COPA 1S72P 2L0QA 2GDXA 2GDWA 2VLPA 1DV5A 2M8LA 2GDYA 2EIAA 1EOQA 5KP8B 2ROQA 2GZIA 4M0IA 1M6NA 1NQ4A 2FHSC 2KW2A 2XZ1C 1VQ9P 4CA3A 7CEIA 1EMVA 1Q7YQ 4U0FA 2LIWA 3I55P 1M6EX 2AVAA 2E1MA 5EW5E 3G6EP 3CXCO 2Z44A 3CPWO 2CGQA 2OARA 3DS0A 2K0YA 1GXGA 2K0DX 3RG2A 4NEOA 2KOSA 2GZEA 2PEQA 2FVEA 2MVUA 2KOPA 3G4SP 5BS2A 1A8OA 1MZ8A 2K93A 2FACA 4XFZA 1DNYA 3CCMP 2JB0A 2LKIA 3DS4A 2CQ8A 1VQ7P 1VHNA 3CCRP 2MVVA 3CCLP 2VLOA 3LMOA 1F80D 1GPJA 2BHVA 1A43A 1K8AQ 1IUQA 2ERHA 1D1DA 2L22A 4F37A 3U43A 3G1GA 3DS5A 2M5RA 1K30A 4XFXA 2QEXP 5HVCA 2Z46A 2JYLA 3G0VA 1QRJA 3EJEA 1KC8Q 2OTJP 1HY8A 1RNIA 1VKUA 1YIJP 2K5XA 5HV8A 3CCSP 3EJBA 1X3OA 2KR5A 2K2QA 2PEOA 2N6YA 2FQ0A 2LMLA 5BS1A 3GZMA 4BPGA 5HGOA 2K94A 1E0HA 2KOOA 1VQMP 2WPTA 1JJ2O 4QNBA 2FAEA 1GXHA 1YITP 1EIAA 3CD6P
chains in the Genus database with same CATH topology
2EFJA 1VQ5P 3H0DA 1M6EX 3HYBA 2ONTA 2E1MA 4U0CA 3E2DA 3G6EP 3CXCO 2Z44A 3CPWO 5DCKA 2OARA 3H4EA 3CCJP 1QVFO 1VQ6P 2M8PA 3DS0A 3G21A 1K9MQ 3MGEA 5F2KA 1BAJA 3Q20A 3NTEA 2BUOA 4IPYA 2OTLP 1VQ4P 5HGNA 2PEQA 3CMEP 5F2OA 1AUMA 3H47A 3G4SP 5BS2A 1VQOP 1YJ9P 1A8OA 1M1KQ 3CCVP 4XFZA 2PEKA 2DGYA 2CWOA 1VQKP 3CCMP 1YJNP 4U0BA 3CCUP 3M1MA 3DS4A 2PEMA 3G71P 3OW2O 3CCEP 1VQ7P 3G29A 3WBHA 3CCRP 2LF4A 1YJWP 2PY8A 3CCLP 2XT1A 4U0DA 4XFYA 1VQ8P 4GR2A 4PH1A 2EG5A 5F2NA 2BHVA 4WYMA 1A43A 3DPHA 1K8AQ 3CC7P 1M90Q 3P05A 5I4TG 1Q81Q 1IUQA 2M8NA 1D1DA 1K73Q 3I56P 1VQPP 1YHQP 3G1GA 1NJIQ 3CC4P 4PH0A 3DS5A 1K30A 2PEIA 1VQNP 4XFXA 2QEXP 3DS2A 5JPAA 4COCA 3DS3A 2Z46A 3CCQP 3G26A 5HGLA 2PEJA 1Q82Q 3RG6C 2JYLA 2Z45A 3G28A 3G0VA 1QRJA 3LRYA 3CC2P 1KC8Q 1M74A 2QA4P 2OTJP 3VRLC 1KQSO 4GR6A 1RNIA 2KODA 1YIJP 1QVGO 4XRQA 3DS1A 4COPA 3CCSP 3HZQA 1Q86Q 1N8RQ 1S72P 1RO2A 3DTJA 2JYGA 1E6JP 2XV6A 2PEOA 2XXMA 3G1IA 1W2BO 2M8LA 2EIAA 1EOQA 5BS1A 2PENA 4M0IA 1M6NA 1YI2P 5HGMA 2JO0A 5HGOA 4U0AA 1RO0A 1VQ9P 1VQMP 1JJ2O 1VQLP 2P9XA 4QNBA 1Q7YQ 4XROA 3CMAP 1ZMBA 4U0EA 4U0FA 1KD1Q 1YITP 1EIAA 3B5IA 3I55P 3CD6P 2L6EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HZQ A;  2OAR A; 
#chains in the Genus database with same CATH topology
 2EFJ A;  3HYB A;  2JAZ A;  5EJD A;  3H4E A;  2KG6 A;  2AFD A;  4H2X C;  2VLN A;  3G21 A;  3CE7 A;  5KP7 B;  3Q20 A;  1T8K A;  4IPY A;  2OTL P;  2XZ0 D;  5HGN A;  3CME P;  3GKL C;  2JBG A;  1VQO P;  2PEK A;  2DGY A;  4U0B A;  3M1M A;  4R0M A;  1FR2 A;  1YJW P;  2K0X A;  2XT1 A;  1VQ8 P;  4PH1 A;  2PNG A;  3CC7 P;  2FQ2 A;  1Q81 Q;  2M8N A;  1K73 Q;  1OR5 A;  1IMQ A;  2GZJ A;  3CC4 P;  2PEI A;  3DS2 A;  5JPA A;  3DS3 A;  3CCQ P;  2PEJ A;  2FQ1 A;  3EJD A;  1M74 A;  1KQS O;  4DG9 A;  1QVG O;  3GZL A;  3HZQ A;  1Q86 Q;  1N8R Q;  2KGE A;  2FVA A;  2LTE A;  2XXM A;  4HKG A;  1W2B O;  2GZF A;  5HGM A;  2KOQ A;  4U0A A;  1ACP A;  4PWV B;  1VQL P;  2P9X A;  2MR8 A;  3CMA P;  4U0E A;  1KD1 Q;  2L6E A;  1VQ5 P;  2KOR A;  2ONT A;  4QKO A;  3E2D A;  3CCJ P;  1VQ6 P;  1L0H A;  2AF8 A;  5F2K A;  1AF8 A;  3NTE A;  5KP6 B;  2JQ4 A;  4MRT C;  1AUM A;  1UNK A;  2EHT A;  2CG5 B;  4UHP B;  1YJ9 P;  3CCV P;  5CZD B;  4BPH A;  2CWO A;  1VQK P;  2PEM A;  2L9F A;  3G71 P;  3CCE P;  3WBH A;  4U0D A;  4XFY A;  2DNW A;  2KG8 A;  5F2N A;  2EHS A;  3DPH A;  1ZNV A;  3P05 A;  3NY7 B;  2GYK A;  1UJZ A;  2N6Z A;  3I56 P;  2MF4 A;  1YHQ P;  3B4Q A;  1NJI Q;  4PH0 A;  1VQN P;  2LPK A;  4COC A;  5HGL A;  2JGP A;  3G28 A;  3VRL C;  2LOL A;  1IMP A;  1CEI A;  2KOD A;  4XRQ A;  4PXH B;  1L0I A;  3DS1 A;  2JU1 A;  2VLQ A;  1RO2 A;  3DTJ A;  2JYG A;  1E6J P;  2XV6 A;  4H2Y C;  3G1I A;  2N5H A;  2PEN A;  2CNR A;  1HQB A;  1YI2 P;  2K92 A;  2MY5 A;  2JO0 A;  2X2B A;  2FVF A;  1RO0 A;  2LIU A;  4XRO A;  1ZMB A;  3GJN A;  2NO8 A;  3B5I A;  3H0D A;  4U0C A;  2KG9 A;  1BXI A;  5DCK A;  1QVF O;  2MD9 A;  2QNW A;  2M8P A;  1K9M Q;  3MGE A;  1KLP A;  1BAJ A;  2KGA A;  2BUO A;  2FAD A;  4IZ6 A;  1AYI A;  1VQ4 P;  5F2O A;  3H47 A;  1M1K Q;  1YJN P;  3CCU P;  3OW2 O;  4BPF A;  3G29 A;  1Z6M A;  2LF4 A;  2KGD A;  2PY8 A;  4GR2 A;  2EG5 A;  4WYM A;  1M90 Q;  2KWL A;  2LL8 A;  5I4T G;  2JU2 A;  4H2W C;  1VQP P;  2KGC A;  2MR7 A;  2AFE A;  2VSQ A;  2N98 A;  3G26 A;  1Q82 Q;  3RG6 C;  2Z45 A;  3CC2 P;  3LRY A;  2QA4 P;  2N50 A;  2N5I A;  4GR6 A;  2L4B A;  2GZG A;  4COP A;  1S72 P;  2L0Q A;  2GDX A;  2GDW A;  2VLP A;  1DV5 A;  2M8L A;  2GDY A;  2EIA A;  1EOQ A;  5KP8 B;  2ROQ A;  2GZI A;  4M0I A;  1M6N A;  1NQ4 A;  2FHS C;  2KW2 A;  2XZ1 C;  1VQ9 P;  4CA3 A;  7CEI A;  1EMV A;  1Q7Y Q;  4U0F A;  2LIW A;  3I55 P;  1M6E X;  2AVA A;  2E1M A;  5EW5 E;  3G6E P;  3CXC O;  2Z44 A;  3CPW O;  2CGQ A;  2OAR A;  3DS0 A;  2K0Y A;  1GXG A;  2K0D X;  3RG2 A;  4NEO A;  2KOS A;  2GZE A;  2PEQ A;  2FVE A;  2MVU A;  2KOP A;  3G4S P;  5BS2 A;  1A8O A;  1MZ8 A;  2K93 A;  2FAC A;  4XFZ A;  1DNY A;  3CCM P;  2JB0 A;  2LKI A;  3DS4 A;  2CQ8 A;  1VQ7 P;  1VHN A;  3CCR P;  2MVV A;  3CCL P;  2VLO A;  3LMO A;  1F80 D;  1GPJ A;  2BHV A;  1A43 A;  1K8A Q;  1IUQ A;  2ERH A;  1D1D A;  2L22 A;  4F37 A;  3U43 A;  3G1G A;  3DS5 A;  2M5R A;  1K30 A;  4XFX A;  2QEX P;  5HVC A;  2Z46 A;  2JYL A;  3G0V A;  1QRJ A;  3EJE A;  1KC8 Q;  2OTJ P;  1HY8 A;  1RNI A;  1VKU A;  1YIJ P;  2K5X A;  5HV8 A;  3CCS P;  3EJB A;  1X3O A;  2KR5 A;  2K2Q A;  2PEO A;  2N6Y A;  2FQ0 A;  2LML A;  5BS1 A;  3GZM A;  4BPG A;  5HGO A;  2K94 A;  1E0H A;  2KOO A;  1VQM P;  2WPT A;  1JJ2 O;  4QNB A;  2FAE A;  1GXH A;  1YIT P;  1EIA A;  3CD6 P; 
#chains in the Genus database with same CATH homology
 2EFJ A;  1VQ5 P;  3H0D A;  1M6E X;  3HYB A;  2ONT A;  2E1M A;  4U0C A;  3E2D A;  3G6E P;  3CXC O;  2Z44 A;  3CPW O;  5DCK A;  2OAR A;  3H4E A;  3CCJ P;  1QVF O;  1VQ6 P;  2M8P A;  3DS0 A;  3G21 A;  1K9M Q;  3MGE A;  5F2K A;  1BAJ A;  3Q20 A;  3NTE A;  2BUO A;  4IPY A;  2OTL P;  1VQ4 P;  5HGN A;  2PEQ A;  3CME P;  5F2O A;  1AUM A;  3H47 A;  3G4S P;  5BS2 A;  1VQO P;  1YJ9 P;  1A8O A;  1M1K Q;  3CCV P;  4XFZ A;  2PEK A;  2DGY A;  2CWO A;  1VQK P;  3CCM P;  1YJN P;  4U0B A;  3CCU P;  3M1M A;  3DS4 A;  2PEM A;  3G71 P;  3OW2 O;  3CCE P;  1VQ7 P;  3G29 A;  3WBH A;  3CCR P;  2LF4 A;  1YJW P;  2PY8 A;  3CCL P;  2XT1 A;  4U0D A;  4XFY A;  1VQ8 P;  4GR2 A;  4PH1 A;  2EG5 A;  5F2N A;  2BHV A;  4WYM A;  1A43 A;  3DPH A;  1K8A Q;  3CC7 P;  1M90 Q;  3P05 A;  5I4T G;  1Q81 Q;  1IUQ A;  2M8N A;  1D1D A;  1K73 Q;  3I56 P;  1VQP P;  1YHQ P;  3G1G A;  1NJI Q;  3CC4 P;  4PH0 A;  3DS5 A;  1K30 A;  2PEI A;  1VQN P;  4XFX A;  2QEX P;  3DS2 A;  5JPA A;  4COC A;  3DS3 A;  2Z46 A;  3CCQ P;  3G26 A;  5HGL A;  2PEJ A;  1Q82 Q;  3RG6 C;  2JYL A;  2Z45 A;  3G28 A;  3G0V A;  1QRJ A;  3LRY A;  3CC2 P;  1KC8 Q;  1M74 A;  2QA4 P;  2OTJ P;  3VRL C;  1KQS O;  4GR6 A;  1RNI A;  2KOD A;  1YIJ P;  1QVG O;  4XRQ A;  3DS1 A;  4COP A;  3CCS P;  3HZQ A;  1Q86 Q;  1N8R Q;  1S72 P;  1RO2 A;  3DTJ A;  2JYG A;  1E6J P;  2XV6 A;  2PEO A;  2XXM A;  3G1I A;  1W2B O;  2M8L A;  2EIA A;  1EOQ A;  5BS1 A;  2PEN A;  4M0I A;  1M6N A;  1YI2 P;  5HGM A;  2JO0 A;  5HGO A;  4U0A A;  1RO0 A;  1VQ9 P;  1VQM P;  1JJ2 O;  1VQL P;  2P9X A;  4QNB A;  1Q7Y Q;  4XRO A;  3CMA P;  1ZMB A;  4U0E A;  4U0F A;  1KD1 Q;  1YIT P;  1EIA A;  3B5I A;  3I55 P;  3CD6 P;  2L6E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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